Ehab A. Abourashed PhD
Professor
Institution: Medical College of Wisconsin
Department: School of Pharmacy Administration
Division: Administration
Program: Program Development
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Research Experience
Anti-Bacterial AgentsAntioxidantsBenzoquinonesBiotransformationChromatography, High Pressure LiquidDietary SupplementsIsoflavonesMagnetic Resonance SpectroscopyMicrobial Sensitivity TestsMolecular StructurePhytotherapyPlant ExtractsPlants, MedicinalQuality ControlSesquiterpenesMethodologies and Techniques
AntioxidantsBiotransformationChromatography, High Pressure LiquidDietary SupplementsGas Chromatography-Mass SpectrometryMagnetic Resonance SpectroscopyMolecular StructurePhytotherapyPlant ExtractsPlants, MedicinalQuality ControlSpectrophotometry, InfraredSpectroscopy, Fourier Transform InfraredTandem Mass SpectrometryLeadership Positions
Chair, Curriculum Committee, School of Pharmacy, 2017-presentEducational Expertise
Anti-Bacterial AgentsAntioxidantsChromatography, High Pressure LiquidDietary SupplementsMagnetic Resonance SpectroscopyMicrobial Sensitivity TestsMolecular StructurePhytotherapyPlant ExtractsPlants, MedicinalPublications (61)
Retained strength of expired albuterol and montelukast pharmaceuticals (Abourashed EA, Kutty RG, Bevry M, Hoffmann P) Annals of Allergy, Asthma and Immunology February 2022;128(2):222-223 SCOPUS ID: 2-s2.0-85118702838 02/01/2022 2 CitationsStability Determination of an Extemporaneously Compounded Ambrisentan Suspension by High Performance Liquid Chromatography Analysis. (Cramer J, Bevry M, Handler S, Tillman K, Abourashed EA) J Pediatr Pharmacol Ther 2021;26(3):265-270 PMID: 33833628 PMCID: PMC8021248 SCOPUS ID: 2-s2.0-85104684194 04/10/2021 1 CitationPhenolic compounds from nutmeg (Myristica fragrans Houtt.) inhibit the endocannabinoid-modulating enzyme fatty acid amide hydrolase. (El-Alfy AT, Abourashed EA, Patel C, Mazhari N, An H, Jeon A) J Pharm Pharmacol 2019 Dec;71(12):1879-1889 PMID: 31595522 PMCID: PMC7938946 SCOPUS ID: 2-s2.0-85074090803 10/09/2019 19 CitationsA sustained elective course on substance abuse and addiction delivered in an academic pharmacy programme (Abourashed EA, Cross W) Pharmacy Education 2019;19(1):190-198 SCOPUS ID: 2-s2.0-85070471715 01/01/2019 1 CitationReview of Stilbenes: Applications in Chemistry, Life Sciences and Materials Science (Abourashed EA) Journal of Natural Products 24 February 2017;80(2):577 SCOPUS ID: 2-s2.0-85013857798 02/24/2017 11 CitationsReview of Stilbenes: Applications in Chemistry, Life Sciences and Materials Science Stilbenes: Applications in Chemistry, Life Sciences and Materials Science . By Gertz Likhtenshtein. Wiley-VCH , Weinheim, Germany . 2009 . 360 pp. $224 Hardcover. ISBN 978-3-527-32388-3 . (Abourashed EA) J Nat Prod 2017 Feb 24;80(2):577 PMID: 28191947 02/14/2017 Hydroxybenzoic Acids Are Significant Contributors to the Antioxidant Effect of Borututu Bark, Cochlospermum angolensis Welw. ex Oliv. (Abourashed EA, Fu HW) Antioxidants (Basel) 2017 Jan 28;6(1) PMID: 28134834 PMCID: PMC5384172 SCOPUS ID: 2-s2.0-85012045844 01/31/2017 5 CitationsChemical diversity and pharmacological significance of the secondary metabolites of nutmeg (Myristica fragrans Houtt.). (Abourashed EA, El-Alfy AT) Phytochem Rev 2016 Dec;15(6):1035-1056 PMID: 28082856 PMCID: PMC5222521 SCOPUS ID: 2-s2.0-84966525966 01/14/2017 99 CitationsHPLC-Guided Isolation, Purification and Characterization of Phenylpropanoid and Phenolic Constituents of Nutmeg Kernel (Myristica fragrans). (Chiu S, Wang T, Belski M, Abourashed EA) Nat Prod Commun 2016 Apr;11(4):483-8 PMID: 27396199 PMCID: PMC4943679 SCOPUS ID: 2-s2.0-85016745170 07/12/2016 27 CitationsIndirect modulation of the endocannabinoid system by specific fractions of nutmeg total extract. (El-Alfy AT, Joseph S, Brahmbhatt A, Akati S, Abourashed EA) Pharm Biol 2016 Dec;54(12):2933-2938 PMID: 27296774 SCOPUS ID: 2-s2.0-84974800846 06/15/2016 9 CitationsPotential of Horse Apple Isoflavones in Targeting Inflammation and Tau Protein Fibrillization. (Abourashed EA, Abraha A, Khan SI, McCants T, Awan S) Nat Prod Commun 2015 Sep;10(9):1577-80 PMID: 26594763 SCOPUS ID: 2-s2.0-84954624058 11/26/2015 7 CitationsRecently disclosed chemical entities as potential candidates for management of tuberculosis. (Stec J, Abourashed EA) Pharm Pat Anal 2015;4(4):317-47 PMID: 26174569 SCOPUS ID: 2-s2.0-85050578152 07/16/2015 3 CitationsEvaluation of cost versus antioxidant determinants in green tea dietary supplements. (A Roberson CL, Abourashed EA, Elsharkawy N) J Am Pharm Assoc (2003) 2015;55(4):381-9 PMID: 26070074 SCOPUS ID: 2-s2.0-84936934619 06/13/2015 2 CitationsSynthesis and in vitro evaluation of ferutinol aryl esters for estrogenic activity and affinity toward cannabinoid receptors (Osman AMG, Abourashed EA, Slade D, Ahmed SA, Gul W, Khan SI, Elfadl TA, Dale OR, Husni AS, Cutler SJ, Elsohly MA) Medicinal Chemistry Research 11 June 2015;24(6):2670-2678 SCOPUS ID: 2-s2.0-84930929150 06/11/2015 4 CitationsSynthesis and in Vitro Evaluation of Ferutinol Aryl Esters for Estrogenic Activity and their Affinity (A.M.G. Osman
E.A. Abourashe
D. Slade
S.A. Ahmed
W. Gul
S.I. Khan
T. Abo-Elfadl
O.R. Dale
A.S. Husni
S.J. Cutler
M.A. ElSohly) Med. Chem. Res. Osman, A.M.G., Abourashed, E.A., Slade, D. et al. Med Chem Res (2015) 24: 2670. doi:10.1007/s00044-015-1319-7 06/01/2015 Content Variation of Catechin Markers, Total Phenolics and Caffeine in Green Tea Dietary Supplements. (Abourashed EA, Roberson CL, Elsharkawy N) J Diet Suppl 2016;13(2):171-84 PMID: 25299974 SCOPUS ID: 2-s2.0-84947047434 10/10/2014 10 CitationsHPLC determination of isoflavone levels in osage orange from the Midwest and southern United States. (Darji K, Miglis C, Wardlow A, Abourashed EA) J Agric Food Chem 2013 Jul 17;61(28):6806-11 PMID: 23772950 PMCID: PMC3774050 SCOPUS ID: 2-s2.0-84880359224 06/19/2013 13 CitationsBioavailability of Plant-Derived Antioxidants. (Abourashed EA) Antioxidants (Basel) 2013 Nov 05;2(4):309-25 PMID: 26784467 PMCID: PMC4665521 SCOPUS ID: 2-s2.0-84942745017 01/01/2013 74 CitationsBioconversion of silybin to phase I and II microbial metabolites with retained antioxidant activity. (Abourashed EA, Mikell JR, Khan IA) Bioorg Med Chem 2012 May 01;20(9):2784-8 PMID: 22503365 SCOPUS ID: 2-s2.0-84859891632 04/17/2012 34 CitationsNature against depression. (El-Alfy AT, Abourashed EA, Matsumoto RR) Curr Med Chem 2012;19(14):2229-41 PMID: 22414105 SCOPUS ID: 2-s2.0-84860661296 03/15/2012 19 CitationsAntimycobacterial activity of ferutinin alone and in combination with antitubercular drugs against a rapidly growing surrogate of Mycobacterium tuberculosis. (Abourashed EA, Galal AM, Shibl AM) Nat Prod Res 2011 Jul;25(12):1142-9 PMID: 21442547 SCOPUS ID: 2-s2.0-79960483919 03/29/2011 13 CitationsLiquid chromatographic high-throughput analysis of the new ultra-short acting hypnotic 'HIE-124' and its metabolite in mice serum using a monolithic silica column (Kadi A, Hefnawy M, Al-Majed A, Alonezi S, Asiri Y, Attia S, Abourashed E, El-Subbagh H) Analyst 7 February 2011;136(3):591-597 SCOPUS ID: 2-s2.0-78751542884 02/07/2011 10 CitationsNovel, selective sample stacking microemulsion electrokinetic capillary chromatography induced by reverse migrating pseudostationary phase for the determination of the new ultra-short acting hypnotic "HIE-124" in mice serum. (Hefnawy M, Al-Omar M, Julkhuf S, Attia S, Abourashed E, El-Subbagh H) Anal Chim Acta 2010 Jul 19;673(2):194-9 PMID: 20599035 SCOPUS ID: 2-s2.0-77954219288 07/06/2010 14 CitationsTowards a better understanding of the psychopharmacology of nutmeg: Activities in the mouse tetrad assay. (El-Alfy AT, Wilson L, ElSohly MA, Abourashed EA) J Ethnopharmacol 2009 Nov 12;126(2):280-6 PMID: 19703539 PMCID: PMC2783227 SCOPUS ID: 2-s2.0-70350346860 08/26/2009 28 CitationsHPTLC analysis of a new ultra-short-acting thiazolodiazepine hypnotic (HIE-124) in spiked human plasma (Abourashed E, Hefnawy M, El-Subbagh H) Journal of Planar Chromatography - Modern TLC 1 June 2009;22(3):183-186 SCOPUS ID: 2-s2.0-67650651970 06/01/2009 4 CitationsChemical composition and biological evaluation of the essential oil of Commiphora opobalsamum L. (Al-Massarany SM, Abbas FA, Demirci B, Baser KHC, Khan SI, Al-Rehaily AJ, Mossa JS, Abourashed EA) Journal of Herbs, Spices and Medicinal Plants 28 April 2008;13(4):111-121 SCOPUS ID: 2-s2.0-67650269887 04/28/2008 9 CitationsEnhancing effect of isoeugenol on the antimicrobial activity of isoniazid, 6-paradol and 6-shogaol (Abourashed EA, Galal AM, Shebl AM, Mossa JS) Journal of Herbs, Spices and Medicinal Plants 28 April 2008;13(4):95-103 SCOPUS ID: 2-s2.0-67650257681 04/28/2008 9 CitationsPhytochemical and biological studies on Saudi Commiphora opobalsamum L. (Abbas FA, Al-Massarany SM, Khan S, Al-Howiriny TA, Mossa JS, Abourashed EA) Nat Prod Res 2007 May;21(5):383-91 PMID: 17487607 SCOPUS ID: 2-s2.0-34548545051 05/10/2007 67 CitationsHPTLC determination of sildenafil in pharmaceutical products and aphrodisiac herbal preparations (Abourashed EA, Abdel-Kader MS, Habib AAM) Journal of Planar Chromatography - Modern TLC September 2005;18(105):372-376 SCOPUS ID: 2-s2.0-27944450125 09/01/2005 22 CitationsIn vitro binding experiments with a Valerian, hops and their fixed combination extract (Ze91019) to selected central nervous system receptors. (Abourashed EA, Koetter U, Brattström A) Phytomedicine 2004 Nov;11(7-8):633-8 PMID: 15636177 SCOPUS ID: 2-s2.0-10844275745 01/08/2005 84 CitationsThin-layer densitometry as an alternative tool in the quantitative evaluation of the free radical scavenging activity of natural antioxidants (Abourashed EA) Zeitschrift fur Naturforschung - Section B Journal of Chemical Sciences November 2005;60(11):1212-1218 SCOPUS ID: 2-s2.0-29944443816 01/01/2005 10 CitationsHPTLC determination of caffeine in stimulant herbal products and power drinks. (Abourashed EA, Mossa JS) J Pharm Biomed Anal 2004 Nov 15;36(3):617-20 PMID: 15522538 SCOPUS ID: 2-s2.0-7444262420 11/04/2004 53 CitationsLotaustralin from Rhodiola rosea roots. (Akgul Y, Ferreira D, Abourashed EA, Khan IA) Fitoterapia 2004 Sep;75(6):612-4 PMID: 15351122 SCOPUS ID: 2-s2.0-4444234632 09/08/2004 33 CitationsValidation and application of an HPTLC method for the determination of parthenolide in feverfew herbal products (Abourashed EA) Journal of Planar Chromatography - Modern TLC September 2004;17(5):375-378 SCOPUS ID: 2-s2.0-9744246873 09/01/2004 7 CitationsThe fixed combination of valerian and hops (Ze91019) acts via a central adenosine mechanism. (Schellenberg R, Sauer S, Abourashed EA, Koetter U, Brattström A) Planta Med 2004 Jul;70(7):594-7 PMID: 15254851 SCOPUS ID: 2-s2.0-3543004166 07/16/2004 46 CitationsTransport of harman alkaloids across Caco-2 cell monolayers. (Khan SI, Abourashed EA, Khan IA, Walker LA) Chem Pharm Bull (Tokyo) 2004 Apr;52(4):394-7 PMID: 15056950 SCOPUS ID: 2-s2.0-7444267875 04/02/2004 24 CitationsTransport of parthenolide across human intestinal cells (Caco-2). (Khan SI, Abourashed EA, Khan IA, Walker LA) Planta Med 2003 Nov;69(11):1009-12 PMID: 14735438 SCOPUS ID: 2-s2.0-0346689998 01/22/2004 31 CitationsEphedra in perspective--a current review. (Abourashed EA, El-Alfy AT, Khan IA, Walker L) Phytother Res 2003 Aug;17(7):703-12 PMID: 12916063 SCOPUS ID: 2-s2.0-0041976090 08/14/2003 223 CitationsHPLC fingerprinting and estimation of the bioactive components of Clutia richardiana L. as a potential hypoglycemic herbal tea. (Abourashed EA, Ganzera M, Khan IA, Khan S, Mossa JS, El-Feraly FS) Phytother Res 2003 Jun;17(6):657-60 PMID: 12820235 SCOPUS ID: 2-s2.0-0038802399 06/24/2003 14 CitationsHigh-speed extraction and HPLC fingerprinting of medicinal plants - II. Application to harman alkaloids of genus Passiflora (Abourashed EA, Vanderplank J, Khan IA) Pharmaceutical Biology April 2003;41(2):100-106 SCOPUS ID: 2-s2.0-0038798417 04/01/2003 30 CitationsHigh-Speed Extraction and HPLC Fingerprinting of Medicinal Plants – II. Application to Harman Alkaloids of Genus Passiflora (E.A. Abourashed
J. Vanderplank
I.A. Khan) Pharm. Biol. 2003, 41, 100-106. http://dx.doi.org/10.1076/phbi.41.2.100.14244 03/01/2003 Clinic at the health food store? Employee recommendations and product analysis. (Glisson JK, Rogers HE, Abourashed EA, Ogletree R, Hufford CD, Khan I) Pharmacotherapy 2003 Jan;23(1):64-72 PMID: 12523461 SCOPUS ID: 2-s2.0-0037226603 01/14/2003 34 CitationsInteractions of valerian extracts and a fixed valerian-hop extract combination with adenosine receptors. (Müller CE, Schumacher B, Brattström A, Abourashed EA, Koetter U) Life Sci 2002 Sep 06;71(16):1939-49 PMID: 12175708 SCOPUS ID: 2-s2.0-0037031791 08/15/2002 80 CitationsHigh-speed extraction and HPLC fingerprinting of medicinal plants - I. Application to Passiflora flavonoids (Abourashed EA, Vanderplank JR, Khan IA) Pharmaceutical Biology 2002;40(2):81-91 SCOPUS ID: 2-s2.0-0036063892 07/24/2002 46 CitationsThe inhibitory activity of natural products on plant p-hydroxyphenylpyruvate dioxygenase. (Meazza G, Scheffler BE, Tellez MR, Rimando AM, Romagni JG, Duke SO, Nanayakkara D, Khan IA, Abourashed EA, Dayan FE) Phytochemistry 2002 Jun;60(3):281-8 PMID: 12031447 SCOPUS ID: 2-s2.0-0037030803 05/29/2002 166 CitationsHigh-Speed Extraction and HPLC Fingerprinting of Medicinal Plants – I. Application to Passiflora Flavonoids (E.A. Abourashed
J.R. Vanderplank
I.A. Khan. ) Pharm. Biol. Pharm. Biol., 2002, 40, 81-91. http://dx.doi.org/10.1076/phbi.40.2.81.5844 03/01/2002 GC determination of parthenolide in feverfew products. (Abourashed EA, Khan IA) Pharmazie 2001 Dec;56(12):971-2 PMID: 11802663 SCOPUS ID: 2-s2.0-0035666370 01/23/2002 6 CitationsSeparation and quantification of the major daucane esters of Ferula hermonis by HPLC. (Abourashed EA, Galal AM, El-Feraly FS, Khan IA) Planta Med 2001 Oct;67(7):681-2 PMID: 11582552 SCOPUS ID: 2-s2.0-0034813877 10/03/2001 28 CitationsInhibitory effects of maesanin and analogs on arachidonic acid metabolizing enzymes. (Abourashed EA, Muhammad I, Resch M, Bauer R, el-Feraly FS, Hufford CD) Planta Med 2001 Jun;67(4):360-1 PMID: 11458456 SCOPUS ID: 2-s2.0-0034955366 07/19/2001 12 CitationsHigh-performance liquid chromatography determination of hydrastine and berberine in dietary supplements containing goldenseal. (Abourashed EA, Khan IA) J Pharm Sci 2001 Jul;90(7):817-22 PMID: 11458331 SCOPUS ID: 2-s2.0-0034938508 07/18/2001 61 CitationsDetermination of heavy metals and pesticides in ginseng products. (Khan IA, Allgood J, Walker LA, Abourashed EA, Schlenk D, Benson WH) J AOAC Int 2001;84(3):936-9 PMID: 11417656 SCOPUS ID: 2-s2.0-0035344907 06/22/2001 83 CitationsDaucane sesquiterpenes from Ferula hermonis. (Galal AM, Abourashed EA, Ross SA, ElSohly MA, Al-Said MS, El-Feraly FS) J Nat Prod 2001 Mar;64(3):399-400 PMID: 11277769 SCOPUS ID: 2-s2.0-0035091149 03/30/2001 51 CitationsMicrobial transformation of kawain and methysticin. (Abourashed EA, Khan IA) Chem Pharm Bull (Tokyo) 2000 Dec;48(12):1996-8 PMID: 11145158 SCOPUS ID: 2-s2.0-0034536068 01/06/2001 26 CitationsDetermination of parthenolide in selected feverfew products by liquid chromatography. (Abourashed EA, Khan IA, Abourashed EA, Khan IA) J AOAC Int 2000;83(4):789-92 PMID: 10995104 SCOPUS ID: 2-s2.0-0034219691 09/20/2000 18 Citations2-Hydroxy-5-(ethanolamino)-3-(10'-Z-pentadecenyl)-1,4-benzoquinone, new microbial phase II metabolite of maesanin. (Abourashed EA, el-Feraly FS, Khan IA, Hufford CD) Chem Pharm Bull (Tokyo) 2000 Jan;48(1):45-7 PMID: 10705473 SCOPUS ID: 2-s2.0-0033978179 03/08/2000 4 CitationsCarboxylic acid microbial metabolites of the natural benzoquinone, maesanin. (Abourashed EA, El-Feraly FS, Hufford CD) J Nat Prod 1999 Oct;62(10):1474 PMID: 10545055 SCOPUS ID: 2-s2.0-0032747152 11/02/1999 Two new flavone glycosides from paullinia pinnata. (Abourashed EA, Toyang NJ, Choinski J Jr, Khan IA) J Nat Prod 1999 Aug;62(8):1179-81 PMID: 10479333 SCOPUS ID: 2-s2.0-0032822894 09/10/1999 39 CitationsCarboxylic acid microbial metabolites of the natural benzoquinone, maesanin. (Abourashed EA, El-Feraly FS, Hufford CD) J Nat Prod 1999 May;62(5):714-6 PMID: 10346952 SCOPUS ID: 2-s2.0-0033000781 05/29/1999 6 CitationsMicrobial models of mammalian metabolism of xenobiotics: An updated review. (Abourashed EA, Clark AM, Hufford CD) Curr Med Chem 1999 May;6(5):359-74 PMID: 10101217 SCOPUS ID: 2-s2.0-0032895172 04/02/1999 105 CitationsMicrobial Transformation of Artemether (E.A. Abourashed
C.D. Hufford) J. Nat. Prod. J. Nat. Prod., 1996, 59 (3), pp 251–253 03/22/1996 Microbial transformation of artemether (Abourashed EA, Hufford CD) Journal of Natural Products March 1996;59(3):251-253 SCOPUS ID: 2-s2.0-0030000413 03/01/1996 27 Citations Last update: 12/10/2021