Medical College of Wisconsin
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Jonathan S. Marchant PhD

Jonathan S. Marchant PhD

Chair, Professor

Institution: Medical College of Wisconsin
Department: Cell Biology, Neurobiology and Anatomy
Program: Administration

Member of the Genomic Sciences and Precision Medicine Center (GSPMC)


Research Experience

  • Anthelmintics
  • Calcium
  • Calcium Channels
  • Calcium Signaling
  • Endoplasmic Reticulum
  • Inositol 1,4,5-Trisphosphate Receptors
  • Lysosomes
  • Microscopy, Confocal
  • Planarians
  • Receptors, G-Protein-Coupled
  • Regeneration
  • Schistosomiasis
  • Signal Transduction
  • Publications (96)

  • TMEM33 regulates intracellular calcium homeostasis in renal tubular epithelial cells. (Arhatte M, Gunaratne GS, El Boustany C, Kuo IY, Moro C, Duprat F, Plaisant M, Duval H, Li D, Picard N, Couvreux A, Duranton C, Rubera I, Pagnotta S, Lacas-Gervais S, Ehrlich BE, Marchant JS, Savage AM, van Eeden FJM, Wilkinson RN, Demolombe S, Honoré E, Patel A) Nat Commun 2019 05 02;10(1):2024 PMID: 31048699 PMCID: PMC6497644 SCOPUS ID: 2-s2.0-85065183745 05/03/2019    
  • Probing Ca release mechanisms using sea urchin egg homogenates. (Yuan Y, Gunaratne GS, Marchant JS, Patel S) Methods Cell Biol 2019;151:445-458 PMID: 30948025 SCOPUS ID: 2-s2.0-85061704699 04/06/2019    
  • MicroRNA-103a regulates sodium-dependent vitamin C transporter-1 expression in intestinal epithelial cells. (Subramanian VS, Sabui S, Marchant JS, Said HM) J Nutr Biochem 2019 Mar;65:46-53 PMID: 30616065 PMCID: PMC6420349 SCOPUS ID: 2-s2.0-85059472038 01/08/2019    
  • Enterotoxigenic Escherichia coli heat labile enterotoxin inhibits intestinal ascorbic acid uptake via a cAMP-dependent NF-κB-mediated pathway. (Subramenium GA, Sabui S, Marchant JS, Said HM, Subramanian VS) Am J Physiol Gastrointest Liver Physiol 2019 Jan 01;316(1):G55-G63 PMID: 30561232 SCOPUS ID: 2-s2.0-85058765526 12/19/2018       1 Citation
  • 5-Azido-8-ethynyl-NAADP: A bifunctional, clickable photoaffinity probe for the identification of NAADP receptors. (Gunaratne GS, Su P, Marchant JS, Slama JT, Walseth TF) Biochim Biophys Acta Mol Cell Res 2019 Jul;1866(7):1180-1188 PMID: 30521871 SCOPUS ID: 2-s2.0-85057588907 12/07/2018       3 Citations
  • Structure-activity profiling of alkaloid natural product pharmacophores against a Schistosoma serotonin receptor. (Marchant JS, Harding WW, Chan JD) Int J Parasitol Drugs Drug Resist 2018 12;8(3):550-558 PMID: 30297303 PMCID: PMC6287472 SCOPUS ID: 2-s2.0-85054495610 10/10/2018       4 Citations
  • Enterotoxigenic Escherichia coli heat labile enterotoxin inhibits intestinal ascorbic acid uptake via a cAMP-dependent NF-κB-mediated pathway. (Subramenium GA, Sabui S, Marchant JS, Said HM, Subramanian VS) Am J Physiol Gastrointest Liver Physiol 2019 Jan 01;316(1):G55-G63 PMID: 30285481 10/05/2018    
  • A screening campaign in sea urchin egg homogenate as a platform for discovering modulators of NAADP-dependent Ca signaling in human cells. (Gunaratne GS, Johns ME, Hintz HM, Walseth TF, Marchant JS) Cell Calcium 2018 11;75:42-52 PMID: 30145428 PMCID: PMC6286156 SCOPUS ID: 2-s2.0-85051976642 08/27/2018       4 Citations
  • NAADP-dependent Ca signaling regulates Middle East respiratory syndrome-coronavirus pseudovirus translocation through the endolysosomal system. (Gunaratne GS, Yang Y, Li F, Walseth TF, Marchant JS) Cell Calcium 2018 11;75:30-41 PMID: 30121440 PMCID: PMC6251489 SCOPUS ID: 2-s2.0-85051524070 08/20/2018       7 Citations
  • Coalescing beneficial host and deleterious antiparasitic actions as an antischistosomal strategy. (Chan JD, Day TA, Marchant JS) Elife 2018 07 30;7 PMID: 30059006 PMCID: PMC6095690 SCOPUS ID: 2-s2.0-85052114714 07/31/2018    
  • Activation of host transient receptor potential (TRP) channels by praziquantel stereoisomers. (Gunaratne GS, Yahya NA, Dosa PI, Marchant JS) PLoS Negl Trop Dis 2018 04;12(4):e0006420 PMID: 29668703 PMCID: PMC5927461 SCOPUS ID: 2-s2.0-85046410603 04/19/2018       5 Citations
  • Tumor necrosis factor alpha reduces intestinal vitamin C uptake: a role for NF-κB-mediated signaling. (Subramanian VS, Sabui S, Subramenium GA, Marchant JS, Said HM) Am J Physiol Gastrointest Liver Physiol 2018 08 01;315(2):G241-G248 PMID: 29631379 PMCID: PMC6139644 SCOPUS ID: 2-s2.0-85051254868 04/11/2018       4 Citations
  • Unique pharmacological properties of serotoninergic G-protein coupled receptors from cestodes. (Camicia F, Celentano AM, Johns ME, Chan JD, Maldonado L, Vaca H, Di Siervi N, Kamentezky L, Gamo AM, Ortega-Gutierrez S, Martin-Fontecha M, Davio C, Marchant JS, Rosenzvit MC) PLoS Negl Trop Dis 2018 02;12(2):e0006267 PMID: 29425245 PMCID: PMC5823469 SCOPUS ID: 2-s2.0-85044350844 02/10/2018       5 Citations
  • The anthelmintic praziquantel is a human serotoninergic G-protein-coupled receptor ligand. (Chan JD, Cupit PM, Gunaratne GS, McCorvy JD, Yang Y, Stoltz K, Webb TR, Dosa PI, Roth BL, Abagyan R, Cunningham C, Marchant JS) Nat Commun 2017 12 05;8(1):1910 PMID: 29208933 PMCID: PMC5716991 SCOPUS ID: 2-s2.0-85037138864 12/07/2017       22 Citations
  • Heterologous Protein Expression in the Oocyte. (Marchant JS) Cold Spring Harb Protoc 2018 04 02;2018(4) PMID: 29208643 PMCID: PMC6139252 SCOPUS ID: 2-s2.0-85044950019 12/07/2017    
  • Inhibition of intestinal ascorbic acid uptake by lipopolysaccharide is mediated via transcriptional mechanisms. (Subramanian VS, Sabui S, Moradi H, Marchant JS, Said HM) Biochim Biophys Acta Biomembr 2018 Feb;1860(2):556-565 PMID: 29030247 PMCID: PMC5732882 SCOPUS ID: 2-s2.0-85034947878 10/17/2017       7 Citations
  • Molecular mechanism(s) involved in differential expression of vitamin C transporters along the intestinal tract. (Subramanian VS, Srinivasan P, Wildman AJ, Marchant JS, Said HM) Am J Physiol Gastrointest Liver Physiol 2017 Apr 01;312(4):G340-G347 PMID: 27932501 PMCID: PMC5407060 SCOPUS ID: 2-s2.0-85016973750 12/10/2016       6 Citations
  • Dataset for a de novo transcriptome assembly, utilized for defining the voltage-gated like ion channel superfamily. (Chan JD, Zhang D, Liu X, Zarowiecki MZ, Berriman M, Marchant JS) Data Brief 2016 Dec;9:1044-1047 PMID: 27909700 PMCID: PMC5124351 12/03/2016    
  • Utilizing the planarian voltage-gated ion channel transcriptome to resolve a role for a Ca channel in neuromuscular function and regeneration. (Chan JD, Zhang D, Liu X, Zarowiecki M, Berriman M, Marchant JS) Biochim Biophys Acta Mol Cell Res 2017 Jun;1864(6):1036-1045 PMID: 27771293 PMCID: PMC5397384 SCOPUS ID: 2-s2.0-85005846711 10/25/2016       4 Citations
  • Kinetic profiling an abundantly expressed planarian serotonergic GPCR identifies bromocriptine as a perdurant antagonist. (Chan JD, Grab T, Marchant JS) Int J Parasitol Drugs Drug Resist 2016 12;6(3):356-363 PMID: 27397764 PMCID: PMC5196488 SCOPUS ID: 2-s2.0-85003481158 07/12/2016       9 Citations
  • Pharmacological profiling an abundantly expressed schistosome serotonergic GPCR identifies nuciferine as a potent antagonist. (Chan JD, Acharya S, Day TA, Marchant JS) Int J Parasitol Drugs Drug Resist 2016 12;6(3):364-370 PMID: 27397763 PMCID: PMC5196489 SCOPUS ID: 2-s2.0-84979715902 07/12/2016       10 Citations
  • A Miniaturized Screen of a Schistosoma mansoni Serotonergic G Protein-Coupled Receptor Identifies Novel Classes of Parasite-Selective Inhibitors. (Chan JD, McCorvy JD, Acharya S, Johns ME, Day TA, Roth BL, Marchant JS) PLoS Pathog 2016 05;12(5):e1005651 PMID: 27187180 PMCID: PMC4871480 SCOPUS ID: 2-s2.0-84973334825 05/18/2016       16 Citations
  • Ergot Alkaloids (Re)generate New Leads as Antiparasitics. (Chan JD, Agbedanu PN, Grab T, Zamanian M, Dosa PI, Day TA, Marchant JS) PLoS Negl Trop Dis 2015;9(9):e0004063 PMID: 26367744 PMCID: PMC4569474 SCOPUS ID: 2-s2.0-84943179139 09/15/2015       11 Citations
  • Two-pore channels at the intersection of endolysosomal membrane traffic. (Marchant JS, Patel S) Biochem Soc Trans 2015 Jun;43(3):434-41 PMID: 26009187 PMCID: PMC4730950 SCOPUS ID: 2-s2.0-84924052066 05/27/2015       18 Citations
  • TPC1 Knockout Knocks Out TPC1. (Hooper R, Churamani D, Davidson SM, Lin-Moshier Y, Walseth TF, Patel S, Marchant JS) Mol Cell Biol 2015 May;35(10):1882-3 PMID: 25900974 PMCID: PMC4405651 SCOPUS ID: 2-s2.0-84929150043 04/23/2015       4 Citations
  • Modulation of elementary calcium release mediates a transition from puffs to waves in an IP3R cluster model. (Rückl M, Parker I, Marchant JS, Nagaiah C, Johenning FW, Rüdiger S) PLoS Comput Biol 2015 Jan;11(1):e1003965 PMID: 25569772 PMCID: PMC4288706 SCOPUS ID: 2-s2.0-84922253147 01/09/2015       18 Citations
  • Dysregulation of lysosomal morphology by pathogenic LRRK2 is corrected by TPC2 inhibition. (Hockey LN, Kilpatrick BS, Eden ER, Lin-Moshier Y, Brailoiu GC, Brailoiu E, Futter CE, Schapira AH, Marchant JS, Patel S) J Cell Sci 2015 Jan 15;128(2):232-8 PMID: 25416817 PMCID: PMC4294771 SCOPUS ID: 2-s2.0-84921415558 11/25/2014       60 Citations
  • The Two-pore channel (TPC) interactome unmasks isoform-specific roles for TPCs in endolysosomal morphology and cell pigmentation. (Lin-Moshier Y, Keebler MV, Hooper R, Boulware MJ, Liu X, Churamani D, Abood ME, Walseth TF, Brailoiu E, Patel S, Marchant JS) Proc Natl Acad Sci U S A 2014 Sep 09;111(36):13087-92 PMID: 25157141 PMCID: PMC4246952 SCOPUS ID: 2-s2.0-84907001175 08/27/2014       46 Citations
  • Making heads or tails: planarian stem cells in the classroom. (Srougi MC, Thomas-Swanik J, Chan JD, Marchant JS, Carson S) J Microbiol Biol Educ 2014 May;15(1):18-25 PMID: 24839511 PMCID: PMC4004734 05/20/2014    
  • Questioning regulation of two-pore channels by NAADP. (Marchant JS, Patel S) Messenger (Los Angel) 2013 Jun 01;2(2):113-119 PMID: 24829847 PMCID: PMC4018199 05/16/2014    
  • 'Death and axes': unexpected Ca²⁺ entry phenologs predict new anti-schistosomal agents. (Chan JD, Agbedanu PN, Zamanian M, Gruba SM, Haynes CL, Day TA, Marchant JS) PLoS Pathog 2014 Feb;10(2):e1003942 PMID: 24586156 PMCID: PMC3930560 SCOPUS ID: 2-s2.0-84895771129 03/04/2014       21 Citations
  • Mitochondrial uptake of thiamin pyrophosphate: physiological and cell biological aspects. (Subramanian VS, Nabokina SM, Lin-Moshier Y, Marchant JS, Said HM) PLoS One 2013;8(8):e73503 PMID: 24023687 PMCID: PMC3758298 SCOPUS ID: 2-s2.0-84883368559 09/12/2013       15 Citations
  • Glyoxalate reductase/hydroxypyruvate reductase interacts with the sodium-dependent vitamin C transporter-1 to regulate cellular vitamin C homeostasis. (Subramanian VS, Nabokina SM, Patton JR, Marchant JS, Moradi H, Said HM) Am J Physiol Gastrointest Liver Physiol 2013 Jun 15;304(12):G1079-86 PMID: 23599041 PMCID: PMC3680717 SCOPUS ID: 2-s2.0-84879147148 04/20/2013       5 Citations
  • Characterization of a flatworm inositol (1,4,5) trisphosphate receptor (IP₃R) reveals a role in reproductive physiology. (Zhang D, Liu X, Chan JD, Marchant JS) Cell Calcium 2013 May-Jun;53(5-6):307-14 PMID: 23481272 PMCID: PMC3665645 SCOPUS ID: 2-s2.0-84891508156 03/14/2013    
  • A rapid Western blotting protocol for the Xenopus oocyte. (Lin-Moshier Y, Marchant JS) Cold Spring Harb Protoc 2013 Mar 01;2013(3) PMID: 23457341 PMCID: PMC4017335 SCOPUS ID: 2-s2.0-84874750701 03/05/2013       9 Citations
  • Nuclear microinjection to assess how heterologously expressed proteins impact Ca2+ signals in Xenopus oocytes. (Lin-Moshier Y, Marchant JS) Cold Spring Harb Protoc 2013 Mar 01;2013(3) PMID: 23457340 PMCID: PMC4021487 SCOPUS ID: 2-s2.0-84874687582 03/05/2013       5 Citations
  • The Xenopus oocyte: a single-cell model for studying Ca2+ signaling. (Lin-Moshier Y, Marchant JS) Cold Spring Harb Protoc 2013 Mar 01;2013(3) PMID: 23457336 PMCID: PMC4017334 SCOPUS ID: 2-s2.0-84874704380 03/05/2013       9 Citations
  • Ca²⁺ channels and praziquantel: a view from the free world. (Chan JD, Zarowiecki M, Marchant JS) Parasitol Int 2013 Dec;62(6):619-28 PMID: 23246536 PMCID: PMC3610807 SCOPUS ID: 2-s2.0-84885379777 12/19/2012       18 Citations
  • Re-evaluation of the role of calcium homeostasis endoplasmic reticulum protein (CHERP) in cellular calcium signaling. (Lin-Moshier Y, Sebastian PJ, Higgins L, Sampson ND, Hewitt JE, Marchant JS) J Biol Chem 2013 Jan 04;288(1):355-67 PMID: 23148228 PMCID: PMC3537033 SCOPUS ID: 2-s2.0-84872057373 11/14/2012       51 Citations
  • Modulation of function of sodium-dependent vitamin C transporter 1 (SVCT1) by Rab8a in intestinal epithelial cells: studies utilizing Caco-2 cells and Rab8a knockout mice. (Subramanian VS, Subramanya SB, Ghosal A, Marchant JS, Harada A, Said HM) Dig Dis Sci 2013 Mar;58(3):641-9 PMID: 23014846 PMCID: PMC3547156 SCOPUS ID: 2-s2.0-84876673386 09/28/2012       6 Citations
  • The Molecular Basis for Ca Signalling by NAADP: Two-Pore Channels in a Complex? (Marchant JS, Lin-Moshier Y, Walseth TF, Patel S) Messenger (Los Angel) 2012 Jun 01;1(1):63-76 PMID: 25309835 PMCID: PMC4193953 06/01/2012    
  • Nicotinic Acid Adenine Dinucleotide 2'-Phosphate (NAADP) Binding Proteins in T-Lymphocytes. (Walseth TF, Lin-Moshier Y, Weber K, Marchant JS, Slama JT, Guse AH) Messenger (Los Angel) 2012 Jun 01;1(1):86-94 PMID: 24829846 PMCID: PMC4017354 06/01/2012    
  • Photoaffinity labeling of high affinity nicotinic acid adenine dinucleotide phosphate (NAADP)-binding proteins in sea urchin egg. (Walseth TF, Lin-Moshier Y, Jain P, Ruas M, Parrington J, Galione A, Marchant JS, Slama JT) J Biol Chem 2012 Jan 20;287(4):2308-15 PMID: 22117077 PMCID: PMC3268392 SCOPUS ID: 2-s2.0-84856075676 11/26/2011       69 Citations
  • Photoaffinity labeling of nicotinic acid adenine dinucleotide phosphate (NAADP) targets in mammalian cells. (Lin-Moshier Y, Walseth TF, Churamani D, Davidson SM, Slama JT, Hooper R, Brailoiu E, Patel S, Marchant JS) J Biol Chem 2012 Jan 20;287(4):2296-307 PMID: 22117075 PMCID: PMC3268391 SCOPUS ID: 2-s2.0-84856068326 11/26/2011       97 Citations
  • Opposing roles of voltage-gated Ca2+ channels in neuronal control of regenerative patterning. (Zhang D, Chan JD, Nogi T, Marchant JS) J Neurosci 2011 Nov 02;31(44):15983-95 PMID: 22049441 PMCID: PMC3380623 SCOPUS ID: 2-s2.0-80155134773 11/04/2011       25 Citations
  • Pharmacological and functional genetic assays to manipulate regeneration of the planarian Dugesia japonica. (Chan JD, Marchant JS) J Vis Exp 2011 Aug 31(54) PMID: 21897362 PMCID: PMC3217636 SCOPUS ID: 2-s2.0-84859909945 09/08/2011       7 Citations
  • Differential expression of human riboflavin transporters -1, -2, and -3 in polarized epithelia: a key role for hRFT-2 in intestinal riboflavin uptake. (Subramanian VS, Subramanya SB, Rapp L, Marchant JS, Ma TY, Said HM) Biochim Biophys Acta 2011 Dec;1808(12):3016-21 PMID: 21854757 PMCID: PMC3196270 SCOPUS ID: 2-s2.0-80054773593 08/23/2011       37 Citations
  • The endo-lysosomal system as an NAADP-sensitive acidic Ca(2+) store: role for the two-pore channels. (Patel S, Ramakrishnan L, Rahman T, Hamdoun A, Marchant JS, Taylor CW, Brailoiu E) Cell Calcium 2011 Aug;50(2):157-67 PMID: 21529939 PMCID: PMC3160778 05/03/2011    
  • Role of cysteine residues in cell surface expression of the human riboflavin transporter-2 (hRFT2) in intestinal epithelial cells. (Subramanian VS, Rapp L, Marchant JS, Said HM) Am J Physiol Gastrointest Liver Physiol 2011 Jul;301(1):G100-9 PMID: 21512156 PMCID: PMC3129935 SCOPUS ID: 2-s2.0-79959842140 04/23/2011       23 Citations
  • Inositol (1,4,5)-trisphosphate receptor microarchitecture shapes Ca2+ puff kinetics. (Diambra L, Marchant JS) Biophys J 2011 Feb 16;100(4):822-31 PMID: 21320425 PMCID: PMC3037600 02/16/2011    
  • Two-pore channels: Regulation by NAADP and customized roles in triggering calcium signals. (Patel S, Marchant JS, Brailoiu E) Cell Calcium 2010 Jun;47(6):480-90 PMID: 20621760 PMCID: PMC2921607 SCOPUS ID: 2-s2.0-77953916412 07/14/2010       64 Citations
  • An ancestral deuterostome family of two-pore channels mediates nicotinic acid adenine dinucleotide phosphate-dependent calcium release from acidic organelles. (Brailoiu E, Hooper R, Cai X, Brailoiu GC, Keebler MV, Dun NJ, Marchant JS, Patel S) J Biol Chem 2010 Jan 29;285(5):2897-901 PMID: 19940116 PMCID: PMC2823445 SCOPUS ID: 2-s2.0-77449093874 11/27/2009       77 Citations
  • Molecular determinants dictating cell surface expression of the human sodium-dependent vitamin C transporter-2 in human liver cells. (Subramanian VS, Marchant JS, Said HM) Am J Physiol Gastrointest Liver Physiol 2010 Feb;298(2):G267-74 PMID: 19926816 PMCID: PMC2822508 SCOPUS ID: 2-s2.0-76749113011 11/21/2009       9 Citations
  • Localization and socialization: experimental insights into the functional architecture of IP3 receptors. (Diambra L, Marchant JS) Chaos 2009 Sep;19(3):037103 PMID: 19792028 PMCID: PMC2771704 SCOPUS ID: 2-s2.0-70349634912 10/02/2009       13 Citations
  • Essential requirement for two-pore channel 1 in NAADP-mediated calcium signaling. (Brailoiu E, Churamani D, Cai X, Schrlau MG, Brailoiu GC, Gao X, Hooper R, Boulware MJ, Dun NJ, Marchant JS, Patel S) J Cell Biol 2009 Jul 27;186(2):201-9 PMID: 19620632 PMCID: PMC2717647 SCOPUS ID: 2-s2.0-67749143745 07/22/2009       243 Citations
  • Dual mechanisms of sHA 14-1 in inducing cell death through endoplasmic reticulum and mitochondria. (Hermanson D, Addo SN, Bajer AA, Marchant JS, Das SG, Srinivasan B, Al-Mousa F, Michelangeli F, Thomas DD, Lebien TW, Xing C) Mol Pharmacol 2009 Sep;76(3):667-78 PMID: 19561125 PMCID: PMC2730395 SCOPUS ID: 2-s2.0-69549124714 06/30/2009       36 Citations
  • A novel biological activity of praziquantel requiring voltage-operated Ca2+ channel beta subunits: subversion of flatworm regenerative polarity. (Nogi T, Zhang D, Chan JD, Marchant JS) PLoS Negl Trop Dis 2009 Jun 23;3(6):e464 PMID: 19554083 PMCID: PMC2694594 SCOPUS ID: 2-s2.0-68349085863 06/26/2009       70 Citations
  • Membrane targeting and intracellular trafficking of the human sodium-dependent multivitamin transporter in polarized epithelial cells. (Subramanian VS, Marchant JS, Boulware MJ, Ma TY, Said HM) Am J Physiol Cell Physiol 2009 Apr;296(4):C663-71 PMID: 19211916 PMCID: PMC2670647 SCOPUS ID: 2-s2.0-65649091395 02/13/2009       24 Citations
  • Molecular characterization of a novel cell surface ADP-ribosyl cyclase from the sea urchin. (Churamani D, Boulware MJ, Ramakrishnan L, Geach TJ, Martin AC, Vacquier VD, Marchant JS, Dale L, Patel S) Cell Signal 2008 Dec;20(12):2347-55 PMID: 18824228 PMCID: PMC4313535 SCOPUS ID: 2-s2.0-55049128821 10/01/2008       11 Citations
  • Timing in cellular Ca2+ signaling. (Boulware MJ, Marchant JS) Curr Biol 2008 Sep 09;18(17):R769-R776 PMID: 18786382 PMCID: PMC3236564 SCOPUS ID: 2-s2.0-50849084152 09/13/2008       31 Citations
  • N-Glycosylation is required for Na+-dependent vitamin C transporter functionality. (Subramanian VS, Marchant JS, Reidling JC, Said HM) Biochem Biophys Res Commun 2008 Sep 12;374(1):123-7 PMID: 18619416 PMCID: PMC2528843 SCOPUS ID: 2-s2.0-47749122550 07/16/2008       32 Citations
  • Nuclear pore disassembly from endoplasmic reticulum membranes promotes Ca2+ signalling competency. (Boulware MJ, Marchant JS) J Physiol 2008 Jun 15;586(12):2873-88 PMID: 18450775 PMCID: PMC2517208 SCOPUS ID: 2-s2.0-45249108917 05/03/2008       15 Citations
  • Enhanced Ca2+ leak from ER Ca2+ stores induced by hepatitis C NS5A protein. (Robinson LC, Marchant JS) Biochem Biophys Res Commun 2008 Apr 11;368(3):593-9 PMID: 18258181 PMCID: PMC2292798 SCOPUS ID: 2-s2.0-39749118497 02/09/2008       17 Citations
  • Apical membrane targeting and trafficking of the human proton-coupled transporter in polarized epithelia. (Subramanian VS, Marchant JS, Said HM) Am J Physiol Cell Physiol 2008 Jan;294(1):C233-40 PMID: 18003745 SCOPUS ID: 2-s2.0-38349097299 11/16/2007       34 Citations
  • Tight junction targeting and intracellular trafficking of occludin in polarized epithelial cells. (Subramanian VS, Marchant JS, Ye D, Ma TY, Said HM) Am J Physiol Cell Physiol 2007 Nov;293(5):C1717-26 PMID: 17855770 SCOPUS ID: 2-s2.0-36049047582 09/15/2007       23 Citations
  • Molecular characterization of a novel intracellular ADP-ribosyl cyclase. (Churamani D, Boulware MJ, Geach TJ, Martin AC, Moy GW, Su YH, Vacquier VD, Marchant JS, Dale L, Patel S) PLoS One 2007 Aug 29;2(8):e797 PMID: 17726527 PMCID: PMC1949048 SCOPUS ID: 2-s2.0-40749129606 08/30/2007       26 Citations
  • Vitamin B1 (thiamine) uptake by human retinal pigment epithelial (ARPE-19) cells: mechanism and regulation. (Subramanian VS, Mohammed ZM, Molina A, Marchant JS, Vaziri ND, Said HM) J Physiol 2007 Jul 01;582(Pt 1):73-85 PMID: 17463047 PMCID: PMC2075275 SCOPUS ID: 2-s2.0-34347236918 04/28/2007       21 Citations
  • The inositol 1,4,5-trisphosphate receptor (Itpr) gene family in Xenopus: identification of type 2 and type 3 inositol 1,4,5-trisphosphate receptor subtypes. (Zhang D, Boulware MJ, Pendleton MR, Nogi T, Marchant JS) Biochem J 2007 Jun 15;404(3):383-91 PMID: 17338679 PMCID: PMC1896291 SCOPUS ID: 2-s2.0-34250782108 03/07/2007       10 Citations
  • Targeting and intracellular trafficking of clinically relevant hTHTR1 mutations in human cell lines. (Subramanian VS, Marchant JS, Said HM) Clin Sci (Lond) 2007 Jul;113(2):93-102 PMID: 17331069 SCOPUS ID: 2-s2.0-34447512789 03/03/2007       12 Citations
  • Calcium influx: beyond 'current' biology. (Robinson LC, Marchant JS) Curr Biol 2006 Jul 25;16(14):R548-50 PMID: 16860734 SCOPUS ID: 2-s2.0-33746023323 07/25/2006       2 Citations
  • Biotin-responsive basal ganglia disease-linked mutations inhibit thiamine transport via hTHTR2: biotin is not a substrate for hTHTR2. (Subramanian VS, Marchant JS, Said HM) Am J Physiol Cell Physiol 2006 Nov;291(5):C851-9 PMID: 16790503 SCOPUS ID: 2-s2.0-33751091272 06/23/2006       49 Citations
  • Targeting and trafficking of the human thiamine transporter-2 in epithelial cells. (Subramanian VS, Marchant JS, Said HM) J Biol Chem 2006 Feb 24;281(8):5233-45 PMID: 16371350 SCOPUS ID: 2-s2.0-33646185694 12/24/2005       26 Citations
  • Cellular signalling: STIMulating calcium entry. (Marchant JS) Curr Biol 2005 Jul 12;15(13):R493-5 PMID: 16005278 SCOPUS ID: 2-s2.0-21844432949 07/12/2005       14 Citations
  • IP3 receptor activity is differentially regulated in endoplasmic reticulum subdomains during oocyte maturation. (Boulware MJ, Marchant JS) Curr Biol 2005 Apr 26;15(8):765-70 PMID: 15854911 SCOPUS ID: 2-s2.0-18044379030 04/28/2005       37 Citations
  • Improved "optical highlighter" probes derived from discosoma red fluorescent protein. (Robinson LC, Marchant JS) Biophys J 2005 Feb;88(2):1444-57 PMID: 15556986 PMCID: PMC1305146 SCOPUS ID: 2-s2.0-21244452684 11/24/2004       10 Citations
  • Calcium-dependent dephosphorylation mediates the hyperosmotic and lysophosphatidic acid-dependent inhibition of natriuretic peptide receptor-B/guanylyl cyclase-B. (Potthast R, Abbey-Hosch SE, Antos LK, Marchant JS, Kuhn M, Potter LR) J Biol Chem 2004 Nov 19;279(47):48513-9 PMID: 15371450 SCOPUS ID: 2-s2.0-10344265038 09/17/2004       29 Citations
  • A C-terminal region dictates the apical plasma membrane targeting of the human sodium-dependent vitamin C transporter-1 in polarized epithelia. (Subramanian VS, Marchant JS, Boulware MJ, Said HM) J Biol Chem 2004 Jun 25;279(26):27719-28 PMID: 15084584 SCOPUS ID: 2-s2.0-3042637491 04/16/2004       55 Citations
  • Expression and functional contribution of hTHTR-2 in thiamin absorption in human intestine. (Said HM, Balamurugan K, Subramanian VS, Marchant JS) Am J Physiol Gastrointest Liver Physiol 2004 Mar;286(3):G491-8 PMID: 14615284 SCOPUS ID: 2-s2.0-1342344122 11/15/2003       77 Citations
  • Polarized expression of members of the solute carrier SLC19A gene family of water-soluble multivitamin transporters: implications for physiological function. (Boulware MJ, Subramanian VS, Said HM, Marchant JS) Biochem J 2003 Nov 15;376(Pt 1):43-8 PMID: 14602044 PMCID: PMC1223768 SCOPUS ID: 2-s2.0-0344825276 11/07/2003       31 Citations
  • Cell biology of the human thiamine transporter-1 (hTHTR1). Intracellular trafficking and membrane targeting mechanisms. (Subramanian VS, Marchant JS, Parker I, Said HM) J Biol Chem 2003 Feb 07;278(6):3976-84 PMID: 12454006 SCOPUS ID: 2-s2.0-0037423188 11/28/2002       51 Citations
  • Intracellular trafficking and membrane targeting mechanisms of the human reduced folate carrier in Mammalian epithelial cells. (Marchant JS, Subramanian VS, Parker I, Said HM) J Biol Chem 2002 Sep 06;277(36):33325-33 PMID: 12087110 SCOPUS ID: 2-s2.0-0037031857 06/28/2002       34 Citations
  • Structural and functional relationships between Ca2+ puffs and mitochondria in Xenopus oocytes. (Marchant JS, Ramos V, Parker I) Am J Physiol Cell Physiol 2002 Jun;282(6):C1374-86 PMID: 11997252 SCOPUS ID: 2-s2.0-0036087280 05/09/2002       38 Citations
  • Intracellular trafficking/membrane targeting of human reduced folate carrier expressed in Xenopus oocytes. (Subramanian VS, Marchant JS, Parker I, Said HM) Am J Physiol Gastrointest Liver Physiol 2001 Dec;281(6):G1477-86 PMID: 11705753 SCOPUS ID: 2-s2.0-0035662165 11/14/2001       26 Citations
  • Multiphoton-evoked color change of DsRed as an optical highlighter for cellular and subcellular labeling. (Marchant JS, Stutzmann GE, Leissring MA, LaFerla FM, Parker I) Nat Biotechnol 2001 Jul;19(7):645-9 PMID: 11433276 SCOPUS ID: 2-s2.0-0034930509 07/04/2001       87 Citations
  • Xenopus tropicalis oocytes as an advantageous model system for the study of intracellular Ca(2+) signalling. (Marchant JS, Parker I) Br J Pharmacol 2001 Apr;132(7):1396-410 PMID: 11264232 PMCID: PMC1572681 03/27/2001    
  • Role of elementary Ca(2+) puffs in generating repetitive Ca(2+) oscillations. (Marchant JS, Parker I) EMBO J 2001 Jan 15;20(1-2):65-76 PMID: 11226156 PMCID: PMC140189 SCOPUS ID: 2-s2.0-0035863066 02/28/2001       154 Citations
  • Functional interactions in Ca(2+) signaling over different time and distance scales. (Marchant JS, Parker I) J Gen Physiol 2000 Nov;116(5):691-6 PMID: 11055997 PMCID: PMC2229487 SCOPUS ID: 2-s2.0-0033761765 10/31/2000       17 Citations
  • Acyclophostin: a ribose-modified analog of adenophostin A with high affinity for inositol 1,4,5-trisphosphate receptors and pH-dependent efficacy. (Beecroft MD, Marchant JS, Riley AM, Van Straten NC, Van der Marel GA, Van Boom JH, Potter BV, Taylor CW) Mol Pharmacol 1999 Jan;55(1):109-17 PMID: 9882704 SCOPUS ID: 2-s2.0-0032953886 01/12/1999       28 Citations
  • Kinetics of elementary Ca2+ puffs evoked in Xenopus oocytes by different Ins(1,4,5)P3 receptor agonists. (Marchant JS, Parker I) Biochem J 1998 Sep 15;334 ( Pt 3):505-9 PMID: 9729454 PMCID: PMC1219715 SCOPUS ID: 2-s2.0-0032530345 09/08/1998       21 Citations
  • Rapid activation and partial inactivation of inositol trisphosphate receptors by inositol trisphosphate. (Marchant JS, Taylor CW) Biochemistry 1998 Aug 18;37(33):11524-33 PMID: 9708988 SCOPUS ID: 2-s2.0-0032544178 08/26/1998       52 Citations
  • Activation and co-ordination of InsP3-mediated elementary Ca2+ events during global Ca2+ signals in Xenopus oocytes. (Callamaras N, Marchant JS, Sun XP, Parker I) J Physiol 1998 May 15;509 ( Pt 1):81-91 PMID: 9547383 PMCID: PMC2230929 SCOPUS ID: 2-s2.0-0032523864 06/17/1998       130 Citations
  • A continuum of InsP3-mediated elementary Ca2+ signalling events in Xenopus oocytes. (Sun XP, Callamaras N, Marchant JS, Parker I) J Physiol 1998 May 15;509 ( Pt 1):67-80 PMID: 9547382 PMCID: PMC2230949 SCOPUS ID: 2-s2.0-0032523987 06/17/1998       208 Citations
  • Disaccharide polyphosphates based upon adenophostin A activate hepatic D-myo-inositol 1,4,5-trisphosphate receptors. (Marchant JS, Beecroft MD, Riley AM, Jenkins DJ, Marwood RD, Taylor CW, Potter BV) Biochemistry 1997 Oct 21;36(42):12780-90 PMID: 9335535 SCOPUS ID: 2-s2.0-0030722963 10/23/1997       62 Citations
  • Cooperative activation of IP3 receptors by sequential binding of IP3 and Ca2+ safeguards against spontaneous activity. (Marchant JS, Taylor CW) Curr Biol 1997 Jul 01;7(7):510-8 PMID: 9210378 SCOPUS ID: 2-s2.0-0030610150 07/01/1997       119 Citations
  • Rapid kinetic measurements of 45Ca2+ mobilization reveal that Ins(2,4,5)P3 is a partial agonist at hepatic InsP3 receptors. (Marchant JS, Chang YT, Chung SK, Irvine RF, Taylor CW) Biochem J 1997 Feb 01;321 ( Pt 3):573-6 PMID: 9032438 PMCID: PMC1218107 SCOPUS ID: 2-s2.0-0031050705 02/01/1997       34 Citations
  • Inhibitory actions of GABA on rabbit urinary bladder muscle strips: mediation by potassium channels. (Ferguson DR, Marchant JS) Br J Pharmacol 1995 May;115(1):81-3 PMID: 7647988 PMCID: PMC1908745 SCOPUS ID: 2-s2.0-0029063427 05/01/1995       10 Citations
  • Last update: 07/05/2019
    jenkins-FCD Prod-388 89e904233d719332173309c68ab82b0b2a78a3a7