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Ehab A. Abourashed PhD

Ehab A. Abourashed PhD profile photo picture

Professor

Institution: Medical College of Wisconsin
Department: School of Pharmacy Administration
Division: Administration
Program: Program Development


Research Experience

  • Anti-Bacterial Agents
  • Antioxidants
  • Benzoquinones
  • Biotransformation
  • Chromatography, High Pressure Liquid
  • Dietary Supplements
  • Isoflavones
  • Magnetic Resonance Spectroscopy
  • Microbial Sensitivity Tests
  • Molecular Structure
  • Phytotherapy
  • Plant Extracts
  • Plants, Medicinal
  • Quality Control
  • Sesquiterpenes
  • Methodologies and Techniques

  • Antioxidants
  • Biotransformation
  • Chromatography, High Pressure Liquid
  • Dietary Supplements
  • Gas Chromatography-Mass Spectrometry
  • Magnetic Resonance Spectroscopy
  • Molecular Structure
  • Phytotherapy
  • Plant Extracts
  • Plants, Medicinal
  • Quality Control
  • Spectrophotometry, Infrared
  • Spectroscopy, Fourier Transform Infrared
  • Tandem Mass Spectrometry
  • Leadership Positions

  • Chair, Curriculum Committee, School of Pharmacy, 2017-present
  • Educational Expertise

  • Anti-Bacterial Agents
  • Antioxidants
  • Chromatography, High Pressure Liquid
  • Dietary Supplements
  • Magnetic Resonance Spectroscopy
  • Microbial Sensitivity Tests
  • Molecular Structure
  • Phytotherapy
  • Plant Extracts
  • Plants, Medicinal
  • Publications (61)

  • Retained strength of expired albuterol and montelukast pharmaceuticals (Abourashed EA, Kutty RG, Bevry M, Hoffmann P) Annals of Allergy, Asthma and Immunology February 2022;128(2):222-223 SCOPUS ID: 2-s2.0-85118702838 02/01/2022       1 Citation
  • Stability Determination of an Extemporaneously Compounded Ambrisentan Suspension by High Performance Liquid Chromatography Analysis. (Cramer J, Bevry M, Handler S, Tillman K, Abourashed EA) J Pediatr Pharmacol Ther 2021;26(3):265-270 PMID: 33833628 PMCID: PMC8021248 SCOPUS ID: 2-s2.0-85104684194 04/10/2021    
  • Phenolic compounds from nutmeg (Myristica fragrans Houtt.) inhibit the endocannabinoid-modulating enzyme fatty acid amide hydrolase. (El-Alfy AT, Abourashed EA, Patel C, Mazhari N, An H, Jeon A) J Pharm Pharmacol 2019 Dec;71(12):1879-1889 PMID: 31595522 PMCID: PMC7938946 SCOPUS ID: 2-s2.0-85074090803 10/09/2019       9 Citations
  • A sustained elective course on substance abuse and addiction delivered in an academic pharmacy programme (Abourashed EA, Cross W) Pharmacy Education 2019;19(1):190-198 SCOPUS ID: 2-s2.0-85070471715 01/01/2019    
  • Review of Stilbenes: Applications in Chemistry, Life Sciences and Materials Science (Abourashed EA) Journal of Natural Products 24 February 2017;80(2):577 SCOPUS ID: 2-s2.0-85013857798 02/24/2017       5 Citations
  • Review of Stilbenes: Applications in Chemistry, Life Sciences and Materials Science Stilbenes: Applications in Chemistry, Life Sciences and Materials Science . By Gertz Likhtenshtein. Wiley-VCH , Weinheim, Germany . 2009 . 360 pp. $224 Hardcover. ISBN 978-3-527-32388-3 . (Abourashed EA) J Nat Prod 2017 Feb 24;80(2):577 PMID: 28191947 02/14/2017    
  • Hydroxybenzoic Acids Are Significant Contributors to the Antioxidant Effect of Borututu Bark, Cochlospermum angolensis Welw. ex Oliv. (Abourashed EA, Fu HW) Antioxidants (Basel) 2017 Jan 28;6(1) PMID: 28134834 PMCID: PMC5384172 SCOPUS ID: 2-s2.0-85012045844 01/31/2017       3 Citations
  • Chemical diversity and pharmacological significance of the secondary metabolites of nutmeg (Myristica fragrans Houtt.). (Abourashed EA, El-Alfy AT) Phytochem Rev 2016 Dec;15(6):1035-1056 PMID: 28082856 PMCID: PMC5222521 SCOPUS ID: 2-s2.0-84966525966 01/14/2017       55 Citations
  • HPLC-Guided Isolation, Purification and Characterization of Phenylpropanoid and Phenolic Constituents of Nutmeg Kernel (Myristica fragrans). (Chiu S, Wang T, Belski M, Abourashed EA) Nat Prod Commun 2016 Apr;11(4):483-8 PMID: 27396199 PMCID: PMC4943679 SCOPUS ID: 2-s2.0-85016745170 07/12/2016       16 Citations
  • Indirect modulation of the endocannabinoid system by specific fractions of nutmeg total extract. (El-Alfy AT, Joseph S, Brahmbhatt A, Akati S, Abourashed EA) Pharm Biol 2016 Dec;54(12):2933-2938 PMID: 27296774 SCOPUS ID: 2-s2.0-84974800846 06/15/2016       5 Citations
  • Potential of Horse Apple Isoflavones in Targeting Inflammation and Tau Protein Fibrillization. (Abourashed EA, Abraha A, Khan SI, McCants T, Awan S) Nat Prod Commun 2015 Sep;10(9):1577-80 PMID: 26594763 SCOPUS ID: 2-s2.0-84954624058 11/26/2015       3 Citations
  • Recently disclosed chemical entities as potential candidates for management of tuberculosis. (Stec J, Abourashed EA) Pharm Pat Anal 2015;4(4):317-47 PMID: 26174569 SCOPUS ID: 2-s2.0-85050578152 07/16/2015       2 Citations
  • Evaluation of cost versus antioxidant determinants in green tea dietary supplements. (A Roberson CL, Abourashed EA, Elsharkawy N) J Am Pharm Assoc (2003) 2015 Jul-Aug;55(4):381-9 PMID: 26070074 SCOPUS ID: 2-s2.0-84936934619 06/13/2015       2 Citations
  • Synthesis and in vitro evaluation of ferutinol aryl esters for estrogenic activity and affinity toward cannabinoid receptors (Osman AMG, Abourashed EA, Slade D, Ahmed SA, Gul W, Khan SI, Elfadl TA, Dale OR, Husni AS, Cutler SJ, Elsohly MA) Medicinal Chemistry Research 11 June 2015;24(6):2670-2678 SCOPUS ID: 2-s2.0-84930929150 06/11/2015       3 Citations
  • Synthesis and in Vitro Evaluation of Ferutinol Aryl Esters for Estrogenic Activity and their Affinity (A.M.G. Osman E.A. Abourashe D. Slade S.A. Ahmed W. Gul S.I. Khan T. Abo-Elfadl O.R. Dale A.S. Husni S.J. Cutler M.A. ElSohly) Med. Chem. Res. Osman, A.M.G., Abourashed, E.A., Slade, D. et al. Med Chem Res (2015) 24: 2670. doi:10.1007/s00044-015-1319-7 06/01/2015    
  • Content Variation of Catechin Markers, Total Phenolics and Caffeine in Green Tea Dietary Supplements. (Abourashed EA, Roberson CL, Elsharkawy N) J Diet Suppl 2016;13(2):171-84 PMID: 25299974 SCOPUS ID: 2-s2.0-84947047434 10/10/2014       10 Citations
  • HPLC determination of isoflavone levels in osage orange from the Midwest and southern United States. (Darji K, Miglis C, Wardlow A, Abourashed EA) J Agric Food Chem 2013 Jul 17;61(28):6806-11 PMID: 23772950 PMCID: PMC3774050 SCOPUS ID: 2-s2.0-84880359224 06/19/2013       11 Citations
  • Bioavailability of Plant-Derived Antioxidants. (Abourashed EA) Antioxidants (Basel) 2013 Nov 05;2(4):309-25 PMID: 26784467 PMCID: PMC4665521 SCOPUS ID: 2-s2.0-84942745017 01/01/2013       51 Citations
  • Bioconversion of silybin to phase I and II microbial metabolites with retained antioxidant activity. (Abourashed EA, Mikell JR, Khan IA) Bioorg Med Chem 2012 May 01;20(9):2784-8 PMID: 22503365 SCOPUS ID: 2-s2.0-84859891632 04/17/2012       31 Citations
  • Nature against depression. (El-Alfy AT, Abourashed EA, Matsumoto RR) Curr Med Chem 2012;19(14):2229-41 PMID: 22414105 SCOPUS ID: 2-s2.0-84860661296 03/15/2012       16 Citations
  • Antimycobacterial activity of ferutinin alone and in combination with antitubercular drugs against a rapidly growing surrogate of Mycobacterium tuberculosis. (Abourashed EA, Galal AM, Shibl AM) Nat Prod Res 2011 Jul;25(12):1142-9 PMID: 21442547 SCOPUS ID: 2-s2.0-79960483919 03/29/2011       10 Citations
  • Liquid chromatographic high-throughput analysis of the new ultra-short acting hypnotic 'HIE-124' and its metabolite in mice serum using a monolithic silica column (Kadi A, Hefnawy M, Al-Majed A, Alonezi S, Asiri Y, Attia S, Abourashed E, El-Subbagh H) Analyst 7 February 2011;136(3):591-597 SCOPUS ID: 2-s2.0-78751542884 02/07/2011       10 Citations
  • Novel, selective sample stacking microemulsion electrokinetic capillary chromatography induced by reverse migrating pseudostationary phase for the determination of the new ultra-short acting hypnotic "HIE-124" in mice serum. (Hefnawy M, Al-Omar M, Julkhuf S, Attia S, Abourashed E, El-Subbagh H) Anal Chim Acta 2010 Jul 19;673(2):194-9 PMID: 20599035 SCOPUS ID: 2-s2.0-77954219288 07/06/2010       14 Citations
  • Towards a better understanding of the psychopharmacology of nutmeg: Activities in the mouse tetrad assay. (El-Alfy AT, Wilson L, ElSohly MA, Abourashed EA) J Ethnopharmacol 2009 Nov 12;126(2):280-6 PMID: 19703539 PMCID: PMC2783227 SCOPUS ID: 2-s2.0-70350346860 08/26/2009       26 Citations
  • HPTLC analysis of a new ultra-short-acting thiazolodiazepine hypnotic (HIE-124) in spiked human plasma (Abourashed E, Hefnawy M, El-Subbagh H) Journal of Planar Chromatography - Modern TLC 1 June 2009;22(3):183-186 SCOPUS ID: 2-s2.0-67650651970 06/01/2009       4 Citations
  • Chemical composition and biological evaluation of the essential oil of Commiphora opobalsamum L. (Al-Massarany SM, Abbas FA, Demirci B, Baser KHC, Khan SI, Al-Rehaily AJ, Mossa JS, Abourashed EA) Journal of Herbs, Spices and Medicinal Plants 28 April 2008;13(4):111-121 SCOPUS ID: 2-s2.0-67650269887 04/28/2008       7 Citations
  • Enhancing effect of isoeugenol on the antimicrobial activity of isoniazid, 6-paradol and 6-shogaol (Abourashed EA, Galal AM, Shebl AM, Mossa JS) Journal of Herbs, Spices and Medicinal Plants 28 April 2008;13(4):95-103 SCOPUS ID: 2-s2.0-67650257681 04/28/2008       8 Citations
  • Phytochemical and biological studies on Saudi Commiphora opobalsamum L. (Abbas FA, Al-Massarany SM, Khan S, Al-Howiriny TA, Mossa JS, Abourashed EA) Nat Prod Res 2007 May;21(5):383-91 PMID: 17487607 SCOPUS ID: 2-s2.0-34548545051 05/10/2007       51 Citations
  • HPTLC determination of sildenafil in pharmaceutical products and aphrodisiac herbal preparations (Abourashed EA, Abdel-Kader MS, Habib AAM) Journal of Planar Chromatography - Modern TLC September 2005;18(105):372-376 SCOPUS ID: 2-s2.0-27944450125 09/01/2005       21 Citations
  • In vitro binding experiments with a Valerian, hops and their fixed combination extract (Ze91019) to selected central nervous system receptors. (Abourashed EA, Koetter U, Brattstr??m A) Phytomedicine 2004 Nov;11(7-8):633-8 PMID: 15636177 SCOPUS ID: 2-s2.0-10844275745 01/08/2005       76 Citations
  • Thin-layer densitometry as an alternative tool in the quantitative evaluation of the free radical scavenging activity of natural antioxidants (Abourashed EA) Zeitschrift fur Naturforschung - Section B Journal of Chemical Sciences November 2005;60(11):1212-1218 SCOPUS ID: 2-s2.0-29944443816 01/01/2005       8 Citations
  • HPTLC determination of caffeine in stimulant herbal products and power drinks. (Abourashed EA, Mossa JS) J Pharm Biomed Anal 2004 Nov 15;36(3):617-20 PMID: 15522538 SCOPUS ID: 2-s2.0-7444262420 11/04/2004       48 Citations
  • Lotaustralin from Rhodiola rosea roots. (Akgul Y, Ferreira D, Abourashed EA, Khan IA) Fitoterapia 2004 Sep;75(6):612-4 PMID: 15351122 SCOPUS ID: 2-s2.0-4444234632 09/08/2004       30 Citations
  • Validation and application of an HPTLC method for the determination of parthenolide in feverfew herbal products (Abourashed EA) Journal of Planar Chromatography - Modern TLC September 2004;17(5):375-378 SCOPUS ID: 2-s2.0-9744246873 09/01/2004       7 Citations
  • The fixed combination of valerian and hops (Ze91019) acts via a central adenosine mechanism. (Schellenberg R, Sauer S, Abourashed EA, Koetter U, Brattstr??m A) Planta Med 2004 Jul;70(7):594-7 PMID: 15254851 SCOPUS ID: 2-s2.0-3543004166 07/16/2004       43 Citations
  • Transport of harman alkaloids across Caco-2 cell monolayers. (Khan SI, Abourashed EA, Khan IA, Walker LA) Chem Pharm Bull (Tokyo) 2004 Apr;52(4):394-7 PMID: 15056950 SCOPUS ID: 2-s2.0-7444267875 04/02/2004       22 Citations
  • Transport of parthenolide across human intestinal cells (Caco-2). (Khan SI, Abourashed EA, Khan IA, Walker LA) Planta Med 2003 Nov;69(11):1009-12 PMID: 14735438 SCOPUS ID: 2-s2.0-0346689998 01/22/2004       29 Citations
  • Ephedra in perspective--a current review. (Abourashed EA, El-Alfy AT, Khan IA, Walker L) Phytother Res 2003 Aug;17(7):703-12 PMID: 12916063 SCOPUS ID: 2-s2.0-0041976090 08/14/2003       183 Citations
  • HPLC fingerprinting and estimation of the bioactive components of Clutia richardiana L. as a potential hypoglycemic herbal tea. (Abourashed EA, Ganzera M, Khan IA, Khan S, Mossa JS, El-Feraly FS) Phytother Res 2003 Jun;17(6):657-60 PMID: 12820235 SCOPUS ID: 2-s2.0-0038802399 06/24/2003       14 Citations
  • High-speed extraction and HPLC fingerprinting of medicinal plants - II. Application to harman alkaloids of genus Passiflora (Abourashed EA, Vanderplank J, Khan IA) Pharmaceutical Biology April 2003;41(2):100-106 SCOPUS ID: 2-s2.0-0038798417 04/01/2003       23 Citations
  • High-Speed Extraction and HPLC Fingerprinting of Medicinal Plants a?? II. Application to Harman Alkaloids of Genus Passiflora (E.A. Abourashed J. Vanderplank I.A. Khan) Pharm. Biol. 2003, 41, 100-106. http://dx.doi.org/10.1076/phbi.41.2.100.14244 03/01/2003    
  • Clinic at the health food store? Employee recommendations and product analysis. (Glisson JK, Rogers HE, Abourashed EA, Ogletree R, Hufford CD, Khan I) Pharmacotherapy 2003 Jan;23(1):64-72 PMID: 12523461 SCOPUS ID: 2-s2.0-0037226603 01/14/2003       33 Citations
  • Interactions of valerian extracts and a fixed valerian-hop extract combination with adenosine receptors. (M??ller CE, Schumacher B, Brattstr??m A, Abourashed EA, Koetter U) Life Sci 2002 Sep 06;71(16):1939-49 PMID: 12175708 SCOPUS ID: 2-s2.0-0037031791 08/15/2002       75 Citations
  • High-speed extraction and HPLC fingerprinting of medicinal plants - I. Application to Passiflora flavonoids (Abourashed EA, Vanderplank JR, Khan IA) Pharmaceutical Biology 2002;40(2):81-91 SCOPUS ID: 2-s2.0-0036063892 07/24/2002       39 Citations
  • The inhibitory activity of natural products on plant p-hydroxyphenylpyruvate dioxygenase. (Meazza G, Scheffler BE, Tellez MR, Rimando AM, Romagni JG, Duke SO, Nanayakkara D, Khan IA, Abourashed EA, Dayan FE) Phytochemistry 2002 Jun;60(3):281-8 PMID: 12031447 SCOPUS ID: 2-s2.0-0037030803 05/29/2002       147 Citations
  • High-Speed Extraction and HPLC Fingerprinting of Medicinal Plants a?? I. Application to Passiflora Flavonoids (E.A. Abourashed J.R. Vanderplank I.A. Khan. ) Pharm. Biol. Pharm. Biol., 2002, 40, 81-91. i??http://dx.doi.org/10.1076/phbi.40.2.81.5844 03/01/2002    
  • GC determination of parthenolide in feverfew products. (Abourashed EA, Khan IA) Pharmazie 2001 Dec;56(12):971-2 PMID: 11802663 SCOPUS ID: 2-s2.0-0035666370 01/23/2002       6 Citations
  • Separation and quantification of the major daucane esters of Ferula hermonis by HPLC. (Abourashed EA, Galal AM, El-Feraly FS, Khan IA) Planta Med 2001 Oct;67(7):681-2 PMID: 11582552 SCOPUS ID: 2-s2.0-0034813877 10/03/2001       28 Citations
  • Inhibitory effects of maesanin and analogs on arachidonic acid metabolizing enzymes. (Abourashed EA, Muhammad I, Resch M, Bauer R, el-Feraly FS, Hufford CD) Planta Med 2001 Jun;67(4):360-1 PMID: 11458456 SCOPUS ID: 2-s2.0-0034955366 07/19/2001       9 Citations
  • High-performance liquid chromatography determination of hydrastine and berberine in dietary supplements containing goldenseal. (Abourashed EA, Khan IA) J Pharm Sci 2001 Jul;90(7):817-22 PMID: 11458331 SCOPUS ID: 2-s2.0-0034938508 07/18/2001       55 Citations
  • Determination of heavy metals and pesticides in ginseng products. (Khan IA, Allgood J, Walker LA, Abourashed EA, Schlenk D, Benson WH) J AOAC Int 2001 May-Jun;84(3):936-9 PMID: 11417656 SCOPUS ID: 2-s2.0-0035344907 06/22/2001       81 Citations
  • Daucane sesquiterpenes from Ferula hermonis. (Galal AM, Abourashed EA, Ross SA, ElSohly MA, Al-Said MS, El-Feraly FS) J Nat Prod 2001 Mar;64(3):399-400 PMID: 11277769 SCOPUS ID: 2-s2.0-0035091149 03/30/2001       47 Citations
  • Microbial transformation of kawain and methysticin. (Abourashed EA, Khan IA) Chem Pharm Bull (Tokyo) 2000 Dec;48(12):1996-8 PMID: 11145158 SCOPUS ID: 2-s2.0-0034536068 01/06/2001       24 Citations
  • Determination of parthenolide in selected feverfew products by liquid chromatography. (Abourashed EA, Khan IA, Abourashed EA, Khan IA) J AOAC Int 2000 Jul-Aug;83(4):789-92 PMID: 10995104 SCOPUS ID: 2-s2.0-0034219691 09/20/2000       17 Citations
  • 2-Hydroxy-5-(ethanolamino)-3-(10'-Z-pentadecenyl)-1,4-benzoquinone, new microbial phase II metabolite of maesanin. (Abourashed EA, el-Feraly FS, Khan IA, Hufford CD) Chem Pharm Bull (Tokyo) 2000 Jan;48(1):45-7 PMID: 10705473 SCOPUS ID: 2-s2.0-0033978179 03/08/2000       4 Citations
  • Carboxylic acid microbial metabolites of the natural benzoquinone, maesanin (Abourashed EA, El-Feraly FS, Hufford CD) J Nat Prod 1999 Oct;62(10):1474 PMID: 10545055 SCOPUS ID: 2-s2.0-0032747152 11/02/1999    
  • Two new flavone glycosides from paullinia pinnata (Abourashed EA, Toyang NJ, Choinski J Jr, Khan IA) J Nat Prod 1999 Aug;62(8):1179-81 PMID: 10479333 SCOPUS ID: 2-s2.0-0032822894 09/10/1999       36 Citations
  • Carboxylic acid microbial metabolites of the natural benzoquinone, maesanin (Abourashed EA, El-Feraly FS, Hufford CD) J Nat Prod 1999 May;62(5):714-6 PMID: 10346952 SCOPUS ID: 2-s2.0-0033000781 05/29/1999       6 Citations
  • Microbial models of mammalian metabolism of xenobiotics: An updated review. (Abourashed EA, Clark AM, Hufford CD) Curr Med Chem 1999 May;6(5):359-74 PMID: 10101217 SCOPUS ID: 2-s2.0-0032895172 04/02/1999       104 Citations
  • Microbial Transformation of Artemether (E.A. Abourashed C.D. Hufford) J. Nat. Prod. J. Nat. Prod., 1996, 59 (3), pp 251a??253 03/22/1996    
  • Microbial transformation of artemether (Abourashed EA, Hufford CD) Journal of Natural Products March 1996;59(3):251-253 SCOPUS ID: 2-s2.0-0030000413 03/01/1996       26 Citations
  • Last update: 12/10/2021