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Cecilia J. Hillard PhD

Cecilia J. Hillard PhD profile photo picture

Associate Dean, Center Director, Professor

Institution: Medical College of Wisconsin
Department: Pharmacology and Toxicology
Program: Pharmacology

Director of the Neuroscience Research Center
Member of the Cancer Center
Member of the Center for Disease Prevention Research (CDPR)
Member of the Center for Immunology
Member of the Comprehensive Injury Center

View Curriculum Vitae

Research Experience

  • Anxiety
  • Brain
  • Cannabidiol
  • Cannabinoid Receptor Agonists
  • Cannabinoid Receptor Modulators
  • Cannabinoids
  • Carrier Proteins
  • Cells, Cultured
  • Cocaine
  • Corticosterone
  • Depression
  • Endocannabinoids
  • Mice
  • Microglia
  • Models, Animal
  • Neurons
  • Obesity
  • Rats, Sprague-Dawley
  • Receptor, Cannabinoid, CB1
  • Receptor, Cannabinoid, CB2
  • Receptors, Cannabinoid
  • Receptors, Drug
  • Restraint, Physical
  • Signal Transduction
  • Stress, Physiological
  • Stress, Psychological

  • Publications (290)

  • Dysfunction in endocannabinoids, palmitoylethanolamide, and degradation of tryptophan into kynurenine in individuals with depressive symptoms. (Comai S, Nunez N, Atkin T, Ghabrash MF, Zakarian R, Fielding A, Saint-Laurent M, Low N, Sauber G, Ragazzi E, Hillard CJ, Gobbi G) BMC Med 2024 Jan 25;22(1):33 PMID: 38273283 PMCID: PMC10809514 SCOPUS ID: 2-s2.0-85182980042 01/26/2024    
  • Effect of trauma type and trauma burden on self-efficacy for physical exercise in military veterans (Davis KE, Bennett MM, Hillard CJ, Whittle J, Franco Z, Bollaert RE, Fitzgerald JM) Trauma (United Kingdom) 2024 SCOPUS ID: 2-s2.0-85186393424 01/01/2024    
  • Endocannabinoid and psychological responses to acute resistance exercise in trained and untrained adults. (Sirotiak Z, Gallagher BT, Smith-Hernandez CA, Showman LJ, Hillard CJ, Brellenthin AG) PLoS One 2023;18(12):e0291845 PMID: 38039265 PMCID: PMC10691681 SCOPUS ID: 2-s2.0-85178330078 12/01/2023    
  • Endocannabinoids, cortisol, and development of post-traumatic psychopathological trajectories. (Jayan D, Timmer-Murillo S, Fitzgerald JM, Hillard CJ, de Roon-Cassini TA) Gen Hosp Psychiatry 2023;85:199-206 PMID: 37956620 PMCID: PMC10843734 SCOPUS ID: 2-s2.0-85176356508 11/14/2023    
  • The endocannabinoid system as a putative target for the development of novel drugs for the treatment of psychiatric illnesses. (Hill MN, Haney M, Hillard CJ, Karhson DS, Vecchiarelli HA) Psychol Med 2023 Nov;53(15):7006-7024 PMID: 37671673 PMCID: PMC10719691 SCOPUS ID: 2-s2.0-85170686532 09/06/2023       1 Citation
  • MICROGLIAL CELL EXPRESSION OF THE TYPE 2 CANNABINOID RECEPTOR REGULATES IMMUNE-MEDIATED NEUROINFLAMMATION. (Moe A, Rayasam A, Sauber G, Shah RK, Yuan CY, Szabo A, Moore BM, Colonna M, Cui W, Romero J, Zamora AE, Hillard CJ, Drobyski WR) bioRxiv 2023 Aug 14 PMID: 37645843 PMCID: PMC10462026 08/30/2023    
  • Conditional deletion of CB2 cannabinoid receptors from peripheral sensory neurons eliminates CB2-mediated antinociceptive efficacy in a mouse model of carrageenan-induced inflammatory pain. (Guenther KG, Xu Z, Romero J, Hillard CJ, Mackie K, Hohmann AG) Neuropharmacology 2023 Oct 01;237:109601 PMID: 37286073 PMCID: PMC10409300 SCOPUS ID: 2-s2.0-85161662256 06/08/2023       2 Citations
  • Role of mesolimbic cannabinoid receptor 1 in stress-driven increases in cocaine self-administration in male rats. (McReynolds JR, Wolf CP, Starck DM, Mathy JC, Schaps R, Krause LA, Hillard CJ, Mantsch JR) Neuropsychopharmacology 2023 Jul;48(8):1121-1132 PMID: 37188846 PMCID: PMC10267161 SCOPUS ID: 2-s2.0-85159362811 05/16/2023       2 Citations
  • Circulating endocannabinoids and psychological outcomes in women with PTSD (Botsford C, Brellenthin AG, Cisler JM, Hillard CJ, Koltyn KF, Crombie KM) Journal of Anxiety Disorders January 2023;93 SCOPUS ID: 2-s2.0-85143352081 01/01/2023       3 Citations
  • FAAH Inhibition Restores Early Life Stress-Induced Alterations in PFC microRNAs Associated with Depressive-Like Behavior in Male and Female Rats. (Portugalov A, Zaidan H, Gaisler-Salomon I, Hillard CJ, Akirav I) Int J Mol Sci 2022 Dec 17;23(24) PMID: 36555739 PMCID: PMC9782513 SCOPUS ID: 2-s2.0-85144537750 12/24/2022       5 Citations
  • Circulating endocannabinoids and psychological outcomes in women with PTSD. (Botsford C, Brellenthin AG, Cisler JM, Hillard CJ, Koltyn KF, Crombie KM) J Anxiety Disord 2023 Jan;93:102656 PMID: 36469982 PMCID: PMC9839585 SCOPUS ID: 2-s2.0-85143352081 12/06/2022       3 Citations
  • Altered glial expression of the cannabinoid 1 receptor in the subiculum of a mouse model of Alzheimer's disease. (Terradillos I, Bonilla-Del Río I, Puente N, Serrano M, Mimenza A, Lekunberri L, Anaut-Lusar I, Reguero L, Gerrikagoitia I, Ruiz de Martín Esteban S, Hillard CJ, Grande MT, Romero J, Elezgarai I, Grandes P) Glia 2023 Apr;71(4):866-879 PMID: 36437738 SCOPUS ID: 2-s2.0-85142903688 11/29/2022       2 Citations
  • Peripheral sensory neuron CB2 cannabinoid receptors are necessary for both CB2-mediated antinociceptive efficacy and sparing of morphine tolerance in a mouse model of anti-retroviral toxic neuropathy. (Carey LM, Xu Z, Rajic G, Makriyannis A, Romero J, Hillard C, Mackie K, Hohmann AG) Pharmacol Res 2023 Jan;187:106560 PMID: 36417942 PMCID: PMC9845180 SCOPUS ID: 2-s2.0-85142686286 11/24/2022       7 Citations
  • Endocannabinoid signaling in the central nervous system. (Martinez Ramirez CE, Ruiz-Pérez G, Stollenwerk TM, Behlke C, Doherty A, Hillard CJ) Glia 2023 Jan;71(1):5-35 PMID: 36308424 PMCID: PMC10167744 SCOPUS ID: 2-s2.0-85141398970 10/30/2022       5 Citations
  • Editorial: Therapeutic potential of the cannabinoid CB2 receptor. (Smoum R, Grether U, Karsak M, Vernall AJ, Park F, Hillard CJ, Pacher P) Front Pharmacol 2022;13:1039564 PMID: 36278235 PMCID: PMC9585503 SCOPUS ID: 2-s2.0-85140462458 10/25/2022       1 Citation
  • Associations between socioeconomic status and bispecific LV20.19 CAR T-cell therapy outcomes. (Knight JM, Hackett E, Szabo A, Wu R, Sauber G, Johnson B, Cusatis RN, Aughey E, Cole SW, Hillard CJ, Shah NN) Haematologica 2023 Feb 01;108(2):588-593 PMID: 36200427 PMCID: PMC9890001 SCOPUS ID: 2-s2.0-85147234722 10/07/2022       1 Citation
  • Editorial: Therapeutic potential of the cannabinoid CB2 receptor (Smoum R, Grether U, Karsak M, Vernall AJ, Park F, Hillard CJ, Pacher P) Frontiers in Pharmacology 7 October 2022;13 SCOPUS ID: 2-s2.0-85140462458 10/07/2022       1 Citation
  • Fatty acid amide hydrolase activity in the dorsal periaqueductal gray attenuates neuropathic pain and associated dysautonomia. (Woyach V, Sherman K, Hillard CJ, Hopp FA, Hogan QH, Dean C) Am J Physiol Regul Integr Comp Physiol 2022 Nov 01;323(5):R749-R762 PMID: 36154489 PMCID: PMC9639763 SCOPUS ID: 2-s2.0-85141004185 09/27/2022    
  • Machine learning prediction of posttraumatic stress disorder trajectories following traumatic injury: Identification and validation in two independent samples. (Tomas CW, Fitzgerald JM, Bergner C, Hillard CJ, Larson CL, deRoon-Cassini TA) J Trauma Stress 2022 Dec;35(6):1656-1671 PMID: 36006041 SCOPUS ID: 2-s2.0-85136599889 08/26/2022       3 Citations
  • The influence of depression on the relationship between loneliness and grief trajectories in bereaved older adults. (Reiland H, Banerjee A, Claesges SA, Giuca AM, Hillard CJ, Reynolds CF 3rd, Goveas JS) Psychiatry Res Commun 2021 Oct;1(1) PMID: 35928209 PMCID: PMC9345326 SCOPUS ID: 2-s2.0-85133781725 08/06/2022       5 Citations
  • CB2 Agonist GW842166x Protected against 6-OHDA-Induced Anxiogenic- and Depressive-Related Behaviors in Mice. (Liu X, Yu H, Chen B, Friedman V, Mu L, Kelly TJ, Ruiz-Pérez G, Zhao L, Bai X, Hillard CJ, Liu QS) Biomedicines 2022 Jul 22;10(8) PMID: 35892676 PMCID: PMC9329798 SCOPUS ID: 2-s2.0-85137365256 07/28/2022       6 Citations
  • Serum Concentrations of the Endocannabinoid, 2-Arachidonoylglycerol, in the Peri-Trauma Period Are Positively Associated with Chronic Pain Months Later. (Trevino CM, Hillard CJ, Szabo A, deRoon-Cassini TA) Biomedicines 2022 Jul 05;10(7) PMID: 35884902 PMCID: PMC9313032 SCOPUS ID: 2-s2.0-85133855475 07/28/2022       1 Citation
  • Serum Concentrations of the Endocannabinoid, 2-Arachidonoylglycerol, in the Peri-Trauma Period Are Positively Associated with Chronic Pain Months Later (Trevino CM, Hillard CJ, Szabo A, Deroon-Cassini TA) Biomedicines July 2022;10(7) SCOPUS ID: 2-s2.0-85133855475 07/01/2022       1 Citation
  • The effect of tocilizumab on patient reported outcomes and inflammatory biomarkers in hematopoietic cell transplantation. (Taylor MR, Hillard CJ, Drobyski WR, Szabo A, Johnson BD, Zhu F, Raison CL, Cole SW, Knight JM) Brain Behav Immun Health 2022 Aug;23:100480 PMID: 35757656 PMCID: PMC9213229 SCOPUS ID: 2-s2.0-85133379996 06/28/2022       2 Citations
  • Detection of cannabinoid receptor type 2 in native cells and zebrafish with a highly potent, cell-permeable fluorescent probe. (Gazzi T, Brennecke B, Atz K, Korn C, Sykes D, Forn-Cuni G, Pfaff P, Sarott RC, Westphal MV, Mostinski Y, Mach L, Wasinska-Kalwa M, Weise M, Hoare BL, Miljuš T, Mexi M, Roth N, Koers EJ, Guba W, Alker A, Rufer AC, Kusznir EA, Huber S, Raposo C, Zirwes EA, Osterwald A, Pavlovic A, Moes S, Beck J, Nettekoven M, Benito-Cuesta I, Grande T, Drawnel F, Widmer G, Holzer D, van der Wel T, Mandhair H, Honer M, Fingerle J, Scheffel J, Broichhagen J, Gawrisch K, Romero J, Hillard CJ, Varga ZV, van der Stelt M, Pacher P, Gertsch J, Ullmer C, McCormick PJ, Oddi S, Spaink HP, Maccarrone M, Veprintsev DB, Carreira EM, Grether U, Nazaré M) Chem Sci 2022 May 18;13(19):5539-5545 PMID: 35694350 PMCID: PMC9116301 SCOPUS ID: 2-s2.0-85132587227 06/14/2022       11 Citations
  • Cannabinoid CB2 Receptors Modulate Microglia Function and Amyloid Dynamics in a Mouse Model of Alzheimer's Disease. (Ruiz de Martín Esteban S, Benito-Cuesta I, Terradillos I, Martínez-Relimpio AM, Arnanz MA, Ruiz-Pérez G, Korn C, Raposo C, Sarott RC, Westphal MV, Elezgarai I, Carreira EM, Hillard CJ, Grether U, Grandes P, Grande MT, Romero J) Front Pharmacol 2022;13:841766 PMID: 35645832 PMCID: PMC9136843 SCOPUS ID: 2-s2.0-85131322351 06/02/2022       15 Citations
  • Patient-reported outcomes and neurotoxicity markers in patients treated with bispecific LV20.19 CAR T cell therapy. (Knight JM, Szabo A, Arapi I, Wu R, Emmrich A, Hackett E, Sauber G, Yim S, Johnson B, Hari P, Schneider D, Dropulic B, Cusatis RN, Cole SW, Hillard CJ, Shah NN) Commun Med (Lond) 2022;2(1):49 PMID: 35603278 PMCID: PMC9098435 05/24/2022    
  • Amygdalar CB2 cannabinoid receptor mediates fear extinction deficits promoted by orexin-A/hypocretin-1 (Ten-Blanco M, Flores Á, Pereda-Pérez I, Piscitelli F, Izquierdo-Luengo C, Cristino L, Romero J, Hillard CJ, Maldonado R, Di Marzo V, Berrendero F) Biomedicine and Pharmacotherapy May 2022;149 SCOPUS ID: 2-s2.0-85127815071 05/01/2022       11 Citations
  • Amygdalar CB2 cannabinoid receptor mediates fear extinction deficits promoted by orexin-A/hypocretin-1. (Ten-Blanco M, Flores Á, Pereda-Pérez I, Piscitelli F, Izquierdo-Luengo C, Cristino L, Romero J, Hillard CJ, Maldonado R, Di Marzo V, Berrendero F) Biomed Pharmacother 2022 May;149:112925 PMID: 35477218 SCOPUS ID: 2-s2.0-85127815071 04/29/2022       11 Citations
  • Cannabinoid CB2 Receptors Modulate Microglia Function and Amyloid Dynamics in a Mouse Model of Alzheimer’s Disease (Ruiz de Martín Esteban S, Benito-Cuesta I, Terradillos I, Martínez-Relimpio AM, Arnanz MA, Ruiz-Pérez G, Korn C, Raposo C, Sarott RC, Westphal MV, Elezgarai I, Carreira EM, Hillard CJ, Grether U, Grandes P, Grande MT, Romero J) Frontiers in Pharmacology 27 April 2022;13 SCOPUS ID: 2-s2.0-85131322351 04/27/2022       15 Citations
  • Circulating endocannabinoids and genetic polymorphisms as predictors of posttraumatic stress disorder symptom severity: heterogeneity in a community-based cohort. (deRoon-Cassini TA, Bergner CL, Chesney SA, Schumann NR, Lee TS, Brasel KJ, Hillard CJ) Transl Psychiatry 2022 Feb 01;12(1):48 PMID: 35105857 PMCID: PMC8807700 SCOPUS ID: 2-s2.0-85124060615 02/03/2022       15 Citations
  • A peripheral CB2 cannabinoid receptor mechanism suppresses chemotherapy-induced peripheral neuropathy: evidence from a CB2 reporter mouse. (Lin X, Xu Z, Carey L, Romero J, Makriyannis A, Hillard CJ, Ruggiero E, Dockum M, Houk G, Mackie K, Albrecht PJ, Rice FL, Hohmann AG) Pain 2022 May 01;163(5):834-851 PMID: 35001054 PMCID: PMC8942871 SCOPUS ID: 2-s2.0-85128493394 01/11/2022       14 Citations
  • Detection of cannabinoid receptor type 2 in native cells and zebrafish with a highly potent, cell-permeable fluorescent probe (Gazzi T, Brennecke B, Atz K, Korn C, Sykes D, Forn-Cuni G, Pfaff P, Sarott RC, Westphal MV, Mostinski Y, Mach L, Wasinska-Kalwa M, Weise M, Hoare BL, Miljuš T, Mexi M, Roth N, Koers EJ, Guba W, Alker A, Rufer AC, Kusznir EA, Huber S, Raposo C, Zirwes EA, Osterwald A, Pavlovic A, Moes S, Beck J, Nettekoven M, Benito-Cuesta I, Grande T, Drawnel F, Widmer G, Holzer D, van der Wel T, Mandhair H, Honer M, Fingerle J, Scheffel J, Broichhagen J, Gawrisch K, Romero J, Hillard CJ, Varga ZV, van der Stelt M, Pacher P, Gertsch J, Ullmer C, McCormick PJ, Oddi S, Spaink HP, Maccarrone M, Veprintsev DB, Carreira EM, Grether U, Nazaré M) Chemical Science 2022 SCOPUS ID: 2-s2.0-85132587227 01/01/2022       11 Citations
  • Loneliness, Circulating Endocannabinoid Concentrations, and Grief Trajectories in Bereaved Older Adults: A Longitudinal Study. (Kang M, Bohorquez-Montoya L, McAuliffe T, Claesges SA, Blair NO, Sauber G, Reynolds CF 3rd, Hillard CJ, Goveas JS) Front Psychiatry 2021;12:783187 PMID: 34955928 PMCID: PMC8692767 SCOPUS ID: 2-s2.0-85121649643 12/28/2021       3 Citations
  • The Neuroprotective Effects of the CB2 Agonist GW842166x in the 6-OHDA Mouse Model of Parkinson's Disease. (Yu H, Liu X, Chen B, Vickstrom CR, Friedman V, Kelly TJ, Bai X, Zhao L, Hillard CJ, Liu QS) Cells 2021 Dec 16;10(12) PMID: 34944056 PMCID: PMC8700250 SCOPUS ID: 2-s2.0-85121121427 12/25/2021       14 Citations
  • Adolescent THC Treatment Does Not Potentiate the Behavioral Effects in Adulthood of Maternal Immune Activation. (Stollenwerk TM, Hillard CJ) Cells 2021 Dec 11;10(12) PMID: 34944011 PMCID: PMC8700174 SCOPUS ID: 2-s2.0-85121034066 12/25/2021       7 Citations
  • Adolescent thc treatment does not potentiate the behavioral effects in adulthood of maternal immune activation (Stollenwerk TM, Hillard CJ) Cells December 2021;10(12) SCOPUS ID: 2-s2.0-85121034066 12/01/2021       7 Citations
  • The neuroprotective effects of the cb2 agonist gw842166x in the 6-ohda mouse model of parkinson’s disease (Yu H, Liu X, Chen B, Vickstrom CR, Friedman V, Kelly TJ, Bai X, Zhao L, Hillard CJ, Liu QS) Cells December 2021;10(12) SCOPUS ID: 2-s2.0-85121121427 12/01/2021       14 Citations
  • A cluster analytic approach to examining the role of cortisol in the development of post-traumatic stress and dysphoria in adult traumatic injury survivors. (Jayan D, deRoon-Cassini TA, Sauber G, Hillard CJ, Fitzgerald JM) Psychoneuroendocrinology 2022 Jan;135:105450 PMID: 34775251 PMCID: PMC8686692 SCOPUS ID: 2-s2.0-85118826291 11/15/2021       3 Citations
  • Exercise-induced increases in Anandamide and BDNF during extinction consolidation contribute to reduced threat following reinstatement: Preliminary evidence from a randomized controlled trial (Crombie KM, Sartin-Tarm A, Sellnow K, Ahrenholtz R, Lee S, Matalamaki M, Almassi NE, Hillard CJ, Koltyn KF, Adams TG, Cisler JM) Psychoneuroendocrinology October 2021;132 SCOPUS ID: 2-s2.0-85110337155 10/01/2021       18 Citations
  • The MSDB sends a GABAergic projection to cholinergic neurons in the ventral MHb (Casey R. Vickstrom, Xiaojie Liu, Shuai Liu, Meng-Ming Hu, Lianwei Mu, Ying Hu, Hao Yu, Santidra L. Love, Cecilia J. Hillard, Qing-song Liu ) Molecular Psychiatry Vickstrom, C.R., Liu, X., Liu, S. et al. The MSDB sends a GABAergic projection to cholinergic neurons in the ventral MHb. Mol Psychiatry 26, 2679 (2021). https://doi.org/10.1038/s41380-021-01280-1 09/15/2021    
  • Contribution of the Adenosine 2A Receptor to Behavioral Effects of Tetrahydrocannabinol, Cannabidiol and PECS-101. (Stollenwerk TM, Pollock S, Hillard CJ) Molecules 2021 Sep 02;26(17) PMID: 34500787 PMCID: PMC8434367 SCOPUS ID: 2-s2.0-85114348357 09/11/2021       6 Citations
  • Contribution of the adenosine 2a receptor to behavioral effects of tetrahydrocannabinol, cannabidiol and pecs‐101 (Stollenwerk TM, Pollock S, Hillard CJ) Molecules September 2021;26(17) SCOPUS ID: 2-s2.0-85114348357 09/01/2021       6 Citations
  • Exercise-induced increases in Anandamide and BDNF during extinction consolidation contribute to reduced threat following reinstatement: Preliminary evidence from a randomized controlled trial. (Crombie KM, Sartin-Tarm A, Sellnow K, Ahrenholtz R, Lee S, Matalamaki M, Almassi NE, Hillard CJ, Koltyn KF, Adams TG, Cisler JM) Psychoneuroendocrinology 2021 Oct;132:105355 PMID: 34280820 PMCID: PMC8487992 SCOPUS ID: 2-s2.0-85110337155 07/20/2021       18 Citations
  • Dynamic Change of Endocannabinoid Signaling in the Medial Prefrontal Cortex Controls the Development of Depression After Neuropathic Pain. (Mecca CM, Chao D, Yu G, Feng Y, Segel I, Zhang Z, Rodriguez-Garcia DM, Pawela CP, Hillard CJ, Hogan QH, Pan B) J Neurosci 2021 Sep 01;41(35):7492-7508 PMID: 34244365 PMCID: PMC8412994 SCOPUS ID: 2-s2.0-85114152937 07/11/2021       20 Citations
  • The MSDB sends a GABAergic projection to cholinergic neurons in the ventral MHb (Vickstrom CR, Liu X, Liu S, Hu MM, Mu L, Hu Y, Yu H, Love SL, Hillard CJ, Liu Qs) Molecular Psychiatry July 2021;26(7):2679 SCOPUS ID: 2-s2.0-85116774276 07/01/2021    
  • Aerobic exercise reduces anxiety and fear ratings to threat and increases circulating endocannabinoids in women with and without PTSD. (Crombie KM, Cisler JM, Hillard CJ, Koltyn KF) Ment Health Phys Act 2021 Mar;20 PMID: 34149867 PMCID: PMC8208522 SCOPUS ID: 2-s2.0-85096184341 06/22/2021       17 Citations
  • Inactivation of the CB2 receptor accelerated the neuropathological deterioration in TDP-43 transgenic mice, a model of amyotrophic lateral sclerosis. (Rodríguez-Cueto C, Gómez-Almería M, García Toscano L, Romero J, Hillard CJ, de Lago E, Fernández-Ruiz J) Brain Pathol 2021 Nov;31(6):e12972 PMID: 33983653 PMCID: PMC8549023 SCOPUS ID: 2-s2.0-85105617074 05/14/2021       13 Citations
  • Circulating endocannabinoids and prospective risk for depression in trauma-injury survivors (Fitzgerald JM, Chesney SA, Lee TS, Brasel K, Larson CL, Hillard CJ, deRoon-Cassini TA) Neurobiology of Stress May 2021;14 SCOPUS ID: 2-s2.0-85100474357 05/01/2021       15 Citations
  • Aerobic exercise reduces anxiety and fear ratings to threat and increases circulating endocannabinoids in women with and without PTSD (Crombie KM, Cisler JM, Hillard CJ, Koltyn KF) Mental Health and Physical Activity March 2021;20 SCOPUS ID: 2-s2.0-85096184341 03/01/2021       17 Citations
  • Circulating endocannabinoids and prospective risk for depression in trauma-injury survivors. (Fitzgerald JM, Chesney SA, Lee TS, Brasel K, Larson CL, Hillard CJ, deRoon-Cassini TA) Neurobiol Stress 2021 May;14:100304 PMID: 33614866 PMCID: PMC7876629 SCOPUS ID: 2-s2.0-85100474357 02/23/2021       15 Citations
  • Inhibition of Fatty Acid Amide Hydrolase (FAAH) During Adolescence and Exposure to Early Life Stress may Exacerbate Depression-like Behaviors in Male and Female Rats (Alteba S, Portugalov A, Hillard CJ, Akirav I) Neuroscience 10 February 2021;455:89-106 SCOPUS ID: 2-s2.0-85098975643 02/10/2021       12 Citations
  • The IL-6 antagonist tocilizumab is associated with worse depression and related symptoms in the medically ill. (Knight JM, Costanzo ES, Singh S, Yin Z, Szabo A, Pawar DS, Hillard CJ, Rizzo JD, D'Souza A, Pasquini M, Coe CL, Irwin MR, Raison CL, Drobyski WR) Transl Psychiatry 2021 Jan 18;11(1):58 PMID: 33462203 PMCID: PMC7812704 SCOPUS ID: 2-s2.0-85100097244 01/20/2021       36 Citations
  • Inhibition of Fatty Acid Amide Hydrolase (FAAH) During Adolescence and Exposure to Early Life Stress may Exacerbate Depression-like Behaviors in Male and Female Rats. (Alteba S, Portugalov A, Hillard CJ, Akirav I) Neuroscience 2021 Feb 10;455:89-106 PMID: 33359656 SCOPUS ID: 2-s2.0-85098975643 12/29/2020       12 Citations
  • Peripherally restricted cannabinoid type 1 receptor (CB1R) antagonist, AM6545, potentiates stress-induced hypothalamic-pituitary-adrenal axis activation via a non-CB1R mechanism. (Roberts CJ, Hillard CJ) Endocrine 2021 Apr;72(1):297-300 PMID: 33216305 PMCID: PMC8528513 SCOPUS ID: 2-s2.0-85096389716 11/21/2020       2 Citations
  • Endocannabinoids and related lipids in serum from patients with amyotrophic lateral sclerosis. (Carter GT, McLaughlin RJ, Cuttler C, Sauber GJ, Weeks DL, Hillard CJ, Weiss MD) Muscle Nerve 2021 Jan;63(1):120-126 PMID: 33094490 SCOPUS ID: 2-s2.0-85096633541 10/24/2020       3 Citations
  • Role of endocannabinoid signaling in a septohabenular pathway in the regulation of anxiety- and depressive-like behavior. (Vickstrom CR, Liu X, Liu S, Hu MM, Mu L, Hu Y, Yu H, Love SL, Hillard CJ, Liu QS) Mol Psychiatry 2021 Jul;26(7):3178-3191 PMID: 33093652 PMCID: PMC8060365 SCOPUS ID: 2-s2.0-85093837658 10/24/2020       26 Citations
  • Signaling through the type 2 cannabinoid receptor regulates the severity of acute and chronic graft-versus-host disease. (Yuan CY, Zhou V, Sauber G, Stollenwerk T, Komorowski R, López A, Tolón RM, Romero J, Hillard CJ, Drobyski WR) Blood 2021 Mar 04;137(9):1241-1255 PMID: 33027805 PMCID: PMC7933769 SCOPUS ID: 2-s2.0-85101859000 10/08/2020       11 Citations
  • Circulating endocannabinoid concentrations in grieving adults (Harfmann EJ, McAuliffe TL, Larson ER, Claesges SA, Sauber G, Hillard CJ, Goveas JS) Psychoneuroendocrinology October 2020;120 SCOPUS ID: 2-s2.0-85087803094 10/01/2020       8 Citations
  • Antidepressant-like effects of URB597 and JZL184 in male and female rats exposed to early life stress (Alteba S, Mizrachi Zer-Aviv T, Tenenhaus A, Ben David G, Adelman J, Hillard CJ, Doron R, Akirav I) European Neuropsychopharmacology October 2020;39:70-86 SCOPUS ID: 2-s2.0-85090150762 10/01/2020       21 Citations
  • Development of High-Specificity Fluorescent Probes to Enable Cannabinoid Type 2 Receptor Studies in Living Cells. (Sarott RC, Westphal MV, Pfaff P, Korn C, Sykes DA, Gazzi T, Brennecke B, Atz K, Weise M, Mostinski Y, Hompluem P, Koers E, Miljuš T, Roth NJ, Asmelash H, Vong MC, Piovesan J, Guba W, Rufer AC, Kusznir EA, Huber S, Raposo C, Zirwes EA, Osterwald A, Pavlovic A, Moes S, Beck J, Benito-Cuesta I, Grande T, Ruiz de Martı N Esteban S, Yeliseev A, Drawnel F, Widmer G, Holzer D, van der Wel T, Mandhair H, Yuan CY, Drobyski WR, Saroz Y, Grimsey N, Honer M, Fingerle J, Gawrisch K, Romero J, Hillard CJ, Varga ZV, van der Stelt M, Pacher P, Gertsch J, McCormick PJ, Ullmer C, Oddi S, Maccarrone M, Veprintsev DB, Nazaré M, Grether U, Carreira EM) J Am Chem Soc 2020 Oct 07;142(40):16953-16964 PMID: 32902974 SCOPUS ID: 2-s2.0-85092682450 09/10/2020       31 Citations
  • Antidepressant-like effects of URB597 and JZL184 in male and female rats exposed to early life stress. (Alteba S, Mizrachi Zer-Aviv T, Tenenhaus A, Ben David G, Adelman J, Hillard CJ, Doron R, Akirav I) Eur Neuropsychopharmacol 2020 Oct;39:70-86 PMID: 32891517 SCOPUS ID: 2-s2.0-85090150762 09/07/2020       21 Citations
  • Meet Your Stress Management Professionals: The Endocannabinoids. (deRoon-Cassini TA, Stollenwerk TM, Beatka M, Hillard CJ) Trends Mol Med 2020 Oct;26(10):953-968 PMID: 32868170 PMCID: PMC7530069 SCOPUS ID: 2-s2.0-85089963030 09/02/2020       27 Citations
  • Traumatic Brain Injury and Alcohol Drinking Alter Basolateral Amygdala Endocannabinoids in Female Rats. (Stielper ZF, Fucich EA, Middleton JW, Hillard CJ, Edwards S, Molina PE, Gilpin NW) J Neurotrauma 2021 Feb 15;38(4):422-434 PMID: 32838651 PMCID: PMC7875607 SCOPUS ID: 2-s2.0-85092900013 08/26/2020       7 Citations
  • Circulating endocannabinoid concentrations in grieving adults. (Harfmann EJ, McAuliffe TL, Larson ER, Claesges SA, Sauber G, Hillard CJ, Goveas JS) Psychoneuroendocrinology 2020 Oct;120:104801 PMID: 32682172 PMCID: PMC7348598 SCOPUS ID: 2-s2.0-85087803094 07/19/2020       8 Citations
  • Hot-Water Bathing Improves Symptoms in Patients with Cyclic Vomiting Syndrome and Is Modulated by Chronic Cannabis Use. (Rosen S, Diaz R, Garacci Z, Kumar VCS, Thyarala SR, Hillard CJ, Venkatesan T) Dig Dis Sci 2021 Apr;66(4):1153-1161 PMID: 32472256 SCOPUS ID: 2-s2.0-85085560520 05/31/2020       10 Citations
  • Adverse maternal environment and western diet impairs cognitive function and alters hippocampal glucocorticoid receptor promoter methylation in male mice. (Ke X, Fu Q, Sterrett J, Hillard CJ, Lane RH, Majnik A) Physiol Rep 2020 Apr;8(8):e14407 PMID: 32333646 PMCID: PMC7183239 SCOPUS ID: 2-s2.0-85084031438 04/26/2020       13 Citations
  • Sex, stress, and prefrontal cortex: influence of biological sex on stress-promoted cocaine seeking. (Doncheck EM, Liddiard GT, Konrath CD, Liu X, Yu L, Urbanik LA, Herbst MR, DeBaker MC, Raddatz N, Van Newenhizen EC, Mathy J, Gilmartin MR, Liu QS, Hillard CJ, Mantsch JR) Neuropsychopharmacology 2020 Nov;45(12):1974-1985 PMID: 32303052 PMCID: PMC7547655 SCOPUS ID: 2-s2.0-85084141235 04/18/2020       28 Citations
  • Circadian Misalignment of the 24-hour Profile of Endocannabinoid 2-Arachidonoylglycerol (2-AG) in Obese Adults. (Hanlon EC, Leproult R, Stuhr KL, Doncheck EM, Hillard CJ, Van Cauter E) J Clin Endocrinol Metab 2020 Mar 01;105(3):792-802 PMID: 31970413 PMCID: PMC7015463 SCOPUS ID: 2-s2.0-85079347809 01/24/2020       6 Citations
  • Stress-induced modulation of endocannabinoid signaling leads to delayed strengthening of synaptic connectivity in the amygdala. (Yasmin F, Colangeli R, Morena M, Filipski S, van der Stelt M, Pittman QJ, Hillard CJ, Teskey GC, McEwen BS, Hill MN, Chattarji S) Proc Natl Acad Sci U S A 2020 Jan 07;117(1):650-655 PMID: 31843894 PMCID: PMC6955336 SCOPUS ID: 2-s2.0-85077654645 12/18/2019       43 Citations
  • Psychological and endocannabinoid responses to aerobic exercise in substance use disorder patients. (Brellenthin AG, Crombie KM, Hillard CJ, Brown RT, Koltyn KF) Subst Abus 2021;42(3):272-283 PMID: 31729933 PMCID: PMC7225058 SCOPUS ID: 2-s2.0-85075356343 11/16/2019       17 Citations
  • Patterns of Cannabis Use in Patients With Cyclic Vomiting Syndrome. (Venkatesan T, Hillard CJ, Rein L, Banerjee A, Lisdahl K) Clin Gastroenterol Hepatol 2020 May;18(5):1082-1090.e2 PMID: 31352091 SCOPUS ID: 2-s2.0-85081912688 07/29/2019       23 Citations
  • Loss of exercise- and stress-induced increases in circulating 2-arachidonoylglycerol concentrations in adults with chronic PTSD. (Crombie KM, Leitzelar BN, Brellenthin AG, Hillard CJ, Koltyn KF) Biol Psychol 2019 Jul;145:1-7 PMID: 30978371 SCOPUS ID: 2-s2.0-85064154072 04/13/2019       33 Citations
  • Serum Endocannabinoid and Mood Changes after Exercise in Major Depressive Disorder. (Meyer JD, Crombie KM, Cook DB, Hillard CJ, Koltyn KF) Med Sci Sports Exerc 2019 Sep;51(9):1909-1917 PMID: 30973483 PMCID: PMC6727944 SCOPUS ID: 2-s2.0-85070841260 04/12/2019       60 Citations
  • Cannabinoid CB2R receptors are upregulated with corneal injury and regulate the course of corneal wound healing. (Murataeva N, Miller S, Dhopeshwarkar A, Leishman E, Daily L, Taylor X, Morton B, Lashmet M, Bradshaw H, Hillard CJ, Romero J, Straiker A) Exp Eye Res 2019 May;182:74-84 PMID: 30905716 PMCID: PMC6504573 SCOPUS ID: 2-s2.0-85063275776 03/25/2019       24 Citations
  • Early life stress alters the developmental trajectory of corticolimbic endocannabinoid signaling in male rats. (Hill MN, Eiland L, Lee TTY, Hillard CJ, McEwen BS) Neuropharmacology 2019 Mar 01;146:154-162 PMID: 30496752 PMCID: PMC6347425 SCOPUS ID: 2-s2.0-85057629348 11/30/2018       36 Citations
  • Recent trends in cyclic vomiting syndrome-associated hospitalisations with liberalisation of cannabis use in the state of Colorado. (Bhandari S, Jha P, Lisdahl KM, Hillard CJ, Venkatesan T) Intern Med J 2019 May;49(5):649-655 PMID: 30426628 SCOPUS ID: 2-s2.0-85065707659 11/15/2018       27 Citations
  • Revisiting cannabinoid receptor 2 expression and function in murine retina. (Borowska-Fielding J, Murataeva N, Smith B, Szczesniak AM, Leishman E, Daily L, Toguri JT, Hillard CJ, Romero J, Bradshaw H, Kelly MEM, Straiker A) Neuropharmacology 2018 Oct;141:21-31 PMID: 30121200 PMCID: PMC6314309 SCOPUS ID: 2-s2.0-85053042908 08/20/2018       14 Citations
  • Role of endocannabinoids in the hippocampus and amygdala in emotional memory and plasticity. (Segev A, Korem N, Mizrachi Zer-Aviv T, Abush H, Lange R, Sauber G, Hillard CJ, Akirav I) Neuropsychopharmacology 2018 Sep;43(10):2017-2027 PMID: 29977073 PMCID: PMC6098035 SCOPUS ID: 2-s2.0-85049559833 07/07/2018       55 Citations
  • Role for fatty acid amide hydrolase (FAAH) in the leptin-mediated effects on feeding and energy balance. (Balsevich G, Sticht M, Bowles NP, Singh A, Lee TTY, Li Z, Chelikani PK, Lee FS, Borgland SL, Hillard CJ, McEwen BS, Hill MN) Proc Natl Acad Sci U S A 2018 Jul 17;115(29):7605-7610 PMID: 29967158 PMCID: PMC6055171 SCOPUS ID: 2-s2.0-85049982499 07/04/2018       28 Citations
  • The Lateral Habenula Directs Coping Styles Under Conditions of Stress via Recruitment of the Endocannabinoid System. (Berger AL, Henricks AM, Lugo JM, Wright HR, Warrick CR, Sticht MA, Morena M, Bonilla I, Laredo SA, Craft RM, Parsons LH, Grandes PR, Hillard CJ, Hill MN, McLaughlin RJ) Biol Psychiatry 2018 Oct 15;84(8):611-623 PMID: 29887035 PMCID: PMC6162143 SCOPUS ID: 2-s2.0-85048097931 06/12/2018       35 Citations
  • Cannabinoid CB2 receptors in the mouse brain: relevance for Alzheimer's disease. (López A, Aparicio N, Pazos MR, Grande MT, Barreda-Manso MA, Benito-Cuesta I, Vázquez C, Amores M, Ruiz-Pérez G, García-García E, Beatka M, Tolón RM, Dittel BN, Hillard CJ, Romero J) J Neuroinflammation 2018 May 24;15(1):158 PMID: 29793509 PMCID: PMC5968596 SCOPUS ID: 2-s2.0-85047540052 05/26/2018       91 Citations
  • Chronic treatment with URB597 ameliorates post-stress symptoms in a rat model of PTSD. (Fidelman S, Mizrachi Zer-Aviv T, Lange R, Hillard CJ, Akirav I) Eur Neuropsychopharmacol 2018 May;28(5):630-642 PMID: 29519609 SCOPUS ID: 2-s2.0-85042367663 03/10/2018       48 Citations
  • Psychobiological Responses to Aerobic Exercise in Individuals With Posttraumatic Stress Disorder. (Crombie KM, Brellenthin AG, Hillard CJ, Koltyn KF) J Trauma Stress 2018 Feb;31(1):134-145 PMID: 29388710 SCOPUS ID: 2-s2.0-85043318022 02/02/2018       40 Citations
  • Stress Promotes Drug Seeking Through Glucocorticoid-Dependent Endocannabinoid Mobilization in the Prelimbic Cortex. (McReynolds JR, Doncheck EM, Li Y, Vranjkovic O, Graf EN, Ogasawara D, Cravatt BF, Baker DA, Liu QS, Hillard CJ, Mantsch JR) Biol Psychiatry 2018 Jul 15;84(2):85-94 PMID: 29100630 PMCID: PMC5889367 SCOPUS ID: 2-s2.0-85033680278 11/05/2017       41 Citations
  • Increase in the circulating endocannabinoid 2-arachidonoylglycerol is associated with gabapentin use in septic ICU patients. (Raff H, Kramer DJ, Hillard CJ) Endocrine 2017 Oct;58(1):203-204 PMID: 28875451 SCOPUS ID: 2-s2.0-85028974393 09/07/2017    
  • 17β-Estradiol Potentiates the Reinstatement of Cocaine Seeking in Female Rats: Role of the Prelimbic Prefrontal Cortex and Cannabinoid Type-1 Receptors. (Doncheck EM, Urbanik LA, DeBaker MC, Barron LM, Liddiard GT, Tuscher JJ, Frick KM, Hillard CJ, Mantsch JR) Neuropsychopharmacology 2018 Mar;43(4):781-790 PMID: 28825421 PMCID: PMC5809785 SCOPUS ID: 2-s2.0-85041731033 08/22/2017       31 Citations
  • Endocannabinoid Transport Proteins: Discovery of Tools to Study Sterol Carrier Protein-2. (Hillard CJ, Huang H, Vogt CD, Rodrigues BE, Neumann TS, Sem DS, Schroeder F, Cunningham CW) Methods Enzymol 2017;593:99-121 PMID: 28750817 PMCID: PMC6904209 SCOPUS ID: 2-s2.0-85024124936 07/29/2017       24 Citations
  • Cannabinoid Receptor 1 and Fatty Acid Amide Hydrolase Contribute to Operant Sensation Seeking in Mice. (Helfand AI, Olsen CM, Hillard CJ) Int J Mol Sci 2017 Jul 27;18(8) PMID: 28749428 PMCID: PMC5578025 SCOPUS ID: 2-s2.0-85026663350 07/28/2017       3 Citations
  • Host interleukin 6 production regulates inflammation but not tryptophan metabolism in the brain during murine GVHD. (Belle L, Zhou V, Stuhr KL, Beatka M, Siebers EM, Knight JM, Lawlor MW, Weaver C, Hashizume M, Hillard CJ, Drobyski WR) JCI Insight 2017 Jul 20;2(14) PMID: 28724796 PMCID: PMC5518565 SCOPUS ID: 2-s2.0-85033974707 07/21/2017       12 Citations
  • Circulating Endocannabinoids: From Whence Do They Come and Where are They Going? (Hillard CJ) Neuropsychopharmacology 2018 Jan;43(1):155-172 PMID: 28653665 PMCID: PMC5719092 SCOPUS ID: 2-s2.0-85036605314 06/28/2017       267 Citations
  • Role of beta-catenin and endocannabinoids in the nucleus accumbens in extinction in rats exposed to shock and reminders. (Korem N, Lange R, Hillard CJ, Akirav I) Neuroscience 2017 Aug 15;357:285-294 PMID: 28624572 SCOPUS ID: 2-s2.0-85021388226 06/19/2017       20 Citations
  • Altered striatal endocannabinoid signaling in a transgenic mouse model of spinocerebellar ataxia type-3. (Rodríguez-Cueto C, Hernández-Gálvez M, Hillard CJ, Maciel P, Valdeolivas S, Ramos JA, Gómez-Ruiz M, Fernández-Ruiz J) PLoS One 2017;12(4):e0176521 PMID: 28448548 PMCID: PMC5407801 SCOPUS ID: 2-s2.0-85018275217 04/28/2017       5 Citations
  • Endocannabinoid and Opioid System Interactions in Exercise-Induced Hypoalgesia. (Crombie KM, Brellenthin AG, Hillard CJ, Koltyn KF) Pain Med 2018 Jan 01;19(1):118-123 PMID: 28387833 PMCID: PMC6454785 SCOPUS ID: 2-s2.0-85041366186 04/08/2017       63 Citations
  • Endocannabinoid and Mood Responses to Exercise in Adults with Varying Activity Levels. (Brellenthin AG, Crombie KM, Hillard CJ, Koltyn KF) Med Sci Sports Exerc 2017 Aug;49(8):1688-1696 PMID: 28319590 SCOPUS ID: 2-s2.0-85015696439 03/21/2017       75 Citations
  • Upregulation of fatty acid amide hydrolase in the dorsal periaqueductal gray is associated with neuropathic pain and reduced heart rate in rats. (Dean C, Hillard CJ, Seagard JL, Hopp FA, Hogan QH) Am J Physiol Regul Integr Comp Physiol 2017 Apr 01;312(4):R585-R596 PMID: 28148494 PMCID: PMC6668034 SCOPUS ID: 2-s2.0-85017328671 02/06/2017       5 Citations
  • Endocannabinoid Signaling and the Hypothalamic-Pituitary-Adrenal Axis. (Hillard CJ, Beatka M, Sarvaideo J) Compr Physiol 2016 Dec 06;7(1):1-15 PMID: 28134998 PMCID: PMC5871916 SCOPUS ID: 2-s2.0-85020983619 01/31/2017       68 Citations
  • Dysregulation of the endocannabinoid signaling system in the cerebellum and brainstem in a transgenic mouse model of spinocerebellar ataxia type-3. (Rodríguez-Cueto C, Hernández-Gálvez M, Hillard CJ, Maciel P, García-García L, Valdeolivas S, Pozo MA, Ramos JA, Gómez-Ruiz M, Fernández-Ruiz J) Neuroscience 2016 Dec 17;339:191-209 PMID: 27717809 SCOPUS ID: 2-s2.0-84992735493 11/05/2016       20 Citations
  • FAAH Gene Variation Moderates Stress Response and Symptom Severity in Patients with Posttraumatic Stress Disorder and Comorbid Alcohol Dependence. (Spagnolo PA, Ramchandani VA, Schwandt ML, Kwako LE, George DT, Mayo LM, Hillard CJ, Heilig M) Alcohol Clin Exp Res 2016 Nov;40(11):2426-2434 PMID: 27716956 PMCID: PMC5748341 SCOPUS ID: 2-s2.0-84988859573 10/21/2016       62 Citations
  • Seeing through the smoke: Human and animal studies of cannabis use and endocannabinoid signalling in corticolimbic networks. (Silveira MM, Arnold JC, Laviolette SR, Hillard CJ, Celorrio M, Aymerich MS, Adams WK) Neurosci Biobehav Rev 2017 May;76(Pt B):380-395 PMID: 27639448 PMCID: PMC5350061 SCOPUS ID: 2-s2.0-84998893278 09/19/2016       27 Citations
  • Marijuana users do not have increased healthcare utilization: A National Health and Nutrition Examination Survey (NHANES) study. (Bhandari S, Hillard CJ, Venkatesan T) Eur J Intern Med 2016 Oct;34:e9-e10 PMID: 27499177 SCOPUS ID: 2-s2.0-84994172697 08/09/2016       5 Citations
  • Fatty acid amide hydrolase inhibition for the symptomatic relief of Parkinson's disease. (Celorrio M, Fernández-Suárez D, Rojo-Bustamante E, Echeverry-Alzate V, Ramírez MJ, Hillard CJ, López-Moreno JA, Maldonado R, Oyarzábal J, Franco R, Aymerich MS) Brain Behav Immun 2016 Oct;57:94-105 PMID: 27318096 SCOPUS ID: 2-s2.0-84977659397 06/19/2016       51 Citations
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  • Endocannabinoid-related lipids are increased during an episode of cyclic vomiting syndrome. (Venkatesan T, Zadvornova Y, Raff H, Hillard CJ) Neurogastroenterol Motil 2016 Sep;28(9):1409-18 PMID: 27098832 PMCID: PMC5002231 SCOPUS ID: 2-s2.0-84983490957 04/22/2016       36 Citations
  • Sustained glucocorticoid exposure recruits cortico-limbic CRH signaling to modulate endocannabinoid function. (Gray JM, Wilson CD, Lee TT, Pittman QJ, Deussing JM, Hillard CJ, McEwen BS, Schulkin J, Karatsoreos IN, Patel S, Hill MN) Psychoneuroendocrinology 2016 Apr;66:151-8 PMID: 26821211 PMCID: PMC4788523 SCOPUS ID: 2-s2.0-84960901292 01/29/2016       44 Citations
  • The Endocannabinoid Signaling System in the CNS: A Primer. (Hillard CJ) Int Rev Neurobiol 2015;125:1-47 PMID: 26638763 PMCID: PMC6813823 SCOPUS ID: 2-s2.0-84949035273 12/08/2015       85 Citations
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  • The endocannabinoid system in guarding against fear, anxiety and stress. (Lutz B, Marsicano G, Maldonado R, Hillard CJ) Nat Rev Neurosci 2015 Dec;16(12):705-18 PMID: 26585799 PMCID: PMC5871913 SCOPUS ID: 2-s2.0-84947923864 11/21/2015       329 Citations
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  • Disruption of peri-adolescent endocannabinoid signaling modulates adult neuroendocrine and behavioral responses to stress in male rats. (Lee TT, Hill MN, Hillard CJ, Gorzalka BB) Neuropharmacology 2015 Dec;99:89-97 PMID: 26192544 SCOPUS ID: 2-s2.0-84938261822 07/21/2015       19 Citations
  • Circulating endocannabinoids during hematopoietic stem cell transplantation: A pilot study. (Knight JM, Szabo A, Zhao S, Lyness JM, Sahler OJ, Liesveld JL, Sander T, Rizzo JD, Hillard CJ, Moynihan JA) Neurobiol Stress 2015;2:44-50 PMID: 26114153 PMCID: PMC4476410 SCOPUS ID: 2-s2.0-84934762315 06/27/2015       10 Citations
  • An endocannabinoid system is present in the mouse olfactory epithelium but does not modulate olfaction. (Hutch CR, Hillard CJ, Jia C, Hegg CC) Neuroscience 2015 Aug 06;300:539-53 PMID: 26037800 PMCID: PMC4485596 SCOPUS ID: 2-s2.0-84930959429 06/04/2015       14 Citations
  • Endocannabinoids regulate the activity of astrocytic hemichannels and the microglial response against an injury: In vivo studies. (Vázquez C, Tolón RM, Pazos MR, Moreno M, Koester EC, Cravatt BF, Hillard CJ, Romero J) Neurobiol Dis 2015 Jul;79:41-50 PMID: 25917763 SCOPUS ID: 2-s2.0-84928599358 04/29/2015       35 Citations
  • A peripheral endocannabinoid mechanism contributes to glucocorticoid-mediated metabolic syndrome. (Bowles NP, Karatsoreos IN, Li X, Vemuri VK, Wood JA, Li Z, Tamashiro KL, Schwartz GJ, Makriyannis AM, Kunos G, Hillard CJ, McEwen BS, Hill MN) Proc Natl Acad Sci U S A 2015 Jan 06;112(1):285-90 PMID: 25535367 PMCID: PMC4291642 SCOPUS ID: 2-s2.0-84920450557 12/24/2014       82 Citations
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  • Circadian rhythm of circulating levels of the endocannabinoid 2-arachidonoylglycerol. (Hanlon EC, Tasali E, Leproult R, Stuhr KL, Doncheck E, de Wit H, Hillard CJ, Van Cauter E) J Clin Endocrinol Metab 2015 Jan;100(1):220-6 PMID: 25368979 PMCID: PMC5399498 SCOPUS ID: 2-s2.0-84920614665 11/05/2014       68 Citations
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  • Monoacylglycerol lipase inhibitor JZL184 is neuroprotective and alters glial cell phenotype in the chronic MPTP mouse model. (Fernández-Suárez D, Celorrio M, Riezu-Boj JI, Ugarte A, Pacheco R, González H, Oyarzabal J, Hillard CJ, Franco R, Aymerich MS) Neurobiol Aging 2014 Nov;35(11):2603-2616 PMID: 24973119 SCOPUS ID: 2-s2.0-84922880383 06/29/2014       72 Citations
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  • Differential muscle hypertrophy is associated with satellite cell numbers and Akt pathway activation following activin type IIB receptor inhibition in Mtm1 p.R69C mice. (Lawlor MW, Viola MG, Meng H, Edelstein RV, Liu F, Yan K, Luna EJ, Lerch-Gaggl A, Hoffmann RG, Pierson CR, Buj-Bello A, Lachey JL, Pearsall S, Yang L, Hillard CJ, Beggs AH) Am J Pathol 2014 Jun;184(6):1831-42 PMID: 24726641 PMCID: PMC4044712 SCOPUS ID: 2-s2.0-84901020192 04/15/2014       27 Citations
  • Sterol carrier protein-2: binding protein for endocannabinoids. (Liedhegner ES, Vogt CD, Sem DS, Cunningham CW, Hillard CJ) Mol Neurobiol 2014 Aug;50(1):149-58 PMID: 24510313 PMCID: PMC4450258 SCOPUS ID: 2-s2.0-84911004168 02/11/2014       31 Citations
  • Endocannabinoid signaling in hypothalamic-pituitary-adrenocortical axis recovery following stress: effects of indirect agonists and comparison of male and female mice. (Roberts CJ, Stuhr KL, Hutz MJ, Raff H, Hillard CJ) Pharmacol Biochem Behav 2014 Feb;117:17-24 PMID: 24316201 PMCID: PMC3929302 SCOPUS ID: 2-s2.0-84890264813 12/10/2013       42 Citations
  • Endocannabinoid signaling in the etiology and treatment of major depressive illness. (Hillard CJ, Liu QS) Curr Pharm Des 2014;20(23):3795-811 PMID: 24180398 PMCID: PMC4002665 SCOPUS ID: 2-s2.0-84916885839 11/05/2013       52 Citations
  • Endocannabinoids, monoamines and stress (Hillard CJ) Endocannabinoid Regulation of Monoamines in Psychiatric and Neurological Disorders 1 November 2013:173-212 SCOPUS ID: 2-s2.0-84929577473 11/01/2013    
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  • Reductions in circulating endocannabinoid levels in individuals with post-traumatic stress disorder following exposure to the World Trade Center attacks. (Hill MN, Bierer LM, Makotkine I, Golier JA, Galea S, McEwen BS, Hillard CJ, Yehuda R) Psychoneuroendocrinology 2013 Dec;38(12):2952-61 PMID: 24035186 PMCID: PMC3870889 SCOPUS ID: 2-s2.0-84888299927 09/17/2013       184 Citations
  • Mechanisms of cannabidiol neuroprotection in hypoxic-ischemic newborn pigs: role of 5HT(1A) and CB2 receptors. (Pazos MR, Mohammed N, Lafuente H, Santos M, Martínez-Pinilla E, Moreno E, Valdizan E, Romero J, Pazos A, Franco R, Hillard CJ, Alvarez FJ, Martínez-Orgado J) Neuropharmacology 2013 Aug;71:282-91 PMID: 23587650 SCOPUS ID: 2-s2.0-84878128163 04/17/2013       178 Citations
  • Upregulation of CB₁ receptor binding in the ventromedial prefrontal cortex promotes proactive stress-coping strategies following chronic stress exposure. (McLaughlin RJ, Hill MN, Dang SS, Wainwright SR, Galea LA, Hillard CJ, Gorzalka BB) Behav Brain Res 2013 Jan 15;237:333-7 PMID: 23047058 PMCID: PMC3501995 SCOPUS ID: 2-s2.0-84867615880 10/11/2012       50 Citations
  • Temporal changes in N-acylethanolamine content and metabolism throughout the peri-adolescent period. (Lee TT, Hill MN, Hillard CJ, Gorzalka BB) Synapse 2013 Jan;67(1):4-10 PMID: 22987804 PMCID: PMC3510355 SCOPUS ID: 2-s2.0-84870319187 09/19/2012       58 Citations
  • Disruption of fatty acid amide hydrolase activity prevents the effects of chronic stress on anxiety and amygdalar microstructure. (Hill MN, Kumar SA, Filipski SB, Iverson M, Stuhr KL, Keith JM, Cravatt BF, Hillard CJ, Chattarji S, McEwen BS) Mol Psychiatry 2013 Oct;18(10):1125-35 PMID: 22776900 PMCID: PMC4148304 SCOPUS ID: 2-s2.0-84884674660 07/11/2012       172 Citations
  • Acute stress increases circulating anandamide and other N-acylethanolamines in healthy humans. (Dlugos A, Childs E, Stuhr KL, Hillard CJ, de Wit H) Neuropsychopharmacology 2012 Oct;37(11):2416-27 PMID: 22763622 PMCID: PMC3442338 SCOPUS ID: 2-s2.0-84866378334 07/06/2012       159 Citations
  • Circulating endocannabinoid concentrations and sexual arousal in women. (Klein C, Hill MN, Chang SC, Hillard CJ, Gorzalka BB) J Sex Med 2012 Jun;9(6):1588-601 PMID: 22462722 PMCID: PMC3856894 SCOPUS ID: 2-s2.0-84861801063 04/03/2012       25 Citations
  • Serum contents of endocannabinoids are correlated with blood pressure in depressed women. (Ho WS, Hill MN, Miller GE, Gorzalka BB, Hillard CJ) Lipids Health Dis 2012 Feb 28;11:32 PMID: 22373123 PMCID: PMC3334711 SCOPUS ID: 2-s2.0-84857410633 03/01/2012       33 Citations
  • Prefrontal cortical anandamide signaling coordinates coping responses to stress through a serotonergic pathway. (McLaughlin RJ, Hill MN, Bambico FR, Stuhr KL, Gobbi G, Hillard CJ, Gorzalka BB) Eur Neuropsychopharmacol 2012 Sep;22(9):664-71 PMID: 22325231 PMCID: PMC3366159 SCOPUS ID: 2-s2.0-84865033949 02/14/2012       87 Citations
  • Swim stress differentially affects limbic contents of 2-arachidonoylglycerol and 2-oleoylglycerol. (Roberts CJ, Stuhr KL, Hillard CJ) Neuroscience 2012 Mar 01;204:74-82 PMID: 22192839 PMCID: PMC3288304 SCOPUS ID: 2-s2.0-84857125720 12/24/2011       15 Citations
  • Contributions of endocannabinoid signaling to psychiatric disorders in humans: genetic and biochemical evidence. (Hillard CJ, Weinlander KM, Stuhr KL) Neuroscience 2012 Mar 01;204:207-29 PMID: 22123166 PMCID: PMC3288440 SCOPUS ID: 2-s2.0-84857125719 11/30/2011       142 Citations
  • Chronic, noninvasive glucocorticoid administration suppresses limbic endocannabinoid signaling in mice. (Bowles NP, Hill MN, Bhagat SM, Karatsoreos IN, Hillard CJ, McEwen BS) Neuroscience 2012 Mar 01;204:83-9 PMID: 21939741 PMCID: PMC3697830 SCOPUS ID: 2-s2.0-84857128136 09/24/2011       49 Citations
  • Acute restraint stress enhances hippocampal endocannabinoid function via glucocorticoid receptor activation. (Wang M, Hill MN, Zhang L, Gorzalka BB, Hillard CJ, Alger BE) J Psychopharmacol 2012 Jan;26(1):56-70 PMID: 21890595 PMCID: PMC3373303 SCOPUS ID: 2-s2.0-84863011182 09/06/2011       112 Citations
  • Cannabinoid receptor involvement in stress-induced cocaine reinstatement: potential interaction with noradrenergic pathways. (Vaughn LK, Mantsch JR, Vranjkovic O, Stroh G, Lacourt M, Kreutter M, Hillard CJ) Neuroscience 2012 Mar 01;204:117-24 PMID: 21871539 PMCID: PMC3422566 SCOPUS ID: 2-s2.0-84857125721 08/30/2011       36 Citations
  • Recruitment of prefrontal cortical endocannabinoid signaling by glucocorticoids contributes to termination of the stress response. (Hill MN, McLaughlin RJ, Pan B, Fitzgerald ML, Roberts CJ, Lee TT, Karatsoreos IN, Mackie K, Viau V, Pickel VM, McEwen BS, Liu QS, Gorzalka BB, Hillard CJ) J Neurosci 2011 Jul 20;31(29):10506-15 PMID: 21775596 PMCID: PMC3179266 SCOPUS ID: 2-s2.0-79960676744 07/22/2011       286 Citations
  • Alterations in corticolimbic dendritic morphology and emotional behavior in cannabinoid CB1 receptor-deficient mice parallel the effects of chronic stress. (Hill MN, Hillard CJ, McEwen BS) Cereb Cortex 2011 Sep;21(9):2056-64 PMID: 21263035 PMCID: PMC3155602 SCOPUS ID: 2-s2.0-79959969118 01/26/2011       97 Citations
  • Natural and synthetic corticosteroids inhibit uptake 2-mediated transport in CNS neurons. (Hill JE, Makky K, Shrestha L, Hillard CJ, Gasser PJ) Physiol Behav 2011 Aug 03;104(2):306-11 PMID: 21081135 SCOPUS ID: 2-s2.0-79958850049 11/18/2010       23 Citations
  • Sex difference in cell proliferation in developing rat amygdala mediated by endocannabinoids has implications for social behavior. (Krebs-Kraft DL, Hill MN, Hillard CJ, McCarthy MM) Proc Natl Acad Sci U S A 2010 Nov 23;107(47):20535-40 PMID: 21059913 PMCID: PMC2996668 SCOPUS ID: 2-s2.0-78650553198 11/10/2010       95 Citations
  • Neuroprotection by a mitochondria-targeted drug in a Parkinson's disease model. (Ghosh A, Chandran K, Kalivendi SV, Joseph J, Antholine WE, Hillard CJ, Kanthasamy A, Kanthasamy A, Kalyanaraman B) Free Radic Biol Med 2010 Dec 01;49(11):1674-84 PMID: 20828611 PMCID: PMC4020411 SCOPUS ID: 2-s2.0-78049357951 09/11/2010       154 Citations
  • Inhibition of fatty acid amide hydrolase suppresses referred hyperalgesia induced by bladder inflammation. (Merriam FV, Wang ZY, Hillard CJ, Stuhr KL, Bjorling DE) BJU Int 2011 Oct;108(7):1145-9 PMID: 20804480 PMCID: PMC3505723 SCOPUS ID: 2-s2.0-80052797640 09/02/2010       36 Citations
  • Fast feedback inhibition of the HPA axis by glucocorticoids is mediated by endocannabinoid signaling. (Evanson NK, Tasker JG, Hill MN, Hillard CJ, Herman JP) Endocrinology 2010 Oct;151(10):4811-9 PMID: 20702575 PMCID: PMC2946139 SCOPUS ID: 2-s2.0-77957276332 08/13/2010       246 Citations
  • Deficiency in endocannabinoid signaling in the nucleus accumbens induced by chronic unpredictable stress. (Wang W, Sun D, Pan B, Roberts CJ, Sun X, Hillard CJ, Liu QS) Neuropsychopharmacology 2010 Oct;35(11):2249-61 PMID: 20664582 PMCID: PMC3055309 SCOPUS ID: 2-s2.0-78651314453 07/29/2010       92 Citations
  • Endocannabinoid modulation of hyperaemia evoked by physiologically relevant stimuli in the rat primary somatosensory cortex. (Ho WS, Patel S, Thompson JR, Roberts CJ, Stuhr KL, Hillard CJ) Br J Pharmacol 2010 Jun;160(3):736-46 PMID: 20590576 PMCID: PMC2931572 SCOPUS ID: 2-s2.0-77952633980 07/02/2010       10 Citations
  • Endocannabinoid signalling: has it got rhythm? (Vaughn LK, Denning G, Stuhr KL, de Wit H, Hill MN, Hillard CJ) Br J Pharmacol 2010 Jun;160(3):530-43 PMID: 20590563 PMCID: PMC2931554 SCOPUS ID: 2-s2.0-77952622170 07/02/2010       132 Citations
  • Retrograde release of endocannabinoids inhibits presynaptic GABA release to second-order baroreceptive neurons in NTS. (Chen CY, Bonham AC, Dean C, Hopp FA, Hillard CJ, Seagard JL) Auton Neurosci 2010 Dec 08;158(1-2):44-50 PMID: 20580326 PMCID: PMC2976795 SCOPUS ID: 2-s2.0-78149408566 06/29/2010       18 Citations
  • Endogenous cannabinoid signaling is essential for stress adaptation. (Hill MN, McLaughlin RJ, Bingham B, Shrestha L, Lee TT, Gray JM, Hillard CJ, Gorzalka BB, Viau V) Proc Natl Acad Sci U S A 2010 May 18;107(20):9406-11 PMID: 20439721 PMCID: PMC2889099 SCOPUS ID: 2-s2.0-77952717194 05/05/2010       278 Citations
  • Rapid elevations in limbic endocannabinoid content by glucocorticoid hormones in vivo. (Hill MN, Karatsoreos IN, Hillard CJ, McEwen BS) Psychoneuroendocrinology 2010 Oct;35(9):1333-8 PMID: 20399021 PMCID: PMC2914801 SCOPUS ID: 2-s2.0-77956618349 04/20/2010       138 Citations
  • Estrogenic regulation of limbic cannabinoid receptor binding. (Riebe CJ, Hill MN, Lee TT, Hillard CJ, Gorzalka BB) Psychoneuroendocrinology 2010 Sep;35(8):1265-9 PMID: 20207489 PMCID: PMC2933663 SCOPUS ID: 2-s2.0-77955578727 03/09/2010       105 Citations
  • Obesity-related dyslipidemia associated with FAAH, independent of insulin response, in multigenerational families of Northern European descent. (Zhang Y, Sonnenberg GE, Baye TM, Littrell J, Gunnell J, DeLaForest A, MacKinney E, Hillard CJ, Kissebah AH, Olivier M, Wilke RA) Pharmacogenomics 2009 Dec;10(12):1929-39 PMID: 19958092 PMCID: PMC3003434 SCOPUS ID: 2-s2.0-73649131984 12/05/2009       26 Citations
  • Oxidants induce alternative splicing of alpha-synuclein: Implications for Parkinson's disease. (Kalivendi SV, Yedlapudi D, Hillard CJ, Kalyanaraman B) Free Radic Biol Med 2010 Feb 01;48(3):377-83 PMID: 19857570 PMCID: PMC4485429 SCOPUS ID: 2-s2.0-73449099224 10/28/2009       39 Citations
  • The therapeutic potential of the endocannabinoid system for the development of a novel class of antidepressants. (Hill MN, Hillard CJ, Bambico FR, Patel S, Gorzalka BB, Gobbi G) Trends Pharmacol Sci 2009 Sep;30(9):484-93 PMID: 19732971 SCOPUS ID: 2-s2.0-69549116206 09/08/2009       140 Citations
  • Suppression of amygdalar endocannabinoid signaling by stress contributes to activation of the hypothalamic-pituitary-adrenal axis. (Hill MN, McLaughlin RJ, Morrish AC, Viau V, Floresco SB, Hillard CJ, Gorzalka BB) Neuropsychopharmacology 2009 Dec;34(13):2733-45 PMID: 19710634 PMCID: PMC3197779 SCOPUS ID: 2-s2.0-70449529389 08/28/2009       244 Citations
  • Blockade of 2-arachidonoylglycerol hydrolysis by selective monoacylglycerol lipase inhibitor 4-nitrophenyl 4-(dibenzo[d][1,3]dioxol-5-yl(hydroxy)methyl)piperidine-1-carboxylate (JZL184) Enhances retrograde endocannabinoid signaling. (Pan B, Wang W, Long JZ, Sun D, Hillard CJ, Cravatt BF, Liu QS) J Pharmacol Exp Ther 2009 Nov;331(2):591-7 PMID: 19666749 PMCID: PMC2775254 SCOPUS ID: 2-s2.0-70350455918 08/12/2009       136 Citations
  • Endogenous cannabinoid signaling is required for voluntary exercise-induced enhancement of progenitor cell proliferation in the hippocampus. (Hill MN, Titterness AK, Morrish AC, Carrier EJ, Lee TT, Gil-Mohapel J, Gorzalka BB, Hillard CJ, Christie BR) Hippocampus 2010 Apr;20(4):513-23 PMID: 19489006 PMCID: PMC2847038 SCOPUS ID: 2-s2.0-77950113882 06/03/2009       108 Citations
  • Differential endocannabinoid regulation of baroreflex-evoked sympathoinhibition in normotensive versus hypertensive rats. (Brozoski DT, Dean C, Hopp FA, Hillard CJ, Seagard JL) Auton Neurosci 2009 Oct 05;150(1-2):82-93 PMID: 19464961 PMCID: PMC3815570 SCOPUS ID: 2-s2.0-69349092082 05/26/2009       26 Citations
  • Circulating endocannabinoids and N-acyl ethanolamines are differentially regulated in major depression and following exposure to social stress. (Hill MN, Miller GE, Carrier EJ, Gorzalka BB, Hillard CJ) Psychoneuroendocrinology 2009 Sep;34(8):1257-62 PMID: 19394765 PMCID: PMC2716432 SCOPUS ID: 2-s2.0-67650617724 04/28/2009       245 Citations
  • Differential effects of the antidepressants tranylcypromine and fluoxetine on limbic cannabinoid receptor binding and endocannabinoid contents (Journal of Neural Transmission (2008) 115, (1673-1679) DOI: 10.1007/s00702-008-0131-7) (Hill MN, Ho WSV, Hillard CJ, Gorzalka BB) Journal of Neural Transmission February 2009;116(2):141 SCOPUS ID: 2-s2.0-59849096250 02/01/2009    
  • Role of endocannabinoid signaling in anxiety and depression. (Patel S, Hillard CJ) Curr Top Behav Neurosci 2009;1:347-71 PMID: 21104391 PMCID: PMC3808114 SCOPUS ID: 2-s2.0-79952118933 01/01/2009       46 Citations
  • D2 dopamine receptor activation facilitates endocannabinoid-mediated long-term synaptic depression of GABAergic synaptic transmission in midbrain dopamine neurons via cAMP-protein kinase A signaling. (Pan B, Hillard CJ, Liu QS) J Neurosci 2008 Dec 24;28(52):14018-30 PMID: 19109485 PMCID: PMC2656602 SCOPUS ID: 2-s2.0-58149373942 12/26/2008       110 Citations
  • Differential effects of the antidepressants tranylcypromine and fluoxetine on limbic cannabinoid receptor binding and endocannabinoid contents. (Hill MN et al.) J Neural Transm 2009 Feb;116(2):141 PMID: 19093190 12/19/2008    
  • Genetic variation in cannabinoid receptor 1 (CNR1) is associated with derangements in lipid homeostasis, independent of body mass index. (Baye TM, Zhang Y, Smith E, Hillard CJ, Gunnell J, Myklebust J, James R, Kissebah AH, Olivier M, Wilke RA) Pharmacogenomics 2008 Nov;9(11):1647-56 PMID: 19018721 PMCID: PMC2784739 SCOPUS ID: 2-s2.0-61549101858 11/21/2008       45 Citations
  • Differential effects of the antidepressants tranylcypromine and fluoxetine on limbic cannabinoid receptor binding and endocannabinoid contents. (Hill MN, Ho WS, Hillard CJ, Gorzalka BB) J Neural Transm (Vienna) 2008 Dec;115(12):1673-9 PMID: 18974922 PMCID: PMC2992975 SCOPUS ID: 2-s2.0-57049099128 11/01/2008       65 Citations
  • Role of cannabinoids and endocannabinoids in cerebral ischemia. (Hillard CJ) Curr Pharm Des 2008;14(23):2347-61 PMID: 18781985 PMCID: PMC2581413 SCOPUS ID: 2-s2.0-52949119940 09/11/2008       105 Citations
  • Regional alterations in the endocannabinoid system in an animal model of depression: effects of concurrent antidepressant treatment. (Hill MN, Carrier EJ, McLaughlin RJ, Morrish AC, Meier SE, Hillard CJ, Gorzalka BB) J Neurochem 2008 Sep;106(6):2322-36 PMID: 18643796 PMCID: PMC2606621 SCOPUS ID: 2-s2.0-50849142856 07/23/2008       201 Citations
  • Mediation of cannabidiol anti-inflammation in the retina by equilibrative nucleoside transporter and A2A adenosine receptor. (Liou GI, Auchampach JA, Hillard CJ, Zhu G, Yousufzai B, Mian S, Khan S, Khalifa Y) Invest Ophthalmol Vis Sci 2008 Dec;49(12):5526-31 PMID: 18641283 PMCID: PMC2588644 SCOPUS ID: 2-s2.0-58149269741 07/22/2008       119 Citations
  • Adaptations in endocannabinoid signaling in response to repeated homotypic stress: a novel mechanism for stress habituation. (Patel S, Hillard CJ) Eur J Neurosci 2008 Jun;27(11):2821-9 PMID: 18588527 PMCID: PMC2593941 SCOPUS ID: 2-s2.0-45149111341 07/01/2008       136 Citations
  • Regulation of endocannabinoid signaling by stress: implications for stress-related affective disorders. (Gorzalka BB, Hill MN, Hillard CJ) Neurosci Biobehav Rev 2008 Aug;32(6):1152-60 PMID: 18433869 SCOPUS ID: 2-s2.0-45849113264 04/25/2008       179 Citations
  • Serum endocannabinoid content is altered in females with depressive disorders: a preliminary report. (Hill MN, Miller GE, Ho WS, Gorzalka BB, Hillard CJ) Pharmacopsychiatry 2008 Mar;41(2):48-53 PMID: 18311684 PMCID: PMC3422568 SCOPUS ID: 2-s2.0-41149130214 03/04/2008       227 Citations
  • Endocannabinoid signaling mediates cocaine-induced inhibitory synaptic plasticity in midbrain dopamine neurons. (Pan B, Hillard CJ, Liu QS) J Neurosci 2008 Feb 06;28(6):1385-97 PMID: 18256258 PMCID: PMC6671588 SCOPUS ID: 2-s2.0-38949143318 02/08/2008       125 Citations
  • Characterization of epoxyeicosatrienoic acid binding site in U937 membranes using a novel radiolabeled agonist, 20-125i-14,15-epoxyeicosa-8(Z)-enoic acid. (Yang W, Tuniki VR, Anjaiah S, Falck JR, Hillard CJ, Campbell WB) J Pharmacol Exp Ther 2008 Mar;324(3):1019-27 PMID: 18171909 SCOPUS ID: 2-s2.0-40849139451 01/04/2008       76 Citations
  • Glial expression of cannabinoid CB(2) receptors and fatty acid amide hydrolase are beta amyloid-linked events in Down's syndrome. (Núñez E, Benito C, Tolón RM, Hillard CJ, Griffin WS, Romero J) Neuroscience 2008 Jan 02;151(1):104-10 PMID: 18068305 SCOPUS ID: 2-s2.0-37849049077 12/11/2007       74 Citations
  • Prolonged glucocorticoid treatment decreases cannabinoid CB1 receptor density in the hippocampus. (Hill MN, Carrier EJ, Ho WS, Shi L, Patel S, Gorzalka BB, Hillard CJ) Hippocampus 2008;18(2):221-6 PMID: 18058925 SCOPUS ID: 2-s2.0-39849106394 12/07/2007       82 Citations
  • Brain uptake and utilization of fatty acids, lipids & lipoproteins: recommendations for future research. (Katz R, Hamilton JA, Pownall HJ, Deckelbaum RJ, Hillard CJ, Leboeuf RC, Watkins PA) J Mol Neurosci 2007 Sep;33(1):146-50 PMID: 17901559 SCOPUS ID: 2-s2.0-35348927453 09/29/2007       12 Citations
  • Studies of anandamide accumulation inhibitors in cerebellar granule neurons: comparison to inhibition of fatty acid amide hydrolase. (Hillard CJ, Shi L, Tuniki VR, Falck JR, Campbell WB) J Mol Neurosci 2007 Sep;33(1):18-24 PMID: 17901541 PMCID: PMC2248273 SCOPUS ID: 2-s2.0-35348851360 09/29/2007       30 Citations
  • Brain uptake and utilization of fatty acids, lipids and lipoproteins: application to neurological disorders. (Hamilton JA, Hillard CJ, Spector AA, Watkins PA) J Mol Neurosci 2007 Sep;33(1):2-11 PMID: 17901539 SCOPUS ID: 2-s2.0-35348879692 09/29/2007       105 Citations
  • Inhibition of 2-arachidonoylglycerol catabolism modulates vasoconstriction of rat middle cerebral artery by the thromboxane mimetic, U-46619. (Hillard CJ, Ho WS, Thompson J, Gauthier KM, Wheelock CE, Huang H, Hammock BD) Br J Pharmacol 2007 Nov;152(5):691-8 PMID: 17891162 PMCID: PMC2190024 SCOPUS ID: 2-s2.0-35649005473 09/25/2007       26 Citations
  • Effects of acute and repeated restraint stress on endocannabinoid content in the amygdala, ventral striatum, and medial prefrontal cortex in mice. (Rademacher DJ, Meier SE, Shi L, Ho WS, Jarrahian A, Hillard CJ) Neuropharmacology 2008 Jan;54(1):108-16 PMID: 17675104 SCOPUS ID: 2-s2.0-37349065102 08/07/2007       194 Citations
  • Electroconvulsive shock treatment differentially modulates cortical and subcortical endocannabinoid activity. (Hill MN, Barr AM, Ho WS, Carrier EJ, Gorzalka BB, Hillard CJ) J Neurochem 2007 Oct;103(1):47-56 PMID: 17561935 SCOPUS ID: 2-s2.0-34548648818 06/15/2007       45 Citations
  • Direct suppression of CNS autoimmune inflammation via the cannabinoid receptor CB1 on neurons and CB2 on autoreactive T cells. (Maresz K, Pryce G, Ponomarev ED, Marsicano G, Croxford JL, Shriver LP, Ledent C, Cheng X, Carrier EJ, Mann MK, Giovannoni G, Pertwee RG, Yamamura T, Buckley NE, Hillard CJ, Lutz B, Baker D, Dittel BN) Nat Med 2007 Apr;13(4):492-7 PMID: 17401376 SCOPUS ID: 2-s2.0-34147165471 04/03/2007       314 Citations
  • Cannabinoid CB1 and CB2 receptors and fatty acid amide hydrolase are specific markers of plaque cell subtypes in human multiple sclerosis. (Benito C, Romero JP, Tolón RM, Clemente D, Docagne F, Hillard CJ, Guaza C, Romero J) J Neurosci 2007 Feb 28;27(9):2396-402 PMID: 17329437 PMCID: PMC6673484 SCOPUS ID: 2-s2.0-33847420442 03/03/2007       232 Citations
  • Interactions between endocannabinoids and stress-induced decreased sensitivity to natural reward. (Rademacher DJ, Hillard CJ) Prog Neuropsychopharmacol Biol Psychiatry 2007 Apr 13;31(3):633-41 PMID: 17258369 PMCID: PMC1876712 SCOPUS ID: 2-s2.0-33947536045 01/30/2007       70 Citations
  • Involvement of the endocannabinoid system in the ability of long-term tricyclic antidepressant treatment to suppress stress-induced activation of the hypothalamic-pituitary-adrenal axis. (Hill MN, Ho WS, Sinopoli KJ, Viau V, Hillard CJ, Gorzalka BB) Neuropsychopharmacology 2006 Dec;31(12):2591-9 PMID: 16710317 SCOPUS ID: 2-s2.0-33748712399 05/20/2006       108 Citations
  • Inhibition of an equilibrative nucleoside transporter by cannabidiol: a mechanism of cannabinoid immunosuppression. (Carrier EJ, Auchampach JA, Hillard CJ) Proc Natl Acad Sci U S A 2006 May 16;103(20):7895-900 PMID: 16672367 PMCID: PMC1472541 SCOPUS ID: 2-s2.0-33646734889 05/05/2006       376 Citations
  • Modulators of endocannabinoid enzymic hydrolysis and membrane transport. (Ho WS, Hillard CJ) Handb Exp Pharmacol 2005(168):187-207 PMID: 16596775 SCOPUS ID: 2-s2.0-27644514002 04/07/2006       29 Citations
  • Pharmacological evaluation of cannabinoid receptor ligands in a mouse model of anxiety: further evidence for an anxiolytic role for endogenous cannabinoid signaling. (Patel S, Hillard CJ) J Pharmacol Exp Ther 2006 Jul;318(1):304-11 PMID: 16569753 SCOPUS ID: 2-s2.0-33745261630 03/30/2006       335 Citations
  • Fetomaternal cross talk in the placental vascular bed: control of coagulation by trophoblast cells. (Sood R, Kalloway S, Mast AE, Hillard CJ, Weiler H) Blood 2006 Apr 15;107(8):3173-80 PMID: 16380449 PMCID: PMC1895751 SCOPUS ID: 2-s2.0-33645746632 12/29/2005       88 Citations
  • Endocannabinoids in neuroimmunology and stress. (Carrier EJ, Patel S, Hillard CJ) Curr Drug Targets CNS Neurol Disord 2005 Dec;4(6):657-65 PMID: 16375683 SCOPUS ID: 2-s2.0-28944444774 12/27/2005       56 Citations
  • Chronic corticosterone treatment increases the endocannabinoid 2-arachidonylglycerol in the rat amygdala. (Hill MN, Ho WS, Meier SE, Gorzalka BB, Hillard CJ) Eur J Pharmacol 2005 Dec 28;528(1-3):99-102 PMID: 16324692 SCOPUS ID: 2-s2.0-28844445664 12/06/2005       35 Citations
  • Reticulocyte 15-lipoxygenase-I is important in acetylcholine-induced endothelium-dependent vasorelaxation in rabbit aorta. (Tang X, Holmes BB, Nithipatikom K, Hillard CJ, Kuhn H, Campbell WB) Arterioscler Thromb Vasc Biol 2006 Jan;26(1):78-84 PMID: 16239596 SCOPUS ID: 2-s2.0-33644824103 10/22/2005       29 Citations
  • Sepiapterin attenuates 1-methyl-4-phenylpyridinium-induced apoptosis in neuroblastoma cells transfected with neuronal NOS: role of tetrahydrobiopterin, nitric oxide, and proteasome activation. (Shang T, Kotamraju S, Zhao H, Kalivendi SV, Hillard CJ, Kalyanaraman B) Free Radic Biol Med 2005 Oct 15;39(8):1059-74 PMID: 16198233 SCOPUS ID: 2-s2.0-25144483746 10/04/2005       31 Citations
  • Modulation of the cannabinoid CB2 receptor in microglial cells in response to inflammatory stimuli. (Maresz K, Carrier EJ, Ponomarev ED, Hillard CJ, Dittel BN) J Neurochem 2005 Oct;95(2):437-45 PMID: 16086683 SCOPUS ID: 2-s2.0-26844448746 08/10/2005       407 Citations
  • Death-associated protein kinase as a sensor of mitochondrial membrane potential: role of lysosome in mitochondrial toxin-induced cell death. (Shang T, Joseph J, Hillard CJ, Kalyanaraman B) J Biol Chem 2005 Oct 14;280(41):34644-53 PMID: 16085644 SCOPUS ID: 2-s2.0-27144458235 08/09/2005       36 Citations
  • Lipids and drugs of abuse. (Hillard CJ) Life Sci 2005 Aug 19;77(14):1531-42 PMID: 15946699 SCOPUS ID: 2-s2.0-23044494981 06/11/2005       20 Citations
  • Accumulation of anandamide: evidence for cellular diversity. (Hillard CJ, Jarrahian A) Neuropharmacology 2005 Jun;48(8):1072-8 PMID: 15910883 SCOPUS ID: 2-s2.0-19444375706 05/25/2005       34 Citations
  • Effects of endocannabinoids on discharge of baroreceptive NTS neurons. (Seagard JL, Hopp FA, Hillard CJ, Dean C) Neurosci Lett 2005 Jun 24;381(3):334-9 PMID: 15896495 SCOPUS ID: 2-s2.0-19344369593 05/18/2005       23 Citations
  • Inhibition of restraint stress-induced neural and behavioural activation by endogenous cannabinoid signalling. (Patel S, Roelke CT, Rademacher DJ, Hillard CJ) Eur J Neurosci 2005 Feb;21(4):1057-69 PMID: 15787710 SCOPUS ID: 2-s2.0-16244398653 03/25/2005       256 Citations
  • A glial endogenous cannabinoid system is upregulated in the brains of macaques with simian immunodeficiency virus-induced encephalitis. (Benito C, Kim WK, Chavarría I, Hillard CJ, Mackie K, Tolón RM, Williams K, Romero J) J Neurosci 2005 Mar 09;25(10):2530-6 PMID: 15758162 PMCID: PMC6725174 SCOPUS ID: 2-s2.0-14944367009 03/11/2005       140 Citations
  • U-46619 but not serotonin increases endocannabinoid content in middle cerebral artery: evidence for functional relevance. (Rademacher DJ, Patel S, Ho WS, Savoie AM, Rusch NJ, Gauthier KM, Hillard CJ) Am J Physiol Heart Circ Physiol 2005 Jun;288(6):H2694-701 PMID: 15695564 SCOPUS ID: 2-s2.0-19344367770 02/08/2005       23 Citations
  • Characterization of phospholipase activity of the Pseudomonas aeruginosa type III cytotoxin, ExoU. (Sato H, Feix JB, Hillard CJ, Frank DW) J Bacteriol 2005 Feb;187(3):1192-5 PMID: 15659695 PMCID: PMC545705 SCOPUS ID: 2-s2.0-13244295376 01/22/2005       53 Citations
  • 2-arachidonoylglycerol: a novel inhibitor of androgen-independent prostate cancer cell invasion. (Nithipatikom K, Endsley MP, Isbell MA, Falck JR, Iwamoto Y, Hillard CJ, Campbell WB) Cancer Res 2004 Dec 15;64(24):8826-30 PMID: 15604240 SCOPUS ID: 2-s2.0-10844265493 12/18/2004       122 Citations
  • The postmortal accumulation of brain N-arachidonylethanolamine (anandamide) is dependent upon fatty acid amide hydrolase activity. (Patel S, Carrier EJ, Ho WS, Rademacher DJ, Cunningham S, Reddy DS, Falck JR, Cravatt BF, Hillard CJ) J Lipid Res 2005 Feb;46(2):342-9 PMID: 15576840 SCOPUS ID: 2-s2.0-13944272187 12/04/2004       115 Citations
  • Anandamide content is increased and CB1 cannabinoid receptor blockade is protective during transient, focal cerebral ischemia. (Muthian S, Rademacher DJ, Roelke CT, Gross GJ, Hillard CJ) Neuroscience 2004;129(3):743-50 PMID: 15541895 SCOPUS ID: 2-s2.0-8444250235 11/16/2004       127 Citations
  • Endothelium-derived 2-arachidonylglycerol: an intermediate in vasodilatory eicosanoid release in bovine coronary arteries. (Gauthier KM, Baewer DV, Hittner S, Hillard CJ, Nithipatikom K, Reddy DS, Falck JR, Campbell WB) Am J Physiol Heart Circ Physiol 2005 Mar;288(3):H1344-51 PMID: 15528233 SCOPUS ID: 2-s2.0-13944262157 11/06/2004       64 Citations
  • Waterborne lead exposure affects brain endocannabinoid content in male but not female fathead minnows (Pimephales promelas). (Rademacher DJ, Weber DN, Hillard CJ) Neurotoxicology 2005 Jan;26(1):9-15 PMID: 15527869 SCOPUS ID: 2-s2.0-7444252224 11/06/2004       16 Citations
  • Downregulation of endocannabinoid signaling in the hippocampus following chronic unpredictable stress. (Hill MN, Patel S, Carrier EJ, Rademacher DJ, Ormerod BK, Hillard CJ, Gorzalka BB) Neuropsychopharmacology 2005 Mar;30(3):508-15 PMID: 15525997 SCOPUS ID: 2-s2.0-13944280321 11/05/2004       306 Citations
  • Spatial correlations of laminar BOLD and CBV responses to rat whisker stimulation with neuronal activity localized by Fos expression. (Lu H, Patel S, Luo F, Li SJ, Hillard CJ, Ward BD, Hyde JS) Magn Reson Med 2004 Nov;52(5):1060-8 PMID: 15508149 SCOPUS ID: 2-s2.0-7544245944 10/28/2004       101 Citations
  • Endocannabinoid signaling negatively modulates stress-induced activation of the hypothalamic-pituitary-adrenal axis. (Patel S, Roelke CT, Rademacher DJ, Cullinan WE, Hillard CJ) Endocrinology 2004 Dec;145(12):5431-8 PMID: 15331569 SCOPUS ID: 2-s2.0-9444277292 08/28/2004       405 Citations
  • Synergistic interactions between cannabinoids and environmental stress in the activation of the central amygdala. (Patel S, Cravatt BF, Hillard CJ) Neuropsychopharmacology 2005 Mar;30(3):497-507 PMID: 15280883 SCOPUS ID: 2-s2.0-13944278876 07/29/2004       137 Citations
  • Dendritically released transmitters cooperate via autocrine and retrograde actions to inhibit afferent excitation in rat brain. (Hirasawa M, Schwab Y, Natah S, Hillard CJ, Mackie K, Sharkey KA, Pittman QJ) J Physiol 2004 Sep 01;559(Pt 2):611-24 PMID: 15254151 PMCID: PMC1665137 SCOPUS ID: 2-s2.0-4644280012 07/16/2004       120 Citations
  • Chronic administration of nitric oxide reduces angiotensin II receptor type 1 expression and aldosterone synthesis in zona glomerulosa cells. (Nithipatikom K, Holmes BB, McCoy MJ, Hillard CJ, Campbell WB) Am J Physiol Endocrinol Metab 2004 Nov;287(5):E820-7 PMID: 15198935 SCOPUS ID: 2-s2.0-6044274619 06/17/2004       11 Citations
  • Cultured rat microglial cells synthesize the endocannabinoid 2-arachidonylglycerol, which increases proliferation via a CB2 receptor-dependent mechanism. (Carrier EJ, Kearn CS, Barkmeier AJ, Breese NM, Yang W, Nithipatikom K, Pfister SL, Campbell WB, Hillard CJ) Mol Pharmacol 2004 Apr;65(4):999-1007 PMID: 15044630 SCOPUS ID: 2-s2.0-1842428537 03/27/2004       303 Citations
  • Production of hydroxyeicosatetraenoic acids and prostaglandins by a novel rat microglial cell line. (Rademacher DJ, Kearn CS, Carrier EJ, Patel S, Delgado MA, Barkmeier A, Klick DE, Breese NM, Pfister SL, Nithipatikom K, Campbell WB, Hillard CJ) J Neuroimmunol 2004 Apr;149(1-2):130-41 PMID: 15020073 SCOPUS ID: 2-s2.0-12144287853 03/17/2004       7 Citations
  • 1-Methyl-4-phenylpyridinium-induced apoptosis in cerebellar granule neurons is mediated by transferrin receptor iron-dependent depletion of tetrahydrobiopterin and neuronal nitric-oxide synthase-derived superoxide. (Shang T, Kotamraju S, Kalivendi SV, Hillard CJ, Kalyanaraman B) J Biol Chem 2004 Apr 30;279(18):19099-112 PMID: 14752097 SCOPUS ID: 2-s2.0-2442504779 01/31/2004       57 Citations
  • Alpha-synuclein up-regulation and aggregation during MPP+-induced apoptosis in neuroblastoma cells: intermediacy of transferrin receptor iron and hydrogen peroxide. (Kalivendi SV, Cunningham S, Kotamraju S, Joseph J, Hillard CJ, Kalyanaraman B) J Biol Chem 2004 Apr 09;279(15):15240-7 PMID: 14742448 SCOPUS ID: 2-s2.0-2442494278 01/27/2004       122 Citations
  • Characterization of an anandamide degradation system in prostate epithelial PC-3 cells: synthesis of new transporter inhibitors as tools for this study. (Ruiz-Llorente L, Ortega-Gutiérrez S, Viso A, Sánchez MG, Sánchez AM, Fernández C, Ramos JA, Hillard C, Lasunción MA, López-Rodríguez ML, Díaz-Laviada I) Br J Pharmacol 2004 Feb;141(3):457-67 PMID: 14718261 PMCID: PMC1574211 SCOPUS ID: 2-s2.0-10744227377 01/14/2004       38 Citations
  • Cannabinoid CB2 receptors and fatty acid amide hydrolase are selectively overexpressed in neuritic plaque-associated glia in Alzheimer's disease brains. (Benito C, Núñez E, Tolón RM, Carrier EJ, Rábano A, Hillard CJ, Romero J) J Neurosci 2003 Dec 03;23(35):11136-41 PMID: 14657172 PMCID: PMC6741043 SCOPUS ID: 2-s2.0-0348010292 12/06/2003       548 Citations
  • Anandamide content and interaction of endocannabinoid/GABA modulatory effects in the NTS on baroreflex-evoked sympathoinhibition. (Seagard JL, Dean C, Patel S, Rademacher DJ, Hopp FA, Schmeling WT, Hillard CJ) Am J Physiol Heart Circ Physiol 2004 Mar;286(3):H992-1000 PMID: 14615281 SCOPUS ID: 2-s2.0-1342304201 11/15/2003       58 Citations
  • Cellular accumulation of anandamide: consensus and controversy. (Hillard CJ, Jarrahian A) Br J Pharmacol 2003 Nov;140(5):802-8 PMID: 12970089 PMCID: PMC1574088 SCOPUS ID: 2-s2.0-0344441315 09/13/2003       199 Citations
  • The general anesthetic propofol increases brain N-arachidonylethanolamine (anandamide) content and inhibits fatty acid amide hydrolase. (Patel S, Wohlfeil ER, Rademacher DJ, Carrier EJ, Perry LJ, Kundu A, Falck JR, Nithipatikom K, Campbell WB, Hillard CJ) Br J Pharmacol 2003 Jul;139(5):1005-13 PMID: 12839875 PMCID: PMC1573928 SCOPUS ID: 2-s2.0-10744224124 07/04/2003       125 Citations
  • Differential regulation of the endocannabinoids anandamide and 2-arachidonylglycerol within the limbic forebrain by dopamine receptor activity. (Patel S, Rademacher DJ, Hillard CJ) J Pharmacol Exp Ther 2003 Sep;306(3):880-8 PMID: 12808005 SCOPUS ID: 2-s2.0-0041932370 06/17/2003       137 Citations
  • The mechanism of action of the Pseudomonas aeruginosa-encoded type III cytotoxin, ExoU. (Sato H, Frank DW, Hillard CJ, Feix JB, Pankhaniya RR, Moriyama K, Finck-Barbançon V, Buchaklian A, Lei M, Long RM, Wiener-Kronish J, Sawa T) EMBO J 2003 Jun 16;22(12):2959-69 PMID: 12805211 PMCID: PMC162142 SCOPUS ID: 2-s2.0-0038376087 06/14/2003       283 Citations
  • Hemisynthesis and preliminary evaluation of novel endocannabinoid analogues. (El Fangour S, Balas L, Rossi JC, Fedenyuk A, Gretskaya N, Bobrov M, Bezuglov V, Hillard CJ, Durand T) Bioorg Med Chem Lett 2003 Jun 16;13(12):1977-80 PMID: 12781177 SCOPUS ID: 2-s2.0-0038440634 06/05/2003       7 Citations
  • 1-Methyl-4-phenylpyridinium accumulates in cerebellar granule neurons via organic cation transporter 3. (Shang T, Uihlein AV, Van Asten J, Kalyanaraman B, Hillard CJ) J Neurochem 2003 Apr;85(2):358-67 PMID: 12675912 SCOPUS ID: 2-s2.0-0344406174 04/05/2003       72 Citations
  • Cannabinoid-induced Fos expression within A10 dopaminergic neurons. (Patel S, Hillard CJ) Brain Res 2003 Feb 14;963(1-2):15-25 PMID: 12560108 SCOPUS ID: 2-s2.0-0037435933 02/01/2003       57 Citations
  • 1-Methyl-4-phenylpyridinium (MPP+)-induced apoptosis and mitochondrial oxidant generation: role of transferrin-receptor-dependent iron and hydrogen peroxide. (Kalivendi SV, Kotamraju S, Cunningham S, Shang T, Hillard CJ, Kalyanaraman B) Biochem J 2003 Apr 01;371(Pt 1):151-64 PMID: 12523938 PMCID: PMC1223270 SCOPUS ID: 2-s2.0-0037394420 01/14/2003       115 Citations
  • Microinjection of a cannabinoid receptor antagonist into the NTS increases baroreflex duration in dogs. (Rademacher DJ, Patel S, Hopp FA, Dean C, Hillard CJ, Seagard JL) Am J Physiol Heart Circ Physiol 2003 May;284(5):H1570-6 PMID: 12521935 SCOPUS ID: 2-s2.0-0037405166 01/11/2003       31 Citations
  • The CB1 receptor antagonist SR141716 enhances stimulus-induced activation of the primary somatosensory cortex of the rat. (Patel S, Gerrits R, Muthian S, Greene AS, Hillard CJ) Neurosci Lett 2002 Dec 25;335(2):95-8 PMID: 12459507 SCOPUS ID: 2-s2.0-0037176194 12/03/2002       15 Citations
  • Emesis, appetite, and endocannabinoids. (Inui A) Gastroenterology 2002 Aug;123(2):655; author reply 655-6 PMID: 12145832 SCOPUS ID: 2-s2.0-0036320664 07/30/2002    
  • Fatty acid amide hydrolase localization in the human central nervous system: an immunohistochemical study. (Romero J, Hillard CJ, Calero M, Rábano A) Brain Res Mol Brain Res 2002 Apr 30;100(1-2):85-93 PMID: 12008024 SCOPUS ID: 2-s2.0-0037197799 05/15/2002       73 Citations
  • Emesis, appetite, and endocannabinoids (Van Sickle M, Davison J, Sharkey K, Mackie K, Hillard C) Gastroenterology 2002;123(2):655-656 SCOPUS ID: 2-s2.0-85019984247 01/01/2002       4 Citations
  • Cannabinoid-receptor-independent cell signalling by N-acylethanolamines. (Berdyshev EV, Schmid PC, Krebsbach RJ, Hillard CJ, Huang C, Chen N, Dong Z, Schmid HH) Biochem J 2001 Nov 15;360(Pt 1):67-75 PMID: 11695993 PMCID: PMC1222203 SCOPUS ID: 2-s2.0-0035890677 11/07/2001       71 Citations
  • Cannabinoid receptor agonists inhibit depolarization-induced calcium influx in cerebellar granule neurons. (Nogueron MI, Porgilsson B, Schneider WE, Stucky CL, Hillard CJ) J Neurochem 2001 Oct;79(2):371-81 PMID: 11677265 SCOPUS ID: 2-s2.0-0034775812 10/26/2001       41 Citations
  • Cannabinoids inhibit emesis through CB1 receptors in the brainstem of the ferret. (Van Sickle MD, Oland LD, Ho W, Hillard CJ, Mackie K, Davison JS, Sharkey KA) Gastroenterology 2001 Oct;121(4):767-74 PMID: 11606489 SCOPUS ID: 2-s2.0-0034791999 10/19/2001       208 Citations
  • Cannabinoid CB(1) receptor agonists produce cerebellar dysfunction in mice. (Patel S, Hillard CJ) J Pharmacol Exp Ther 2001 May;297(2):629-37 PMID: 11303052 SCOPUS ID: 2-s2.0-0035037811 04/17/2001       76 Citations
  • The uptake by cells of 2-arachidonoylglycerol, an endogenous agonist of cannabinoid receptors. (Bisogno T, MacCarrone M, De Petrocellis L, Jarrahian A, Finazzi-Agrò A, Hillard C, Di Marzo V) Eur J Biochem 2001 Apr;268(7):1982-9 PMID: 11277920 SCOPUS ID: 2-s2.0-0034850220 03/30/2001       137 Citations
  • Endothelium-independent, ouabain-sensitive relaxation of bovine coronary arteries by EETs. (Pratt PF, Li P, Hillard CJ, Kurian J, Campbell WB) Am J Physiol Heart Circ Physiol 2001 Mar;280(3):H1113-21 PMID: 11179054 SCOPUS ID: 2-s2.0-0034975475 02/17/2001       52 Citations
  • The cellular uptake of anandamide is coupled to its breakdown by fatty-acid amide hydrolase. (Deutsch DG, Glaser ST, Howell JM, Kunz JS, Puffenbarger RA, Hillard CJ, Abumrad N) J Biol Chem 2001 Mar 09;276(10):6967-73 PMID: 11118429 SCOPUS ID: 2-s2.0-0035831508 12/19/2000       198 Citations
  • The movement of N-arachidonoylethanolamine (anandamide) across cellular membranes. (Hillard CJ, Jarrahian A) Chem Phys Lipids 2000 Nov;108(1-2):123-34 PMID: 11106786 SCOPUS ID: 2-s2.0-0033666960 12/07/2000       173 Citations
  • Inhibition of small intestinal secretion by cannabinoids is CB1 receptor-mediated in rats. (Tyler K, Hillard CJ, Greenwood-Van Meerveld B) Eur J Pharmacol 2000 Dec 08;409(2):207-11 PMID: 11104836 SCOPUS ID: 2-s2.0-0034624257 12/06/2000       57 Citations
  • Endocannabinoids and vascular function. (Hillard CJ) J Pharmacol Exp Ther 2000 Jul;294(1):27-32 PMID: 10871291 SCOPUS ID: 2-s2.0-0033917648 06/28/2000       165 Citations
  • Structure-activity relationships among N-arachidonylethanolamine (Anandamide) head group analogues for the anandamide transporter. (Jarrahian A, Manna S, Edgemond WS, Campbell WB, Hillard CJ) J Neurochem 2000 Jun;74(6):2597-606 PMID: 10820223 SCOPUS ID: 2-s2.0-0034070409 05/23/2000       134 Citations
  • Biochemistry and pharmacology of the endocannabinoids arachidonylethanolamide and 2-arachidonylglycerol. (Hillard CJ) Prostaglandins Other Lipid Mediat 2000 Apr;61(1-2):3-18 PMID: 10785538 SCOPUS ID: 2-s2.0-0033998951 04/29/2000       212 Citations
  • Synthesis and characterization of a fluorescent substrate for the N-arachidonoylethanolamine (anandamide) transmembrane carrier. (Muthian S, Nithipatikom K, Campbell WB, Hillard CJ) J Pharmacol Exp Ther 2000 Apr;293(1):289-95 PMID: 10734181 SCOPUS ID: 2-s2.0-0034087481 03/29/2000       33 Citations
  • Cannabinoid CB1 receptor of cat cerebral arterial muscle functions to inhibit L-type Ca2+ channel current (Gebremedhin D, Lange AR, Campbell WB, Hillard CJ, Harder DR) American Journal of Physiology 1999;276(6 PART 2) SCOPUS ID: 2-s2.0-33746492252 12/01/1999       61 Citations
  • Effects of CB(1) cannabinoid receptor activation on cerebellar granule cell nitric oxide synthase activity. (Hillard CJ, Muthian S, Kearn CS) FEBS Lett 1999 Oct 08;459(2):277-81 PMID: 10518035 SCOPUS ID: 2-s2.0-0032830327 10/13/1999       92 Citations
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  • Relationships between ligand affinities for the cerebellar cannabinoid receptor CB1 and the induction of GDP/GTP exchange. (Kearn CS, Greenberg MJ, DiCamelli R, Kurzawa K, Hillard CJ) J Neurochem 1999 Jun;72(6):2379-87 PMID: 10349847 SCOPUS ID: 2-s2.0-0032973339 06/01/1999       106 Citations
  • Synthesis and characterization of potent and selective agonists of the neuronal cannabinoid receptor (CB1). (Hillard CJ, Manna S, Greenberg MJ, DiCamelli R, Ross RA, Stevenson LA, Murphy V, Pertwee RG, Campbell WB) J Pharmacol Exp Ther 1999 Jun;289(3):1427-33 PMID: 10336536 SCOPUS ID: 2-s2.0-0033060910 05/21/1999       325 Citations
  • Fatty acid amide hydrolase is located preferentially in large neurons in the rat central nervous system as revealed by immunohistochemistry. (Tsou K, Nogueron MI, Muthian S, Sañudo-Pena MC, Hillard CJ, Deutsch DG, Walker JM) Neurosci Lett 1998 Oct 02;254(3):137-40 PMID: 10214976 SCOPUS ID: 2-s2.0-0032476070 04/24/1999       225 Citations
  • Human platelets and polymorphonuclear leukocytes synthesize oxygenated derivatives of arachidonylethanolamide (anandamide): their affinities for cannabinoid receptors and pathways of inactivation. (Edgemond WS, Hillard CJ, Falck JR, Kearn CS, Campbell WB) Mol Pharmacol 1998 Jul;54(1):180-8 PMID: 9658204 SCOPUS ID: 2-s2.0-0031820286 07/11/1998       115 Citations
  • Synthesis and characterization of diazomethylarachidonyl ketone: an irreversible inhibitor of N-arachidonylethanolamine amidohydrolase. (Edgemond WS, Greenberg MJ, McGinley PJ, Muthian S, Campbell WB, Hillard CJ) J Pharmacol Exp Ther 1998 Jul;286(1):184-90 PMID: 9655859 SCOPUS ID: 2-s2.0-0031847458 07/10/1998       45 Citations
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  • Arachidonylethanolamide (anandamide) binds with low affinity to dihydropyridine binding sites in brain membranes. (Jarrahian A, Hillard CJ) Prostaglandins Leukot Essent Fatty Acids 1997 Dec;57(6):551-4 PMID: 9431821 SCOPUS ID: 2-s2.0-0030827460 02/07/1998       24 Citations
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  • The role of nitric oxide in the cerebrovascular response to hypercapnia. (Smith JJ, Lee JG, Hudetz AG, Hillard CJ, Bosnjak ZJ, Kampine JP) Anesth Analg 1997 Feb;84(2):363-9 PMID: 9024030 SCOPUS ID: 2-s2.0-0031057266 02/01/1997       23 Citations
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  • Immunocytes and abnormal gastrointestinal motor activity during ileitis in dogs. (Jouët P, Sarna SK, Singaram C, Ryan RP, Hillard CJ, Telford GL, Fink J, Henderson JD) Am J Physiol 1995 Dec;269(6 Pt 1):G913-24 PMID: 8572223 SCOPUS ID: 2-s2.0-0029616583 12/01/1995       39 Citations
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  • Laser-Doppler measurement of the effects of halothane and isoflurane on the cerebrovascular CO2 response in the rat. (Lee JG, Smith JJ, Hudetz AG, Hillard CJ, Bosnjak ZJ, Kampine JP) Anesth Analg 1995 Apr;80(4):696-702 PMID: 7893020 SCOPUS ID: 2-s2.0-0028951335 04/01/1995       28 Citations
  • The binding of novel phenolic derivatives of anandamide to brain cannabinoid receptors. (Edgemond WS, Campbell WB, Hillard CJ) Prostaglandins Leukot Essent Fatty Acids 1995;52(2-3):83-6 PMID: 7784462 SCOPUS ID: 2-s2.0-0028800749 02/01/1995       29 Citations
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  • The effects of halothane and isoflurane on cerebrocortical microcirculation and autoregulation as assessed by laser-Doppler flowmetry. (Lee JG, Hudetz AG, Smith JJ, Hillard CJ, Bosnjak ZJ, Kampine JP) Anesth Analg 1994 Jul;79(1):58-65 PMID: 8010455 SCOPUS ID: 2-s2.0-0028303715 07/01/1994       56 Citations
  • Decreased adrenal medullary catecholamine release in spontaneously diabetic BB-Wistar rats. Role of hypoglycemia. (Wilke RA, Hillard CJ) Diabetes 1994 May;43(5):724-9 PMID: 8168651 SCOPUS ID: 2-s2.0-0028278880 05/01/1994       22 Citations
  • In vitro activation of brain protein kinase C by the cannabinoids. (Hillard CJ, Auchampach JA) Biochim Biophys Acta 1994 Jan 13;1220(2):163-70 PMID: 8312360 SCOPUS ID: 2-s2.0-0028012276 01/13/1994       30 Citations
  • Decreased catecholamine secretion from the adrenal medullae of chronically diabetic BB-Wistar rats. (Wilke RA, Riley DA, Lelkes PI, Hillard CJ) Diabetes 1993 Jun;42(6):862-8 PMID: 8495810 SCOPUS ID: 2-s2.0-0027193761 06/01/1993       18 Citations
  • Effects of chronic nicotine treatment on the accumulation of [3H]tetraphenylphosphonium by cerebral cortical synaptosomes. (Hillard CJ, Pounds JJ) J Neurochem 1993 Feb;60(2):687-95 PMID: 8419544 SCOPUS ID: 2-s2.0-0027497595 02/01/1993       12 Citations
  • Role of guanylate cyclase-cGMP systems in halothane-induced vasodilation in canine cerebral arteries. (Eskinder H, Hillard CJ, Flynn N, Bosnjak ZJ, Kampine JP) Anesthesiology 1992 Sep;77(3):482-7 PMID: 1355637 SCOPUS ID: 2-s2.0-0026786912 09/01/1992       27 Citations
  • Nicotine-induced depolarization of cerebral cortical synaptosomes is dependent upon sodium. (Hillard CJ) Neuropharmacology 1992 Sep;31(9):909-14 PMID: 1436397 SCOPUS ID: 2-s2.0-0026649252 09/01/1992       4 Citations
  • [3H]tetraphenylphosphonium accumulation in cerebral cortical synaptosomes as a measure of nicotine-induced changes in membrane potential. (Hillard CJ, Pounds JJ) J Pharmacol Exp Ther 1991 Dec;259(3):1118-23 PMID: 1762066 SCOPUS ID: 2-s2.0-0026357502 12/01/1991       8 Citations
  • Studies of the effect of nicotine on synaptosomal calcium accumulation using FURA-2. (Hillard CJ, Graf WK) NIDA Res Monogr 1990;105:331-2 PMID: 1876032 SCOPUS ID: 2-s2.0-0025569911 01/01/1991       6 Citations
  • Comparison of the vasodilation and inhibition of phosphatidylinositol hydrolysis produced by KT-362 and TMB-8 in canine femoral artery (Hillard CJ, Hruz PW, Gross GJ) Journal of Vascular Medicine and Biology 1991;3(1):1-4 SCOPUS ID: 2-s2.0-0025822876 01/01/1991    
  • Studies of the role of membrane lipid order in the effects of delta 9-tetrahydrocannabinol on adenylate cyclase activation in heart. (Hillard CJ, Pounds JJ, Boyer DR, Bloom AS) J Pharmacol Exp Ther 1990 Mar;252(3):1075-82 PMID: 2156989 SCOPUS ID: 2-s2.0-0025257436 03/01/1990       26 Citations
  • Effect of KT-362, a putative intracellular calcium antagonist, on norepinephrine-induced contractions and inositol monophosphate accumulation in canine femoral artery. (Eskinder H, Hillard CJ, Wilke RA, Gross GJ) J Cardiovasc Pharmacol 1989 Mar;13(3):502-7 PMID: 2471898 SCOPUS ID: 2-s2.0-0024582073 03/01/1989       16 Citations
  • Alpha adrenoceptor subtypes and receptor reserve in human versus canine saphenous vein: sensitivity to blockade by nitroglycerin. (Eskinder H, Hillard CJ, Olinger GN, Christensen CW, Baker JE, Warltier DC, Gross GJ) J Pharmacol Exp Ther 1988 Dec;247(3):941-8 PMID: 2905005 SCOPUS ID: 2-s2.0-0024269976 12/01/1988       11 Citations
  • Effects of delta 9-tetrahydrocannabinol on glucagon receptor coupling to adenylate cyclase in rat liver plasma membranes. (Hillard CJ, Bloom AS, Houslay MD) Biochem Pharmacol 1986 Aug 15;35(16):2797-803 PMID: 3017362 SCOPUS ID: 2-s2.0-0022505707 08/15/1986       17 Citations
  • Effects of the cannabinoids on physical properties of brain membranes and phospholipid vesicles: fluorescence studies. (Hillard CJ, Harris RA, Bloom AS) J Pharmacol Exp Ther 1985 Mar;232(3):579-88 PMID: 2983062 SCOPUS ID: 2-s2.0-0021929098 03/01/1985       95 Citations
  • The effects of delta 9-tetrahydrocannabinol on serum thyrotropin levels in the rat. (Hillard CJ, Farber NE, Hagen TC, Bloom AS) Pharmacol Biochem Behav 1984 Apr;20(4):547-50 PMID: 6328543 SCOPUS ID: 2-s2.0-0021344416 04/01/1984       30 Citations
  • The effects of cannabinoids on fluidity of brain synaptic membranes (Hillard CJ, Harris RA, Bloom AS) Federation Proceedings 1984;43(4) SCOPUS ID: 2-s2.0-0021137132 01/01/1984    
  • Possible role of prostaglandins in the effects of the cannabinoids on adenylate cyclase activity. (Hillard CJ, Bloom AS) Eur J Pharmacol 1983 Jul 15;91(1):21-7 PMID: 6311573 SCOPUS ID: 2-s2.0-0020595620 07/15/1983       21 Citations
  • delta 9-Tetrahydrocannabinol-induced changes in beta-adrenergic receptor binding in mouse cerebral cortex. (Hillard CJ, Bloom AS) Brain Res 1982 Mar 11;235(2):370-7 PMID: 6329417 SCOPUS ID: 2-s2.0-0020059703 03/11/1982       28 Citations
    • Last update: 04/07/2024