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Ehab A. Abourashed PhD

Ehab A. Abourashed PhD profile photo picture

Professor

Institution: Medical College of Wisconsin
Department: School of Pharmacy Administration
Division: Administration
Program: Program Development


Research Experience

  • Anti-Bacterial Agents
  • Antioxidants
  • Benzoquinones
  • Biotransformation
  • Chromatography, High Pressure Liquid
  • Dietary Supplements
  • Isoflavones
  • Magnetic Resonance Spectroscopy
  • Microbial Sensitivity Tests
  • Molecular Structure
  • Phytotherapy
  • Plant Extracts
  • Plants, Medicinal
  • Quality Control
  • Sesquiterpenes
  • Methodologies and Techniques

  • Antioxidants
  • Biotransformation
  • Chromatography, High Pressure Liquid
  • Dietary Supplements
  • Gas Chromatography-Mass Spectrometry
  • Magnetic Resonance Spectroscopy
  • Molecular Structure
  • Phytotherapy
  • Plant Extracts
  • Plants, Medicinal
  • Quality Control
  • Spectrophotometry, Infrared
  • Spectroscopy, Fourier Transform Infrared
  • Tandem Mass Spectrometry
  • Leadership Positions

  • Chair, Curriculum Committee, School of Pharmacy, 2017-present
  • Educational Expertise

  • Anti-Bacterial Agents
  • Antioxidants
  • Chromatography, High Pressure Liquid
  • Dietary Supplements
  • Magnetic Resonance Spectroscopy
  • Microbial Sensitivity Tests
  • Molecular Structure
  • Phytotherapy
  • Plant Extracts
  • Plants, Medicinal
  • Publications (45)

  • Phenolic compounds from nutmeg (Myristica fragrans Houtt.) inhibit the endocannabinoid-modulating enzyme fatty acid amide hydrolase. (El-Alfy AT, Abourashed EA, Patel C, Mazhari N, An H, Jeon A) J Pharm Pharmacol 2019 Dec;71(12):1879-1889 PMID: 31595522 PMCID: PMC7938946 10/09/2019       5 Citations
  • Review of Stilbenes: Applications in Chemistry, Life Sciences and Materials Science Stilbenes: Applications in Chemistry, Life Sciences and Materials Science . By Gertz Likhtenshtein. Wiley-VCH , Weinheim, Germany . 2009 . 360 pp. $224 Hardcover. ISBN 978-3-527-32388-3 . (Abourashed EA) J Nat Prod 2017 Feb 24;80(2):577 PMID: 28191947 02/14/2017    
  • Hydroxybenzoic Acids Are Significant Contributors to the Antioxidant Effect of Borututu Bark, Cochlospermum angolensis Welw. ex Oliv. (Abourashed EA, Fu HW) Antioxidants (Basel) 2017 Jan 28;6(1) PMID: 28134834 PMCID: PMC5384172 01/31/2017    
  • Chemical diversity and pharmacological significance of the secondary metabolites of nutmeg (Myristica fragrans Houtt.). (Abourashed EA, El-Alfy AT) Phytochem Rev 2016 Dec;15(6):1035-1056 PMID: 28082856 PMCID: PMC5222521 01/14/2017    
  • HPLC-Guided Isolation, Purification and Characterization of Phenylpropanoid and Phenolic Constituents of Nutmeg Kernel (Myristica fragrans). (Chiu S, Wang T, Belski M, Abourashed EA) Nat Prod Commun 2016 Apr;11(4):483-8 PMID: 27396199 PMCID: PMC4943679 07/12/2016       9 Citations
  • Indirect modulation of the endocannabinoid system by specific fractions of nutmeg total extract. (El-Alfy AT, Joseph S, Brahmbhatt A, Akati S, Abourashed EA) Pharm Biol 2016 Dec;54(12):2933-2938 PMID: 27296774 06/15/2016       4 Citations
  • Potential of Horse Apple Isoflavones in Targeting Inflammation and Tau Protein Fibrillization. (Abourashed EA, Abraha A, Khan SI, McCants T, Awan S) Nat Prod Commun 2015 Sep;10(9):1577-80 PMID: 26594763 11/26/2015       1 Citation
  • Recently disclosed chemical entities as potential candidates for management of tuberculosis. (Stec J, Abourashed EA) Pharm Pat Anal 2015;4(4):317-47 PMID: 26174569 07/16/2015       2 Citations
  • Evaluation of cost versus antioxidant determinants in green tea dietary supplements. (A Roberson CL, Abourashed EA, Elsharkawy N) J Am Pharm Assoc (2003) 2015 Jul-Aug;55(4):381-9 PMID: 26070074 06/13/2015       2 Citations
  • Synthesis and in Vitro Evaluation of Ferutinol Aryl Esters for Estrogenic Activity and their Affinity (A.M.G. Osman E.A. Abourashe D. Slade S.A. Ahmed W. Gul S.I. Khan T. Abo-Elfadl O.R. Dale A.S. Husni S.J. Cutler M.A. ElSohly) Med. Chem. Res. Osman, A.M.G., Abourashed, E.A., Slade, D. et al. Med Chem Res (2015) 24: 2670. doi:10.1007/s00044-015-1319-7 06/01/2015    
  • Content Variation of Catechin Markers, Total Phenolics and Caffeine in Green Tea Dietary Supplements. (Abourashed EA, Roberson CL, Elsharkawy N) J Diet Suppl 2016;13(2):171-84 PMID: 25299974 10/10/2014       7 Citations
  • HPLC determination of isoflavone levels in osage orange from the Midwest and southern United States. (Darji K, Miglis C, Wardlow A, Abourashed EA) J Agric Food Chem 2013 Jul 17;61(28):6806-11 PMID: 23772950 PMCID: PMC3774050 06/19/2013       9 Citations
  • Bioavailability of Plant-Derived Antioxidants. (Abourashed EA) Antioxidants (Basel) 2013 Nov 05;2(4):309-25 PMID: 26784467 PMCID: PMC4665521 01/01/2013    
  • Bioconversion of silybin to phase I and II microbial metabolites with retained antioxidant activity. (Abourashed EA, Mikell JR, Khan IA) Bioorg Med Chem 2012 May 01;20(9):2784-8 PMID: 22503365 04/17/2012       27 Citations
  • Nature against depression. (El-Alfy AT, Abourashed EA, Matsumoto RR) Curr Med Chem 2012;19(14):2229-41 PMID: 22414105 03/15/2012       14 Citations
  • Antimycobacterial activity of ferutinin alone and in combination with antitubercular drugs against a rapidly growing surrogate of Mycobacterium tuberculosis. (Abourashed EA, Galal AM, Shibl AM) Nat Prod Res 2011 Jul;25(12):1142-9 PMID: 21442547 03/29/2011       10 Citations
  • Towards a better understanding of the psychopharmacology of nutmeg: Activities in the mouse tetrad assay. (El-Alfy AT, Wilson L, ElSohly MA, Abourashed EA) J Ethnopharmacol 2009 Nov 12;126(2):280-6 PMID: 19703539 PMCID: PMC2783227 08/26/2009       21 Citations
  • Phytochemical and biological studies on Saudi Commiphora opobalsamum L. (Abbas FA, Al-Massarany SM, Khan S, Al-Howiriny TA, Mossa JS, Abourashed EA) Nat Prod Res 2007 May;21(5):383-91 PMID: 17487607 05/10/2007       44 Citations
  • In vitro binding experiments with a Valerian, hops and their fixed combination extract (Ze91019) to selected central nervous system receptors. (Abourashed EA, Koetter U, Brattström A) Phytomedicine 2004 Nov;11(7-8):633-8 PMID: 15636177 01/08/2005       71 Citations
  • HPTLC determination of caffeine in stimulant herbal products and power drinks. (Abourashed EA, Mossa JS) J Pharm Biomed Anal 2004 Nov 15;36(3):617-20 PMID: 15522538 11/04/2004       44 Citations
  • Lotaustralin from Rhodiola rosea roots. (Akgul Y, Ferreira D, Abourashed EA, Khan IA) Fitoterapia 2004 Sep;75(6):612-4 PMID: 15351122 09/08/2004       28 Citations
  • The fixed combination of valerian and hops (Ze91019) acts via a central adenosine mechanism. (Schellenberg R, Sauer S, Abourashed EA, Koetter U, Brattström A) Planta Med 2004 Jul;70(7):594-7 PMID: 15254851 07/16/2004       40 Citations
  • Transport of harman alkaloids across Caco-2 cell monolayers. (Khan SI, Abourashed EA, Khan IA, Walker LA) Chem Pharm Bull (Tokyo) 2004 Apr;52(4):394-7 PMID: 15056950 04/02/2004       20 Citations
  • Transport of parthenolide across human intestinal cells (Caco-2). (Khan SI, Abourashed EA, Khan IA, Walker LA) Planta Med 2003 Nov;69(11):1009-12 PMID: 14735438 01/22/2004       28 Citations
  • Ephedra in perspective--a current review. (Abourashed EA, El-Alfy AT, Khan IA, Walker L) Phytother Res 2003 Aug;17(7):703-12 PMID: 12916063 08/14/2003       161 Citations
  • HPLC fingerprinting and estimation of the bioactive components of Clutia richardiana L. as a potential hypoglycemic herbal tea. (Abourashed EA, Ganzera M, Khan IA, Khan S, Mossa JS, El-Feraly FS) Phytother Res 2003 Jun;17(6):657-60 PMID: 12820235 06/24/2003       13 Citations
  • High-Speed Extraction and HPLC Fingerprinting of Medicinal Plants – II. Application to Harman Alkaloids of Genus Passiflora (E.A. Abourashed J. Vanderplank I.A. Khan) Pharm. Biol. 2003, 41, 100-106. http://dx.doi.org/10.1076/phbi.41.2.100.14244 03/01/2003    
  • Clinic at the health food store? Employee recommendations and product analysis. (Glisson JK, Rogers HE, Abourashed EA, Ogletree R, Hufford CD, Khan I) Pharmacotherapy 2003 Jan;23(1):64-72 PMID: 12523461 01/14/2003       32 Citations
  • Interactions of valerian extracts and a fixed valerian-hop extract combination with adenosine receptors. (Müller CE, Schumacher B, Brattström A, Abourashed EA, Koetter U) Life Sci 2002 Sep 06;71(16):1939-49 PMID: 12175708 08/15/2002       71 Citations
  • The inhibitory activity of natural products on plant p-hydroxyphenylpyruvate dioxygenase. (Meazza G, Scheffler BE, Tellez MR, Rimando AM, Romagni JG, Duke SO, Nanayakkara D, Khan IA, Abourashed EA, Dayan FE) Phytochemistry 2002 Jun;60(3):281-8 PMID: 12031447 05/29/2002       135 Citations
  • High-Speed Extraction and HPLC Fingerprinting of Medicinal Plants – I. Application to Passiflora Flavonoids (E.A. Abourashed J.R. Vanderplank I.A. Khan. ) Pharm. Biol. Pharm. Biol., 2002, 40, 81-91. http://dx.doi.org/10.1076/phbi.40.2.81.5844 03/01/2002    
  • GC determination of parthenolide in feverfew products. (Abourashed EA, Khan IA) Pharmazie 2001 Dec;56(12):971-2 PMID: 11802663 01/23/2002       6 Citations
  • Separation and quantification of the major daucane esters of Ferula hermonis by HPLC. (Abourashed EA, Galal AM, El-Feraly FS, Khan IA) Planta Med 2001 Oct;67(7):681-2 PMID: 11582552 10/03/2001       25 Citations
  • Inhibitory effects of maesanin and analogs on arachidonic acid metabolizing enzymes. (Abourashed EA, Muhammad I, Resch M, Bauer R, el-Feraly FS, Hufford CD) Planta Med 2001 Jun;67(4):360-1 PMID: 11458456 07/19/2001       9 Citations
  • High-performance liquid chromatography determination of hydrastine and berberine in dietary supplements containing goldenseal. (Abourashed EA, Khan IA) J Pharm Sci 2001 Jul;90(7):817-22 PMID: 11458331 07/18/2001       55 Citations
  • Determination of heavy metals and pesticides in ginseng products. (Khan IA, Allgood J, Walker LA, Abourashed EA, Schlenk D, Benson WH) J AOAC Int 2001 May-Jun;84(3):936-9 PMID: 11417656 06/22/2001       76 Citations
  • Daucane sesquiterpenes from Ferula hermonis. (Galal AM, Abourashed EA, Ross SA, ElSohly MA, Al-Said MS, El-Feraly FS) J Nat Prod 2001 Mar;64(3):399-400 PMID: 11277769 03/30/2001       45 Citations
  • Microbial transformation of kawain and methysticin. (Abourashed EA, Khan IA) Chem Pharm Bull (Tokyo) 2000 Dec;48(12):1996-8 PMID: 11145158 01/06/2001       21 Citations
  • Determination of parthenolide in selected feverfew products by liquid chromatography. (Abourashed EA, Khan IA, Abourashed EA, Khan IA) J AOAC Int 2000 Jul-Aug;83(4):789-92 PMID: 10995104 09/20/2000       15 Citations
  • 2-Hydroxy-5-(ethanolamino)-3-(10'-Z-pentadecenyl)-1,4-benzoquinone, new microbial phase II metabolite of maesanin. (Abourashed EA, el-Feraly FS, Khan IA, Hufford CD) Chem Pharm Bull (Tokyo) 2000 Jan;48(1):45-7 PMID: 10705473 03/08/2000       3 Citations
  • Carboxylic acid microbial metabolites of the natural benzoquinone, maesanin (Abourashed EA, El-Feraly FS, Hufford CD) J Nat Prod 1999 Oct;62(10):1474 PMID: 10545055 11/02/1999    
  • Two new flavone glycosides from paullinia pinnata (Abourashed EA, Toyang NJ, Choinski J Jr, Khan IA) J Nat Prod 1999 Aug;62(8):1179-81 PMID: 10479333 09/10/1999    
  • Carboxylic acid microbial metabolites of the natural benzoquinone, maesanin (Abourashed EA, El-Feraly FS, Hufford CD) J Nat Prod 1999 May;62(5):714-6 PMID: 10346952 05/29/1999    
  • Microbial models of mammalian metabolism of xenobiotics: An updated review. (Abourashed EA, Clark AM, Hufford CD) Curr Med Chem 1999 May;6(5):359-74 PMID: 10101217 04/02/1999       100 Citations
  • Microbial Transformation of Artemether (E.A. Abourashed C.D. Hufford) J. Nat. Prod. J. Nat. Prod., 1996, 59 (3), pp 251–253 03/22/1996    
  • Last update: 08/21/2020