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Jonathan S. Marchant PhD

Jonathan S. Marchant PhD

Chair, Professor

Institution: Medical College of Wisconsin
Department: Cell Biology, Neurobiology and Anatomy
Program: Administration

Member of the Genomic Sciences and Precision Medicine Center (GSPMC)

Research Experience

  • Anthelmintics
  • Calcium Channels
  • Calcium Signaling
  • Endoplasmic Reticulum
  • Inositol 1,4,5-Trisphosphate Receptors
  • Lysosomes
  • Microscopy, Confocal
  • Planarians
  • Receptors, G-Protein-Coupled
  • Regeneration
  • Schistosomiasis
  • Publications

  • Unique pharmacological properties of serotoninergic G-protein coupled receptors from cestodes. (Camicia F, Celentano AM, Johns ME, Chan JD, Maldonado L, Vaca H, Di Siervi N, Kamentezky L, Gamo AM, Ortega-Gutierrez S, Martin-Fontecha M, Davio C, Marchant JS, Rosenzvit MC) PLoS Negl Trop Dis 2018 Feb;12(2):e0006267 PMID: 29425245 PMCID: PMC5823469 02/10/2018
  • The anthelmintic praziquantel is a human serotoninergic G-protein-coupled receptor ligand. (Chan JD, Cupit PM, Gunaratne GS, McCorvy JD, Yang Y, Stoltz K, Webb TR, Dosa PI, Roth BL, Abagyan R, Cunningham C, Marchant JS) Nat Commun 2017 Dec 05;8(1):1910 PMID: 29208933 PMCID: PMC5716991 12/07/2017
  • Heterologous Protein Expression in the Oocyte. (Marchant JS) Cold Spring Harb Protoc 2018 Apr 02;2018(4):pdb.prot096990 PMID: 29208643 12/07/2017
  • Inhibition of intestinal ascorbic acid uptake by lipopolysaccharide is mediated via transcriptional mechanisms. (Subramanian VS, Sabui S, Moradi H, Marchant JS, Said HM) Biochim Biophys Acta 2018 02;1860(2):556-565 PMID: 29030247 PMCID: PMC5732882 10/17/2017
  • Molecular mechanism(s) involved in differential expression of vitamin C transporters along the intestinal tract. (Subramanian VS, Srinivasan P, Wildman AJ, Marchant JS, Said HM) Am J Physiol Gastrointest Liver Physiol 2017 Apr 01;312(4):G340-G347 PMID: 27932501 PMCID: PMC5407060 12/10/2016
  • Dataset for a de novo transcriptome assembly, utilized for defining the voltage-gated like ion channel superfamily. (Chan JD, Zhang D, Liu X, Zarowiecki MZ, Berriman M, Marchant JS) Data Brief 2016 Dec;9:1044-1047 PMID: 27909700 PMCID: PMC5124351 12/03/2016
  • Utilizing the planarian voltage-gated ion channel transcriptome to resolve a role for a Ca channel in neuromuscular function and regeneration. (Chan JD, Zhang D, Liu X, Zarowiecki M, Berriman M, Marchant JS) Biochim Biophys Acta 2017 06;1864(6):1036-1045 PMID: 27771293 PMCID: PMC5397384 10/25/2016
  • Kinetic profiling an abundantly expressed planarian serotonergic GPCR identifies bromocriptine as a perdurant antagonist. (Chan JD, Grab T, Marchant JS) Int J Parasitol Drugs Drug Resist 2016 12;6(3):356-363 PMID: 27397764 PMCID: PMC5196488 07/12/2016
  • Pharmacological profiling an abundantly expressed schistosome serotonergic GPCR identifies nuciferine as a potent antagonist. (Chan JD, Acharya S, Day TA, Marchant JS) Int J Parasitol Drugs Drug Resist 2016 12;6(3):364-370 PMID: 27397763 PMCID: PMC5196489 07/12/2016
  • A Miniaturized Screen of a Schistosoma mansoni Serotonergic G Protein-Coupled Receptor Identifies Novel Classes of Parasite-Selective Inhibitors. (Chan JD, McCorvy JD, Acharya S, Johns ME, Day TA, Roth BL, Marchant JS) PLoS Pathog 2016 May;12(5):e1005651 PMID: 27187180 PMCID: PMC4871480 05/18/2016
  • Ergot Alkaloids (Re)generate New Leads as Antiparasitics. (Chan JD, Agbedanu PN, Grab T, Zamanian M, Dosa PI, Day TA, Marchant JS) PLoS Negl Trop Dis 2015;9(9):e0004063 PMID: 26367744 PMCID: PMC4569474 09/15/2015
  • Two-pore channels at the intersection of endolysosomal membrane traffic. (Marchant JS, Patel S) Biochem Soc Trans 2015 Jun;43(3):434-41 PMID: 26009187 PMCID: PMC4730950 05/27/2015
  • TPC1 Knockout Knocks Out TPC1. (Hooper R, Churamani D, Davidson SM, Lin-Moshier Y, Walseth TF, Patel S, Marchant JS) Mol Cell Biol 2015 May;35(10):1882-3 PMID: 25900974 PMCID: PMC4405651 04/23/2015
  • Modulation of elementary calcium release mediates a transition from puffs to waves in an IP3R cluster model. (Rückl M, Parker I, Marchant JS, Nagaiah C, Johenning FW, Rüdiger S) PLoS Comput Biol 2015 Jan;11(1):e1003965 PMID: 25569772 PMCID: PMC4288706 01/09/2015
  • Dysregulation of lysosomal morphology by pathogenic LRRK2 is corrected by TPC2 inhibition. (Hockey LN, Kilpatrick BS, Eden ER, Lin-Moshier Y, Brailoiu GC, Brailoiu E, Futter CE, Schapira AH, Marchant JS, Patel S) J Cell Sci 2015 Jan 15;128(2):232-8 PMID: 25416817 PMCID: PMC4294771 11/25/2014
  • The Two-pore channel (TPC) interactome unmasks isoform-specific roles for TPCs in endolysosomal morphology and cell pigmentation. (Lin-Moshier Y, Keebler MV, Hooper R, Boulware MJ, Liu X, Churamani D, Abood ME, Walseth TF, Brailoiu E, Patel S, Marchant JS) Proc Natl Acad Sci U S A 2014 Sep 09;111(36):13087-92 PMID: 25157141 PMCID: PMC4246952 08/27/2014
  • Making heads or tails: planarian stem cells in the classroom. (Srougi MC, Thomas-Swanik J, Chan JD, Marchant JS, Carson S) J Microbiol Biol Educ 2014 May;15(1):18-25 PMID: 24839511 PMCID: PMC4004734 05/20/2014
  • Questioning regulation of two-pore channels by NAADP. (Marchant JS, Patel S) Messenger (Los Angel) 2013 Jun 01;2(2):113-119 PMID: 24829847 PMCID: PMC4018199 05/16/2014
  • 'Death and axes': unexpected Ca²⁺ entry phenologs predict new anti-schistosomal agents. (Chan JD, Agbedanu PN, Zamanian M, Gruba SM, Haynes CL, Day TA, Marchant JS) PLoS Pathog 2014 Feb;10(2):e1003942 PMID: 24586156 PMCID: PMC3930560 03/04/2014
  • Mitochondrial uptake of thiamin pyrophosphate: physiological and cell biological aspects. (Subramanian VS, Nabokina SM, Lin-Moshier Y, Marchant JS, Said HM) PLoS One 2013;8(8):e73503 PMID: 24023687 PMCID: PMC3758298 09/12/2013
  • Glyoxalate reductase/hydroxypyruvate reductase interacts with the sodium-dependent vitamin C transporter-1 to regulate cellular vitamin C homeostasis. (Subramanian VS, Nabokina SM, Patton JR, Marchant JS, Moradi H, Said HM) Am J Physiol Gastrointest Liver Physiol 2013 Jun 15;304(12):G1079-86 PMID: 23599041 PMCID: PMC3680717 04/20/2013
  • Characterization of a flatworm inositol (1,4,5) trisphosphate receptor (IP₃R) reveals a role in reproductive physiology. (Zhang D, Liu X, Chan JD, Marchant JS) Cell Calcium 2013 May-Jun;53(5-6):307-14 PMID: 23481272 PMCID: PMC3665645 03/14/2013
  • A rapid Western blotting protocol for the Xenopus oocyte. (Lin-Moshier Y, Marchant JS) Cold Spring Harb Protoc 2013 Mar 01;2013(3) PMID: 23457341 PMCID: PMC4017335 03/05/2013
  • Nuclear microinjection to assess how heterologously expressed proteins impact Ca2+ signals in Xenopus oocytes. (Lin-Moshier Y, Marchant JS) Cold Spring Harb Protoc 2013 Mar 01;2013(3) PMID: 23457340 PMCID: PMC4021487 03/05/2013
  • The Xenopus oocyte: a single-cell model for studying Ca2+ signaling. (Lin-Moshier Y, Marchant JS) Cold Spring Harb Protoc 2013 Mar 01;2013(3) PMID: 23457336 PMCID: PMC4017334 03/05/2013
  • Ca²⁺ channels and praziquantel: a view from the free world. (Chan JD, Zarowiecki M, Marchant JS) Parasitol Int 2013 Dec;62(6):619-28 PMID: 23246536 PMCID: PMC3610807 12/19/2012
  • Re-evaluation of the role of calcium homeostasis endoplasmic reticulum protein (CHERP) in cellular calcium signaling. (Lin-Moshier Y, Sebastian PJ, Higgins L, Sampson ND, Hewitt JE, Marchant JS) J Biol Chem 2013 Jan 04;288(1):355-67 PMID: 23148228 PMCID: PMC3537033 11/14/2012
  • Modulation of function of sodium-dependent vitamin C transporter 1 (SVCT1) by Rab8a in intestinal epithelial cells: studies utilizing Caco-2 cells and Rab8a knockout mice. (Subramanian VS, Subramanya SB, Ghosal A, Marchant JS, Harada A, Said HM) Dig Dis Sci 2013 Mar;58(3):641-9 PMID: 23014846 PMCID: PMC3547156 09/28/2012
  • The Molecular Basis for Ca Signalling by NAADP: Two-Pore Channels in a Complex? (Marchant JS, Lin-Moshier Y, Walseth TF, Patel S) Messenger (Los Angel) 2012 Jun 01;1(1):63-76 PMID: 25309835 PMCID: PMC4193953 06/01/2012
  • Nicotinic Acid Adenine Dinucleotide 2'-Phosphate (NAADP) Binding Proteins in T-Lymphocytes. (Walseth TF, Lin-Moshier Y, Weber K, Marchant JS, Slama JT, Guse AH) Messenger (Los Angel) 2012 Jun 01;1(1):86-94 PMID: 24829846 PMCID: PMC4017354 06/01/2012
  • Photoaffinity labeling of high affinity nicotinic acid adenine dinucleotide phosphate (NAADP)-binding proteins in sea urchin egg. (Walseth TF, Lin-Moshier Y, Jain P, Ruas M, Parrington J, Galione A, Marchant JS, Slama JT) J Biol Chem 2012 Jan 20;287(4):2308-15 PMID: 22117077 PMCID: PMC3268392 11/26/2011
  • Photoaffinity labeling of nicotinic acid adenine dinucleotide phosphate (NAADP) targets in mammalian cells. (Lin-Moshier Y, Walseth TF, Churamani D, Davidson SM, Slama JT, Hooper R, Brailoiu E, Patel S, Marchant JS) J Biol Chem 2012 Jan 20;287(4):2296-307 PMID: 22117075 PMCID: PMC3268391 11/26/2011
  • Opposing roles of voltage-gated Ca2+ channels in neuronal control of regenerative patterning. (Zhang D, Chan JD, Nogi T, Marchant JS) J Neurosci 2011 Nov 02;31(44):15983-95 PMID: 22049441 PMCID: PMC3380623 11/04/2011
  • Pharmacological and functional genetic assays to manipulate regeneration of the planarian Dugesia japonica. (Chan JD, Marchant JS) J Vis Exp 2011 Aug 31(54) PMID: 21897362 PMCID: PMC3217636 09/08/2011
  • Differential expression of human riboflavin transporters -1, -2, and -3 in polarized epithelia: a key role for hRFT-2 in intestinal riboflavin uptake. (Subramanian VS, Subramanya SB, Rapp L, Marchant JS, Ma TY, Said HM) Biochim Biophys Acta 2011 Dec;1808(12):3016-21 PMID: 21854757 PMCID: PMC3196270 08/23/2011
  • The endo-lysosomal system as an NAADP-sensitive acidic Ca(2+) store: role for the two-pore channels. (Patel S, Ramakrishnan L, Rahman T, Hamdoun A, Marchant JS, Taylor CW, Brailoiu E) Cell Calcium 2011 Aug;50(2):157-67 PMID: 21529939 PMCID: PMC3160778 05/03/2011
  • Role of cysteine residues in cell surface expression of the human riboflavin transporter-2 (hRFT2) in intestinal epithelial cells. (Subramanian VS, Rapp L, Marchant JS, Said HM) Am J Physiol Gastrointest Liver Physiol 2011 Jul;301(1):G100-9 PMID: 21512156 PMCID: PMC3129935 04/23/2011
  • Inositol (1,4,5)-trisphosphate receptor microarchitecture shapes Ca2+ puff kinetics. (Diambra L, Marchant JS) Biophys J 2011 Feb 16;100(4):822-31 PMID: 21320425 PMCID: PMC3037600 02/16/2011
  • Two-pore channels: Regulation by NAADP and customized roles in triggering calcium signals. (Patel S, Marchant JS, Brailoiu E) Cell Calcium 2010 Jun;47(6):480-90 PMID: 20621760 PMCID: PMC2921607 07/14/2010
  • An ancestral deuterostome family of two-pore channels mediates nicotinic acid adenine dinucleotide phosphate-dependent calcium release from acidic organelles. (Brailoiu E, Hooper R, Cai X, Brailoiu GC, Keebler MV, Dun NJ, Marchant JS, Patel S) J Biol Chem 2010 Jan 29;285(5):2897-901 PMID: 19940116 PMCID: PMC2823445 11/27/2009
  • Molecular determinants dictating cell surface expression of the human sodium-dependent vitamin C transporter-2 in human liver cells. (Subramanian VS, Marchant JS, Said HM) Am J Physiol Gastrointest Liver Physiol 2010 Feb;298(2):G267-74 PMID: 19926816 PMCID: PMC2822508 11/21/2009
  • Localization and socialization: experimental insights into the functional architecture of IP3 receptors. (Diambra L, Marchant JS) Chaos 2009 Sep;19(3):037103 PMID: 19792028 PMCID: PMC2771704 10/02/2009
  • Essential requirement for two-pore channel 1 in NAADP-mediated calcium signaling. (Brailoiu E, Churamani D, Cai X, Schrlau MG, Brailoiu GC, Gao X, Hooper R, Boulware MJ, Dun NJ, Marchant JS, Patel S) J Cell Biol 2009 Jul 27;186(2):201-9 PMID: 19620632 PMCID: PMC2717647 07/22/2009
  • Dual mechanisms of sHA 14-1 in inducing cell death through endoplasmic reticulum and mitochondria. (Hermanson D, Addo SN, Bajer AA, Marchant JS, Das SG, Srinivasan B, Al-Mousa F, Michelangeli F, Thomas DD, Lebien TW, Xing C) Mol Pharmacol 2009 Sep;76(3):667-78 PMID: 19561125 PMCID: PMC2730395 06/30/2009
  • A novel biological activity of praziquantel requiring voltage-operated Ca2+ channel beta subunits: subversion of flatworm regenerative polarity. (Nogi T, Zhang D, Chan JD, Marchant JS) PLoS Negl Trop Dis 2009 Jun 23;3(6):e464 PMID: 19554083 PMCID: PMC2694594 06/26/2009
  • Membrane targeting and intracellular trafficking of the human sodium-dependent multivitamin transporter in polarized epithelial cells. (Subramanian VS, Marchant JS, Boulware MJ, Ma TY, Said HM) Am J Physiol Cell Physiol 2009 Apr;296(4):C663-71 PMID: 19211916 PMCID: PMC2670647 02/13/2009
  • Molecular characterization of a novel cell surface ADP-ribosyl cyclase from the sea urchin. (Churamani D, Boulware MJ, Ramakrishnan L, Geach TJ, Martin AC, Vacquier VD, Marchant JS, Dale L, Patel S) Cell Signal 2008 Dec;20(12):2347-55 PMID: 18824228 PMCID: PMC4313535 10/01/2008
  • Timing in cellular Ca2+ signaling. (Boulware MJ, Marchant JS) Curr Biol 2008 Sep 09;18(17):R769-R776 PMID: 18786382 PMCID: PMC3236564 09/13/2008
  • N-Glycosylation is required for Na+-dependent vitamin C transporter functionality. (Subramanian VS, Marchant JS, Reidling JC, Said HM) Biochem Biophys Res Commun 2008 Sep 12;374(1):123-7 PMID: 18619416 PMCID: PMC2528843 07/16/2008
  • Nuclear pore disassembly from endoplasmic reticulum membranes promotes Ca2+ signalling competency. (Boulware MJ, Marchant JS) J Physiol 2008 Jun 15;586(12):2873-88 PMID: 18450775 PMCID: PMC2517208 05/03/2008
  • Enhanced Ca2+ leak from ER Ca2+ stores induced by hepatitis C NS5A protein. (Robinson LC, Marchant JS) Biochem Biophys Res Commun 2008 Apr 11;368(3):593-9 PMID: 18258181 PMCID: PMC2292798 02/09/2008
  • Apical membrane targeting and trafficking of the human proton-coupled transporter in polarized epithelia. (Subramanian VS, Marchant JS, Said HM) Am J Physiol Cell Physiol 2008 Jan;294(1):C233-40 PMID: 18003745 11/16/2007
  • Tight junction targeting and intracellular trafficking of occludin in polarized epithelial cells. (Subramanian VS, Marchant JS, Ye D, Ma TY, Said HM) Am J Physiol Cell Physiol 2007 Nov;293(5):C1717-26 PMID: 17855770 09/15/2007
  • Molecular characterization of a novel intracellular ADP-ribosyl cyclase. (Churamani D, Boulware MJ, Geach TJ, Martin AC, Moy GW, Su YH, Vacquier VD, Marchant JS, Dale L, Patel S) PLoS One 2007 Aug 29;2(8):e797 PMID: 17726527 PMCID: PMC1949048 08/30/2007
  • Vitamin B1 (thiamine) uptake by human retinal pigment epithelial (ARPE-19) cells: mechanism and regulation. (Subramanian VS, Mohammed ZM, Molina A, Marchant JS, Vaziri ND, Said HM) J Physiol 2007 Jul 01;582(Pt 1):73-85 PMID: 17463047 PMCID: PMC2075275 04/28/2007
  • The inositol 1,4,5-trisphosphate receptor (Itpr) gene family in Xenopus: identification of type 2 and type 3 inositol 1,4,5-trisphosphate receptor subtypes. (Zhang D, Boulware MJ, Pendleton MR, Nogi T, Marchant JS) Biochem J 2007 Jun 15;404(3):383-91 PMID: 17338679 PMCID: PMC1896291 03/07/2007
  • Targeting and intracellular trafficking of clinically relevant hTHTR1 mutations in human cell lines. (Subramanian VS, Marchant JS, Said HM) Clin Sci (Lond) 2007 Jul;113(2):93-102 PMID: 17331069 03/03/2007
  • Calcium influx: beyond 'current' biology. (Robinson LC, Marchant JS) Curr Biol 2006 Jul 25;16(14):R548-50 PMID: 16860734 07/25/2006
  • Biotin-responsive basal ganglia disease-linked mutations inhibit thiamine transport via hTHTR2: biotin is not a substrate for hTHTR2. (Subramanian VS, Marchant JS, Said HM) Am J Physiol Cell Physiol 2006 Nov;291(5):C851-9 PMID: 16790503 06/23/2006
  • Targeting and trafficking of the human thiamine transporter-2 in epithelial cells. (Subramanian VS, Marchant JS, Said HM) J Biol Chem 2006 Feb 24;281(8):5233-45 PMID: 16371350 12/24/2005
  • Cellular signalling: STIMulating calcium entry. (Marchant JS) Curr Biol 2005 Jul 12;15(13):R493-5 PMID: 16005278 07/12/2005
  • IP3 receptor activity is differentially regulated in endoplasmic reticulum subdomains during oocyte maturation. (Boulware MJ, Marchant JS) Curr Biol 2005 Apr 26;15(8):765-70 PMID: 15854911 04/28/2005
  • Improved "optical highlighter" probes derived from discosoma red fluorescent protein. (Robinson LC, Marchant JS) Biophys J 2005 Feb;88(2):1444-57 PMID: 15556986 PMCID: PMC1305146 11/24/2004
  • Calcium-dependent dephosphorylation mediates the hyperosmotic and lysophosphatidic acid-dependent inhibition of natriuretic peptide receptor-B/guanylyl cyclase-B. (Potthast R, Abbey-Hosch SE, Antos LK, Marchant JS, Kuhn M, Potter LR) J Biol Chem 2004 Nov 19;279(47):48513-9 PMID: 15371450 09/17/2004
  • A C-terminal region dictates the apical plasma membrane targeting of the human sodium-dependent vitamin C transporter-1 in polarized epithelia. (Subramanian VS, Marchant JS, Boulware MJ, Said HM) J Biol Chem 2004 Jun 25;279(26):27719-28 PMID: 15084584 04/16/2004
  • Expression and functional contribution of hTHTR-2 in thiamin absorption in human intestine. (Said HM, Balamurugan K, Subramanian VS, Marchant JS) Am J Physiol Gastrointest Liver Physiol 2004 Mar;286(3):G491-8 PMID: 14615284 11/15/2003
  • Polarized expression of members of the solute carrier SLC19A gene family of water-soluble multivitamin transporters: implications for physiological function. (Boulware MJ, Subramanian VS, Said HM, Marchant JS) Biochem J 2003 Nov 15;376(Pt 1):43-8 PMID: 14602044 PMCID: PMC1223768 11/07/2003
  • Cell biology of the human thiamine transporter-1 (hTHTR1). Intracellular trafficking and membrane targeting mechanisms. (Subramanian VS, Marchant JS, Parker I, Said HM) J Biol Chem 2003 Feb 07;278(6):3976-84 PMID: 12454006 11/28/2002
  • Intracellular trafficking and membrane targeting mechanisms of the human reduced folate carrier in Mammalian epithelial cells. (Marchant JS, Subramanian VS, Parker I, Said HM) J Biol Chem 2002 Sep 06;277(36):33325-33 PMID: 12087110 06/28/2002
  • Structural and functional relationships between Ca2+ puffs and mitochondria in Xenopus oocytes. (Marchant JS, Ramos V, Parker I) Am J Physiol Cell Physiol 2002 Jun;282(6):C1374-86 PMID: 11997252 05/09/2002
  • Intracellular trafficking/membrane targeting of human reduced folate carrier expressed in Xenopus oocytes. (Subramanian VS, Marchant JS, Parker I, Said HM) Am J Physiol Gastrointest Liver Physiol 2001 Dec;281(6):G1477-86 PMID: 11705753 11/14/2001
  • Multiphoton-evoked color change of DsRed as an optical highlighter for cellular and subcellular labeling. (Marchant JS, Stutzmann GE, Leissring MA, LaFerla FM, Parker I) Nat Biotechnol 2001 Jul;19(7):645-9 PMID: 11433276 07/04/2001
  • Xenopus tropicalis oocytes as an advantageous model system for the study of intracellular Ca(2+) signalling. (Marchant JS, Parker I) Br J Pharmacol 2001 Apr;132(7):1396-410 PMID: 11264232 PMCID: PMC1572681 03/27/2001
  • Role of elementary Ca(2+) puffs in generating repetitive Ca(2+) oscillations. (Marchant JS, Parker I) EMBO J 2001 Jan 15;20(1-2):65-76 PMID: 11226156 PMCID: PMC140189 02/28/2001
  • Functional interactions in Ca(2+) signaling over different time and distance scales. (Marchant JS, Parker I) J Gen Physiol 2000 Nov;116(5):691-6 PMID: 11055997 PMCID: PMC2229487 10/31/2000
  • Acyclophostin: a ribose-modified analog of adenophostin A with high affinity for inositol 1,4,5-trisphosphate receptors and pH-dependent efficacy. (Beecroft MD, Marchant JS, Riley AM, Van Straten NC, Van der Marel GA, Van Boom JH, Potter BV, Taylor CW) Mol Pharmacol 1999 Jan;55(1):109-17 PMID: 9882704 01/12/1999
  • Kinetics of elementary Ca2+ puffs evoked in Xenopus oocytes by different Ins(1,4,5)P3 receptor agonists. (Marchant JS, Parker I) Biochem J 1998 Sep 15;334 ( Pt 3):505-9 PMID: 9729454 PMCID: PMC1219715 09/08/1998
  • Rapid activation and partial inactivation of inositol trisphosphate receptors by inositol trisphosphate. (Marchant JS, Taylor CW) Biochemistry 1998 Aug 18;37(33):11524-33 PMID: 9708988 08/26/1998
  • Activation and co-ordination of InsP3-mediated elementary Ca2+ events during global Ca2+ signals in Xenopus oocytes. (Callamaras N, Marchant JS, Sun XP, Parker I) J Physiol 1998 May 15;509 ( Pt 1):81-91 PMID: 9547383 PMCID: PMC2230929 06/17/1998
  • A continuum of InsP3-mediated elementary Ca2+ signalling events in Xenopus oocytes. (Sun XP, Callamaras N, Marchant JS, Parker I) J Physiol 1998 May 15;509 ( Pt 1):67-80 PMID: 9547382 PMCID: PMC2230949 06/17/1998
  • Disaccharide polyphosphates based upon adenophostin A activate hepatic D-myo-inositol 1,4,5-trisphosphate receptors. (Marchant JS, Beecroft MD, Riley AM, Jenkins DJ, Marwood RD, Taylor CW, Potter BV) Biochemistry 1997 Oct 21;36(42):12780-90 PMID: 9335535 10/23/1997
  • Cooperative activation of IP3 receptors by sequential binding of IP3 and Ca2+ safeguards against spontaneous activity. (Marchant JS, Taylor CW) Curr Biol 1997 Jul 01;7(7):510-8 PMID: 9210378 07/01/1997
  • Rapid kinetic measurements of 45Ca2+ mobilization reveal that Ins(2,4,5)P3 is a partial agonist at hepatic InsP3 receptors. (Marchant JS, Chang YT, Chung SK, Irvine RF, Taylor CW) Biochem J 1997 Feb 01;321 ( Pt 3):573-6 PMID: 9032438 PMCID: PMC1218107 02/01/1997
  • Inhibitory actions of GABA on rabbit urinary bladder muscle strips: mediation by potassium channels. (Ferguson DR, Marchant JS) Br J Pharmacol 1995 May;115(1):81-3 PMID: 7647988 PMCID: PMC1908745 05/01/1995
  • Last update: 04/11/2018
    jenkins-FCD Prod-211 5bca05f6c8245a68f569aca4ee7fca9024d0e956