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Anita D'Souza MD

Anita D'Souza MD

Assistant Professor

Institution: Medical College of Wisconsin
Department: Medicine
Division: Hematology and Oncology
Program: Hematology

Member of the Cancer Center


Research Experience

  • Clinical Trial
  • Epidemiology
  • Outcome Assessment (Health Care)
  • Quality of Life
  • Clinical Expertise

  • Amyloidosis
  • Bone Marrow Transplantation
  • Hematopoietic Stem Cell Transplantation
  • Leukemia, Plasma Cell
  • Multiple Myeloma
  • POEMS Syndrome
  • MCW Program / Core Facilities

  • CIBMTR
  • Publications

  • Hispanics have the lowest stem cell transplant utilization rate for autologous hematopoietic cell transplantation for multiple myeloma in the United States: A CIBMTR report. (Schriber JR, Hari PN, Ahn KW, Fei M, Costa LJ, Kharfan-Dabaja MA, Angel-Diaz M, Gale RP, Ganguly S, Girnius SK, Hashmi S, Pawarode A, Vesole DH, Wiernik PH, Wirk BM, Marks DI, Nishihori T, Olsson RF, Usmani SZ, Mark TM, Nieto YL, D'Souza A) Cancer 2017 May 04 PMID: 28472539 05/05/2017
  • Recipient Immune Modulation with Atorvastatin for Acute Graft-versus-Host Disease Prophylaxis after Allogeneic Transplantation. (Kanate AS, Hari PN, Pasquini MC, Visotcky A, Ahn KW, Boyd J, Guru Murthy GS, Rizzo JD, Saber W, Drobyski W, Michaelis L, Atallah E, Carlson KS, D'Souza A, Fenske TS, Cumpston A, Bunner P, Craig M, Horowitz MM, Hamadani M) Biol Blood Marrow Transplant 2017 Apr 12 PMID: 28412518 04/17/2017
  • Local Disease Control in Ocular Adnexal Lymphoproliferative Disorders: Comparative Outcomes of MALT Versus Non-MALT Histologies. (Dhakal B, Fenske TS, Ramalingam S, Shuff J, Epperla N, Hosking P, Rein L, Banerjee A, Hari P, D'Souza A, Shah N, Siker M, Griepentrog GJ, Harris GJ, Wells TS, Erickson BA, Hamadani M) Clin Lymphoma Myeloma Leuk 2017 May;17(5):305-311.e2 PMID: 28284742 03/13/2017
  • Response Assessment in Myeloma: Practical Manual on Consistent Reporting in an Era of Dramatic Therapeutic Advances. (Garderet L, D'Souza A, Jacobs P, van Biezen A, Schönland S, Kroeger N, Morris C, Hari P) Biol Blood Marrow Transplant 2017 Jul;23(7):1193-1202 PMID: 28285082 03/13/2017
  • Autologous Hematopoietic Cell Transplantation in Patients With Multiple Myeloma: Effect of Age. (Dhakal B, Nelson A, Guru Murthy GS, Fraser R, Eastwood D, Hamadani M, Pasquini M, D'Souza A, Hari P) Clin Lymphoma Myeloma Leuk 2017 Mar;17(3):165-172 PMID: 28159578 02/06/2017
  • Impact of pre-transplant depression on outcomes of allogeneic and autologous hematopoietic stem cell transplantation. (El-Jawahri A, Chen YB, Brazauskas R, He N, Lee SJ, Knight JM, Majhail N, Buchbinder D, Schears RM, Wirk BM, Wood WA, Ahmed I, Aljurf M, Szer J, Beattie SM, Battiwalla M, Dandoy C, Diaz MA, D'Souza A, Freytes CO, Gajewski J, Gergis U, Hashmi SK, Jakubowski A, Kamble RT, Kindwall-Keller T, Lazarus HM, Malone AK, Marks DI, Meehan K, Savani BN, Olsson RF, Rizzieri D, Steinberg A, Speckhart D, Szwajcer D, Schoemans H, Seo S, Ustun C, Atsuta Y, Dalal J, Sales-Bonfim C, Khera N, Hahn T, Saber W) Cancer 2017 May 15;123(10):1828-1838 PMID: 28102896 PMCID: PMC5419891 01/20/2017
  • Maintenance versus Induction Therapy Choice on Outcomes after Autologous Transplantation for Multiple Myeloma. (Cornell RF, D'Souza A, Kassim AA, Costa LJ, Innis-Shelton RD, Zhang MJ, Huang J, Abidi M, Aiello J, Akpek G, Bashey A, Bashir Q, Cerny J, Comenzo R, Diaz MA, Freytes C, Gale RP, Ganguly S, Hamadani M, Hashmi S, Holmberg L, Hossain N, Kamble RT, Kharfan-Dabaja M, Kindwall-Keller T, Kyle R, Kumar S, Lazarus H, Lee C, Maiolino A, Marks DI, Meehan K, Mikhael J, Nath R, Nishihori T, Olsson RF, Ramanathan M, Saad A, Seo S, Usmani S, Vesole D, Vij R, Vogl D, Wirk BM, Yared J, Krishnan A, Mark T, Nieto Y, Hari P) Biol Blood Marrow Transplant 2017 Feb;23(2):269-277 PMID: 27864161 PMCID: PMC5346183 11/20/2016
  • Allogeneic Transplantation for Relapsed Waldenström Macroglobulinemia and Lymphoplasmacytic Lymphoma. (Cornell RF, Bachanova V, D'Souza A, Woo-Ahn K, Martens M, Huang J, Al-Homsi AS, Chhabra S, Copelan E, Diaz MA, Freytes CO, Gale RP, Ganguly S, Hamadani M, Hildebrandt G, Kamble RT, Kharfan-Dabaja M, Kindwall-Keller T, Lazarus HM, Marks DI, Nishihori T, Olsson RF, Saad A, Usmani S, Vesole DH, Yared J, Mark T, Nieto Y, Hari P) Biol Blood Marrow Transplant 2017 Jan;23(1):60-66 PMID: 27789362 PMCID: PMC5182098 10/30/2016
  • Impact of haploidentical hematopoietic cell transplantation conditioning intensity on the incidence and severity of post-transplantation viral infections. (Raj RV, Hari P, Pasquini M, Epperla N, D'Souza A, Fenske T, Shaw BE, Rizzo JD, Drobyski W, Hamadani M) Bone Marrow Transplant 2016 Dec;51(12):1602-1604 PMID: 27595288 09/07/2016
  • Post-Transplant Outcomes in High-Risk Compared with Non-High-Risk Multiple Myeloma: A CIBMTR Analysis. (Scott EC, Hari P, Sharma M, Le-Rademacher J, Huang J, Vogl D, Abidi M, Beitinjaneh A, Fung H, Ganguly S, Hildebrandt G, Holmberg L, Kalaycio M, Kumar S, Kyle R, Lazarus H, Lee C, Maziarz RT, Meehan K, Mikhael J, Nishihori T, Ramanathan M, Usmani S, Tay J, Vesole D, Wirk B, Yared J, Savani BN, Gasparetto C, Krishnan A, Mark T, Nieto Y, D'Souza A) Biol Blood Marrow Transplant 2016 Oct;22(10):1893-9 PMID: 27496215 PMCID: PMC5090978 08/09/2016
  • Hematopoietic Progenitor Cell Mobilization with Ifosfamide, Carboplatin, and Etoposide Chemotherapy versus Plerixafor-Based Strategies in Patients with Hodgkin and Non-Hodgkin Lymphoma. (Dhakal B, Veltri LW, Fenske TS, Eastwood D, Craig MD, Cumpston A, Shillingburg A, Esselman J, Watkins K, Pasquini MC, D'Souza A, Hari P, Kanate AS, Hamadani M) Biol Blood Marrow Transplant 2016 Oct;22(10):1773-80 PMID: 27345140 06/28/2016
  • Heavy/light chain ratio normalization prior to transplant is of independent prognostic significance in multiple myeloma: a BMT CTN 0102 correlative study. (D'Souza A, Pasquini M, Logan B, Giralt S, Krishnan A, Antin J, Howard A, Goodman S, Qazilbash M, Knust K, Sahebi F, Weisdorf D, Vesole D, Stadtmauer E, Maloney D, Hari P) Br J Haematol 2016 Jun 13 PMID: 27292583 PMCID: PMC5154782 06/14/2016
  • Reduced-Intensity Transplantation for Lymphomas Using Haploidentical Related Donors Versus HLA-Matched Sibling Donors: A Center for International Blood and Marrow Transplant Research Analysis. (Ghosh N, Karmali R, Rocha V, Ahn KW, DiGilio A, Hari PN, Bachanova V, Bacher U, Dahi P, de Lima M, D'Souza A, Fenske TS, Ganguly S, Kharfan-Dabaja MA, Prestidge TD, Savani BN, Smith SM, Sureda AM, Waller EK, Jaglowski S, Herrera AF, Armand P, Salit RB, Wagner-Johnston ND, Fuchs E, Bolaños-Meade J, Hamadani M) J Clin Oncol 2016 Sep 10;34(26):3141-9 PMID: 27269951 PMCID: PMC5012706 06/09/2016
  • Allogeneic Hematopoietic Cell Transplantation in Multiple Myeloma: Impact of Disease Risk and Post Allograft Minimal Residual Disease on Survival. (Dhakal B, D'Souza A, Martens M, Kapke J, Harrington AM, Pasquini M, Saber W, Drobyski WR, Zhang MJ, Hamadani M, Hari PN) Clin Lymphoma Myeloma Leuk 2016 Jul;16(7):379-86 PMID: 27160644 05/11/2016
  • Allogeneic transplantation provides durable remission in a subset of DLBCL patients relapsing after autologous transplantation. (Fenske TS, Ahn KW, Graff TM, DiGilio A, Bashir Q, Kamble RT, Ayala E, Bacher U, Brammer JE, Cairo M, Chen A, Chen YB, Chhabra S, D'Souza A, Farooq U, Freytes C, Ganguly S, Hertzberg M, Inwards D, Jaglowski S, Kharfan-Dabaja MA, Lazarus HM, Nathan S, Pawarode A, Perales MA, Reddy N, Seo S, Sureda A, Smith SM, Hamadani M) Br J Haematol 2016 Jul;174(2):235-48 PMID: 26989808 PMCID: PMC4940282 03/19/2016
  • DAS181 Treatment of Severe Parainfluenza Virus 3 Pneumonia in Allogeneic Hematopoietic Stem Cell Transplant Recipients Requiring Mechanical Ventilation. (Dhakal B, D'Souza A, Pasquini M, Saber W, Fenske TS, Moss RB, Drobyski WR, Hari P, Abidi MZ) Case Rep Med 2016;2016:8503275 PMID: 26941799 PMCID: PMC4749780 03/05/2016
  • Signaling Pathways and Emerging Therapies in Multiple Myeloma. (Ramakrishnan V, D'Souza A) Curr Hematol Malig Rep 2016 Apr;11(2):156-64 PMID: 26922744 02/29/2016
  • New Light Chain Amyloid Response Criteria Help Risk Stratification of Patients by Day 100 after Autologous Hematopoietic Cell Transplantation. (D'Souza A, Huang J, Hari P) Biol Blood Marrow Transplant 2016 Apr;22(4):768-70 PMID: 26743343 PMCID: PMC4801777 01/09/2016
  • Significant Improvements in the Practice Patterns of Adult Related Donor Care in US Transplantation Centers. (Anthias C, Shaw BE, Kiefer DM, Liesveld JL, Yared J, Kamble RT, D'Souza A, Hematti P, Seftel MD, Norkin M, DeFilipp Z, Kasow KA, Abidi MH, Savani BN, Shah NN, Anderlini P, Diaz MA, Malone AK, Halter JP, Lazarus HM, Logan BR, Switzer GE, Pulsipher MA, Confer DL, O'Donnell PV) Biol Blood Marrow Transplant 2016 Mar;22(3):520-7 PMID: 26597080 PMCID: PMC4760616 11/26/2015
  • Monocyte recovery at day 100 is associated with improved survival in multiple myeloma patients who undergo allogeneic hematopoietic cell transplantation. (Dhakal B, Brazauskas R, Lara CA, Hari P, Pasquini M, D'Souza A) Bone Marrow Transplant 2016 Feb;51(2):297-9 PMID: 26457907 PMCID: PMC4956087 10/13/2015
  • Improved Outcomes After Autologous Hematopoietic Cell Transplantation for Light Chain Amyloidosis: A Center for International Blood and Marrow Transplant Research Study. (D'Souza A, Dispenzieri A, Wirk B, Zhang MJ, Huang J, Gertz MA, Kyle RA, Kumar S, Comenzo RL, Peter Gale R, Lazarus HM, Savani BN, Cornell RF, Weiss BM, Vogl DT, Freytes CO, Scott EC, Landau HJ, Moreb JS, Costa LJ, Ramanathan M, Callander NS, Kamble RT, Olsson RF, Ganguly S, Nishihori T, Kindwall-Keller TL, Wood WA, Mark TM, Hari P) J Clin Oncol 2015 Nov 10;33(32):3741-9 PMID: 26371138 PMCID: PMC4737858 09/16/2015
  • Contribution of chemotherapy mobilization to disease control in multiple myeloma treated with autologous hematopoietic cell transplantation. (Uy GL, Costa LJ, Hari PN, Zhang MJ, Huang JX, Anderson KC, Bredeson CN, Callander NS, Cornell RF, Perez MA, Dispenzieri A, Freytes CO, Gale RP, Garfall A, Gertz MA, Gibson J, Hamadani M, Lazarus HM, Kalaycio ME, Kamble RT, Kharfan-Dabaja MA, Krishnan AY, Kumar SK, Kyle RA, Landau HJ, Lee CH, Maiolino A, Marks DI, Mark TM, Munker R, Nishihori T, Olsson RF, Ramanathan M, Rodriguez TE, Saad AA, Savani BN, Schiller GJ, Schouten HC, Schriber JR, Scott E, Seo S, Sharma M, Ganguly S, Stadtmauer EA, Tay J, To LB, Vesole DH, Vogl DT, Wagner JL, Wirk B, Wood WA, D'Souza A) Bone Marrow Transplant 2015 Dec;50(12):1513-8 PMID: 26301967 PMCID: PMC4548821 08/25/2015
  • Changes in cardiac biomarkers with bortezomib treatment in patients with advanced cardiac amyloidosis. (Hussain AS, Hari P, Brazauskas R, Arce-Lara C, Pasquini M, Hamadani M, D'Souza A) Am J Hematol 2015 Nov;90(11):E212-3 PMID: 26284951 PMCID: PMC4618044 08/19/2015
  • Reduced-Intensity Allografting as First Transplantation Approach in Relapsed/Refractory Grades One and Two Follicular Lymphoma Provides Improved Outcomes in Long-Term Survivors. (Klyuchnikov E, Bacher U, Kröger NM, Hari PN, Ahn KW, Carreras J, Bachanova V, Bashey A, Cohen JB, D'Souza A, Freytes CO, Gale RP, Ganguly S, Hertzberg MS, Holmberg LA, Kharfan-Dabaja MA, Klein A, Ku GH, Laport GG, Lazarus HM, Miller AM, Mussetti A, Olsson RF, Slavin S, Usmani SZ, Vij R, Wood WA, Maloney DG, Sureda AM, Smith SM, Hamadani M) Biol Blood Marrow Transplant 2015 Dec;21(12):2091-9 PMID: 26253007 PMCID: PMC4639453 08/09/2015
  • Rehabilitation referrals and outcomes in the early period after hematopoietic cell transplantation. (Laine J, D'Souza A, Siddiqui S, Sayko O, Brazauskas R, Eickmeyer SM) Bone Marrow Transplant 2015 Oct;50(10):1352-7 PMID: 26146804 PMCID: PMC4598272 07/07/2015
  • CYP2C19*17 genetic polymorphism--an uncommon cause of voriconazole treatment failure. (Abidi MZ, D'Souza A, Kuppalli K, Ledeboer N, Hari P) Diagn Microbiol Infect Dis 2015 Sep;83(1):46-8 PMID: 25986028 05/20/2015
  • Impact of Pretransplantation (18)F-fluorodeoxy Glucose-Positron Emission Tomography Status on Outcomes after Allogeneic Hematopoietic Cell Transplantation for Non-Hodgkin Lymphoma. (Bachanova V, Burns LJ, Ahn KW, Laport GG, Akpek G, Kharfan-Dabaja MA, Nishihori T, Agura E, Armand P, Jaglowski SM, Cairo MS, Cashen AF, Cohen JB, D'Souza A, Freytes CO, Gale RP, Ganguly S, Ghosh N, Holmberg LA, Inwards DJ, Kanate AS, Lazarus HM, Malone AK, Munker R, Mussetti A, Norkin M, Prestidge TD, Rowe JM, Satwani P, Siddiqi T, Stiff PJ, William BM, Wirk B, Maloney DG, Smith SM, Sureda AM, Carreras J, Hamadani M, Center for International Blood and Marrow Transplant Research Lymphoma Working Committee) Biol Blood Marrow Transplant 2015 Sep;21(9):1605-11 PMID: 25983043 PMCID: PMC4558181 05/20/2015
  • Localized lymph node light chain amyloidosis. (Dhakal B, Harrington AM, Stadler ME, D'Souza A) Case Rep Hematol 2015;2015:816565 PMID: 25922771 PMCID: PMC4398934 04/30/2015
  • Polyneuropathy improvement following autologous stem cell transplantation for POEMS syndrome. (Karam C, Klein CJ, Dispenzieri A, Dyck PJ, Mandrekar J, D'Souza A, Mauermann ML) Neurology 2015 May 12;84(19):1981-7 PMID: 25878176 PMCID: PMC4433461 04/17/2015
  • Superior efficacy but higher cost of plerixafor and abbreviated-course G-CSF for mobilizing hematopoietic progenitor cells (HPC) in AL amyloidosis. (Dhakal B, D'Souza A, Arce-Lara C, Pasquini M, Saber W, Falvo F, Esselman J, Zellner K, Fenske T, Hari PN, Hamadani M) Bone Marrow Transplant 2015 Apr;50(4):610-2 PMID: 25621807 01/27/2015
  • Chronic GVHD and concurrent new-onset nephrotic syndrome in allogeneic transplant recipients. Incidence, pattern and therapeutic outcomes. (Dhakal B, Singavi A, Cohen EP, Dangal M, Palmer J, Dall A, D'Souza A, Hamadani M, Hari PN) Bone Marrow Transplant 2015 Mar;50(3):449-51 PMID: 25387097 11/12/2014
  • Is 'informed consent' an 'understood consent' in hematopoietic cell transplantation? (D'Souza A, Pasquini M, Spellecy R) Bone Marrow Transplant 2015 Jan;50(1):10-4 PMID: 25243618 PMCID: PMC4320584 09/23/2014
  • Plerixafor and abbreviated-course granulocyte colony-stimulating factor for mobilizing hematopoietic progenitor cells in light chain amyloidosis. (Dhakal B, Strouse C, D'Souza A, Arce-Lara C, Esselman J, Eastwood D, Pasquini M, Saber W, Drobyski W, Rizzo JD, Hari PN, Hamadani M) Biol Blood Marrow Transplant 2014 Dec;20(12):1926-31 PMID: 25111581 08/12/2014
  • Pharmaceutical amyloidosis associated with subcutaneous insulin and enfuvirtide administration. (D'Souza A, Theis JD, Vrana JA, Dogan A) Amyloid 2014 Jun;21(2):71-5 PMID: 24446896 PMCID: PMC4021035 01/23/2014
  • Low levels of interleukin-1 receptor antagonist (IL-1RA) predict engraftment syndrome after autologous stem cell transplantation in POEMS syndrome and other plasma cell neoplasms. (Keyzner A, D'Souza A, Lacy M, Gertz M, Hayman S, Buadi F, Kumar S, Dingli D, Engebretson A, Tong C, Dispenzieri A) Biol Blood Marrow Transplant 2013 Sep;19(9):1395-8 PMID: 23792270 06/25/2013
  • Localized tongue amyloidosis: a single institutional case series. (O'Reilly A, D'Souza A, Lust J, Price D) Otolaryngol Head Neck Surg 2013 Aug;149(2):240-4 PMID: 23715681 05/30/2013
  • Waldenström macroglobulinaemia: the key questions. (D'Souza A, Ansell S, Reeder C, Gertz MA) Br J Haematol 2013 Aug;162(3):295-303 PMID: 23651417 05/09/2013
  • Exploring the amyloid proteome in immunoglobulin-derived lymph node amyloidosis using laser microdissection/tandem mass spectrometry. (D'Souza A, Theis J, Quint P, Kyle R, Gertz M, Zeldenrust S, Vrana J, Dogan A, Dispenzieri A) Am J Hematol 2013 Jul;88(7):577-80 PMID: 23606017 04/23/2013
  • Association between ipilimumab and celiac disease. (Gentile NM, D'Souza A, Fujii LL, Wu TT, Murray JA) Mayo Clin Proc 2013 Apr;88(4):414-7 PMID: 23541015 04/02/2013
  • Localized Amyloidosis of the Urinary Bladder: New Pathological Features Revealed by Mass Spectrometry-Based Proteomics. (Mereuta O, D’Souza A, Vrana J, Theis J, Quint P, Dispenzieri A, Grogg K, Dogan A. ) Modern Pathology Mod Pathol. 2013;26:234A 02/01/2013
  • Localized insulin-derived amyloidosis: a potential pitfall in the diagnosis of systemic amyloidosis by fat aspirate. (D'Souza A, Theis JD, Vrana JA, Buadi F, Dispenzieri A, Dogan A) Am J Hematol 2012 Nov;87(11):E131-2 PMID: 23044893 10/10/2012
  • Lymphoma-associated versus lymphocytic-variant hypereosinophilia. (D'Souza A, Pardanani A, Tefferi A) Leuk Lymphoma 2012 Nov;53(11):2103-4 PMID: 22762549 07/06/2012
  • Long-term follow-up of FIP1L1-PDGFRA-mutated patients with eosinophilia: survival and clinical outcome. (Pardanani A, D'Souza A, Knudson RA, Hanson CA, Ketterling RP, Tefferi A) Leukemia 2012 Nov;26(11):2439-41 PMID: 22705991 06/19/2012
  • Long-term outcomes after autologous stem cell transplantation for patients with POEMS syndrome (osteosclerotic myeloma): a single-center experience. (D'Souza A, Lacy M, Gertz M, Kumar S, Buadi F, Hayman S, Dingli D, Zeldenrust S, Kyle R, Ansell S, Inwards D, Johnston P, Micallef I, Porrata L, Litzow M, Gastineau D, Hogan W, Dispenzieri A) Blood 2012 Jul 05;120(1):56-62 PMID: 22611150 05/23/2012
  • Clinically significant anti-A(1) in a presumed ABO-identical hematopoietic stem cell transplant recipient: a case report. (Jaben EA, Jacob EK, Tauscher C, D'Souza A, Hogan WJ, Stubbs JR) Transfusion 2013 Jan;53(1):202-5 PMID: 22574682 05/12/2012
  • The utility of plasma vascular endothelial growth factor levels in the diagnosis and follow-up of patients with POEMS syndrome. (D'Souza A, Hayman SR, Buadi F, Mauermann M, Lacy MQ, Gertz MA, Kyle RA, Kumar S, Greipp PR, Lust JA, Russell SJ, Zeldenrust S, Dingli D, Witzig TE, Rajkumar SV, Dispenzieri A) Blood 2011 Oct 27;118(17):4663-5 PMID: 21881050 09/02/2011
  • Progressive multifocal leukoencephalopathy in chronic lymphocytic leukemia: a report of three cases and review of the literature. (D'Souza A, Wilson J, Mukherjee S, Jaiyesimi I) Clin Lymphoma Myeloma Leuk 2010 Feb;10(1):E1-9 PMID: 20223720 03/13/2010
  • Granulocyte colony-stimulating factor administration: adverse events. (D'Souza A, Jaiyesimi I, Trainor L, Venuturumili P) Transfus Med Rev 2008 Oct;22(4):280-90 PMID: 18848155 10/14/2008
  • Last update: 05/19/2017
    jenkins-FCD Prod-106 bf6a561a509ceb2e2c031c53c40b81b12394cec4