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Olena Isaeva PhD

Olena Isaeva PhD profile photo picture

Assistant Professor

Institution: Medical College of Wisconsin
Department: Cell Biology, Neurobiology and Anatomy
Program: Administration

Member of the Cancer Center


I am willing to collaborate on research projects.
I am willing to mentor a junior faculty member.

View Curriculum Vitae

Research Areas of Interest

  • Calcium Signaling
  • Epilepsy
  • Hearing Disorders
  • Hippocampus
  • Hypertension
  • Ion Channels
  • Kidney
  • Pain
  • Sensation Disorders

    • Research Experience

  • Behavior, Animal
  • Electroencephalography
  • Functional Neuroimaging
  • Hearing Tests
  • Patch-Clamp Techniques

    • Publications (75)

  • Increased keratinocyte activity and PIEZO1 signaling contribute to paclitaxel-induced mechanical hypersensitivity. (Mikesell AR, Isaeva E, Schulte ML, Menzel AD, Sriram A, Prahl MM, Shin SM, Sadler KE, Yu H, Stucky CL) Sci Transl Med 2024 Dec 11;16(777):eadn5629 PMID: 39661703 SCOPUS ID: 2-s2.0-85211969507 12/11/2024       2 Citations
  • Inhibition of mTORC2 promotes natriuresis in Dahl salt-sensitive rats via the decrease of NCC and ENaC activity. (Yang C, Isaeva E, Shimada S, Kurth T, Stumpf M, Zheleznova NN, Staruschenko A, Dash RK, Cowley AW Jr) Am J Physiol Renal Physiol 2024 Sep 01;327(3):F435-F449 PMID: 38779754 PMCID: PMC11460535 SCOPUS ID: 2-s2.0-85201902774 05/23/2024    
  • Fabry disease Schwann cells release p11 to induce sensory neuron hyperactivity. (Waltz TB, Chao D, Prodoehl EK, Enders JD, Ehlers VL, Dharanikota BS, Dahms NM, Isaeva E, Hogan QH, Pan B, Stucky CL) JCI Insight 2024 Mar 07;9(8) PMID: 38646936 PMCID: PMC11141882 SCOPUS ID: 2-s2.0-85191335156 04/22/2024       1 Citation
  • Sickle cell disease iPSC-derived sensory neurons exhibit increased excitability and sensitization to patient plasma. (Allison RL, Welby E, Ehlers V, Burand A, Isaeva O, Nieves Torres D, Highland J, Brandow AM, Stucky CL, Ebert AD) Blood 2024 May 16;143(20):2037-2052 PMID: 38427938 PMCID: PMC11143522 SCOPUS ID: 2-s2.0-85189689054 03/01/2024       2 Citations
  • Keratinocyte Piezo1 drives paclitaxel-induced mechanical hypersensitivity. (Mikesell AR, Isaeva E, Schulte ML, Menzel AD, Sriram A, Prahl MM, Shin SM, Sadler KE, Yu H, Stucky CL) bioRxiv 2023 Dec 13 PMID: 38168305 PMCID: PMC10760029 01/04/2024    
  • Protease-Activated Receptor 1-Mediated Damage of Podocytes in Diabetic Nephropathy. (Bohovyk R, Khedr S, Levchenko V, Stefanenko M, Semenikhina M, Kravtsova O, Isaeva E, Geurts AM, Klemens CA, Palygin O, Staruschenko A) Diabetes 2023 Dec 01;72(12):1795-1808 PMID: 37722138 PMCID: PMC10658073 SCOPUS ID: 2-s2.0-85176576178 09/18/2023       11 Citations
  • Consequences of adolescent social isolation on behavior and synaptic plasticity in the dorsal and ventral hippocampus in male Wistar rats. (Nikolaienko O, Klymenko M, Isaeva E) Neurol Res 2023 Dec;45(12):1152-1160 PMID: 37698124 SCOPUS ID: 2-s2.0-85170670600 09/12/2023       4 Citations
  • Schwann cell release of p11 induces sensory neuron hyperactivity in Fabry disease. (Waltz TB, Chao D, Prodoehl EK, Ehlers VL, Dharanikota BS, Dahms NM, Isaeva E, Hogan QH, Pan B, Stucky CL) bioRxiv 2023 May 28 PMID: 37292928 PMCID: PMC10245981 06/09/2023    
  • Spinal muscular atrophy-like phenotype in a mouse model of acid ceramidase deficiency. (Nagree MS, Rybova J, Kleynerman A, Ahrenhoerster CJ, Saville JT, Xu T, Bachochin M, McKillop WM, Lawlor MW, Pshezhetsky AV, Isaeva O, Budde MD, Fuller M, Medin JA) Commun Biol 2023 May 25;6(1):560 PMID: 37231125 PMCID: PMC10212955 SCOPUS ID: 2-s2.0-85160222255 05/26/2023       8 Citations
  • The small GTPase regulatory protein Rac1 drives podocyte injury independent of cationic channel protein TRPC5. (Polat OK, Isaeva E, Sudhini YR, Knott B, Zhu K, Noben M, Suresh Kumar V, Endlich N, Mangos S, Reddy TV, Samelko B, Wei C, Altintas MM, Dryer SE, Sever S, Staruschenko A, Reiser J) Kidney Int 2023 Jun;103(6):1056-1062 PMID: 36750145 PMCID: PMC10200725 SCOPUS ID: 2-s2.0-85148731140 02/08/2023       13 Citations
  • Use the force, fluke: Ligand-independent gating of Schistosoma mansoni ion channel TRPMPZQ. (Chulkov EG, Isaeva E, Stucky CL, Marchant JS) Int J Parasitol 2023 Jul;53(8):427-434 PMID: 36610555 PMCID: PMC10258140 SCOPUS ID: 2-s2.0-85146298174 01/08/2023       3 Citations
  • Pharmacological blockade of neuraminidase activity does not affect paired-pulse plasticity in hippocampal CA3-to-CA1 network (Savotchenko AV, Isaeva EV, Isaev DS) Biopolymers and Cell 2023;39(2):146-151 SCOPUS ID: 2-s2.0-85166955495 01/01/2023    
  • EFFECT OF NEURAMINIDASE INHIBITION ON VARIATION OF FIELD EXTRACELLULAR POTENTIALS IN RAT HIPPOCAMPAL NETWORK (Savotchenko AV, Isaeva EV, Isaev DS) Fiziologichnyi Zhurnal 2023;69(4):40-44 SCOPUS ID: 2-s2.0-85169801582 01/01/2023    
  • Modulation of P2X4 receptor activity by ivermectin and 5-BDBD has no effect on the development of ARPKD in PCK rats. (Xu B, Nikolaienko O, Levchenko V, Choubey AS, Isaeva E, Staruschenko A, Palygin O) Physiol Rep 2022 Nov;10(21):e15510 PMID: 36353932 PMCID: PMC9647406 SCOPUS ID: 2-s2.0-85141519233 11/11/2022       3 Citations
  • Keratinocyte PIEZO1 modulates cutaneous mechanosensation. (Mikesell AR, Isaeva O, Moehring F, Sadler KE, Menzel AD, Stucky CL) Elife 2022 Sep 02;11 PMID: 36053009 PMCID: PMC9512397 SCOPUS ID: 2-s2.0-85139375441 09/03/2022       39 Citations
  • Astrocytic responses to high glucose impair barrier formation in cerebral microvessel endothelial cells. (Garvin J, Semenikhina M, Liu Q, Rarick K, Isaeva E, Levchenko V, Staruschenko A, Palygin O, Harder D, Cohen S) Am J Physiol Regul Integr Comp Physiol 2022 Jun 01;322(6):R571-R580 PMID: 35412389 PMCID: PMC9109795 SCOPUS ID: 2-s2.0-85130004068 04/13/2022       11 Citations
  • VU6036720: The First Potent and Selective In Vitro Inhibitor of Heteromeric Kir4.1/5.1 Inward Rectifier Potassium Channels. (McClenahan SJ, Kent CN, Kharade SV, Isaeva E, Williams JC, Han C, Terker A, Gresham R 3rd, Lazarenko RM, Days EL, Romaine IM, Bauer JA, Boutaud O, Sulikowski GA, Harris R, Weaver CD, Staruschenko A, Lindsley CW, Denton JS) Mol Pharmacol 2022 May;101(5):357-370 PMID: 35246480 PMCID: PMC9092466 SCOPUS ID: 2-s2.0-85128248706 03/06/2022       11 Citations
  • Adult resocialization restores sociability, reduced by adolescent social isolation in rats (Nikolaienko O, Isaeva EV) Fiziologichnyi Zhurnal 2022;68(2):9-13 SCOPUS ID: 2-s2.0-85131902257 01/01/2022       1 Citation
  • Crosstalk between epithelial sodium channels (ENaC) and basolateral potassium channels (Kir 4.1/Kir 5.1) in the cortical collecting duct. (Isaeva E, Bohovyk R, Fedoriuk M, Shalygin A, Klemens CA, Zietara A, Levchenko V, Denton JS, Staruschenko A, Palygin O) Br J Pharmacol 2022 Jun;179(12):2953-2968 PMID: 34904226 PMCID: PMC9106811 SCOPUS ID: 2-s2.0-85124542688 12/15/2021       11 Citations
  • Role of collecting duct principal cell NOS1β in sodium and potassium homeostasis. (Hyndman KA, Isaeva E, Palygin O, Mendoza LD, Rodan AR, Staruschenko A, Pollock JS) Physiol Rep 2021 Oct;9(20):e15080 PMID: 34665521 PMCID: PMC8525323 SCOPUS ID: 2-s2.0-85118118628 10/20/2021       2 Citations
  • Characterization of purinergic receptor 2 signaling in podocytes from diabetic kidneys. (Palygin O, Klemens CA, Isaeva E, Levchenko V, Spires DR, Dissanayake LV, Nikolaienko O, Ilatovskaya DV, Staruschenko A) iScience 2021 Jun 25;24(6):102528 PMID: 34142040 PMCID: PMC8188476 SCOPUS ID: 2-s2.0-85106559673 06/19/2021       14 Citations
  • Sexual dimorphism in the progression of type 2 diabetic kidney disease in T2DN rats. (Spires DR, Palygin O, Levchenko V, Isaeva E, Klemens CA, Khedr S, Nikolaienko O, Kriegel A, Cheng X, Yeo JY, Joe B, Staruschenko A) Physiol Genomics 2021 Jun 01;53(6):223-234 PMID: 33870721 PMCID: PMC8285576 SCOPUS ID: 2-s2.0-85108022875 04/20/2021       10 Citations
  • Scanning ion conductance microscopy of live human glomerulus. (Bohovyk R, Fedoriuk M, Isaeva E, Shevchuk A, Palygin O, Staruschenko A) J Cell Mol Med 2021 May;25(9):4216-4219 PMID: 33745233 PMCID: PMC8093965 SCOPUS ID: 2-s2.0-85102841283 03/22/2021       3 Citations
  • Kcnj16 knockout produces audiogenic seizures in the Dahl salt-sensitive rat. (Manis AD, Palygin O, Isaeva E, Levchenko V, LaViolette PS, Pavlov TS, Hodges MR, Staruschenko A) JCI Insight 2021 Jan 11;6(1) PMID: 33232300 PMCID: PMC7821607 SCOPUS ID: 2-s2.0-85099291307 11/25/2020       19 Citations
  • Behavioral, metabolic, and renal outcomes of 1-month isolation in adolescent male Dahl salt-sensitive rats. (Nikolaienko O, Isaeva E, Levchenko V, Palygin O, Staruschenko A) Am J Physiol Regul Integr Comp Physiol 2020 Dec 01;319(6):R684-R689 PMID: 33052061 PMCID: PMC7792816 SCOPUS ID: 2-s2.0-85098454395 10/15/2020       4 Citations
  • Role of opioid signaling in kidney damage during the development of salt-induced hypertension. (Golosova D, Palygin O, Bohovyk R, Klemens CA, Levchenko V, Spires DR, Isaeva E, El-Meanawy A, Staruschenko A) Life Sci Alliance 2020 Dec;3(12) PMID: 33046522 PMCID: PMC7556751 SCOPUS ID: 2-s2.0-85092887222 10/14/2020       21 Citations
  • NOX4-dependent regulation of ENaC in hypertension and diabetic kidney disease. (Pavlov TS, Palygin O, Isaeva E, Levchenko V, Khedr S, Blass G, Ilatovskaya DV, Cowley AW Jr, Staruschenko A) FASEB J 2020 Oct;34(10):13396-13408 PMID: 32799394 PMCID: PMC7722042 SCOPUS ID: 2-s2.0-85089380202 08/18/2020       29 Citations
  • Experimental models in the study of the mechanisms and consequences of epileptic seizures in neonatal period of life (Romanov A, Isaeva E) Fiziologichnyi Zhurnal 2020;66(2-3):93-100 SCOPUS ID: 2-s2.0-85107411208 01/01/2020    
  • Vibrodissociation method for isolation of defined nephron segments from human and rodent kidneys. (Isaeva E, Fedoriuk M, Bohovyk R, Klemens CA, Khedr S, Golosova D, Levchenko V, El-Meanawy A, Palygin O, Staruschenko A) Am J Physiol Renal Physiol 2019 Nov 01;317(5):F1398-F1403 PMID: 31588797 PMCID: PMC6879945 SCOPUS ID: 2-s2.0-85074674820 10/08/2019       10 Citations
  • Salt-deficient diet exacerbates cystogenesis in ARPKD via epithelial sodium channel (ENaC). (Ilatovskaya DV, Levchenko V, Pavlov TS, Isaeva E, Klemens CA, Johnson J, Liu P, Kriegel AJ, Staruschenko A) EBioMedicine 2019 Feb;40:663-674 PMID: 30745171 PMCID: PMC6413684 SCOPUS ID: 2-s2.0-85061112508 02/13/2019       25 Citations
  • BEHAVIORAL CONSEQUENCES OF ENTEROBIASIS IN RATS (Savotchenko AV, Semenikhina MO, Krasnianchuk IV, Bogovyk RI, Honcharova AE, Isaeva EV) Fiziologichnyi Zhurnal 2019;65(1):20-25 SCOPUS ID: 2-s2.0-85147149292 01/01/2019       2 Citations
  • PHARMACOLOGICAL BLOCKADE OF PROTEASE-ACTIVATED RECEPTORS 1 NORMALIZES BEHAVIORAL HYPEREXCITABILITY OF RATS IN THE LATENT STAGE OF THE EXPERIMENTAL MODEL OF TEMPORAL LOBE EPILEPSY (Semenikhina M, Bogovik R, Fedoryuk M, Lunko , Savotchenko A, Isaeva E) Fiziologichnyi Zhurnal 2019;65(3):7-11 SCOPUS ID: 2-s2.0-85107453962 01/01/2019       1 Citation
  • Inhibition of protease-activated receptor 1 ameliorates behavioral deficits and restores hippocampal synaptic plasticity in a rat model of status epilepticus. (Semenikhina M, Bogovyk R, Fedoriuk M, Nikolaienko O, Al Kury LT, Savotchenko A, Krishtal O, Isaeva E) Neurosci Lett 2019 Jan 23;692:64-68 PMID: 30391321 SCOPUS ID: 2-s2.0-85056000942 11/06/2018       14 Citations
  • Effects of protease-activated receptor 1 inhibition on anxiety and fear following status epilepticus. (Bogovyk R, Lunko O, Fedoriuk M, Isaev D, Krishtal O, Holmes GL, Isaeva E) Epilepsy Behav 2017 Feb;67:66-69 PMID: 28088683 SCOPUS ID: 2-s2.0-85009121782 01/16/2017       11 Citations
  • Acid-sensing ion channels regulate spontaneous inhibitory activity in the hippocampus: possible implications for epilepsy. (Ievglevskyi O, Isaev D, Netsyk O, Romanov A, Fedoriuk M, Maximyuk O, Isaeva E, Akaike N, Krishtal O) Philos Trans R Soc Lond B Biol Sci 2016 Aug 05;371(1700) PMID: 27377725 PMCID: PMC4938031 SCOPUS ID: 2-s2.0-84977577073 07/06/2016       29 Citations
  • Modulation of 4-aminopyridine-induced neuronal activity and local pO(2)in rat hippocampal slices by changing the flow rate of the superfusion medium. (Sydorenko VG, Komarov OS, Sushko BS, Romanov AK, Isaeva EV, Isaev DS) Fiziol Zh (1994) 2016;62(4):3-11 PMID: 29975468 SCOPUS ID: 2-s2.0-85051038034 01/01/2016    
  • Surface charge impact in nonsynaptic model of epilepsy in rat hippocampus. (Zapukhliak OS, Kachanovska VO, Isaeva EV, Netsyk OV, Isaev DS) Fiziol Zh (1994) 2016;62(2):35-40 PMID: 29537223 SCOPUS ID: 2-s2.0-85044617034 01/01/2016       2 Citations
  • Thrombin modulates persistent sodium current in CA1 pyramidal neurons of young and adult rat hippocampus. (Lunko OO, Isaev DS, Krishtal OO, Isaeva EV) Fiziol Zh (1994) 2015;61(4):5-10 PMID: 26552299 SCOPUS ID: 2-s2.0-84952719146 11/11/2015       1 Citation
  • Novel Potent Orthosteric Antagonist of ASIC1a Prevents NMDAR-Dependent LTP Induction. (Buta A, Maximyuk O, Kovalskyy D, Sukach V, Vovk M, Ievglevskyi O, Isaeva E, Isaev D, Savotchenko A, Krishtal O) J Med Chem 2015 Jun 11;58(11):4449-61 PMID: 25974655 SCOPUS ID: 2-s2.0-84935857385 05/15/2015       37 Citations
  • Hippocampal GABAergic interneurons coexpressing alpha7-nicotinic receptors and connexin-36 are able to improve neuronal viability under oxygen-glucose deprivation. (Voytenko LP, Lushnikova IV, Savotchenko AV, Isaeva EV, Skok MV, Lykhmus OY, Patseva MA, Skibo GG) Brain Res 2015 Aug 07;1616:134-45 PMID: 25966616 SCOPUS ID: 2-s2.0-84975110841 05/15/2015       20 Citations
  • Contribution of protease-activated receptor 1 in status epilepticus-induced epileptogenesis. (Isaev D, Lushnikova I, Lunko O, Zapukhliak O, Maximyuk O, Romanov A, Skibo GG, Tian C, Holmes GL, Isaeva E) Neurobiol Dis 2015 Jun;78:68-76 PMID: 25843668 PMCID: PMC4682556 SCOPUS ID: 2-s2.0-84926617762 04/07/2015       18 Citations
  • Neuraminidase inhibition primes short-term depression and suppresses long-term potentiation of synaptic transmission in the rat hippocampus. (Savotchenko A, Romanov A, Isaev D, Maximyuk O, Sydorenko V, Holmes GL, Isaeva E) Neural Plast 2015;2015:908190 PMID: 25802763 PMCID: PMC4329761 SCOPUS ID: 2-s2.0-84937134215 03/25/2015       9 Citations
  • Status epilepticus results in region-specific alterations in seizure susceptibility along the hippocampal longitudinal axis. (Isaeva E, Romanov A, Holmes GL, Isaev D) Epilepsy Res 2015 Feb;110:166-70 PMID: 25616469 PMCID: PMC4361808 SCOPUS ID: 2-s2.0-84921317713 01/27/2015       13 Citations
  • [EFFECT OF NEONATAL SEIZURES ON THE SYNAPTIC PLASTICITY OF RAT SOMATOSENSORY CORTEX]. (Isaeva EV, Lunko OO, Romano AK, Isaev DS) Fiziol Zh (1994) 2015;61(6):11-6 PMID: 27025040 SCOPUS ID: 2-s2.0-84988799233 01/01/2015    
  • Persistent sodium current properties in hippocampal CA1 pyramidal neurons of young and adult rats. (Lunko O, Isaev D, Maximyuk O, Ivanchick G, Sydorenko V, Krishtal O, Isaeva E) Neurosci Lett 2014 Jan 24;559:30-3 PMID: 24300033 SCOPUS ID: 2-s2.0-84890275510 12/05/2013       9 Citations
  • Focal epileptiform activity in the prefrontal cortex is associated with long-term attention and sociability deficits. (Hernan AE, Alexander A, Jenks KR, Barry J, Lenck-Santini PP, Isaeva E, Holmes GL, Scott RC) Neurobiol Dis 2014 Mar;63:25-34 PMID: 24269731 PMCID: PMC4397918 SCOPUS ID: 2-s2.0-84890289984 11/26/2013       65 Citations
  • Alteration of synaptic plasticity by neonatal seizures in rat somatosensory cortex. (Isaeva E, Isaev D, Holmes GL) Epilepsy Res 2013 Sep;106(1-2):280-3 PMID: 23623846 PMCID: PMC3758912 SCOPUS ID: 2-s2.0-84883296500 04/30/2013       31 Citations
  • Altered short-term plasticity in the prefrontal cortex after early life seizures. (Hernan AE, Holmes GL, Isaev D, Scott RC, Isaeva E) Neurobiol Dis 2013 Feb;50:120-6 PMID: 23064435 PMCID: PMC3534893 SCOPUS ID: 2-s2.0-84868488002 10/16/2012       40 Citations
  • Thrombin facilitates seizures through activation of persistent sodium current. (Isaeva E, Hernan A, Isaev D, Holmes GL) Ann Neurol 2012 Aug;72(2):192-8 PMID: 22926852 PMCID: PMC3430976 SCOPUS ID: 2-s2.0-84865595035 08/29/2012       33 Citations
  • Electrolyte therapy reduces spike-and-wave discharges in the WAG/Rij rat model of absence epilepsy. (Talnov AN, Isaeva E, Savotchenko AV, Dovgalets GV, Ochoa JG, Holmes GL, Isaev D) Epilepsy Behav 2012 Aug;24(4):399-402 PMID: 22749239 PMCID: PMC3408819 SCOPUS ID: 2-s2.0-84864296914 07/04/2012       1 Citation
  • Effect of neonatal epileptic attacks on the activity of neocortical neurons (Isaev DS, Isaeva EV, Savrasova AV, Holmes GL) Neurophysiology November 2011;43(3):227-228 SCOPUS ID: 2-s2.0-83555166011 11/01/2011    
  • Surface charge impact in low-magnesium model of seizure in rat hippocampus. (Isaev D, Ivanchick G, Khmyz V, Isaeva E, Savrasova A, Krishtal O, Holmes GL, Maximyuk O) J Neurophysiol 2012 Jan;107(1):417-23 PMID: 22031777 PMCID: PMC3349697 SCOPUS ID: 2-s2.0-84255182503 10/28/2011       46 Citations
  • Effect of neuraminidase treatment on persistent epileptiform activity in the rat hippocampus. (Isaeva E, Lushnikova I, Savrasova A, Skibo G, Holmes GL, Isaev D) Pharmacol Rep 2011;63(3):840-4 PMID: 21857096 SCOPUS ID: 2-s2.0-80051523283 08/23/2011       8 Citations
  • Anaesthetic and postanaesthetic effect of isoflurane on the multiple-unit activity of the immature rat hippocampus. (Isaeva EV, Isaev DS) Fiziol Zh (1994) 2011;57(1):17-20 PMID: 21513222 SCOPUS ID: 2-s2.0-79957717683 04/26/2011       1 Citation
  • Neuroaminidase reduces interictal spikes in a rat temporal lobe epilepsy model. (Isaev D, Zhao Q, Kleen JK, Lenck-Santini PP, Adstamongkonkul D, Isaeva E, Holmes GL) Epilepsia 2011 Mar;52(3):e12-5 PMID: 21366554 PMCID: PMC3265164 SCOPUS ID: 2-s2.0-79952541120 03/04/2011       9 Citations
  • Effect of neuraminidase treatment on persistent epileptiform activity in the rat hippocampus (Isaeva E, Lushnikova I, Savrasova A, Skibo G, Holmes GL, Isaev D) Pharmacological Reports 2011;63(3):840-844 SCOPUS ID: 2-s2.0-80051523283 01/01/2011       8 Citations
  • Blockade of endogenous neuraminidase leads to an increase of neuronal excitability and activity-dependent synaptogenesis in the rat hippocampus. (Isaeva E, Lushnikova I, Savrasova A, Skibo G, Holmes GL, Isaev D) Eur J Neurosci 2010 Dec;32(11):1889-96 PMID: 21044183 SCOPUS ID: 2-s2.0-78649708532 11/04/2010       18 Citations
  • The effect of neuraminidase blocker on gabazine-induced seizures in rat hippocampus. (Savrasova AV, Lushnikova IV, Isaeva EV, Skibo GG, Isaev DS, Kostyuk PG) Fiziol Zh (1994) 2010;56(4):14-8 PMID: 20964139 SCOPUS ID: 2-s2.0-79952066143 10/23/2010       7 Citations
  • Recurrent neonatal seizures result in long-term increases in neuronal network excitability in the rat neocortex. (Isaeva E, Isaev D, Savrasova A, Khazipov R, Holmes GL) Eur J Neurosci 2010 Apr;31(8):1446-55 PMID: 20384780 PMCID: PMC3148010 SCOPUS ID: 2-s2.0-77951155970 04/14/2010       50 Citations
  • Long-term suppression of GABAergic activity by neonatal seizures in rat somatosensory cortex. (Isaeva E, Isaev D, Khazipov R, Holmes GL) Epilepsy Res 2009 Dec;87(2-3):286-9 PMID: 19828295 PMCID: PMC2788005 SCOPUS ID: 2-s2.0-70449627028 10/16/2009       27 Citations
  • Mechanism of antiseizure effect of isoflurane in the immature rat hippocampus. (Isaeva EV) Fiziol Zh (1994) 2009;55(1):57-60 PMID: 19441716 SCOPUS ID: 2-s2.0-67650273288 05/16/2009       2 Citations
  • Effects of isoflurane on hippocampal seizures at immature rats in vivo. (Isaeva EV) Fiziol Zh (1994) 2008;54(5):40-5 PMID: 19058511 SCOPUS ID: 2-s2.0-58149335394 12/09/2008       4 Citations
  • Anesthetic and postanesthetic effects of isoflurane on neuronal activity in the rat hippocampus (Isaeva E, Isaev D, Holmes GL) Neurophysiology 2007;39(4-5):325-326 SCOPUS ID: 2-s2.0-73449100494 12/01/2007    
  • Role of extracellular sialic acid in regulation of neuronal and network excitability in the rat hippocampus. (Isaev D, Isaeva E, Shatskih T, Zhao Q, Smits NC, Shworak NW, Khazipov R, Holmes GL) J Neurosci 2007 Oct 24;27(43):11587-94 PMID: 17959801 PMCID: PMC6673228 SCOPUS ID: 2-s2.0-35548931238 10/26/2007       60 Citations
  • Shunting and hyperpolarizing GABAergic inhibition in the high-potassium model of ictogenesis in the developing rat hippocampus. (Isaev D, Isaeva E, Khazipov R, Holmes GL) Hippocampus 2007;17(3):210-9 PMID: 17294460 SCOPUS ID: 2-s2.0-33947205685 02/13/2007       19 Citations
  • Selective impairment of GABAergic synaptic transmission in the flurothyl model of neonatal seizures. (Isaeva E, Isaev D, Khazipov R, Holmes GL) Eur J Neurosci 2006 Mar;23(6):1559-66 PMID: 16553619 SCOPUS ID: 2-s2.0-33645100228 03/24/2006       53 Citations
  • Anticonvulsant action of GABA in the high potassium-low magnesium model of ictogenesis in the neonatal rat hippocampus in vivo and in vitro. (Isaev D, Isaeva E, Khazipov R, Holmes GL) J Neurophysiol 2005 Oct;94(4):2987-92 PMID: 16000527 SCOPUS ID: 2-s2.0-24944535227 07/08/2005       33 Citations
  • Mitochondrial redox state and Ca2+ sparks in permeabilized mammalian skeletal muscle. (Isaeva EV, Shkryl VM, Shirokova N) J Physiol 2005 Jun 15;565(Pt 3):855-72 PMID: 15845582 PMCID: PMC1464560 SCOPUS ID: 2-s2.0-21344464962 04/23/2005       74 Citations
  • Metabolic regulation of Ca2+ release in permeabilized mammalian skeletal muscle fibres. (Isaeva EV, Shirokova N) J Physiol 2003 Mar 01;547(Pt 2):453-62 PMID: 12562922 PMCID: PMC2342647 SCOPUS ID: 2-s2.0-0037337898 02/04/2003       49 Citations
  • Involvement of different types of Ca2+ currents in the control of the efficiency of inhibitory synaptic transmission between cultured hippocampal neurons (Fedulova SA, Isaeva EV, Veselovsky NS) Neurophysiology 2000;32(6):355-359 SCOPUS ID: 2-s2.0-0034436306 12/01/2000    
  • Possibility of multiquantal transmission at single inhibitory synapse in cultured rat hippocampal neurons. (Fedulova SA, Vasilyev DV, Isaeva EV, Romanyuk SG, Veselovsky NS) Neuroscience 1999;92(4):1217-30 PMID: 10426479 SCOPUS ID: 2-s2.0-0033048293 07/30/1999       40 Citations
  • Effect of nifedipine in high concentrations on inhibitory synaptic transmission (Isaeva EV) Neurophysiology January/February 1999;31(1):53-55 SCOPUS ID: 2-s2.0-27344454011 01/01/1999       1 Citation
  • Evoked inhibitory postsynaptic currents in the dynamics of development of cultured hippocampal neurons of rats (Isaeva EV, Sidorenko VG, Fedulova SA, Veselovskii NS) Neurophysiology September/October 1999;31(5):304-309 SCOPUS ID: 2-s2.0-0033360949 01/01/1999       2 Citations
  • Potassium channel blocker-induced presynaptic modulation of inhibitory synaptic transmission in hippocampal neurons of rats (Vasil'yev DV, Isaeva EV, Fedulova SA, Veselovskii NS) Neurophysiology July/October 1998;30(4-5):275-278 SCOPUS ID: 2-s2.0-33750127190 01/01/1998    
  • Voltage-dependent calcium channels in cultivated neurons of the rat hippocampus (Isaeva EV, Fedulova SA, Veselovskii NS) Neurophysiology July/October 1998;30(4-5):297-300 SCOPUS ID: 2-s2.0-33749502238 01/01/1998       4 Citations
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