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Ivor J. Benjamin MD

Ivor J. Benjamin MD profile photo picture

Center Director, Professor

Institution: Medical College of Wisconsin
Department: Medicine
Division: Cardiology
Program: Administration

Director of the Cardiovascular Center
Member of the Cancer Center
Member of the Center for Disease Prevention Research (CDPR)

View Curriculum Vitae

Publications (144)

  • Myocardial Strain for the Differentiation of Myocardial Involvement in the Post-Acute Sequelae of COVID-19-A Multiparametric Cardiac MRI Study. (Ibrahim EH, Rubenstein J, Sosa A, Stojanovska J, Pan A, North P, Rui H, Benjamin I) Tomography 2024 Feb 27;10(3):331-348 PMID: 38535768 PMCID: PMC10974260 SCOPUS ID: 2-s2.0-85188901578 03/27/2024    
  • The American Heart Association at 100: A Century of Scientific Progress and the Future of Cardiovascular Science: A Presidential Advisory From the American Heart Association. (Elkind MSV, Arnett DK, Benjamin IJ, Eckel RH, Grant AO, Houser SR, Jacobs AK, Jones DW, Robertson RM, Sacco RL, Smith SC Jr, Weisfeldt ML, Wu JC, Jessup M) Circulation 2024 Mar 19;149(12):e964-e985 PMID: 38344851 SCOPUS ID: 2-s2.0-85188281363 02/12/2024       1 Citation
  • Profibrotic COVID-19 subphenotype exhibits enhanced localized ER-dependent HSP47+ expression in cardiac myofibroblasts in situ. (Jacobs ER, Ross GR, Padilla N, Pan AY, Liegl M, Puzyrenko A, Lai S, Dai Q, Uche N, Rubenstein JC, North PE, Ibrahim EH, Sun Y, Felix JC, Rui H, Benjamin IJ) J Mol Cell Cardiol 2023 Dec;185:1-12 PMID: 37839656 PMCID: PMC11000691 SCOPUS ID: 2-s2.0-85174455933 10/16/2023    
  • Carvedilol Phenocopies PGC-1α Overexpression to Alleviate Oxidative Stress, Mitochondrial Dysfunction and Prevent Doxorubicin-Induced Toxicity in Human iPSC-Derived Cardiomyocytes. (Uche N, Dai Q, Lai S, Kolander K, Thao M, Schibly E, Sendaydiego X, Zielonka J, Benjamin IJ) Antioxidants (Basel) 2023 Aug 09;12(8) PMID: 37627583 PMCID: PMC10451268 SCOPUS ID: 2-s2.0-85169136890 08/26/2023    
  • Nuclear damage in LMNA mutant iPSC-derived cardiomyocytes is associated with impaired lamin localization to the nuclear envelope. (Wallace M, Zahr H, Perati S, Morsink CD, Johnson LE, Gacita AM, Lai S, Wallrath LL, Benjamin IJ, McNally EM, Kirby TJ, Lammerding J) Mol Biol Cell 2023 Aug 16;34(12):mbcE21100527 PMID: 37585285 PMCID: PMC10846625 SCOPUS ID: 2-s2.0-85183571175 08/16/2023    
  • Collagen-Specific HSP47+ Myofibroblasts and CD163+ Macrophages Identify Profibrotic Phenotypes in Deceased Hearts With SARS-CoV-2 Infections. (Puzyrenko A, Jacobs ER, Padilla N, Devine A, Aljadah M, Gantner BN, Pan AY, Lai S, Dai Q, Rubenstein JC, North PE, Simpson PM, Willoughby RE, O'Meara CC, Flinn MA, Lough JW, Ibrahim EH, Zheng Z, Sun Y, Felix J, Hunt BC, Ross G, Rui H, Benjamin IJ) J Am Heart Assoc 2023 Feb 21;12(4):e027990 PMID: 36789856 PMCID: PMC10111490 SCOPUS ID: 2-s2.0-85148479620 02/16/2023       2 Citations
  • Penicillin Reactions in Patients With Severe Rheumatic Heart Disease: A Presidential Advisory From the American Heart Association. (Sanyahumbi A, Ali S, Benjamin IJ, Karthikeyan G, Okello E, Sable CA, Taubert K, Wyber R, Zuhlke L, Carapetis JR, Beaton AZ, American Heart Association) J Am Heart Assoc 2022 Mar;11(5):e024517 PMID: 35049336 PMCID: PMC9075066 SCOPUS ID: 2-s2.0-85125554299 01/21/2022       7 Citations
  • Modulation of muscle redox and protein aggregation rescues lethality caused by mutant lamins. (Coombs GS, Rios-Monterrosa JL, Lai S, Dai Q, Goll AC, Ketterer MR, Valdes MF, Uche N, Benjamin IJ, Wallrath LL) Redox Biol 2021 Nov 25;48:102196 PMID: 34872044 PMCID: PMC8646998 SCOPUS ID: 2-s2.0-85120438753 12/07/2021       5 Citations
  • Modulation of muscle redox and protein aggregation rescues lethality caused by mutant lamins (Coombs GS, Rios-Monterrosa JL, Lai S, Dai Q, Goll AC, Ketterer MR, Valdes MF, Uche N, Benjamin IJ, Wallrath LL) Redox Biology December 2021;48 SCOPUS ID: 2-s2.0-85120438753 12/01/2021       4 Citations
  • The history and geographic distribution of a KCNQ1 atrial fibrillation risk allele. (Hateley S, Lopez-Izquierdo A, Jou CJ, Cho S, Schraiber JG, Song S, Maguire CT, Torres N, Riedel M, Bowles NE, Arrington CB, Kennedy BJ, Etheridge SP, Lai S, Pribble C, Meyers L, Lundahl D, Byrnes J, Granka JM, Kauffman CA, Lemmon G, Boyden S, Scott Watkins W, Karren MA, Knight S, Brent Muhlestein J, Carlquist JF, Anderson JL, Chahine KG, Shah KU, Ball CA, Benjamin IJ, Yandell M, Tristani-Firouzi M) Nat Commun 2021 Nov 08;12(1):6442 PMID: 34750360 PMCID: PMC8575962 SCOPUS ID: 2-s2.0-85118668606 11/10/2021       6 Citations
  • Impact of the COVID-19 Pandemic on Cardiovascular Science: Anticipating Problems and Potential Solutions: A Presidential Advisory From the American Heart Association. (McNally EM, Elkind MSV, Benjamin IJ, Chung MK, Dillon GH, Hernandez AF, Ibeh C, Lloyd-Jones DM, McCullough LD, Wold LE, Wright DR, Wu JC) Circulation 2021 Dec 07;144(23):e461-e471 PMID: 34719260 PMCID: PMC10227717 SCOPUS ID: 2-s2.0-85122546616 11/02/2021       11 Citations
  • Hypertriglyceridemia during hospitalization independently associates with mortality in patients with COVID-19. (Dai W, Lund H, Chen Y, Zhang J, Osinski K, Jones SZ, Kreuziger LB, López JA, Benjamin IJ, Silverstein RL, Zheng Z) J Clin Lipidol 2021;15(5):724-731 PMID: 34470719 PMCID: PMC8353976 SCOPUS ID: 2-s2.0-85114047849 09/03/2021       10 Citations
  • Opioid Use and Its Relationship to Cardiovascular Disease and Brain Health: A Presidential Advisory From the American Heart Association. (Chow SL, Sasson C, Benjamin IJ, Califf RM, Compton WM, Oliva EM, Robson C, Sanchez EJ) Circulation 2021 Sep 28;144(13):e218-e232 PMID: 34407637 SCOPUS ID: 2-s2.0-85116553125 08/20/2021       18 Citations
  • Pneumocytes are distinguished by highly elevated expression of the ER stress biomarker GRP78, a co-receptor for SARS-CoV-2, in COVID-19 autopsies. (Puzyrenko A, Jacobs ER, Sun Y, Felix JC, Sheinin Y, Ge L, Lai S, Dai Q, Gantner BN, Nanchal R, North PE, Simpson PM, Rui H, Benjamin IJ) Cell Stress Chaperones 2021 Sep;26(5):859-868 PMID: 34382151 PMCID: PMC8357488 SCOPUS ID: 2-s2.0-85112285201 08/13/2021       17 Citations
  • 2020 American Heart Association and American College of Cardiology Consensus Conference on Professionalism and Ethics: A Consensus Conference Report. (Executive Committee, Benjamin IJ, Valentine CM, Oetgen WJ, Sheehan KA, Task Force 1, Brindis RG, Roach WH Jr, Harrington RA, Levine GN, Redberg RF, Broccolo BM, Hernandez AF, Task Force 2, Douglas PS, Piña IL, Benjamin EJ, Coylewright MJ, Saucedo JF, Ferdinand KC, Hayes SN, Poppas A, Task Force 3, Furie KL, Mehta LS, Erwin JP 3rd, Mieres JH, Murphy DJ Jr, Weissman G, West CP, Task Force 4, Lawrence WE Jr, Masoudi FA, Jones CP, Matlock DD, Miller JE, Spertus JA, Todman L, Task Force 5, Biga C, Chazal RA, Creager MA, Fry ET, Mack MJ, Yancy CW, Anderson RE) J Am Coll Cardiol 2021 Jun 22;77(24):3079-3133 PMID: 33994057 PMCID: PMC8091280 SCOPUS ID: 2-s2.0-85111094986 05/18/2021       12 Citations
  • 2020 American Heart Association and American College of Cardiology Consensus Conference on Professionalism and Ethics: A Consensus Conference Report. (Benjamin IJ, Valentine CM, Oetgen WJ, Sheehan KA, Brindis RG, Roach WH Jr, Harrington RA, Levine GN, Redberg RF, Broccolo BM, Hernandez AF, Douglas PS, Piña IL, Benjamin EJ, Coylewright MJ, Saucedo JF, Ferdinand KC, Hayes SN, Poppas A, Furie KL, Mehta LS, Erwin JP 3rd, Mieres JH, Murphy DJ Jr, Weissman G, West CP, Lawrence WE Jr, Masoudi FA, Jones CP, Matlock DD, Miller JE, Spertus JA, Todman L, Biga C, Chazal RA, Creager MA, Fry ET, Mack MJ, Yancy CW, Anderson RE) Circulation 2021 Jun 22;143(25):e1035-e1087 PMID: 33974449 SCOPUS ID: 2-s2.0-85108556877 05/12/2021       13 Citations
  • An immigrant's experience: science is a discipline without borders. (Benjamin IJ) J Clin Invest 2021 May 03;131(9) PMID: 33938451 PMCID: PMC8087192 SCOPUS ID: 2-s2.0-85105277080 05/04/2021    
  • Identification and analysis of circulating long non-coding RNAs with high significance in diabetic cardiomyopathy. (Pant T, Dhanasekaran A, Zhao M, Thorp EB, Forbess JM, Bosnjak ZJ, Benjamin IJ, Ge ZD) Sci Rep 2021 Jan 28;11(1):2571 PMID: 33510471 PMCID: PMC7843621 SCOPUS ID: 2-s2.0-85100002752 01/30/2021       12 Citations
  • Optimizing observer performance of clinic blood Pressure measurement: A position statement from the Lancet Commission on Hypertension Group (Padwal R, Campbell NRC, Schutte AE, Olsen MH, Delles C, Etyang A, Kennedy Cruickshank J, Stergiou G, Rakotz MK, Wozniak G, Jaffe MG, Benjamin I, Parati G, Sharman JE) Revista Panamericana de Salud Publica/Pan American Journal of Public Health July 2020;44 SCOPUS ID: 2-s2.0-85093100765 07/01/2020    
  • Protecting Medical Trainees on the COVID-19 Frontlines Saves Us All. (Harrington RA, Elkind MSV, Benjamin IJ) Circulation 2020 May 05;141(18):e775-e777 PMID: 32250654 PMCID: PMC7176273 SCOPUS ID: 2-s2.0-85085881212 04/07/2020       28 Citations
  • The Role of the American Heart Association in the Global COVID-19 Pandemic. (Elkind MSV, Harrington RA, Benjamin IJ) Circulation 2020 Apr 14;141(15):e743-e745 PMID: 32181680 PMCID: PMC7172571 SCOPUS ID: 2-s2.0-85083175330 03/18/2020       31 Citations
  • Advancing Healthcare Reform: The American Heart Association's 2020 Statement of Principles for Adequate, Accessible, and Affordable Health Care: A Presidential Advisory From the American Heart Association. (Warner JJ, Benjamin IJ, Churchwell K, Firestone G, Gardner TJ, Johnson JC, Ng-Osorio J, Rodriguez CJ, Todman L, Yaffe K, Yancy CW, Harrington RA, American Heart Association Advocacy Coordinating Committee) Circulation 2020 Mar 10;141(10):e601-e614 PMID: 32008369 SCOPUS ID: 2-s2.0-85081944143 02/06/2020       20 Citations
  • Lancet commission on hypertension group position statement on the global improvement of accuracy standards for devices that measure blood pressure (Sharman JE, O'Brien E, Alpert B, Schutte AE, Delles C, Olsen MH, Asmar R, Atkins N, Barbosa E, Calhoun D, Campbell NRC, Chalmers J, Benjamin I, Jennings G, Laurent S, Boutouyrie P, Lopez-Jaramillo P, McManus RJ, Mihailidou AS, Ordunez P, Padwal R, Palatini P, Parati G, Poulter N, Rakotz MK, Rosendorff C, Saladini F, Scuteri A, Barroso WS, Cho MC, Sung KC, Townsend RR, Wang JG, Hansen TW, Wozniak G, Stergiou G) Revista Panamericana de Salud Publica/Pan American Journal of Public Health 2020;44 SCOPUS ID: 2-s2.0-85088924128 01/01/2020    
  • Lancet Commission on Hypertension group position statement on the global improvement of accuracy standards for devices that measure blood pressure. (Sharman JE, O'Brien E, Alpert B, Schutte AE, Delles C, Hecht Olsen M, Asmar R, Atkins N, Barbosa E, Calhoun D, Campbell NRC, Chalmers J, Benjamin I, Jennings G, Laurent S, Boutouyrie P, Lopez-Jaramillo P, McManus RJ, Mihailidou AS, Ordunez P, Padwal R, Palatini P, Parati G, Poulter N, Rakotz MK, Rosendorff C, Saladini F, Scuteri A, Sebba Barroso W, Cho MC, Sung KC, Townsend RR, Wang JG, Willum Hansen T, Wozniak G, Stergiou G, Lancet Commission on Hypertension Group) J Hypertens 2020 Jan;38(1):21-29 PMID: 31790375 PMCID: PMC6919228 SCOPUS ID: 2-s2.0-85072243957 12/04/2019       93 Citations
  • Investigation of a dilated cardiomyopathy-associated variant in BAG3 using genome-edited iPSC-derived cardiomyocytes. (McDermott-Roe C, Lv W, Maximova T, Wada S, Bukowy J, Marquez M, Lai S, Shehu A, Benjamin I, Geurts A, Musunuru K) JCI Insight 2019 Nov 14;4(22) PMID: 31723063 PMCID: PMC6948852 SCOPUS ID: 2-s2.0-85077370393 11/15/2019       30 Citations
  • Fixed-dose combination antihypertensive medications. (Benjamin IJ, Kreutz R, Olsen MH, Schutte AE, Lopez-Jaramillo P, Frieden TR, Sliwa K, Lackland DT, Brainin M) Lancet 2019 Aug 24;394(10199):637-638 PMID: 31320200 SCOPUS ID: 2-s2.0-85070558525 07/20/2019       39 Citations
  • Fixed-dose combination antihypertensive medications (Ivor J. Benjamin, Reinhold Kreutz, Michael H. Olsen, Aletta E. Schutte, Patricio Lopez-Jaramillo; *Thomas R. Freiden, Karen Sliwa, Daniel T. Lackland, Michael Brainin) The Lancet Global Health 07/15/2019    
  • 2019 ACC/AHA/ASE Advanced Training statement on echocardiography (Revision of the 2003 ACC/AHA Clinical Competence Statement on Echocardiography): a report of the ACC competency management committee (Wiegers SE, Ryan T, Arrighi JA, Brown SM, Canaday B, Damp JB, Diaz-Gomez JL, Figueredo VM, Garcia MJ, Gillam LD, Griffin BP, Kirkpatrick JN, Klarich KW, Lui GK, Maffett S, Naqvi TZ, Patel AR, Poulin MF, Rose GA, Swaminathan M, Mendes LA, Adams JE, Brush JE, Dec GW, Denktas A, Fernandes S, Freeman R, Hahn RT, Halperin JL, Housholder-Hughes SD, Khan SS, Lin CH, Marine JE, McPherson JA, Niazi K, Ryan T, Solomon MA, Spicer RL, Tam M, Wang A, Weissman G, Weitz HH, Williams ES, Valentine CM, Attebery TW, Oetgen WJ, Phoubandith DR, Callahan TV, Scholtz A, Benjamin I, Brown N, Robertson RM, Lindner J, Wiegerink R, LaFluria C) Circulation: Cardiovascular Imaging 1 July 2019;12(7) SCOPUS ID: 2-s2.0-85073589978 07/01/2019       7 Citations
  • Optimizing observer performance of clinic blood pressure measurement: a position statement from the Lancet Commission on Hypertension Group. (Padwal R, Campbell NRC, Schutte AE, Olsen MH, Delles C, Etyang A, Cruickshank JK, Stergiou G, Rakotz MK, Wozniak G, Jaffe MG, Benjamin I, Parati G, Sharman JE) J Hypertens 2019 Sep;37(9):1737-1745 PMID: 31034450 PMCID: PMC6686964 SCOPUS ID: 2-s2.0-85070850449 04/30/2019       75 Citations
  • Global Improvement of Accuracy Standards for Devices that Measure Blood Pressure (Corresponding Author: James Sharman Co-Authors: Eoin O’Brien; Bruce Alpert; Aletta Schutte; Christian Delles; Michael Hecht-Olsen; Roland Asmar; Neil Atkins; Eduardo Barbosa; David Calhoun; Norm Campbell; John Chalmers; Ivor Benjamin; Garry Jennings; Stephane Laurent; Pierre Boutouyrie; Patricio Lopez-Jaramillo; Richard McManus; Anastasia Mihailidou; Pedro Ordunez; Raj Padwal; Paolo Palatini; Gianfranco Parati; Neil Poulter; Michael Rakotz; Clive Rosendorff; Francesca Saladini; Angelo Scuteri; Weimar Sebba Barroso; Myeong-Chan Cho; Ki-Chul Sung; Raymond Townsend; Ji-Guang Wang; Tine Willum Hansen; Gregory Wozniak; George Stergiou ) The Lancet Global Health 04/24/2019    
  • Wearable devices transform cardiac care and treatment (Oujiri, James, MD; Benjamin, Ivor, MD) Milwaukee Journal Sentinel 02/27/2019    
  • Transcription Factor EB Activation Rescues Advanced αB-Crystallin Mutation-Induced Cardiomyopathy by Normalizing Desmin Localization. (Ma X, Mani K, Liu H, Kovacs A, Murphy JT, Foroughi L, French BA, Weinheimer CJ, Kraja A, Benjamin IJ, Hill JA, Javaheri A, Diwan A) J Am Heart Assoc 2019 Feb 19;8(4):e010866 PMID: 30773991 PMCID: PMC6405666 SCOPUS ID: 2-s2.0-85061707716 02/19/2019       38 Citations
  • Cooperative interaction among BMAL1, HSF1, and p53 protects mammalian cells from UV stress. (Kawamura G, Hattori M, Takamatsu K, Tsukada T, Ninomiya Y, Benjamin I, Sassone-Corsi P, Ozawa T, Tamaru T) Commun Biol 2018;1:204 PMID: 30480104 PMCID: PMC6250677 SCOPUS ID: 2-s2.0-85066236743 11/28/2018       22 Citations
  • Correction for Gabai et al., "Heat Shock Transcription Factor Hsf1 Is Involved in Tumor Progression via Regulation of Hypoxia-Inducible Factor 1 and RNA-Binding Protein HuR". (Gabai VL, Meng L, Kim G, Mills TA, Benjamin IJ, Sherman MY) Mol Cell Biol 2017 Oct 15;37(20) PMID: 28951485 PMCID: PMC5615190 SCOPUS ID: 2-s2.0-85030103199 09/28/2017    
  • Why publish in the American Journal of Physiology-Heart and Circulatory Physiology? (Zucker IH, Lindsey ML, Delmar M, De Windt LJ, Des Rosiers C, Diz DI, Hester RL, Jones SP, Kanagy NL, Kitakaze M, Liao R, Lopaschuk GD, Patel KP, Recchia FA, Sadoshima J, Shah AM, Ungvari Z, Benjamin IJ, Blaustein MP, Charkoudian N, Efimov IR, Gutterman D, Kass DA, Liao Y, O'Leary DS, Ripplinger CM, Wolin MS) Am J Physiol Heart Circ Physiol 2017 Aug 01;313(2):H221-H223 PMID: 28626081 SCOPUS ID: 2-s2.0-85026768548 06/20/2017       3 Citations
  • Genomic Approaches to Hypertension. (Dodoo SN, Benjamin IJ) Cardiol Clin 2017 May;35(2):185-196 PMID: 28411893 SCOPUS ID: 2-s2.0-85017435059 04/17/2017       9 Citations
  • The growing world of small heat shock proteins: from structure to functions. (Carra S, Alberti S, Arrigo PA, Benesch JL, Benjamin IJ, Boelens W, Bartelt-Kirbach B, Brundel BJJM, Buchner J, Bukau B, Carver JA, Ecroyd H, Emanuelsson C, Finet S, Golenhofen N, Goloubinoff P, Gusev N, Haslbeck M, Hightower LE, Kampinga HH, Klevit RE, Liberek K, Mchaourab HS, McMenimen KA, Poletti A, Quinlan R, Strelkov SV, Toth ME, Vierling E, Tanguay RM) Cell Stress Chaperones 2017 Jul;22(4):601-611 PMID: 28364346 PMCID: PMC5465036 SCOPUS ID: 2-s2.0-85016635209 04/02/2017       125 Citations
  • The growing world of small heat shock proteins: from structure to functions (Serena Carra, Simon Alberti, Patrick A. Arrigo, Justin L. Benesch, Ivor J. Benjamin, Wilbert Boelens, Britta Bartelt-Kirbach, Bianca J. J. M. Brundel, Johannes Buchner, Bernd Bukau, John A. Carver, Heath Ecroyd, Cecilia Emanuelsson, Stephanie Finet, Nikola Golenhofen, Pierre Goloubinoff, Nikolai Gusev, Martin Haslbeck, Lawrence E. Hightower, Harm H. Kampinga, Rachel E. Klevit, Krzysztof Liberek, Hassane S. Mchaourab, Kathryn A. McMenimen, Angelo Poletti, Roy Quinlan, Sergei V. Strelkov, Melinda E. Toth, Elizabeth Vierling, Robert M. Tanguay) Cell Stress Chaperones. 2017 Jul; 22(4): 601–611 03/31/2017    
  • Efficient Precision Genome Editing in iPSCs via Genetic Co-targeting with Selection. (Mitzelfelt KA, McDermott-Roe C, Grzybowski MN, Marquez M, Kuo CT, Riedel M, Lai S, Choi MJ, Kolander KD, Helbling D, Dimmock DP, Battle MA, Jou CJ, Tristani-Firouzi M, Verbsky JW, Benjamin IJ, Geurts AM) Stem Cell Reports 2017 Mar 14;8(3):491-499 PMID: 28238794 PMCID: PMC5355643 SCOPUS ID: 2-s2.0-85013648619 02/28/2017       24 Citations
  • Perspectives from NHLBI Global Health Think Tank Meeting for Late Stage (T4) Translation Research. (Engelgau MM, Peprah E, Sampson UKA, Mishoe H, Benjamin IJ, Douglas PS, Hochman JS, Ridker PM, Brandes N, Checkley W, El-Saharty S, Ezzati M, Hennis A, Jiang L, Krumholz HM, Lamourelle G, Makani J, Narayan KMV, Ohene-Frempong K, Straus SE, Stuckler D, Chambers DA, Belis D, Bennett GC, Boyington JE, Creazzo TL, de Jesus JM, Krishnamurti C, Lowden MR, Punturieri A, Shero ST, Young NS, Zou S, Mensah GA) Glob Heart 2017 Dec;12(4):341-348 PMID: 27452772 SCOPUS ID: 2-s2.0-85002910620 07/28/2016       10 Citations
  • Heat Shock Factor 1 Is a Substrate for p38 Mitogen-Activated Protein Kinases. (Dayalan Naidu S, Sutherland C, Zhang Y, Risco A, de la Vega L, Caunt CJ, Hastie CJ, Lamont DJ, Torrente L, Chowdhry S, Benjamin IJ, Keyse SM, Cuenda A, Dinkova-Kostova AT) Mol Cell Biol 2016 Sep 15;36(18):2403-17 PMID: 27354066 PMCID: PMC5007788 SCOPUS ID: 2-s2.0-84988336071 06/30/2016       53 Citations
  • The Human 343delT HSPB5 Chaperone Associated with Early-onset Skeletal Myopathy Causes Defects in Protein Solubility. (Mitzelfelt KA, Limphong P, Choi MJ, Kondrat FD, Lai S, Kolander KD, Kwok WM, Dai Q, Grzybowski MN, Zhang H, Taylor GM, Lui Q, Thao MT, Hudson JA, Barresi R, Bushby K, Jungbluth H, Wraige E, Geurts AM, Benesch JL, Riedel M, Christians ES, Minella AC, Benjamin IJ) J Biol Chem 2016 Jul 15;291(29):14939-53 PMID: 27226619 PMCID: PMC4946913 SCOPUS ID: 2-s2.0-84978431927 05/27/2016       15 Citations
  • HSF1 critically attunes proteotoxic stress sensing by mTORC1 to combat stress and promote growth. (Su KH, Cao J, Tang Z, Dai S, He Y, Sampson SB, Benjamin IJ, Dai C) Nat Cell Biol 2016 May;18(5):527-39 PMID: 27043084 PMCID: PMC5341796 SCOPUS ID: 2-s2.0-84962086158 04/05/2016       59 Citations
  • Characterization of the Cardiac Overexpression of HSPB2 Reveals Mitochondrial and Myogenic Roles Supported by a Cardiac HspB2 Interactome. (Grose JH, Langston K, Wang X, Squires S, Mustafi SB, Hayes W, Neubert J, Fischer SK, Fasano M, Saunders GM, Dai Q, Christians E, Lewandowski ED, Ping P, Benjamin IJ) PLoS One 2015;10(10):e0133994 PMID: 26465331 PMCID: PMC4605610 SCOPUS ID: 2-s2.0-84949034112 10/16/2015       10 Citations
  • Rescue of αB Crystallin (HSPB5) Mutants Associated Protein Aggregation by Co-Expression of HSPB5 Partners. (Hussein RM, Benjamin IJ, Kampinga HH) PLoS One 2015;10(5):e0126761 PMID: 25961584 PMCID: PMC4427338 SCOPUS ID: 2-s2.0-84930664227 05/12/2015       12 Citations
  • American Heart Association Cardiovascular Genome-Phenome Study: foundational basis and program. (Benjamin I, Brown N, Burke G, Correa A, Houser SR, Jones DW, Loscalzo J, Vasan RS, Whitman GR) Circulation 2015 Jan 06;131(1):100-12 PMID: 25411155 PMCID: PMC4286232 SCOPUS ID: 2-s2.0-84927762327 11/21/2014       22 Citations
  • A near-infrared fluorescent voltage-sensitive dye allows for moderate-throughput electrophysiological analyses of human induced pluripotent stem cell-derived cardiomyocytes. (Lopez-Izquierdo A, Warren M, Riedel M, Cho S, Lai S, Lux RL, Spitzer KW, Benjamin IJ, Tristani-Firouzi M, Jou CJ) Am J Physiol Heart Circ Physiol 2014 Nov 01;307(9):H1370-7 PMID: 25172899 PMCID: PMC4217013 SCOPUS ID: 2-s2.0-84908375059 08/31/2014       30 Citations
  • Functional and pharmacological analysis of cardiomyocytes differentiated from human peripheral blood mononuclear-derived pluripotent stem cells. (Riedel M, Jou CJ, Lai S, Lux RL, Moreno AP, Spitzer KW, Christians E, Tristani-Firouzi M, Benjamin IJ) Stem Cell Reports 2014 Jul 08;3(1):131-41 PMID: 25068127 PMCID: PMC4110777 SCOPUS ID: 2-s2.0-84904258538 07/30/2014       33 Citations
  • A near-infrared fluorescent voltage-sensitive dye allows for moderate-throughput analyses of human induced pluripotent stem cell-derived cardiomyocytes (Angelica Lopez-Izquierdo, Mark Warren, Michael Reidel, Scott Cho, Shuping Lai, Robert Lux, Kenneth Spitzer, Ivor Benjamin, Martin Tristani-Firouzi, and Chuanchau Jou) American Journal of Physiology - Heart and Circulatory Physiology 05/20/2014    
  • Chaperones and cardiac misfolding protein diseases. (Christians ES, Mustafi SB, Benjamin IJ) Curr Protein Pept Sci 2014 May;15(3):189-204 PMID: 24694370 SCOPUS ID: 2-s2.0-84904469376 04/04/2014       17 Citations
  • Molecular stress-inducing compounds increase osteoclast formation in a heat shock factor 1 protein-dependent manner. (Chai RC, Kouspou MM, Lang BJ, Nguyen CH, van der Kraan AG, Vieusseux JL, Lim RC, Gillespie MT, Benjamin IJ, Quinn JM, Price JT) J Biol Chem 2014 May 09;289(19):13602-14 PMID: 24692538 PMCID: PMC4036365 SCOPUS ID: 2-s2.0-84900416874 04/03/2014       16 Citations
  • Predictors of mortality and major in-hospital adverse events associated with electrophysiology catheter ablation. (Curley M, Berger M, Roth J, Benjamin I, Rubenstein J) JAMA Intern Med 2014 May;174(5):815-7 PMID: 24686853 SCOPUS ID: 2-s2.0-84899873057 04/02/2014       6 Citations
  • Sulphoxythiocarbamates modify cysteine residues in HSP90 causing degradation of client proteins and inhibition of cancer cell proliferation. (Zhang Y, Dayalan Naidu S, Samarasinghe K, Van Hecke GC, Pheely A, Boronina TN, Cole RN, Benjamin IJ, Cole PA, Ahn YH, Dinkova-Kostova AT) Br J Cancer 2014 Jan 07;110(1):71-82 PMID: 24322890 PMCID: PMC3887302 SCOPUS ID: 2-s2.0-84891848414 12/11/2013       25 Citations
  • ROS stress resets circadian clocks to coordinate pro-survival signals. (Tamaru T, Hattori M, Ninomiya Y, Kawamura G, Varès G, Honda K, Mishra DP, Wang B, Benjamin I, Sassone-Corsi P, Ozawa T, Takamatsu K) PLoS One 2013;8(12):e82006 PMID: 24312621 PMCID: PMC3846904 SCOPUS ID: 2-s2.0-84891440383 12/07/2013       76 Citations
  • Aggregate-prone R120GCRYAB triggers multifaceted modifications of the thioredoxin system. (Banerjee Mustafi S, Grose JH, Zhang H, Pratt GW, Sadoshima J, Christians ES, Benjamin IJ) Antioxid Redox Signal 2014 Jun 20;20(18):2891-906 PMID: 24180415 PMCID: PMC4039002 SCOPUS ID: 2-s2.0-84901639700 11/05/2013       9 Citations
  • Malfolded protein structure and proteostasis in lung diseases. (Balch WE, Sznajder JI, Budinger S, Finley D, Laposky AD, Cuervo AM, Benjamin IJ, Barreiro E, Morimoto RI, Postow L, Weissman AM, Gail D, Banks-Schlegel S, Croxton T, Gan W) Am J Respir Crit Care Med 2014 Jan 01;189(1):96-103 PMID: 24033344 PMCID: PMC3919126 SCOPUS ID: 2-s2.0-84891868645 09/17/2013       52 Citations
  • Heart Failure (Benjamin IJ) Genomic and Personalized Medicine 2013;2:540-556 SCOPUS ID: 2-s2.0-84883951500 08/29/2013    
  • Effects of redox state on the efficient uptake of cell permeable Peptide in Mammalian cells. (Squires S, Christians E, Riedel M, Timothy D, Rodesch CK, Marvin J, Benjamin I) Open Biochem J 2013;7:54-65 PMID: 23919090 PMCID: PMC3731798 SCOPUS ID: 2-s2.0-84884181980 08/07/2013       3 Citations
  • The NADPH metabolic network regulates human αB-crystallin cardiomyopathy and reductive stress in Drosophila melanogaster. (Xie HB, Cammarato A, Rajasekaran NS, Zhang H, Suggs JA, Lin HC, Bernstein SI, Benjamin IJ, Golic KG) PLoS Genet 2013 Jun;9(6):e1003544 PMID: 23818860 PMCID: PMC3688542 SCOPUS ID: 2-s2.0-84879656305 07/03/2013       23 Citations
  • Modeling human protein aggregation cardiomyopathy using murine induced pluripotent stem cells. (Limphong P, Zhang H, Christians E, Liu Q, Riedel M, Ivey K, Cheng P, Mitzelfelt K, Taylor G, Winge D, Srivastava D, Benjamin I) Stem Cells Transl Med 2013 Mar;2(3):161-6 PMID: 23430692 PMCID: PMC3659767 SCOPUS ID: 2-s2.0-84875084855 02/23/2013       7 Citations
  • Heart Failure (Benjamin IJ) Genomic and Personalized Medicine 15 November 2012:540-556 SCOPUS ID: 2-s2.0-85136954908 11/15/2012    
  • Reductive stress linked to small HSPs, G6PD, and Nrf2 pathways in heart disease. (Brewer AC, Mustafi SB, Murray TV, Rajasekaran NS, Benjamin IJ) Antioxid Redox Signal 2013 Mar 20;18(9):1114-27 PMID: 22938199 PMCID: PMC3567781 SCOPUS ID: 2-s2.0-84874052914 09/04/2012       97 Citations
  • HSPB2 is dispensable for the cardiac hypertrophic response but reduces mitochondrial energetics following pressure overload in mice. (Ishiwata T, Orosz A, Wang X, Mustafi SB, Pratt GW, Christians ES, Boudina S, Abel ED, Benjamin IJ) PLoS One 2012;7(8):e42118 PMID: 22870288 PMCID: PMC3411653 SCOPUS ID: 2-s2.0-84864755799 08/08/2012       17 Citations
  • Infiltrative and Protein Misfolding Myocardial Diseases (Gillespie HS, Benjamin IJ) Muscle: Fundamental Biology and Mechanisms of Disease 18 July 2012;1-2:625-637 SCOPUS ID: 2-s2.0-84882919160 07/18/2012    
  • Small heat shock proteins in redox metabolism: implications for cardiovascular diseases. (Christians ES, Ishiwata T, Benjamin IJ) Int J Biochem Cell Biol 2012 Oct;44(10):1632-45 PMID: 22710345 PMCID: PMC3412898 SCOPUS ID: 2-s2.0-84864437102 06/20/2012       57 Citations
  • Targeting endoglin, an auxiliary transforming growth factor β coreceptor, to prevent fibrosis and heart failure. (Benjamin IJ) Circulation 2012 Jun 05;125(22):2689-91 PMID: 22592899 PMCID: PMC3401168 SCOPUS ID: 2-s2.0-84861863431 05/18/2012       9 Citations
  • The heat shock transcription factor Hsf1 is downregulated in DNA damage-associated senescence, contributing to the maintenance of senescence phenotype. (Kim G, Meriin AB, Gabai VL, Christians E, Benjamin I, Wilson A, Wolozin B, Sherman MY) Aging Cell 2012 Aug;11(4):617-27 PMID: 22510478 PMCID: PMC3433748 SCOPUS ID: 2-s2.0-84863992349 04/19/2012       62 Citations
  • Heat shock transcription factor Hsf1 is involved in tumor progression via regulation of hypoxia-inducible factor 1 and RNA-binding protein HuR. (Gabai VL, Meng L, Kim G, Mills TA, Benjamin IJ, Sherman MY) Mol Cell Biol 2012 Mar;32(5):929-40 PMID: 22215620 PMCID: PMC3295200 SCOPUS ID: 2-s2.0-84857169594 01/05/2012       86 Citations
  • Glutathione-dependent reductive stress triggers mitochondrial oxidation and cytotoxicity. (Zhang H, Limphong P, Pieper J, Liu Q, Rodesch CK, Christians E, Benjamin IJ) FASEB J 2012 Apr;26(4):1442-51 PMID: 22202674 PMCID: PMC3316899 SCOPUS ID: 2-s2.0-84860904314 12/29/2011       150 Citations
  • HspB5 (CryAB; αB-crystallin) and protein aggregation cardiomyopathy (Zhang H, Benjamin IJ) Small Stress Proteins and Human Diseases 2011:287-300 SCOPUS ID: 2-s2.0-84895351040 12/01/2011    
  • HSF1-dependent upregulation of Hsp70 by sulfhydryl-reactive inducers of the KEAP1/NRF2/ARE pathway. (Zhang Y, Ahn YH, Benjamin IJ, Honda T, Hicks RJ, Calabrese V, Cole PA, Dinkova-Kostova AT) Chem Biol 2011 Nov 23;18(11):1355-61 PMID: 22118669 PMCID: PMC3302153 SCOPUS ID: 2-s2.0-82255181180 11/29/2011       92 Citations
  • Proteostasis and REDOX state in the heart. (Christians ES, Benjamin IJ) Am J Physiol Heart Circ Physiol 2012 Jan 01;302(1):H24-37 PMID: 22003057 PMCID: PMC3334238 SCOPUS ID: 2-s2.0-84255167180 10/18/2011       58 Citations
  • Synchronization of circadian Per2 rhythms and HSF1-BMAL1:CLOCK interaction in mouse fibroblasts after short-term heat shock pulse. (Tamaru T, Hattori M, Honda K, Benjamin I, Ozawa T, Takamatsu K) PLoS One 2011;6(9):e24521 PMID: 21915348 PMCID: PMC3168500 SCOPUS ID: 2-s2.0-80052527071 09/15/2011       89 Citations
  • Sustained activation of nuclear erythroid 2-related factor 2/antioxidant response element signaling promotes reductive stress in the human mutant protein aggregation cardiomyopathy in mice. (Rajasekaran NS, Varadharaj S, Khanderao GD, Davidson CJ, Kannan S, Firpo MA, Zweier JL, Benjamin IJ) Antioxid Redox Signal 2011 Mar 15;14(6):957-71 PMID: 21126175 PMCID: PMC3113450 SCOPUS ID: 2-s2.0-79951918162 12/04/2010       112 Citations
  • Heart Failure in the Era of Genomic Medicine (Benjamin IJ, Patel J) Essentials of Genomic and Personalized Medicine 2010:313-325 SCOPUS ID: 2-s2.0-84882782366 12/01/2010    
  • Selective degradation of aggregate-prone CryAB mutants by HSPB1 is mediated by ubiquitin-proteasome pathways. (Zhang H, Rajasekaran NS, Orosz A, Xiao X, Rechsteiner M, Benjamin IJ) J Mol Cell Cardiol 2010 Dec;49(6):918-30 PMID: 20863832 PMCID: PMC2975794 SCOPUS ID: 2-s2.0-78149416783 09/25/2010       42 Citations
  • Involvement of reductive stress in the cardiomyopathy in transgenic mice with cardiac-specific overexpression of heat shock protein 27. (Zhang X, Min X, Li C, Benjamin IJ, Qian B, Zhang X, Ding Z, Gao X, Yao Y, Ma Y, Cheng Y, Liu L) Hypertension 2010 Jun;55(6):1412-7 PMID: 20439823 SCOPUS ID: 2-s2.0-77953125913 05/05/2010       92 Citations
  • HSPB5 (Cryab; αB-Crystallin) and protein aggregation cardiomyopathy (Zhang H, Benjamin IJ) Small Stress Proteins and Human Diseases 1 January 2010:287-300 SCOPUS ID: 2-s2.0-85019892876 01/01/2010    
  • Heart Failure in the Era of Genomic Medicine (Benjamin IJ, Patel J) Genomic and Personalized Medicine, Two-Vol Set 2009:692-704 SCOPUS ID: 2-s2.0-84884763075 12/01/2009       1 Citation
  • Febrile-range temperature modifies cytokine gene expression in LPS-stimulated macrophages by differentially modifying NF-{kappa}B recruitment to cytokine gene promoters. (Cooper ZA, Ghosh A, Gupta A, Maity T, Benjamin IJ, Vogel SN, Hasday JD, Singh IS) Am J Physiol Cell Physiol 2010 Jan;298(1):C171-81 PMID: 19846753 PMCID: PMC2806152 SCOPUS ID: 2-s2.0-73549123428 10/23/2009       34 Citations
  • Heart Failure in the Era of Genomic Medicine (Benjamin IJ, Patel J) Genomic and Personalized Medicine: V1-2 11 November 2008:692-704 SCOPUS ID: 2-s2.0-85137073447 11/11/2008    
  • Reductive stress on life span extension in C. elegans. (Ralser M, Benjamin IJ) BMC Res Notes 2008 Jun 04;1:19 PMID: 18710529 PMCID: PMC2518267 SCOPUS ID: 2-s2.0-67650936587 08/20/2008       19 Citations
  • Global expression profiling identifies a novel biosignature for protein aggregation R120GCryAB cardiomyopathy in mice. (Rajasekaran NS, Firpo MA, Milash BA, Weiss RB, Benjamin IJ) Physiol Genomics 2008 Oct 08;35(2):165-72 PMID: 18628338 PMCID: PMC2575954 SCOPUS ID: 2-s2.0-57049087658 07/17/2008       23 Citations
  • Autophagy is an adaptive response in desmin-related cardiomyopathy. (Tannous P, Zhu H, Johnstone JL, Shelton JM, Rajasekaran NS, Benjamin IJ, Nguyen L, Gerard RD, Levine B, Rothermel BA, Hill JA) Proc Natl Acad Sci U S A 2008 Jul 15;105(28):9745-50 PMID: 18621691 PMCID: PMC2474535 SCOPUS ID: 2-s2.0-47749125013 07/16/2008       215 Citations
  • Heat shock co-activates interleukin-8 transcription. (Singh IS, Gupta A, Nagarsekar A, Cooper Z, Manka C, Hester L, Benjamin IJ, He JR, Hasday JD) Am J Respir Cell Mol Biol 2008 Aug;39(2):235-42 PMID: 18367728 PMCID: PMC2542457 SCOPUS ID: 2-s2.0-48649092274 03/28/2008       51 Citations
  • Differential display of DNA-binding proteins reveals heat-shock factor 1 as a circadian transcription factor. (Reinke H, Saini C, Fleury-Olela F, Dibner C, Benjamin IJ, Schibler U) Genes Dev 2008 Feb 01;22(3):331-45 PMID: 18245447 PMCID: PMC2216693 SCOPUS ID: 2-s2.0-38949209515 02/05/2008       182 Citations
  • CRYAB and HSPB2 deficiency alters cardiac metabolism and paradoxically confers protection against myocardial ischemia in aging mice. (Benjamin IJ, Guo Y, Srinivasan S, Boudina S, Taylor RP, Rajasekaran NS, Gottlieb R, Wawrousek EF, Abel ED, Bolli R) Am J Physiol Heart Circ Physiol 2007 Nov;293(5):H3201-9 PMID: 17873008 PMCID: PMC3683980 SCOPUS ID: 2-s2.0-36149001329 09/18/2007       44 Citations
  • Unmasking different mechanical and energetic roles for the small heat shock proteins CryAB and HSPB2 using genetically modified mouse hearts. (Pinz I, Robbins J, Rajasekaran NS, Benjamin IJ, Ingwall JS) FASEB J 2008 Jan;22(1):84-92 PMID: 17846079 SCOPUS ID: 2-s2.0-38049170987 09/12/2007       39 Citations
  • Human alpha B-crystallin mutation causes oxido-reductive stress and protein aggregation cardiomyopathy in mice. (Rajasekaran NS, Connell P, Christians ES, Yan LJ, Taylor RP, Orosz A, Zhang XQ, Stevenson TJ, Peshock RM, Leopold JA, Barry WH, Loscalzo J, Odelberg SJ, Benjamin IJ) Cell 2007 Aug 10;130(3):427-39 PMID: 17693254 PMCID: PMC2962423 SCOPUS ID: 2-s2.0-34547681313 08/19/2007       384 Citations
  • Induction of KLF4 in response to heat stress. (Liu Y, Wang J, Yi Y, Zhang H, Liu J, Liu M, Yuan C, Tang D, Benjamin IJ, Xiao X) Cell Stress Chaperones 2006;11(4):379-89 PMID: 17278886 PMCID: PMC1712684 SCOPUS ID: 2-s2.0-33947582095 02/07/2007       31 Citations
  • Erratum: Heat shock protein-70 mediates the cytoprotective effect of carbon monoxide: Involvement of p38β MAPK and heat shock factor-1 (Journal of Immunology (2005) 175 (2622-2629)) (Kim HP, Wang X, Zhang J, Suh GY, Benjamin IJ, Ryter SW, Choi AMK) Journal of Immunology 1 September 2006;177(5):3494 SCOPUS ID: 2-s2.0-33747791699 09/01/2006    
  • Viewing a stressful episode of ER: is ATF6 the triage nurse? (Benjamin IJ) Circ Res 2006 May 12;98(9):1120-2 PMID: 16690892 SCOPUS ID: 2-s2.0-33745052932 05/13/2006       15 Citations
  • CRYAB and HSPB2 deficiency increases myocyte mitochondrial permeability transition and mitochondrial calcium uptake. (Kadono T, Zhang XQ, Srinivasan S, Ishida H, Barry WH, Benjamin IJ) J Mol Cell Cardiol 2006 Jun;40(6):783-9 PMID: 16678848 SCOPUS ID: 2-s2.0-33744541387 05/09/2006       51 Citations
  • Heat shock response: lessons from mouse knockouts. (Christians ES, Benjamin IJ) Handb Exp Pharmacol 2006(172):139-52 PMID: 16610358 SCOPUS ID: 2-s2.0-33645995134 04/14/2006       27 Citations
  • RANK ligand expression in heat shock factor-2 deficient mouse bone marrow stromal/preosteoblast cells. (Kajiya H, Ito M, Ohshima H, Kenmotsu S, Ries WL, Benjamin IJ, Reddy SV) J Cell Biochem 2006 Apr 15;97(6):1362-9 PMID: 16365894 SCOPUS ID: 2-s2.0-33645657652 12/21/2005       10 Citations
  • A murine world without HSFs: meeting report. (Christians E, Benjamin IJ) Cell Stress Chaperones 2005;10(4):265-7 PMID: 16333980 PMCID: PMC1283871 SCOPUS ID: 2-s2.0-29144460939 12/13/2005       1 Citation
  • Heat shock protein-70 mediates the cytoprotective effect of carbon monoxide: involvement of p38 beta MAPK and heat shock factor-1. (Kim HP, Wang X, Zhang J, Suh GY, Benjamin IJ, Ryter SW, Choi AM) J Immunol 2005 Aug 15;175(4):2622-9 PMID: 16081837 SCOPUS ID: 2-s2.0-23444437384 08/06/2005       131 Citations
  • Induction of heat shock proteins by heregulin beta1 leads to protection from apoptosis and anchorage-independent growth. (Khaleque MA, Bharti A, Sawyer D, Gong J, Benjamin IJ, Stevenson MA, Calderwood SK) Oncogene 2005 Sep 29;24(43):6564-73 PMID: 16007186 SCOPUS ID: 2-s2.0-26944442444 07/12/2005       91 Citations
  • Heat shock factor 1-deficient mice exhibit decreased recovery of hearing following noise overstimulation. (Fairfield DA, Lomax MI, Dootz GA, Chen S, Galecki AT, Benjamin IJ, Dolan DF, Altschuler RA) J Neurosci Res 2005 Aug 15;81(4):589-96 PMID: 15952177 SCOPUS ID: 2-s2.0-24744469237 06/14/2005       36 Citations
  • Discovering the full spectrum of cardiovascular disease: Minority Health Summit 2003: report of the Basic Science Writing Group. (Benjamin IJ, Arnett DK, Loscalzo J, American Heart Association Basic Science Writing Group) Circulation 2005 Mar 15;111(10):e120-3 PMID: 15769753 SCOPUS ID: 2-s2.0-15244346693 03/17/2005       12 Citations
  • Learning from failure: congestive heart failure in the postgenomic age. (Benjamin IJ, Schneider MD) J Clin Invest 2005 Mar;115(3):495-9 PMID: 15765130 PMCID: PMC1052014 SCOPUS ID: 2-s2.0-14644404257 03/15/2005       57 Citations
  • Febrile-range hyperthermia augments neutrophil accumulation and enhances lung injury in experimental gram-negative bacterial pneumonia. (Rice P, Martin E, He JR, Frank M, DeTolla L, Hester L, O'Neill T, Manka C, Benjamin I, Nagarsekar A, Singh I, Hasday JD) J Immunol 2005 Mar 15;174(6):3676-85 PMID: 15749906 SCOPUS ID: 2-s2.0-20144377837 03/08/2005       93 Citations
  • Small heat shock proteins: a new classification scheme in mammals. (Taylor RP, Benjamin IJ) J Mol Cell Cardiol 2005 Mar;38(3):433-44 PMID: 15733903 SCOPUS ID: 2-s2.0-14744291911 03/01/2005       183 Citations
  • Mouse HSF1 disruption perturbs redox state and increases mitochondrial oxidative stress in kidney. (Yan LJ, Rajasekaran NS, Sathyanarayanan S, Benjamin IJ) Antioxid Redox Signal 2005;7(3-4):465-71 PMID: 15706094 SCOPUS ID: 2-s2.0-14044270113 02/12/2005       46 Citations
  • The stress or heat shock (HS) response: insights from transgenic mouse models. (Christians ES, Benjamin IJ) Methods 2005 Feb;35(2):170-5 PMID: 15649844 SCOPUS ID: 2-s2.0-11844295387 01/15/2005       13 Citations
  • Heat shock proteins in mammalian development. (Christians ES, Zhou Q, Renard J, Benjamin IJ) Semin Cell Dev Biol 2003 Oct;14(5):283-90 PMID: 14986858 SCOPUS ID: 2-s2.0-0742270277 02/28/2004       87 Citations
  • [Effects of hsf1 genotype on the constitutive expression of alphaB-crystallin in mice myocardium]. (Liu L, Zhang HH, Ding GX, Cheng YL, Yan LJ, Benjamin IJ) Zhongguo Ying Yong Sheng Li Xue Za Zhi 2004 Feb;20(1):30-3 PMID: 21162300 SCOPUS ID: 2-s2.0-84871946560 02/01/2004    
  • Use of Hsf1(-/-) mice reveals an essential role for HSF1 to protect lung against cadmium-induced injury. (Wirth D, Christians E, Li X, Benjamin IJ, Gustin P) Toxicol Appl Pharmacol 2003 Oct 01;192(1):12-20 PMID: 14554099 SCOPUS ID: 2-s2.0-0141671923 10/14/2003       25 Citations
  • Ivor J. Benjamin Named Chief of Cardiology at the University of Utah School of Medicine (Benjamin IJ) Journal of Investigative Medicine September 2003;51(5):245 SCOPUS ID: 2-s2.0-85181197601 09/01/2003    
  • Bimoclomol, a heat shock protein co-inducer, acts by the prolonged activation of heat shock factor-1. (Hargitai J, Lewis H, Boros I, Rácz T, Fiser A, Kurucz I, Benjamin I, Vígh L, Pénzes Z, Csermely P, Latchman DS) Biochem Biophys Res Commun 2003 Aug 01;307(3):689-95 PMID: 12893279 SCOPUS ID: 2-s2.0-0042170384 08/02/2003       123 Citations
  • Localized recruitment of a chromatin-remodeling activity by an activator in vivo drives transcriptional elongation. (Corey LL, Weirich CS, Benjamin IJ, Kingston RE) Genes Dev 2003 Jun 01;17(11):1392-401 PMID: 12782657 PMCID: PMC196071 SCOPUS ID: 2-s2.0-0038623298 06/05/2003       116 Citations
  • Heat shock factor 1-independent activation of dendritic cells by heat shock: implication for the uncoupling of heat-mediated immunoregulation from the heat shock response. (Zheng H, Benjamin IJ, Basu S, Li Z) Eur J Immunol 2003 Jun;33(6):1754-62 PMID: 12778494 SCOPUS ID: 2-s2.0-0037744720 06/05/2003       27 Citations
  • Heat shock transcription factor 2 is not essential for embryonic development, fertility, or adult cognitive and psychomotor function in mice. (McMillan DR, Christians E, Forster M, Xiao X, Connell P, Plumier JC, Zuo X, Richardson J, Morgan S, Benjamin IJ) Mol Cell Biol 2002 Nov;22(22):8005-14 PMID: 12391166 PMCID: PMC134743 SCOPUS ID: 2-s2.0-0036840377 10/23/2002       66 Citations
  • Mouse heat shock transcription factor 1 deficiency alters cardiac redox homeostasis and increases mitochondrial oxidative damage. (Yan LJ, Christians ES, Liu L, Xiao X, Sohal RS, Benjamin IJ) EMBO J 2002 Oct 01;21(19):5164-72 PMID: 12356732 PMCID: PMC129050 SCOPUS ID: 2-s2.0-0036790590 10/03/2002       200 Citations
  • Stress pathways in the rat cochlea and potential for protection from acquired deafness. (Altschuler RA, Fairfield D, Cho Y, Leonova E, Benjamin IJ, Miller JM, Lomax MI) Audiol Neurootol 2002;7(3):152-6 PMID: 12053136 SCOPUS ID: 2-s2.0-0036280975 06/08/2002       27 Citations
  • Exercise, estrogen, and ischemic cardioprotection by heat shock protein 70. (Benjamin IJ, Christians E) Circ Res 2002 May 03;90(8):833-5 PMID: 11988480 SCOPUS ID: 2-s2.0-0037013150 05/04/2002       19 Citations
  • Heat shock factor 1 and heat shock proteins: Critical partners in protection against acute cell injury. (Christians ES, Yan LJ, Benjamin IJ) Crit Care Med 2002 Jan;30(1 Supp):S43-S50 PMID: 11839944 02/13/2002    
  • Heat shock factor 1-mediated thermotolerance prevents cell death and results in G2/M cell cycle arrest. (Luft JC, Benjamin IJ, Mestril R, Dix DJ) Cell Stress Chaperones 2001 Oct;6(4):326-36 PMID: 11795469 PMCID: PMC434415 SCOPUS ID: 2-s2.0-0035204193 01/25/2002       48 Citations
  • Heat shock factor 1 and heat shock proteins: critical partners in protection against acute cell injury. (Christians ES, Yan LJ, Benjamin IJ) Crit Care Med 2002 Jan;30(1 Suppl):S43-50 PMID: 11782560 SCOPUS ID: 2-s2.0-0036160052 01/10/2002       188 Citations
  • Matrix metalloproteinases: from biology to therapeutic strategies in cardiovascular disease. (Benjamin IJ) J Investig Med 2001 Sep;49(5):381-97 PMID: 11523694 SCOPUS ID: 2-s2.0-0034888802 08/29/2001       43 Citations
  • Maternal effect of Hsf1 on reproductive success. (Christians E, Davis AA, Thomas SD, Benjamin IJ) Nature 2000 Oct 12;407(6805):693-4 PMID: 11048707 SCOPUS ID: 2-s2.0-0034641933 10/26/2000       235 Citations
  • Protective responses in the ischemic myocardium. (Williams RS, Benjamin IJ) J Clin Invest 2000 Oct;106(7):813-8 PMID: 11018066 PMCID: PMC381426 SCOPUS ID: 2-s2.0-0033797702 10/06/2000       110 Citations
  • Induction of a heat shock factor 1-dependent stress response alters the cytotoxic activity of hsp90-binding agents. (Bagatell R, Paine-Murrieta GD, Taylor CW, Pulcini EJ, Akinaga S, Benjamin IJ, Whitesell L) Clin Cancer Res 2000 Aug;6(8):3312-8 PMID: 10955818 SCOPUS ID: 2-s2.0-0033890818 08/24/2000       244 Citations
  • Disruption of heat shock factor 1 reveals an essential role in the ubiquitin proteolytic pathway. (Pirkkala L, Alastalo TP, Zuo X, Benjamin IJ, Sistonen L) Mol Cell Biol 2000 Apr;20(8):2670-5 PMID: 10733569 PMCID: PMC85482 SCOPUS ID: 2-s2.0-0034069656 03/25/2000       99 Citations
  • HSF1 is required for extra-embryonic development, postnatal growth and protection during inflammatory responses in mice. (Xiao X, Zuo X, Davis AA, McMillan DR, Curry BB, Richardson JA, Benjamin IJ) EMBO J 1999 Nov 01;18(21):5943-52 PMID: 10545106 PMCID: PMC1171660 SCOPUS ID: 2-s2.0-0033229880 11/02/1999       467 Citations
  • Diabetes and cardiovascular disease: a statement for healthcare professionals from the American Heart Association. (Grundy SM, Benjamin IJ, Burke GL, Chait A, Eckel RH, Howard BV, Mitch W, Smith SC Jr, Sowers JR) Circulation 1999 Sep 07;100(10):1134-46 PMID: 10477542 SCOPUS ID: 2-s2.0-0033533596 09/08/1999       1730 Citations
  • Stress-response proteins in cardiovascular disease. (Xiao X, Benjamin IJ) Am J Hum Genet 1999 Mar;64(3):685-90 PMID: 10053001 PMCID: PMC1377784 SCOPUS ID: 2-s2.0-0033361928 03/03/1999       33 Citations
  • Stress (heat shock) proteins: molecular chaperones in cardiovascular biology and disease. (Benjamin IJ, McMillan DR) Circ Res 1998 Jul 27;83(2):117-32 PMID: 9686751 SCOPUS ID: 2-s2.0-0032572603 08/01/1998       802 Citations
  • Targeted disruption of heat shock transcription factor 1 abolishes thermotolerance and protection against heat-inducible apoptosis. (McMillan DR, Xiao X, Shao L, Graves K, Benjamin IJ) J Biol Chem 1998 Mar 27;273(13):7523-8 PMID: 9516453 SCOPUS ID: 2-s2.0-0032571397 04/29/1998       444 Citations
  • Immuno and functional characterization of CFTR in submandibular and pancreatic acinar and duct cells. (Zeng W, Lee MG, Yan M, Diaz J, Benjamin I, Marino CR, Kopito R, Freedman S, Cotton C, Muallem S, Thomas P) Am J Physiol 1997 Aug;273(2 Pt 1):C442-55 PMID: 9277342 SCOPUS ID: 2-s2.0-0000903375 08/01/1997       124 Citations
  • Temporospatial expression of the small HSP/alpha B-crystallin in cardiac and skeletal muscle during mouse development. (Benjamin IJ, Shelton J, Garry DJ, Richardson JA) Dev Dyn 1997 Jan;208(1):75-84 PMID: 8989522 SCOPUS ID: 2-s2.0-0031031926 01/01/1997       73 Citations
  • Continuous contractile activity induces fiber type specific expression of HSP70 in skeletal muscle. (Neufer PD, Ordway GA, Hand GA, Shelton JM, Richardson JA, Benjamin IJ, Williams RS) Am J Physiol 1996 Dec;271(6 Pt 1):C1828-37 PMID: 8997182 SCOPUS ID: 2-s2.0-0030465870 12/01/1996       79 Citations
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