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Cheryl L. Stucky PhD

Professor

Institution: Medical College of Wisconsin
Department: Cell Biology, Neurobiology and Anatomy
Program: Administration

Member of the Cancer Center
Member of the Comprehensive Injury Center
Member of the Neuroscience Research Center

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Publications (113)

Use the force, fluke: Ligand-independent gating of Schistosoma mansoni ion channel TRPM_PZQ. (Chulkov EG, Isaeva E, Stucky CL, Marchant JS) Int J Parasitol 2023 Jan 04 PMID: 36610555 SCOPUS ID: 2-s2.0-85146298174 01/08/2023

Keratinocyte PIEZO1 modulates cutaneous mechanosensation. (Mikesell AR, Isaeva O, Moehring F, Sadler KE, Menzel AD, Stucky CL) Elife 2022 Sep 02;11 PMID: 36053009 PMCID: PMC9512397 SCOPUS ID: 2-s2.0-85139375441 09/03/2022 2 Citations

Contextual control of conditioned pain tolerance and endogenous analgesic systems. (Trask S, Mogil JS, Helmstetter FJ, Stucky CL, Sadler KE) Elife 2022 Mar 11;11 PMID: 35275062 PMCID: PMC8937231 SCOPUS ID: 2-s2.0-85127306322 03/12/2022 1 Citation

Ex Vivo Skin-Teased Fiber Recordings from Tibial Nerve (Sadler KE, Patitucci TN, Stucky CL) Neuromethods 2022;178:71-95 SCOPUS ID: 2-s2.0-85131121319 01/01/2022

When soft touch hurts: How hugs become painful after spinal cord injury (Stucky CL, Mikesell AR) Spinal Cord Injury Pain 1 January 2022:341-351 SCOPUS ID: 2-s2.0-85139309301 01/01/2022

Innovations and advances in modelling and measuring pain in animals. (Sadler KE, Mogil JS, Stucky CL) Nat Rev Neurosci 2022 Feb;23(2):70-85 PMID: 34837072 PMCID: PMC9098196 SCOPUS ID: 2-s2.0-85119984072 11/28/2021 29 Citations

Sensory-specific peripheral nerve pathology in a rat model of Fabry disease. (Waltz TB, Burand AJ Jr, Sadler KE, Stucky CL) Neurobiol Pain 2021;10:100074 PMID: 34541380 PMCID: PMC8437817 SCOPUS ID: 2-s2.0-85122793784 09/21/2021 1 Citation

Cutaneous pain in disorders affecting peripheral nerves. (Stucky CL, Mikesell AR) Neurosci Lett 2021 Nov 20;765:136233 PMID: 34506882 PMCID: PMC8579816 SCOPUS ID: 2-s2.0-85116033920 09/11/2021 2 Citations

Piezo2 mechanosensitive ion channel is located to sensory neurons and nonneuronal cells in rat peripheral sensory pathway: implications in pain. (Shin SM, Moehring F, Itson-Zoske B, Fan F, Stucky CL, Hogan QH, Yu H) Pain 2021 Nov 01;162(11):2750-2768 PMID: 34285153 PMCID: PMC8526381 SCOPUS ID: 2-s2.0-85119089549 07/22/2021 12 Citations

Transient receptor potential canonical 5 mediates inflammatory mechanical and spontaneous pain in mice. (Sadler KE, Moehring F, Shiers SI, Laskowski LJ, Mikesell AR, Plautz ZR, Brezinski AN, Mecca CM, Dussor G, Price TJ, McCorvy JD, Stucky CL) Sci Transl Med 2021 May 26;13(595) PMID: 34039739 PMCID: PMC8923002 SCOPUS ID: 2-s2.0-85106954302 05/28/2021 24 Citations

Human cells and networks of pain: Transforming pain target identification and therapeutic development. (Renthal W, Chamessian A, Curatolo M, Davidson S, Burton M, Dib-Hajj S, Dougherty PM, Ebert AD, Gereau RW 4th, Ghetti A, Gold MS, Hoben G, Menichella DM, Mercier P, Ray WZ, Salvemini D, Seal RP, Waxman S, Woolf CJ, Stucky CL, Price TJ) Neuron 2021 May 05;109(9):1426-1429 PMID: 33957072 PMCID: PMC9208579 SCOPUS ID: 2-s2.0-85105020162 05/07/2021 19 Citations

Fabry disease pain: patient and preclinical parallels. (Burand AJ Jr, Stucky CL) Pain 2021 May 01;162(5):1305-1321 PMID: 33259456 PMCID: PMC8054551 SCOPUS ID: 2-s2.0-85104899493 12/02/2020 12 Citations

Keratinocytes contribute to normal cold and heat sensation. (Sadler KE, Moehring F, Stucky CL) Elife 2020 Jul 30;9 PMID: 32729832 PMCID: PMC7402674 SCOPUS ID: 2-s2.0-85089162086 07/31/2020 29 Citations

Satellite glial cells in sensory ganglia express functional transient receptor potential ankyrin 1 that is sensitized in neuropathic and inflammatory pain. (Shin SM, Itson-Zoske B, Cai Y, Qiu C, Pan B, Stucky CL, Hogan QH, Yu H) Mol Pain 2020;16:1744806920925425 PMID: 32484015 PMCID: PMC7268132 SCOPUS ID: 2-s2.0-85085909943 06/03/2020 22 Citations

End points for sickle cell disease clinical trials: patient-reported outcomes, pain, and the brain. (Farrell AT, Panepinto J, Carroll CP, Darbari DS, Desai AA, King AA, Adams RJ, Barber TD, Brandow AM, DeBaun MR, Donahue MJ, Gupta K, Hankins JS, Kameka M, Kirkham FJ, Luksenburg H, Miller S, Oneal PA, Rees DC, Setse R, Sheehan VA, Strouse J, Stucky CL, Werner EM, Wood JC, Zempsky WT) Blood Adv 2019 Dec 10;3(23):3982-4001 PMID: 31809538 PMCID: PMC6963237 SCOPUS ID: 2-s2.0-85076356716 12/07/2019 34 Citations

The anthelmintic drug praziquantel activates a schistosome transient receptor potential channel. (Park SK, Gunaratne GS, Chulkov EG, Moehring F, McCusker P, Dosa PI, Chan JD, Stucky CL, Marchant JS) J Biol Chem 2019 Dec 06;294(49):18873-18880 PMID: 31653697 PMCID: PMC6901322 SCOPUS ID: 2-s2.0-85075816525 10/28/2019 50 Citations

Peripheral nerve pathology in sickle cell disease mice. (Sadler KE, Lewis TR, Waltz TB, Besharse JC, Stucky CL) Pain Rep 2019;4(4):e765 PMID: 31579856 PMCID: PMC6728004 SCOPUS ID: 2-s2.0-85074188722 10/04/2019 5 Citations

Editorial overview: physiology of pain (Donaldson LF, Stucky CL) Current Opinion in Physiology October 2019;11:iii-v SCOPUS ID: 2-s2.0-85076007755 10/01/2019

NOD-like receptor protein 3 inflammasome drives postoperative mechanical pain in a sex-dependent manner. (Cowie AM, Menzel AD, O'Hara C, Lawlor MW, Stucky CL) Pain 2019 Aug;160(8):1794-1816 PMID: 31335648 PMCID: PMC6662742 SCOPUS ID: 2-s2.0-85069147648 07/25/2019 23 Citations

Gabapentin alleviates chronic spontaneous pain and acute hypoxia-related pain in a mouse model of sickle cell disease. (Sadler KE, Langer SN, Menzel AD, Moehring F, Erb AN, Brandow AM, Stucky CL) Br J Haematol 2019 Oct;187(2):246-260 PMID: 31247672 PMCID: PMC6786911 SCOPUS ID: 2-s2.0-85068153982 06/28/2019 4 Citations

A Novel Sex-Dependent Target for the Treatment of Postoperative Pain: The NLRP3 Inflammasome. (Cowie AM, Dittel BN, Stucky CL) Front Neurol 2019;10:622 PMID: 31244767 PMCID: PMC6581722 SCOPUS ID: 2-s2.0-85069217765 06/28/2019 21 Citations

Blocking COX-2 for sickle cell pain relief. (Sadler KE, Stucky CL) Blood 2019 May 02;133(18):1924-1925 PMID: 31048303 SCOPUS ID: 2-s2.0-85065494775 05/03/2019 2 Citations

A Mouse Model of Postoperative Pain. (Cowie AM, Stucky CL) Bio Protoc 2019 Jan 20;9(2) PMID: 30820443 PMCID: PMC6390978 03/02/2019

Neuronal transient receptor potential (TRP) channels and noxious sensory detection in sickle cell disease. (Sadler KE, Stucky CL) Neurosci Lett 2019 Feb 16;694:184-191 PMID: 30508569 PMCID: PMC6389361 SCOPUS ID: 2-s2.0-85058162306 12/07/2018 9 Citations

Uncovering the Cells and Circuits of Touch in Normal and Pathological Settings. (Moehring F, Halder P, Seal RP, Stucky CL) Neuron 2018 Oct 24;100(2):349-360 PMID: 30359601 PMCID: PMC6708582 SCOPUS ID: 2-s2.0-85055049128 10/26/2018 77 Citations

Children and adolescents with sickle cell disease have worse cold and mechanical hypersensitivity during acute painful events. (Brandow AM, Hansen K, Nugent M, Pan A, Panepinto JA, Stucky CL) Pain 2019 Feb;160(2):407-416 PMID: 30247266 PMCID: PMC6768435 SCOPUS ID: 2-s2.0-85060395341 09/25/2018 16 Citations

Optogenetic Inhibition of CGRPα Sensory Neurons Reveals Their Distinct Roles in Neuropathic and Incisional Pain. (Cowie AM, Moehring F, O'Hara C, Stucky CL) J Neurosci 2018 Jun 20;38(25):5807-5825 PMID: 29925650 PMCID: PMC6010565 SCOPUS ID: 2-s2.0-85050939678 06/22/2018 31 Citations

Quantitative Top-Down Mass Spectrometry Identifies Proteoforms Differentially Released during Mechanical Stimulation of Mouse Skin. (Moehring F, Waas M, Keppel TR, Rathore D, Cowie AM, Stucky CL, Gundry RL) J Proteome Res 2018 Aug 03;17(8):2635-2648 PMID: 29925238 PMCID: PMC6195672 SCOPUS ID: 2-s2.0-85048958690 06/22/2018 4 Citations

Chemokine (c-c motif) receptor 2 mediates mechanical and cold hypersensitivity in sickle cell disease mice. (Sadler KE, Zappia KJ, O'Hara CL, Langer SN, Weyer AD, Hillery CA, Stucky CL) Pain 2018 Aug;159(8):1652-1663 PMID: 29697532 PMCID: PMC6317856 SCOPUS ID: 2-s2.0-85058145603 04/27/2018 16 Citations

Neuropathic pain in a Fabry disease rat model. (Miller JJ, Aoki K, Moehring F, Murphy CA, O'Hara CL, Tiemeyer M, Stucky CL, Dahms NM) JCI Insight 2018 Mar 22;3(6) PMID: 29563343 PMCID: PMC5926911 SCOPUS ID: 2-s2.0-85058370681 03/23/2018 34 Citations

Keratinocytes mediate innocuous and noxious touch via ATP-P2X4 signaling. (Moehring F, Cowie AM, Menzel AD, Weyer AD, Grzybowski M, Arzua T, Geurts AM, Palygin O, Stucky CL) Elife 2018 Jan 16;7 PMID: 29336303 PMCID: PMC5777822 SCOPUS ID: 2-s2.0-85042135972 01/18/2018 88 Citations

Characterization of a mouse model of sickle cell trait: parallels to human trait and a novel finding of cutaneous sensitization. (Zappia KJ, Guo Y, Retherford D, Wandersee NJ, Stucky CL, Hillery CA) Br J Haematol 2017 Nov;179(4):657-666 PMID: 29027199 PMCID: PMC5696068 SCOPUS ID: 2-s2.0-85031318234 10/14/2017 4 Citations

Primary sensory neuron-specific interference of TRPV1 signaling by AAV-encoded TRPV1 peptide aptamer attenuates neuropathic pain. (Xiang H, Liu Z, Wang F, Xu H, Roberts C, Fischer G, Stucky C, Caron D, Pan B, Hogan Q, Yu H) Mol Pain 2017;13:1744806917717040 PMID: 28604222 PMCID: PMC5486490 SCOPUS ID: 2-s2.0-85038960017 06/13/2017 14 Citations

Sensory Neuron-Specific Deletion of TRPA1 Results in Mechanical Cutaneous Sensory Deficits. (Zappia KJ, O'Hara CL, Moehring F, Kwan KY, Stucky CL) eNeuro 2017;4(1) PMID: 28303259 PMCID: PMC5346175 SCOPUS ID: 2-s2.0-85031943687 03/18/2017 38 Citations

Sickle cell disease: a natural model of acute and chronic pain. (Brandow AM, Zappia KJ, Stucky CL) Pain 2017 Apr;158 Suppl 1(Suppl 1):S79-S84 PMID: 28221286 PMCID: PMC5350013 SCOPUS ID: 2-s2.0-85028915679 02/22/2017 32 Citations

Selective antagonism of TRPA1 produces limited efficacy in models of inflammatory- and neuropathic-induced mechanical hypersensitivity in rats. (Lehto SG, Weyer AD, Youngblood BD, Zhang M, Yin R, Wang W, Teffera Y, Cooke M, Stucky CL, Schenkel L, Geuns-Meyer S, Moyer BD, Wild KD, Gavva NR) Mol Pain 2016;12 PMID: 27899696 PMCID: PMC5131813 SCOPUS ID: 2-s2.0-85007432888 12/03/2016 19 Citations

Substance P is increased in patients with sickle cell disease and associated with haemolysis and hydroxycarbamide use. (Brandow AM, Wandersee NJ, Dasgupta M, Hoffmann RG, Hillery CA, Stucky CL, Panepinto JA) Br J Haematol 2016 Oct;175(2):237-245 PMID: 27539682 PMCID: PMC5063705 SCOPUS ID: 2-s2.0-84994551716 08/20/2016 27 Citations

Selective spider toxins reveal a role for the Nav1.1 channel in mechanical pain. (Osteen JD, Herzig V, Gilchrist J, Emrick JJ, Zhang C, Wang X, Castro J, Garcia-Caraballo S, Grundy L, Rychkov GY, Weyer AD, Dekan Z, Undheim EA, Alewood P, Stucky CL, Brierley SM, Basbaum AI, Bosmans F, King GF, Julius D) Nature 2016 Jun 23;534(7608):494-9 PMID: 27281198 PMCID: PMC4919188 SCOPUS ID: 2-s2.0-84975781988 06/10/2016 197 Citations

Mechanosensory and ATP Release Deficits following Keratin14-Cre-Mediated TRPA1 Deletion Despite Absence of TRPA1 in Murine Keratinocytes. (Zappia KJ, Garrison SR, Palygin O, Weyer AD, Barabas ME, Lawlor MW, Staruschenko A, Stucky CL) PLoS One 2016;11(3):e0151602 PMID: 26978657 PMCID: PMC4792390 SCOPUS ID: 2-s2.0-84961820405 03/16/2016 21 Citations

Nociceptor Sensitization Depends on Age and Pain Chronicity(1,2,3). (Weyer AD, Zappia KJ, Garrison SR, O'Hara CL, Dodge AK, Stucky CL) eNeuro 2016;3(1) PMID: 26866058 PMCID: PMC4745182 SCOPUS ID: 2-s2.0-85020661578 02/13/2016 34 Citations

CaMKII Controls Whether Touch Is Painful. (Yu H, Pan B, Weyer A, Wu HE, Meng J, Fischer G, Vilceanu D, Light AR, Stucky C, Rice FL, Hudmon A, Hogan Q) J Neurosci 2015 Oct 21;35(42):14086-102 PMID: 26490852 PMCID: PMC4683679 SCOPUS ID: 2-s2.0-84944929761 10/23/2015 21 Citations

Bedding Material Affects Mechanical Thresholds, Heat Thresholds, and Texture Preference. (Moehring F, O'Hara CL, Stucky CL) J Pain 2016 Jan;17(1):50-64 PMID: 26456764 PMCID: PMC4698037 SCOPUS ID: 2-s2.0-84951788627 10/13/2015 13 Citations

Correction: Cold shock induces apoptosis of dorsal root ganglion neurons plated on infrared windows. (Aboualizadeh E, Mattson EC, O'Hara CL, Smith AK, Stucky CL, Hirschmugl CJ) Analyst 2015 Sep 21;140(18):6421 PMID: 26273705 SCOPUS ID: 2-s2.0-84940118624 08/15/2015

Amplified Mechanically Gated Currents in Distinct Subsets of Myelinated Sensory Neurons following In Vivo Inflammation of Skin and Muscle. (Weyer AD, O'Hara CL, Stucky CL) J Neurosci 2015 Jun 24;35(25):9456-62 PMID: 26109668 PMCID: PMC4478256 SCOPUS ID: 2-s2.0-84933557705 06/26/2015 10 Citations

HTR7 Mediates Serotonergic Acute and Chronic Itch. (Morita T, McClain SP, Batia LM, Pellegrino M, Wilson SR, Kienzler MA, Lyman K, Olsen AS, Wong JF, Stucky CL, Brem RB, Bautista DM) Neuron 2015 Jul 01;87(1):124-38 PMID: 26074006 PMCID: PMC4536073 SCOPUS ID: 2-s2.0-84937516283 06/16/2015 112 Citations

Cold shock induces apoptosis of dorsal root ganglion neurons plated on infrared windows. (Aboualizadeh E, Mattson EC, O'Hara CL, Smith AK, Stucky CL, Hirschmugl CJ) Analyst 2015 Jun 21;140(12):4046-56 PMID: 26000346 PMCID: PMC4536072 SCOPUS ID: 2-s2.0-84930722181 05/23/2015 2 Citations

Repurposing a leukocyte elastase inhibitor for neuropathic pain. (Weyer AD, Stucky CL) Nat Med 2015 May;21(5):429-30 PMID: 25951529 SCOPUS ID: 2-s2.0-84929151869 05/08/2015 7 Citations

Loosening pain's grip by tightening TRPV1-TRPA1 interactions. (Weyer AD, Stucky CL) Neuron 2015 Feb 18;85(4):661-3 PMID: 25695265 SCOPUS ID: 2-s2.0-84925432939 02/20/2015 7 Citations

AMG2850, a potent and selective TRPM8 antagonist, is not effective in rat models of inflammatory mechanical hypersensitivity and neuropathic tactile allodynia. (Lehto SG, Weyer AD, Zhang M, Youngblood BD, Wang J, Wang W, Kerstein PC, Davis C, Wild KD, Stucky CL, Gavva NR) Naunyn Schmiedebergs Arch Pharmacol 2015 Apr;388(4):465-76 PMID: 25662185 PMCID: PMC4359714 SCOPUS ID: 2-s2.0-84925536714 02/11/2015 19 Citations

Correction: Transcriptional profiling at whole population and single cell levels reveals somatosensory neuron molecular diversity. (Chiu IM, Barrett LB, Williams EK, Strochlic DE, Lee S, Weyer AD, Lou S, Bryman G, Roberson DP, Ghasemlou N, Piccoli C, Ahat E, Wang V, Cobos EJ, Stucky CL, Ma Q, Liberles SD, Woolf C) Elife 2015 Feb 06;4:e06720 PMID: 25658835 PMCID: PMC4337598 02/07/2015

Transcriptional profiling at whole population and single cell levels reveals somatosensory neuron molecular diversity. (Chiu IM, Barrett LB, Williams EK, Strochlic DE, Lee S, Weyer AD, Lou S, Bryman GS, Roberson DP, Ghasemlou N, Piccoli C, Ahat E, Wang V, Cobos EJ, Stucky CL, Ma Q, Liberles SD, Woolf CJ) Elife 2014 Dec 19;3 PMID: 25525749 PMCID: PMC4383053 SCOPUS ID: 2-s2.0-84979258664 12/20/2014 150 Citations

Chemical structure and morphology of dorsal root ganglion neurons from naive and inflamed mice. (Barabas ME, Mattson EC, Aboualizadeh E, Hirschmugl CJ, Stucky CL) J Biol Chem 2014 Dec 05;289(49):34241-9 PMID: 25271163 PMCID: PMC4256355 SCOPUS ID: 2-s2.0-84917707294 10/02/2014 20 Citations

A novel mitochondrially-targeted apocynin derivative prevents hyposmia and loss of motor function in the leucine-rich repeat kinase 2 (LRRK2(R1441G)) transgenic mouse model of Parkinson's disease. (Dranka BP, Gifford A, McAllister D, Zielonka J, Joseph J, O'Hara CL, Stucky CL, Kanthasamy AG, Kalyanaraman B) Neurosci Lett 2014 Nov 07;583:159-64 PMID: 25263790 PMCID: PMC4253647 SCOPUS ID: 2-s2.0-84907997127 09/30/2014 36 Citations

Cold hypersensitivity increases with age in mice with sickle cell disease. (Zappia KJ, Garrison SR, Hillery CA, Stucky CL) Pain 2014 Dec;155(12):2476-2485 PMID: 24953902 PMCID: PMC4250326 SCOPUS ID: 2-s2.0-84922744582 06/24/2014 44 Citations

Contribution of transient receptor potential ankyrin 1 to chronic pain in aged mice with complete Freund's adjuvant-induced arthritis. (Garrison SR, Stucky CL) Arthritis Rheumatol 2014 Sep;66(9):2380-90 PMID: 24891324 PMCID: PMC4149259 SCOPUS ID: 2-s2.0-84907407432 06/04/2014 26 Citations

Piezo2 is required for Merkel-cell mechanotransduction. (Woo SH, Ranade S, Weyer AD, Dubin AE, Baba Y, Qiu Z, Petrus M, Miyamoto T, Reddy K, Lumpkin EA, Stucky CL, Patapoutian A) Nature 2014 May 29;509(7502):622-6 PMID: 24717433 PMCID: PMC4039622 SCOPUS ID: 2-s2.0-84901680112 04/11/2014 440 Citations

A gain-of-function voltage-gated sodium channel 1.8 mutation drives intense hyperexcitability of A- and C-fiber neurons. (Garrison SR, Weyer AD, Barabas ME, Beutler BA, Stucky CL) Pain 2014 May;155(5):896-905 PMID: 24447515 PMCID: PMC3989381 SCOPUS ID: 2-s2.0-84898597785 01/23/2014 29 Citations

Mechanical sensitization of cutaneous sensory fibers in the spared nerve injury mouse model. (Smith AK, O'Hara CL, Stucky CL) Mol Pain 2013 Nov 29;9:61 PMID: 24286165 PMCID: PMC3906996 SCOPUS ID: 2-s2.0-84888258179 11/30/2013 44 Citations

Opportunities for live cell FT-infrared imaging: macromolecule identification with 2D and 3D localization. (Mattson EC, Aboualizadeh E, Barabas ME, Stucky CL, Hirschmugl CJ) Int J Mol Sci 2013 Nov 19;14(11):22753-81 PMID: 24256815 PMCID: PMC3856089 SCOPUS ID: 2-s2.0-84887985788 11/22/2013 26 Citations

Spinal muscular atrophy astrocytes exhibit abnormal calcium regulation and reduced growth factor production. (McGivern JV, Patitucci TN, Nord JA, Barabas MA, Stucky CL, Ebert AD) Glia 2013 Sep;61(9):1418-1428 PMID: 23839956 PMCID: PMC3941074 SCOPUS ID: 2-s2.0-84880836806 07/11/2013 104 Citations

A 'toothache tree' alkylamide inhibits Aδ mechanonociceptors to alleviate mechanical pain. (Tsunozaki M, Lennertz RC, Vilceanu D, Katta S, Stucky CL, Bautista DM) J Physiol 2013 Jul 01;591(13):3325-40 PMID: 23652591 PMCID: PMC3717230 SCOPUS ID: 2-s2.0-84879845629 05/09/2013 52 Citations

TRPV1, but not TRPA1, in primary sensory neurons contributes to cutaneous incision-mediated hypersensitivity. (Barabas ME, Stucky CL) Mol Pain 2013 Mar 04;9:9 PMID: 23497345 PMCID: PMC3602024 SCOPUS ID: 2-s2.0-84874403769 03/19/2013 44 Citations

Failure of action potential propagation in sensory neurons: mechanisms and loss of afferent filtering in C-type units after painful nerve injury. (Gemes G, Koopmeiners A, Rigaud M, Lirk P, Sapunar D, Bangaru ML, Vilceanu D, Garrison SR, Ljubkovic M, Mueller SJ, Stucky CL, Hogan QH) J Physiol 2013 Feb 15;591(4):1111-31 PMID: 23148321 PMCID: PMC3591718 SCOPUS ID: 2-s2.0-84873713110 11/14/2012 62 Citations

TRPA1 is functionally expressed primarily by IB4-binding, non-peptidergic mouse and rat sensory neurons. (Barabas ME, Kossyreva EA, Stucky CL) PLoS One 2012;7(10):e47988 PMID: 23133534 PMCID: PMC3485059 SCOPUS ID: 2-s2.0-84868135050 11/08/2012 78 Citations

Patients with sickle cell disease have increased sensitivity to cold and heat. (Brandow AM, Stucky CL, Hillery CA, Hoffmann RG, Panepinto JA) Am J Hematol 2013 Jan;88(1):37-43 PMID: 23115062 PMCID: PMC3552380 SCOPUS ID: 2-s2.0-84871433814 11/02/2012 103 Citations

Prostaglandin metabolite induces inhibition of TRPA1 and channel-dependent nociception. (Weng Y, Batista-Schepman PA, Barabas ME, Harris EQ, Dinsmore TB, Kossyreva EA, Foshage AM, Wang MH, Schwab MJ, Wang VM, Stucky CL, Story GM) Mol Pain 2012 Sep 27;8:75 PMID: 23013719 PMCID: PMC3526547 SCOPUS ID: 2-s2.0-84866714578 09/28/2012 16 Citations

Sickle cell mice exhibit mechanical allodynia and enhanced responsiveness in light touch cutaneous mechanoreceptors. (Garrison SR, Kramer AA, Gerges NZ, Hillery CA, Stucky CL) Mol Pain 2012 Sep 10;8:62 PMID: 22963123 PMCID: PMC3495672 SCOPUS ID: 2-s2.0-84865847334 09/12/2012 40 Citations

TRPA1 mediates mechanical sensitization in nociceptors during inflammation. (Lennertz RC, Kossyreva EA, Smith AK, Stucky CL) PLoS One 2012;7(8):e43597 PMID: 22927999 PMCID: PMC3426543 SCOPUS ID: 2-s2.0-84865279306 08/29/2012 112 Citations

TRPC1 contributes to light-touch sensation and mechanical responses in low-threshold cutaneous sensory neurons. (Garrison SR, Dietrich A, Stucky CL) J Neurophysiol 2012 Feb;107(3):913-22 PMID: 22072513 PMCID: PMC3289471 SCOPUS ID: 2-s2.0-84855837580 11/11/2011 61 Citations

Transient receptor potential vanilloid 1 mediates pain in mice with severe sickle cell disease. (Hillery CA, Kerstein PC, Vilceanu D, Barabas ME, Retherford D, Brandow AM, Wandersee NJ, Stucky CL) Blood 2011 Sep 22;118(12):3376-83 PMID: 21708890 PMCID: PMC3179403 SCOPUS ID: 2-s2.0-80053217106 06/29/2011 108 Citations

Impaired sensory nerve function and axon morphology in mice with diabetic neuropathy. (Lennertz RC, Medler KA, Bain JL, Wright DE, Stucky CL) J Neurophysiol 2011 Aug;106(2):905-14 PMID: 21653724 PMCID: PMC3154824 SCOPUS ID: 2-s2.0-80051500527 06/10/2011 42 Citations

The dynamic TRPA1 channel: a suitable pharmacological pain target? (Garrison SR, Stucky CL) Curr Pharm Biotechnol 2011 Oct;12(10):1689-97 PMID: 21466445 PMCID: PMC3884818 SCOPUS ID: 2-s2.0-79959451143 04/07/2011 32 Citations

Mechanotransduction in the Nervous System (Bilston LE, Stucky CL) Studies in Mechanobiology, Tissue Engineering and Biomaterials 2011;3:231-245 SCOPUS ID: 2-s2.0-84956479834 01/01/2011 2 Citations

Pain tests provoke modality-specific cardiovascular responses in awake, unrestrained rats. (Rigaud M, Gemes G, Abram SE, Dean C, Hopp FA, Stucky CL, Eastwood D, Tarima S, Seagard J, Hogan QH) Pain 2011 Feb;152(2):274-284 PMID: 20943317 PMCID: PMC3022106 SCOPUS ID: 2-s2.0-78651511763 10/15/2010 12 Citations

TRPA1 mediates mechanical currents in the plasma membrane of mouse sensory neurons. (Vilceanu D, Stucky CL) PLoS One 2010 Aug 16;5(8):e12177 PMID: 20808441 PMCID: PMC2922334 SCOPUS ID: 2-s2.0-77957860650 09/03/2010 114 Citations

Physiological basis of tingling paresthesia evoked by hydroxy-alpha-sanshool. (Lennertz RC, Tsunozaki M, Bautista DM, Stucky CL) J Neurosci 2010 Mar 24;30(12):4353-61 PMID: 20335471 PMCID: PMC2852189 SCOPUS ID: 2-s2.0-77949834491 03/26/2010 67 Citations

Spinal nerve ligation in mouse upregulates TRPV1 heat function in injured IB4-positive nociceptors. (Vilceanu D, Honore P, Hogan QH, Stucky CL) J Pain 2010 Jun;11(6):588-99 PMID: 20015699 PMCID: PMC2879455 SCOPUS ID: 2-s2.0-77952742033 12/18/2009 44 Citations

Pharmacological blockade of TRPA1 inhibits mechanical firing in nociceptors. (Kerstein PC, del Camino D, Moran MM, Stucky CL) Mol Pain 2009 Apr 21;5:19 PMID: 19383149 PMCID: PMC2681449 SCOPUS ID: 2-s2.0-65649141656 04/23/2009 126 Citations

TRPA1 modulates mechanotransduction in cutaneous sensory neurons. (Kwan KY, Glazer JM, Corey DP, Rice FL, Stucky CL) J Neurosci 2009 Apr 15;29(15):4808-19 PMID: 19369549 PMCID: PMC2744291 SCOPUS ID: 2-s2.0-65549123596 04/17/2009 242 Citations

Roles of transient receptor potential channels in pain. (Stucky CL, Dubin AE, Jeske NA, Malin SA, McKemy DD, Story GM) Brain Res Rev 2009 Apr;60(1):2-23 PMID: 19203589 PMCID: PMC2683630 SCOPUS ID: 2-s2.0-63649152092 02/11/2009 147 Citations

Constitutive activity at the cannabinoid CB1 receptor is required for behavioral response to noxious chemical stimulation of TRPV1: antinociceptive actions of CB1 inverse agonists. (Fioravanti B, De Felice M, Stucky CL, Medler KA, Luo MC, Gardell LR, Ibrahim M, Malan TP Jr, Yamamura HI, Ossipov MH, King T, Lai J, Porreca F, Vanderah TW) J Neurosci 2008 Nov 05;28(45):11593-602 PMID: 18987195 PMCID: PMC2744288 SCOPUS ID: 2-s2.0-58149266680 11/07/2008 75 Citations

Neurotrophin-3 significantly reduces sodium channel expression linked to neuropathic pain states. (Wilson-Gerwing TD, Stucky CL, McComb GW, Verge VM) Exp Neurol 2008 Oct;213(2):303-14 PMID: 18601922 PMCID: PMC2751854 SCOPUS ID: 2-s2.0-51349109964 07/08/2008 35 Citations

Species and strain differences in rodent sciatic nerve anatomy: implications for studies of neuropathic pain. (Rigaud M, Gemes G, Barabas ME, Chernoff DI, Abram SE, Stucky CL, Hogan QH) Pain 2008 May;136(1-2):188-201 PMID: 18316160 PMCID: PMC2700063 SCOPUS ID: 2-s2.0-41749109317 03/05/2008 200 Citations

Stomatin and sensory neuron mechanotransduction. (Martinez-Salgado C, Benckendorff AG, Chiang LY, Wang R, Milenkovic N, Wetzel C, Hu J, Stucky CL, Parra MG, Mohandas N, Lewin GR) J Neurophysiol 2007 Dec;98(6):3802-8 PMID: 17942620 SCOPUS ID: 2-s2.0-37549027634 10/19/2007 40 Citations

Chemical interactions between fibrosarcoma cancer cells and sensory neurons contribute to cancer pain. (Khasabova IA, Stucky CL, Harding-Rose C, Eikmeier L, Beitz AJ, Coicou LG, Hanson AE, Simone DA, Seybold VS) J Neurosci 2007 Sep 19;27(38):10289-98 PMID: 17881535 PMCID: PMC6672679 SCOPUS ID: 2-s2.0-34548836298 09/21/2007 52 Citations

The menthol receptor TRPM8 is the principal detector of environmental cold. (Bautista DM, Siemens J, Glazer JM, Tsuruda PR, Basbaum AI, Stucky CL, Jordt SE, Julius D) Nature 2007 Jul 12;448(7150):204-8 PMID: 17538622 SCOPUS ID: 2-s2.0-34447542435 06/01/2007 944 Citations

Transgenic expression of a dominant-negative ASIC3 subunit leads to increased sensitivity to mechanical and inflammatory stimuli. (Mogil JS, Breese NM, Witty MF, Ritchie J, Rainville ML, Ase A, Abbadi N, Stucky CL, Séguéla P) J Neurosci 2005 Oct 26;25(43):9893-901 PMID: 16251436 PMCID: PMC6725570 SCOPUS ID: 2-s2.0-27344452734 10/28/2005 109 Citations

Painful nerve injury decreases resting cytosolic calcium concentrations in sensory neurons of rats. (Fuchs A, Lirk P, Stucky C, Abram SE, Hogan QH) Anesthesiology 2005 Jun;102(6):1217-25 PMID: 15915036 SCOPUS ID: 2-s2.0-19944403625 05/26/2005 48 Citations

Peripheral inflammation selectively increases TRPV1 function in IB4-positive sensory neurons from adult mouse. (Breese NM, George AC, Pauers LE, Stucky CL) Pain 2005 May;115(1-2):37-49 PMID: 15836968 SCOPUS ID: 2-s2.0-17044399313 04/20/2005 119 Citations

The P2Y agonist UTP activates cutaneous afferent fibers. (Stucky CL, Medler KA, Molliver DC) Pain 2004 May;109(1-2):36-44 PMID: 15082124 SCOPUS ID: 2-s2.0-1842685379 04/15/2004 64 Citations

Chronic hyperalgesia induced by repeated acid injections in muscle is abolished by the loss of ASIC3, but not ASIC1. (Sluka KA, Price MP, Breese NM, Stucky CL, Wemmie JA, Welsh MJ) Pain 2003 Dec;106(3):229-239 PMID: 14659506 SCOPUS ID: 2-s2.0-0344305593 12/09/2003 369 Citations

Differential response properties of IB(4)-positive and -negative unmyelinated sensory neurons to protons and capsaicin. (Dirajlal S, Pauers LE, Stucky CL) J Neurophysiol 2003 Jan;89(1):513-24 PMID: 12522198 SCOPUS ID: 2-s2.0-0037250805 01/11/2003 126 Citations

GFR alpha2/neurturin signalling regulates noxious heat transduction in isolectin B4-binding mouse sensory neurons. (Stucky CL, Rossi J, Airaksinen MS, Lewin GR) J Physiol 2002 Nov 15;545(1):43-50 PMID: 12433948 PMCID: PMC2290664 SCOPUS ID: 2-s2.0-1842869973 11/16/2002 50 Citations

Neurotrophin-4: a survival factor for adult sensory neurons. (Stucky CL, Shin JB, Lewin GR) Curr Biol 2002 Aug 20;12(16):1401-4 PMID: 12194821 SCOPUS ID: 2-s2.0-0037143446 08/27/2002 56 Citations

Erratum: The mammalian sodium channel BNC1 is required for normal touch sensation (Nature (2000) 407 (1007-1011)) (Price MP, Lewin GR, McIlwrath SL, Cheng C, Xie J, Heppenstall PA, Stucky CL, Mannsfeldt AG, Brennan TJ, Drummond HA, Qiao J, Benson CJ, Tarr DE, Hrstka RF, Yang B, Williamson RA, Walsh MJ) Nature 18 July 2002;418(6895):352 SCOPUS ID: 2-s2.0-0037130201 07/18/2002

The 5-HT3 subtype of serotonin receptor contributes to nociceptive processing via a novel subset of myelinated and unmyelinated nociceptors. (Zeitz KP, Guy N, Malmberg AB, Dirajlal S, Martin WJ, Sun L, Bonhaus DW, Stucky CL, Julius D, Basbaum AI) J Neurosci 2002 Feb 01;22(3):1010-9 PMID: 11826129 PMCID: PMC6758503 SCOPUS ID: 2-s2.0-0036462488 02/05/2002 314 Citations

Cannabinoid receptor agonists inhibit depolarization-induced calcium influx in cerebellar granule neurons. (Nogueron MI, Porgilsson B, Schneider WE, Stucky CL, Hillard CJ) J Neurochem 2001 Oct;79(2):371-81 PMID: 11677265 SCOPUS ID: 2-s2.0-0034775812 10/26/2001 39 Citations

Mechanisms of pain. (Stucky CL, Gold MS, Zhang X) Proc Natl Acad Sci U S A 2001 Oct 09;98(21):11845-6 PMID: 11562504 PMCID: PMC59728 SCOPUS ID: 2-s2.0-0035834013 09/20/2001 101 Citations

Neurotrophic factors meet nociceptor transduction: A sensational couple (Stucky CL) NeuroScience News 2001;4(3):42-49 SCOPUS ID: 2-s2.0-0035216983 01/01/2001 1 Citation

The mammalian sodium channel BNC1 is required for normal touch sensation. (Price MP, Lewin GR, McIlwrath SL, Cheng C, Xie J, Heppenstall PA, Stucky CL, Mannsfeldt AG, Brennan TJ, Drummond HA, Qiao J, Benson CJ, Tarr DE, Hrstka RF, Yang B, Williamson RA, Welsh MJ) Nature 2000 Oct 26;407(6807):1007-11 PMID: 11069180 SCOPUS ID: 2-s2.0-0034718899 11/09/2000 425 Citations

Hypoalgesia and altered inflammatory responses in mice lacking kinin B1 receptors. (Pesquero JB, Araujo RC, Heppenstall PA, Stucky CL, Silva JA Jr, Walther T, Oliveira SM, Pesquero JL, Paiva AC, Calixto JB, Lewin GR, Bader M) Proc Natl Acad Sci U S A 2000 Jul 05;97(14):8140-5 PMID: 10859349 PMCID: PMC16683 SCOPUS ID: 2-s2.0-0034608890 06/22/2000 327 Citations

Postnatal loss of Merkel cells, but not of slowly adapting mechanoreceptors in mice lacking the neurotrophin receptor p75. (Kinkelin I, Stucky CL, Koltzenburg M) Eur J Neurosci 1999 Nov;11(11):3963-9 PMID: 10583485 SCOPUS ID: 2-s2.0-0032726189 12/03/1999 43 Citations

Overexpression of nerve growth factor in skin selectively affects the survival and functional properties of nociceptors. (Stucky CL, Koltzenburg M, Schneider M, Engle MG, Albers KM, Davis BM) J Neurosci 1999 Oct 01;19(19):8509-16 PMID: 10493751 PMCID: PMC6783005 SCOPUS ID: 2-s2.0-0033216133 09/24/1999 99 Citations

Isolectin B(4)-positive and -negative nociceptors are functionally distinct. (Stucky CL, Lewin GR) J Neurosci 1999 Aug 01;19(15):6497-505 PMID: 10414978 PMCID: PMC6782829 SCOPUS ID: 2-s2.0-0033178342 07/22/1999 380 Citations

Stomatin, a MEC-2 like protein, is expressed by mammalian sensory neurons. (Mannsfeldt AG, Carroll P, Stucky CL, Lewin GR) Mol Cell Neurosci 1999 Jun;13(6):391-404 PMID: 10383825 SCOPUS ID: 2-s2.0-0032802786 06/29/1999 58 Citations

Point mutation in trkB causes loss of NT4-dependent neurons without major effects on diverse BDNF responses. (Minichiello L, Casagranda F, Tatche RS, Stucky CL, Postigo A, Lewin GR, Davies AM, Klein R) Neuron 1998 Aug;21(2):335-45 PMID: 9728915 SCOPUS ID: 2-s2.0-0032143555 09/05/1998 157 Citations

Neurotrophin 4 is required for the survival of a subclass of hair follicle receptors. (Stucky CL, DeChiara T, Lindsay RM, Yancopoulos GD, Koltzenburg M) J Neurosci 1998 Sep 01;18(17):7040-6 PMID: 9712673 PMCID: PMC6792951 SCOPUS ID: 2-s2.0-0032171392 08/26/1998 67 Citations

Bradykinin increases the proportion of neonatal rat dorsal root ganglion neurons that respond to capsaicin and protons. (Stucky CL, Abrahams LG, Seybold VS) Neuroscience 1998 Jun;84(4):1257-65 PMID: 9578411 SCOPUS ID: 2-s2.0-0031981906 05/13/1998 38 Citations

Receptive properties of mouse sensory neurons innervating hairy skin. (Koltzenburg M, Stucky CL, Lewin GR) J Neurophysiol 1997 Oct;78(4):1841-50 PMID: 9325353 SCOPUS ID: 2-s2.0-0030821372 10/27/1997 282 Citations

The low-affinity neurotrophin receptor p75 regulates the function but not the selective survival of specific subpopulations of sensory neurons. (Stucky CL, Koltzenburg M) J Neurosci 1997 Jun 01;17(11):4398-405 PMID: 9151756 PMCID: PMC6573523 SCOPUS ID: 2-s2.0-0030979272 06/01/1997 61 Citations

Prostaglandin E2 increases the proportion of neonatal rat dorsal root ganglion neurons that respond to bradykinin. (Stucky CL, Thayer SA, Seybold VS) Neuroscience 1996 Oct;74(4):1111-23 PMID: 8895879 SCOPUS ID: 2-s2.0-0030254111 10/01/1996 35 Citations

Time-dependent changes in Bolton-Hunter-labeled 125I-substance P binding in rat spinal cord following unilateral adjuvant-induced peripheral inflammation. (Stucky CL, Galeazza MT, Seybold VS) Neuroscience 1993 Nov;57(2):397-409 PMID: 7509468 SCOPUS ID: 2-s2.0-0027366544 11/01/1993 43 Citations

Changes in [125I]hCGRP binding in rat spinal cord in an experimental model of acute, peripheral inflammation. (Galeazza MT, Stucky CL, Seybold VS) Brain Res 1992 Sep 25;591(2):198-208 PMID: 1332803 SCOPUS ID: 2-s2.0-0026616801 09/25/1992 20 Citations

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Profiles for MCW, MU, MSOE, UWM, BCW, CW, Froedtert, and VA Faculty

Cheryl L. Stucky PhD

Professor

Publications (113)