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Publications indexed to the term Double-Blind Method

1Nirogacestat, a γ-Secretase Inhibitor for Desmoid Tumors. (Gounder M, Ratan R, Alcindor T, Schöffski P, van der Graaf WT, Wilky BA, Riedel RF, Lim A, Smith LM, Moody S, Attia S, Chawla S, D'Amato G, Federman N, Merriam P, Van Tine BA, Vincenzi B, Benson C, Bui NQ, Chugh R, Tinoco G, Charlson J, Dileo P, Hartner L, Lapeire L, Mazzeo F, Palmerini E, Reichardt P, Stacchiotti S, Bailey HH, Burgess MA, Cote GM, Davis LE, Deshpande H, Gelderblom H, Grignani G, Loggers E, Philip T, Pressey JG, Kummar S, Kasper B) N Engl J Med 2023 Mar 09;388(10):898-912    
4High-Dose IV Hydroxocobalamin (Vitamin B12) in Septic Shock: A Double-Blind, Allocation-Concealed, Placebo-Controlled Single-Center Pilot Randomized Controlled Trial (The Intravenous Hydroxocobalamin in Septic Shock Trial). (Patel JJ, Willoughby R, Peterson J, Carver T, Zelten J, Markiewicz A, Spiegelhoff K, Hipp LA, Canales B, Szabo A, Heyland DK, Stoppe C, Zielonka J, Freed JK) Chest 2023 Feb;163(2):303-312       4 Citations
1Quantifying the intensity of adverse events with ibuprofen and oxycodone: an observational cohort study. (Ali S, Gourlay K, Yukseloglu A, Rosychuk RJ, Ortiz S, Watts R, Johnson DW, Carleton B, Le May S, Drendel AL) BMJ Paediatr Open 2022 May;6(1)    
1Repeated intravenous cardiosphere-derived cell therapy in late-stage Duchenne muscular dystrophy (HOPE-2): a multicentre, randomised, double-blind, placebo-controlled, phase 2 trial. (McDonald CM, Marbán E, Hendrix S, Hogan N, Ruckdeschel Smith R, Eagle M, Finkel RS, Tian C, Janas J, Harmelink MM, Varadhachary AS, Taylor MD, Hor KN, Mayer OH, Henricson EK, Furlong P, Ascheim DD, Rogy S, Williams P, Marbán L, HOPE-2 Study Group) Lancet 2022 Mar 12;399(10329):1049-1058       16 Citations
1Molnupiravir for Oral Treatment of Covid-19 in Nonhospitalized Patients. (Jayk Bernal A, Gomes da Silva MM, Musungaie DB, Kovalchuk E, Gonzalez A, Delos Reyes V, Martín-Quirós A, Caraco Y, Williams-Diaz A, Brown ML, Du J, Pedley A, Assaid C, Strizki J, Grobler JA, Shamsuddin HH, Tipping R, Wan H, Paschke A, Butterton JR, Johnson MG, De Anda C, MOVe-OUT Study Group) N Engl J Med 2022 Feb 10;386(6):509-520       676 Citations
3Efficacy and Safety of COVID-19 Convalescent Plasma in Hospitalized Patients: A Randomized Clinical Trial. (Ortigoza MB, Yoon H, Goldfeld KS, Troxel AB, Daily JP, Wu Y, Li Y, Wu D, Cobb GF, Baptiste G, O'Keeffe M, Corpuz MO, Ostrosky-Zeichner L, Amin A, Zacharioudakis IM, Jayaweera DT, Wu Y, Philley JV, Devine MS, Desruisseaux MS, Santin AD, Anjan S, Mathew R, Patel B, Nigo M, Upadhyay R, Kupferman T, Dentino AN, Nanchal R, Merlo CA, Hager DN, Chandran K, Lai JR, Rivera J, Bikash CR, Lasso G, Hilbert TP, Paroder M, Asencio AA, Liu M, Petkova E, Bragat A, Shaker R, McPherson DD, Sacco RL, Keller MJ, Grudzen CR, Hochman JS, Pirofski LA, CONTAIN COVID-19 Consortium for the CONTAIN COVID-19 Study Group, Parameswaran L, Corcoran AT, Rohatgi A, Wronska MW, Wu X, Srinivasan R, Deng FM, Filardo TD, Pendse J, Blaser SB, Whyte O, Gallagher JM, Thomas OE, Ramos D, Sturm-Reganato CL, Fong CC, Daus IM, Payoen AG, Chiofolo JT, Friedman MT, Wu DW, Jacobson JL, Schneider JG, Sarwar UN, Wang HE, Huebinger RM, Dronavalli G, Bai Y, Grimes CZ, Eldin KW, Umana VE, Martin JG, Heath TR, Bello FO, Ransford DL, Laurent-Rolle M, Shenoi SV, Akide-Ndunge OB, Thapa B, Peterson JL, Knauf K, Patel SU, Cheney LL, Tormey CA, Hendrickson JE) JAMA Intern Med 2022 Feb 01;182(2):115-126       38 Citations
1An observational cohort study comparing ibuprofen and oxycodone in children with fractures. (Ali S, Manaloor R, Johnson DW, Rosychuk RJ, LeMay S, Carleton B, McGrath PJ, Drendel AL, Pediatric Emergency Research Canada) PLoS One 2021;16(9):e0257021       4 Citations
1Interruption of endolysosomal trafficking leads to stroke brain injury. (Yuan D, Hu K, Loke CM, Teramoto H, Liu C, Hu B) Exp Neurol 2021 Nov;345:113827       7 Citations
1Tolerability of maintenance olaparib in newly diagnosed patients with advanced ovarian cancer and a BRCA mutation in the randomized phase III SOLO1 trial. (Colombo N, Moore K, Scambia G, Oaknin A, Friedlander M, Lisyanskaya A, Floquet A, Leary A, Sonke GS, Gourley C, Banerjee S, Oza A, González-Martín A, Aghajanian C, Bradley WH, Kim JW, Mathews C, Liu J, Lowe ES, Bloomfield R, DiSilvestro P) Gynecol Oncol 2021 Oct;163(1):41-49       9 Citations
1Safe and persistent growth-promoting effects of vosoritide in children with achondroplasia: 2-year results from an open-label, phase 3 extension study. (Savarirayan R, Tofts L, Irving M, Wilcox WR, Bacino CA, Hoover-Fong J, Font RU, Harmatz P, Rutsch F, Bober MB, Polgreen LE, Ginebreda I, Mohnike K, Charrow J, Hoernschemeyer D, Ozono K, Alanay Y, Arundel P, Kotani Y, Yasui N, White KK, Saal HM, Leiva-Gea A, Luna-González F, Mochizuki H, Basel D, Porco DM, Jayaram K, Fisheleva E, Huntsman-Labed A, Day JRS) Genet Med 2021 Dec;23(12):2443-2447       19 Citations
1Five-year maintenance of clinical response and health-related quality of life improvements in patients with moderate-to-severe psoriasis treated with guselkumab: results from VOYAGE 1 and VOYAGE 2. (Reich K, Gordon KB, Strober BE, Armstrong AW, Miller M, Shen YK, You Y, Han C, Yang YW, Foley P, Griffiths CEM) Br J Dermatol 2021 Dec;185(6):1146-1159       15 Citations
1Efficacy, safety, usability, and acceptability of risankizumab 150 mg formulation administered by prefilled syringe or by an autoinjector for moderate to severe plaque psoriasis. (Blauvelt A, Gordon KB, Lee P, Bagel J, Sofen H, Lockshin B, Soliman AM, Geng Z, Zhan T, Alperovich G, Stein Gold L) J Dermatolog Treat 2022 Jun;33(4):2085-2093       2 Citations
1A 28-day clinical trial of aerosolized hyaluronan in alpha-1 antiprotease deficiency COPD using desmosine as a surrogate marker for drug efficacy. (Cantor JO, Ma S, Liu X, Campos MA, Strange C, Stocks JM, Devine MS, El Bayadi SG, Lipchik RJ, Sandhaus RA, Turino GM) Respir Med 2021 Jun;182:106402       2 Citations
1Patient-centred outcomes and effect of disease progression on health status in patients with newly diagnosed advanced ovarian cancer and a BRCA mutation receiving maintenance olaparib or placebo (SOLO1): a randomised, phase 3 trial. (Friedlander M, Moore KN, Colombo N, Scambia G, Kim BG, Oaknin A, Lisyanskaya A, Sonke GS, Gourley C, Banerjee S, Oza A, González-Martín A, Aghajanian C, Bradley WH, Liu J, Mathews C, Selle F, Lortholary A, Lowe ES, Hettle R, Flood E, Parkhomenko E, DiSilvestro P) Lancet Oncol 2021 May;22(5):632-642       27 Citations
1Bimekizumab efficacy and safety in moderate to severe plaque psoriasis (BE READY): a multicentre, double-blind, placebo-controlled, randomised withdrawal phase 3 trial. (Gordon KB, Foley P, Krueger JG, Pinter A, Reich K, Vender R, Vanvoorden V, Madden C, White K, Cioffi C, Blauvelt A) Lancet 2021 Feb 06;397(10273):475-486       72 Citations
1Bimekizumab versus ustekinumab for the treatment of moderate to severe plaque psoriasis (BE VIVID): efficacy and safety from a 52-week, multicentre, double-blind, active comparator and placebo controlled phase 3 trial. (Reich K, Papp KA, Blauvelt A, Langley RG, Armstrong A, Warren RB, Gordon KB, Merola JF, Okubo Y, Madden C, Wang M, Cioffi C, Vanvoorden V, Lebwohl M) Lancet 2021 Feb 06;397(10273):487-498       82 Citations
3Impact of Auricular Neurostimulation in Patients Undergoing Colorectal Surgery with an Enhanced Recovery Protocol: A Pilot Randomized, Controlled Trial. (Blank JJ, Liu Y, Yin Z, Spofford CM, Ridolfi TJ, Ludwig KA, Otterson MF, Peterson CY) Dis Colon Rectum 2021 Feb 01;64(2):225-233       2 Citations
1Cardiovascular Effects of Transcranial Direct Current Stimulation and Bimanual Training in Children With Cerebral Palsy. (Keller-Ross ML, Chantigian DP, Nemanich S, Gillick BT) Pediatr Phys Ther 2021 Jan 01;33(1):11-16       1 Citation
1A Pilot Randomized, Controlled, Double-Blind Trial of Bumetanide to Treat Neonatal Seizures. (Soul JS, Bergin AM, Stopp C, Hayes B, Singh A, Fortuno CR, O'Reilly D, Krishnamoorthy K, Jensen FE, Rofeberg V, Dong M, Vinks AA, Wypij D, Staley KJ, Boston Bumetanide Trial Group) Ann Neurol 2021 Feb;89(2):327-340       34 Citations
4Two weeks of remote ischemic conditioning improves brachial artery flow mediated dilation in chronic stroke survivors. (Hyngstrom AS, Nguyen JN, Wright MT, Tarima SS, Schmit BD, Gutterman DD, Durand MJ) J Appl Physiol (1985) 2020 Dec 01;129(6):1348-1354       5 Citations
1Effect of Risankizumab on Patient-Reported Outcomes in Moderate to Severe Psoriasis: The UltIMMa-1 and UltIMMa-2 Randomized Clinical Trials. (Augustin M, Lambert J, Zema C, Thompson EHZ, Yang M, Wu EQ, Garcia-Horton V, Geng Z, Valdes JM, Joshi A, Gordon KB) JAMA Dermatol 2020 Dec 01;156(12):1344-1353       14 Citations
1Maintenance of Response Through up to 4 Years of Continuous Guselkumab Treatment of Psoriasis in the VOYAGE 2 Phase 3 Study. (Reich K, Armstrong AW, Foley P, Song M, Miller M, Shen YK, You Y, Han C, Gordon KB) Am J Clin Dermatol 2020 Dec;21(6):881-890       21 Citations
1Once-daily, subcutaneous vosoritide therapy in children with achondroplasia: a randomised, double-blind, phase 3, placebo-controlled, multicentre trial. (Savarirayan R, Tofts L, Irving M, Wilcox W, Bacino CA, Hoover-Fong J, Ullot Font R, Harmatz P, Rutsch F, Bober MB, Polgreen LE, Ginebreda I, Mohnike K, Charrow J, Hoernschemeyer D, Ozono K, Alanay Y, Arundel P, Kagami S, Yasui N, White KK, Saal HM, Leiva-Gea A, Luna-González F, Mochizuki H, Basel D, Porco DM, Jayaram K, Fisheleva E, Huntsman-Labed A, Day J) Lancet 2020 Sep 05;396(10252):684-692       61 Citations
1Non-steroidal or opioid analgesia use for children with musculoskeletal injuries (the No OUCH study): statistical analysis plan. (Heath A, Yaskina M, Hopkin G, Klassen TP, McCabe C, Offringa M, Pechlivanoglou P, Rios JD, Poonai N, Ali S, KidsCAN PERC Innovative Pediatric Clinical Trials No OUCH Study Group) Trials 2020 Sep 03;21(1):759       2 Citations
1Efficacy of Maintenance Olaparib for Patients With Newly Diagnosed Advanced Ovarian Cancer With a BRCA Mutation: Subgroup Analysis Findings From the SOLO1 Trial. (DiSilvestro P, Colombo N, Scambia G, Kim BG, Oaknin A, Friedlander M, Lisyanskaya A, Floquet A, Leary A, Sonke GS, Gourley C, Banerjee S, Oza A, González-Martín A, Aghajanian CA, Bradley WH, Mathews CA, Liu J, Lowe ES, Bloomfield R, Moore KN) J Clin Oncol 2020 Oct 20;38(30):3528-3537       47 Citations
1Impaired Vagal Efficiency Predicts Auricular Neurostimulation Response in Adolescent Functional Abdominal Pain Disorders. (Kovacic K, Kolacz J, Lewis GF, Porges SW) Am J Gastroenterol 2020 Sep;115(9):1534-1538       18 Citations
1Long-term efficacy of certolizumab pegol for the treatment of plaque psoriasis: 3-year results from two randomized phase III trials (CIMPASI-1 and CIMPASI-2). (Gordon KB, Warren RB, Gottlieb AB, Blauvelt A, Thaçi D, Leonardi C, Poulin Y, Boehnlein M, Brock F, Ecoffet C, Reich K) Br J Dermatol 2021 Apr;184(4):652-662       11 Citations
1A Biomarker-enriched, Randomized Phase II Trial of Adavosertib (AZD1775) Plus Paclitaxel and Carboplatin for Women with Platinum-sensitive TP53-mutant Ovarian Cancer. (Oza AM, Estevez-Diz M, Grischke EM, Hall M, Marmé F, Provencher D, Uyar D, Weberpals JI, Wenham RM, Laing N, Tracy M, Freshwater T, Lee MA, Liu J, Qiu J, Rose S, Rubin EH, Moore K) Clin Cancer Res 2020 Sep 15;26(18):4767-4776       52 Citations
1A Phase II Randomized Clinical Trial of the Safety and Efficacy of Intravenous Umbilical Cord Blood Infusion for Treatment of Children with Autism Spectrum Disorder. (Dawson G, Sun JM, Baker J, Carpenter K, Compton S, Deaver M, Franz L, Heilbron N, Herold B, Horrigan J, Howard J, Kosinski A, Major S, Murias M, Page K, Prasad VK, Sabatos-DeVito M, Sanfilippo F, Sikich L, Simmons R, Song A, Vermeer S, Waters-Pick B, Troy J, Kurtzberg J) J Pediatr 2020 Jul;222:164-173.e5       25 Citations
1Efficacy of risankizumab in patients with moderate-to-severe plaque psoriasis by baseline demographics, disease characteristics and prior biologic therapy: an integrated analysis of the phase III UltIMMa-1 and UltIMMa-2 studies. (Strober B, Menter A, Leonardi C, Gordon K, Lambert J, Puig L, Photowala H, Longcore M, Zhan T, Foley P) J Eur Acad Dermatol Venereol 2020 Dec;34(12):2830-2838       28 Citations
1Renal Function Improvement Following ANG-3777 Treatment in Patients at High Risk for Delayed Graft Function After Kidney Transplantation. (Bromberg JS, Weir MR, Gaber AO, Yamin MA, Goldberg ID, Mayne TJ, Cal W, Cooper M) Transplantation 2021 Feb 01;105(2):443-450       9 Citations
1Association of Presalvage Radiotherapy PSA Levels After Prostatectomy With Outcomes of Long-term Antiandrogen Therapy in Men With Prostate Cancer. (Dess RT, Sun Y, Jackson WC, Jairath NK, Kishan AU, Wallington DG, Mahal BA, Stish BJ, Zumsteg ZS, Den RB, Hall WA, Gharzai LA, Jaworski EM, Reichert ZR, Morgan TM, Mehra R, Schaeffer EM, Sartor O, Nguyen PL, Lee WR, Rosenthal SA, Michalski JM, Schipper MJ, Dignam JJ, Pisansky TM, Zietman AL, Sandler HM, Efstathiou JA, Feng FY, Shipley WU, Spratt DE) JAMA Oncol 2020 May 01;6(5):735-743       44 Citations
1NRG/RTOG 1122: A phase 2, double-blinded, placebo-controlled study of bevacizumab with and without trebananib in patients with recurrent glioblastoma or gliosarcoma. (Lee EQ, Zhang P, Wen PY, Gerstner ER, Reardon DA, Aldape KD, deGroot JF, Pan E, Raizer JJ, Kim LJ, Chmura SJ, Robins HI, Connelly JM, Battiste JD, Villano JL, Wagle N, Merrell RT, Wendland MM, Mehta MP) Cancer 2020 Jun 15;126(12):2821-2828       12 Citations
1Percutaneous Cordotomy for Pain Palliation in Advanced Cancer: A Randomized Clinical Trial Study Protocol. (Viswanathan A, Vedantam A, Williams LA, Koyyalagunta D, Abdi S, Dougherty PM, Mendoza T, Bassett RL, Hou P, Bruera E) Neurosurgery 2020 Aug 01;87(2):394-402       4 Citations
1Prognostic value of the neutrophil/lymphocyte ratio in enteropancreatic neuroendocrine tumors. (Grenader T, Pavel ME, Ruszniewski PB, Ćwikła JB, Phan AT, Raderer M, Sedláčková E, Cadiot G, Wolin EM, Capdevila J, Wall L, Rindi G, Truong Thanh XM, Caplin ME, CLARINET Study Group) Anticancer Drugs 2020 Mar;31(3):216-222       4 Citations
1Teprotumumab for the Treatment of Active Thyroid Eye Disease. (Douglas RS, Kahaly GJ, Patel A, Sile S, Thompson EHZ, Perdok R, Fleming JC, Fowler BT, Marcocci C, Marinò M, Antonelli A, Dailey R, Harris GJ, Eckstein A, Schiffman J, Tang R, Nelson C, Salvi M, Wester S, Sherman JW, Vescio T, Holt RJ, Smith TJ) N Engl J Med 2020 Jan 23;382(4):341-352       264 Citations
1A head-to-head comparison of ixekizumab vs. guselkumab in patients with moderate-to-severe plaque psoriasis: 12-week efficacy, safety and speed of response from a randomized, double-blinded trial. (Blauvelt A, Papp K, Gottlieb A, Jarell A, Reich K, Maari C, Gordon KB, Ferris LK, Langley RG, Tada Y, Lima RG, Elmaraghy H, Gallo G, Renda L, Park SY, Burge R, Bagel J, IXORA-R Study Group) Br J Dermatol 2020 Jun;182(6):1348-1358       66 Citations
1Rationale and design of the STeroids to REduce Systemic inflammation after infant heart Surgery (STRESS) trial. (Hill KD, Baldwin HS, Bichel DP, Butts RJ, Chamberlain RC, Ellis AM, Graham EM, Hickerson J, Hornik CP, Jacobs JP, Jacobs ML, Jaquiss RD, Kannankeril PJ, O'Brien SM, Torok R, Turek JW, Li JS, STRESS Network Investigators) Am Heart J 2020 Feb;220:192-202       19 Citations
1Maintenance of clinical response and consistent safety profile with up to 3 years of continuous treatment with guselkumab: Results from the VOYAGE 1 and VOYAGE 2 trials. (Reich K, Griffiths CEM, Gordon KB, Papp KA, Song M, Randazzo B, Li S, Shen YK, Han C, Kimball AB, Armstrong AW, Foley P, Blauvelt A) J Am Acad Dermatol 2020 Apr;82(4):936-945       57 Citations
2Results of the FUEL Trial. (Goldberg DJ, Zak V, Goldstein BH, Schumacher KR, Rhodes J, Penny DJ, Petit CJ, Ginde S, Menon SC, Kim SH, Kim GB, Nowlen TT, DiMaria MV, Frischhertz BP, Wagner JB, McHugh KE, McCrindle BW, Shillingford AJ, Sabati AA, Yetman AT, John AS, Richmond ME, Files MD, Payne RM, Mackie AS, Davis CK, Shahanavaz S, Hill KD, Garg R, Jacobs JP, Hamstra MS, Woyciechowski S, Rathge KA, McBride MG, Frommelt PC, Russell MW, Urbina EM, Yeager JL, Pemberton VL, Stylianou MP, Pearson GD, Paridon SM, Pediatric Heart Network Investigators) Circulation 2020 Feb 25;141(8):641-651       61 Citations
3Efficacy of Auricular Neurostimulation in Adolescents With Irritable Bowel Syndrome in a Randomized, Double-Blind Trial. (Krasaelap A, Sood MR, Li BUK, Unteutsch R, Yan K, Nugent M, Simpson P, Kovacic K) Clin Gastroenterol Hepatol 2020 Aug;18(9):1987-1994.e2       23 Citations
1Selection design phase II trial of high dosages of tamoxifen and creatine in amyotrophic lateral sclerosis. (Babu S, Macklin EA, Jackson KE, Simpson E, Mahoney K, Yu H, Walker J, Simmons Z, David WS, Barkhaus PE, Simionescu L, Dimachkie MM, Pestronk A, Salameh JS, Weiss MD, Brooks BR, Schoenfeld D, Shefner J, Aggarwal S, Cudkowicz ME, Atassi N) Amyotroph Lateral Scler Frontotemporal Degener 2020 Feb;21(1-2):15-23       10 Citations
2Effect of Vitamin C Infusion on Organ Failure and Biomarkers of Inflammation and Vascular Injury in Patients With Sepsis and Severe Acute Respiratory Failure: The CITRIS-ALI Randomized Clinical Trial. (Fowler AA 3rd, Truwit JD, Hite RD, Morris PE, DeWilde C, Priday A, Fisher B, Thacker LR 2nd, Natarajan R, Brophy DF, Sculthorpe R, Nanchal R, Syed A, Sturgill J, Martin GS, Sevransky J, Kashiouris M, Hamman S, Egan KF, Hastings A, Spencer W, Tench S, Mehkri O, Bindas J, Duggal A, Graf J, Zellner S, Yanny L, McPolin C, Hollrith T, Kramer D, Ojielo C, Damm T, Cassity E, Wieliczko A, Halquist M) JAMA 2019 Oct 01;322(13):1261-1270       470 Citations
1Niraparib in Patients with Newly Diagnosed Advanced Ovarian Cancer. (González-Martín A, Pothuri B, Vergote I, DePont Christensen R, Graybill W, Mirza MR, McCormick C, Lorusso D, Hoskins P, Freyer G, Baumann K, Jardon K, Redondo A, Moore RG, Vulsteke C, O'Cearbhaill RE, Lund B, Backes F, Barretina-Ginesta P, Haggerty AF, Rubio-Pérez MJ, Shahin MS, Mangili G, Bradley WH, Bruchim I, Sun K, Malinowska IA, Li Y, Gupta D, Monk BJ, PRIMA/ENGOT-OV26/GOG-3012 Investigators) N Engl J Med 2019 Dec 19;381(25):2391-2402       951 Citations
1Ixekizumab sustains high level of efficacy and favourable safety profile over 4 years in patients with moderate psoriasis: results from UNCOVER-3 study. (Lebwohl MG, Gordon KB, Gallo G, Zhang L, Paul C) J Eur Acad Dermatol Venereol 2020 Feb;34(2):301-309       21 Citations
3Ketamine infusion for pain control in elderly patients with multiple rib fractures: Results of a randomized controlled trial. (Kugler NW, Carver TW, Juul J, Peppard WJ, Boyle K, Drescher KM, Szabo A, Rein L, Somberg LB, Paul JS) J Trauma Acute Care Surg 2019 Nov;87(5):1181-1188       13 Citations
8Safety and Efficacy of Vasopressin After Fontan Completion: A Randomized Pilot Study. (Bigelow AM, Ghanayem NS, Thompson NE, Scott JP, Cassidy LD, Woods KJ, Woods RK, Mitchell ME, Hraŝka V, Hoffman GM) Ann Thorac Surg 2019 Dec;108(6):1865-1874       7 Citations
1Guselkumab Efficacy after Withdrawal Is Associated with Suppression of Serum IL-23-Regulated IL-17 and IL-22 in Psoriasis: VOYAGE 2 Study. (Gordon KB, Armstrong AW, Foley P, Song M, Shen YK, Li S, Muñoz-Elías EJ, Branigan P, Liu X, Reich K) J Invest Dermatol 2019 Dec;139(12):2437-2446.e1       45 Citations
1Trebananib or placebo plus carboplatin and paclitaxel as first-line treatment for advanced ovarian cancer (TRINOVA-3/ENGOT-ov2/GOG-3001): a randomised, double-blind, phase 3 trial. (Vergote I, Scambia G, O'Malley DM, Van Calster B, Park SY, Del Campo JM, Meier W, Bamias A, Colombo N, Wenham RM, Covens A, Marth C, Raza Mirza M, Kroep JR, Ma H, Pickett CA, Monk BJ, TRINOVA-3/ENGOT-ov2/GOG-3001 investigators) Lancet Oncol 2019 Jun;20(6):862-876       56 Citations
1Oral probiotics reduce halitosis in patients wearing orthodontic braces: a randomized, triple-blind, placebo-controlled trial. (Benic GZ, Farella M, Morgan XC, Viswam J, Heng NC, Cannon RD, Mei L) J Breath Res 2019 May 31;13(3):036010       29 Citations
1Doxycycline for the treatment of nodding syndrome (DONS); the study protocol of a phase II randomised controlled trial. (Idro R, Anguzu R, Ogwang R, Akun P, Abbo C, Mwaka AD, Opar B, Nakamya P, Taylor M, Elliott A, Vincent A, Newton C, Marsh K) BMC Neurol 2019 Mar 06;19(1):35       9 Citations
4Ketamine infusion for pain control in adult patients with multiple rib fractures: Results of a randomized control trial. (Carver TW, Kugler NW, Juul J, Peppard WJ, Drescher KM, Somberg LB, Szabo A, Yin Z, Paul JS) J Trauma Acute Care Surg 2019 Feb;86(2):181-188       27 Citations
1Kinematic and Neuromuscular Adaptations in Incomplete Spinal Cord Injury after High- versus Low-Intensity Locomotor Training. (Ardestani MM, Henderson CE, Salehi SH, Mahtani GB, Schmit BD, Hornby TG) J Neurotrauma 2019 Jun 15;36(12):2036-2044       10 Citations
1Maintenance Olaparib in Patients with Newly Diagnosed Advanced Ovarian Cancer. (Moore K, Colombo N, Scambia G, Kim BG, Oaknin A, Friedlander M, Lisyanskaya A, Floquet A, Leary A, Sonke GS, Gourley C, Banerjee S, Oza A, González-Martín A, Aghajanian C, Bradley W, Mathews C, Liu J, Lowe ES, Bloomfield R, DiSilvestro P) N Engl J Med 2018 Dec 27;379(26):2495-2505       1416 Citations
1Impact of Steroid Therapy on Early Growth in Infants with Biliary Atresia: The Multicenter Steroids in Biliary Atresia Randomized Trial. (Alonso EM, Ye W, Hawthorne K, Venkat V, Loomes KM, Mack CL, Hertel PM, Karpen SJ, Kerkar N, Molleston JP, Murray KF, Romero R, Rosenthal P, Schwarz KB, Shneider BL, Suchy FJ, Turmelle YP, Wang KS, Sherker AH, Sokol RJ, Bezerra JA, Magee JC, ChiLDReN Network) J Pediatr 2018 Nov;202:179-185.e4       18 Citations
1Phase 2 Trial of Selective Tyrosine Kinase 2 Inhibition in Psoriasis. (Papp K, Gordon K, Thaçi D, Morita A, Gooderham M, Foley P, Girgis IG, Kundu S, Banerjee S) N Engl J Med 2018 Oct 04;379(14):1313-1321       215 Citations
1Efficacy and safety of risankizumab in moderate-to-severe plaque psoriasis (UltIMMa-1 and UltIMMa-2): results from two double-blind, randomised, placebo-controlled and ustekinumab-controlled phase 3 trials. (Gordon KB, Strober B, Lebwohl M, Augustin M, Blauvelt A, Poulin Y, Papp KA, Sofen H, Puig L, Foley P, Ohtsuki M, Flack M, Geng Z, Gu Y, Valdes JM, Thompson EHZ, Bachelez H) Lancet 2018 Aug 25;392(10148):650-661       342 Citations
1Anxiety and depression in patients with moderate-to-severe psoriasis and comparison of change from baseline after treatment with guselkumab vs. adalimumab: results from the Phase 3 VOYAGE 2 study. (Gordon KB, Armstrong AW, Han C, Foley P, Song M, Wasfi Y, You Y, Shen YK, Reich K) J Eur Acad Dermatol Venereol 2018 Nov;32(11):1940-1949       47 Citations
1Improvement in itch and other psoriasis symptoms with brodalumab in phase 3 randomized controlled trials. (Gottlieb AB, Gordon K, Hsu S, Elewski B, Eichenfield LF, Kircik L, Rastogi S, Pillai R, Israel R) J Eur Acad Dermatol Venereol 2018 Aug;32(8):1305-1313       22 Citations
1Oral Analgesics Utilization for Children With Musculoskeletal Injury (OUCH Trial): An RCT. (Le May S, Ali S, Plint AC, Mâsse B, Neto G, Auclair MC, Drendel AL, Ballard A, Khadra C, Villeneuve E, Parent S, McGrath PJ, Leclair G, Gouin S, Pediatric Emergency Research Canada (PERC)) Pediatrics 2017 Nov;140(5)       28 Citations
1Vitamin D3 Supplementation Increases Spine Bone Mineral Density in Adolescents and Young Adults With Human Immunodeficiency Virus Infection Being Treated With Tenofovir Disoproxil Fumarate: A Randomized, Placebo-Controlled Trial. (Havens PL, Stephensen CB, Van Loan MD, Schuster GU, Woodhouse LR, Flynn PM, Gordon CM, Pan CG, Rutledge B, Harris DR, Price G, Baker A, Meyer WA 3rd, Wilson CM, Hazra R, Kapogiannis BG, Mulligan K, Adolescent Medicine Trials Network for HIV/AIDS Interventions (ATN) 109 Study Team) Clin Infect Dis 2018 Jan 06;66(2):220-228       25 Citations
1Effect of Inhaled Nitric Oxide on Survival Without Bronchopulmonary Dysplasia in Preterm Infants: A Randomized Clinical Trial. (Hasan SU, Potenziano J, Konduri GG, Perez JA, Van Meurs KP, Walker MW, Yoder BA, Newborns Treated With Nitric Oxide (NEWNO) Trial Group) JAMA Pediatr 2017 Nov 01;171(11):1081-1089       41 Citations
1Efficacy of guselkumab in subpopulations of patients with moderate-to-severe plaque psoriasis: a pooled analysis of the phase III VOYAGE 1 and VOYAGE 2 studies. (Gordon KB, Blauvelt A, Foley P, Song M, Wasfi Y, Randazzo B, Shen YK, You Y, Griffiths CEM) Br J Dermatol 2018 Jan;178(1):132-139       52 Citations
2Antiarrhythmic Drugs for Nonshockable-Turned-Shockable Out-of-Hospital Cardiac Arrest: The ALPS Study (Amiodarone, Lidocaine, or Placebo). (Kudenchuk PJ, Leroux BG, Daya M, Rea T, Vaillancourt C, Morrison LJ, Callaway CW, Christenson J, Ornato JP, Dunford JV, Wittwer L, Weisfeldt ML, Aufderheide TP, Vilke GM, Idris AH, Stiell IG, Colella MR, Kayea T, Egan D, Desvigne-Nickens P, Gray P, Gray R, Straight R, Dorian P, Resuscitation Outcomes Consortium Investigators) Circulation 2017 Nov 28;136(22):2119-2131       20 Citations
1A comparison of the recovery profiles of desflurane and isoflurane anesthesia in patients undergoing elective supratentorial craniotomy: A randomized controlled trial. (Paul AP, Vedantam A, Korula G, Chacko AG) Neurol India 2017;65(5):1053-1058       2 Citations
4Neurostimulation for abdominal pain-related functional gastrointestinal disorders in adolescents: a randomised, double-blind, sham-controlled trial. (Kovacic K, Hainsworth K, Sood M, Chelimsky G, Unteutsch R, Nugent M, Simpson P, Miranda A) Lancet Gastroenterol Hepatol 2017 Oct;2(10):727-737       71 Citations
2Updated analysis of CALGB (Alliance) 100104 assessing lenalidomide versus placebo maintenance after single autologous stem-cell transplantation for multiple myeloma: a randomised, double-blind, phase 3 trial. (Holstein SA, Jung SH, Richardson PG, Hofmeister CC, Hurd DD, Hassoun H, Giralt S, Stadtmauer EA, Weisdorf DJ, Vij R, Moreb JS, Callander NS, van Besien K, Gentile TG, Isola L, Maziarz RT, Bashey A, Landau H, Martin T, Qazilbash MH, Rodriguez C, McClune B, Schlossman RL, Smith SE, Hars V, Owzar K, Jiang C, Boyd M, Schultz C, Wilson M, Hari P, Pasquini MC, Horowitz MM, Shea TC, Devine SM, Linker C, Anderson KC, McCarthy PL) Lancet Haematol 2017 Sep;4(9):e431-e442       114 Citations
1Intraoperative ketamine for prevention of postoperative delirium or pain after major surgery in older adults: an international, multicentre, double-blind, randomised clinical trial. (Avidan MS, Maybrier HR, Abdallah AB, Jacobsohn E, Vlisides PE, Pryor KO, Veselis RA, Grocott HP, Emmert DA, Rogers EM, Downey RJ, Yulico H, Noh GJ, Lee YH, Waszynski CM, Arya VK, Pagel PS, Hudetz JA, Muench MR, Fritz BA, Waberski W, Inouye SK, Mashour GA, PODCAST Research Group) Lancet 2017 Jul 15;390(10091):267-275       249 Citations
1Safety and tolerability of long-acting cabotegravir injections in HIV-uninfected men (ECLAIR): a multicentre, double-blind, randomised, placebo-controlled, phase 2a trial. (Markowitz M, Frank I, Grant RM, Mayer KH, Elion R, Goldstein D, Fisher C, Sobieszczyk ME, Gallant JE, Van Tieu H, Weinberg W, Margolis DA, Hudson KJ, Stancil BS, Ford SL, Patel P, Gould E, Rinehart AR, Smith KY, Spreen WR) Lancet HIV 2017 Aug;4(8):e331-e340       152 Citations
1Teprotumumab for Thyroid-Associated Ophthalmopathy. (Smith TJ, Kahaly GJ, Ezra DG, Fleming JC, Dailey RA, Tang RA, Harris GJ, Antonelli A, Salvi M, Goldberg RA, Gigantelli JW, Couch SM, Shriver EM, Hayek BR, Hink EM, Woodward RM, Gabriel K, Magni G, Douglas RS) N Engl J Med 2017 May 04;376(18):1748-1761       382 Citations
1A phase 2, randomized, double-blind, placebo- controlled study of chemo-immunotherapy combination using motolimod with pegylated liposomal doxorubicin in recurrent or persistent ovarian cancer: a Gynecologic Oncology Group partners study. (Monk BJ, Brady MF, Aghajanian C, Lankes HA, Rizack T, Leach J, Fowler JM, Higgins R, Hanjani P, Morgan M, Edwards R, Bradley W, Kolevska T, Foukas P, Swisher EM, Anderson KS, Gottardo R, Bryan JK, Newkirk M, Manjarrez KL, Mannel RS, Hershberg RM, Coukos G) Ann Oncol 2017 May 01;28(5):996-1004       52 Citations
1Endocannabinoid and Opioid System Interactions in Exercise-Induced Hypoalgesia. (Crombie KM, Brellenthin AG, Hillard CJ, Koltyn KF) Pain Med 2018 Jan 01;19(1):118-123       54 Citations
1A stratified randomized double-blind phase II trial of celecoxib for treating patients with cervical intraepithelial neoplasia: The potential predictive value of VEGF serum levels: An NRG Oncology/Gynecologic Oncology Group study. (Rader JS, Sill MW, Beumer JH, Lankes HA, Benbrook DM, Garcia F, Trimble C, Tate Thigpen J, Lieberman R, Zuna RE, Leath CA 3rd, Spirtos NM, Byron J, Thaker PH, Lele S, Alberts D) Gynecol Oncol 2017 May;145(2):291-297       14 Citations
4Moderate, Short-Term, Local Hyperglycemia Attenuates Forearm Endothelium-Dependent Vasodilation After Transient Ischemia-Reperfusion in Human Volunteers. (Ebert TJ, Novalija J, Barney JA, Uhrich TD, Arain SR, Freed JK, Pagel PS) J Cardiothorac Vasc Anesth 2017 Oct;31(5):1649-1655       2 Citations
1Continuous dosing versus interrupted therapy with ixekizumab: an integrated analysis of two phase 3 trials in psoriasis. (Blauvelt A, Papp KA, Sofen H, Augustin M, Yosipovitch G, Katoh N, Mrowietz U, Ohtsuki M, Poulin Y, Shrom D, Burge R, See K, Mallbris L, Gordon KB) J Eur Acad Dermatol Venereol 2017 Jun;31(6):1004-1013       46 Citations
1Impact of DPP-4 inhibition on acute and chronic endothelial function in humans with type 2 diabetes on background metformin therapy. (Widlansky ME, Puppala VK, Suboc TM, Malik M, Branum A, Signorelli K, Wang J, Ying R, Tanner MJ, Tyagi S) Vasc Med 2017 Jun;22(3):189-196       27 Citations
1Radiation with or without Antiandrogen Therapy in Recurrent Prostate Cancer. (Shipley WU, Seiferheld W, Lukka HR, Major PP, Heney NM, Grignon DJ, Sartor O, Patel MP, Bahary JP, Zietman AL, Pisansky TM, Zeitzer KL, Lawton CA, Feng FY, Lovett RD, Balogh AG, Souhami L, Rosenthal SA, Kerlin KJ, Dignam JJ, Pugh SL, Sandler HM, NRG Oncology RTOG) N Engl J Med 2017 Feb 02;376(5):417-428       416 Citations
1Efficacy and safety of guselkumab, an anti-interleukin-23 monoclonal antibody, compared with adalimumab for the treatment of patients with moderate to severe psoriasis with randomized withdrawal and retreatment: Results from the phase III, double-blind, placebo- and active comparator-controlled VOYAGE 2 trial. (Reich K, Armstrong AW, Foley P, Song M, Wasfi Y, Randazzo B, Li S, Shen YK, Gordon KB) J Am Acad Dermatol 2017 Mar;76(3):418-431       456 Citations
1CD25 Blockade Delays Regulatory T Cell Reconstitution and Does Not Prevent Graft-versus-Host Disease After Allogeneic Hematopoietic Cell Transplantation. (Locke FL, Pidala J, Storer B, Martin PJ, Pulsipher MA, Chauncey TR, Jacobsen N, Kröger N, Walker I, Light S, Shaw BE, Beato F, Laport GG, Nademanee A, Keating A, Socie G, Anasetti C) Biol Blood Marrow Transplant 2017 Mar;23(3):405-411       12 Citations
1A proof-of-concept trial of protein kinase C iota inhibition with auranofin for the paclitaxel-induced acute pain syndrome. (Jatoi A, Grudem ME, Dockter TJ, Block MS, Villasboas JC, Tan A, Deering E, Kasi PM, Mansfield AS, Botero JP, Okuno SH, Smith DR, Fields AP) Support Care Cancer 2017 Mar;25(3):833-838       7 Citations
1Late-night salivary cortisol may be valuable for assessing treatment response in patients with Cushing's disease: 12-month, Phase III pasireotide study. (Findling JW, Fleseriu M, Newell-Price J, Petersenn S, Pivonello R, Kandra A, Pedroncelli AM, Biller BM) Endocrine 2016 Nov;54(2):516-523       19 Citations
4Short-Term Angiotensin Subtype 1 Receptor Blockade Does Not Alter the Circulatory Responses to Sympathetic Nervous System Modulation in Healthy Volunteers Before and During Sevoflurane Anesthesia: Results of a Pilot Study. (Arain SR, Freed JK, Novalija J, Pagel PS, Ebert TJ) J Cardiothorac Vasc Anesth 2016 Dec;30(6):1479-1484       1 Citation
1Anti-TGF-β1 Antibody Therapy in Patients with Diabetic Nephropathy. (Voelker J, Berg PH, Sheetz M, Duffin K, Shen T, Moser B, Greene T, Blumenthal SS, Rychlik I, Yagil Y, Zaoui P, Lewis JB) J Am Soc Nephrol 2017 Mar;28(3):953-962       167 Citations
1Early clinical response to tofacitinib treatment as a predictor of subsequent efficacy: Results from two phase 3 studies of patients with moderate-to-severe plaque psoriasis. (Tan H, Valdez H, Griffins CE, Mrowietz U, Tallman A, Wolk R, Gordon K) J Dermatolog Treat 2017 Feb;28(1):3-7       8 Citations
1Montelukast for Children with Obstructive Sleep Apnea: Results of a Double-Blind, Randomized, Placebo-Controlled Trial. (Kheirandish-Gozal L, Bandla HP, Gozal D) Ann Am Thorac Soc 2016 Oct;13(10):1736-1741       85 Citations
1Clinical and demographic correlates of medication and visit adherence in a large randomized controlled trial. (Whittle J, Yamal JM, Williamson JD, Ford CE, Probstfield JL, Beard BL, Marginean H, Hamilton BP, Suhan PS, Davis BR, ALLHAT Collaborative Research Group) BMC Health Serv Res 2016 Jul 08;16:236       9 Citations
1Effect of Deutetrabenazine on Chorea Among Patients With Huntington Disease: A Randomized Clinical Trial. (Huntington Study Group, Frank S, Testa CM, Stamler D, Kayson E, Davis C, Edmondson MC, Kinel S, Leavitt B, Oakes D, O'Neill C, Vaughan C, Goldstein J, Herzog M, Snively V, Whaley J, Wong C, Suter G, Jankovic J, Jimenez-Shahed J, Hunter C, Claassen DO, Roman OC, Sung V, Smith J, Janicki S, Clouse R, Saint-Hilaire M, Hohler A, Turpin D, James RC, Rodriguez R, Rizer K, Anderson KE, Heller H, Carlson A, Criswell S, Racette BA, Revilla FJ, Nucifora F Jr, Margolis RL, Ong M, Mendis T, Mendis N, Singer C, Quesada M, Paulsen JS, Brashers-Krug T, Miller A, Kerr J, Dubinsky RM, Gray C, Factor SA, Sperin E, Molho E, Eglow M, Evans S, Kumar R, Reeves C, Samii A, Chouinard S, Beland M, Scott BL, Hickey PT, Esmail S, Fung WL, Gibbons C, Qi L, Colcher A, Hackmyer C, McGarry A, Klos K, Gudesblatt M, Fafard L, Graffitti L, Schneider DP, Dhall R, Wojcieszek JM, LaFaver K, Duker A, Neefus E, Wilson-Perez H, Shprecher D, Wall P, Blindauer KA, Wheeler L, Boyd JT, Houston E, Farbman ES, Agarwal P, Eberly SW, Watts A, Tariot PN, Feigin A, Evans S, Beck C, Orme C, Edicola J, Christopher E) JAMA 2016 Jul 05;316(1):40-50       133 Citations
1The Association Between Antihypertensive Medication Nonadherence and Visit-to-Visit Variability of Blood Pressure: Findings From the Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial. (Kronish IM, Lynch AI, Oparil S, Whittle J, Davis BR, Simpson LM, Krousel-Wood M, Cushman WC, Chang TI, Muntner P) Hypertension 2016 Jul;68(1):39-45       65 Citations
4Amiodarone, Lidocaine, or Placebo in Out-of-Hospital Cardiac Arrest. (Kudenchuk PJ, Brown SP, Daya M, Rea T, Nichol G, Morrison LJ, Leroux B, Vaillancourt C, Wittwer L, Callaway CW, Christenson J, Egan D, Ornato JP, Weisfeldt ML, Stiell IG, Idris AH, Aufderheide TP, Dunford JV, Colella MR, Vilke GM, Brienza AM, Desvigne-Nickens P, Gray PC, Gray R, Seals N, Straight R, Dorian P, Resuscitation Outcomes Consortium Investigators) N Engl J Med 2016 May 05;374(18):1711-22       281 Citations
1Cardio-protection afforded by β-blockade is maintained during resistance exercise. (Conviser JM, Ng AV, Rockey SS, Thomas DP) J Sci Med Sport 2017 Feb;20(2):196-201       3 Citations
1Effect of Ixekizumab Treatment on Work Productivity for Patients With Moderate-to-Severe Plaque Psoriasis: Analysis of Results From 3 Randomized Phase 3 Clinical Trials. (Armstrong AW, Lynde CW, McBride SR, Ståhle M, Edson-Heredia E, Zhu B, Amato D, Nikaï E, Yang FE, Gordon KB) JAMA Dermatol 2016 Jun 01;152(6):661-9       43 Citations
1A randomized, blinded, placebo-controlled trial of education and iron supplementation for mitigation of iron deficiency in regular blood donors. (Mast AE, Bialkowski W, Bryant BJ, Wright DJ, Birch R, Kiss JE, D'Andrea P, Cable RG, Spencer BR) Transfusion 2016 Jun;56(6 Pt 2):1588-97       47 Citations
1Heterogeneity of Treatment Response to Citalopram for Patients With Alzheimer's Disease With Aggression or Agitation: The CitAD Randomized Clinical Trial. (Schneider LS, Frangakis C, Drye LT, Devanand DP, Marano CM, Mintzer J, Mulsant BH, Munro CA, Newell JA, Pawluczyk S, Pelton G, Pollock BG, Porsteinsson AP, Rabins PV, Rein L, Rosenberg PB, Shade D, Weintraub D, Yesavage J, Lyketsos CG, CitAD Research Group) Am J Psychiatry 2016 May 01;173(5):465-72       38 Citations
7A Pilot Study of Antithrombin Replacement Prior to Cardiopulmonary Bypass in Neonates. (Niebler RA, Woods KJ, Murkowski K, Ghanayem NS, Hoffman G, Mitchell ME, Punzalan RC, Scott JP, Simpson P, Tweddell JS) Artif Organs 2016 Jan;40(1):80-5       7 Citations
1Efficacy of ruxolitinib on hepatomegaly in patients with myelofibrosis. (Verstovsek S, Atallah E, Mascarenhas J, Sun H, Montgomery M, Gupta V, Mesa R, Gotlib J) Leukemia 2016 Jun;30(6):1413-5       6 Citations
1Efficacy of electrical stimulation and exercise for dysphagia in patients with head and neck cancer: A randomized clinical trial. (Langmore SE, McCulloch TM, Krisciunas GP, Lazarus CL, Van Daele DJ, Pauloski BR, Rybin D, Doros G) Head Neck 2016 Apr;38 Suppl 1(Suppl 1):E1221-31       66 Citations
1Phase 3 Studies Comparing Brodalumab with Ustekinumab in Psoriasis. (Lebwohl M, Strober B, Menter A, Gordon K, Weglowska J, Puig L, Papp K, Spelman L, Toth D, Kerdel F, Armstrong AW, Stingl G, Kimball AB, Bachelez H, Wu JJ, Crowley J, Langley RG, Blicharski T, Paul C, Lacour JP, Tyring S, Kircik L, Chimenti S, Callis Duffin K, Bagel J, Koo J, Aras G, Li J, Song W, Milmont CE, Shi Y, Erondu N, Klekotka P, Kotzin B, Nirula A) N Engl J Med 2015 Oct;373(14):1318-28       585 Citations
1Can Creatine Supplementation Improve Body Composition and Objective Physical Function in Rheumatoid Arthritis Patients? A Randomized Controlled Trial. (Wilkinson TJ, Lemmey AB, Jones JG, Sheikh F, Ahmad YA, Chitale S, Maddison PJ, O'brien TD) Arthritis Care Res (Hoboken) 2016 Jun;68(6):729-37       30 Citations
1Increased Lower Limb Spasticity but Not Strength or Function Following a Single-Dose Serotonin Reuptake Inhibitor in Chronic Stroke. (Gourab K, Schmit BD, Hornby TG) Arch Phys Med Rehabil 2015 Dec;96(12):2112-9       14 Citations
1Surgical Pain Control With Ropivacaine by Atomized Delivery (Spray): A Randomized Controlled Trial. (Collins GG, Gadzinski JA, Fitzgerald GD, Sheran J, Wagner S, Edelstein S, Mueller ER) J Minim Invasive Gynecol 2016 Jan;23(1):40-5       10 Citations
1A Phase 2 Trial of Guselkumab versus Adalimumab for Plaque Psoriasis. (Gordon KB, Duffin KC, Bissonnette R, Prinz JC, Wasfi Y, Li S, Shen YK, Szapary P, Randazzo B, Reich K) N Engl J Med 2015 Jul 09;373(2):136-44       247 Citations
1Apremilast, an oral phosphodiesterase 4 (PDE4) inhibitor, in patients with moderate to severe plaque psoriasis: Results of a phase III, randomized, controlled trial (Efficacy and Safety Trial Evaluating the Effects of Apremilast in Psoriasis [ESTEEM] 1). (Papp K, Reich K, Leonardi CL, Kircik L, Chimenti S, Langley RG, Hu C, Stevens RM, Day RM, Gordon KB, Korman NJ, Griffiths CE) J Am Acad Dermatol 2015 Jul;73(1):37-49       412 Citations
1Changes in ventricular remodelling and clinical status during the year following a single administration of stromal cell-derived factor-1 non-viral gene therapy in chronic ischaemic heart failure patients: the STOP-HF randomized Phase II trial. (Chung ES, Miller L, Patel AN, Anderson RD, Mendelsohn FO, Traverse J, Silver KH, Shin J, Ewald G, Farr MJ, Anwaruddin S, Plat F, Fisher SJ, AuWerter AT, Pastore JM, Aras R, Penn MS) Eur Heart J 2015 Sep 01;36(33):2228-38       125 Citations
1Long-term use of ticagrelor in patients with prior myocardial infarction. (Bonaca MP, Bhatt DL, Cohen M, Steg PG, Storey RF, Jensen EC, Magnani G, Bansilal S, Fish MP, Im K, Bengtsson O, Oude Ophuis T, Budaj A, Theroux P, Ruda M, Hamm C, Goto S, Spinar J, Nicolau JC, Kiss RG, Murphy SA, Wiviott SD, Held P, Braunwald E, Sabatine MS, PEGASUS-TIMI 54 Steering Committee and Investigators) N Engl J Med 2015 May 07;372(19):1791-800       1462 Citations
1Valganciclovir for symptomatic congenital cytomegalovirus disease. (Kimberlin DW, Jester PM, Sánchez PJ, Ahmed A, Arav-Boger R, Michaels MG, Ashouri N, Englund JA, Estrada B, Jacobs RF, Romero JR, Sood SK, Whitworth MS, Abzug MJ, Caserta MT, Fowler S, Lujan-Zilbermann J, Storch GA, DeBiasi RL, Han JY, Palmer A, Weiner LB, Bocchini JA, Dennehy PH, Finn A, Griffiths PD, Luck S, Gutierrez K, Halasa N, Homans J, Shane AL, Sharland M, Simonsen K, Vanchiere JA, Woods CR, Sabo DL, Aban I, Kuo H, James SH, Prichard MN, Griffin J, Giles D, Acosta EP, Whitley RJ, National Institute of Allergy and Infectious Diseases Collaborative Antiviral Study Group) N Engl J Med 2015 Mar 05;372(10):933-43       466 Citations
1Aflibercept, bevacizumab, or ranibizumab for diabetic macular edema. (Diabetic Retinopathy Clinical Research Network, Wells JA, Glassman AR, Ayala AR, Jampol LM, Aiello LP, Antoszyk AN, Arnold-Bush B, Baker CW, Bressler NM, Browning DJ, Elman MJ, Ferris FL, Friedman SM, Melia M, Pieramici DJ, Sun JK, Beck RW) N Engl J Med 2015 Mar 26;372(13):1193-203       1125 Citations
1Randomized, double-blind, dose-escalation trial of triptorelin for ovary protection in childhood-onset systemic lupus erythematosus. (Brunner HI, Silva CA, Reiff A, Higgins GC, Imundo L, Williams CB, Wallace CA, Aikawa NE, Nelson S, Klein-Gitelman MS, Rose SR) Arthritis Rheumatol 2015 May;67(5):1377-85       29 Citations
1Very early administration of progesterone for acute traumatic brain injury. (Wright DW, Yeatts SD, Silbergleit R, Palesch YY, Hertzberg VS, Frankel M, Goldstein FC, Caveney AF, Howlett-Smith H, Bengelink EM, Manley GT, Merck LH, Janis LS, Barsan WG, NETT Investigators) N Engl J Med 2014 Dec 25;371(26):2457-66       400 Citations
1The strategies to reduce iron deficiency in blood donors randomized trial: design, enrolment and early retention. (Bialkowski W, Bryant BJ, Schlumpf KS, Wright DJ, Birch R, Kiss JE, D'Andrea P, Cable RG, Spencer BR, Vij V, Mast AE) Vox Sang 2015 Feb;108(2):178-85       22 Citations
1It's the thought that counts: examining the task-dependent effects of transcranial direct current stimulation on executive function. (Gill J, Shah-Basak PP, Hamilton R) Brain Stimul 2015;8(2):253-9       153 Citations
1Weekly versus monthly testosterone administration on fast and slow skeletal muscle fibers in older adult males. (Fitts RH, Peters JR, Dillon EL, Durham WJ, Sheffield-Moore M, Urban RJ) J Clin Endocrinol Metab 2015 Feb;100(2):E223-31       21 Citations
1Bupropion, smoking cessation, and health-related quality of life following an acute myocardial infarction. (Zhang DD, Eisenberg MJ, Grandi SM, Joseph L, O'Loughlin J, Paradis G, Lozano P, Filion KB) J Popul Ther Clin Pharmacol 2014;21(3):e346-56       6 Citations
2The IBV Valve trial: a multicenter, randomized, double-blind trial of endobronchial therapy for severe emphysema. (Wood DE, Nader DA, Springmeyer SC, Elstad MR, Coxson HO, Chan A, Rai NS, Mularski RA, Cooper CB, Wise RA, Jones PW, Mehta AC, Gonzalez X, Sterman DH, IBV Valve Trial Research Team) J Bronchology Interv Pulmonol 2014 Oct;21(4):288-97       45 Citations
1Bilateral administration of autologous CD133+ cells in ambulatory patients with refractory critical limb ischemia: lessons learned from a pilot randomized, double-blind, placebo-controlled trial. (Raval AN, Schmuck EG, Tefera G, Leitzke C, Ark CV, Hei D, Centanni JM, de Silva R, Koch J, Chappell RG, Hematti P) Cytotherapy 2014 Dec;16(12):1720-32       36 Citations
1The Prevention of Delirium and Complications Associated with Surgical Treatments (PODCAST) study: protocol for an international multicentre randomised controlled trial. (Avidan MS, Fritz BA, Maybrier HR, Muench MR, Escallier KE, Chen Y, Ben Abdallah A, Veselis RA, Hudetz JA, Pagel PS, Noh G, Pryor K, Kaiser H, Arya VK, Pong R, Jacobsohn E, Grocott HP, Choi S, Downey RJ, Inouye SK, Mashour GA) BMJ Open 2014 Sep 17;4(9):e005651       36 Citations
1Lanreotide in metastatic enteropancreatic neuroendocrine tumors. (Caplin ME, Pavel M, Ćwikła JB, Phan AT, Raderer M, Sedláčková E, Cadiot G, Wolin EM, Capdevila J, Wall L, Rindi G, Langley A, Martinez S, Blumberg J, Ruszniewski P, CLARINET Investigators) N Engl J Med 2014 Jul 17;371(3):224-33       823 Citations
1Effect of pegaptanib sodium 0.3 mg intravitreal injections (Macugen) in intraocular pressure: posthoc analysis from V.I.S.I.O.N. study. (Boyer DS, Goldbaum M, Leys AM, Starita C, V.I.S.I.O.N. Study Group) Br J Ophthalmol 2014 Nov;98(11):1543-6       15 Citations
1Randomized, double-blind, placebo-controlled trial of the efficacy and safety of rilonacept in the treatment of systemic juvenile idiopathic arthritis. (Ilowite NT, Prather K, Lokhnygina Y, Schanberg LE, Elder M, Milojevic D, Verbsky JW, Spalding SJ, Kimura Y, Imundo LF, Punaro MG, Sherry DD, Tarvin SE, Zemel LS, Birmingham JD, Gottlieb BS, Miller ML, O'Neil K, Ruth NM, Wallace CA, Singer NG, Sandborg CI) Arthritis Rheumatol 2014 Sep;66(9):2570-9       118 Citations
1One-year outcomes of out-of-hospital administration of intravenous glucose, insulin, and potassium (GIK) in patients with suspected acute coronary syndromes (from the IMMEDIATE [Immediate Myocardial Metabolic Enhancement During Initial Assessment and Treatment in Emergency Care] Trial). (Selker HP, Udelson JE, Massaro JM, Ruthazer R, D'Agostino RB, Griffith JL, Sheehan PR, Desvigne-Nickens P, Rosenberg Y, Tian X, Vickery EM, Atkins JM, Aufderheide TP, Sayah AJ, Pirrallo RG, Levy MK, Richards ME, Braude DA, Doyle DD, Frascone RJ, Kosiak DJ, Leaming JM, Van Gelder CM, Walter GP, Wayne MA, Woolard RH, Beshansky JR) Am J Cardiol 2014 May 15;113(10):1599-605       35 Citations
3Resuscitation Outcomes Consortium-Amiodarone, Lidocaine or Placebo Study (ROC-ALPS): Rationale and methodology behind an out-of-hospital cardiac arrest antiarrhythmic drug trial. (Kudenchuk PJ, Brown SP, Daya M, Morrison LJ, Grunau BE, Rea T, Aufderheide T, Powell J, Leroux B, Vaillancourt C, Larsen J, Wittwer L, Colella MR, Stephens SW, Gamber M, Egan D, Dorian P, Resuscitation Outcomes Consortium Investigators) Am Heart J 2014 May;167(5):653-9.e4       51 Citations
1Transferring from clopidogrel loading dose to prasugrel loading dose in acute coronary syndrome patients. High on-treatment platelet reactivity analysis of the TRIPLET trial. (Diodati JG, Saucedo JF, Cardillo TE, Jakubowski JA, Henneges C, Effron MB, Lipkin FR, Walker JR, Duvvuru S, Sundseth SS, Fisher HN, Angiolillo DJ) Thromb Haemost 2014 Aug;112(2):311-22       8 Citations
1A randomized clinical trial of high-dosage coenzyme Q10 in early Parkinson disease: no evidence of benefit. (Parkinson Study Group QE3 Investigators, Beal MF, Oakes D, Shoulson I, Henchcliffe C, Galpern WR, Haas R, Juncos JL, Nutt JG, Voss TS, Ravina B, Shults CM, Helles K, Snively V, Lew MF, Griebner B, Watts A, Gao S, Pourcher E, Bond L, Kompoliti K, Agarwal P, Sia C, Jog M, Cole L, Sultana M, Kurlan R, Richard I, Deeley C, Waters CH, Figueroa A, Arkun A, Brodsky M, Ondo WG, Hunter CB, Jimenez-Shahed J, Palao A, Miyasaki JM, So J, Tetrud J, Reys L, Smith K, Singer C, Blenke A, Russell DS, Cotto C, Friedman JH, Lannon M, Zhang L, Drasby E, Kumar R, Subramanian T, Ford DS, Grimes DA, Cote D, Conway J, Siderowf AD, Evatt ML, Sommerfeld B, Lieberman AN, Okun MS, Rodriguez RL, Merritt S, Swartz CL, Martin WR, King P, Stover N, Guthrie S, Watts RL, Ahmed A, Fernandez HH, Winters A, Mari Z, Dawson TM, Dunlop B, Feigin AS, Shannon B, Nirenberg MJ, Ogg M, Ellias SA, Thomas CA, Frei K, Bodis-Wollner I, Glazman S, Mayer T, Hauser RA, Pahwa R, Langhammer A, Ranawaya R, Derwent L, Sethi KD, Farrow B, Prakash R, Litvan I, Robinson A, Sahay A, Gartner M, Hinson VK, Markind S, Pelikan M, Perlmutter JS, Hartlein J, Molho E, Evans S, Adler CH, Duffy A, Lind M, Elmer L, Davis K, Spears J, Wilson S, Leehey MA, Hermanowicz N, Niswonger S, Shill HA, Obradov S, Rajput A, Cowper M, Lessig S, Song D, Fontaine D, Zadikoff C, Williams K, Blindauer KA, Bergholte J, Propsom CS, Stacy MA, Field J, Mihaila D, Chilton M, Uc EY, Sieren J, Simon DK, Kraics L, Silver A, Boyd JT, Hamill RW, Ingvoldstad C, Young J, Thomas K, Kostyk SK, Wojcieszek J, Pfeiffer RF, Panisset M, Beland M, Reich SG, Cines M, Zappala N, Rivest J, Zweig R, Lumina LP, Hilliard CL, Grill S, Kellermann M, Tuite P, Rolandelli S, Kang UJ, Young J, Rao J, Cook MM, Severt L, Boyar K) JAMA Neurol 2014 May;71(5):543-52       267 Citations
2Randomized, double-blind, placebo-controlled trial of soluble tumor necrosis factor receptor: enbrel (etanercept) for the treatment of idiopathic pneumonia syndrome after allogeneic stem cell transplantation: blood and marrow transplant clinical trials network protocol. (Yanik GA, Horowitz MM, Weisdorf DJ, Logan BR, Ho VT, Soiffer RJ, Carter SL, Wu J, Wingard JR, Difronzo NL, Ferrara JL, Giralt S, Madtes DK, Drexler R, White ES, Cooke KR) Biol Blood Marrow Transplant 2014 Jun;20(6):858-64       51 Citations
1Pasireotide treatment significantly improves clinical signs and symptoms in patients with Cushing's disease: results from a Phase III study. (Pivonello R, Petersenn S, Newell-Price J, Findling JW, Gu F, Maldonado M, Trovato A, Hughes G, Salgado LR, Lacroix A, Schopohl J, Biller BM, Pasireotide B2305 Study Group) Clin Endocrinol (Oxf) 2014 Sep;81(3):408-17       87 Citations
1Secondary analyses of the effects of lutein/zeaxanthin on age-related macular degeneration progression: AREDS2 report No. 3. (Age-Related Eye Disease Study 2 (AREDS2) Research Group, Chew EY, Clemons TE, Sangiovanni JP, Danis RP, Ferris FL 3rd, Elman MJ, Antoszyk AN, Ruby AJ, Orth D, Bressler SB, Fish GE, Hubbard GB, Klein ML, Chandra SR, Blodi BA, Domalpally A, Friberg T, Wong WT, Rosenfeld PJ, Agrón E, Toth CA, Bernstein PS, Sperduto RD) JAMA Ophthalmol 2014 Feb;132(2):142-9       297 Citations
1Effect of antispastic drugs on motor reflexes and voluntary muscle contraction in incomplete spinal cord injury. (Chu VW, Hornby TG, Schmit BD) Arch Phys Med Rehabil 2014 Apr;95(4):622-32       12 Citations
1Double-blind, randomized, phase 2 trial of maintenance sunitinib versus placebo after response to chemotherapy in patients with advanced urothelial carcinoma. (Grivas PD, Daignault S, Tagawa ST, Nanus DM, Stadler WM, Dreicer R, Kohli M, Petrylak DP, Vaughn DJ, Bylow KA, Wong SG, Sottnik JL, Keller ET, Al-Hawary M, Smith DC, Hussain M) Cancer 2014 Mar 01;120(5):692-701       90 Citations
1Impact of brodalumab treatment on psoriasis symptoms and health-related quality of life: use of a novel patient-reported outcome measure, the Psoriasis Symptom Inventory. (Gordon KB, Kimball AB, Chau D, Viswanathan HN, Li J, Revicki DA, Kricorian G, Ortmeier BG) Br J Dermatol 2014 Mar;170(3):705-15       37 Citations
1Association of higher plasma vitamin D binding protein and lower free calcitriol levels with tenofovir disoproxil fumarate use and plasma and intracellular tenofovir pharmacokinetics: cause of a functional vitamin D deficiency? (Havens PL, Kiser JJ, Stephensen CB, Hazra R, Flynn PM, Wilson CM, Rutledge B, Bethel J, Pan CG, Woodhouse LR, Van Loan MD, Liu N, Lujan-Zilbermann J, Baker A, Kapogiannis BG, Gordon CM, Mulligan K, Adolescent Medicine Trials Network for HIV/AIDS Interventions (ATN) 063 Study Team) Antimicrob Agents Chemother 2013 Nov;57(11):5619-28       48 Citations
1Probiotic administration in early life, atopy, and asthma: a meta-analysis of clinical trials. (Elazab N, Mendy A, Gasana J, Vieira ER, Quizon A, Forno E) Pediatrics 2013 Sep;132(3):e666-76       207 Citations
1Comparative cost-effectiveness analysis of voriconazole and fluconazole for prevention of invasive fungal infection in patients receiving allogeneic hematopoietic cell transplants. (Mauskopf J, Chirila C, Graham J, Gersten ID, Leather H, Maziarz RT, Baden LR, Bolaños-Meade J, Brown JM, Walsh TJ, Horowitz MH, Kurtzberg J, Marr KA, Wingard JR) Am J Health Syst Pharm 2013 Sep 01;70(17):1518-27       13 Citations
1Reduction of cancer-related fatigue with dexamethasone: a double-blind, randomized, placebo-controlled trial in patients with advanced cancer. (Yennurajalingam S, Frisbee-Hume S, Palmer JL, Delgado-Guay MO, Bull J, Phan AT, Tannir NM, Litton JK, Reddy A, Hui D, Dalal S, Massie L, Reddy SK, Bruera E) J Clin Oncol 2013 Sep 01;31(25):3076-82       228 Citations
1Digital animation versus textbook in teaching plastic surgery techniques to novice learners. (Flores RL, DeMoss P, Klene C, Havlik RJ, Tholpady S) Plast Reconstr Surg 2013 Jul;132(1):101e-109e       14 Citations
1High variability in baseline urinary free cortisol values in patients with Cushing's disease. (Petersenn S, Newell-Price J, Findling JW, Gu F, Maldonado M, Sen K, Salgado LR, Colao A, Biller BM, Pasireotide B2305 Study Group) Clin Endocrinol (Oxf) 2014 Feb;80(2):261-9       91 Citations
1Sildenafil increases sympathetically mediated vascular tone in humans. (Dopp JM, Agapitov AV, Sinkey CA, Haynes WG, Phillips BG) Am J Hypertens 2013 Jun;26(6):762-9       14 Citations
1Effect of isoflavone soy protein supplementation on endometrial thickness, hyperplasia, and endometrial cancer risk in postmenopausal women: a randomized controlled trial. (Quaas AM, Kono N, Mack WJ, Hodis HN, Felix JC, Paulson RJ, Shoupe D) Menopause 2013 Aug;20(8):840-4    
2Randomized clinical trial evaluating intravitreal ranibizumab or saline for vitreous hemorrhage from proliferative diabetic retinopathy. (Diabetic Retinopathy Clinical Research Network*) JAMA Ophthalmol 2013 Mar;131(3):283-93       77 Citations
1Twelve-month efficacy and safety of 0.5 mg or 2.0 mg ranibizumab in patients with subfoveal neovascular age-related macular degeneration. (Busbee BG, Ho AC, Brown DM, Heier JS, Suñer IJ, Li Z, Rubio RG, Lai P, HARBOR Study Group) Ophthalmology 2013 May;120(5):1046-56       385 Citations
1Long-term efficacy of ustekinumab in patients with moderate-to-severe psoriasis treated for up to 5 years in the PHOENIX 1 study. (Kimball AB, Papp KA, Wasfi Y, Chan D, Bissonnette R, Sofen H, Yeilding N, Li S, Szapary P, Gordon KB, PHOENIX 1 Investigators) J Eur Acad Dermatol Venereol 2013 Dec;27(12):1535-45       169 Citations
1Decrease in high on-treatment platelet reactivity (HPR) prevalence on switching from clopidogrel to prasugrel: insights from the switching anti-platelet (SWAP) study. (Saucedo JF, Angiolillo DJ, DeRaad R, Frelinger AL 3rd, Gurbel PA, Costigan TM, Jakubowski JA, Ojeh CK, Duvvuru S, Effron MB, SWAP Investigators) Thromb Haemost 2013 Feb;109(2):347-55       21 Citations
2GKAP orchestrates activity-dependent postsynaptic protein remodeling and homeostatic scaling. (Shin SM, Zhang N, Hansen J, Gerges NZ, Pak DT, Sheng M, Lee SH) Nat Neurosci 2012 Dec;15(12):1655-66       99 Citations
2Comparison of the effectiveness of two protocols for treating nursing home residents with advanced dementia. (Kovach CR, Simpson MR, Joosse L, Logan BR, Noonan PE, Reynolds SA, Woods DL, Raff H) Res Gerontol Nurs 2012 Oct;5(4):251-63       20 Citations
1Association of impaired linear growth and worse neurodevelopmental outcome in infants with single ventricle physiology: a report from the pediatric heart network infant single ventricle trial. (Ravishankar C, Zak V, Williams IA, Bellinger DC, Gaynor JW, Ghanayem NS, Krawczeski CD, Licht DJ, Mahony L, Newburger JW, Pemberton VL, Williams RV, Sananes R, Cook AL, Atz T, Khaikin S, Hsu DT, Pediatric Heart Network Investigators) J Pediatr 2013 Feb;162(2):250-6.e2       101 Citations
1Effects of acute caloric restriction compared to caloric balance on the temporal response of the IGF-I system. (Henning PC, Scofield DE, Rarick KR, Pierce JR, Staab JS, Lieberman HR, Nindl BC) Metabolism 2013 Feb;62(2):179-87       23 Citations
1n-3 fatty acids and cardiovascular outcomes in patients with dysglycemia. (ORIGIN Trial Investigators, Bosch J, Gerstein HC, Dagenais GR, Díaz R, Dyal L, Jung H, Maggiono AP, Probstfield J, Ramachandran A, Riddle MC, Rydén LE, Yusuf S) N Engl J Med 2012 Jul 26;367(4):309-18       714 Citations
1Basal insulin and cardiovascular and other outcomes in dysglycemia. (ORIGIN Trial Investigators, Gerstein HC, Bosch J, Dagenais GR, Díaz R, Jung H, Maggioni AP, Pogue J, Probstfield J, Ramachandran A, Riddle MC, Rydén LE, Yusuf S) N Engl J Med 2012 Jul 26;367(4):319-28       1288 Citations
1Pharmacokinetic and pharmacodynamic effects of elinogrel: results of the platelet function substudy from the intravenous and oral administration of elinogrel to evaluate tolerability and efficacy in nonurgent percutaneous coronary intervention patients (INNOVATE-PCI) trial. (Angiolillo DJ, Welsh RC, Trenk D, Neumann FJ, Conley PB, McClure MW, Stephens G, Kochman J, Jennings LK, Gurbel PA, Wójcik J, Dabrowski M, Saucedo JF, Stumpf J, Buerke M, Broderick S, Harrington RA, Rao SV) Circ Cardiovasc Interv 2012 Jun;5(3):347-56       30 Citations
2Lenalidomide after stem-cell transplantation for multiple myeloma. (McCarthy PL, Owzar K, Hofmeister CC, Hurd DD, Hassoun H, Richardson PG, Giralt S, Stadtmauer EA, Weisdorf DJ, Vij R, Moreb JS, Callander NS, Van Besien K, Gentile T, Isola L, Maziarz RT, Gabriel DA, Bashey A, Landau H, Martin T, Qazilbash MH, Levitan D, McClune B, Schlossman R, Hars V, Postiglione J, Jiang C, Bennett E, Barry S, Bressler L, Kelly M, Seiler M, Rosenbaum C, Hari P, Pasquini MC, Horowitz MM, Shea TC, Devine SM, Anderson KC, Linker C) N Engl J Med 2012 May 10;366(19):1770-81    
1Effect of sulfasalazine on inflammation and endothelial function in patients with established coronary artery disease. (Tabit CE, Holbrook M, Shenouda SM, Dohadwala MM, Widlansky ME, Frame AA, Kim BH, Duess MA, Kluge MA, Levit A, Keaney JF Jr, Vita JA, Hamburg NM) Vasc Med 2012 Apr;17(2):101-7       18 Citations
1Out-of-hospital administration of intravenous glucose-insulin-potassium in patients with suspected acute coronary syndromes: the IMMEDIATE randomized controlled trial. (Selker HP, Beshansky JR, Sheehan PR, Massaro JM, Griffith JL, D'Agostino RB, Ruthazer R, Atkins JM, Sayah AJ, Levy MK, Richards ME, Aufderheide TP, Braude DA, Pirrallo RG, Doyle DD, Frascone RJ, Kosiak DJ, Leaming JM, Van Gelder CM, Walter GP, Wayne MA, Woolard RH, Opie LH, Rackley CE, Apstein CS, Udelson JE) JAMA 2012 May 09;307(18):1925-33       173 Citations
1Effect of transendocardial delivery of autologous bone marrow mononuclear cells on functional capacity, left ventricular function, and perfusion in chronic heart failure: the FOCUS-CCTRN trial. (Perin EC, Willerson JT, Pepine CJ, Henry TD, Ellis SG, Zhao DX, Silva GV, Lai D, Thomas JD, Kronenberg MW, Martin AD, Anderson RD, Traverse JH, Penn MS, Anwaruddin S, Hatzopoulos AK, Gee AP, Taylor DA, Cogle CR, Smith D, Westbrook L, Chen J, Handberg E, Olson RE, Geither C, Bowman S, Francescon J, Baraniuk S, Piller LB, Simpson LM, Loghin C, Aguilar D, Richman S, Zierold C, Bettencourt J, Sayre SL, Vojvodic RW, Skarlatos SI, Gordon DJ, Ebert RF, Kwak M, Moyé LA, Simari RD, Cardiovascular Cell Therapy Research Network (CCTRN)) JAMA 2012 Apr 25;307(16):1717-26       382 Citations
1A double-blind, placebo-controlled, randomized, clinical trial of the TLR-3 agonist rintatolimod in severe cases of chronic fatigue syndrome. (Strayer DR, Carter WA, Stouch BC, Stevens SR, Bateman L, Cimoch PJ, Lapp CW, Peterson DL, Chronic Fatigue Syndrome AMP-516 Study Group, Mitchell WM) PLoS One 2012;7(3):e31334       61 Citations
1Study design for the Immediate Myocardial Metabolic Enhancement During Initial Assessment and Treatment in Emergency Care (IMMEDIATE) Trial: A double-blind randomized controlled trial of intravenous glucose, insulin, and potassium for acute coronary syndromes in emergency medical services. (Selker HP, Beshansky JR, Griffith JL, D'Agostino RB, Massaro JM, Udelson JE, Rashba EJ, Ruthazer R, Sheehan PR, Desvigne-Nickens P, Rosenberg YD, Atkins JM, Sayah AJ, Aufderheide TP, Rackley CE, Opie LH, Lambrew CT, Cobb LA, Macleod BA, Ingwall JS, Zalenski RJ, Apstein CS) Am Heart J 2012 Mar;163(3):315-22       22 Citations
1A 12-month phase 3 study of pasireotide in Cushing's disease. (Colao A, Petersenn S, Newell-Price J, Findling JW, Gu F, Maldonado M, Schoenherr U, Mills D, Salgado LR, Biller BM, Pasireotide B2305 Study Group) N Engl J Med 2012 Mar 08;366(10):914-24    
1An update on the long-term safety experience of ustekinumab: results from the psoriasis clinical development program with up to four years of follow-up. (Reich K, Papp KA, Griffiths CE, Szapary PO, Yeilding N, Wasfi Y, Ott E, Hsu MC, Lebwohl M, Gordon KB, PHOENIX 1, PHOENIX 2, and ACCEPT investigators) J Drugs Dermatol 2012 Mar;11(3):300-12       72 Citations
1Long-term efficacy of ustekinumab in patients with moderate-to-severe psoriasis: results from the PHOENIX 1 trial through up to 3 years. (Kimball AB, Gordon KB, Fakharzadeh S, Yeilding N, Szapary PO, Schenkel B, Guzzo C, Li S, Papp KA) Br J Dermatol 2012 Apr;166(4):861-72       117 Citations
1Intramuscular versus intravenous therapy for prehospital status epilepticus. (Silbergleit R, Durkalski V, Lowenstein D, Conwit R, Pancioli A, Palesch Y, Barsan W, NETT Investigators) N Engl J Med 2012 Feb 16;366(7):591-600    
1Factors affecting the turnaround time for manufacturing, testing, and release of cellular therapy products prepared at multiple sites in support of multicenter cardiovascular regenerative medicine protocols: a Cardiovascular Cell Therapy Research Network (CCTRN) study. (Richman S, Gee AP, McKenna DH, Traverse JH, Henry TD, Fisk D, Pepine CJ, Bloom J, Willerson JT, Prater K, Zhao D, Koç JR, Anwaruddin S, Taylor DA, Cogle CR, Moyé LA, Simari RD, Skarlatos SI) Transfusion 2012 Oct;52(10):2225-33       4 Citations
1Accuracy of pain recall in children. (Chogle A, Sztainberg M, Bass L, Youssef NN, Miranda A, Nurko S, Hyman P, Cocjin J, Di Lorenzo C, Saps M) J Pediatr Gastroenterol Nutr 2012 Sep;55(3):288-91       32 Citations
1Vitamin D3 decreases parathyroid hormone in HIV-infected youth being treated with tenofovir: a randomized, placebo-controlled trial. (Havens PL, Stephensen CB, Hazra R, Flynn PM, Wilson CM, Rutledge B, Bethel J, Pan CG, Woodhouse LR, Van Loan MD, Liu N, Lujan-Zilbermann J, Baker A, Kapogiannis BG, Mulligan K, Adolescent Medicine Trials Network (ATN) for HIV/AIDS Interventions 063 study team) Clin Infect Dis 2012 Apr;54(7):1013-25       57 Citations
1Usefulness of heart rate to predict cardiac events in treated patients with high-risk systemic hypertension. (Julius S, Palatini P, Kjeldsen SE, Zanchetti A, Weber MA, McInnes GT, Brunner HR, Mancia G, Schork MA, Hua TA, Holzhauer B, Zappe D, Majahalme S, Jamerson K, Koylan N) Am J Cardiol 2012 Mar 01;109(5):685-92       108 Citations
1Triple-blind randomized clinical trial of time until sensory change using 1.5% mepivacaine with epinephrine, 0.5% bupivacaine, or an equal mixture of both for infraclavicular block. (Laur JJ, Bayman EO, Foldes PJ, Rosenquist RW) Reg Anesth Pain Med 2012;37(1):28-33       16 Citations
1Pyridorin in type 2 diabetic nephropathy. (Lewis EJ, Greene T, Spitalewiz S, Blumenthal S, Berl T, Hunsicker LG, Pohl MA, Rohde RD, Raz I, Yerushalmy Y, Yagil Y, Herskovits T, Atkins RC, Reutens AT, Packham DK, Lewis JB, Collaborative Study Group) J Am Soc Nephrol 2012 Jan;23(1):131-6       123 Citations
1A phase III, randomized, controlled trial of the fully human IL-12/23 mAb briakinumab in moderate-to-severe psoriasis. (Gordon KB, Langley RG, Gottlieb AB, Papp KA, Krueger GG, Strober BE, Williams DA, Gu Y, Valdes JM) J Invest Dermatol 2012 Feb;132(2):304-14       141 Citations
1Long-term safety experience of ustekinumab in patients with moderate to severe psoriasis (Part II of II): results from analyses of infections and malignancy from pooled phase II and III clinical trials. (Gordon KB, Papp KA, Langley RG, Ho V, Kimball AB, Guzzo C, Yeilding N, Szapary PO, Fakharzadeh S, Li S, Hsu MC, Reich K) J Am Acad Dermatol 2012 May;66(5):742-51       116 Citations
1Changes in vision- and health-related quality of life in patients with diabetic macular edema treated with pegaptanib sodium or sham. (Loftus JV, Sultan MB, Pleil AM, Macugen 1013 Study Group) Invest Ophthalmol Vis Sci 2011 Sep 29;52(10):7498-505       29 Citations
1Association between biologic therapies for chronic plaque psoriasis and cardiovascular events: a meta-analysis of randomized controlled trials. (Ryan C, Leonardi CL, Krueger JG, Kimball AB, Strober BE, Gordon KB, Langley RG, de Lemos JA, Daoud Y, Blankenship D, Kazi S, Kaplan DH, Friedewald VE, Menter A) JAMA 2011 Aug 24;306(8):864-71       250 Citations
1Efficacy and tolerability of once-weekly rosuvastatin in patients with previous statin intolerance. (Kennedy SP, Barnas GP, Schmidt MJ, Glisczinski MS, Paniagua AC) J Clin Lipidol 2011;5(4):308-15       40 Citations
1A prospective randomized double-blinded pilot study to examine the effect of botulinum toxin type A injection versus Lidocaine/Depomedrol injection on residual and phantom limb pain: initial report. (Wu H, Sultana R, Taylor KB, Szabo A) Clin J Pain 2012 Feb;28(2):108-12       50 Citations
3Amelioration of oral mucositis pain by NASA near-infrared light-emitting diodes in bone marrow transplant patients. (Hodgson BD, Margolis DM, Salzman DE, Eastwood D, Tarima S, Williams LD, Sande JE, Vaughan WP, Whelan HT) Support Care Cancer 2012 Jul;20(7):1405-15       49 Citations
1Renin-angiotensin-aldosterone genotype influences ventricular remodeling in infants with single ventricle. (Mital S, Chung WK, Colan SD, Sleeper LA, Manlhiot C, Arrington CB, Cnota JF, Graham EM, Mitchell ME, Goldmuntz E, Li JS, Levine JC, Lee TM, Margossian R, Hsu DT, Pediatric Heart Network Investigators) Circulation 2011 May 31;123(21):2353-62       54 Citations
1Test-retest reliability of memory task functional magnetic resonance imaging in Alzheimer disease clinical trials. (Atri A, O'Brien JL, Sreenivasan A, Rastegar S, Salisbury S, DeLuca AN, O'Keefe KM, LaViolette PS, Rentz DM, Locascio JJ, Sperling RA) Arch Neurol 2011 May;68(5):599-606       30 Citations
1Health outcomes after stopping conjugated equine estrogens among postmenopausal women with prior hysterectomy: a randomized controlled trial. (LaCroix AZ, Chlebowski RT, Manson JE, Aragaki AK, Johnson KC, Martin L, Margolis KL, Stefanick ML, Brzyski R, Curb JD, Howard BV, Lewis CE, Wactawski-Wende J, WHI Investigators) JAMA 2011 Apr 06;305(13):1305-14       489 Citations
1Riluzole decreases flexion withdrawal reflex but not voluntary ankle torque in human chronic spinal cord injury. (Theiss RD, Hornby TG, Rymer WZ, Schmit BD) J Neurophysiol 2011 Jun;105(6):2781-90       18 Citations
7The effect of caudal vs intravenous morphine on early extubation and postoperative analgesic requirements for stage 2 and 3 single-ventricle palliation: a double blind randomized trial. (Stuth EA, Berens RJ, Staudt SR, Robertson FA, Scott JP, Stucke AG, Hoffman GM, Troshynski TJ, Tweddell JS, Zuperku EJ) Paediatr Anaesth 2011 Apr;21(4):441-53       19 Citations
1A multi-site study using high-resolution HLA genotyping by next generation sequencing. (Holcomb CL, Höglund B, Anderson MW, Blake LA, Böhme I, Egholm M, Ferriola D, Gabriel C, Gelber SE, Goodridge D, Hawbecker S, Klein R, Ladner M, Lind C, Monos D, Pando MJ, Pröll J, Sayer DC, Schmitz-Agheguian G, Simen BB, Thiele B, Trachtenberg EA, Tyan DB, Wassmuth R, White S, Erlich HA) Tissue Antigens 2011 Mar;77(3):206-17       99 Citations
1A pharmacodynamic comparison of prasugrel vs. high-dose clopidogrel in patients with type 2 diabetes mellitus and coronary artery disease: results of the Optimizing anti-Platelet Therapy In diabetes MellitUS (OPTIMUS)-3 Trial. (Angiolillo DJ, Badimon JJ, Saucedo JF, Frelinger AL, Michelson AD, Jakubowski JA, Zhu B, Ojeh CK, Baker BA, Effron MB) Eur Heart J 2011 Apr;32(7):838-46       173 Citations
1Cortisol's effects on hippocampal activation in depressed patients are related to alterations in memory formation. (Abercrombie HC, Jahn AL, Davidson RJ, Kern S, Kirschbaum C, Halverson J) J Psychiatr Res 2011 Jan;45(1):15-23       45 Citations
1Out-of-hospital hypertonic resuscitation after traumatic hypovolemic shock: a randomized, placebo controlled trial. (Bulger EM, May S, Kerby JD, Emerson S, Stiell IG, Schreiber MA, Brasel KJ, Tisherman SA, Coimbra R, Rizoli S, Minei JP, Hata JS, Sopko G, Evans DC, Hoyt DB, ROC investigators) Ann Surg 2011 Mar;253(3):431-41       219 Citations
2Out-of-hospital hypertonic resuscitation following severe traumatic brain injury: a randomized controlled trial. (Bulger EM, May S, Brasel KJ, Schreiber M, Kerby JD, Tisherman SA, Newgard C, Slutsky A, Coimbra R, Emerson S, Minei JP, Bardarson B, Kudenchuk P, Baker A, Christenson J, Idris A, Davis D, Fabian TC, Aufderheide TP, Callaway C, Williams C, Banek J, Vaillancourt C, van Heest R, Sopko G, Hata JS, Hoyt DB, ROC Investigators) JAMA 2010 Oct 06;304(13):1455-64       204 Citations
1Increased platelet inhibition after switching from maintenance clopidogrel to prasugrel in patients with acute coronary syndromes: results of the SWAP (SWitching Anti Platelet) study. (Angiolillo DJ, Saucedo JF, Deraad R, Frelinger AL, Gurbel PA, Costigan TM, Jakubowski JA, Ojeh CK, Effron MB, SWAP Investigators) J Am Coll Cardiol 2010 Sep 21;56(13):1017-23       160 Citations
1Endometrial effect of progesterone delivered by vaginal rings in estrogen-treated postmenopausal women. (Noé G, Sitruk-Ware R, Zegers-Hochschild F, Variano B, Montero JC, Arriagada P, Li A, Stanczyk FZ, Felix JC, Mishell DR, Croxatto HB) Climacteric 2010 Oct;13(5):433-41       7 Citations
1Enalapril in infants with single ventricle: results of a multicenter randomized trial. (Hsu DT, Zak V, Mahony L, Sleeper LA, Atz AM, Levine JC, Barker PC, Ravishankar C, McCrindle BW, Williams RV, Altmann K, Ghanayem NS, Margossian R, Chung WK, Border WL, Pearson GD, Stylianou MP, Mital S, Pediatric Heart Network Investigators) Circulation 2010 Jul 27;122(4):333-40       244 Citations
1Efficacy and safety of adalimumab across subgroups of patients with moderate to severe psoriasis. (Menter A, Gordon KB, Leonardi CL, Gu Y, Goldblum OM) J Am Acad Dermatol 2010 Sep;63(3):448-56       127 Citations
1Ustekinumab significantly improves symptoms of anxiety, depression, and skin-related quality of life in patients with moderate-to-severe psoriasis: Results from a randomized, double-blind, placebo-controlled phase III trial. (Langley RG, Feldman SR, Han C, Schenkel B, Szapary P, Hsu MC, Ortonne JP, Gordon KB, Kimball AB) J Am Acad Dermatol 2010 Sep;63(3):457-65       164 Citations
2Randomized trial evaluating ranibizumab plus prompt or deferred laser or triamcinolone plus prompt laser for diabetic macular edema. (Diabetic Retinopathy Clinical Research Network, Elman MJ, Aiello LP, Beck RW, Bressler NM, Bressler SB, Edwards AR, Ferris FL 3rd, Friedman SM, Glassman AR, Miller KM, Scott IU, Stockdale CR, Sun JK) Ophthalmology 2010 Jun;117(6):1064-1077.e35       1148 Citations
7Gabapentin use in pediatric spinal fusion patients: a randomized, double-blind, controlled trial. (Rusy LM, Hainsworth KR, Nelson TJ, Czarnecki ML, Tassone JC, Thometz JG, Lyon RM, Berens RJ, Weisman SJ) Anesth Analg 2010 May 01;110(5):1393-8       113 Citations
1Randomized controlled trial of atorvastatin in mild to moderate Alzheimer disease: LEADe. (Feldman HH, Doody RS, Kivipelto M, Sparks DL, Waters DD, Jones RW, Schwam E, Schindler R, Hey-Hadavi J, DeMicco DA, Breazna A, LEADe Investigators) Neurology 2010 Mar 23;74(12):956-64       329 Citations
1A prospective, randomized trial of intravenous prochlorperazine versus subcutaneous sumatriptan in acute migraine therapy in the emergency department. (Kostic MA, Gutierrez FJ, Rieg TS, Moore TS, Gendron RT) Ann Emerg Med 2010 Jul;56(1):1-6       54 Citations
1Oestrogen plus progestin and lung cancer in postmenopausal women (Women's Health Initiative trial): a post-hoc analysis of a randomised controlled trial. (Chlebowski RT, Schwartz AG, Wakelee H, Anderson GL, Stefanick ML, Manson JE, Rodabough RJ, Chien JW, Wactawski-Wende J, Gass M, Kotchen JM, Johnson KC, O'Sullivan MJ, Ockene JK, Chen C, Hubbell FA, Women's Health Initiative Investigators) Lancet 2009 Oct 10;374(9697):1243-51       249 Citations
2A randomized clinical trial of ibuprofen versus acetaminophen with codeine for acute pediatric arm fracture pain. (Drendel AL, Gorelick MH, Weisman SJ, Lyon R, Brousseau DC, Kim MK) Ann Emerg Med 2009 Oct;54(4):553-60       122 Citations
1Randomized double-blind phase II trial comparing gemcitabine plus LY293111 versus gemcitabine plus placebo in advanced adenocarcinoma of the pancreas. (Saif MW, Oettle H, Vervenne WL, Thomas JP, Spitzer G, Visseren-Grul C, Enas N, Richards DA) Cancer J 2009;15(4):339-43       42 Citations
1Effect of ingested interferon-alpha on beta-cell function in children with new-onset type 1 diabetes. (Rother KI, Brown RJ, Morales MM, Wright E, Duan Z, Campbell C, Hardin DS, Popovic J, McEvoy RC, Harlan DM, Orlander PR, Brod SA) Diabetes Care 2009 Jul;32(7):1250-5       36 Citations
1Pegaptanib sodium for macular edema secondary to central retinal vein occlusion. (Wroblewski JJ, Wells JA 3rd, Adamis AP, Buggage RR, Cunningham ET Jr, Goldbaum M, Guyer DR, Katz B, Altaweel MM, Pegaptanib in Central Retinal Vein Occlusion Study Group) Arch Ophthalmol 2009 Apr;127(4):374-80       83 Citations
1Pediatric Atorvastatin in Diabetes Trial (PADIT): a pilot study to determine the effect of atorvastatin on arterial stiffness and endothelial function in children with type 1 diabetes mellitus. (Haller MJ, Stein JM, Shuster JJ, Theriaque D, Samyn MM, Pepine C, Silverstein JH) J Pediatr Endocrinol Metab 2009 Jan;22(1):65-8       36 Citations
1Recombinant human relaxin in the treatment of systemic sclerosis with diffuse cutaneous involvement: a randomized, double-blind, placebo-controlled trial. (Khanna D, Clements PJ, Furst DE, Korn JH, Ellman M, Rothfield N, Wigley FM, Moreland LW, Silver R, Kim YH, Steen VD, Firestein GS, Kavanaugh AF, Weisman M, Mayes MD, Collier D, Csuka ME, Simms R, Merkel PA, Medsger TA Jr, Sanders ME, Maranian P, Seibold JR, Relaxin Investigators and the Scleroderma Clinical Trials Consortium) Arthritis Rheum 2009 Apr;60(4):1102-11       110 Citations
1Randomized, double-blind, placebo-controlled trial of effects of enteral iron supplementation on anemia and risk of infection during surgical critical illness. (Pieracci FM, Henderson P, Rodney JR, Holena DN, Genisca A, Ip I, Benkert S, Hydo LJ, Eachempati SR, Shou J, Barie PS) Surg Infect (Larchmt) 2009 Feb;10(1):9-19       66 Citations
1MQX-503, a novel formulation of nitroglycerin, improves the severity of Raynaud's phenomenon: a randomized, controlled trial. (Chung L, Shapiro L, Fiorentino D, Baron M, Shanahan J, Sule S, Hsu V, Rothfield N, Steen V, Martin RW, Smith E, Mayes M, Simms R, Pope J, Kahaleh B, Csuka ME, Gruber B, Collier D, Sweiss N, Gilbert A, Dechow FJ, Gregory J, Wigley FM) Arthritis Rheum 2009 Mar;60(3):870-7       83 Citations
1Improved vision-related function after ranibizumab vs photodynamic therapy: a randomized clinical trial. (Bressler NM, Chang TS, Fine JT, Dolan CM, Ward J, Anti-VEGF Antibody for the Treatment of Predominantly Classic Choroidal Neovascularization in Age-Related Macular Degeneration (ANCHOR) Research Group) Arch Ophthalmol 2009 Jan;127(1):13-21       85 Citations
1Ranibizumab versus verteporfin photodynamic therapy for neovascular age-related macular degeneration: Two-year results of the ANCHOR study. (Brown DM, Michels M, Kaiser PK, Heier JS, Sy JP, Ianchulev T, ANCHOR Study Group) Ophthalmology 2009 Jan;116(1):57-65.e5       1112 Citations
1Rationale and design of a trial of angiotensin-converting enzyme inhibition in infants with single ventricle. (Hsu DT, Mital S, Ravishankar C, Margossian R, Li JS, Sleeper LA, Williams RV, Levine JC, McCrindle BW, Atz AM, Servedio D, Mahony L, Pediatric Heart Network Investigators) Am Heart J 2009 Jan;157(1):37-45       33 Citations
1Subcutaneous IGF-1 is not beneficial in 2-year ALS trial. (Sorenson EJ, Windbank AJ, Mandrekar JN, Bamlet WR, Appel SH, Armon C, Barkhaus PE, Bosch P, Boylan K, David WS, Feldman E, Glass J, Gutmann L, Katz J, King W, Luciano CA, McCluskey LF, Nash S, Newman DS, Pascuzzi RM, Pioro E, Sams LJ, Scelsa S, Simpson EP, Subramony SH, Tiryaki E, Thornton CA) Neurology 2008 Nov 25;71(22):1770-5       208 Citations
1Growth hormone secretagogue MK-677: no clinical effect on AD progression in a randomized trial. (Sevigny JJ, Ryan JM, van Dyck CH, Peng Y, Lines CR, Nessly ML, MK-677 Protocol 30 Study Group) Neurology 2008 Nov 18;71(21):1702-8       70 Citations
1Gastrointestinal tract recovery in patients undergoing bowel resection: results of a randomized trial of alvimopan and placebo with a standardized accelerated postoperative care pathway. (Ludwig K, Enker WE, Delaney CP, Wolff BG, Du W, Fort JG, Cherubini M, Cucinotta J, Techner L) Arch Surg 2008 Nov;143(11):1098-105       124 Citations
1Calcium plus vitamin D supplementation and the risk of breast cancer. (Chlebowski RT, Johnson KC, Kooperberg C, Pettinger M, Wactawski-Wende J, Rohan T, Rossouw J, Lane D, O'Sullivan MJ, Yasmeen S, Hiatt RA, Shikany JM, Vitolins M, Khandekar J, Hubbell FA, Women's Health Initiative Investigators) J Natl Cancer Inst 2008 Nov 19;100(22):1581-91       363 Citations
1Palate implants for obstructive sleep apnea: multi-institution, randomized, placebo-controlled study. (Steward DL, Huntley TC, Woodson BT, Surdulescu V) Otolaryngol Head Neck Surg 2008 Oct;139(4):506-10       51 Citations
1Conjugated equine estrogens and colorectal cancer incidence and survival: the Women's Health Initiative randomized clinical trial. (Ritenbaugh C, Stanford JL, Wu L, Shikany JM, Schoen RE, Stefanick ML, Taylor V, Garland C, Frank G, Lane D, Mason E, McNeeley SG, Ascensao J, Chlebowski RT, Women's Health Initiative Investigators) Cancer Epidemiol Biomarkers Prev 2008 Oct;17(10):2609-18       80 Citations
1Treatment of acute postoperative hypertension in cardiac surgery patients: an efficacy study of clevidipine assessing its postoperative antihypertensive effect in cardiac surgery-2 (ESCAPE-2), a randomized, double-blind, placebo-controlled trial. (Singla N, Warltier DC, Gandhi SD, Lumb PD, Sladen RN, Aronson S, Newman MF, Corwin HL, ESCAPE-2 Study Group) Anesth Analg 2008 Jul;107(1):59-67       87 Citations
1Medication of l-tetrahydropalmatine significantly ameliorates opiate craving and increases the abstinence rate in heroin users: a pilot study. (Yang Z, Shao YC, Li SJ, Qi JL, Zhang MJ, Hao W, Jin GZ) Acta Pharmacol Sin 2008 Jul;29(7):781-8       61 Citations
1Resuscitation Outcomes Consortium (ROC) PRIMED cardiac arrest trial methods part 1: rationale and methodology for the impedance threshold device (ITD) protocol. (Aufderheide TP, Kudenchuk PJ, Hedges JR, Nichol G, Kerber RE, Dorian P, Davis DP, Idris AH, Callaway CW, Emerson S, Stiell IG, Terndrup TE, ROC Investigators) Resuscitation 2008 Aug;78(2):179-85       44 Citations
1Efficacy and safety of ustekinumab, a human interleukin-12/23 monoclonal antibody, in patients with psoriasis: 52-week results from a randomised, double-blind, placebo-controlled trial (PHOENIX 2). (Papp KA, Langley RG, Lebwohl M, Krueger GG, Szapary P, Yeilding N, Guzzo C, Hsu MC, Wang Y, Li S, Dooley LT, Reich K, PHOENIX 2 study investigators) Lancet 2008 May 17;371(9625):1675-84       1266 Citations
1Efficacy and safety of ustekinumab, a human interleukin-12/23 monoclonal antibody, in patients with psoriasis: 76-week results from a randomised, double-blind, placebo-controlled trial (PHOENIX 1). (Leonardi CL, Kimball AB, Papp KA, Yeilding N, Guzzo C, Wang Y, Li S, Dooley LT, Gordon KB, PHOENIX 1 study investigators) Lancet 2008 May 17;371(9625):1665-74       1416 Citations
1Predicting response of vitreous hemorrhage after intravitreous injection of highly purified ovine hyaluronidase (Vitrase) in patients with diabetes. (Bhavsar AR, Grillone LR, McNamara TR, Gow JA, Hochberg AM, Pearson RK, Vitrase for Vitreous Hemorrhage Study Groups) Invest Ophthalmol Vis Sci 2008 Oct;49(10):4219-25       9 Citations
1Ibuprofen and paracetamol for pain relief during medical abortion: a double-blind randomized controlled study. (Livshits A, Machtinger R, David LB, Spira M, Moshe-Zahav A, Seidman DS) Fertil Steril 2009 May;91(5):1877-80       51 Citations
1Impact of adalimumab treatment on patient-reported outcomes: results from a Phase III clinical trial in patients with moderate to severe plaque psoriasis. (Revicki DA, Willian MK, Menter A, Gordon KB, Kimball AB, Leonardi CL, Langley RG, Kimel M, Okun M) J Dermatolog Treat 2007;18(6):341-50       87 Citations
2Feasibility of auditory cortical stimulation for the treatment of tinnitus. (Friedland DR, Gaggl W, Runge-Samuelson C, Ulmer JL, Kopell BH) Otol Neurotol 2007 Dec;28(8):1005-12       63 Citations
1Improved vision-related function after ranibizumab treatment of neovascular age-related macular degeneration: results of a randomized clinical trial. (Chang TS, Bressler NM, Fine JT, Dolan CM, Ward J, Klesert TR, MARINA Study Group) Arch Ophthalmol 2007 Nov;125(11):1460-9       200 Citations
1Adalimumab therapy for moderate to severe psoriasis: A randomized, controlled phase III trial. (Menter A, Tyring SK, Gordon K, Kimball AB, Leonardi CL, Langley RG, Strober BE, Kaul M, Gu Y, Okun M, Papp K) J Am Acad Dermatol 2008 Jan;58(1):106-15       757 Citations
1Effect of prophylactic ondansetron on postoperative nausea and vomiting in patients on preoperative steroids undergoing craniotomy for supratentorial tumors. (Wig J, Chandrashekharappa KN, Yaddanapudi LN, Nakra D, Mukherjee KK) J Neurosurg Anesthesiol 2007 Oct;19(4):239-42       18 Citations
1Targeting TNFalpha rapidly reduces density of dendritic cells and macrophages in psoriatic plaques with restoration of epidermal keratinocyte differentiation. (Marble DJ, Gordon KB, Nickoloff BJ) J Dermatol Sci 2007 Nov;48(2):87-101       52 Citations
1Angiographic and optical coherence tomographic results of the MARINA study of ranibizumab in neovascular age-related macular degeneration. (Kaiser PK, Blodi BA, Shapiro H, Acharya NR, MARINA Study Group) Ophthalmology 2007 Oct;114(10):1868-75       189 Citations
1Effect of mifepristone on endometrial matrix metalloproteinase expression and leukocyte abundance in new medroxyprogesterone acetate users. (Li A, Felix JC, Yang W, Xiong DW, Minoo P, Jain JK) Contraception 2007 Jul;76(1):57-65       15 Citations
1Neurodevelopmental outcomes of premature infants with severe respiratory failure enrolled in a randomized controlled trial of inhaled nitric oxide. (Hintz SR, Van Meurs KP, Perritt R, Poole WK, Das A, Stevenson DK, Ehrenkranz RA, Lemons JA, Vohr BR, Heyne R, Childers DO, Peralta-Carcelen M, Dusick A, Johnson YR, Morris B, Dillard R, Vaucher Y, Steichen J, Adams-Chapman I, Konduri G, Myers GJ, de Ungria M, Tyson JE, Higgins RD, NICHD Neonatal Research Network) J Pediatr 2007 Jul;151(1):16-22, 22.e1-3       52 Citations
1A double-blind, placebo-controlled, dose-response pilot study evaluating intradiscal etanercept in patients with chronic discogenic low back pain or lumbosacral radiculopathy. (Cohen SP, Wenzell D, Hurley RW, Kurihara C, Buckenmaier CC 3rd, Griffith S, Larkin TM, Dahl E, Morlando BJ) Anesthesiology 2007 Jul;107(1):99-105       84 Citations
1Long-term safety and efficacy of 50 mg of etanercept twice weekly in patients with psoriasis. (Tyring S, Gordon KB, Poulin Y, Langley RG, Gottlieb AB, Dunn M, Jahreis A) Arch Dermatol 2007 Jun;143(6):719-26       304 Citations
1Impact of randomized clinical trial results in the national comprehensive cancer network on the use of tamoxifen after breast surgery for ductal carcinoma in situ. (Yen TW, Kuerer HM, Ottesen RA, Rouse L, Niland JC, Edge SB, Theriault RL, Weeks JC) J Clin Oncol 2007 Aug 01;25(22):3251-8       45 Citations
1Suppression of bone density loss and bone turnover in patients with hormone-sensitive prostate cancer and receiving zoledronic acid. (Ryan CW, Huo D, Bylow K, Demers LM, Stadler WM, Henderson TO, Vogelzang NJ) BJU Int 2007 Jul;100(1):70-5       50 Citations
1Acute EGCG supplementation reverses endothelial dysfunction in patients with coronary artery disease. (Widlansky ME, Hamburg NM, Anter E, Holbrook M, Kahn DF, Elliott JG, Keaney JF Jr, Vita JA) J Am Coll Nutr 2007 Apr;26(2):95-102       186 Citations
1Volume replacement therapy during major orthopedic surgery using Voluven (hydroxyethyl starch 130/0.4) or hetastarch. (Gandhi SD, Weiskopf RB, Jungheinrich C, Koorn R, Miller D, Shangraw RE, Prough DS, Baus D, Bepperling F, Warltier DC) Anesthesiology 2007 Jun;106(6):1120-7       87 Citations
1Clinical models that objectively evaluate interproximal plaque based on total protein concentration. (Milanovich N, Souza SM, de Jager M, Hefti AF) J Clin Periodontol 2007 Jun;34(6):499-506       2 Citations
1Results from a phase II multicenter, double-blind placebo-controlled study of Del-1 (VLTS-589) for intermittent claudication in subjects with peripheral arterial disease. (Grossman PM, Mendelsohn F, Henry TD, Hermiller JB, Litt M, Saucedo JF, Weiss RJ, Kandzari DE, Kleiman N, Anderson RD, Gottlieb D, Karlsberg R, Snell J, Rocha-Singh K) Am Heart J 2007 May;153(5):874-80       75 Citations
1Effect of combined treatment with alpha-Lipoic acid and acetyl-L-carnitine on vascular function and blood pressure in patients with coronary artery disease. (McMackin CJ, Widlansky ME, Hamburg NM, Huang AL, Weller S, Holbrook M, Gokce N, Hagen TM, Keaney JF Jr, Vita JA) J Clin Hypertens (Greenwich) 2007 Apr;9(4):249-55       85 Citations
1Postoperative ileus-related morbidity profile in patients treated with alvimopan after bowel resection. (Wolff BG, Weese JL, Ludwig KA, Delaney CP, Stamos MJ, Michelassi F, Du W, Techner L) J Am Coll Surg 2007 Apr;204(4):609-16       56 Citations
1Randomized controlled study of an intravitreous dexamethasone drug delivery system in patients with persistent macular edema. (Kuppermann BD, Blumenkranz MS, Haller JA, Williams GA, Weinberg DV, Chou C, Whitcup SM, Dexamethasone DDS Phase II Study Group) Arch Ophthalmol 2007 Mar;125(3):309-17       370 Citations
1Early inhaled nitric oxide therapy for term and near-term newborn infants with hypoxic respiratory failure: neurodevelopmental follow-up. (Konduri GG, Vohr B, Robertson C, Sokol GM, Solimano A, Singer J, Ehrenkranz RA, Singhal N, Wright LL, Van Meurs K, Stork E, Kirpalani H, Peliowski A, Johnson Y, Neonatal Inhaled Nitric Oxide Study Group) J Pediatr 2007 Mar;150(3):235-40, 240.e1       78 Citations
1Subgroup analysis of the MARINA study of ranibizumab in neovascular age-related macular degeneration. (Boyer DS, Antoszyk AN, Awh CC, Bhisitkul RB, Shapiro H, Acharya NR, MARINA Study Group) Ophthalmology 2007 Feb;114(2):246-52       349 Citations
1Mifepristone alters expression of endometrial steroid receptors and their cofactors in new users of medroxyprogesterone acetate. (Jain JK, Li A, Yang W, Minoo P, Felix JC) Fertil Steril 2007 Jan;87(1):8-23       9 Citations
1Risperidone in preschool children with autistic spectrum disorders: an investigation of safety and efficacy. (Luby J, Mrakotsky C, Stalets MM, Belden A, Heffelfinger A, Williams M, Spitznagel E) J Child Adolesc Psychopharmacol 2006 Oct;16(5):575-87       122 Citations
1Ranibizumab versus verteporfin for neovascular age-related macular degeneration. (Brown DM, Kaiser PK, Michels M, Soubrane G, Heier JS, Kim RY, Sy JP, Schneider S, ANCHOR Study Group) N Engl J Med 2006 Oct 05;355(14):1432-44       3040 Citations
1Clinical response to adalimumab treatment in patients with moderate to severe psoriasis: double-blind, randomized controlled trial and open-label extension study. (Gordon KB, Langley RG, Leonardi C, Toth D, Menter MA, Kang S, Heffernan M, Miller B, Hamlin R, Lim L, Zhong J, Hoffman R, Okun MM) J Am Acad Dermatol 2006 Oct;55(4):598-606       463 Citations
1Effects of the Serial Trial Intervention on discomfort and behavior of nursing home residents with dementia. (Kovach CR, Logan BR, Noonan PE, Schlidt AM, Smerz J, Simpson M, Wells T) Am J Alzheimers Dis Other Demen 2006;21(3):147-55       116 Citations
1The Valsartan Antihypertensive Long-Term Use Evaluation (VALUE) trial: outcomes in patients receiving monotherapy. (Julius S, Weber MA, Kjeldsen SE, McInnes GT, Zanchetti A, Brunner HR, Laragh J, Schork MA, Hua TA, Amerena J, Balazovjech I, Cassel G, Herczeg B, Koylan N, Magometschnigg D, Majahalme S, Martinez F, Oigman W, Seabra Gomes R, Zhu JR) Hypertension 2006 Sep;48(3):385-91       128 Citations
1Safety of efalizumab in adults with chronic moderate to severe plaque psoriasis: a phase IIIb, randomized, controlled trial. (Papp KA, Bressinck R, Fretzin S, Goffe B, Kempers S, Gordon KB, Caro I, Walicke PA, Wang X, Menter A, Efalizumab Study Group) Int J Dermatol 2006 May;45(5):605-14       71 Citations
4A prospective evaluation of opioid weaning in opioid-dependent pediatric critical care patients. (Berens RJ, Meyer MT, Mikhailov TA, Colpaert KD, Czarnecki ML, Ghanayem NS, Hoffman GM, Soetenga DJ, Nelson TJ, Weisman SJ) Anesth Analg 2006 Apr;102(4):1045-50       68 Citations
1Efficacy of etanercept in an integrated multistudy database of patients with psoriasis. (Gordon K, Korman N, Frankel E, Wang H, Jahreis A, Zitnik R, Chang T) J Am Acad Dermatol 2006 Mar;54(3 Suppl 2):S101-11       86 Citations
1Clinical response in psoriasis patients discontinued from and then reinitiated on etanercept therapy. (Gordon KB, Gottlieb AB, Leonardi CL, Elewski BE, Wang A, Jahreis A, Zitnik R) J Dermatolog Treat 2006;17(1):9-17       108 Citations
1Treatment of chronic posterior laryngitis with esomeprazole. (Vaezi MF, Richter JE, Stasney CR, Spiegel JR, Iannuzzi RA, Crawley JA, Hwang C, Sostek MB, Shaker R) Laryngoscope 2006 Feb;116(2):254-60       284 Citations
1Risk factors for post-ERCP pancreatitis: a prospective multicenter study. (Cheng CL, Sherman S, Watkins JL, Barnett J, Freeman M, Geenen J, Ryan M, Parker H, Frakes JT, Fogel EL, Silverman WB, Dua KS, Aliperti G, Yakshe P, Uzer M, Jones W, Goff J, Lazzell-Pannell L, Rashdan A, Temkit M, Lehman GA) Am J Gastroenterol 2006 Jan;101(1):139-47       495 Citations
1Etanercept and clinical outcomes, fatigue, and depression in psoriasis: double-blind placebo-controlled randomised phase III trial. (Tyring S, Gottlieb A, Papp K, Gordon K, Leonardi C, Wang A, Lalla D, Woolley M, Jahreis A, Zitnik R, Cella D, Krishnan R) Lancet 2006 Jan 07;367(9504):29-35       926 Citations
1Effects of mifepristone on proliferation and apoptosis of human endometrium in new users of medroxyprogesterone acetate. (Jain JK, Li A, Yang W, Minoo P, Felix JC) Hum Reprod 2006 Mar;21(3):798-809       17 Citations
1The tumour necrosis factor-alpha inhibitor adalimumab rapidly reverses the decrease in epidermal Langerhans cell density in psoriatic plaques. (Gordon KB, Bonish BK, Patel T, Leonardi CL, Nickoloff BJ) Br J Dermatol 2005 Nov;153(5):945-53       59 Citations
1Safety results of two phase III trials of an intravitreous injection of highly purified ovine hyaluronidase (Vitrase) for the management of vitreous hemorrhage. (Kuppermann BD, Thomas EL, de Smet MD, Grillone LR, Vitrase for Vitreous Hemorrhage Study Groups) Am J Ophthalmol 2005 Oct;140(4):585-97       75 Citations
1A phase II randomized double-masked trial of pegaptanib, an anti-vascular endothelial growth factor aptamer, for diabetic macular edema. (Cunningham ET Jr, Adamis AP, Altaweel M, Aiello LP, Bressler NM, D'Amico DJ, Goldbaum M, Guyer DR, Katz B, Patel M, Schwartz SD, Macugen Diabetic Retinopathy Study Group) Ophthalmology 2005 Oct;112(10):1747-57       545 Citations
1Pooled efficacy results from two multinational randomized controlled clinical trials of a single intravitreous injection of highly purified ovine hyaluronidase (Vitrase) for the management of vitreous hemorrhage. (Kuppermann BD, Thomas EL, de Smet MD, Grillone LR, Vitrase for Vitreous Hemorrhage Study Groups) Am J Ophthalmol 2005 Oct;140(4):573-84       87 Citations
1Effect of an inspiratory impedance threshold device on hemodynamics during conventional manual cardiopulmonary resuscitation. (Pirrallo RG, Aufderheide TP, Provo TA, Lurie KG) Resuscitation 2005 Jul;66(1):13-20       75 Citations
2A vancomycin-heparin lock solution for prevention of nosocomial bloodstream infection in critically ill neonates with peripherally inserted central venous catheters: a prospective, randomized trial. (Garland JS, Alex CP, Henrickson KJ, McAuliffe TL, Maki DG) Pediatrics 2005 Aug;116(2):e198-205       132 Citations
1Infliximab treatment results in significant improvement in the quality of life of patients with severe psoriasis: a double-blind placebo-controlled trial. (Feldman SR, Gordon KB, Bala M, Evans R, Li S, Dooley LT, Guzzo C, Patel K, Menter A, Gottlieb AB) Br J Dermatol 2005 May;152(5):954-60       118 Citations
1Clinical evaluation of an inspiratory impedance threshold device during standard cardiopulmonary resuscitation in patients with out-of-hospital cardiac arrest. (Aufderheide TP, Pirrallo RG, Provo TA, Lurie KG) Crit Care Med 2005 Apr;33(4):734-40       111 Citations
1Extended efalizumab therapy improves chronic plaque psoriasis: results from a randomized phase III trial. (Leonardi CL, Papp KA, Gordon KB, Menter A, Feldman SR, Caro I, Walicke PA, Compton PG, Gottlieb AB, Efalizumab Study Group) J Am Acad Dermatol 2005 Mar;52(3 Pt 1):425-33       222 Citations
1Adjunctive subantimicrobial dose doxycycline in the management of institutionalised geriatric patients with chronic periodontitis. (Mohammad AR, Preshaw PM, Bradshaw MH, Hefti AF, Powala CV, Romanowicz M) Gerodontology 2005 Mar;22(1):37-43       26 Citations
1Comparison of treatment benefit and outcome in women versus men with chronic heart failure (from the Valsartan Heart Failure Trial). (Majahalme SK, Baruch L, Aknay N, Goedel-Meinen L, Hofmann M, Hester A, Prescott MF, Feliciano N, Val-HeFT Study Investigators) Am J Cardiol 2005 Feb 15;95(4):529-32       27 Citations
1The efficacy of alefacept in the treatment of chronic plaque psoriasis. (Gordon KB, Valentine J) J Cutan Med Surg 2004 Dec;8 Suppl 2:3-9       4 Citations
1The dual 5-alpha-reductase inhibitor dutasteride induces atrophic changes and decreases relative cancer volume in human prostate. (Iczkowski KA, Qiu J, Qian J, Somerville MC, Rittmaster RS, Andriole GL, Bostwick DG) Urology 2005 Jan;65(1):76-82       66 Citations
1Efficacy and safety observed during 24 weeks of efalizumab therapy in patients with moderate to severe plaque psoriasis. (Menter A, Gordon K, Carey W, Hamilton T, Glazer S, Caro I, Li N, Gulliver W) Arch Dermatol 2005 Jan;141(1):31-8       213 Citations
1Pegaptanib for neovascular age-related macular degeneration. (Gragoudas ES, Adamis AP, Cunningham ET Jr, Feinsod M, Guyer DR, VEGF Inhibition Study in Ocular Neovascularization Clinical Trial Group) N Engl J Med 2004 Dec 30;351(27):2805-16       2130 Citations
1Subantimicrobial dose doxycycline enhances the efficacy of scaling and root planing in chronic periodontitis: a multicenter trial. (Preshaw PM, Hefti AF, Novak MJ, Michalowicz BS, Pihlstrom BL, Schoor R, Trummel CL, Dean J, Van Dyke TE, Walker CB, Bradshaw MH) J Periodontol 2004 Aug;75(8):1068-76       78 Citations
1Routine intravascular ultrasound scanning guidance of coronary stenting is not associated with improved clinical outcomes. (Orford JL, Denktas AE, Williams BA, Fasseas P, Willerson JT, Berger PB, Holmes DR Jr, PRESTO Investigators) Am Heart J 2004 Sep;148(3):501-6       22 Citations
1Interleukin-1 polymorphisms are associated with the inflammatory response in human muscle to acute resistance exercise. (Dennis RA, Trappe TA, Simpson P, Carroll C, Huang BE, Nagarajan R, Bearden E, Gurley C, Duff GW, Evans WJ, Kornman K, Peterson CA) J Physiol 2004 Nov 01;560(Pt 3):617-26       52 Citations
1Comparison of preoperative carprofen and postoperative butorphanol as postsurgical analgesics in cats undergoing ovariohysterectomy. (Al-Gizawiy MM, P Rudé E) Vet Anaesth Analg 2004 Jul;31(3):164-74       53 Citations
1Controlled-release oxycodone is better tolerated than intravenous tramadol/metamizol for postoperative analgesia after retinal-surgery. (Kaufmann J, Yesiloglu S, Patermann B, Krombach J, Kiencke P, Kampe S) Curr Eye Res 2004 Apr;28(4):271-5       18 Citations
1Blood pressure and risk of secondary cardiovascular events in women: the Women's Antioxidant Cardiovascular Study (WACS). (Mason PJ, Manson JE, Sesso HD, Albert CM, Chown MJ, Cook NR, Greenland P, Ridker PM, Glynn RJ) Circulation 2004 Apr 06;109(13):1623-9       35 Citations
1A randomized trial of early versus standard inhaled nitric oxide therapy in term and near-term newborn infants with hypoxic respiratory failure. (Konduri GG, Solimano A, Sokol GM, Singer J, Ehrenkranz RA, Singhal N, Wright LL, Van Meurs K, Stork E, Kirpalani H, Peliowski A, Neonatal Inhaled Nitric Oxide Study Group) Pediatrics 2004 Mar;113(3 Pt 1):559-64       148 Citations
1Clinical evaluation of the effects of signal integrity and saturation on data availability and accuracy of Masimo SE and Nellcor N-395 oximeters in children. (Robertson FA, Hoffman GM) Anesth Analg 2004 Mar;98(3):617-22, table of contents       18 Citations
1Remittive effects of intramuscular alefacept in psoriasis. (Gordon KB, Langley RG) J Drugs Dermatol 2003 Dec;2(6):624-8       69 Citations
1Surgical site infection and the routine use of perioperative hyperoxia in a general surgical population: a randomized controlled trial. (Pryor KO, Fahey TJ 3rd, Lien CA, Goldstein PA) JAMA 2004 Jan 07;291(1):79-87       292 Citations
1The efficacy of dexmedetomidine versus morphine for postoperative analgesia after major inpatient surgery. (Arain SR, Ruehlow RM, Uhrich TD, Ebert TJ) Anesth Analg 2004 Jan;98(1):153-158       316 Citations
1Efalizumab for patients with moderate to severe plaque psoriasis: a randomized controlled trial. (Gordon KB, Papp KA, Hamilton TK, Walicke PA, Dummer W, Li N, Bresnahan BW, Menter A, Efalizumab Study Group) JAMA 2003 Dec 17;290(23):3073-80       381 Citations
1Treatment of psoriasis with alefacept: correlation of clinical improvement with reductions of memory T-cell counts. (Gordon KB, Vaishnaw AK, O'Gorman J, Haney J, Menter A, Alefacept Clinical Study Group) Arch Dermatol 2003 Dec;139(12):1563-70       90 Citations
1A randomized trial of etanercept as monotherapy for psoriasis. (Gottlieb AB, Matheson RT, Lowe N, Krueger GG, Kang S, Goffe BS, Gaspari AA, Ling M, Weinstein GD, Nayak A, Gordon KB, Zitnik R) Arch Dermatol 2003 Dec;139(12):1627-32; discussion 1632       448 Citations
1Effects of estrogen plus progestin on risk of fracture and bone mineral density: the Women's Health Initiative randomized trial. (Cauley JA, Robbins J, Chen Z, Cummings SR, Jackson RD, LaCroix AZ, LeBoff M, Lewis CE, McGowan J, Neuner J, Pettinger M, Stefanick ML, Wactawski-Wende J, Watts NB, Women's Health Initiative Investigators) JAMA 2003 Oct 01;290(13):1729-38       1044 Citations
2Acetazolamide reduces referred postoperative pain after laparoscopic surgery with carbon dioxide insufflation. (Woehlck HJ, Otterson M, Yun H, Connolly LA, Eastwood D, Colpaert K) Anesthesiology 2003 Oct;99(4):924-8       21 Citations
1Short- and long-term COX-2 inhibition reverses endothelial dysfunction in patients with hypertension. (Widlansky ME, Price DT, Gokce N, Eberhardt RT, Duffy SJ, Holbrook M, Maxwell C, Palmisano J, Keaney JF Jr, Morrow JD, Vita JA) Hypertension 2003 Sep;42(3):310-5       144 Citations
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1Does prophylactic administration of corticosteroid reduce the risk and severity of post-ERCP pancreatitis: a randomized, prospective, multicenter study. (Sherman S, Blaut U, Watkins JL, Barnett J, Freeman M, Geenen J, Ryan M, Parker H, Frakes JT, Fogel EL, Silverman WB, Dua KS, Aliperti G, Yakshe P, Uzer M, Jones W, Goff J, Earle D, Temkit M, Lehman GA) Gastrointest Endosc 2003 Jul;58(1):23-9       67 Citations
1Intrapocket anesthesia for scaling and root planing in pain-sensitive patients. (Magnusson I, Geurs NC, Harris PA, Hefti AF, Mariotti AJ, Mauriello SM, Soler L, Offenbacher S) J Periodontol 2003 May;74(5):597-602       32 Citations
1The efficacy, side effects, and recovery characteristics of dexmedetomidine versus propofol when used for intraoperative sedation. (Arain SR, Ebert TJ) Anesth Analg 2002 Aug;95(2):461-6, table of contents       261 Citations
1Continuous epidural, not intravenous, droperidol inhibits pruritus, nausea, and vomiting during epidural morphine analgesia. (Nakata K, Mammoto T, Kita T, Taniguchi H, Kanbara N, Akamatsu T, Sakai T, Kishi Y) J Clin Anesth 2002 Mar;14(2):121-5       29 Citations
1Micronized progesterone regulation of the endometrial glandular cycling pool. (Moyer DL, Felix JC, Kurman RJ, Cuffie CA) Int J Gynecol Pathol 2001 Oct;20(4):374-9       9 Citations
1Conscious sedation with midazolam or propofol does not alter left ventricular diastolic performance in patients with preexisting diastolic dysfunction: a transmitral and tissue Doppler transthoracic echocardiography study. (Gare M, Parail A, Milosavljevic D, Kersten JR, Warltier DC, Pagel PS) Anesth Analg 2001 Oct;93(4):865-71       26 Citations
1Ingested IFN-alpha: results of a pilot study in relapsing-remitting MS. (Brod SA, Lindsey JW, Vriesendorp FS, Ahn C, Henninger E, Narayana PA, Wolinsky JS) Neurology 2001 Sep 11;57(5):845-52       27 Citations
1Subantimicrobial dose doxycycline as an adjunct to scaling and root planing: post-treatment effects. (Caton JG, Ciancio SG, Blieden TM, Bradshaw M, Crout RJ, Hefti AF, Massaro JM, Polson AM, Thomas J, Walker C) J Clin Periodontol 2001 Aug;28(8):782-9       71 Citations
1The new proton pump inhibitor esomeprazole is effective as a maintenance therapy in GERD patients with healed erosive oesophagitis: a 6-month, randomized, double-blind, placebo-controlled study of efficacy and safety. (Vakil NB, Shaker R, Johnson DA, Kovacs T, Baerg RD, Hwang C, D'Amico D, Hamelin B) Aliment Pharmacol Ther 2001 Jul;15(7):927-35       124 Citations
1Premedication modifies the quality of sedation with propofol during regional anesthesia. (Nakagawa M, Mammoto T, Sakai T, Kishi Y, Mashimo T) Can J Anaesth 2001 Mar;48(3):284-7       6 Citations
2Randomized trial of oral hydrocortisone and its effect on emergency physicians during night duty. (Whitcomb JE, Findling JW, Raff H, Harnsher K) WMJ 2000 Oct;99(7):37-41, 46       6 Citations
1Treatment of children with early pre-B and pre-B acute lymphocytic leukemia with antimetabolite-based intensification regimens: a Pediatric Oncology Group Study. (Harris MB, Shuster JJ, Pullen J, Borowitz MJ, Carroll AJ, Behm FG, Camitta B, Land VJ) Leukemia 2000 Sep;14(9):1570-6       25 Citations
1Norethindrone acetate and estradiol-induced endometrial hyperplasia. (Kurman RJ, Félix JC, Archer DF, Nanavati N, Arce J, Moyer DL) Obstet Gynecol 2000 Sep;96(3):373-9       59 Citations
1Recombinant human relaxin in the treatment of scleroderma. A randomized, double-blind, placebo-controlled trial. (Seibold JR, Korn JH, Simms R, Clements PJ, Moreland LW, Mayes MD, Furst DE, Rothfield N, Steen V, Weisman M, Collier D, Wigley FM, Merkel PA, Csuka ME, Hsu V, Rocco S, Erikson M, Hannigan J, Harkonen WS, Sanders ME) Ann Intern Med 2000 Jun 06;132(11):871-9       234 Citations
1Use of active noise cancellation devices in caregivers in the intensive care unit. (Akhtar S, Weigle CG, Cheng EY, Toohill R, Berens RJ) Crit Care Med 2000 Apr;28(4):1157-60       24 Citations
1Treatment with subantimicrobial dose doxycycline improves the efficacy of scaling and root planing in patients with adult periodontitis. (Caton JG, Ciancio SG, Blieden TM, Bradshaw M, Crout RJ, Hefti AF, Massaro JM, Polson AM, Thomas J, Walker C) J Periodontol 2000 Apr;71(4):521-32       198 Citations
1Randomized trial of candesartan cilexetil in the treatment of patients with congestive heart failure and a history of intolerance to angiotensin-converting enzyme inhibitors. (Granger CB, Ertl G, Kuch J, Maggioni AP, McMurray J, Rouleau JL, Stevenson LW, Swedberg K, Young J, Yusuf S, Califf RM, Bart BA, Held P, Michelson EL, Sellers MA, Ohlin G, Sparapani R, Pfeffer MA) Am Heart J 2000 Apr;139(4):609-17       106 Citations
1Etanercept in children with polyarticular juvenile rheumatoid arthritis. Pediatric Rheumatology Collaborative Study Group. (Lovell DJ, Giannini EH, Reiff A, Cawkwell GD, Silverman ED, Nocton JJ, Stein LD, Gedalia A, Ilowite NT, Wallace CA, Whitmore J, Finck BK) N Engl J Med 2000 Mar 16;342(11):763-9       1097 Citations
1Prevention of central venous catheter-related infections and thrombotic events in immunocompromised children by the use of vancomycin/ciprofloxacin/heparin flush solution: A randomized, multicenter, double-blind trial. (Henrickson KJ, Axtell RA, Hoover SM, Kuhn SM, Pritchett J, Kehl SC, Klein JP) J Clin Oncol 2000 Mar;18(6):1269-78       211 Citations
1Sedative, amnestic, and analgesic properties of small-dose dexmedetomidine infusions. (Hall JE, Uhrich TD, Barney JA, Arain SR, Ebert TJ) Anesth Analg 2000 Mar;90(3):699-705       841 Citations
1Comparison of sibrafiban with aspirin for prevention of cardiovascular events after acute coronary syndromes: a randomised trial. The SYMPHONY Investigators. Sibrafiban versus Aspirin to Yield Maximum Protection from Ischemic Heart Events Post-acute Coronary Syndromes. () Lancet 2000 Jan 29;355(9201):337-45       284 Citations
1A randomized comparison of ketorolac tromethamine and morphine for postoperative analgesia in critically ill children. (Lieh-Lai MW, Kauffman RE, Uy HG, Danjin M, Simpson PM) Crit Care Med 1999 Dec;27(12):2786-91       53 Citations
1Lorazepam to prevent alcohol withdrawal seizures. (Seidl JJ, Layde P) J Fam Pract 1999 Aug;48(8):575-6    
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1Flumazenil in children after esophagogastroduodenoscopy. (Peters JM, Tolia V, Simpson P, Aravind MK, Kauffman RE) Am J Gastroenterol 1999 Jul;94(7):1857-61       23 Citations
1Clinical significance of thrombocytopenia during a non-ST-elevation acute coronary syndrome. The platelet glycoprotein IIb/IIIa in unstable angina: receptor suppression using integrilin therapy (PURSUIT) trial experience. (McClure MW, Berkowitz SD, Sparapani R, Tuttle R, Kleiman NS, Berdan LG, Lincoff AM, Deckers J, Diaz R, Karsch KR, Gretler D, Kitt M, Simoons M, Topol EJ, Califf RM, Harrington RA) Circulation 1999 Jun 08;99(22):2892-900       143 Citations
1A randomized clinical trial of dermal anesthesia by iontophoresis for peripheral intravenous catheter placement in children. (Kim MK, Kini NM, Troshynski TJ, Hennes HM) Ann Emerg Med 1999 Apr;33(4):395-9       59 Citations
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1The effects of preanesthetic oral clonidine on total requirement of propofol for general anesthesia. (Imai Y, Mammoto T, Murakami K, Kita T, Sakai T, Kagawa K, Kirita T, Sugimura M, Kishi Y) J Clin Anesth 1998 Dec;10(8):660-5       28 Citations
1Adjunctive use of a subgingival controlled-release chlorhexidine chip reduces probing depth and improves attachment level compared with scaling and root planing alone. (Jeffcoat MK, Bray KS, Ciancio SG, Dentino AR, Fine DH, Gordon JM, Gunsolley JC, Killoy WJ, Lowenguth RA, Magnusson NI, Offenbacher S, Palcanis KG, Proskin HM, Finkelman RD, Flashner M) J Periodontol 1998 Sep;69(9):989-97       157 Citations
1Inhibition of platelet glycoprotein IIb/IIIa with eptifibatide in patients with acute coronary syndromes. (Platelet Glycoprotein IIb/IIIa in Unstable Angina: Receptor Suppression Using Integrilin Therapy (PURSUIT) Trial Investigators) N Engl J Med 1998 Aug 13;339(7):436-43       1721 Citations
1Oral iloprost treatment in patients with Raynaud's phenomenon secondary to systemic sclerosis: a multicenter, placebo-controlled, double-blind study. (Wigley FM, Korn JH, Csuka ME, Medsger TA Jr, Rothfield NF, Ellman M, Martin R, Collier DH, Weinstein A, Furst DE, Jimenez SA, Mayes MD, Merkel PA, Gruber B, Kaufman L, Varga J, Bell P, Kern J, Marrott P, White B, Simms RW, Phillips AC, Seibold JR) Arthritis Rheum 1998 Apr;41(4):670-7       160 Citations
1A meta-analysis of zinc salts lozenges and the common cold. (Jackson JL, Peterson C, Lesho E) Arch Intern Med 1997 Nov 10;157(20):2373-6       60 Citations
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1Dexamethasone for the prevention of postextubation airway obstruction: a prospective, randomized, double-blind, placebo-controlled trial. (Anene O, Meert KL, Uy H, Simpson P, Sarnaik AP) Crit Care Med 1996 Oct;24(10):1666-9       127 Citations
1Clinical evaluation of an ionic toothbrush in the removal of established plaque and reduction of gingivitis. (Van Swol RL, Van Scotter DE, Pucher JJ, Dentino AR) Quintessence Int 1996 Jun;27(6):389-94       17 Citations
1Efficacy and safety of divided dose administration of mivacurium for a 90-second tracheal intubation. (Ali HH, Lien CA, Witkowski T, Brull SJ, Stout RG, Bartkowski R, Silverman DG, Patel S, Ascher JA, Goudsouzian NG) J Clin Anesth 1996 Jun;8(4):276-81       21 Citations
1A treatment and withdrawal trial of besipirdine in Alzheimer disease. (Huff FJ, Antuono PG, Delagandara JE, McDonald MA, Cutler NR, Cohen SR, Green RC, Zemlan FP, Crismon ML, Alter M, Shipley JE, Reichman WE) Alzheimer Dis Assoc Disord 1996;10(2):93-102       15 Citations
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1A double-blind evaluation of ketorolac tromethamine versus acetaminophen in pediatric tonsillectomy: analgesia and bleeding. (Rusy LM, Houck CS, Sullivan LJ, Ohlms LA, Jones DT, McGill TJ, Berde CB) Anesth Analg 1995 Feb;80(2):226-9       227 Citations
1Albuterol delivered by metered-dose inhaler to treat acute bronchitis. (Hueston WJ) J Fam Pract 1994 Nov;39(5):437-40       75 Citations
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1Treatment of abnormal eye movements that impair vision: strategies based on current concepts of physiology and pharmacology. (Leigh RJ, Averbuch-Heller L, Tomsak RL, Remler BF, Yaniglos SS, Dell'Osso LF) Ann Neurol 1994 Aug;36(2):129-41       63 Citations
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1Efficacy of an influenza hemagglutinin-diphtheria toxoid conjugate vaccine in elderly nursing home subjects during an influenza outbreak. (Gravenstein S, Drinka P, Duthie EH, Miller BA, Brown CS, Hensley M, Circo R, Langer E, Ershler WB) J Am Geriatr Soc 1994 Mar;42(3):245-51       99 Citations
1The effect of chronic alprazolam on sleep and bioamine metabolites in depression. (Zarcone VP Jr, Benson KL, Greene KA, Csernansky JG, Faull KF) J Clin Psychopharmacol 1994 Feb;14(1):36-40       9 Citations
1A phase III trial of recombinant human erythropoietin therapy in nonanemic orthopedic patients subjected to aggressive removal of blood for autologous use: dose, response, toxicity, and efficacy. (Goodnough LT, Price TH, Friedman KD, Johnston M, Ciavarella D, Khan N, Sacher R, Vogler WR, Wissel M, Abels RI) Transfusion 1994 Jan;34(1):66-71       115 Citations
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1Improved baroreflex sensitivity in elderly hypertensives on lisinopril is not explained by blood pressure reduction alone. (Egan BM, Fleissner MJ, Stepniakowski K, Neahring JM, Sagar KB, Ebert TJ) J Hypertens 1993 Oct;11(10):1113-20       30 Citations
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1Augmentation of influenza antibody response in elderly men by thymosin alpha one. A double-blind placebo-controlled clinical study. (Gravenstein S, Duthie EH, Miller BA, Roecker E, Drinka P, Prathipati K, Ershler WB) J Am Geriatr Soc 1989 Jan;37(1):1-8       63 Citations
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