| 1 | Shortened ex vivo manufacturing time of EGFRvIII-specific chimeric antigen receptor (CAR) T cells reduces immune exhaustion and enhances antiglioma therapeutic function. (Caruso HG, Tanaka R, Liang J, Ling X, Sabbagh A, Henry VK, Collier TL, Heimberger AB) J Neurooncol 2019 Dec;145(3):429-439 1 Citation |
| 2 | Methods for imaging mammalian mitochondrial morphology: A prospective on MitoGraph. (Harwig MC, Viana MP, Egner JM, Harwig JJ, Widlansky ME, Rafelski SM, Hill RB) Anal Biochem 2018 07 01;552:81-99 10 Citations |
| 1 | Intravenous Administration of a MTMR2-Encoding AAV Vector Ameliorates the Phenotype of Myotubular Myopathy in Mice. (Danièle N, Moal C, Julien L, Marinello M, Jamet T, Martin S, Vignaud A, Lawlor MW, Buj-Bello A) J Neuropathol Exp Neurol 2018 04 01;77(4):282-295 6 Citations |
| 1 | α1-Adrenergic Receptors Function Within Hetero-Oligomeric Complexes With Atypical Chemokine Receptor 3 and Chemokine (C-X-C motif) Receptor 4 in Vascular Smooth Muscle Cells. (Albee LJ, Eby JM, Tripathi A, LaPorte HM, Gao X, Volkman BF, Gaponenko V, Majetschak M) J Am Heart Assoc 2017 Aug 17;6(8) 11 Citations |
| 1 | miR-382 Contributes to Renal Tubulointerstitial Fibrosis by Downregulating HSPD1. (Fang Y, Xie T, Xue N, Kuang Q, Wei Z, Liang M, Ding X) Oxid Med Cell Longev 2017;2017:4708516 11 Citations |
| 3 | Cardiotonic Steroids Stimulate Macrophage Inflammatory Responses Through a Pathway Involving CD36, TLR4, and Na/K-ATPase. (Chen Y, Huang W, Yang M, Xin G, Cui W, Xie Z, Silverstein RL) Arterioscler Thromb Vasc Biol 2017 08;37(8):1462-1469 10 Citations |
| 1 | Exosome-Derived miR-25-3p and miR-92a-3p Stimulate Liposarcoma Progression. (Casadei L, Calore F, Creighton CJ, Guescini M, Batte K, Iwenofu OH, Zewdu A, Braggio DA, Bill KL, Fadda P, Lovat F, Lopez G, Gasparini P, Chen JL, Kladney RD, Leone G, Lev D, Croce CM, Pollock RE) Cancer Res 2017 07 15;77(14):3846-3856 52 Citations |
| 2 | Clinical and laboratory phenotype variability in type 2M von Willebrand disease. (Doruelo AL, Haberichter SL, Christopherson PA, Boggio LN, Gupta S, Lentz SR, Shapiro AD, Montgomery RR, Flood VH) J Thromb Haemost 2017 08;15(8):1559-1566 4 Citations |
| 1 | The application of CRISPR technology to high content screening in primary neurons. (Callif BL, Maunze B, Krueger NL, Simpson MT, Blackmore MG) Mol Cell Neurosci 2017 04;80:170-179 7 Citations |
| 2 | Sucrose Nonfermenting-Related Kinase Enzyme-Mediated Rho-Associated Kinase Signaling is Responsible for Cardiac Function. (Cossette SM, Bhute VJ, Bao X, Harmann LM, Horswill MA, Sinha I, Gastonguay A, Pooya S, Bordas M, Kumar SN, Mirza SP, Palecek SP, Strande JL, Ramchandran R) Circ Cardiovasc Genet 2016 Dec;9(6):474-486 7 Citations |
| 1 | Improving vascular maturation using noncoding RNAs increases antitumor effect of chemotherapy. (Mangala LS, Wang H, Jiang D, Wu SY, Somasunderam A, Volk DE, Lokesh GLR, Li X, Pradeep S, Yang X, Haemmerle M, Rodriguez-Aguayo C, Nagaraja AS, Rupaimoole R, Bayraktar E, Bayraktar R, Li L, Tanaka T, Hu W, Ivan C, Gharpure KM, McGuire MH, Thiviyanathan V, Zhang X, Maiti SN, Bulayeva N, Choi HJ, Dorniak PL, Cooper LJ, Rosenblatt KP, Lopez-Berestein G, Gorenstein DG, Sood AK) JCI Insight 2016 Oct 20;1(17):e87754 8 Citations |
| 1 | Monosialoganglioside-Containing Nanoliposomes Restore Endothelial Function Impaired by AL Amyloidosis Light Chain Proteins. (Franco DA, Truran S, Weissig V, Guzman-Villanueva D, Karamanova N, Senapati S, Burciu C, Ramirez-Alvarado M, Blancas-Mejia LM, Lindsay S, Hari P, Migrino RQ) J Am Heart Assoc 2016 06 13;5(6) 3 Citations |
| 2 | Antiendothelial αvβ3 Antibodies Are a Major Cause of Intracranial Bleeding in Fetal/Neonatal Alloimmune Thrombocytopenia. (Santoso S, Wihadmadyatami H, Bakchoul T, Werth S, Al-Fakhri N, Bein G, Kiefel V, Zhu J, Newman PJ, Bayat B, Sachs UJ) Arterioscler Thromb Vasc Biol 2016 08;36(8):1517-24 37 Citations |
| 1 | miR-21 contributes to renal protection by targeting prolyl hydroxylase domain protein 2 in delayed ischaemic preconditioning. (Jiao X, Xu X, Fang Y, Zhang H, Liang M, Teng J, Ding X) Nephrology (Carlton) 2017 May;22(5):366-373 9 Citations |
| 1 | LPA/PKD-1-FoxO1 Signaling Axis Mediates Endothelial Cell CD36 Transcriptional Repression and Proangiogenic and Proarteriogenic Reprogramming. (Ren B, Best B, Ramakrishnan DP, Walcott BP, Storz P, Silverstein RL) Arterioscler Thromb Vasc Biol 2016 06;36(6):1197-208 18 Citations |
| 1 | Estrogen Receptor α Is Required for Maintaining Baseline Renin Expression. (Lu KT, Keen HL, Weatherford ET, Sequeira-Lopez ML, Gomez RA, Sigmund CD) Hypertension 2016 May;67(5):992-9 7 Citations |
| 2 | Ndufc2 Gene Inhibition Is Associated With Mitochondrial Dysfunction and Increased Stroke Susceptibility in an Animal Model of Complex Human Disease. (Rubattu S, Di Castro S, Schulz H, Geurts AM, Cotugno M, Bianchi F, Maatz H, Hummel O, Falak S, Stanzione R, Marchitti S, Scarpino S, Giusti B, Kura A, Gensini GF, Peyvandi F, Mannucci PM, Rasura M, Sciarretta S, Dwinell MR, Hubner N, Volpe M) J Am Heart Assoc 2016 Feb 17;5(2) |
| 1 | Variants in TRIM22 That Affect NOD2 Signaling Are Associated With Very-Early-Onset Inflammatory Bowel Disease. (Li Q, Lee CH, Peters LA, Mastropaolo LA, Thoeni C, Elkadri A, Schwerd T, Zhu J, Zhang B, Zhao Y, Hao K, Dinarzo A, Hoffman G, Kidd BA, Murchie R, Al Adham Z, Guo C, Kotlarz D, Cutz E, Walters TD, Shouval DS, Curran M, Dobrin R, Brodmerkel C, Snapper SB, Klein C, Brumell JH, Hu M, Nanan R, Snanter-Nanan B, Wong M, Le Deist F, Haddad E, Roifman CM, Deslandres C, Griffiths AM, Gaskin KJ, Uhlig HH, Schadt EE, Muise AM) Gastroenterology 2016 05;150(5):1196-1207 44 Citations |
| 2 | Extracellular Vesicles Activate a CD36-Dependent Signaling Pathway to Inhibit Microvascular Endothelial Cell Migration and Tube Formation. (Ramakrishnan DP, Hajj-Ali RA, Chen Y, Silverstein RL) Arterioscler Thromb Vasc Biol 2016 Mar;36(3):534-44 24 Citations |
| 2 | Structural basis for PECAM-1 homophilic binding. (Paddock C, Zhou D, Lertkiatmongkol P, Newman PJ, Zhu J) Blood 2016 Feb 25;127(8):1052-61 25 Citations |
| 1 | Valve Endothelial Cell-Derived Tgfβ1 Signaling Promotes Nuclear Localization of Sox9 in Interstitial Cells Associated With Attenuated Calcification. (Huk DJ, Austin BF, Horne TE, Hinton RB, Ray WC, Heistad DD, Lincoln J) Arterioscler Thromb Vasc Biol 2016 Feb;36(2):328-38 30 Citations |
| 1 | Neuronostatin acts via GPR107 to increase cAMP-independent PKA phosphorylation and proglucagon mRNA accumulation in pancreatic α-cells. (Elrick MM, Samson WK, Corbett JA, Salvatori AS, Stein LM, Kolar GR, Naatz A, Yosten GL) Am J Physiol Regul Integr Comp Physiol 2016 Jan 15;310(2):R143-55 17 Citations |
| 1 | The tumor suppressor HHEX inhibits axon growth when prematurely expressed in developing central nervous system neurons. (Simpson MT, Venkatesh I, Callif BL, Thiel LK, Coley DM, Winsor KN, Wang Z, Kramer AA, Lerch JK, Blackmore MG) Mol Cell Neurosci 2015 Sep;68:272-83 12 Citations |
| 2 | Acceleration of Lung Regeneration by Platelet-Rich Plasma Extract through the Low-Density Lipoprotein Receptor-Related Protein 5-Tie2 Pathway. (Mammoto T, Chen Z, Jiang A, Jiang E, Ingber DE, Mammoto A) Am J Respir Cell Mol Biol 2016 Jan;54(1):103-13 10 Citations |
| 1 | NPM-ALK mediates phosphorylation of MSH2 at tyrosine 238, creating a functional deficiency in MSH2 and the loss of mismatch repair. (Bone KM, Wang P, Wu F, Wu C, Li L, Bacani JT, Andrew SE, Lai R) Blood Cancer J 2015 May 15;5:e311 6 Citations |
| 2 | MicroRNA-135b Regulates Leucine Zipper Tumor Suppressor 1 in Cutaneous Squamous Cell Carcinoma. (Olasz EB, Seline LN, Schock AM, Duncan NE, Lopez A, Lazar J, Flister MJ, Lu Y, Liu P, Sokumbi O, Harwood CA, Proby CM, Neuburg M, Lazarova Z) PLoS One 2015;10(5):e0125412 17 Citations |
| 2 | Functional Characterization of Nupr1L, A Novel p53-Regulated Isoform of the High-Mobility Group (HMG)-Related Protumoral Protein Nupr1. (Lopez MB, Garcia MN, Grasso D, Bintz J, Molejon MI, Velez G, Lomberk G, Neira JL, Urrutia R, Iovanna J) J Cell Physiol 2015 Dec;230(12):2936-50 4 Citations |
| 1 | XPO1/CRM1 Inhibition Causes Antitumor Effects by Mitochondrial Accumulation of eIF5A. (Miyake T, Pradeep S, Wu SY, Rupaimoole R, Zand B, Wen Y, Gharpure KM, Nagaraja AS, Hu W, Cho MS, Dalton HJ, Previs RA, Taylor ML, Hisamatsu T, Kang Y, Liu T, Shacham S, McCauley D, Hawke DH, Wiktorowicz JE, Coleman RL, Sood AK) Clin Cancer Res 2015 Jul 15;21(14):3286-97 12 Citations |
| 1 | Rac1/Pak1/p38/MMP-2 Axis Regulates Angiogenesis in Ovarian Cancer. (Gonzalez-Villasana V, Fuentes-Mattei E, Ivan C, Dalton HJ, Rodriguez-Aguayo C, Fernandez-de Thomas RJ, Aslan B, Del C Monroig P, Velazquez-Torres G, Previs RA, Pradeep S, Kahraman N, Wang H, Kanlikilicer P, Ozpolat B, Calin G, Sood AK, Lopez-Berestein G) Clin Cancer Res 2015 May 01;21(9):2127-37 42 Citations |
| 1 | Stable and efficient transfection of siRNA for mutated KRAS silencing using novel hybrid nanoparticles. (Lakshmikuttyamma A, Sun Y, Lu B, Undieh AS, Shoyele SA) Mol Pharm 2014 Dec 01;11(12):4415-24 13 Citations |
| 1 | Epidermal growth factor-induced proliferation of collecting duct cells from Oak Ridge polycystic kidney mice involves activation of Na+/H+ exchanger. (Coaxum SD, Blanton MG, Joyner A, Akter T, Bell PD, Luttrell LM, Raymond JR Sr, Lee MH, Blichmann PA, Garnovskaya MN, Saigusa T) Am J Physiol Cell Physiol 2014 Sep 15;307(6):C554-60 7 Citations |
| 2 | Hematogenous metastasis of ovarian cancer: rethinking mode of spread. (Pradeep S, Kim SW, Wu SY, Nishimura M, Chaluvally-Raghavan P, Miyake T, Pecot CV, Kim SJ, Choi HJ, Bischoff FZ, Mayer JA, Huang L, Nick AM, Hall CS, Rodriguez-Aguayo C, Zand B, Dalton HJ, Arumugam T, Lee HJ, Han HD, Cho MS, Rupaimoole R, Mangala LS, Sehgal V, Oh SC, Liu J, Lee JS, Coleman RL, Ram P, Lopez-Berestein G, Fidler IJ, Sood AK) Cancer Cell 2014 Jul 14;26(1):77-91 147 Citations |
| 1 | Post-translational regulation of COX2 activity by FYN in prostate cancer cells. (Alexanian A, Miller B, Chesnik M, Mirza S, Sorokin A) Oncotarget 2014 Jun 30;5(12):4232-43 10 Citations |
| 4 | Identification of a ternary protein-complex as a therapeutic target for K-Ras-dependent colon cancer. (Qi X, Xie C, Hou S, Li G, Yin N, Dong L, Lepp A, Chesnik MA, Mirza SP, Szabo A, Tsai S, Basir Z, Wu S, Chen G) Oncotarget 2014 Jun 30;5(12):4269-82 11 Citations |
| 2 | Differential coupling of KLF10 to Sin3-HDAC and PCAF regulates the inducibility of the FOXP3 gene. (Xiong Y, Svingen PA, Sarmento OO, Smyrk TC, Dave M, Khanna S, Lomberk GA, Urrutia RA, Faubion WA Jr) Am J Physiol Regul Integr Comp Physiol 2014 Sep 15;307(6):R608-20 17 Citations |
| 1 | Variants in nicotinamide adenine dinucleotide phosphate oxidase complex components determine susceptibility to very early onset inflammatory bowel disease. (Dhillon SS, Fattouh R, Elkadri A, Xu W, Murchie R, Walters T, Guo C, Mack D, Huynh HQ, Baksh S, Silverberg MS, Griffiths AM, Snapper SB, Brumell JH, Muise AM) Gastroenterology 2014 Sep;147(3):680-689.e2 73 Citations |
| 4 | Rap1b in smooth muscle and endothelium is required for maintenance of vascular tone and normal blood pressure. (Lakshmikanthan S, Zieba BJ, Ge ZD, Momotani K, Zheng X, Lund H, Artamonov MV, Maas JE, Szabo A, Zhang DX, Auchampach JA, Mattson DL, Somlyo AV, Chrzanowska-Wodnicka M) Arterioscler Thromb Vasc Biol 2014 Jul;34(7):1486-94 27 Citations |
| 1 | Possible role of arginase-1 in concomitant tumor immunity. (Korrer MJ, Zhang Y, Routes JM) PLoS One 2014;9(3):e91370 9 Citations |
| 1 | Autocrine effects of tumor-derived complement. (Cho MS, Vasquez HG, Rupaimoole R, Pradeep S, Wu S, Zand B, Han HD, Rodriguez-Aguayo C, Bottsford-Miller J, Huang J, Miyake T, Choi HJ, Dalton HJ, Ivan C, Baggerly K, Lopez-Berestein G, Sood AK, Afshar-Kharghan V) Cell Rep 2014 Mar 27;6(6):1085-1095 84 Citations |
| 3 | CXCL12 chemokine expression suppresses human pancreatic cancer growth and metastasis. (Roy I, Zimmerman NP, Mackinnon AC, Tsai S, Evans DB, Dwinell MB) PLoS One 2014;9(3):e90400 54 Citations |
| 1 | HO-3867, a safe STAT3 inhibitor, is selectively cytotoxic to ovarian cancer. (Rath KS, Naidu SK, Lata P, Bid HK, Rivera BK, McCann GA, Tierney BJ, Elnaggar AC, Bravo V, Leone G, Houghton P, Hideg K, Kuppusamy P, Cohn DE, Selvendiran K) Cancer Res 2014 Apr 15;74(8):2316-27 47 Citations |
| 3 | Nogo-B receptor modulates angiogenesis response of pulmonary artery endothelial cells through eNOS coupling. (Teng RJ, Rana U, Afolayan AJ, Zhao B, Miao QR, Konduri GG) Am J Respir Cell Mol Biol 2014 Aug;51(2):169-77 12 Citations |
| 1 | Mechanotransduction of fluid stresses governs 3D cell migration. (Polacheck WJ, German AE, Mammoto A, Ingber DE, Kamm RD) Proc Natl Acad Sci U S A 2014 Feb 18;111(7):2447-52 122 Citations |
| 1 | Dickkopf-1, the Wnt antagonist, is induced by acidic pH and mediates epithelial cellular senescence in human reflux esophagitis. (Lyros O, Rafiee P, Nie L, Medda R, Jovanovic N, Schmidt J, Mackinnon A, Venu N, Shaker R) Am J Physiol Gastrointest Liver Physiol 2014 Apr 01;306(7):G557-74 12 Citations |
| 1 | Mutations in tetratricopeptide repeat domain 7A result in a severe form of very early onset inflammatory bowel disease. (Avitzur Y, Guo C, Mastropaolo LA, Bahrami E, Chen H, Zhao Z, Elkadri A, Dhillon S, Murchie R, Fattouh R, Huynh H, Walker JL, Wales PW, Cutz E, Kakuta Y, Dudley J, Kammermeier J, Powrie F, Shah N, Walz C, Nathrath M, Kotlarz D, Puchaka J, Krieger JR, Racek T, Kirchner T, Walters TD, Brumell JH, Griffiths AM, Rezaei N, Rashtian P, Najafi M, Monajemzadeh M, Pelsue S, McGovern DP, Uhlig HH, Schadt E, Klein C, Snapper SB, Muise AM) Gastroenterology 2014 Apr;146(4):1028-39 105 Citations |
| 1 | Acetylation of the cell-fate factor dachshund determines p53 binding and signaling modules in breast cancer. (Chen K, Wu K, Gormley M, Ertel A, Wang J, Zhang W, Zhou J, Disante G, Li Z, Rui H, Quong AA, McMahon SB, Deng H, Lisanti MP, Wang C, Pestell RG) Oncotarget 2013 Jun;4(6):923-35 22 Citations |
| 1 | Nicotine potentiates proatherogenic effects of oxLDL by stimulating and upregulating macrophage CD36 signaling. (Zhou MS, Chadipiralla K, Mendez AJ, Jaimes EA, Silverstein RL, Webster K, Raij L) Am J Physiol Heart Circ Physiol 2013 Aug 15;305(4):H563-74 34 Citations |
| 1 | Statins exert the pleiotropic effects through small GTP-binding protein dissociation stimulator upregulation with a resultant Rac1 degradation. (Tanaka S, Fukumoto Y, Nochioka K, Minami T, Kudo S, Shiba N, Takai Y, Williams CL, Liao JK, Shimokawa H) Arterioscler Thromb Vasc Biol 2013 Jul;33(7):1591-600 49 Citations |
| 1 | Redifferentiation and induction of tumor suppressors miR-122 and miR-375 by the PAX8/PPARγ fusion protein inhibits anaplastic thyroid cancer: a novel therapeutic strategy. (Reddi HV, Driscoll CB, Madde P, Milosevic D, Hurley RM, McDonough SJ, Hallanger-Johnson J, McIver B, Eberhardt NL) Cancer Gene Ther 2013 May;20(5):267-75 16 Citations |
| 1 | Dachshund binds p53 to block the growth of lung adenocarcinoma cells. (Chen K, Wu K, Cai S, Zhang W, Zhou J, Wang J, Ertel A, Li Z, Rui H, Quong A, Lisanti MP, Tozeren A, Tanes C, Addya S, Gormley M, Wang C, McMahon SB, Pestell RG) Cancer Res 2013 Jun 01;73(11):3262-74 45 Citations |
| 1 | Adenosine A1 receptors heterodimerize with β1- and β2-adrenergic receptors creating novel receptor complexes with altered G protein coupling and signaling. (Chandrasekera PC, Wan TC, Gizewski ET, Auchampach JA, Lasley RD) Cell Signal 2013 Apr;25(4):736-42 27 Citations |
| 1 | Increased dietary intake of vitamin A promotes aortic valve calcification in vivo. (Huk DJ, Hammond HL, Kegechika H, Lincoln J) Arterioscler Thromb Vasc Biol 2013 Feb;33(2):285-93 19 Citations |
| 1 | Neutrophil proteinase 3 acts on protease-activated receptor-2 to enhance vascular endothelial cell barrier function. (Kuckleburg CJ, Newman PJ) Arterioscler Thromb Vasc Biol 2013 Feb;33(2):275-84 18 Citations |
| 1 | Glycosylation-independent lysosomal targeting of acid α-glucosidase enhances muscle glycogen clearance in pompe mice. (Maga JA, Zhou J, Kambampati R, Peng S, Wang X, Bohnsack RN, Thomm A, Golata S, Tom P, Dahms NM, Byrne BJ, LeBowitz JH) J Biol Chem 2013 Jan 18;288(3):1428-38 60 Citations |
| 2 | Cullin-3 regulates vascular smooth muscle function and arterial blood pressure via PPARγ and RhoA/Rho-kinase. (Pelham CJ, Ketsawatsomkron P, Groh S, Grobe JL, de Lange WJ, Ibeawuchi SR, Keen HL, Weatherford ET, Faraci FM, Sigmund CD) Cell Metab 2012 Oct 03;16(4):462-72 60 Citations |
| 1 | Comparison of cell expression formats for the characterization of GABA(A) channels using a microfluidic patch clamp system. (Chen Q, Yim PD, Yuan N, Johnson J, Cook JM, Smith S, Ionescu-Zanetti C, Wang ZJ, Arnold LA, Emala CW) Assay Drug Dev Technol 2012 Aug;10(4):325-35 6 Citations |
| 1 | von Willebrand factor (VWF) propeptide binding to VWF D'D3 domain attenuates platelet activation and adhesion. (Madabhushi SR, Shang C, Dayananda KM, Rittenhouse-Olson K, Murphy M, Ryan TE, Montgomery RR, Neelamegham S) Blood 2012 May 17;119(20):4769-78 19 Citations |
| 2 | Intersection of mechanisms of type 2A VWD through defects in VWF multimerization, secretion, ADAMTS-13 susceptibility, and regulated storage. (Jacobi PM, Gill JC, Flood VH, Jakab DA, Friedman KD, Haberichter SL) Blood 2012 May 10;119(19):4543-53 33 Citations |
| 1 | Bystander killing of malignant cells via the delivery of engineered thymidine-active deoxycytidine kinase for suicide gene therapy of cancer. (Neschadim A, Wang JC, Lavie A, Medin JA) Cancer Gene Ther 2012 May;19(5):320-7 18 Citations |
| 1 | [Mechanism of epithelial sodium channel (ENaC) regulation by cortactin: involvement of dynamin]. (Ilatovskaia DV, Pavlov TS, Neguliaev IuA, Starushchenko AV) Tsitologiia 2011;53(11):903-10 3 Citations |
| 1 | CD36 ectodomain phosphorylation blocks thrombospondin-1 binding: structure-function relationships and regulation by protein kinase C. (Chu LY, Silverstein RL) Arterioscler Thromb Vasc Biol 2012 Mar;32(3):760-7 18 Citations |
| 2 | A newly identified complex of spinophilin and the tyrosine phosphatase, SHP-1, modulates platelet activation by regulating G protein-dependent signaling. (Ma P, Cierniewska A, Signarvic R, Cieslak M, Kong H, Sinnamon AJ, Neubig RR, Newman DK, Stalker TJ, Brass LF) Blood 2012 Feb 23;119(8):1935-45 36 Citations |
| 1 | A point mutation in the EGF-4 domain of β(3) integrin is responsible for the formation of the Sec(a) platelet alloantigen and affects receptor function. (Sachs UJ, Bakchoul T, Eva O, Giptner A, Bein G, Aster RH, Gitter M, Peterson J, Santoso S) Thromb Haemost 2012 Jan;107(1):80-7 10 Citations |
| 1 | AAV-mediated gene transfer of human X-linked inhibitor of apoptosis protects against oxidative cell death in human RPE cells. (Shan H, Ji D, Barnard AR, Lipinski DM, You Q, Lee EJ, Kamalden TA, Sun X, MacLaren RE) Invest Ophthalmol Vis Sci 2011 Dec 20;52(13):9591-7 15 Citations |
| 1 | PITX2 is involved in stress response in cultured human trabecular meshwork cells through regulation of SLC13A3. (Strungaru MH, Footz T, Liu Y, Berry FB, Belleau P, Semina EV, Raymond V, Walter MA) Invest Ophthalmol Vis Sci 2011 Sep 29;52(10):7625-33 19 Citations |
| 1 | Defining the nature of human pluripotent stem cell progeny. (Patterson M, Chan DN, Ha I, Case D, Cui Y, Van Handel B, Mikkola HK, Lowry WE) Cell Res 2012 Jan;22(1):178-93 82 Citations |
| 1 | Constitutive androstane receptor activation decreases plasma apolipoprotein B-containing lipoproteins and atherosclerosis in low-density lipoprotein receptor-deficient mice. (Sberna AL, Assem M, Xiao R, Ayers S, Gautier T, Guiu B, Deckert V, Chevriaux A, Grober J, Le Guern N, Pais de Barros JP, Moore DD, Lagrost L, Masson D) Arterioscler Thromb Vasc Biol 2011 Oct;31(10):2232-9 21 Citations |
| 1 | PKCα mediates acetylcholine-induced activation of TRPV4-dependent calcium influx in endothelial cells. (Adapala RK, Talasila PK, Bratz IN, Zhang DX, Suzuki M, Meszaros JG, Thodeti CK) Am J Physiol Heart Circ Physiol 2011 Sep;301(3):H757-65 56 Citations |
| 1 | Effects of cytochrome P-450 metabolites of arachidonic acid on the epithelial sodium channel (ENaC). (Pavlov TS, Ilatovskaya DV, Levchenko V, Mattson DL, Roman RJ, Staruschenko A) Am J Physiol Renal Physiol 2011 Sep;301(3):F672-81 42 Citations |
| 1 | Dual antigen target-based immunotherapy for prostate cancer eliminates the growth of established tumors in mice. (Karan D, Dubey S, Van Veldhuizen P, Holzbeierlein JM, Tawfik O, Thrasher JB) Immunotherapy 2011 Jun;3(6):735-46 16 Citations |
| 2 | Platelet gene therapy improves hemostatic function for integrin alphaIIbbeta3-deficient dogs. (Fang J, Jensen ES, Boudreaux MK, Du LM, Hawkins TB, Koukouritaki SB, Cornetta K, Wilcox DA) Proc Natl Acad Sci U S A 2011 Jun 07;108(23):9583-8 39 Citations |
| 1 | Ubiquitination of GPCRs. (Caballero A, Marchese A) Methods Mol Biol 2011;746:251-9 4 Citations |
| 1 | The protective effect of overexpression of extracellular superoxide dismutase on nitric oxide bioavailability in the lung after exposure to hyperoxia stress. (Ahmed MN, Codipilly C, Hogg N, Auten RL) Exp Lung Res 2011 Feb;37(1):10-7 19 Citations |
| 2 | Pancreatic stellate cell models for transcriptional studies of desmoplasia-associated genes. (Mathison A, Liebl A, Bharucha J, Mukhopadhyay D, Lomberk G, Shah V, Urrutia R) Pancreatology 2010;10(4):505-16 |
| 1 | Plk2 attachment to NSF induces homeostatic removal of GluA2 during chronic overexcitation. (Evers DM, Matta JA, Hoe HS, Zarkowsky D, Lee SH, Isaac JT, Pak DT) Nat Neurosci 2010 Oct;13(10):1199-207 46 Citations |
| 2 | Generation of human induced pluripotent stem cells by simple transient transfection of plasmid DNA encoding reprogramming factors. (Si-Tayeb K, Noto FK, Sepac A, Sedlic F, Bosnjak ZJ, Lough JW, Duncan SA) BMC Dev Biol 2010 Aug 03;10:81 147 Citations |
| 1 | Combinatorial chemoprevention reveals a novel smoothened-independent role of GLI1 in esophageal carcinogenesis. (Rizvi S, Demars CJ, Comba A, Gainullin VG, Rizvi Z, Almada LL, Wang K, Lomberk G, Fernández-Zapico ME, Buttar NS) Cancer Res 2010 Sep 01;70(17):6787-96 36 Citations |
| 1 | Leukemia inhibitory factor can mediate Ras/Raf/MEK/ERK-induced growth inhibitory signaling in medullary thyroid cancer cells. (Arthan D, Hong SK, Park JI) Cancer Lett 2010 Nov 01;297(1):31-41 34 Citations |
| 1 | Polymorphic variation in cytochrome oxidase subunit genes. (Lu J, Wang K, Rodova M, Esteves R, Berry D, E L, Crafter A, Barrett M, Cardoso SM, Onyango I, Parker WD, Fontes J, Burns JM, Swerdlow RH) J Alzheimers Dis 2010;21(1):141-54 21 Citations |
| 1 | Pigment epithelium-derived factor stimulates tumor macrophage recruitment and is downregulated by the prostate tumor microenvironment. (Halin S, Rudolfsson SH, Doll JA, Crawford SE, Wikström P, Bergh A) Neoplasia 2010 Apr;12(4):336-45 30 Citations |
| 1 | Endothelial cell-specific chemotaxis receptor (ecscr) promotes angioblast migration during vasculogenesis and enhances VEGF receptor sensitivity. (Verma A, Bhattacharya R, Remadevi I, Li K, Pramanik K, Samant GV, Horswill M, Chun CZ, Zhao B, Wang E, Miao RQ, Mukhopadhyay D, Ramchandran R, Wilkinson GA) Blood 2010 Jun 03;115(22):4614-22 23 Citations |
| 1 | Reduced sox9 function promotes heart valve calcification phenotypes in vivo. (Peacock JD, Levay AK, Gillaspie DB, Tao G, Lincoln J) Circ Res 2010 Mar 05;106(4):712-9 85 Citations |
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| 1 | Molecular determinants dictating cell surface expression of the human sodium-dependent vitamin C transporter-2 in human liver cells. (Subramanian VS, Marchant JS, Said HM) Am J Physiol Gastrointest Liver Physiol 2010 Feb;298(2):G267-74 9 Citations |
| 1 | Synthetic cannabinoid receptor agonists inhibit tumor growth and metastasis of breast cancer. (Qamri Z, Preet A, Nasser MW, Bass CE, Leone G, Barsky SH, Ganju RK) Mol Cancer Ther 2009 Nov;8(11):3117-29 134 Citations |
| 1 | Identification and characterization of a novel ABCA3 mutation. (Park SK, Amos L, Rao A, Quasney MW, Matsumura Y, Inagaki N, Dahmer MK) Physiol Genomics 2010 Jan 08;40(2):94-9 14 Citations |
| 1 | Facilitative glucose transporter 9 expression affects glucose sensing in pancreatic beta-cells. (Evans SA, Doblado M, Chi MM, Corbett JA, Moley KH) Endocrinology 2009 Dec;150(12):5302-10 37 Citations |
| 1 | Noncatalytic function of ERK1/2 can promote Raf/MEK/ERK-mediated growth arrest signaling. (Hong SK, Yoon S, Moelling C, Arthan D, Park JI) J Biol Chem 2009 Nov 27;284(48):33006-18 55 Citations |
| 3 | Identification and functional characterization of phosphorylation sites on GTP cyclohydrolase I. (Du J, Wei N, Xu H, Ge Y, Vásquez-Vivar J, Guan T, Oldham KT, Pritchard KA Jr, Shi Y) Arterioscler Thromb Vasc Biol 2009 Dec;29(12):2161-8 8 Citations |
| 1 | The cell fate determination factor DACH1 is expressed in estrogen receptor-alpha-positive breast cancer and represses estrogen receptor-alpha signaling. (Popov VM, Zhou J, Shirley LA, Quong J, Yeow WS, Wright JA, Wu K, Rui H, Vadlamudi RK, Jiang J, Kumar R, Wang C, Pestell RG) Cancer Res 2009 Jul 15;69(14):5752-60 44 Citations |
| 1 | Ubiquitination regulates proteolytic processing of G protein-coupled receptors after their sorting to lysosomes. (Hislop JN, Henry AG, Marchese A, von Zastrow M) J Biol Chem 2009 Jul 17;284(29):19361-70 64 Citations |
| 1 | Epidermal growth factor activates Na(+/)H(+) exchanger in podocytes through a mechanism that involves Janus kinase and calmodulin. (Coaxum SD, Garnovskaya MN, Gooz M, Baldys A, Raymond JR) Biochim Biophys Acta 2009 Jul;1793(7):1174-81 36 Citations |
| 1 | Role of nuclear-encoded subunit Vb in the assembly and stability of cytochrome c oxidase complex: implications in mitochondrial dysfunction and ROS production. (Galati D, Srinivasan S, Raza H, Prabu SK, Hardy M, Chandran K, Lopez M, Kalyanaraman B, Avadhani NG) Biochem J 2009 May 27;420(3):439-49 61 Citations |
| 1 | The major human pregnane X receptor (PXR) splice variant, PXR.2, exhibits significantly diminished ligand-activated transcriptional regulation. (Lin YS, Yasuda K, Assem M, Cline C, Barber J, Li CW, Kholodovych V, Ai N, Chen JD, Welsh WJ, Ekins S, Schuetz EG) Drug Metab Dispos 2009 Jun;37(6):1295-304 27 Citations |
| 1 | Membrane targeting and intracellular trafficking of the human sodium-dependent multivitamin transporter in polarized epithelial cells. (Subramanian VS, Marchant JS, Boulware MJ, Ma TY, Said HM) Am J Physiol Cell Physiol 2009 Apr;296(4):C663-71 24 Citations |
| 1 | Vasculostatin inhibits intracranial glioma growth and negatively regulates in vivo angiogenesis through a CD36-dependent mechanism. (Kaur B, Cork SM, Sandberg EM, Devi NS, Zhang Z, Klenotic PA, Febbraio M, Shim H, Mao H, Tucker-Burden C, Silverstein RL, Brat DJ, Olson JJ, Van Meir EG) Cancer Res 2009 Feb 01;69(3):1212-20 75 Citations |
| 1 | Proteasome-mediated degradation and functions of hematopoietic progenitor kinase 1 in pancreatic cancer. (Wang H, Song X, Logsdon C, Zhou G, Evans DB, Abbruzzese JL, Hamilton SR, Tan TH, Wang H) Cancer Res 2009 Feb 01;69(3):1063-70 22 Citations |
| 1 | Activin C antagonizes activin A in vitro and overexpression leads to pathologies in vivo. (Gold E, Jetly N, O'Bryan MK, Meachem S, Srinivasan D, Behuria S, Sanchez-Partida LG, Woodruff T, Hedwards S, Wang H, McDougall H, Casey V, Niranjan B, Patella S, Risbridger G) Am J Pathol 2009 Jan;174(1):184-95 48 Citations |
| 2 | SmgGDS is up-regulated in prostate carcinoma and promotes tumour phenotypes in prostate cancer cells. (Zhi H, Yang XJ, Kuhnmuench J, Berg T, Thill R, Yang H, See WA, Becker CG, Williams CL, Li R) J Pathol 2009 Feb;217(3):389-97 19 Citations |
| 1 | Regulation of ENaC expression at the cell surface by Rab11. (Karpushev AV, Levchenko V, Pavlov TS, Lam V, Vinnakota KC, Vandewalle A, Wakatsuki T, Staruschenko A) Biochem Biophys Res Commun 2008 Dec 12;377(2):521-525 36 Citations |
| 1 | Molecular characterization of a novel cell surface ADP-ribosyl cyclase from the sea urchin. (Churamani D, Boulware MJ, Ramakrishnan L, Geach TJ, Martin AC, Vacquier VD, Marchant JS, Dale L, Patel S) Cell Signal 2008 Dec;20(12):2347-55 12 Citations |
| 1 | Upstream stimulatory factor is required for human angiotensinogen expression and differential regulation by the A-20C polymorphism. (Dickson ME, Tian X, Liu X, Davis DR, Sigmund CD) Circ Res 2008 Oct 24;103(9):940-7 16 Citations |
| 1 | Polymeric gene delivery of ischemia-inducible VEGF significantly attenuates infarct size and apoptosis following myocardial infarct. (Yockman JW, Choi D, Whitten MG, Chang CW, Kastenmeier A, Erickson H, Albanil A, Lee M, Kim SW, Bull DA) Gene Ther 2009 Jan;16(1):127-35 50 Citations |
| 1 | IL-10 secretion increases signal persistence of HEMA-MMA-microencapsulated luciferase-modified CHO fibroblasts in mice. (Surzyn M, Symes J, Medin JA, Sefton MV) Tissue Eng Part A 2009 Jan;15(1):127-36 |
| 1 | Liposome-mediated transfection with extract from neonatal rat cardiomyocytes induces transdifferentiation of human adipose-derived stem cells into cardiomyocytes. (Schimrosczyk K, Song YH, Vykoukal J, Vykoukal D, Bai X, Coleman M, Krohn A, Freyberg S, Alt EU) Scand J Clin Lab Invest 2008;68(6):464-72 8 Citations |
| 1 | Modulation of transcription parameters in glucocorticoid receptor-mediated repression. (Sun Y, Tao YG, Kagan BL, He Y, Simons SS Jr) Mol Cell Endocrinol 2008 Nov 25;295(1-2):59-69 23 Citations |
| 2 | Expression and function of fatty acid amide hydrolase in prostate cancer. (Endsley MP, Thill R, Choudhry I, Williams CL, Kajdacsy-Balla A, Campbell WB, Nithipatikom K) Int J Cancer 2008 Sep 15;123(6):1318-26 64 Citations |
| 1 | Constitutive CXCL12 expression induces anoikis in colorectal carcinoma cells. (Wendt MK, Drury LJ, Vongsa RA, Dwinell MB) Gastroenterology 2008 Aug;135(2):508-17 39 Citations |
| 1 | CHIP targets toxic alpha-Synuclein oligomers for degradation. (Tetzlaff JE, Putcha P, Outeiro TF, Ivanov A, Berezovska O, Hyman BT, McLean PJ) J Biol Chem 2008 Jun 27;283(26):17962-8 113 Citations |
| 2 | Identification and characterization of the unique guanine nucleotide exchange factor, SmgGDS, in vascular smooth muscle cells. (Thill R, Campbell WB, Williams CL) J Cell Biochem 2008 Aug 01;104(5):1760-70 5 Citations |
| 1 | Protein kinase A-dependent phosphorylation modulates beta1Pix guanine nucleotide exchange factor activity through 14-3-3beta binding. (Chahdi A, Sorokin A) Mol Cell Biol 2008 Mar;28(5):1679-87 35 Citations |
| 1 | Alternatively spliced human tissue factor promotes tumor growth and angiogenesis in a pancreatic cancer tumor model. (Hobbs JE, Zakarija A, Cundiff DL, Doll JA, Hymen E, Cornwell M, Crawford SE, Liu N, Signaevsky M, Soff GA) Thromb Res 2007;120 Suppl 2:S13-21 71 Citations |
| 1 | Apical membrane targeting and trafficking of the human proton-coupled transporter in polarized epithelia. (Subramanian VS, Marchant JS, Said HM) Am J Physiol Cell Physiol 2008 Jan;294(1):C233-40 36 Citations |
| 1 | SmgGDS regulates cell proliferation, migration, and NF-kappaB transcriptional activity in non-small cell lung carcinoma. (Tew GW, Lorimer EL, Berg TJ, Zhi H, Li R, Williams CL) J Biol Chem 2008 Jan 11;283(2):963-76 46 Citations |
| 1 | Domain 5 of the cation-independent mannose 6-phosphate receptor preferentially binds phosphodiesters (mannose 6-phosphate N-acetylglucosamine ester). (Chavez CA, Bohnsack RN, Kudo M, Gotschall RR, Canfield WM, Dahms NM) Biochemistry 2007 Nov 06;46(44):12604-17 40 Citations |
| 1 | The role of nitric oxide and the unfolded protein response in cytokine-induced beta-cell death. (Chambers KT, Unverferth JA, Weber SM, Wek RC, Urano F, Corbett JA) Diabetes 2008 Jan;57(1):124-32 63 Citations |
| 1 | The cardioprotective effect of mesenchymal stem cells is mediated by IGF-I and VEGF. (Sadat S, Gehmert S, Song YH, Yen Y, Bai X, Gaiser S, Klein H, Alt E) Biochem Biophys Res Commun 2007 Nov 23;363(3):674-9 244 Citations |
| 1 | Tight junction targeting and intracellular trafficking of occludin in polarized epithelial cells. (Subramanian VS, Marchant JS, Ye D, Ma TY, Said HM) Am J Physiol Cell Physiol 2007 Nov;293(5):C1717-26 26 Citations |
| 2 | p38alpha antagonizes p38gamma activity through c-Jun-dependent ubiquitin-proteasome pathways in regulating Ras transformation and stress response. (Qi X, Pohl NM, Loesch M, Hou S, Li R, Qin JZ, Cuenda A, Chen G) J Biol Chem 2007 Oct 26;282(43):31398-408 42 Citations |
| 1 | Human bullous pemphigoid antigen 2 transgenic skin elicits specific IgG in wild-type mice. (Olasz EB, Roh J, Yee CL, Arita K, Akiyama M, Shimizu H, Vogel JC, Yancey KB) J Invest Dermatol 2007 Dec;127(12):2807-17 28 Citations |
| 1 | Mutant ubiquitin found in Alzheimer's disease causes neuritic beading of mitochondria in association with neuronal degeneration. (Tan Z, Sun X, Hou FS, Oh HW, Hilgenberg LG, Hol EM, van Leeuwen FW, Smith MA, O'Dowd DK, Schreiber SS) Cell Death Differ 2007 Oct;14(10):1721-32 58 Citations |
| 1 | Minimal lipidation of pre-beta HDL by ABCA1 results in reduced ability to interact with ABCA1. (Mulya A, Lee JY, Gebre AK, Thomas MJ, Colvin PL, Parks JS) Arterioscler Thromb Vasc Biol 2007 Aug;27(8):1828-36 98 Citations |
| 1 | Vitamin B1 (thiamine) uptake by human retinal pigment epithelial (ARPE-19) cells: mechanism and regulation. (Subramanian VS, Mohammed ZM, Molina A, Marchant JS, Vaziri ND, Said HM) J Physiol 2007 Jul 01;582(Pt 1):73-85 24 Citations |
| 1 | Peroxisome proliferator-activated receptor gamma-independent suppression of androgen receptor expression by troglitazone mechanism and pharmacologic exploitation. (Yang CC, Wang YC, Wei S, Lin LF, Chen CS, Lee CC, Lin CC, Chen CS) Cancer Res 2007 Apr 01;67(7):3229-38 41 Citations |
| 1 | Engineered human tmpk/AZT as a novel enzyme/prodrug axis for suicide gene therapy. (Sato T, Neschadim A, Konrad M, Fowler DH, Lavie A, Medin JA) Mol Ther 2007 May;15(5):962-70 70 Citations |
| 1 | Targeting and intracellular trafficking of clinically relevant hTHTR1 mutations in human cell lines. (Subramanian VS, Marchant JS, Said HM) Clin Sci (Lond) 2007 Jul;113(2):93-102 12 Citations |
| 3 | Efficient transgenic rat production by a lentiviral vector. (Michalkiewicz M, Michalkiewicz T, Geurts AM, Roman RJ, Slocum GR, Singer O, Weihrauch D, Greene AS, Kaldunski M, Verma IM, Jacob HJ, Cowley AW Jr) Am J Physiol Heart Circ Physiol 2007 Jul;293(1):H881-94 35 Citations |
| 1 | Differential roles of Rap1 and Rap2 small GTPases in neurite retraction and synapse elimination in hippocampal spiny neurons. (Fu Z, Lee SH, Simonetta A, Hansen J, Sheng M, Pak DT) J Neurochem 2007 Jan;100(1):118-31 65 Citations |
| 1 | Prostate-derived factor as a paracrine and autocrine factor for the proliferation of androgen receptor-positive human prostate cancer cells. (Chen SJ, Karan D, Johansson SL, Lin FF, Zeckser J, Singh AP, Batra SK, Lin MF) Prostate 2007 Apr 01;67(5):557-71 58 Citations |
| 1 | Functional characterization of polymorphisms in the kidney enhancer of the human renin gene. (Itani HA, Liu X, Pratt JH, Sigmund CD) Endocrinology 2007 Mar;148(3):1424-30 17 Citations |
| 2 | Stress-induced c-Jun-dependent Vitamin D receptor (VDR) activation dissects the non-classical VDR pathway from the classical VDR activity. (Li QP, Qi X, Pramanik R, Pohl NM, Loesch M, Chen G) J Biol Chem 2007 Jan 19;282(3):1544-51 22 Citations |
| 2 | The cell-adhesion and signaling molecule PECAM-1 is a molecular mediator of resistance to genotoxic chemotherapy. (Bergom C, Goel R, Paddock C, Gao C, Newman DK, Matsuyama S, Newman PJ) Cancer Biol Ther 2006 Dec;5(12):1699-707 24 Citations |
| 1 | Genetic ablation of angiotensinogen in the subfornical organ of the brain prevents the central angiotensinergic pressor response. (Sinnayah P, Lazartigues E, Sakai K, Sharma RV, Sigmund CD, Davisson RL) Circ Res 2006 Nov 10;99(10):1125-31 35 Citations |
| 1 | Human papillomaviruses target the double-stranded RNA protein kinase pathway. (Hebner CM, Wilson R, Rader J, Bidder M, Laimins LA) J Gen Virol 2006 Nov;87(Pt 11):3183-93 47 Citations |
| 1 | Zinc induces ERK-dependent cell death through a specific Ras isoform. (Klein C, Creach K, Irintcheva V, Hughes KJ, Blackwell PL, Corbett JA, Baldassare JJ) Apoptosis 2006 Nov;11(11):1933-44 25 Citations |
| 1 | Proteomic analysis of acute promyelocytic leukemia: PML-RARalpha leads to decreased phosphorylation of OP18 at serine 63. (Zada AA, Geletu MH, Pulikkan JA, Müller-Tidow C, Reddy VA, Christopeit M, Hiddemann WD, Behre HM, Tenen DG, Behre G) Proteomics 2006 Nov;6(21):5705-19 11 Citations |
| 1 | FGF19 is a target for FOXC1 regulation in ciliary body-derived cells. (Tamimi Y, Skarie JM, Footz T, Berry FB, Link BA, Walter MA) Hum Mol Genet 2006 Nov 01;15(21):3229-40 31 Citations |
| 1 | Combination of PTEN gene therapy and radiation inhibits the growth of human prostate cancer xenografts. (Anai S, Goodison S, Shiverick K, Iczkowski K, Tanaka M, Rosser CJ) Hum Gene Ther 2006 Oct;17(10):975-84 35 Citations |
| 1 | A novel endothelial-specific heat shock protein HspA12B is required in both zebrafish development and endothelial functions in vitro. (Hu G, Tang J, Zhang B, Lin Y, Hanai J, Galloway J, Bedell V, Bahary N, Han Z, Ramchandran R, Thisse B, Thisse C, Zon LI, Sukhatme VP) J Cell Sci 2006 Oct 01;119(Pt 19):4117-26 49 Citations |
| 1 | Interleukin-1beta attenuates renin gene expression via a mitogen-activated protein kinase kinase-extracellular signal-regulated kinase and signal transducer and activator of transcription 3-dependent mechanism in As4.1 cells. (Liu X, Shi Q, Sigmund CD) Endocrinology 2006 Dec;147(12):6011-8 16 Citations |
| 1 | TSC2 integrates Wnt and energy signals via a coordinated phosphorylation by AMPK and GSK3 to regulate cell growth. (Inoki K, Ouyang H, Zhu T, Lindvall C, Wang Y, Zhang X, Yang Q, Bennett C, Harada Y, Stankunas K, Wang CY, He X, MacDougald OA, You M, Williams BO, Guan KL) Cell 2006 Sep 08;126(5):955-68 875 Citations |
| 2 | p38gamma mitogen-activated protein kinase integrates signaling crosstalk between Ras and estrogen receptor to increase breast cancer invasion. (Qi X, Tang J, Loesch M, Pohl N, Alkan S, Chen G) Cancer Res 2006 Aug 01;66(15):7540-7 32 Citations |
| 1 | Activation of mammalian target of rapamycin signaling pathway contributes to tumor cell survival in anaplastic lymphoma kinase-positive anaplastic large cell lymphoma. (Vega F, Medeiros LJ, Leventaki V, Atwell C, Cho-Vega JH, Tian L, Claret FX, Rassidakis GZ) Cancer Res 2006 Jul 01;66(13):6589-97 162 Citations |
| 1 | Effects of acetylation, polymerase phosphorylation, and DNA unwinding in glucocorticoid receptor transactivation. (Kim Y, Sun Y, Chow C, Pommier YG, Simons SS Jr) J Steroid Biochem Mol Biol 2006 Jul;100(1-3):3-17 22 Citations |
| 1 | Transcriptional regulation of the human hepatic lipase (LIPC) gene promoter. (Rufibach LE, Duncan SA, Battle M, Deeb SS) J Lipid Res 2006 Jul;47(7):1463-77 30 Citations |
| 1 | Co-activation of atrial natriuretic factor promoter by Tip60 and serum response factor. (Kim MS, Merlo X, Wilson C, Lough J) J Biol Chem 2006 Jun 02;281(22):15082-9 13 Citations |
| 1 | Robo4 signaling in endothelial cells implies attraction guidance mechanisms. (Kaur S, Castellone MD, Bedell VM, Konar M, Gutkind JS, Ramchandran R) J Biol Chem 2006 Apr 21;281(16):11347-56 73 Citations |
| 1 | Targeting and trafficking of the human thiamine transporter-2 in epithelial cells. (Subramanian VS, Marchant JS, Said HM) J Biol Chem 2006 Feb 24;281(8):5233-45 26 Citations |
| 1 | Discovery of small molecule inhibitors of the interaction of the thyroid hormone receptor with transcriptional coregulators. (Arnold LA, Estébanez-Perpiñá E, Togashi M, Jouravel N, Shelat A, McReynolds AC, Mar E, Nguyen P, Baxter JD, Fletterick RJ, Webb P, Guy RK) J Biol Chem 2005 Dec 30;280(52):43048-55 85 Citations |
| 1 | Transgenic expression of a dominant-negative ASIC3 subunit leads to increased sensitivity to mechanical and inflammatory stimuli. (Mogil JS, Breese NM, Witty MF, Ritchie J, Rainville ML, Ase A, Abbadi N, Stucky CL, Séguéla P) J Neurosci 2005 Oct 26;25(43):9893-901 98 Citations |
| 2 | Sepiapterin attenuates 1-methyl-4-phenylpyridinium-induced apoptosis in neuroblastoma cells transfected with neuronal NOS: role of tetrahydrobiopterin, nitric oxide, and proteasome activation. (Shang T, Kotamraju S, Zhao H, Kalivendi SV, Hillard CJ, Kalyanaraman B) Free Radic Biol Med 2005 Oct 15;39(8):1059-74 27 Citations |
| 2 | Maternal alloimmunization against the rare platelet-specific antigen HPA-9b (Max a) is an important cause of neonatal alloimmune thrombocytopenia. (Peterson JA, Balthazor SM, Curtis BR, McFarland JG, Aster RH) Transfusion 2005 Sep;45(9):1487-95 44 Citations |
| 1 | Neuroblastoma cells transiently transfected to simultaneously express the co-stimulatory molecules CD54, CD80, CD86, and CD137L generate antitumor immunity in mice. (Johnson BD, Gershan JA, Natalia N, Zujewski H, Weber JJ, Yan X, Orentas RJ) J Immunother 2005 Sep-Oct;28(5):449-60 30 Citations |
| 1 | Specific pharmacological dimerization of KDR in lentivirally transduced human hematopoietic cells activates anti-apoptotic and proliferative mechanisms. (Siatskas C, Underwood J, Ramezani A, Hawley RG, Medin JA) FASEB J 2005 Oct;19(12):1752-4 9 Citations |
| 1 | Overexpression of neuropilin-1 promotes constitutive MAPK signalling and chemoresistance in pancreatic cancer cells. (Wey JS, Gray MJ, Fan F, Belcheva A, McCarty MF, Stoeltzing O, Somcio R, Liu W, Evans DB, Klagsbrun M, Gallick GE, Ellis LM) Br J Cancer 2005 Jul 25;93(2):233-41 90 Citations |
| 1 | HSP70 binding modulates detachment of Na-K-ATPase following energy deprivation in renal epithelial cells. (Riordan M, Sreedharan R, Wang S, Thulin G, Mann A, Stankewich M, Van Why S, Kashgarian M, Siegel NJ) Am J Physiol Renal Physiol 2005 Jun;288(6):F1236-42 36 Citations |
| 2 | Stat5 promotes homotypic adhesion and inhibits invasive characteristics of human breast cancer cells. (Sultan AS, Xie J, LeBaron MJ, Ealley EL, Nevalainen MT, Rui H) Oncogene 2005 Jan 27;24(5):746-60 143 Citations |
| 1 | IFI16 is an essential mediator of growth inhibition, but not differentiation, induced by the leukemia inhibitory factor/JAK/STAT pathway in medullary thyroid carcinoma cells. (Kim EJ, Park JI, Nelkin BD) J Biol Chem 2005 Feb 11;280(6):4913-20 38 Citations |
| 1 | Unanticipated antigens: translation initiation at CUG with leucine. (Schwab SR, Shugart JA, Horng T, Malarkannan S, Shastri N) PLoS Biol 2004 Nov;2(11):e366 73 Citations |
| 1 | Leucine culture reveals that ATP synthase functions as a fuel sensor in pancreatic beta-cells. (Yang J, Wong RK, Wang X, Moibi J, Hessner MJ, Greene S, Wu J, Sukumvanich S, Wolf BA, Gao Z) J Biol Chem 2004 Dec 24;279(52):53915-23 24 Citations |
| 1 | Hairy-related transcription factors inhibit GATA-dependent cardiac gene expression through a signal-responsive mechanism. (Kathiriya IS, King IN, Murakami M, Nakagawa M, Astle JM, Gardner KA, Gerard RD, Olson EN, Srivastava D, Nakagawa O) J Biol Chem 2004 Dec 24;279(52):54937-43 55 Citations |
| 1 | Metafectene is superior to lipofectamine in the transfection of G(s) alpha prostate cancer cells. (Iczkowski KA, Omara-Opyene AL, Klösel R) Mol Biotechnol 2004 Oct;28(2):97-103 7 Citations |
| 1 | Calcium-dependent dephosphorylation mediates the hyperosmotic and lysophosphatidic acid-dependent inhibition of natriuretic peptide receptor-B/guanylyl cyclase-B. (Potthast R, Abbey-Hosch SE, Antos LK, Marchant JS, Kuhn M, Potter LR) J Biol Chem 2004 Nov 19;279(47):48513-9 29 Citations |
| 1 | PXR (NR1I2): splice variants in human tissues, including brain, and identification of neurosteroids and nicotine as PXR activators. (Lamba V, Yasuda K, Lamba JK, Assem M, Davila J, Strom S, Schuetz EG) Toxicol Appl Pharmacol 2004 Sep 15;199(3):251-65 143 Citations |
| 1 | Protein tyrosine phosphatase receptor-type O (PTPRO) exhibits characteristics of a candidate tumor suppressor in human lung cancer. (Motiwala T, Kutay H, Ghoshal K, Bai S, Seimiya H, Tsuruo T, Suster S, Morrison C, Jacob ST) Proc Natl Acad Sci U S A 2004 Sep 21;101(38):13844-9 86 Citations |
| 1 | Arachidonic acid-induced carbon-centered radicals and phospholipid peroxidation in cyclo-oxygenase-2-transfected PC12 cells. (Jiang J, Borisenko GG, Osipov A, Martin I, Chen R, Shvedova AA, Sorokin A, Tyurina YY, Potapovich A, Tyurin VA, Graham SH, Kagan VE) J Neurochem 2004 Sep;90(5):1036-49 55 Citations |
| 1 | ExoS Rho GTPase-activating protein activity stimulates reorganization of the actin cytoskeleton through Rho GTPase guanine nucleotide disassociation inhibitor. (Sun J, Barbieri JT) J Biol Chem 2004 Oct 08;279(41):42936-44 26 Citations |
| 1 | Autologous vascular smooth muscle cell-based myocardial gene therapy to induce coronary collateral growth. (Hattan N, Warltier D, Gu W, Kolz C, Chilian WM, Weihrauch D) Am J Physiol Heart Circ Physiol 2004 Aug;287(2):H488-93 23 Citations |
| 1 | Aberrant regulation of survivin by the RB/E2F family of proteins. (Jiang Y, Saavedra HI, Holloway MP, Leone G, Altura RA) J Biol Chem 2004 Sep 24;279(39):40511-20 140 Citations |
| 1 | Two regions promote U11 small nuclear ribonucleoprotein particle binding to a retroviral splicing inhibitor element (negative regulator of splicing). (McNally LM, Yee L, McNally MT) J Biol Chem 2004 Sep 10;279(37):38201-8 8 Citations |
| 1 | Ezrin/radixin/moesin proteins are high affinity targets for ADP-ribosylation by Pseudomonas aeruginosa ExoS. (Maresso AW, Baldwin MR, Barbieri JT) J Biol Chem 2004 Sep 10;279(37):38402-8 51 Citations |
| 1 | Localization and function of the brain excitatory amino acid transporter type 1 in cardiac mitochondria. (Ralphe JC, Segar JL, Schutte BC, Scholz TD) J Mol Cell Cardiol 2004 Jul;37(1):33-41 30 Citations |
| 1 | The 3'-untranslated region of the beta2-adrenergic receptor mRNA regulates receptor synthesis. (Subramaniam K, Chen K, Joseph K, Raymond JR, Tholanikunnel BG) J Biol Chem 2004 Jun 25;279(26):27108-15 26 Citations |
| 2 | Quality control in the apoA-I secretory pathway: deletion of apoA-I helix 6 leads to the formation of cytosolic phospholipid inclusions. (Bhat S, Zabalawi M, Willingham MC, Shelness GS, Thomas MJ, Sorci-Thomas MG) J Lipid Res 2004 Jul;45(7):1207-20 9 Citations |
| 2 | p38 MAPK activation selectively induces cell death in K-ras-mutated human colon cancer cells through regulation of vitamin D receptor. (Qi X, Tang J, Pramanik R, Schultz RM, Shirasawa S, Sasazuki T, Han J, Chen G) J Biol Chem 2004 May 21;279(21):22138-44 52 Citations |
| 1 | Interactions between hepatic Mrp4 and Sult2a as revealed by the constitutive androstane receptor and Mrp4 knockout mice. (Assem M, Schuetz EG, Leggas M, Sun D, Yasuda K, Reid G, Zelcer N, Adachi M, Strom S, Evans RM, Moore DD, Borst P, Schuetz JD) J Biol Chem 2004 May 21;279(21):22250-7 206 Citations |
| 1 | Analysis of two translocation breakpoints and identification of a negative regulatory element in patients with Rieger's syndrome. (Trembath DG, Semina EV, Jones DH, Patil SR, Qian Q, Amendt BA, Russo AF, Murray JC) Birth Defects Res A Clin Mol Teratol 2004 Feb;70(2):82-91 16 Citations |
| 1 | Calmodulin interacts with the third intracellular loop of the serotonin 5-hydroxytryptamine1A receptor at two distinct sites: putative role in receptor phosphorylation by protein kinase C. (Turner JH, Gelasco AK, Raymond JR) J Biol Chem 2004 Apr 23;279(17):17027-37 65 Citations |
| 2 | Alpha-synuclein up-regulation and aggregation during MPP+-induced apoptosis in neuroblastoma cells: intermediacy of transferrin receptor iron and hydrogen peroxide. (Kalivendi SV, Cunningham S, Kotamraju S, Joseph J, Hillard CJ, Kalyanaraman B) J Biol Chem 2004 Apr 09;279(15):15240-7 107 Citations |
| 1 | Membrane-potential-dependent inhibition of platelet adhesion to endothelial cells by epoxyeicosatrienoic acids. (Krötz F, Riexinger T, Buerkle MA, Nithipatikom K, Gloe T, Sohn HY, Campbell WB, Pohl U) Arterioscler Thromb Vasc Biol 2004 Mar;24(3):595-600 96 Citations |
| 1 | Comparison of immune responses and protective efficacy of suicidal DNA vaccine and conventional DNA vaccine encoding glycoprotein C of pseudorabies virus in mice. (Xiao S, Chen H, Fang L, Liu C, Zhang H, Jiang Y, Hong W) Vaccine 2004 Jan 02;22(3-4):345-51 50 Citations |
| 2 | Estrogen receptor inhibits c-Jun-dependent stress-induced cell death by binding and modifying c-Jun activity in human breast cancer cells. (Qi X, Borowicz S, Pramanik R, Schultz RM, Han J, Chen G) J Biol Chem 2004 Feb 20;279(8):6769-77 26 Citations |
| 1 | Expression and functional contribution of hTHTR-2 in thiamin absorption in human intestine. (Said HM, Balamurugan K, Subramanian VS, Marchant JS) Am J Physiol Gastrointest Liver Physiol 2004 Mar;286(3):G491-8 82 Citations |
| 1 | Phosphorylation of threonine 497 in endothelial nitric-oxide synthase coordinates the coupling of L-arginine metabolism to efficient nitric oxide production. (Lin MI, Fulton D, Babbitt R, Fleming I, Busse R, Pritchard KA Jr, Sessa WC) J Biol Chem 2003 Nov 07;278(45):44719-26 194 Citations |
| 1 | JUMONJI, a critical factor for cardiac development, functions as a transcriptional repressor. (Kim TG, Kraus JC, Chen J, Lee Y) J Biol Chem 2003 Oct 24;278(43):42247-55 74 Citations |
| 1 | Identification and characterization of E2F7, a novel mammalian E2F family member capable of blocking cellular proliferation. (de Bruin A, Maiti B, Jakoi L, Timmers C, Buerki R, Leone G) J Biol Chem 2003 Oct 24;278(43):42041-9 148 Citations |
| 1 | CrkIII: a novel and biologically distinct member of the Crk family of adaptor proteins. (Prosser S, Sorokina E, Pratt P, Sorokin A) Oncogene 2003 Jul 31;22(31):4799-806 23 Citations |
| 1 | A carboxy-terminal region of the hepatitis B virus X protein promotes DNA interaction of CREB and mimics the native protein for transactivation function. (Reddi H, Kumar R, Jain SK, Kumar V) Virus Genes 2003 May;26(3):227-38 12 Citations |
| 1 | Gene transfer into genomes of human cells by the sleeping beauty transposon system. (Geurts AM, Yang Y, Clark KJ, Liu G, Cui Z, Dupuy AJ, Bell JB, Largaespada DA, Hackett PB) Mol Ther 2003 Jul;8(1):108-17 277 Citations |
| 1 | Polycystin-1 distribution is modulated by polycystin-2 expression in mammalian cells. (Grimm DH, Cai Y, Chauvet V, Rajendran V, Zeltner R, Geng L, Avner ED, Sweeney W, Somlo S, Caplan MJ) J Biol Chem 2003 Sep 19;278(38):36786-93 69 Citations |
| 1 | BMP-7 counteracts TGF-beta1-induced epithelial-to-mesenchymal transition and reverses chronic renal injury. (Zeisberg M, Hanai J, Sugimoto H, Mammoto T, Charytan D, Strutz F, Kalluri R) Nat Med 2003 Jul;9(7):964-8 1049 Citations |
| 1 | Dual expression of CD80 and CD86 produces a tumor vaccine superior to single expression of either molecule. (Johnson BD, Yan X, Schauer DW, Orentas RJ) Cell Immunol 2003 Mar;222(1):15-26 24 Citations |
| 1 | Expression of the hemochromatosis (HFE) gene modulates the cellular uptake of 67Ga. (Chitambar CR, Wereley JP) J Nucl Med 2003 Jun;44(6):943-6 8 Citations |
| 1 | Peroxisome proliferator-activated receptor alpha (PPARalpha) agonist treatment reverses PPARalpha dysfunction and abnormalities in hepatic lipid metabolism in ethanol-fed mice. (Fischer M, You M, Matsumoto M, Crabb DW) J Biol Chem 2003 Jul 25;278(30):27997-8004 203 Citations |
| 1 | Localized recruitment of a chromatin-remodeling activity by an activator in vivo drives transcriptional elongation. (Corey LL, Weirich CS, Benjamin IJ, Kingston RE) Genes Dev 2003 Jun 01;17(11):1392-401 108 Citations |
| 3 | Expression of human factor VIII under control of the platelet-specific alphaIIb promoter in megakaryocytic cell line as well as storage together with VWF. (Shi Q, Wilcox DA, Fahs SA, Kroner PA, Montgomery RR) Mol Genet Metab 2003 May;79(1):25-33 37 Citations |
| 2 | AP-4F, antennapedia peptide linked to an amphipathic alpha helical peptide, increases the efficiency of Lipofectamine-mediated gene transfection in endothelial cells. (Ou J, Geiger T, Ou Z, Ackerman AW, Oldham KT, Pritchard KA Jr) Biochem Biophys Res Commun 2003 Jun 06;305(3):605-10 15 Citations |
| 1 | Bleeding due to disruption of a cargo-specific ER-to-Golgi transport complex. (Zhang B, Cunningham MA, Nichols WC, Bernat JA, Seligsohn U, Pipe SW, McVey JH, Schulte-Overberg U, de Bosch NB, Ruiz-Saez A, White GC, Tuddenham EG, Kaufman RJ, Ginsburg D) Nat Genet 2003 Jun;34(2):220-5 200 Citations |
| 1 | The absence of functional glucosylceramide synthase does not sensitize melanoma cells for anticancer drugs. (Veldman RJ, Mita A, Cuvillier O, Garcia V, Klappe K, Medin JA, Campbell JD, Carpentier S, Kok JW, Levade T) FASEB J 2003 Jun;17(9):1144-6 39 Citations |
| 1 | The CBP bromodomain and nucleosome targeting are required for Zta-directed nucleosome acetylation and transcription activation. (Deng Z, Chen CJ, Chamberlin M, Lu F, Blobel GA, Speicher D, Cirillo LA, Zaret KS, Lieberman PM) Mol Cell Biol 2003 Apr;23(8):2633-44 41 Citations |
| 1 | Inhibition of the cardiac alpha-actin gene in embryonic cardiac myocytes by dominant-negative serum response factor. (Zhu X, McAllister D, Lough J) Anat Rec A Discov Mol Cell Evol Biol 2003 Apr;271(2):315-21 1 Citation |
| 1 | Efficiency of chimeraplast gene targeting by direct nuclear injection using a GFP recovery assay. (Tran ND, Liu X, Yan Z, Abbote D, Jiang Q, Kmiec EB, Sigmund CD, Engelhardt JF) Mol Ther 2003 Feb;7(2):248-53 34 Citations |
| 1 | Bcl-2 reduces mutant rates in a transgenic lacZ reporter gene in mouse pre-B lymphocytes. (Felix K, Rolink A, Melchers F, Janz S) Mutat Res 2003 Jan 28;522(1-2):135-44 3 Citations |
| 1 | Hsp27 associates with actin and limits injury in energy depleted renal epithelia. (Van Why SK, Mann AS, Ardito T, Thulin G, Ferris S, Macleod MA, Kashgarian M, Siegel NJ) J Am Soc Nephrol 2003 Jan;14(1):98-106 44 Citations |
| 1 | Suppression of tumorigenesis and induction of p15(ink4b) by Smad4/DPC4 in human pancreatic cancer cells. (Peng B, Fleming JB, Breslin T, Grau AM, Fojioka S, Abbruzzese JL, Evans DB, Ayers D, Wathen K, Wu T, Robertson KD, Chiao PJ) Clin Cancer Res 2002 Nov;8(11):3628-38 54 Citations |
| 1 | Critical independent regions in the VWF propeptide and mature VWF that enable normal VWF storage. (Haberichter SL, Jacobi P, Montgomery RR) Blood 2003 Feb 15;101(4):1384-91 36 Citations |
| 2 | Endothelin signalling and regulation of protein kinases in glomerular mesangial cells. (Sorokin A, Foschi M, Dunn MJ) Clin Sci (Lond) 2002 Aug;103 Suppl 48:132S-136S 13 Citations |
| 1 | Prostaglandin-E2 enhances EPO-mediated STAT5 transcriptional activity by serine phosphorylation of CREB. (Boer AK, Drayer AL, Rui H, Vellenga E) Blood 2002 Jul 15;100(2):467-73 39 Citations |
| 1 | Intracellular trafficking and membrane targeting mechanisms of the human reduced folate carrier in Mammalian epithelial cells. (Marchant JS, Subramanian VS, Parker I, Said HM) J Biol Chem 2002 Sep 06;277(36):33325-33 34 Citations |
| 1 | The activation of Rac1 by M3 muscarinic acetylcholine receptors involves the translocation of Rac1 and IQGAP1 to cell junctions and changes in the composition of protein complexes containing Rac1, IQGAP1, and actin. (Ruiz-Velasco R, Lanning CC, Williams CL) J Biol Chem 2002 Sep 06;277(36):33081-91 18 Citations |
| 1 | The cysteine knot of platelet glycoprotein Ib beta (GPIb beta) is critical for the interaction of GPIb beta with GPIX. (Kenny D, Morateck PA, Montgomery RR) Blood 2002 Jun 15;99(12):4428-33 16 Citations |
| 1 | Involvement of the muscarinic acetylcholine receptor in inhibition of cell migration. (Varker KA, Williams CL) Biochem Pharmacol 2002 Feb 15;63(4):597-605 8 Citations |
| 1 | Differential regulation of gene expression by PITX2 isoforms. (Cox CJ, Espinoza HM, McWilliams B, Chappell K, Morton L, Hjalt TA, Semina EV, Amendt BA) J Biol Chem 2002 Jul 12;277(28):25001-10 116 Citations |
| 1 | The 5-HT3 subtype of serotonin receptor contributes to nociceptive processing via a novel subset of myelinated and unmyelinated nociceptors. (Zeitz KP, Guy N, Malmberg AB, Dirajlal S, Martin WJ, Sun L, Bonhaus DW, Stucky CL, Julius D, Basbaum AI) J Neurosci 2002 Feb 01;22(3):1010-9 287 Citations |
| 2 | Role of tyrosine kinase Jak2 in prolactin-induced differentiation and growth of mammary epithelial cells. (Xie J, LeBaron MJ, Nevalainen MT, Rui H) J Biol Chem 2002 Apr 19;277(16):14020-30 36 Citations |
| 1 | Endostatin causes G1 arrest of endothelial cells through inhibition of cyclin D1. (Hanai J, Dhanabal M, Karumanchi SA, Albanese C, Waterman M, Chan B, Ramchandran R, Pestell R, Sukhatme VP) J Biol Chem 2002 May 10;277(19):16464-9 205 Citations |
| 1 | Basolateral sorting signal of the 300-kDa mannose 6-phosphate receptor. (Wick DA, Seetharam B, Dahms NM) Am J Physiol Gastrointest Liver Physiol 2002 Jan;282(1):G51-60 8 Citations |
| 1 | Serine phosphorylation of GH-activated signal transducer and activator of transcription 5a (STAT5a) and STAT5b: impact on STAT5 transcriptional activity. (Park SH, Yamashita H, Rui H, Waxman DJ) Mol Endocrinol 2001 Dec;15(12):2157-71 57 Citations |
| 1 | Reduced expression of Wnt-1 and E-cadherin, and diminished beta-catenin stability in MCF-7 breast cancer cells that overexpress protein kinase C-alpha. (Williams CL, Noti JD) Int J Oncol 2001 Dec;19(6):1227-33 7 Citations |
| 1 | Intracellular trafficking/membrane targeting of human reduced folate carrier expressed in Xenopus oocytes. (Subramanian VS, Marchant JS, Parker I, Said HM) Am J Physiol Gastrointest Liver Physiol 2001 Dec;281(6):G1477-86 26 Citations |
| 1 | PU.1/Spi-B regulation of c-rel is essential for mature B cell survival. (Hu CJ, Rao S, Ramirez-Bergeron DL, Garrett-Sinha LA, Gerondakis S, Clark MR, Simon MC) Immunity 2001 Oct;15(4):545-55 40 Citations |
| 1 | NF-Y antagonizes renin enhancer function by blocking stimulatory transcription factors. (Shi Q, Gross KW, Sigmund CD) Hypertension 2001 Sep;38(3):332-6 30 Citations |
| 1 | Myc requires distinct E2F activities to induce S phase and apoptosis. (Leone G, Sears R, Huang E, Rempel R, Nuckolls F, Park CH, Giangrande P, Wu L, Saavedra HI, Field SJ, Thompson MA, Yang H, Fujiwara Y, Greenberg ME, Orkin S, Smith C, Nevins JR) Mol Cell 2001 Jul;8(1):105-13 181 Citations |
| 1 | Disrupted bile acid homeostasis reveals an unexpected interaction among nuclear hormone receptors, transporters, and cytochrome P450. (Schuetz EG, Strom S, Yasuda K, Lecureur V, Assem M, Brimer C, Lamba J, Kim RB, Ramachandran V, Komoroski BJ, Venkataramanan R, Cai H, Sinal CJ, Gonzalez FJ, Schuetz JD) J Biol Chem 2001 Oct 19;276(42):39411-8 338 Citations |
| 1 | HIF-1alpha binding to VHL is regulated by stimulus-sensitive proline hydroxylation. (Yu F, White SB, Zhao Q, Lee FS) Proc Natl Acad Sci U S A 2001 Aug 14;98(17):9630-5 587 Citations |
| 2 | PreproEndothelin-1 expression in human mesangial cells: evidence for a p38 mitogen-activated protein kinase/protein kinases-C-dependent mechanism. (Foschi M, Sorokin A, Pratt P, McGinty A, La Villa G, Franchi F, Dunn MJ) J Am Soc Nephrol 2001 Jun;12(6):1137-50 16 Citations |
| 1 | Dynamic, site-specific interaction of hypoxia-inducible factor-1alpha with the von Hippel-Lindau tumor suppressor protein. (Yu F, White SB, Zhao Q, Lee FS) Cancer Res 2001 May 15;61(10):4136-42 73 Citations |
| 1 | Characterisation of Wnt gene expression during the differentiation of murine embryonic stem cells in vitro: role of Wnt3 in enhancing haematopoietic differentiation. (Lako M, Lindsay S, Lincoln J, Cairns PM, Armstrong L, Hole N) Mech Dev 2001 May;103(1-2):49-59 67 Citations |
| 2 | Inhibition of antigen-receptor signaling by Platelet Endothelial Cell Adhesion Molecule-1 (CD31) requires functional ITIMs, SHP-2, and p56(lck). (Newman DK, Hamilton C, Newman PJ) Blood 2001 Apr 15;97(8):2351-7 106 Citations |
| 1 | Protein-tyrosine kinase Pyk2 mediates endothelin-induced p38 MAPK activation in glomerular mesangial cells. (Sorokin A, Kozlowski P, Graves L, Philip A) J Biol Chem 2001 Jun 15;276(24):21521-8 62 Citations |
| 1 | Transient ectopic expression of PTEN in thyroid cancer cell lines induces cell cycle arrest and cell type-dependent cell death. (Weng LP, Gimm O, Kum JB, Smith WM, Zhou XP, Wynford-Thomas D, Leone G, Eng C) Hum Mol Genet 2001 Feb 01;10(3):251-8 78 Citations |
| 1 | Platelet activation by a relapsing fever spirochaete results in enhanced bacterium-platelet interaction via integrin alphaIIbbeta3 activation. (Alugupalli KR, Michelson AD, Barnard MR, Robbins D, Coburn J, Baker EK, Ginsberg MH, Schwan TG, Leong JM) Mol Microbiol 2001 Jan;39(2):330-40 33 Citations |
| 1 | The cellular uptake of anandamide is coupled to its breakdown by fatty-acid amide hydrolase. (Deutsch DG, Glaser ST, Howell JM, Kunz JS, Puffenbarger RA, Hillard CJ, Abumrad N) J Biol Chem 2001 Mar 09;276(10):6967-73 191 Citations |
| 1 | Identification of CD8+ T-cell-stimulating antigen genes in cDNA libraries. (Mendoza LM, Malarkannan S, Shastri N) Methods Mol Biol 2001;156:255-63 3 Citations |
| 1 | Retinoic acid-mediated activation of the mouse renin enhancer. (Shi Q, Gross KW, Sigmund CD) J Biol Chem 2001 Feb 02;276(5):3597-603 54 Citations |
| 1 | Adenovirus E1A oncogene expression in tumor cells enhances killing by TNF-related apoptosis-inducing ligand (TRAIL). (Routes JM, Ryan S, Clase A, Miura T, Kuhl A, Potter TA, Cook JL) J Immunol 2000 Oct 15;165(8):4522-7 62 Citations |
| 1 | P2Y2 purinergic and M3 muscarinic acetylcholine receptors activate different phospholipase C-beta isoforms that are uniquely susceptible to protein kinase C-dependent phosphorylation and inactivation. (Strassheim D, Williams CL) J Biol Chem 2000 Dec 15;275(50):39767-72 46 Citations |
| 1 | Pseudomonas aeruginosa ExoT is a Rho GTPase-activating protein. (Krall R, Schmidt G, Aktories K, Barbieri JT) Infect Immun 2000 Oct;68(10):6066-8 126 Citations |
| 1 | The p38 pathway provides negative feedback for Ras proliferative signaling. (Chen G, Hitomi M, Han J, Stacey DW) J Biol Chem 2000 Dec 15;275(50):38973-80 142 Citations |
| 1 | A (GATA)(7) motif located in the 5' boundary area of the human beta-globin locus control region exhibits silencer activity in erythroid cells. (Ramchandran R, Bengra C, Whitney B, Lanclos K, Tuan D) Am J Hematol 2000 Sep;65(1):14-24 18 Citations |
| 1 | Surface expression of glycoprotein ib alpha is dependent on glycoprotein ib beta: evidence from a novel mutation causing Bernard-Soulier syndrome. (Moran N, Morateck PA, Deering A, Ryan M, Montgomery RR, Fitzgerald DJ, Kenny D) Blood 2000 Jul 15;96(2):532-9 54 Citations |
| 1 | Interactions between von Willebrand factor and Factor VIII: where did they first meet. (Montgomery RR, Gill JC) J Pediatr Hematol Oncol 2000 May-Jun;22(3):269-75 33 Citations |
| 2 | Megakaryocyte-targeted synthesis of the integrin beta(3)-subunit results in the phenotypic correction of Glanzmann thrombasthenia. (Wilcox DA, Olsen JC, Ishizawa L, Bray PF, French DL, Steeber DA, Bell WR, Griffith M, White GC 2nd) Blood 2000 Jun 15;95(12):3645-51 44 Citations |
| 1 | Regulator of G protein signaling RGS3T is localized to the nucleus and induces apoptosis. (Dulin NO, Pratt P, Tiruppathi C, Niu J, Voyno-Yasenetskaya T, Dunn MJ) J Biol Chem 2000 Jul 14;275(28):21317-23 62 Citations |
| 1 | 5-Hydroxytryptamine1A receptor/Gibetagamma stimulates mitogen-activated protein kinase via NAD(P)H oxidase and reactive oxygen species upstream of src in chinese hamster ovary fibroblasts. (Mukhin YV, Garnovskaya MN, Collinsworth G, Grewal JS, Pendergrass D, Nagai T, Pinckney S, Greene EL, Raymond JR) Biochem J 2000 Apr 01;347 Pt 1:61-7 64 Citations |
| 1 | Expression and function of calcium binding domain chimeras of the integrins alpha(IIb) and alpha(5). (Gidwitz S, Lyman S, White GC 2nd) J Biol Chem 2000 Mar 03;275(9):6680-8 4 Citations |
| 1 | Canstatin, a novel matrix-derived inhibitor of angiogenesis and tumor growth. (Kamphaus GD, Colorado PC, Panka DJ, Hopfer H, Ramchandran R, Torre A, Maeshima Y, Mier JW, Sukhatme VP, Kalluri R) J Biol Chem 2000 Jan 14;275(2):1209-15 376 Citations |
| 1 | Murine CCR9, a chemokine receptor for thymus-expressed chemokine that is up-regulated following pre-TCR signaling. (Norment AM, Bogatzki LY, Gantner BN, Bevan MJ) J Immunol 2000 Jan 15;164(2):639-48 88 Citations |
| 1 | Herpes simplex thymidine kinase (HStk) transgenic donor lymphocytes. (Burt RK, Drobyski WR, Traynor AE, Link CJ Jr) Bone Marrow Transplant 1999 Nov;24(10):1043-51 5 Citations |
| 1 | Calcium ionophore upregulation of AUUUA-specific binding protein activity is contemporaneous with granulocyte macrophage colony-stimulating factor messenger RNA stabilization in AML14.3D10 cells. (Ruth JH, Esnault S, Jarzembowski JA, Malter JS) Am J Respir Cell Mol Biol 1999 Nov;21(5):621-8 18 Citations |
| 1 | The recombinant 5-HT1A receptor: G protein coupling and signalling pathways. (Raymond JR, Mukhin YV, Gettys TW, Garnovskaya MN) Br J Pharmacol 1999 Aug;127(8):1751-64 193 Citations |
| 2 | Integrin alphaIIb promoter-targeted expression of gene products in megakaryocytes derived from retrovirus-transduced human hematopoietic cells. (Wilcox DA, Olsen JC, Ishizawa L, Griffith M, White GC 2nd) Proc Natl Acad Sci U S A 1999 Aug 17;96(17):9654-9 47 Citations |
| 1 | Pseudomonas aeruginosa exoenzyme S disrupts Ras-mediated signal transduction by inhibiting guanine nucleotide exchange factor-catalyzed nucleotide exchange. (Ganesan AK, Vincent TS, Olson JC, Barbieri JT) J Biol Chem 1999 Jul 30;274(31):21823-9 65 Citations |
| 1 | Rapid, economical filter alternative to chromosomal DNA centrifugation in the alkaline lysis plasmid protocol. (McNally MT) Biotechniques 1999 Jul;27(1):68-71 |
| 1 | Presentation of out-of-frame peptide/MHC class I complexes by a novel translation initiation mechanism. (Malarkannan S, Horng T, Shih PP, Schwab S, Shastri N) Immunity 1999 Jun;10(6):681-90 81 Citations |
| 1 | Enzymatic and functional correction along with long-term enzyme secretion from transduced bone marrow hematopoietic stem/progenitor and stromal cells derived from patients with Fabry disease. (Takenaka T, Hendrickson CS, Tworek DM, Tudor M, Schiffmann R, Brady RO, Medin JA) Exp Hematol 1999 Jul;27(7):1149-59 32 Citations |
| 1 | Overexpression of protein kinase C-alpha in MCF-7 breast cancer cells results in differential regulation and expression of alphavbeta3 and alphavbeta5. (Carey I, Williams CL, Ways DK, Noti JD) Int J Oncol 1999 Jul;15(1):127-36 19 Citations |
| 2 | Synthesis and characterization of potent and selective agonists of the neuronal cannabinoid receptor (CB1). (Hillard CJ, Manna S, Greenberg MJ, DiCamelli R, Ross RA, Stevenson LA, Murphy V, Pertwee RG, Campbell WB) J Pharmacol Exp Ther 1999 Jun;289(3):1427-33 284 Citations |
| 1 | Enrichment of transiently transfected mesangial cells by cell sorting after cotransfection with GFP. (Chen R, Greene EL, Collinsworth G, Grewal JS, Houghton O, Zeng H, Garnovskaya M, Paul RV, Raymond JR) Am J Physiol 1999 05;276(5):F777-85 13 Citations |
| 1 | Basic fibroblast growth factor activates serum response factor gene expression by multiple distinct signaling mechanisms. (Spencer JA, Major ML, Misra RP) Mol Cell Biol 1999 Jun;19(6):3977-88 18 Citations |
| 2 | The amino-terminal domain of Pseudomonas aeruginosa ExoS disrupts actin filaments via small-molecular-weight GTP-binding proteins. (Pederson KJ, Vallis AJ, Aktories K, Frank DW, Barbieri JT) Mol Microbiol 1999 Apr;32(2):393-401 112 Citations |
| 1 | The critical interaction of glycoprotein (GP) IBbeta with GPIX-a genetic cause of Bernard-Soulier syndrome. (Kenny D, Morateck PA, Gill JC, Montgomery RR) Blood 1999 May 01;93(9):2968-75 61 Citations |
| 1 | Intracellular expression of the ADP-ribosyltransferase domain of Pseudomonas exoenzyme S is cytotoxic to eukaryotic cells. (Pederson KJ, Barbieri JT) Mol Microbiol 1998 Nov;30(4):751-9 60 Citations |
| 1 | Ras enhances Myc protein stability. (Sears R, Leone G, DeGregori J, Nevins JR) Mol Cell 1999 Feb;3(2):169-79 331 Citations |
| 1 | Kidney is the only source of human plasma renin in 45-kb human renin transgenic mice. (Yan Y, Chen R, Pitarresi T, Sigmund CD, Gross KW, Sealey JE, Laragh JH, Catanzaro DF) Circ Res 1998 Dec 14-28;83(12):1279-88 25 Citations |
| 1 | Functionally active catalytic domain is essential for guanylyl cyclase-linked receptor mediated inhibition of human aldosterone synthesis. (Olson LJ, Ho BY, Cashdollar LW, Drewett JG) Mol Pharmacol 1998 Nov;54(5):761-9 10 Citations |
| 2 | An antibody from a patient with ranitidine-induced thrombocytopenia recognizes a site on glycoprotein IX that is a favored target for drug-induced antibodies. (Gentilini G, Curtis BR, Aster RH) Blood 1998 Oct 01;92(7):2359-65 48 Citations |
| 1 | The two mannose 6-phosphate binding sites of the insulin-like growth factor-II/mannose 6-phosphate receptor display different ligand binding properties. (Marron-Terada PG, Brzycki-Wessell MA, Dahms NM) J Biol Chem 1998 Aug 28;273(35):22358-66 27 Citations |
| 1 | Mutations in Drosophila enabled and rescue by human vasodilator-stimulated phosphoprotein (VASP) indicate important functional roles for Ena/VASP homology domain 1 (EVH1) and EVH2 domains. (Ahern-Djamali SM, Comer AR, Bachmann C, Kastenmeier AS, Reddy SK, Beckerle MC, Walter U, Hoffmann FM) Mol Biol Cell 1998 Aug;9(8):2157-71 87 Citations |
| 1 | The neuropeptide Y/peptide YY Y1 receptor is coupled to MAP kinase via PKC and Ras in CHO cells. (Mannon PJ, Raymond JR) Biochem Biophys Res Commun 1998 May 08;246(1):91-4 29 Citations |
| 1 | Characterization of the chimeric retinoic acid receptor RARalpha/VDR. (Pemrick SM, Abarzúa P, Kratzeisen C, Marks MS, Medin JA, Ozato K, Grippo JF) Leukemia 1998 Apr;12(4):554-62 5 Citations |
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| 1 | Retinoid X receptor and peroxisome proliferator-activated receptor activate an estrogen responsive gene independent of the estrogen receptor. (Nuñez SB, Medin JA, Braissant O, Kemp L, Wahli W, Ozato K, Segars JH) Mol Cell Endocrinol 1997 Mar 14;127(1):27-40 88 Citations |
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| 1 | Distinct signaling pathways mediate induction of c-fos by PGE2 in glomerular mesangial cells. (Simonson MS, Herman WH, Dunn MJ) Adv Exp Med Biol 1997;400A:279-86 2 Citations |
| 1 | Somatic gene transfer approaches to manipulate neural networks. (Federoff HJ, Brooks A, Muhkerjee B, Corden T) J Neurosci Methods 1997 Jan;71(1):133-42 11 Citations |
| 1 | Engagement of the Lewis X antigen (CD15) results in monocyte activation. (Lo SK, Golenbock DT, Sass PM, Maskati A, Xu H, Silverstein RL) Blood 1997 Jan 01;89(1):307-14 33 Citations |
| 1 | Functional analysis of E2F transcription factor. (Nevins JR, DeGregori J, Jakoi L, Leone G) Methods Enzymol 1997;283:205-19 71 Citations |
| 1 | The mouse mammary tumor virus env gene is the source of a CD8+ T-cell-stimulating peptide presented by a major histocompatibility complex class I molecule in a murine thymoma. (Malarkannan S, Serwold T, Nguyen V, Sherman LA, Shastri N) Proc Natl Acad Sci U S A 1996 Nov 26;93(24):13991-6 22 Citations |
| 1 | PCR-based gene targeting of the inducible nitric oxide synthase (NOS2) locus in murine ES cells, a new and more cost-effective approach. (Randolph DA, Verbsky JW, Yang L, Fang Y, Hakem R, Fields LE) Transgenic Res 1996 Nov;5(6):413-20 6 Citations |
| 1 | Ras-dependent activation of fibroblast mitogen-activated protein kinase by 5-HT1A receptor via a G protein beta gamma-subunit-initiated pathway. (Garnovskaya MN, van Biesen T, Hawe B, Casañas Ramos S, Lefkowitz RJ, Raymond JR) Biochemistry 1996 Oct 29;35(43):13716-22 95 Citations |
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| 1 | Correction in trans for Fabry disease: expression, secretion and uptake of alpha-galactosidase A in patient-derived cells driven by a high-titer recombinant retroviral vector. (Medin JA, Tudor M, Simovitch R, Quirk JM, Jacobson S, Murray GJ, Brady RO) Proc Natl Acad Sci U S A 1996 Jul 23;93(15):7917-22 58 Citations |
| 1 | Alpha-myosin heavy chain gene regulation: delineation and characterization of the cardiac muscle-specific enhancer and muscle-specific promoter. (Molkentin JD, Jobe SM, Markham BE) J Mol Cell Cardiol 1996 Jun;28(6):1211-25 52 Citations |
| 1 | Inconstant association between 27-kDa heat-shock protein (Hsp27) content and doxorubicin resistance in human colon cancer cells. The doxorubicin-protecting effect of Hsp27. (Garrido C, Mehlen P, Fromentin A, Hammann A, Assem M, Arrigo AP, Chauffert B) Eur J Biochem 1996 May 01;237(3):653-9 77 Citations |
| 1 | Glycosylation structure and enzyme activity of lecithin:cholesterol acyltransferase from human plasma, HepG2 cells, and baculoviral and Chinese hamster ovary cell expression systems. (Miller KR, Wang J, Sorci-Thomas M, Anderson RA, Parks JS) J Lipid Res 1996 Mar;37(3):551-61 26 Citations |
| 1 | A bicistronic therapeutic retroviral vector enables sorting of transduced CD34+ cells and corrects the enzyme deficiency in cells from Gaucher patients. (Medin JA, Migita M, Pawliuk R, Jacobson S, Amiri M, Kluepfel-Stahl S, Brady RO, Humphries RK, Karlsson S) Blood 1996 Mar 01;87(5):1754-62 34 Citations |
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| 1 | Two strong 5' splice sites and competing, suboptimal 3' splice sites involved in alternative splicing of human immunodeficiency virus type 1 RNA. (O'Reilly MM, McNally MT, Beemon KL) Virology 1995 Nov 10;213(2):373-85 |
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| 1 | Activation of human endothelial cells by viable or heat-killed gram-negative bacteria requires soluble CD14. (Noel RF Jr, Sato TT, Mendez C, Johnson MC, Pohlman TH) Infect Immun 1995 Oct;63(10):4046-53 35 Citations |
| 1 | E1A gene expression induces susceptibility to killing by NK cells following immortalization but not adenovirus infection of human cells. (Routes JM, Cook JL) Virology 1995 Jul 10;210(2):421-8 |
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| 1 | Regulation of allergic contact sensitivity in mice: soluble alpha beta T cell receptors, derived via cDNA transfection and enzymatic cleavage from the surface of T cells, protect contact sensitivity effector T cells from active T cell suppression. (Paliwal V, Ptak W, Askenase PW) Int Arch Allergy Immunol 1995 May-Jun;107(1-3):365 1 Citation |
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