| 1 | Genetic engineering of megakaryocytes from blood progenitor cells using messenger RNA lipid nanoparticles. (Leung J, Primbetova A, Strong C, Hay BN, Hsu HH, Hagner A, Foster LJ, Devine D, Cullis PR, Zandstra PW, Kastrup CJ) J Thromb Haemost 2025 Jan;23(1):306-313 |
| 1 | Genetic engineering of transfusable platelets with mRNA-lipid nanoparticles is compatible with blood banking practices. (Strong C, Leung J, Kang E, Badior KE, Robertson M, Pereyra N, Rowe EM, Wietrzny A, Ma B, Noronha Z, Arnold D, Ciufolini MA, Devine DV, Jan E, Cullis PR, Kastrup CJ) Blood 2024 Nov 21;144(21):2223-2236 3 Citations |
| 1 | Emerging gene therapies for enhancing the hemostatic potential of platelets. (Leung J, Cau MF, Kastrup CJ) Transfusion 2021 Jul;61 Suppl 1:S275-S285 3 Citations |
| 7 | Peritoneal Spread of Ovarian Cancer Harbors Therapeutic Vulnerabilities Regulated by FOXM1 and EGFR/ERBB2 Signaling. (Parashar D, Nair B, Geethadevi A, George J, Nair A, Tsaih SW, Kadamberi IP, Gopinadhan Nair GK, Lu Y, Ramchandran R, Uyar DS, Rader JS, Ram PT, Mills GB, Pradeep S, Chaluvally-Raghavan P) Cancer Res 2020 Dec 15;80(24):5554-5568 32 Citations |
| 1 | Potential of avian and mammalian species A rotaviruses to reassort as explored by plasmid only-based reverse genetics. (Patzina-Mehling C, Falkenhagen A, Trojnar E, Gadicherla AK, Johne R) Virus Res 2020 Sep;286:198027 17 Citations |
| 4 | AMP-Kinase Dysfunction Alters Notch Ligands to Impair Angiogenesis in Neonatal Pulmonary Hypertension. (Rana U, Callan E, Entringer B, Michalkiewicz T, Joshi A, Parchur AK, Teng RJ, Konduri GG) Am J Respir Cell Mol Biol 2020 Jun;62(6):719-731 25 Citations |
| 1 | Proteasome activation by insulin-like growth factor-1/nuclear factor erythroid 2-related factor 2 signaling promotes exercise-induced neurogenesis. (Niu X, Zhao Y, Yang N, Zhao X, Zhang W, Bai X, Li A, Yang W, Lu L) Stem Cells 2020 Feb;38(2):246-260 19 Citations |
| 1 | pHluorin-BACE1-mCherry Acts as a Reporter for the Intracellular Distribution of Active BACE1 In Vitro and In Vivo. (Zhao L, Zhao Y, Tang FL, Xiong L, Su C, Mei L, Zhu XJ, Xiong WC) Cells 2019 May 17;8(5) 11 Citations |
| 1 | Characterization of a KLK2-FGFR2 fusion gene in two cases of metastatic prostate cancer. (Krook MA, Barker H, Chen HZ, Reeser JW, Wing MR, Martin D, Smith AM, Dao T, Bonneville R, Samorodnitsky E, Miya J, Freud AG, Monk JP, Clinton SK, Roychowdhury S) Prostate Cancer Prostatic Dis 2019 Dec;22(4):624-632 7 Citations |
| 1 | Delivery of mRNA to platelets using lipid nanoparticles. (Novakowski S, Jiang K, Prakash G, Kastrup C) Sci Rep 2019 Jan 24;9(1):552 28 Citations |
| 2 | Methods for imaging mammalian mitochondrial morphology: A prospective on MitoGraph. (Harwig MC, Viana MP, Egner JM, Harwig JJ, Widlansky ME, Rafelski SM, Hill RB) Anal Biochem 2018 Jul 01;552:81-99 68 Citations |
| 1 | Intravenous Administration of a MTMR2-Encoding AAV Vector Ameliorates the Phenotype of Myotubular Myopathy in Mice. (Danièle N, Moal C, Julien L, Marinello M, Jamet T, Martin S, Vignaud A, Lawlor MW, Buj-Bello A) J Neuropathol Exp Neurol 2018 Apr 01;77(4):282-295 18 Citations |
| 1 | α1-Adrenergic Receptors Function Within Hetero-Oligomeric Complexes With Atypical Chemokine Receptor 3 and Chemokine (C-X-C motif) Receptor 4 in Vascular Smooth Muscle Cells. (Albee LJ, Eby JM, Tripathi A, LaPorte HM, Gao X, Volkman BF, Gaponenko V, Majetschak M) J Am Heart Assoc 2017 Aug 17;6(8) 29 Citations |
| 2 | Cardiotonic Steroids Stimulate Macrophage Inflammatory Responses Through a Pathway Involving CD36, TLR4, and Na/K-ATPase. (Chen Y, Huang W, Yang M, Xin G, Cui W, Xie Z, Silverstein RL) Arterioscler Thromb Vasc Biol 2017 Aug;37(8):1462-1469 28 Citations |
| 1 | Exosome-Derived miR-25-3p and miR-92a-3p Stimulate Liposarcoma Progression. (Casadei L, Calore F, Creighton CJ, Guescini M, Batte K, Iwenofu OH, Zewdu A, Braggio DA, Bill KL, Fadda P, Lovat F, Lopez G, Gasparini P, Chen JL, Kladney RD, Leone G, Lev D, Croce CM, Pollock RE) Cancer Res 2017 Jul 15;77(14):3846-3856 160 Citations |
| 1 | Clinical and laboratory phenotype variability in type 2M von Willebrand disease. (Doruelo AL, Haberichter SL, Christopherson PA, Boggio LN, Gupta S, Lentz SR, Shapiro AD, Montgomery RR, Flood VH) J Thromb Haemost 2017 Aug;15(8):1559-1566 19 Citations |
| 1 | The application of CRISPR technology to high content screening in primary neurons. (Callif BL, Maunze B, Krueger NL, Simpson MT, Blackmore MG) Mol Cell Neurosci 2017 Apr;80:170-179 11 Citations |
| 2 | Sucrose Nonfermenting-Related Kinase Enzyme-Mediated Rho-Associated Kinase Signaling is Responsible for Cardiac Function. (Cossette SM, Bhute VJ, Bao X, Harmann LM, Horswill MA, Sinha I, Gastonguay A, Pooya S, Bordas M, Kumar SN, Mirza SP, Palecek SP, Strande JL, Ramchandran R) Circ Cardiovasc Genet 2016 Dec;9(6):474-486 14 Citations |
| 1 | Improving vascular maturation using noncoding RNAs increases antitumor effect of chemotherapy. (Mangala LS, Wang H, Jiang D, Wu SY, Somasunderam A, Volk DE, Lokesh GLR, Li X, Pradeep S, Yang X, Haemmerle M, Rodriguez-Aguayo C, Nagaraja AS, Rupaimoole R, Bayraktar E, Bayraktar R, Li L, Tanaka T, Hu W, Ivan C, Gharpure KM, McGuire MH, Thiviyanathan V, Zhang X, Maiti SN, Bulayeva N, Choi HJ, Dorniak PL, Cooper LJ, Rosenblatt KP, Lopez-Berestein G, Gorenstein DG, Sood AK) JCI Insight 2016 Oct 20;1(17):e87754 13 Citations |
| 1 | Mitochondrial Protein Interaction Mapping Identifies Regulators of Respiratory Chain Function. (Floyd BJ, Wilkerson EM, Veling MT, Minogue CE, Xia C, Beebe ET, Wrobel RL, Cho H, Kremer LS, Alston CL, Gromek KA, Dolan BK, Ulbrich A, Stefely JA, Bohl SL, Werner KM, Jochem A, Westphall MS, Rensvold JW, Taylor RW, Prokisch H, Kim JP, Coon JJ, Pagliarini DJ) Mol Cell 2016 Aug 18;63(4):621-632 217 Citations |
| 1 | Monosialoganglioside-Containing Nanoliposomes Restore Endothelial Function Impaired by AL Amyloidosis Light Chain Proteins. (Franco DA, Truran S, Weissig V, Guzman-Villanueva D, Karamanova N, Senapati S, Burciu C, Ramirez-Alvarado M, Blancas-Mejia LM, Lindsay S, Hari P, Migrino RQ) J Am Heart Assoc 2016 Jun 13;5(6) 10 Citations |
| 2 | Antiendothelial αvβ3 Antibodies Are a Major Cause of Intracranial Bleeding in Fetal/Neonatal Alloimmune Thrombocytopenia. (Santoso S, Wihadmadyatami H, Bakchoul T, Werth S, Al-Fakhri N, Bein G, Kiefel V, Zhu J, Newman PJ, Bayat B, Sachs UJ) Arterioscler Thromb Vasc Biol 2016 Aug;36(8):1517-24 81 Citations |
| 1 | LPA/PKD-1-FoxO1 Signaling Axis Mediates Endothelial Cell CD36 Transcriptional Repression and Proangiogenic and Proarteriogenic Reprogramming. (Ren B, Best B, Ramakrishnan DP, Walcott BP, Storz P, Silverstein RL) Arterioscler Thromb Vasc Biol 2016 Jun;36(6):1197-208 45 Citations |
| 1 | Estrogen Receptor α Is Required for Maintaining Baseline Renin Expression. (Lu KT, Keen HL, Weatherford ET, Sequeira-Lopez ML, Gomez RA, Sigmund CD) Hypertension 2016 May;67(5):992-9 20 Citations |
| 2 | Ndufc2 Gene Inhibition Is Associated With Mitochondrial Dysfunction and Increased Stroke Susceptibility in an Animal Model of Complex Human Disease. (Rubattu S, Di Castro S, Schulz H, Geurts AM, Cotugno M, Bianchi F, Maatz H, Hummel O, Falak S, Stanzione R, Marchitti S, Scarpino S, Giusti B, Kura A, Gensini GF, Peyvandi F, Mannucci PM, Rasura M, Sciarretta S, Dwinell MR, Hubner N, Volpe M) J Am Heart Assoc 2016 Feb 17;5(2) 46 Citations |
| 1 | Variants in TRIM22 That Affect NOD2 Signaling Are Associated With Very-Early-Onset Inflammatory Bowel Disease. (Li Q, Lee CH, Peters LA, Mastropaolo LA, Thoeni C, Elkadri A, Schwerd T, Zhu J, Zhang B, Zhao Y, Hao K, Dinarzo A, Hoffman G, Kidd BA, Murchie R, Al Adham Z, Guo C, Kotlarz D, Cutz E, Walters TD, Shouval DS, Curran M, Dobrin R, Brodmerkel C, Snapper SB, Klein C, Brumell JH, Hu M, Nanan R, Snanter-Nanan B, Wong M, Le Deist F, Haddad E, Roifman CM, Deslandres C, Griffiths AM, Gaskin KJ, Uhlig HH, Schadt EE, Muise AM) Gastroenterology 2016 May;150(5):1196-1207 93 Citations |
| 2 | Extracellular Vesicles Activate a CD36-Dependent Signaling Pathway to Inhibit Microvascular Endothelial Cell Migration and Tube Formation. (Ramakrishnan DP, Hajj-Ali RA, Chen Y, Silverstein RL) Arterioscler Thromb Vasc Biol 2016 Mar;36(3):534-44 53 Citations |
| 1 | A bispecific protein rG7S-MICA recruits natural killer cells and enhances NKG2D-mediated immunosurveillance against hepatocellular carcinoma. (Wang T, Sun F, Xie W, Tang M, He H, Jia X, Tian X, Wang M, Zhang J) Cancer Lett 2016 Mar 28;372(2):166-78 46 Citations |
| 2 | Structural basis for PECAM-1 homophilic binding. (Paddock C, Zhou D, Lertkiatmongkol P, Newman PJ, Zhu J) Blood 2016 Feb 25;127(8):1052-61 47 Citations |
| 1 | Valve Endothelial Cell-Derived Tgfβ1 Signaling Promotes Nuclear Localization of Sox9 in Interstitial Cells Associated With Attenuated Calcification. (Huk DJ, Austin BF, Horne TE, Hinton RB, Ray WC, Heistad DD, Lincoln J) Arterioscler Thromb Vasc Biol 2016 Feb;36(2):328-38 57 Citations |
| 1 | Neuronostatin acts via GPR107 to increase cAMP-independent PKA phosphorylation and proglucagon mRNA accumulation in pancreatic α-cells. (Elrick MM, Samson WK, Corbett JA, Salvatori AS, Stein LM, Kolar GR, Naatz A, Yosten GL) Am J Physiol Regul Integr Comp Physiol 2016 Jan 15;310(2):R143-55 38 Citations |
| 1 | Genetic Variants That Predispose to DNA Double-Strand Breaks in Lymphocytes From a Subset of Patients With Familial Colorectal Carcinomas. (Arora S, Yan H, Cho I, Fan HY, Luo B, Gai X, Bodian DL, Vockley JG, Zhou Y, Handorf EA, Egleston BL, Andrake MD, Nicolas E, Serebriiskii IG, Yen TJ, Hall MJ, Golemis EA, Enders GH) Gastroenterology 2015 Dec;149(7):1872-1883.e9 29 Citations |
| 1 | Intravitreal delivery of a novel AAV vector targets ON bipolar cells and restores visual function in a mouse model of complete congenital stationary night blindness. (Scalabrino ML, Boye SL, Fransen KM, Noel JM, Dyka FM, Min SH, Ruan Q, De Leeuw CN, Simpson EM, Gregg RG, McCall MA, Peachey NS, Boye SE) Hum Mol Genet 2015 Nov 01;24(21):6229-39 60 Citations |
| 1 | The tumor suppressor HHEX inhibits axon growth when prematurely expressed in developing central nervous system neurons. (Simpson MT, Venkatesh I, Callif BL, Thiel LK, Coley DM, Winsor KN, Wang Z, Kramer AA, Lerch JK, Blackmore MG) Mol Cell Neurosci 2015 Sep;68:272-83 18 Citations |
| 2 | Acceleration of Lung Regeneration by Platelet-Rich Plasma Extract through the Low-Density Lipoprotein Receptor-Related Protein 5-Tie2 Pathway. (Mammoto T, Chen Z, Jiang A, Jiang E, Ingber DE, Mammoto A) Am J Respir Cell Mol Biol 2016 Jan;54(1):103-13 25 Citations |
| 1 | NPM-ALK mediates phosphorylation of MSH2 at tyrosine 238, creating a functional deficiency in MSH2 and the loss of mismatch repair. (Bone KM, Wang P, Wu F, Wu C, Li L, Bacani JT, Andrew SE, Lai R) Blood Cancer J 2015 May 15;5(5):e311 10 Citations |
| 1 | MicroRNA-135b Regulates Leucine Zipper Tumor Suppressor 1 in Cutaneous Squamous Cell Carcinoma. (Olasz EB, Seline LN, Schock AM, Duncan NE, Lopez A, Lazar J, Flister MJ, Lu Y, Liu P, Sokumbi O, Harwood CA, Proby CM, Neuburg M, Lazarova Z) PLoS One 2015;10(5):e0125412 31 Citations |
| 2 | Functional Characterization of Nupr1L, A Novel p53-Regulated Isoform of the High-Mobility Group (HMG)-Related Protumoral Protein Nupr1. (Lopez MB, Garcia MN, Grasso D, Bintz J, Molejon MI, Velez G, Lomberk G, Neira JL, Urrutia R, Iovanna J) J Cell Physiol 2015 Dec;230(12):2936-50 13 Citations |
| 1 | XPO1/CRM1 Inhibition Causes Antitumor Effects by Mitochondrial Accumulation of eIF5A. (Miyake T, Pradeep S, Wu SY, Rupaimoole R, Zand B, Wen Y, Gharpure KM, Nagaraja AS, Hu W, Cho MS, Dalton HJ, Previs RA, Taylor ML, Hisamatsu T, Kang Y, Liu T, Shacham S, McCauley D, Hawke DH, Wiktorowicz JE, Coleman RL, Sood AK) Clin Cancer Res 2015 Jul 15;21(14):3286-97 39 Citations |
| 1 | Rac1/Pak1/p38/MMP-2 Axis Regulates Angiogenesis in Ovarian Cancer. (Gonzalez-Villasana V, Fuentes-Mattei E, Ivan C, Dalton HJ, Rodriguez-Aguayo C, Fernandez-de Thomas RJ, Aslan B, Del C Monroig P, Velazquez-Torres G, Previs RA, Pradeep S, Kahraman N, Wang H, Kanlikilicer P, Ozpolat B, Calin G, Sood AK, Lopez-Berestein G) Clin Cancer Res 2015 May 01;21(9):2127-37 68 Citations |
| 1 | Copackaging of multiple adeno-associated viral vectors in a single production step. (Doerfler PA, Byrne BJ, Clément N) Hum Gene Ther Methods 2014 Oct;25(5):269-76 3 Citations |
| 1 | Epidermal growth factor-induced proliferation of collecting duct cells from Oak Ridge polycystic kidney mice involves activation of Na+/H+ exchanger. (Coaxum SD, Blanton MG, Joyner A, Akter T, Bell PD, Luttrell LM, Raymond JR Sr, Lee MH, Blichmann PA, Garnovskaya MN, Saigusa T) Am J Physiol Cell Physiol 2014 Sep 15;307(6):C554-60 10 Citations |
| 2 | Hematogenous metastasis of ovarian cancer: rethinking mode of spread. (Pradeep S, Kim SW, Wu SY, Nishimura M, Chaluvally-Raghavan P, Miyake T, Pecot CV, Kim SJ, Choi HJ, Bischoff FZ, Mayer JA, Huang L, Nick AM, Hall CS, Rodriguez-Aguayo C, Zand B, Dalton HJ, Arumugam T, Lee HJ, Han HD, Cho MS, Rupaimoole R, Mangala LS, Sehgal V, Oh SC, Liu J, Lee JS, Coleman RL, Ram P, Lopez-Berestein G, Fidler IJ, Sood AK) Cancer Cell 2014 Jul 14;26(1):77-91 262 Citations |
| 1 | Post-translational regulation of COX2 activity by FYN in prostate cancer cells. (Alexanian A, Miller B, Chesnik M, Mirza S, Sorokin A) Oncotarget 2014 Jun 30;5(12):4232-43 22 Citations |
| 3 | Identification of a ternary protein-complex as a therapeutic target for K-Ras-dependent colon cancer. (Qi X, Xie C, Hou S, Li G, Yin N, Dong L, Lepp A, Chesnik MA, Mirza SP, Szabo A, Tsai S, Basir Z, Wu S, Chen G) Oncotarget 2014 Jun 30;5(12):4269-82 19 Citations |
| 2 | Differential coupling of KLF10 to Sin3-HDAC and PCAF regulates the inducibility of the FOXP3 gene. (Xiong Y, Svingen PA, Sarmento OO, Smyrk TC, Dave M, Khanna S, Lomberk GA, Urrutia RA, Faubion WA Jr) Am J Physiol Regul Integr Comp Physiol 2014 Sep 15;307(6):R608-20 24 Citations |
| 1 | Variants in nicotinamide adenine dinucleotide phosphate oxidase complex components determine susceptibility to very early onset inflammatory bowel disease. (Dhillon SS, Fattouh R, Elkadri A, Xu W, Murchie R, Walters T, Guo C, Mack D, Huynh HQ, Baksh S, Silverberg MS, Griffiths AM, Snapper SB, Brumell JH, Muise AM) Gastroenterology 2014 Sep;147(3):680-689.e2 108 Citations |
| 4 | Rap1b in smooth muscle and endothelium is required for maintenance of vascular tone and normal blood pressure. (Lakshmikanthan S, Zieba BJ, Ge ZD, Momotani K, Zheng X, Lund H, Artamonov MV, Maas JE, Szabo A, Zhang DX, Auchampach JA, Mattson DL, Somlyo AV, Chrzanowska-Wodnicka M) Arterioscler Thromb Vasc Biol 2014 Jul;34(7):1486-94 47 Citations |
| 1 | Autocrine effects of tumor-derived complement. (Cho MS, Vasquez HG, Rupaimoole R, Pradeep S, Wu S, Zand B, Han HD, Rodriguez-Aguayo C, Bottsford-Miller J, Huang J, Miyake T, Choi HJ, Dalton HJ, Ivan C, Baggerly K, Lopez-Berestein G, Sood AK, Afshar-Kharghan V) Cell Rep 2014 Mar 27;6(6):1085-1095 173 Citations |
| 1 | Possible role of arginase-1 in concomitant tumor immunity. (Korrer MJ, Zhang Y, Routes JM) PLoS One 2014;9(3):e91370 13 Citations |
| 2 | CXCL12 chemokine expression suppresses human pancreatic cancer growth and metastasis. (Roy I, Zimmerman NP, Mackinnon AC, Tsai S, Evans DB, Dwinell MB) PLoS One 2014;9(3):e90400 78 Citations |
| 1 | HO-3867, a safe STAT3 inhibitor, is selectively cytotoxic to ovarian cancer. (Rath KS, Naidu SK, Lata P, Bid HK, Rivera BK, McCann GA, Tierney BJ, Elnaggar AC, Bravo V, Leone G, Houghton P, Hideg K, Kuppusamy P, Cohn DE, Selvendiran K) Cancer Res 2014 Apr 15;74(8):2316-27 77 Citations |
| 3 | Nogo-B receptor modulates angiogenesis response of pulmonary artery endothelial cells through eNOS coupling. (Teng RJ, Rana U, Afolayan AJ, Zhao B, Miao QR, Konduri GG) Am J Respir Cell Mol Biol 2014 Aug;51(2):169-77 20 Citations |
| 1 | Mechanotransduction of fluid stresses governs 3D cell migration. (Polacheck WJ, German AE, Mammoto A, Ingber DE, Kamm RD) Proc Natl Acad Sci U S A 2014 Feb 18;111(7):2447-52 216 Citations |
| 1 | Dickkopf-1, the Wnt antagonist, is induced by acidic pH and mediates epithelial cellular senescence in human reflux esophagitis. (Lyros O, Rafiee P, Nie L, Medda R, Jovanovic N, Schmidt J, Mackinnon A, Venu N, Shaker R) Am J Physiol Gastrointest Liver Physiol 2014 Apr 01;306(7):G557-74 27 Citations |
| 1 | Mutations in tetratricopeptide repeat domain 7A result in a severe form of very early onset inflammatory bowel disease. (Avitzur Y, Guo C, Mastropaolo LA, Bahrami E, Chen H, Zhao Z, Elkadri A, Dhillon S, Murchie R, Fattouh R, Huynh H, Walker JL, Wales PW, Cutz E, Kakuta Y, Dudley J, Kammermeier J, Powrie F, Shah N, Walz C, Nathrath M, Kotlarz D, Puchaka J, Krieger JR, Racek T, Kirchner T, Walters TD, Brumell JH, Griffiths AM, Rezaei N, Rashtian P, Najafi M, Monajemzadeh M, Pelsue S, McGovern DP, Uhlig HH, Schadt E, Klein C, Snapper SB, Muise AM) Gastroenterology 2014 Apr;146(4):1028-39 176 Citations |
| 1 | Circadian rhythm of contrast sensitivity is regulated by a dopamine-neuronal PAS-domain protein 2-adenylyl cyclase 1 signaling pathway in retinal ganglion cells. (Hwang CK, Chaurasia SS, Jackson CR, Chan GC, Storm DR, Iuvone PM) J Neurosci 2013 Sep 18;33(38):14989-97 60 Citations |
| 1 | Activation of MAPK pathways due to DUSP4 loss promotes cancer stem cell-like phenotypes in basal-like breast cancer. (Balko JM, Schwarz LJ, Bhola NE, Kurupi R, Owens P, Miller TW, Gómez H, Cook RS, Arteaga CL) Cancer Res 2013 Oct 15;73(20):6346-58 131 Citations |
| 1 | Nicotine potentiates proatherogenic effects of oxLDL by stimulating and upregulating macrophage CD36 signaling. (Zhou MS, Chadipiralla K, Mendez AJ, Jaimes EA, Silverstein RL, Webster K, Raij L) Am J Physiol Heart Circ Physiol 2013 Aug 15;305(4):H563-74 58 Citations |
| 1 | Statins exert the pleiotropic effects through small GTP-binding protein dissociation stimulator upregulation with a resultant Rac1 degradation. (Tanaka S, Fukumoto Y, Nochioka K, Minami T, Kudo S, Shiba N, Takai Y, Williams CL, Liao JK, Shimokawa H) Arterioscler Thromb Vasc Biol 2013 Jul;33(7):1591-600 78 Citations |
| 1 | In vivo gene delivery with L-tyrosine polyphosphate nanoparticles. (Ditto AJ, Reho JJ, Shah KN, Smolen JA, Holda JH, Ramirez RJ, Yun YH) Mol Pharm 2013 May 06;10(5):1836-44 8 Citations |
| 2 | Adenosine A1 receptors heterodimerize with β1- and β2-adrenergic receptors creating novel receptor complexes with altered G protein coupling and signaling. (Chandrasekera PC, Wan TC, Gizewski ET, Auchampach JA, Lasley RD) Cell Signal 2013 Apr;25(4):736-42 38 Citations |
| 1 | Neutrophil proteinase 3 acts on protease-activated receptor-2 to enhance vascular endothelial cell barrier function. (Kuckleburg CJ, Newman PJ) Arterioscler Thromb Vasc Biol 2013 Feb;33(2):275-84 34 Citations |
| 1 | Increased dietary intake of vitamin A promotes aortic valve calcification in vivo. (Huk DJ, Hammond HL, Kegechika H, Lincoln J) Arterioscler Thromb Vasc Biol 2013 Feb;33(2):285-93 30 Citations |
| 1 | Glycosylation-independent lysosomal targeting of acid α-glucosidase enhances muscle glycogen clearance in pompe mice. (Maga JA, Zhou J, Kambampati R, Peng S, Wang X, Bohnsack RN, Thomm A, Golata S, Tom P, Dahms NM, Byrne BJ, LeBowitz JH) J Biol Chem 2013 Jan 18;288(3):1428-38 91 Citations |
| 1 | Mechanism of loss of Kv11.1 K+ current in mutant T421M-Kv11.1-expressing rat ventricular myocytes: interaction of trafficking and gating. (Balijepalli SY, Lim E, Concannon SP, Chew CL, Holzem KE, Tester DJ, Ackerman MJ, Delisle BP, Balijepalli RC, January CT) Circulation 2012 Dec 11;126(24):2809-18 13 Citations |
| 2 | Cullin-3 regulates vascular smooth muscle function and arterial blood pressure via PPARγ and RhoA/Rho-kinase. (Pelham CJ, Ketsawatsomkron P, Groh S, Grobe JL, de Lange WJ, Ibeawuchi SR, Keen HL, Weatherford ET, Faraci FM, Sigmund CD) Cell Metab 2012 Oct 03;16(4):462-72 88 Citations |
| 1 | Comparison of cell expression formats for the characterization of GABA(A) channels using a microfluidic patch clamp system. (Chen Q, Yim PD, Yuan N, Johnson J, Cook JM, Smith S, Ionescu-Zanetti C, Wang ZJ, Arnold LA, Emala CW) Assay Drug Dev Technol 2012 Aug;10(4):325-35 7 Citations |
| 2 | Intersection of mechanisms of type 2A VWD through defects in VWF multimerization, secretion, ADAMTS-13 susceptibility, and regulated storage. (Jacobi PM, Gill JC, Flood VH, Jakab DA, Friedman KD, Haberichter SL) Blood 2012 May 10;119(19):4543-53 52 Citations |
| 1 | Bystander killing of malignant cells via the delivery of engineered thymidine-active deoxycytidine kinase for suicide gene therapy of cancer. (Neschadim A, Wang JC, Lavie A, Medin JA) Cancer Gene Ther 2012 May;19(5):320-7 20 Citations |
| 1 | PDE4 regulates tissue plasminogen activator expression of human brain microvascular endothelial cells. (Yang F, Liu S, Yu C, Wang SJ, Paganini-Hill A, Fisher MJ) Thromb Res 2012 Jun;129(6):750-3 17 Citations |
| 1 | CD36 ectodomain phosphorylation blocks thrombospondin-1 binding: structure-function relationships and regulation by protein kinase C. (Chu LY, Silverstein RL) Arterioscler Thromb Vasc Biol 2012 Mar;32(3):760-7 33 Citations |
| 2 | A newly identified complex of spinophilin and the tyrosine phosphatase, SHP-1, modulates platelet activation by regulating G protein-dependent signaling. (Ma P, Cierniewska A, Signarvic R, Cieslak M, Kong H, Sinnamon AJ, Neubig RR, Newman DK, Stalker TJ, Brass LF) Blood 2012 Feb 23;119(8):1935-45 53 Citations |
| 1 | Functional analysis of the Hsf4(lop11) allele responsible for cataracts in lop11 mice. (Liang L, Liegel R, Endres B, Ronchetti A, Chang B, Sidjanin DJ) Mol Vis 2011;17:3062-71 6 Citations |
| 1 | AAV-mediated gene transfer of human X-linked inhibitor of apoptosis protects against oxidative cell death in human RPE cells. (Shan H, Ji D, Barnard AR, Lipinski DM, You Q, Lee EJ, Kamalden TA, Sun X, MacLaren RE) Invest Ophthalmol Vis Sci 2011 Dec 20;52(13):9591-7 17 Citations |
| 1 | R1507, an anti-insulin-like growth factor-1 receptor (IGF-1R) antibody, and EWS/FLI-1 siRNA in Ewing's sarcoma: convergence at the IGF/IGFR/Akt axis. (Huang HJ, Angelo LS, Rodon J, Sun M, Kuenkele KP, Parsons HA, Trent JC, Kurzrock R) PLoS One 2011;6(10):e26060 37 Citations |
| 1 | PITX2 is involved in stress response in cultured human trabecular meshwork cells through regulation of SLC13A3. (Strungaru MH, Footz T, Liu Y, Berry FB, Belleau P, Semina EV, Raymond V, Walter MA) Invest Ophthalmol Vis Sci 2011 Sep 29;52(10):7625-33 25 Citations |
| 1 | Defining the nature of human pluripotent stem cell progeny. (Patterson M, Chan DN, Ha I, Case D, Cui Y, Van Handel B, Mikkola HK, Lowry WE) Cell Res 2012 Jan;22(1):178-93 113 Citations |
| 1 | Melatonin synthesis in retina: cAMP-dependent transcriptional regulation of chicken arylalkylamine N-acetyltransferase by a CRE-like sequence and a TTATT repeat motif in the proximal promoter. (Haque R, Chong NW, Ali F, Chaurasia SS, Sengupta T, Chun E, Howell JC, Klein DC, Iuvone PM) J Neurochem 2011 Oct;119(1):6-17 22 Citations |
| 1 | Constitutive androstane receptor activation decreases plasma apolipoprotein B-containing lipoproteins and atherosclerosis in low-density lipoprotein receptor-deficient mice. (Sberna AL, Assem M, Xiao R, Ayers S, Gautier T, Guiu B, Deckert V, Chevriaux A, Grober J, Le Guern N, Pais de Barros JP, Moore DD, Lagrost L, Masson D) Arterioscler Thromb Vasc Biol 2011 Oct;31(10):2232-9 32 Citations |
| 1 | Using tandem mass spectrometry in targeted mode to identify activators of class IA PI3K in cancer. (Yang X, Turke AB, Qi J, Song Y, Rexer BN, Miller TW, Jänne PA, Arteaga CL, Cantley LC, Engelman JA, Asara JM) Cancer Res 2011 Sep 15;71(18):5965-75 15 Citations |
| 1 | NMDA receptor modulation by the neuropeptide apelin: implications for excitotoxic injury. (Cook DR, Gleichman AJ, Cross SA, Doshi S, Ho W, Jordan-Sciutto KL, Lynch DR, Kolson DL) J Neurochem 2011 Sep;118(6):1113-23 62 Citations |
| 1 | Transformation of human mesenchymal cells and skin fibroblasts into hematopoietic cells. (Harris DM, Hazan-Haley I, Coombes K, Bueso-Ramos C, Liu J, Liu Z, Li P, Ravoori M, Abruzzo L, Han L, Singh S, Sun M, Kundra V, Kurzrock R, Estrov Z) PLoS One 2011;6(6):e21250 31 Citations |
| 1 | PKCα mediates acetylcholine-induced activation of TRPV4-dependent calcium influx in endothelial cells. (Adapala RK, Talasila PK, Bratz IN, Zhang DX, Suzuki M, Meszaros JG, Thodeti CK) Am J Physiol Heart Circ Physiol 2011 Sep;301(3):H757-65 87 Citations |
| 3 | Platelet gene therapy improves hemostatic function for integrin alphaIIbbeta3-deficient dogs. (Fang J, Jensen ES, Boudreaux MK, Du LM, Hawkins TB, Koukouritaki SB, Cornetta K, Wilcox DA) Proc Natl Acad Sci U S A 2011 Jun 07;108(23):9583-8 51 Citations |
| 1 | Ubiquitination of GPCRs. (Caballero A, Marchese A) Methods Mol Biol 2011;746:251-9 5 Citations |
| 1 | Targeted methylation of two tumor suppressor genes is sufficient to transform mesenchymal stem cells into cancer stem/initiating cells. (Teng IW, Hou PC, Lee KD, Chu PY, Yeh KT, Jin VX, Tseng MJ, Tsai SJ, Chang YS, Wu CS, Sun HS, Tsai KD, Jeng LB, Nephew KP, Huang TH, Hsiao SH, Leu YW) Cancer Res 2011 Jul 01;71(13):4653-63 93 Citations |
| 1 | The protective effect of overexpression of extracellular superoxide dismutase on nitric oxide bioavailability in the lung after exposure to hyperoxia stress. (Ahmed MN, Codipilly C, Hogg N, Auten RL) Exp Lung Res 2011 Feb;37(1):10-7 24 Citations |
| 2 | Pancreatic stellate cell models for transcriptional studies of desmoplasia-associated genes. (Mathison A, Liebl A, Bharucha J, Mukhopadhyay D, Lomberk G, Shah V, Urrutia R) Pancreatology 2010;10(4):505-16 |
| 1 | Plk2 attachment to NSF induces homeostatic removal of GluA2 during chronic overexcitation. (Evers DM, Matta JA, Hoe HS, Zarkowsky D, Lee SH, Isaac JT, Pak DT) Nat Neurosci 2010 Oct;13(10):1199-207 57 Citations |
| 1 | A flexible multiwell format for immunofluorescence screening microscopy of small-molecule inhibitors. (Scholz AK, Klebl BM, Morkel M, Lehrach H, Dahl A, Lange BM) Assay Drug Dev Technol 2010 Oct;8(5):571-80 3 Citations |
| 1 | Combinatorial chemoprevention reveals a novel smoothened-independent role of GLI1 in esophageal carcinogenesis. (Ilyas SI, Demars CJ, Comba A, Gainullin VG, Rizvi Z, Almada LL, Wang K, Lomberk G, Fernández-Zapico ME, Buttar NS) Cancer Res 2010 Sep 01;70(17):6787-96 43 Citations |
| 1 | Leukemia inhibitory factor can mediate Ras/Raf/MEK/ERK-induced growth inhibitory signaling in medullary thyroid cancer cells. (Arthan D, Hong SK, Park JI) Cancer Lett 2010 Nov 01;297(1):31-41 47 Citations |
| 1 | Polymorphic variation in cytochrome oxidase subunit genes. (Lu J, Wang K, Rodova M, Esteves R, Berry D, E L, Crafter A, Barrett M, Cardoso SM, Onyango I, Parker WD, Fontes J, Burns JM, Swerdlow RH) J Alzheimers Dis 2010;21(1):141-54 30 Citations |
| 1 | Pigment epithelium-derived factor stimulates tumor macrophage recruitment and is downregulated by the prostate tumor microenvironment. (Halin S, Rudolfsson SH, Doll JA, Crawford SE, Wikström P, Bergh A) Neoplasia 2010 Apr;12(4):336-45 41 Citations |
| 1 | The effect of tyrosine nitration of L-type Ca2+ channels on excitation-transcription coupling in colonic inflammation. (Kang M, Ross GR, Akbarali HI) Br J Pharmacol 2010 Mar;159(6):1226-35 19 Citations |
| 2 | Endothelial cell-specific chemotaxis receptor (ecscr) promotes angioblast migration during vasculogenesis and enhances VEGF receptor sensitivity. (Verma A, Bhattacharya R, Remadevi I, Li K, Pramanik K, Samant GV, Horswill M, Chun CZ, Zhao B, Wang E, Miao RQ, Mukhopadhyay D, Ramchandran R, Wilkinson GA) Blood 2010 Jun 03;115(22):4614-22 32 Citations |
| 1 | Reduced sox9 function promotes heart valve calcification phenotypes in vivo. (Peacock JD, Levay AK, Gillaspie DB, Tao G, Lincoln J) Circ Res 2010 Mar 05;106(4):712-9 108 Citations |
| 2 | TRPV4-mediated endothelial Ca2+ influx and vasodilation in response to shear stress. (Mendoza SA, Fang J, Gutterman DD, Wilcox DA, Bubolz AH, Li R, Suzuki M, Zhang DX) Am J Physiol Heart Circ Physiol 2010 Feb;298(2):H466-76 282 Citations |
| 1 | Molecular determinants dictating cell surface expression of the human sodium-dependent vitamin C transporter-2 in human liver cells. (Subramanian VS, Marchant JS, Said HM) Am J Physiol Gastrointest Liver Physiol 2010 Feb;298(2):G267-74 18 Citations |
| 1 | Synthetic cannabinoid receptor agonists inhibit tumor growth and metastasis of breast cancer. (Qamri Z, Preet A, Nasser MW, Bass CE, Leone G, Barsky SH, Ganju RK) Mol Cancer Ther 2009 Nov;8(11):3117-29 205 Citations |
| 1 | Generation of mesenchymal stromal cells from HOXB4-expressing human embryonic stem cells. (Liu YP, Hematti P) Cytotherapy 2009;11(6):716-25 7 Citations |
| 1 | Identification and characterization of a novel ABCA3 mutation. (Park SK, Amos L, Rao A, Quasney MW, Matsumura Y, Inagaki N, Dahmer MK) Physiol Genomics 2010 Jan 08;40(2):94-9 17 Citations |
| 1 | Facilitative glucose transporter 9 expression affects glucose sensing in pancreatic beta-cells. (Evans SA, Doblado M, Chi MM, Corbett JA, Moley KH) Endocrinology 2009 Dec;150(12):5302-10 46 Citations |
| 1 | Noncatalytic function of ERK1/2 can promote Raf/MEK/ERK-mediated growth arrest signaling. (Hong SK, Yoon S, Moelling C, Arthan D, Park JI) J Biol Chem 2009 Nov 27;284(48):33006-18 74 Citations |
| 2 | Identification and functional characterization of phosphorylation sites on GTP cyclohydrolase I. (Du J, Wei N, Xu H, Ge Y, Vásquez-Vivar J, Guan T, Oldham KT, Pritchard KA Jr, Shi Y) Arterioscler Thromb Vasc Biol 2009 Dec;29(12):2161-8 11 Citations |
| 1 | Ubiquitination regulates proteolytic processing of G protein-coupled receptors after their sorting to lysosomes. (Hislop JN, Henry AG, Marchese A, von Zastrow M) J Biol Chem 2009 Jul 17;284(29):19361-70 76 Citations |
| 1 | The enhanced hypercalcemic response to 20-epi-1,25-dihydroxyvitamin D3 results from a selective and prolonged induction of intestinal calcium-regulating genes. (Zella LA, Meyer MB, Nerenz RD, Pike JW) Endocrinology 2009 Aug;150(8):3448-56 25 Citations |
| 1 | Epidermal growth factor activates Na(+/)H(+) exchanger in podocytes through a mechanism that involves Janus kinase and calmodulin. (Coaxum SD, Garnovskaya MN, Gooz M, Baldys A, Raymond JR) Biochim Biophys Acta 2009 Jul;1793(7):1174-81 46 Citations |
| 1 | Role of nuclear-encoded subunit Vb in the assembly and stability of cytochrome c oxidase complex: implications in mitochondrial dysfunction and ROS production. (Galati D, Srinivasan S, Raza H, Prabu SK, Hardy M, Chandran K, Lopez M, Kalyanaraman B, Avadhani NG) Biochem J 2009 May 27;420(3):439-49 79 Citations |
| 1 | The major human pregnane X receptor (PXR) splice variant, PXR.2, exhibits significantly diminished ligand-activated transcriptional regulation. (Lin YS, Yasuda K, Assem M, Cline C, Barber J, Li CW, Kholodovych V, Ai N, Chen JD, Welsh WJ, Ekins S, Schuetz EG) Drug Metab Dispos 2009 Jun;37(6):1295-304 35 Citations |
| 1 | Membrane targeting and intracellular trafficking of the human sodium-dependent multivitamin transporter in polarized epithelial cells. (Subramanian VS, Marchant JS, Boulware MJ, Ma TY, Said HM) Am J Physiol Cell Physiol 2009 Apr;296(4):C663-71 38 Citations |
| 1 | Vasculostatin inhibits intracranial glioma growth and negatively regulates in vivo angiogenesis through a CD36-dependent mechanism. (Kaur B, Cork SM, Sandberg EM, Devi NS, Zhang Z, Klenotic PA, Febbraio M, Shim H, Mao H, Tucker-Burden C, Silverstein RL, Brat DJ, Olson JJ, Van Meir EG) Cancer Res 2009 Feb 01;69(3):1212-20 99 Citations |
| 1 | Proteasome-mediated degradation and functions of hematopoietic progenitor kinase 1 in pancreatic cancer. (Wang H, Song X, Logsdon C, Zhou G, Evans DB, Abbruzzese JL, Hamilton SR, Tan TH, Wang H) Cancer Res 2009 Feb 01;69(3):1063-70 30 Citations |
| 1 | Corneal stroma PDGF blockade and myofibroblast development. (Kaur H, Chaurasia SS, de Medeiros FW, Agrawal V, Salomao MQ, Singh N, Ambati BK, Wilson SE) Exp Eye Res 2009 May;88(5):960-5 51 Citations |
| 1 | Two supporting factors greatly improve the efficiency of human iPSC generation. (Zhao Y, Yin X, Qin H, Zhu F, Liu H, Yang W, Zhang Q, Xiang C, Hou P, Song Z, Liu Y, Yong J, Zhang P, Cai J, Liu M, Li H, Li Y, Qu X, Cui K, Zhang W, Xiang T, Wu Y, Zhao Y, Liu C, Yu C, Yuan K, Lou J, Ding M, Deng H) Cell Stem Cell 2008 Nov 06;3(5):475-9 414 Citations |
| 1 | SmgGDS is up-regulated in prostate carcinoma and promotes tumour phenotypes in prostate cancer cells. (Zhi H, Yang XJ, Kuhnmuench J, Berg T, Thill R, Yang H, See WA, Becker CG, Williams CL, Li R) J Pathol 2009 Feb;217(3):389-97 22 Citations |
| 1 | Molecular characterization of a novel cell surface ADP-ribosyl cyclase from the sea urchin. (Churamani D, Boulware MJ, Ramakrishnan L, Geach TJ, Martin AC, Vacquier VD, Marchant JS, Dale L, Patel S) Cell Signal 2008 Dec;20(12):2347-55 13 Citations |
| 1 | Upstream stimulatory factor is required for human angiotensinogen expression and differential regulation by the A-20C polymorphism. (Dickson ME, Tian X, Liu X, Davis DR, Sigmund CD) Circ Res 2008 Oct 24;103(9):940-7 17 Citations |
| 1 | Polymeric gene delivery of ischemia-inducible VEGF significantly attenuates infarct size and apoptosis following myocardial infarct. (Yockman JW, Choi D, Whitten MG, Chang CW, Kastenmeier A, Erickson H, Albanil A, Lee M, Kim SW, Bull DA) Gene Ther 2009 Jan;16(1):127-35 55 Citations |
| 1 | IL-10 secretion increases signal persistence of HEMA-MMA-microencapsulated luciferase-modified CHO fibroblasts in mice. (Surzyn M, Symes J, Medin JA, Sefton MV) Tissue Eng Part A 2009 Jan;15(1):127-36 11 Citations |
| 1 | Liposome-mediated transfection with extract from neonatal rat cardiomyocytes induces transdifferentiation of human adipose-derived stem cells into cardiomyocytes. (Schimrosczyk K, Song YH, Vykoukal J, Vykoukal D, Bai X, Coleman M, Krohn A, Freyberg S, Alt EU) Scand J Clin Lab Invest 2008;68(6):464-72 8 Citations |
| 2 | Expression and function of fatty acid amide hydrolase in prostate cancer. (Endsley MP, Thill R, Choudhry I, Williams CL, Kajdacsy-Balla A, Campbell WB, Nithipatikom K) Int J Cancer 2008 Sep 15;123(6):1318-26 85 Citations |
| 1 | Constitutive CXCL12 expression induces anoikis in colorectal carcinoma cells. (Wendt MK, Drury LJ, Vongsa RA, Dwinell MB) Gastroenterology 2008 Aug;135(2):508-17 46 Citations |
| 2 | Identification and characterization of the unique guanine nucleotide exchange factor, SmgGDS, in vascular smooth muscle cells. (Thill R, Campbell WB, Williams CL) J Cell Biochem 2008 Aug 01;104(5):1760-70 6 Citations |
| 1 | Protein kinase A-dependent phosphorylation modulates beta1Pix guanine nucleotide exchange factor activity through 14-3-3beta binding. (Chahdi A, Sorokin A) Mol Cell Biol 2008 Mar;28(5):1679-87 40 Citations |
| 1 | Alternatively spliced human tissue factor promotes tumor growth and angiogenesis in a pancreatic cancer tumor model. (Hobbs JE, Zakarija A, Cundiff DL, Doll JA, Hymen E, Cornwell M, Crawford SE, Liu N, Signaevsky M, Soff GA) Thromb Res 2007;120 Suppl 2:S13-21 81 Citations |
| 1 | Apical membrane targeting and trafficking of the human proton-coupled transporter in polarized epithelia. (Subramanian VS, Marchant JS, Said HM) Am J Physiol Cell Physiol 2008 Jan;294(1):C233-40 43 Citations |
| 1 | SmgGDS regulates cell proliferation, migration, and NF-kappaB transcriptional activity in non-small cell lung carcinoma. (Tew GW, Lorimer EL, Berg TJ, Zhi H, Li R, Williams CL) J Biol Chem 2008 Jan 11;283(2):963-76 59 Citations |
| 1 | The role of nitric oxide and the unfolded protein response in cytokine-induced beta-cell death. (Chambers KT, Unverferth JA, Weber SM, Wek RC, Urano F, Corbett JA) Diabetes 2008 Jan;57(1):124-32 72 Citations |
| 1 | Domain 5 of the cation-independent mannose 6-phosphate receptor preferentially binds phosphodiesters (mannose 6-phosphate N-acetylglucosamine ester). (Chavez CA, Bohnsack RN, Kudo M, Gotschall RR, Canfield WM, Dahms NM) Biochemistry 2007 Nov 06;46(44):12604-17 44 Citations |
| 1 | The cardioprotective effect of mesenchymal stem cells is mediated by IGF-I and VEGF. (Sadat S, Gehmert S, Song YH, Yen Y, Bai X, Gaiser S, Klein H, Alt E) Biochem Biophys Res Commun 2007 Nov 23;363(3):674-9 284 Citations |
| 1 | Tight junction targeting and intracellular trafficking of occludin in polarized epithelial cells. (Subramanian VS, Marchant JS, Ye D, Ma TY, Said HM) Am J Physiol Cell Physiol 2007 Nov;293(5):C1717-26 31 Citations |
| 2 | p38alpha antagonizes p38gamma activity through c-Jun-dependent ubiquitin-proteasome pathways in regulating Ras transformation and stress response. (Qi X, Pohl NM, Loesch M, Hou S, Li R, Qin JZ, Cuenda A, Chen G) J Biol Chem 2007 Oct 26;282(43):31398-408 55 Citations |
| 1 | Human bullous pemphigoid antigen 2 transgenic skin elicits specific IgG in wild-type mice. (Olasz EB, Roh J, Yee CL, Arita K, Akiyama M, Shimizu H, Vogel JC, Yancey KB) J Invest Dermatol 2007 Dec;127(12):2807-17 33 Citations |
| 1 | Downregulation of Sirt1 by antisense oligonucleotides induces apoptosis and enhances radiation sensitization in A549 lung cancer cells. (Sun Y, Sun D, Li F, Tian L, Li C, Li L, Lin R, Wang S) Lung Cancer 2007 Oct;58(1):21-9 68 Citations |
| 1 | Mutant ubiquitin found in Alzheimer's disease causes neuritic beading of mitochondria in association with neuronal degeneration. (Tan Z, Sun X, Hou FS, Oh HW, Hilgenberg LG, Hol EM, van Leeuwen FW, Smith MA, O'Dowd DK, Schreiber SS) Cell Death Differ 2007 Oct;14(10):1721-32 74 Citations |
| 1 | Vitamin B1 (thiamine) uptake by human retinal pigment epithelial (ARPE-19) cells: mechanism and regulation. (Subramanian VS, Mohammed ZM, Molina A, Marchant JS, Vaziri ND, Said HM) J Physiol 2007 Jul 01;582(Pt 1):73-85 30 Citations |
| 1 | Engineered human tmpk/AZT as a novel enzyme/prodrug axis for suicide gene therapy. (Sato T, Neschadim A, Konrad M, Fowler DH, Lavie A, Medin JA) Mol Ther 2007 May;15(5):962-70 88 Citations |
| 1 | Targeting and intracellular trafficking of clinically relevant hTHTR1 mutations in human cell lines. (Subramanian VS, Marchant JS, Said HM) Clin Sci (Lond) 2007 Jul;113(2):93-102 16 Citations |
| 2 | Efficient transgenic rat production by a lentiviral vector. (Michalkiewicz M, Michalkiewicz T, Geurts AM, Roman RJ, Slocum GR, Singer O, Weihrauch D, Greene AS, Kaldunski M, Verma IM, Jacob HJ, Cowley AW Jr) Am J Physiol Heart Circ Physiol 2007 Jul;293(1):H881-94 37 Citations |
| 1 | Differential roles of Rap1 and Rap2 small GTPases in neurite retraction and synapse elimination in hippocampal spiny neurons. (Fu Z, Lee SH, Simonetta A, Hansen J, Sheng M, Pak DT) J Neurochem 2007 Jan;100(1):118-31 72 Citations |
| 1 | Functional characterization of polymorphisms in the kidney enhancer of the human renin gene. (Itani HA, Liu X, Pratt JH, Sigmund CD) Endocrinology 2007 Mar;148(3):1424-30 18 Citations |
| 2 | Stress-induced c-Jun-dependent Vitamin D receptor (VDR) activation dissects the non-classical VDR pathway from the classical VDR activity. (Li QP, Qi X, Pramanik R, Pohl NM, Loesch M, Chen G) J Biol Chem 2007 Jan 19;282(3):1544-51 30 Citations |
| 2 | The cell-adhesion and signaling molecule PECAM-1 is a molecular mediator of resistance to genotoxic chemotherapy. (Bergom C, Goel R, Paddock C, Gao C, Newman DK, Matsuyama S, Newman PJ) Cancer Biol Ther 2006 Dec;5(12):1699-707 27 Citations |
| 1 | Genetic ablation of angiotensinogen in the subfornical organ of the brain prevents the central angiotensinergic pressor response. (Sinnayah P, Lazartigues E, Sakai K, Sharma RV, Sigmund CD, Davisson RL) Circ Res 2006 Nov 10;99(10):1125-31 40 Citations |
| 1 | Human papillomaviruses target the double-stranded RNA protein kinase pathway. (Hebner CM, Wilson R, Rader J, Bidder M, Laimins LA) J Gen Virol 2006 Nov;87(Pt 11):3183-3193 58 Citations |
| 1 | Zinc induces ERK-dependent cell death through a specific Ras isoform. (Klein C, Creach K, Irintcheva V, Hughes KJ, Blackwell PL, Corbett JA, Baldassare JJ) Apoptosis 2006 Nov;11(11):1933-44 28 Citations |
| 1 | Proteomic analysis of acute promyelocytic leukemia: PML-RARalpha leads to decreased phosphorylation of OP18 at serine 63. (Zada AA, Geletu MH, Pulikkan JA, Müller-Tidow C, Reddy VA, Christopeit M, Hiddemann WD, Behre HM, Tenen DG, Behre G) Proteomics 2006 Nov;6(21):5705-19 14 Citations |
| 1 | FGF19 is a target for FOXC1 regulation in ciliary body-derived cells. (Tamimi Y, Skarie JM, Footz T, Berry FB, Link BA, Walter MA) Hum Mol Genet 2006 Nov 01;15(21):3229-40 41 Citations |
| 1 | A novel endothelial-specific heat shock protein HspA12B is required in both zebrafish development and endothelial functions in vitro. (Hu G, Tang J, Zhang B, Lin Y, Hanai J, Galloway J, Bedell V, Bahary N, Han Z, Ramchandran R, Thisse B, Thisse C, Zon LI, Sukhatme VP) J Cell Sci 2006 Oct 01;119(Pt 19):4117-26 62 Citations |
| 1 | Distinct biological impact of dephosphorylation vs. downregulation of p210Bcr-Abl: implications for imatinib mesylate response and resistance. (Kurzrock R, Talpaz M, Li L, Estrov Z) Leuk Lymphoma 2006 Aug;47(8):1651-64 2 Citations |
| 1 | Interleukin-1beta attenuates renin gene expression via a mitogen-activated protein kinase kinase-extracellular signal-regulated kinase and signal transducer and activator of transcription 3-dependent mechanism in As4.1 cells. (Liu X, Shi Q, Sigmund CD) Endocrinology 2006 Dec;147(12):6011-8 24 Citations |
| 1 | Identification of genes regulated by Wnt/beta-catenin pathway and involved in apoptosis via microarray analysis. (Huang M, Wang Y, Sun D, Zhu H, Yin Y, Zhang W, Yang S, Quan L, Bai J, Wang S, Chen Q, Li S, Xu N) BMC Cancer 2006 Sep 07;6:221 47 Citations |
| 2 | p38gamma mitogen-activated protein kinase integrates signaling crosstalk between Ras and estrogen receptor to increase breast cancer invasion. (Qi X, Tang J, Loesch M, Pohl N, Alkan S, Chen G) Cancer Res 2006 Aug 01;66(15):7540-7 41 Citations |
| 1 | Evolution of melanopsin photoreceptors: discovery and characterization of a new melanopsin in nonmammalian vertebrates. (Bellingham J, Chaurasia SS, Melyan Z, Liu C, Cameron MA, Tarttelin EE, Iuvone PM, Hankins MW, Tosini G, Lucas RJ) PLoS Biol 2006 Jul;4(8):e254 169 Citations |
| 1 | Proteasome-dependent down-regulation of activated Stat5A in the nucleus. (Chen Y, Dai X, Haas AL, Wen R, Wang D) Blood 2006 Jul 15;108(2):566-74 24 Citations |
| 1 | Robo4 signaling in endothelial cells implies attraction guidance mechanisms. (Kaur S, Castellone MD, Bedell VM, Konar M, Gutkind JS, Ramchandran R) J Biol Chem 2006 Apr 21;281(16):11347-56 79 Citations |
| 1 | Targeting and trafficking of the human thiamine transporter-2 in epithelial cells. (Subramanian VS, Marchant JS, Said HM) J Biol Chem 2006 Feb 24;281(8):5233-45 35 Citations |
| 1 | Discovery of small molecule inhibitors of the interaction of the thyroid hormone receptor with transcriptional coregulators. (Arnold LA, Estébanez-Perpiñá E, Togashi M, Jouravel N, Shelat A, McReynolds AC, Mar E, Nguyen P, Baxter JD, Fletterick RJ, Webb P, Guy RK) J Biol Chem 2005 Dec 30;280(52):43048-55 96 Citations |
| 1 | Transgenic expression of a dominant-negative ASIC3 subunit leads to increased sensitivity to mechanical and inflammatory stimuli. (Mogil JS, Breese NM, Witty MF, Ritchie J, Rainville ML, Ase A, Abbadi N, Stucky CL, Séguéla P) J Neurosci 2005 Oct 26;25(43):9893-901 112 Citations |
| 2 | Sepiapterin attenuates 1-methyl-4-phenylpyridinium-induced apoptosis in neuroblastoma cells transfected with neuronal NOS: role of tetrahydrobiopterin, nitric oxide, and proteasome activation. (Shang T, Kotamraju S, Zhao H, Kalivendi SV, Hillard CJ, Kalyanaraman B) Free Radic Biol Med 2005 Oct 15;39(8):1059-74 32 Citations |
| 1 | Maternal alloimmunization against the rare platelet-specific antigen HPA-9b (Max a) is an important cause of neonatal alloimmune thrombocytopenia. (Peterson JA, Balthazor SM, Curtis BR, McFarland JG, Aster RH) Transfusion 2005 Sep;45(9):1487-95 56 Citations |
| 1 | Neuroblastoma cells transiently transfected to simultaneously express the co-stimulatory molecules CD54, CD80, CD86, and CD137L generate antitumor immunity in mice. (Johnson BD, Gershan JA, Natalia N, Zujewski H, Weber JJ, Yan X, Orentas RJ) J Immunother 2005;28(5):449-60 32 Citations |
| 1 | Specific pharmacological dimerization of KDR in lentivirally transduced human hematopoietic cells activates anti-apoptotic and proliferative mechanisms. (Siatskas C, Underwood J, Ramezani A, Hawley RG, Medin JA) FASEB J 2005 Oct;19(12):1752-4 10 Citations |
| 1 | Overexpression of neuropilin-1 promotes constitutive MAPK signalling and chemoresistance in pancreatic cancer cells. (Wey JS, Gray MJ, Fan F, Belcheva A, McCarty MF, Stoeltzing O, Somcio R, Liu W, Evans DB, Klagsbrun M, Gallick GE, Ellis LM) Br J Cancer 2005 Jul 25;93(2):233-41 108 Citations |
| 1 | IFI16 is an essential mediator of growth inhibition, but not differentiation, induced by the leukemia inhibitory factor/JAK/STAT pathway in medullary thyroid carcinoma cells. (Kim EJ, Park JI, Nelkin BD) J Biol Chem 2005 Feb 11;280(6):4913-20 49 Citations |
| 1 | Unanticipated antigens: translation initiation at CUG with leucine. (Schwab SR, Shugart JA, Horng T, Malarkannan S, Shastri N) PLoS Biol 2004 Nov;2(11):e366 91 Citations |
| 1 | Leucine culture reveals that ATP synthase functions as a fuel sensor in pancreatic beta-cells. (Yang J, Wong RK, Wang X, Moibi J, Hessner MJ, Greene S, Wu J, Sukumvanich S, Wolf BA, Gao Z) J Biol Chem 2004 Dec 24;279(52):53915-23 33 Citations |
| 1 | Calcium-dependent dephosphorylation mediates the hyperosmotic and lysophosphatidic acid-dependent inhibition of natriuretic peptide receptor-B/guanylyl cyclase-B. (Potthast R, Abbey-Hosch SE, Antos LK, Marchant JS, Kuhn M, Potter LR) J Biol Chem 2004 Nov 19;279(47):48513-9 33 Citations |
| 1 | PXR (NR1I2): splice variants in human tissues, including brain, and identification of neurosteroids and nicotine as PXR activators. (Lamba V, Yasuda K, Lamba JK, Assem M, Davila J, Strom S, Schuetz EG) Toxicol Appl Pharmacol 2004 Sep 15;199(3):251-65 185 Citations |
| 1 | Arachidonic acid-induced carbon-centered radicals and phospholipid peroxidation in cyclo-oxygenase-2-transfected PC12 cells. (Jiang J, Borisenko GG, Osipov A, Martin I, Chen R, Shvedova AA, Sorokin A, Tyurina YY, Potapovich A, Tyurin VA, Graham SH, Kagan VE) J Neurochem 2004 Sep;90(5):1036-49 63 Citations |
| 1 | ExoS Rho GTPase-activating protein activity stimulates reorganization of the actin cytoskeleton through Rho GTPase guanine nucleotide disassociation inhibitor. (Sun J, Barbieri JT) J Biol Chem 2004 Oct 08;279(41):42936-44 30 Citations |
| 1 | Aberrant regulation of survivin by the RB/E2F family of proteins. (Jiang Y, Saavedra HI, Holloway MP, Leone G, Altura RA) J Biol Chem 2004 Sep 24;279(39):40511-20 152 Citations |
| 1 | Ezrin/radixin/moesin proteins are high affinity targets for ADP-ribosylation by Pseudomonas aeruginosa ExoS. (Maresso AW, Baldwin MR, Barbieri JT) J Biol Chem 2004 Sep 10;279(37):38402-8 55 Citations |
| 1 | Localization and function of the brain excitatory amino acid transporter type 1 in cardiac mitochondria. (Ralphe JC, Segar JL, Schutte BC, Scholz TD) J Mol Cell Cardiol 2004 Jul;37(1):33-41 43 Citations |
| 1 | The 3'-untranslated region of the beta2-adrenergic receptor mRNA regulates receptor synthesis. (Subramaniam K, Chen K, Joseph K, Raymond JR, Tholanikunnel BG) J Biol Chem 2004 Jun 25;279(26):27108-15 26 Citations |
| 1 | Quality control in the apoA-I secretory pathway: deletion of apoA-I helix 6 leads to the formation of cytosolic phospholipid inclusions. (Bhat S, Zabalawi M, Willingham MC, Shelness GS, Thomas MJ, Sorci-Thomas MG) J Lipid Res 2004 Jul;45(7):1207-20 10 Citations |
| 2 | p38 MAPK activation selectively induces cell death in K-ras-mutated human colon cancer cells through regulation of vitamin D receptor. (Qi X, Tang J, Pramanik R, Schultz RM, Shirasawa S, Sasazuki T, Han J, Chen G) J Biol Chem 2004 May 21;279(21):22138-44 60 Citations |
| 1 | Interactions between hepatic Mrp4 and Sult2a as revealed by the constitutive androstane receptor and Mrp4 knockout mice. (Assem M, Schuetz EG, Leggas M, Sun D, Yasuda K, Reid G, Zelcer N, Adachi M, Strom S, Evans RM, Moore DD, Borst P, Schuetz JD) J Biol Chem 2004 May 21;279(21):22250-7 219 Citations |
| 1 | Analysis of two translocation breakpoints and identification of a negative regulatory element in patients with Rieger's syndrome. (Trembath DG, Semina EV, Jones DH, Patil SR, Qian Q, Amendt BA, Russo AF, Murray JC) Birth Defects Res A Clin Mol Teratol 2004 Feb;70(2):82-91 21 Citations |
| 1 | Calmodulin interacts with the third intracellular loop of the serotonin 5-hydroxytryptamine1A receptor at two distinct sites: putative role in receptor phosphorylation by protein kinase C. (Turner JH, Gelasco AK, Raymond JR) J Biol Chem 2004 Apr 23;279(17):17027-37 75 Citations |
| 2 | Alpha-synuclein up-regulation and aggregation during MPP+-induced apoptosis in neuroblastoma cells: intermediacy of transferrin receptor iron and hydrogen peroxide. (Kalivendi SV, Cunningham S, Kotamraju S, Joseph J, Hillard CJ, Kalyanaraman B) J Biol Chem 2004 Apr 09;279(15):15240-7 125 Citations |
| 1 | Membrane-potential-dependent inhibition of platelet adhesion to endothelial cells by epoxyeicosatrienoic acids. (Krötz F, Riexinger T, Buerkle MA, Nithipatikom K, Gloe T, Sohn HY, Campbell WB, Pohl U) Arterioscler Thromb Vasc Biol 2004 Mar;24(3):595-600 113 Citations |
| 1 | Unexpected sensitivity of synthetic Renilla luciferase control vectors to treatment with a cyclopentenone prostaglandin. (Zhang X, Chen HZ, Rovin BH) Biotechniques 2003 Dec;35(6):1144-6, 1148 4 Citations |
| 1 | An improved growth hormone reporter gene shows a different pattern of transactivation by promoter fragments. (Schembri-Wismayer P, Birnie GD) Gene 2003 Dec 24;323:173-80 1 Citation |
| 2 | Estrogen receptor inhibits c-Jun-dependent stress-induced cell death by binding and modifying c-Jun activity in human breast cancer cells. (Qi X, Borowicz S, Pramanik R, Schultz RM, Han J, Chen G) J Biol Chem 2004 Feb 20;279(8):6769-77 29 Citations |
| 1 | Expression and functional contribution of hTHTR-2 in thiamin absorption in human intestine. (Said HM, Balamurugan K, Subramanian VS, Marchant JS) Am J Physiol Gastrointest Liver Physiol 2004 Mar;286(3):G491-8 118 Citations |
| 1 | Impact of p210(Bcr-Abl) on ultraviolet C wavelength-induced DNA damage and repair. (Laurent E, Mitchell DL, Estrov Z, Lowery M, Tucker SL, Talpaz M, Kurzrock R) Clin Cancer Res 2003 Sep 01;9(10 Pt 1):3722-30 12 Citations |
| 1 | Phosphorylation of threonine 497 in endothelial nitric-oxide synthase coordinates the coupling of L-arginine metabolism to efficient nitric oxide production. (Lin MI, Fulton D, Babbitt R, Fleming I, Busse R, Pritchard KA Jr, Sessa WC) J Biol Chem 2003 Nov 07;278(45):44719-26 221 Citations |
| 1 | Decreased PMCA4b expression has no effect on calcium homeostasis in Meg-01 cells. (Wan TC, Dean WL) Platelets 2003 Aug;14(5):295-303 3 Citations |
| 1 | Identification and characterization of E2F7, a novel mammalian E2F family member capable of blocking cellular proliferation. (de Bruin A, Maiti B, Jakoi L, Timmers C, Buerki R, Leone G) J Biol Chem 2003 Oct 24;278(43):42041-9 180 Citations |
| 1 | CrkIII: a novel and biologically distinct member of the Crk family of adaptor proteins. (Prosser S, Sorokina E, Pratt P, Sorokin A) Oncogene 2003 Jul 31;22(31):4799-806 27 Citations |
| 1 | JUMONJI, a critical factor for cardiac development, functions as a transcriptional repressor. (Kim TG, Kraus JC, Chen J, Lee Y) J Biol Chem 2003 Oct 24;278(43):42247-55 82 Citations |
| 1 | Gene transfer into genomes of human cells by the sleeping beauty transposon system. (Geurts AM, Yang Y, Clark KJ, Liu G, Cui Z, Dupuy AJ, Bell JB, Largaespada DA, Hackett PB) Mol Ther 2003 Jul;8(1):108-17 310 Citations |
| 1 | Polycystin-1 distribution is modulated by polycystin-2 expression in mammalian cells. (Grimm DH, Cai Y, Chauvet V, Rajendran V, Zeltner R, Geng L, Avner ED, Sweeney W, Somlo S, Caplan MJ) J Biol Chem 2003 Sep 19;278(38):36786-93 77 Citations |
| 1 | BMP-7 counteracts TGF-beta1-induced epithelial-to-mesenchymal transition and reverses chronic renal injury. (Zeisberg M, Hanai J, Sugimoto H, Mammoto T, Charytan D, Strutz F, Kalluri R) Nat Med 2003 Jul;9(7):964-8 1234 Citations |
| 1 | Dual expression of CD80 and CD86 produces a tumor vaccine superior to single expression of either molecule. (Johnson BD, Yan X, Schauer DW, Orentas RJ) Cell Immunol 2003 Mar;222(1):15-26 29 Citations |
| 1 | Localized recruitment of a chromatin-remodeling activity by an activator in vivo drives transcriptional elongation. (Corey LL, Weirich CS, Benjamin IJ, Kingston RE) Genes Dev 2003 Jun 01;17(11):1392-401 119 Citations |
| 2 | Expression of human factor VIII under control of the platelet-specific alphaIIb promoter in megakaryocytic cell line as well as storage together with VWF. (Shi Q, Wilcox DA, Fahs SA, Kroner PA, Montgomery RR) Mol Genet Metab 2003 May;79(1):25-33 45 Citations |
| 1 | AP-4F, antennapedia peptide linked to an amphipathic alpha helical peptide, increases the efficiency of Lipofectamine-mediated gene transfection in endothelial cells. (Ou J, Geiger T, Ou Z, Ackerman AW, Oldham KT, Pritchard KA Jr) Biochem Biophys Res Commun 2003 Jun 06;305(3):605-10 15 Citations |
| 1 | Bleeding due to disruption of a cargo-specific ER-to-Golgi transport complex. (Zhang B, Cunningham MA, Nichols WC, Bernat JA, Seligsohn U, Pipe SW, McVey JH, Schulte-Overberg U, de Bosch NB, Ruiz-Saez A, White GC, Tuddenham EG, Kaufman RJ, Ginsburg D) Nat Genet 2003 Jun;34(2):220-5 243 Citations |
| 1 | The absence of functional glucosylceramide synthase does not sensitize melanoma cells for anticancer drugs. (Veldman RJ, Mita A, Cuvillier O, Garcia V, Klappe K, Medin JA, Campbell JD, Carpentier S, Kok JW, Levade T) FASEB J 2003 Jun;17(9):1144-6 40 Citations |
| 1 | The CBP bromodomain and nucleosome targeting are required for Zta-directed nucleosome acetylation and transcription activation. (Deng Z, Chen CJ, Chamberlin M, Lu F, Blobel GA, Speicher D, Cirillo LA, Zaret KS, Lieberman PM) Mol Cell Biol 2003 Apr;23(8):2633-44 43 Citations |
| 1 | Efficiency of chimeraplast gene targeting by direct nuclear injection using a GFP recovery assay. (Tran ND, Liu X, Yan Z, Abbote D, Jiang Q, Kmiec EB, Sigmund CD, Engelhardt JF) Mol Ther 2003 Feb;7(2):248-53 38 Citations |
| 1 | Bcl-2 reduces mutant rates in a transgenic lacZ reporter gene in mouse pre-B lymphocytes. (Felix K, Rolink A, Melchers F, Janz S) Mutat Res 2003 Jan 28;522(1-2):135-44 3 Citations |
| 1 | Suppression of tumorigenesis and induction of p15(ink4b) by Smad4/DPC4 in human pancreatic cancer cells. (Peng B, Fleming JB, Breslin T, Grau AM, Fojioka S, Abbruzzese JL, Evans DB, Ayers D, Wathen K, Wu T, Robertson KD, Chiao PJ) Clin Cancer Res 2002 Nov;8(11):3628-38 59 Citations |
| 1 | Retroviral transduction efficiency of G-CSF+SCF-mobilized peripheral blood CD34+ cells is superior to G-CSF or G-CSF+Flt3-L-mobilized cells in nonhuman primates. (Hematti P, Sellers SE, Agricola BA, Metzger ME, Donahue RE, Dunbar CE) Blood 2003 Mar 15;101(6):2199-205 46 Citations |
| 2 | Hyperresistance to photosensitized lipid peroxidation and apoptotic killing in 5-aminolevulinate-treated tumor cells overexpressing mitochondrial GPX4. (Kriska T, Korytowski W, Girotti AW) Free Radic Biol Med 2002 Nov 15;33(10):1389-402 56 Citations |
| 1 | Endothelin signalling and regulation of protein kinases in glomerular mesangial cells. (Sorokin A, Foschi M, Dunn MJ) Clin Sci (Lond) 2002 Aug;103 Suppl 48:132S-136S 13 Citations |
| 1 | Reduced focal adhesion kinase and paxillin phosphorylation in BCR-ABL-transfected cells. (Cheng K, Kurzrock R, Qiu X, Estrov Z, Ku S, Dulski KM, Wang JY, Talpaz M) Cancer 2002 Jul 15;95(2):440-50 23 Citations |
| 1 | Intracellular trafficking and membrane targeting mechanisms of the human reduced folate carrier in Mammalian epithelial cells. (Marchant JS, Subramanian VS, Parker I, Said HM) J Biol Chem 2002 Sep 06;277(36):33325-33 39 Citations |
| 1 | The activation of Rac1 by M3 muscarinic acetylcholine receptors involves the translocation of Rac1 and IQGAP1 to cell junctions and changes in the composition of protein complexes containing Rac1, IQGAP1, and actin. (Ruiz-Velasco R, Lanning CC, Williams CL) J Biol Chem 2002 Sep 06;277(36):33081-91 21 Citations |
| 1 | Involvement of the muscarinic acetylcholine receptor in inhibition of cell migration. (Varker KA, Williams CL) Biochem Pharmacol 2002 Feb 15;63(4):597-605 8 Citations |
| 1 | Differential regulation of gene expression by PITX2 isoforms. (Cox CJ, Espinoza HM, McWilliams B, Chappell K, Morton L, Hjalt TA, Semina EV, Amendt BA) J Biol Chem 2002 Jul 12;277(28):25001-10 141 Citations |
| 1 | Autocrine interleukin-6 production in renal cell carcinoma: evidence for the involvement of p53. (Angelo LS, Talpaz M, Kurzrock R) Cancer Res 2002 Feb 01;62(3):932-40 88 Citations |
| 1 | The 5-HT3 subtype of serotonin receptor contributes to nociceptive processing via a novel subset of myelinated and unmyelinated nociceptors. (Zeitz KP, Guy N, Malmberg AB, Dirajlal S, Martin WJ, Sun L, Bonhaus DW, Stucky CL, Julius D, Basbaum AI) J Neurosci 2002 Feb 01;22(3):1010-9 332 Citations |
| 1 | Endostatin causes G1 arrest of endothelial cells through inhibition of cyclin D1. (Hanai J, Dhanabal M, Karumanchi SA, Albanese C, Waterman M, Chan B, Ramchandran R, Pestell R, Sukhatme VP) J Biol Chem 2002 May 10;277(19):16464-9 223 Citations |
| 1 | Basolateral sorting signal of the 300-kDa mannose 6-phosphate receptor. (Wick DA, Seetharam B, Dahms NM) Am J Physiol Gastrointest Liver Physiol 2002 Jan;282(1):G51-60 10 Citations |
| 1 | Reduced expression of Wnt-1 and E-cadherin, and diminished beta-catenin stability in MCF-7 breast cancer cells that overexpress protein kinase C-alpha. (Williams CL, Noti JD) Int J Oncol 2001 Dec;19(6):1227-33 7 Citations |
| 1 | Intracellular trafficking/membrane targeting of human reduced folate carrier expressed in Xenopus oocytes. (Subramanian VS, Marchant JS, Parker I, Said HM) Am J Physiol Gastrointest Liver Physiol 2001 Dec;281(6):G1477-86 28 Citations |
| 2 | Hyperresistance to cholesterol hydroperoxide-induced peroxidative injury and apoptotic death in a tumor cell line that overexpresses glutathione peroxidase isotype-4. (Hurst R, Korytowski W, Kriska T, Esworthy RS, Chu FF, Girotti AW) Free Radic Biol Med 2001 Nov 01;31(9):1051-65 64 Citations |
| 1 | PU.1/Spi-B regulation of c-rel is essential for mature B cell survival. (Hu CJ, Rao S, Ramirez-Bergeron DL, Garrett-Sinha LA, Gerondakis S, Clark MR, Simon MC) Immunity 2001 Oct;15(4):545-55 42 Citations |
| 1 | NF-Y antagonizes renin enhancer function by blocking stimulatory transcription factors. (Shi Q, Gross KW, Sigmund CD) Hypertension 2001 Sep;38(3):332-6 33 Citations |
| 1 | Myc requires distinct E2F activities to induce S phase and apoptosis. (Leone G, Sears R, Huang E, Rempel R, Nuckolls F, Park CH, Giangrande P, Wu L, Saavedra HI, Field SJ, Thompson MA, Yang H, Fujiwara Y, Greenberg ME, Orkin S, Smith C, Nevins JR) Mol Cell 2001 Jul;8(1):105-13 219 Citations |
| 1 | Disrupted bile acid homeostasis reveals an unexpected interaction among nuclear hormone receptors, transporters, and cytochrome P450. (Schuetz EG, Strom S, Yasuda K, Lecureur V, Assem M, Brimer C, Lamba J, Kim RB, Ramachandran V, Komoroski BJ, Venkataramanan R, Cai H, Sinal CJ, Gonzalez FJ, Schuetz JD) J Biol Chem 2001 Oct 19;276(42):39411-8 363 Citations |
| 1 | HIF-1alpha binding to VHL is regulated by stimulus-sensitive proline hydroxylation. (Yu F, White SB, Zhao Q, Lee FS) Proc Natl Acad Sci U S A 2001 Aug 14;98(17):9630-5 717 Citations |
| 1 | Localization of N-terminal sequences in human AMP deaminase isoforms that influence contractile protein binding. (Mahnke-Zizelman DK, Sabina RL) Biochem Biophys Res Commun 2001 Jul 13;285(2):489-95 21 Citations |
| 1 | PreproEndothelin-1 expression in human mesangial cells: evidence for a p38 mitogen-activated protein kinase/protein kinases-C-dependent mechanism. (Foschi M, Sorokin A, Pratt P, McGinty A, Villa G, Franchi F, Dunn MJ) J Am Soc Nephrol 2001 Jun;12(6):1137-1150 19 Citations |
| 1 | Dynamic, site-specific interaction of hypoxia-inducible factor-1alpha with the von Hippel-Lindau tumor suppressor protein. (Yu F, White SB, Zhao Q, Lee FS) Cancer Res 2001 May 15;61(10):4136-42 81 Citations |
| 1 | Characterisation of Wnt gene expression during the differentiation of murine embryonic stem cells in vitro: role of Wnt3 in enhancing haematopoietic differentiation. (Lako M, Lindsay S, Lincoln J, Cairns PM, Armstrong L, Hole N) Mech Dev 2001 May;103(1-2):49-59 70 Citations |
| 2 | Inhibition of antigen-receptor signaling by Platelet Endothelial Cell Adhesion Molecule-1 (CD31) requires functional ITIMs, SHP-2, and p56(lck). (Newman DK, Hamilton C, Newman PJ) Blood 2001 Apr 15;97(8):2351-7 118 Citations |
| 1 | Protein-tyrosine kinase Pyk2 mediates endothelin-induced p38 MAPK activation in glomerular mesangial cells. (Sorokin A, Kozlowski P, Graves L, Philip A) J Biol Chem 2001 Jun 15;276(24):21521-8 65 Citations |
| 1 | Transient ectopic expression of PTEN in thyroid cancer cell lines induces cell cycle arrest and cell type-dependent cell death. (Weng LP, Gimm O, Kum JB, Smith WM, Zhou XP, Wynford-Thomas D, Leone G, Eng C) Hum Mol Genet 2001 Feb 01;10(3):251-8 82 Citations |
| 1 | Platelet activation by a relapsing fever spirochaete results in enhanced bacterium-platelet interaction via integrin alphaIIbbeta3 activation. (Alugupalli KR, Michelson AD, Barnard MR, Robbins D, Coburn J, Baker EK, Ginsberg MH, Schwan TG, Leong JM) Mol Microbiol 2001 Jan;39(2):330-40 42 Citations |
| 1 | The cellular uptake of anandamide is coupled to its breakdown by fatty-acid amide hydrolase. (Deutsch DG, Glaser ST, Howell JM, Kunz JS, Puffenbarger RA, Hillard CJ, Abumrad N) J Biol Chem 2001 Mar 09;276(10):6967-73 199 Citations |
| 1 | Identification of CD8+ T-cell-stimulating antigen genes in cDNA libraries. (Mendoza LM, Malarkannan S, Shastri N) Methods Mol Biol 2001;156:255-63 3 Citations |
| 1 | Retinoic acid-mediated activation of the mouse renin enhancer. (Shi Q, Gross KW, Sigmund CD) J Biol Chem 2001 Feb 02;276(5):3597-603 59 Citations |
| 1 | Adenovirus E1A oncogene expression in tumor cells enhances killing by TNF-related apoptosis-inducing ligand (TRAIL). (Routes JM, Ryan S, Clase A, Miura T, Kuhl A, Potter TA, Cook JL) J Immunol 2000 Oct 15;165(8):4522-7 65 Citations |
| 1 | P2Y2 purinergic and M3 muscarinic acetylcholine receptors activate different phospholipase C-beta isoforms that are uniquely susceptible to protein kinase C-dependent phosphorylation and inactivation. (Strassheim D, Williams CL) J Biol Chem 2000 Dec 15;275(50):39767-72 53 Citations |
| 1 | Pseudomonas aeruginosa ExoT is a Rho GTPase-activating protein. (Krall R, Schmidt G, Aktories K, Barbieri JT) Infect Immun 2000 Oct;68(10):6066-8 143 Citations |
| 1 | The p38 pathway provides negative feedback for Ras proliferative signaling. (Chen G, Hitomi M, Han J, Stacey DW) J Biol Chem 2000 Dec 15;275(50):38973-80 162 Citations |
| 1 | A (GATA)(7) motif located in the 5' boundary area of the human beta-globin locus control region exhibits silencer activity in erythroid cells. (Ramchandran R, Bengra C, Whitney B, Lanclos K, Tuan D) Am J Hematol 2000 Sep;65(1):14-24 18 Citations |
| 2 | Megakaryocyte-targeted synthesis of the integrin beta(3)-subunit results in the phenotypic correction of Glanzmann thrombasthenia. (Wilcox DA, Olsen JC, Ishizawa L, Bray PF, French DL, Steeber DA, Bell WR, Griffith M, White GC 2nd) Blood 2000 Jun 15;95(12):3645-51 52 Citations |
| 1 | 5-Hydroxytryptamine1A receptor/Gibetagamma stimulates mitogen-activated protein kinase via NAD(P)H oxidase and reactive oxygen species upstream of src in chinese hamster ovary fibroblasts. (Mukhin YV, Garnovskaya MN, Collinsworth G, Grewal JS, Pendergrass D, Nagai T, Pinckney S, Greene EL, Raymond JR) Biochem J 2000 Apr 01;347 Pt 1(Pt 1):61-7 68 Citations |
| 1 | Expression and function of calcium binding domain chimeras of the integrins alpha(IIb) and alpha(5). (Gidwitz S, Lyman S, White GC 2nd) J Biol Chem 2000 Mar 03;275(9):6680-8 4 Citations |
| 1 | Canstatin, a novel matrix-derived inhibitor of angiogenesis and tumor growth. (Kamphaus GD, Colorado PC, Panka DJ, Hopfer H, Ramchandran R, Torre A, Maeshima Y, Mier JW, Sukhatme VP, Kalluri R) J Biol Chem 2000 Jan 14;275(2):1209-15 433 Citations |
| 1 | Murine CCR9, a chemokine receptor for thymus-expressed chemokine that is up-regulated following pre-TCR signaling. (Norment AM, Bogatzki LY, Gantner BN, Bevan MJ) J Immunol 2000 Jan 15;164(2):639-48 95 Citations |
| 1 | Herpes simplex thymidine kinase (HStk) transgenic donor lymphocytes. (Burt RK, Drobyski WR, Traynor AE, Link CJ Jr) Bone Marrow Transplant 1999 Nov;24(10):1043-51 5 Citations |
| 1 | Calcium ionophore upregulation of AUUUA-specific binding protein activity is contemporaneous with granulocyte macrophage colony-stimulating factor messenger RNA stabilization in AML14.3D10 cells. (Ruth JH, Esnault S, Jarzembowski JA, Malter JS) Am J Respir Cell Mol Biol 1999 Nov;21(5):621-8 18 Citations |
| 1 | The recombinant 5-HT1A receptor: G protein coupling and signalling pathways. (Raymond JR, Mukhin YV, Gettys TW, Garnovskaya MN) Br J Pharmacol 1999 Aug;127(8):1751-64 222 Citations |
| 2 | Integrin alphaIIb promoter-targeted expression of gene products in megakaryocytes derived from retrovirus-transduced human hematopoietic cells. (Wilcox DA, Olsen JC, Ishizawa L, Griffith M, White GC 2nd) Proc Natl Acad Sci U S A 1999 Aug 17;96(17):9654-9 52 Citations |
| 1 | Pseudomonas aeruginosa exoenzyme S disrupts Ras-mediated signal transduction by inhibiting guanine nucleotide exchange factor-catalyzed nucleotide exchange. (Ganesan AK, Vincent TS, Olson JC, Barbieri JT) J Biol Chem 1999 Jul 30;274(31):21823-9 72 Citations |
| 1 | Presentation of out-of-frame peptide/MHC class I complexes by a novel translation initiation mechanism. (Malarkannan S, Horng T, Shih PP, Schwab S, Shastri N) Immunity 1999 Jun;10(6):681-90 94 Citations |
| 1 | Enzymatic and functional correction along with long-term enzyme secretion from transduced bone marrow hematopoietic stem/progenitor and stromal cells derived from patients with Fabry disease. (Takenaka T, Hendrickson CS, Tworek DM, Tudor M, Schiffmann R, Brady RO, Medin JA) Exp Hematol 1999 Jul;27(7):1149-59 39 Citations |
| 1 | Overexpression of protein kinase C-alpha in MCF-7 breast cancer cells results in differential regulation and expression of alphavbeta3 and alphavbeta5. (Carey I, Williams CL, Ways DK, Noti JD) Int J Oncol 1999 Jul;15(1):127-36 22 Citations |
| 2 | Synthesis and characterization of potent and selective agonists of the neuronal cannabinoid receptor (CB1). (Hillard CJ, Manna S, Greenberg MJ, DiCamelli R, Ross RA, Stevenson LA, Murphy V, Pertwee RG, Campbell WB) J Pharmacol Exp Ther 1999 Jun;289(3):1427-33 333 Citations |
| 1 | Basic fibroblast growth factor activates serum response factor gene expression by multiple distinct signaling mechanisms. (Spencer JA, Major ML, Misra RP) Mol Cell Biol 1999 Jun;19(6):3977-88 21 Citations |
| 1 | Enrichment of transiently transfected mesangial cells by cell sorting after cotransfection with GFP. (Chen R, Greene EL, Collinsworth G, Grewal JS, Houghton O, Zeng H, Garnovskaya M, Paul RV, Raymond JR) Am J Physiol 1999 May;276(5):F777-85 19 Citations |
| 2 | The amino-terminal domain of Pseudomonas aeruginosa ExoS disrupts actin filaments via small-molecular-weight GTP-binding proteins. (Pederson KJ, Vallis AJ, Aktories K, Frank DW, Barbieri JT) Mol Microbiol 1999 Apr;32(2):393-401 123 Citations |
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| 1 | Ras enhances Myc protein stability. (Sears R, Leone G, DeGregori J, Nevins JR) Mol Cell 1999 Feb;3(2):169-79 401 Citations |
| 1 | Kidney is the only source of human plasma renin in 45-kb human renin transgenic mice. (Yan Y, Chen R, Pitarresi T, Sigmund CD, Gross KW, Sealey JE, Laragh JH, Catanzaro DF) Circ Res 1998 Dec 14-28;83(12):1279-88 27 Citations |
| 1 | Functionally active catalytic domain is essential for guanylyl cyclase-linked receptor mediated inhibition of human aldosterone synthesis. (Olson LJ, Ho BY, Cashdollar LW, Drewett JG) Mol Pharmacol 1998 Nov;54(5):761-9 10 Citations |
| 1 | An antibody from a patient with ranitidine-induced thrombocytopenia recognizes a site on glycoprotein IX that is a favored target for drug-induced antibodies. (Gentilini G, Curtis BR, Aster RH) Blood 1998 Oct 01;92(7):2359-65 51 Citations |
| 1 | The two mannose 6-phosphate binding sites of the insulin-like growth factor-II/mannose 6-phosphate receptor display different ligand binding properties. (Marron-Terada PG, Brzycki-Wessell MA, Dahms NM) J Biol Chem 1998 Aug 28;273(35):22358-66 28 Citations |
| 1 | Mutations in Drosophila enabled and rescue by human vasodilator-stimulated phosphoprotein (VASP) indicate important functional roles for Ena/VASP homology domain 1 (EVH1) and EVH2 domains. (Ahern-Djamali SM, Comer AR, Bachmann C, Kastenmeier AS, Reddy SK, Beckerle MC, Walter U, Hoffmann FM) Mol Biol Cell 1998 Aug;9(8):2157-71 96 Citations |
| 1 | The neuropeptide Y/peptide YY Y1 receptor is coupled to MAP kinase via PKC and Ras in CHO cells. (Mannon PJ, Raymond JR) Biochem Biophys Res Commun 1998 May 08;246(1):91-4 29 Citations |
| 1 | Characterization of the chimeric retinoic acid receptor RARalpha/VDR. (Pemrick SM, Abarzúa P, Kratzeisen C, Marks MS, Medin JA, Ozato K, Grippo JF) Leukemia 1998 Apr;12(4):554-62 6 Citations |
| 1 | Interleukin-1 increases expression of the LYT-10 (NFkappaB2) proto-oncogene/transcription factor in renal cell carcinoma lines. (Kurzrock R, Estrov Z, Ku S, Leonard M, Talpaz M) J Lab Clin Med 1998 Mar;131(3):261-8 5 Citations |
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| 1 | Retinoid X receptor and peroxisome proliferator-activated receptor activate an estrogen responsive gene independent of the estrogen receptor. (Nuñez SB, Medin JA, Braissant O, Kemp L, Wahli W, Ozato K, Segars JH) Mol Cell Endocrinol 1997 Mar 14;127(1):27-40 92 Citations |
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| 1 | Functional analysis of E2F transcription factor. (Nevins JR, DeGregori J, Jakoi L, Leone G) Methods Enzymol 1997;283:205-19 73 Citations |
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| 1 | The mouse mammary tumor virus env gene is the source of a CD8+ T-cell-stimulating peptide presented by a major histocompatibility complex class I molecule in a murine thymoma. (Malarkannan S, Serwold T, Nguyen V, Sherman LA, Shastri N) Proc Natl Acad Sci U S A 1996 Nov 26;93(24):13991-6 23 Citations |
| 1 | PCR-based gene targeting of the inducible nitric oxide synthase (NOS2) locus in murine ES cells, a new and more cost-effective approach. (Randolph DA, Verbsky JW, Yang L, Fang Y, Hakem R, Fields LE) Transgenic Res 1996 Nov;5(6):413-20 6 Citations |
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| 1 | Inconstant association between 27-kDa heat-shock protein (Hsp27) content and doxorubicin resistance in human colon cancer cells. The doxorubicin-protecting effect of Hsp27. (Garrido C, Mehlen P, Fromentin A, Hammann A, Assem M, Arrigo AP, Chauffert B) Eur J Biochem 1996 May 01;237(3):653-9 79 Citations |
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| 1 | A bicistronic therapeutic retroviral vector enables sorting of transduced CD34+ cells and corrects the enzyme deficiency in cells from Gaucher patients. (Medin JA, Migita M, Pawliuk R, Jacobson S, Amiri M, Kluepfel-Stahl S, Brady RO, Humphries RK, Karlsson S) Blood 1996 Mar 01;87(5):1754-62 39 Citations |
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| 1 | E1A gene expression induces susceptibility to killing by NK cells following immortalization but not adenovirus infection of human cells. (Routes JM, Cook JL) Virology 1995 Jul 10;210(2):421-8 27 Citations |
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| 1 | Regulation of allergic contact sensitivity in mice: soluble alpha beta T cell receptors, derived via cDNA transfection and enzymatic cleavage from the surface of T cells, protect contact sensitivity effector T cells from active T cell suppression. (Paliwal V, Ptak W, Askenase PW) Int Arch Allergy Immunol 1995;107(1-3):365 1 Citation |
| 1 | Functional interactions between the retinoblastoma (Rb) protein and Sp-family members: superactivation by Rb requires amino acids necessary for growth suppression. (Udvadia AJ, Templeton DJ, Horowitz JM) Proc Natl Acad Sci U S A 1995 Apr 25;92(9):3953-7 200 Citations |
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