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Publications indexed to the term Vasodilation

FacultyTitle
1Endothelial TERT drives microvascular phenotype associated with coronary artery disease. (Birch EC, Nishijima Y, Hader SN, Beyer AM) Am J Physiol Heart Circ Physiol 2025 Jul 01;329(1):H267-H270    
2Prolonged L-NAME exposure changes the vasodilator factor from NO to H2O2 in human arterioles in response to A23187. (Zinkevich NS, Drachuk K, Zhang DX) Vascul Pharmacol 2024 Dec;157:107440    
1Dehydroepiandrosterone (DHEA), a circulating steroid hormone precursor produced potent vasorelaxation in rat aorta and mesenteric arteries through blockade of L-type voltage-dependent calcium channels. (Mishra D, Yadav P, Iqbal H, Parashar S, Negi AS, Chanda D) Microvasc Res 2025 Jan;157:104758       1 Citation
1The acute effects of dietary nitrate supplementation on postmenopausal endothelial resistance to ischemia reperfusion injury: a randomized, placebo-controlled, double blind, crossover clinical trial. (Delgado Spicuzza J, Gosalia J, Studinski M, Armando C, Alipour E, Kim-Shapiro D, Flanagan M, Somani Y, Proctor D) Can J Physiol Pharmacol 2024 Nov 01;102(11):634-647       1 Citation
1Role of the circulating milieu in age-related arterial dysfunction: a novel ex vivo approach. (Mahoney SA, VanDongen NS, Greenberg NT, Venkatasubramanian R, Rossman MJ, Widlansky ME, Brunt VE, Bernaldo de Quirós Y, Seals DR, Clayton ZS) Am J Physiol Heart Circ Physiol 2024 May 01;326(5):H1279-H1290       7 Citations
1Evidence of premature vascular dysfunction in young adults who regularly use e-cigarettes and the impact of usage length. (Matheson C, Simovic T, Heefner A, Colon M, Tunon E, Cobb K, Thode C, Breland A, Cobb CO, Nana-Sinkam P, Garten R, Rodriguez-Miguelez P) Angiogenesis 2024 May;27(2):229-243       7 Citations
15,6-diHETE lactone (EPA-L) mediates hypertensive microvascular dilation by activating the endothelial GPR-PLC-IP3 signaling pathway. (Asulin M, Gorodetzer N, Fridman R, Shelly Ben-Shushan R, Cohen Z, Beyer AM, Chuyun D, Gutterman DD, Szuchman-Sapir A) Biochem Biophys Res Commun 2024 Mar 12;700:149585       4 Citations
1Independent endothelial functions of PIEZO1 and TRPV4 in hepatic portal vein and predominance of PIEZO1 in mechanical and osmotic stress. (Endesh N, Chuntharpursat-Bon E, Revill C, Yuldasheva NY, Futers TS, Parsonage G, Humphreys N, Adamson A, Morley LC, Cubbon RM, Prasad KR, Foster R, Lichtenstein L, Beech DJ) Liver Int 2023 Sep;43(9):2026-2038       20 Citations
1Synthesis of 6-alkoxy and 6-hydroxy-alkyl amine derivatives of braylin as vasorelaxing agents. (Nainawat KS, Singh S, Agarwal K, Iqbal H, Rani P, Bhatt D, Khan S, Chanda D, Bawankule DU, Tandon S, Khan F, Kumar Gupta A, Gupta A) Bioorg Med Chem Lett 2023 Jun 01;89:129311       1 Citation
117β-Estradiol promotes sex-specific dysfunction in isolated human arterioles. (SenthilKumar G, Katunaric B, Bordas-Murphy H, Young M, Doren EL, Schulz ME, Widlansky ME, Freed JK) Am J Physiol Heart Circ Physiol 2023 Mar 01;324(3):H330-H337       17 Citations
1Lipid phosphate phosphatase 3 maintains NO-mediated flow-mediated dilatation in human adipose resistance arterioles. (Chabowski DS, Hughes WE, Hockenberry JC, LoGiudice J, Beyer AM, Gutterman DD) J Physiol 2023 Feb;601(3):469-481       5 Citations
3Noncanonical Role of Telomerase in Regulation of Microvascular Redox Environment With Implications for Coronary Artery Disease. (Ait-Aissa K, Norwood-Toro LE, Terwoord J, Young M, Paniagua LA, Hader SN, Hughes WE, Hockenberry JC, Beare JE, Linn J, Kohmoto T, Kim J, Betts DH, LeBlanc AJ, Gutterman DD, Beyer AM) Function (Oxf) 2022;3(5):zqac043       12 Citations
3Endothelial Cullin3 Mutation Impairs Nitric Oxide-Mediated Vasodilation and Promotes Salt-Induced Hypertension. (Wu J, Fang S, Lu KT, Kumar G, Reho JJ, Brozoski DT, Otanwa AJ, Hu C, Nair AR, Wackman KK, Agbor LN, Grobe JL, Sigmund CD) Function (Oxf) 2022;3(3):zqac017       13 Citations
5NADPH oxidase 4 contributes to TRPV4-mediated endothelium-dependent vasodilation in human arterioles by regulating protein phosphorylation of TRPV4 channels. (Xie Y, Nishijima Y, Zinkevich NS, Korishettar A, Fang J, Mathison AJ, Zimmermann MT, Wilcox DA, Gutterman DD, Shen Y, Zhang DX) Basic Res Cardiol 2022 Apr 25;117(1):24       11 Citations
3Prolonged endothelial-dysfunction in human arterioles following infection with SARS-CoV-2. (Nishijima Y, Hader SN, Hanson AJ, Zhang DX, Sparapani R, Gutterman DD, Beyer AM) Cardiovasc Res 2022 Jan 07;118(1):18-19       18 Citations
2Abnormal hearing patterns are not associated with endothelium-dependent vasodilation and carotid intima-media thickness: The Framingham Heart Study. (Tyagi S, Friedland DR, Rein L, Tarima SS, Mueller C, Benjamin EJ, Vasan RS, Hamburg NM, Widlansky ME) Vasc Med 2021 Dec;26(6):595-601       3 Citations
2Vascular effects of disrupting endothelial mTORC1 signaling in obesity. (Reho JJ, Guo DF, Beyer AM, Wegman-Points L, Pierce GL, Rahmouni K) Am J Physiol Regul Integr Comp Physiol 2021 Aug 01;321(2):R228-R237       6 Citations
1Red light stimulates vasodilation through extracellular vesicle trafficking. (Weihrauch D, Keszler A, Lindemer B, Krolikowski J, Lohr NL) J Photochem Photobiol B 2021 Jul;220:112212       23 Citations
2EP3 (E-Prostanoid 3) Receptor Mediates Impaired Vasodilation in a Mouse Model of Salt-Sensitive Hypertension. (Wu J, Fang S, Lu KT, Wackman K, Schwartzman ML, Dikalov SI, Grobe JL, Sigmund CD) Hypertension 2021 Apr;77(4):1399-1411       17 Citations
2Hypertension preserves the magnitude of microvascular flow-mediated dilation following transient elevation in intraluminal pressure. (Hughes WE, Zinkevich N, Gutterman DD, Beyer AM) Physiol Rep 2021 Feb;9(3):e14507       4 Citations
2Long-term oral administration of a novel estrogen receptor beta agonist enhances memory and alleviates drug-induced vasodilation in young ovariectomized mice. (Fleischer AW, Schalk JC, Wetzel EA, Hanson AM, Sem DS, Donaldson WA, Frick KM) Horm Behav 2021 Apr;130:104948       20 Citations
2Critical Interaction Between Telomerase and Autophagy in Mediating Flow-Induced Human Arteriolar Vasodilation. (Hughes WE, Chabowski DS, Ait-Aissa K, Fetterman JL, Hockenberry J, Beyer AM, Gutterman DD) Arterioscler Thromb Vasc Biol 2021 Jan;41(1):446-457       19 Citations
3Two weeks of remote ischemic conditioning improves brachial artery flow mediated dilation in chronic stroke survivors. (Hyngstrom AS, Nguyen JN, Wright MT, Tarima SS, Schmit BD, Gutterman DD, Durand MJ) J Appl Physiol (1985) 2020 Dec 01;129(6):1348-1354       15 Citations
1H2 S donor improves heart function and vascular relaxation in diabetes. (Dorofeyeva N, Drachuk K, Rajkumar R, Sabnis O, Sagach V) Eur J Clin Invest 2021 Jan;51(1):e13354       7 Citations
3Failure to vasodilate in response to salt loading blunts renal blood flow and causes salt-sensitive hypertension. (Wu J, Agbor LN, Fang S, Mukohda M, Nair AR, Nakagawa P, Sharma A, Morgan DA, Grobe JL, Rahmouni K, Weiss RM, McCormick JA, Sigmund CD) Cardiovasc Res 2021 Jan 01;117(1):308-319       25 Citations
2BCR-ABL tyrosine kinase inhibitors promote pathological changes in dilator phenotype in the human microvasculature. (Durand MJ, Hader SN, Derayunan A, Zinkevich N, McIntosh JJ, Beyer AM) Microcirculation 2020 Oct;27(7):e12625       8 Citations
1Dietary nitrate does not acutely enhance skeletal muscle blood flow and vasodilation in the lower limbs of older adults during single-limb exercise. (Hughes WE, Kruse NT, Ueda K, Feider AJ, Hanada S, Bock JM, Casey DP) Eur J Appl Physiol 2020 Jun;120(6):1357-1369       9 Citations
1Role of dopamine and selective dopamine receptor agonists on mouse ductus arteriosus tone and responsiveness. (Crockett SL, Harris M, Boatwright N, Su RL, Yarboro MT, Berger CD, Shelton EL, Reese J, Segar JL) Pediatr Res 2020 May;87(6):991-997       3 Citations
1Synthesis and evaluation of substituted 8,8-dimethyl-8H-pyrano[2,3-f]chromen-2-one derivatives as vasorelaxing agents. (Singh S, Agarwal K, Iqbal H, Yadav P, Yadav D, Chanda D, Tandon S, Khan F, Gupta AK, Gupta A) Bioorg Med Chem Lett 2020 Jan 01;30(1):126759       9 Citations
1Circulating levels of mitochondrial uncoupling protein 2, but not prohibitin, are lower in humans with type 2 diabetes and correlate with brachial artery flow-mediated dilation. (Kakarla M, Puppala VK, Tyagi S, Anger A, Repp K, Wang J, Ying R, Widlansky ME) Cardiovasc Diabetol 2019 Nov 09;18(1):148       11 Citations
1Smooth Muscle Cell-Specific Disruption of the BBSome Causes Vascular Dysfunction. (Reho JJ, Guo DF, Morgan DA, Rahmouni K) Hypertension 2019 Oct;74(4):817-825       13 Citations
1Detrimental effects of chemotherapy on human coronary microvascular function. (Hader SN, Zinkevich N, Norwood Toro LE, Kriegel AJ, Kong A, Freed JK, Gutterman DD, Beyer AM) Am J Physiol Heart Circ Physiol 2019 Oct 01;317(4):H705-H710       32 Citations
1Antihypertensive activity of diethyl-4,4'-dihydroxy-8,3'-neolign-7,7'-dien-9,9'-dionate: A continuation study in L-NAME treated wistar rats. (Singh A, Kumar BS, Iqbal H, Alam S, Yadav P, Verma AK, Khan F, Shanker K, Hanif K, Negi AS, Chanda D) Eur J Pharmacol 2019 Sep 05;858:172482       5 Citations
1Conditional deletion of smooth muscle Cullin-3 causes severe progressive hypertension. (Agbor LN, Nair AR, Wu J, Lu KT, Davis DR, Keen HL, Quelle FW, McCormick JA, Singer JD, Sigmund CD) JCI Insight 2019 Jun 11;5(14)       30 Citations
1Mechanistic Target of Rapamycin Complex 1 Signaling Modulates Vascular Endothelial Function Through Reactive Oxygen Species. (Reho JJ, Guo DF, Rahmouni K) J Am Heart Assoc 2019 May 07;8(9):e010662       29 Citations
5Human genotyping and an experimental model reveal NPR-C as a possible contributor to morbidity in coarctation of the aorta. (LaDisa JF Jr, Tomita-Mitchell A, Stamm K, Bazan K, Mahnke DK, Goetsch MA, Wegter BJ, Gerringer JW, Repp K, Palygin O, Zietara AP, Krolikowski MM, Eddinger TJ, Alli AA, Mitchell ME) Physiol Genomics 2019 Jun 01;51(6):177-185       14 Citations
1RhoBTB1 protects against hypertension and arterial stiffness by restraining phosphodiesterase 5 activity. (Mukohda M, Fang S, Wu J, Agbor LN, Nair AR, Ibeawuchi SC, Hu C, Liu X, Lu KT, Guo DF, Davis DR, Keen HL, Quelle FW, Sigmund CD) J Clin Invest 2019 Mar 21;129(6):2318-2332       38 Citations
1Marked Vascular Dysfunction in a Case of Peripartum Cardiomyopathy. (Khanamiri S, Rhee JW, Paik DT, Chen IY, Liu C, Sayed N) J Vasc Res 2019;56(1):11-15       4 Citations
1Interference With Endothelial PPAR (Peroxisome Proliferator-Activated Receptor)-γ Causes Accelerated Cerebral Vascular Dysfunction in Response to Endogenous Renin-Angiotensin System Activation. (Nair AR, Agbor LN, Mukohda M, Liu X, Hu C, Wu J, Sigmund CD) Hypertension 2018 Nov;72(5):1227-1235       20 Citations
3Lactobacillus plantarum 299v Supplementation Improves Vascular Endothelial Function and Reduces Inflammatory Biomarkers in Men With Stable Coronary Artery Disease. (Malik M, Suboc TM, Tyagi S, Salzman N, Wang J, Ying R, Tanner MJ, Kakarla M, Baker JE, Widlansky ME) Circ Res 2018 Oct 12;123(9):1091-1102       186 Citations
2Ascorbate attenuates red light mediated vasodilation: Potential role of S-nitrosothiols. (Keszler A, Lindemer B, Hogg N, Lohr NL) Redox Biol 2019 Jan;20:13-18       12 Citations
1Inactivation of p66Shc Decreases Afferent Arteriolar KATP Channel Activity and Decreases Renal Damage in Diabetic Dahl SS Rats. (Miller BS, Blumenthal SR, Shalygin A, Wright KD, Staruschenko A, Imig JD, Sorokin A) Diabetes 2018 Nov;67(11):2206-2212       14 Citations
1Inorganic nitrate supplementation enhances functional capacity and lower-limb microvascular reactivity in patients with peripheral artery disease. (Bock JM, Treichler DP, Norton SL, Ueda K, Hughes WE, Casey DP) Nitric Oxide 2018 Nov 01;80:45-51       28 Citations
1Habitual exercise training in older adults offsets the age-related prolongation in leg vasodilator kinetics during single-limb lower body exercise. (Hughes WE, Kruse NT, Ueda K, Casey DP) J Appl Physiol (1985) 2018 Sep 01;125(3):746-754       3 Citations
2Wavelength-dependence of vasodilation and NO release from S-nitrosothiols and dinitrosyl iron complexes by far red/near infrared light. (Keszler A, Lindemer B, Hogg N, Weihrauch D, Lohr NL) Arch Biochem Biophys 2018 Jul 01;649:47-52       52 Citations
1Endothelial PPARγ (Peroxisome Proliferator-Activated Receptor-γ) Is Essential for Preventing Endothelial Dysfunction With Aging. (De Silva TM, Li Y, Kinzenbaw DA, Sigmund CD, Faraci FM) Hypertension 2018 Jul;72(1):227-234       35 Citations
1Age-associated impairments in contraction-induced rapid-onset vasodilatation within the forearm are independent of mechanical factors. (Hughes WE, Kruse NT, Casey DP) Exp Physiol 2018 May 01;103(5):728-737       3 Citations
3miR-29 contributes to normal endothelial function and can restore it in cardiometabolic disorders. (Widlansky ME, Jensen DM, Wang J, Liu Y, Geurts AM, Kriegel AJ, Liu P, Ying R, Zhang G, Casati M, Chu C, Malik M, Branum A, Tanner MJ, Tyagi S, Usa K, Liang M) EMBO Mol Med 2018 Mar;10(3)       81 Citations
1The quest for endothelial atypical cannabinoid receptor: BKCa channels act as cellular sensors for cannabinoids in in vitro and in situ endothelial cells. (Bondarenko AI, Panasiuk O, Drachuk K, Montecucco F, Brandt KJ, Mach F) Vascul Pharmacol 2018 Mar;102:44-55       20 Citations
1Telomerase reverse transcriptase protects against angiotensin II-induced microvascular endothelial dysfunction. (Ait-Aissa K, Kadlec AO, Hockenberry J, Gutterman DD, Beyer AM) Am J Physiol Heart Circ Physiol 2018 May 01;314(5):H1053-H1060       31 Citations
1Signalling of vasodilatation across an exercise transient. (Hughes WE) J Physiol 2018 Feb 15;596(4):559-560       2 Citations
1Shaker-related voltage-gated K+ channel expression and vasomotor function in human coronary resistance arteries. (Nishijima Y, Korishettar A, Chabowski DS, Cao S, Zheng X, Gutterman DD, Zhang DX) Microcirculation 2018 Jan;25(1)       8 Citations
1Microvascular Adaptations to Exercise: Protective Effect of PGC-1 Alpha. (Kadlec AO, Barnes C, Durand MJ, Gutterman DD) Am J Hypertens 2018 Jan 12;31(2):240-246       8 Citations
1Obligatory Metabolism of Angiotensin II to Angiotensin III for Zona Glomerulosa Cell-Mediated Relaxations of Bovine Adrenal Cortical Arteries. (Kopf PG, Park SK, Herrnreiter A, Krause C, Roques BP, Campbell WB) Endocrinology 2018 Jan 01;159(1):238-247       4 Citations
1Orally Active Epoxyeicosatrienoic Acid Analogs. (Campbell WB, Imig JD, Schmitz JM, Falck JR) J Cardiovasc Pharmacol 2017 Oct;70(4):211-224       48 Citations
1Genetic Interference With Endothelial PPAR-γ (Peroxisome Proliferator-Activated Receptor-γ) Augments Effects of Angiotensin II While Impairing Responses to Angiotensin 1-7. (De Silva TM, Hu C, Kinzenbaw DA, Modrick ML, Sigmund CD, Faraci FM) Hypertension 2017 Sep;70(3):559-565       17 Citations
3PGC-1α (Peroxisome Proliferator-Activated Receptor γ Coactivator 1-α) Overexpression in Coronary Artery Disease Recruits NO and Hydrogen Peroxide During Flow-Mediated Dilation and Protects Against Increased Intraluminal Pressure. (Kadlec AO, Chabowski DS, Ait-Aissa K, Hockenberry JC, Otterson MF, Durand MJ, Freed JK, Beyer AM, Gutterman DD) Hypertension 2017 Jul;70(1):166-173       44 Citations
1Roles of NADPH oxidase and mitochondria in flow-induced vasodilation of human adipose arterioles: ROS-induced ROS release in coronary artery disease. (Zinkevich NS, Fancher IS, Gutterman DD, Phillips SA) Microcirculation 2017 Aug;24(6)       33 Citations
1Communication Is Key: Mechanisms of Intercellular Signaling in Vasodilation. (Freed JK, Gutterman DD) J Cardiovasc Pharmacol 2017 May;69(5):264-272       37 Citations
1Sympathetic nervous system activation reduces contraction-induced rapid vasodilation in the leg of humans independent of age. (Hughes WE, Kruse NT, Casey DP) J Appl Physiol (1985) 2017 Jul 01;123(1):106-115       7 Citations
1Vasodilation of Isolated Vessels and the Isolation of the Extracellular Matrix of Tight-skin Mice. (Weihrauch D, Krolikowski JG, Jones DW, Zaman T, Bamkole O, Struve J, Pagel PS, Lohr NL, Pritchard KA Jr) J Vis Exp 2017 Mar 24(121)       2 Citations
3Moderate, Short-Term, Local Hyperglycemia Attenuates Forearm Endothelium-Dependent Vasodilation After Transient Ischemia-Reperfusion in Human Volunteers. (Ebert TJ, Novalija J, Barney JA, Uhrich TD, Arain SR, Freed JK, Pagel PS) J Cardiothorac Vasc Anesth 2017 Oct;31(5):1649-1655       2 Citations
3Mitochondria-regulated formation of endothelium-derived extracellular vesicles shifts the mediator of flow-induced vasodilation. (Freed JK, Durand MJ, Hoffmann BR, Densmore JC, Greene AS, Gutterman DD) Am J Physiol Heart Circ Physiol 2017 May 01;312(5):H1096-H1104       18 Citations
3Profound Hypotension After Anesthetic Induction in an Elderly Man With a Large Ascending Aortic Aneurysm: The Usual Anesthetic-Induced Vasodilation or a More Uncommon Mechanism? (Tanem JM, Plambeck CJ, Pagel PS, Boettcher BT) J Cardiothorac Vasc Anesth 2017 Oct;31(5):1916-1918    
1Diethyl-4,4'-dihydroxy-8,3'-neolign-7,7'-dien-9,9'-dionate exhibits antihypertensive activity in rats through increase in intracellular cGMP level and blockade of calcium channels. (Singh A, Kumar BS, Alam S, Iqbal H, Shafiq M, Khan F, Negi AS, Hanif K, Chanda D) Eur J Pharmacol 2017 Mar 15;799:84-93       13 Citations
1Impact of DPP-4 inhibition on acute and chronic endothelial function in humans with type 2 diabetes on background metformin therapy. (Widlansky ME, Puppala VK, Suboc TM, Malik M, Branum A, Signorelli K, Wang J, Ying R, Tanner MJ, Tyagi S) Vasc Med 2017 Jun;22(3):189-196       28 Citations
1PEGylated-nanoliposomal clusterin for amyloidogenic light chain-induced endothelial dysfunction. (Guzman-Villanueva D, Migrino RQ, Truran S, Karamanova N, Franco DA, Burciu C, Senapati S, Nedelkov D, Hari P, Weissig V) J Liposome Res 2018 Jun;28(2):97-105       4 Citations
15,6-δ-DHTL, a stable metabolite of arachidonic acid, is a potential EDHF that mediates microvascular dilation. (Levi-Rosenzvig R, Beyer AM, Hockenberry J, Ben-Shushan RS, Chuyun D, Atiya S, Tamir S, Gutterman DD, Szuchman-Sapir A) Free Radic Biol Med 2017 Feb;103:87-94       18 Citations
3Transition in the mechanism of flow-mediated dilation with aging and development of coronary artery disease. (Beyer AM, Zinkevich N, Miller B, Liu Y, Wittenburg AL, Mitchell M, Galdieri R, Sorokin A, Gutterman DD) Basic Res Cardiol 2017 Jan;112(1):5       73 Citations
1Dynamin-related protein 1 mediates low glucose-induced endothelial dysfunction in human arterioles. (Tanner MJ, Wang J, Ying R, Suboc TB, Malik M, Couillard A, Branum A, Puppala V, Widlansky ME) Am J Physiol Heart Circ Physiol 2017 Mar 01;312(3):H515-H527       27 Citations
2Contribution of KV1.5 Channel to Hydrogen Peroxide-Induced Human Arteriolar Dilation and Its Modulation by Coronary Artery Disease. (Nishijima Y, Cao S, Chabowski DS, Korishettar A, Ge A, Zheng X, Sparapani R, Gutterman DD, Zhang DX) Circ Res 2017 Feb 17;120(4):658-669       54 Citations
1Hypertension during Weight Lifting Reduces Flow-Mediated Dilation in Nonathletes. (Buchanan CE, Kadlec AO, Hoch AZ, Gutterman DD, Durand MJ) Med Sci Sports Exerc 2017 Apr;49(4):669-675       22 Citations
1Glabridin-induced vasorelaxation: Evidence for a role of BKCa channels and cyclic GMP. (Chanda D, Prieto-Lloret J, Singh A, Iqbal H, Yadav P, Snetkov V, Aaronson PI) Life Sci 2016 Nov 15;165:26-34       32 Citations
1Chronic vagal nerve stimulation prevents high-salt diet-induced endothelial dysfunction and aortic stiffening in stroke-prone spontaneously hypertensive rats. (Chapleau MW, Rotella DL, Reho JJ, Rahmouni K, Stauss HM) Am J Physiol Heart Circ Physiol 2016 Jul 01;311(1):H276-85       45 Citations
1The role of red blood cell S-nitrosation in nitrite bioactivation and its modulation by leucine and glucose. (Wajih N, Liu X, Shetty P, Basu S, Wu H, Hogg N, Patel RP, Furdui CM, Kim-Shapiro DB) Redox Biol 2016 Aug;8:415-21       19 Citations
1A splice variant of the myosin phosphatase regulatory subunit tunes arterial reactivity and suppresses response to salt loading. (Reho JJ, Kenchegowda D, Asico LD, Fisher SA) Am J Physiol Heart Circ Physiol 2016 Jun 01;310(11):H1715-24       10 Citations
4Vascular Actions of Angiotensin 1-7 in the Human Microcirculation: Novel Role for Telomerase. (Durand MJ, Zinkevich NS, Riedel M, Gutterman DD, Nasci VL, Salato VK, Hijjawi JB, Reuben CF, North PE, Beyer AM) Arterioscler Thromb Vasc Biol 2016 Jun;36(6):1254-62       57 Citations
1Chronic endurance exercise training offsets the age-related attenuation in contraction-induced rapid vasodilation. (Hughes WE, Ueda K, Casey DP) J Appl Physiol (1985) 2016 Jun 01;120(11):1335-42       13 Citations
1A 'passive' movement into the future of assessing endothelial dysfunction? (Hughes WE, Kruse NT) J Physiol 2016 Mar 15;594(6):1525-6       2 Citations
3The Human Microcirculation: Regulation of Flow and Beyond. (Gutterman DD, Chabowski DS, Kadlec AO, Durand MJ, Freed JK, Ait-Aissa K, Beyer AM) Circ Res 2016 Jan 08;118(1):157-72       255 Citations
1Chronic Co-Administration of Sepiapterin and L-Citrulline Ameliorates Diabetic Cardiomyopathy and Myocardial Ischemia/Reperfusion Injury in Obese Type 2 Diabetic Mice. (Baumgardt SL, Paterson M, Leucker TM, Fang J, Zhang DX, Bosnjak ZJ, Warltier DC, Kersten JR, Ge ZD) Circ Heart Fail 2016 Jan;9(1):e002424       54 Citations
1Brugia malayi Asparaginyl-tRNA Synthetase Stimulates Endothelial Cell Proliferation, Vasodilation and Angiogenesis. (D JJ, Dhanraj M, Solaiappan S, Sivanesan S, Kron M, Dhanasekaran A) PLoS One 2016;11(1):e0146132       13 Citations
4Critical Role for Telomerase in the Mechanism of Flow-Mediated Dilation in the Human Microcirculation. (Beyer AM, Freed JK, Durand MJ, Riedel M, Ait-Aissa K, Green P, Hockenberry JC, Morgan RG, Donato AJ, Peleg R, Gasparri M, Rokkas CK, Santos JH, Priel E, Gutterman DD) Circ Res 2016 Mar 04;118(5):856-66       95 Citations
2Vascular hepoxilin and trioxilins mediate vasorelaxation through TP receptor inhibition in mouse arteries. (Siangjong L, Goldman DH, Kriska T, Gauthier KM, Smyth EM, Puli N, Kumar G, Falck JR, Campbell WB) Acta Physiol (Oxf) 2017 Jan;219(1):188-201       19 Citations
1Endothelial PPAR-γ provides vascular protection from IL-1β-induced oxidative stress. (Mukohda M, Stump M, Ketsawatsomkron P, Hu C, Quelle FW, Sigmund CD) Am J Physiol Heart Circ Physiol 2016 Jan 01;310(1):H39-48       50 Citations
1Insomnia Symptoms Are Associated With Abnormal Endothelial Function. (Routledge FS, Dunbar SB, Higgins M, Rogers AE, Feeley C, Ioachimescu O, Euwer K, Eapen D, Quyyumi A) J Cardiovasc Nurs 2017;32(1):78-85       24 Citations
1The stress of maternal separation causes misprogramming in the postnatal maturation of rat resistance arteries. (Reho JJ, Fisher SA) Am J Physiol Heart Circ Physiol 2015 Nov;309(9):H1468-78       13 Citations
4Interaction of endothelial nitric oxide synthase with mitochondria regulates oxidative stress and function in fetal pulmonary artery endothelial cells. (Konduri GG, Afolayan AJ, Eis A, Pritchard KA Jr, Teng RJ) Am J Physiol Lung Cell Mol Physiol 2015 Nov 01;309(9):L1009-17       19 Citations
1Role of endothelial TRPV4 channels in vascular actions of the endocannabinoid, 2-arachidonoylglycerol. (Ho WS, Zheng X, Zhang DX) Br J Pharmacol 2015 Nov;172(22):5251-64       25 Citations
1Associations of Reducing Sedentary Time With Vascular Function and Insulin Sensitivity in Older Sedentary Adults. (Suboc TB, Knabel D, Strath SJ, Dharmashankar K, Coulliard A, Malik M, Haak K, Widlansky ME) Am J Hypertens 2016 Jan;29(1):46-53       15 Citations
1Mineralocorticoid exposure and receptor activity modulate microvascular endothelial function in African Americans with and without hypertension. (Mohandas A, Suboc TB, Wang J, Ying R, Tarima S, Dharmashankar K, Malik M, Widlansky ME) Vasc Med 2015 Oct;20(5):401-8       11 Citations
4Rap1 promotes endothelial mechanosensing complex formation, NO release and normal endothelial function. (Lakshmikanthan S, Zheng X, Nishijima Y, Sobczak M, Szabo A, Vasquez-Vivar J, Zhang DX, Chrzanowska-Wodnicka M) EMBO Rep 2015 May;16(5):628-37       49 Citations
1Redox signaling and splicing dependent change in myosin phosphatase underlie early versus late changes in NO vasodilator reserve in a mouse LPS model of sepsis. (Reho JJ, Zheng X, Asico LD, Fisher SA) Am J Physiol Heart Circ Physiol 2015 May 01;308(9):H1039-50       23 Citations
1[HYDROGEN SULFIDE DONOR, NAHS, RECOVERS CONSTITUTIVE NO SYNTHESIS AND ENDOTHELIUM-DEPENDENT RELAXATION OF ISOLATED AORTA IN OLD RATS]. (Drachuk KO, Kotsjuruba AV, Sagach VF) Fiziol Zh (1994) 2015;61(6):3-10       6 Citations
1TRA2β controls Mypt1 exon 24 splicing in the developmental maturation of mouse mesenteric artery smooth muscle. (Zheng X, Reho JJ, Wirth B, Fisher SA) Am J Physiol Cell Physiol 2015 Feb 15;308(4):C289-96       18 Citations
1Acute exertion elicits a H2O2-dependent vasodilator mechanism in the microvasculature of exercise-trained but not sedentary adults. (Durand MJ, Dharmashankar K, Bian JT, Das E, Vidovich M, Gutterman DD, Phillips SA) Hypertension 2015 Jan;65(1):140-5       54 Citations
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2An acute rise in intraluminal pressure shifts the mediator of flow-mediated dilation from nitric oxide to hydrogen peroxide in human arterioles. (Beyer AM, Durand MJ, Hockenberry J, Gamblin TC, Phillips SA, Gutterman DD) Am J Physiol Heart Circ Physiol 2014 Dec 01;307(11):H1587-93       64 Citations
1Role of peroxisome proliferator-activated receptor-γ in vascular muscle in the cerebral circulation. (De Silva TM, Modrick ML, Ketsawatsomkron P, Lynch C, Chu Y, Pelham CJ, Sigmund CD, Faraci FM) Hypertension 2014 Nov;64(5):1088-93       26 Citations
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3Ceramide changes the mediator of flow-induced vasodilation from nitric oxide to hydrogen peroxide in the human microcirculation. (Freed JK, Beyer AM, LoGiudice JA, Hockenberry JC, Gutterman DD) Circ Res 2014 Aug 15;115(5):525-32       113 Citations
4Rap1b in smooth muscle and endothelium is required for maintenance of vascular tone and normal blood pressure. (Lakshmikanthan S, Zieba BJ, Ge ZD, Momotani K, Zheng X, Lund H, Artamonov MV, Maas JE, Szabo A, Zhang DX, Auchampach JA, Mattson DL, Somlyo AV, Chrzanowska-Wodnicka M) Arterioscler Thromb Vasc Biol 2014 Jul;34(7):1486-94       49 Citations
2The vascular renin-angiotensin system contributes to blunted vasodilation induced by transient high pressure in human adipose microvessels. (Durand MJ, Phillips SA, Widlansky ME, Otterson MF, Gutterman DD) Am J Physiol Heart Circ Physiol 2014 Jul 01;307(1):H25-32       20 Citations
1Epoxyeicosatrienoic acid analogue lowers blood pressure through vasodilation and sodium channel inhibition. (Hye Khan MA, Pavlov TS, Christain SV, Neckář J, Staruschenko A, Gauthier KM, Capdevila JH, Falck JR, Campbell WB, Imig JD) Clin Sci (Lond) 2014 Oct;127(7):463-74       68 Citations
1Relative importance of step count, intensity, and duration on physical activity's impact on vascular structure and function in previously sedentary older adults. (Suboc TB, Strath SJ, Dharmashankar K, Coulliard A, Miller N, Wang J, Tanner MJ, Widlansky ME) J Am Heart Assoc 2014 Feb 26;3(1):e000702       65 Citations
3Amelioration of salt-induced vascular dysfunction in mesenteric arteries of Dahl salt-sensitive rats by missense mutation of extracellular superoxide dismutase. (Beyer AM, Raffai G, Weinberg BD, Fredrich K, Rodgers MS, Geurts AM, Jacob HJ, Dwinell MR, Lombard JH) Am J Physiol Heart Circ Physiol 2014 Feb;306(3):H339-47       11 Citations
1Endothelial metabolism of angiotensin II to angiotensin III, not angiotensin (1-7), augments the vasorelaxation response in adrenal cortical arteries. (Kopf PG, Campbell WB) Endocrinology 2013 Dec;154(12):4768-76       10 Citations
3Inhibition of myeloperoxidase decreases vascular oxidative stress and increases vasodilatation in sickle cell disease mice. (Zhang H, Xu H, Weihrauch D, Jones DW, Jing X, Shi Y, Gourlay D, Oldham KT, Hillery CA, Pritchard KA Jr) J Lipid Res 2013 Nov;54(11):3009-15       40 Citations
4Effect of human 15-lipoxygenase-1 metabolites on vascular function in mouse mesenteric arteries and hearts. (Kriska T, Cepura C, Siangjong L, Wan TC, Auchampach JA, Shaish A, Haratz D, Kumar G, Falck JR, Gauthier KM, Campbell WB) Prostaglandins Other Lipid Mediat 2013 Oct;106:8-15       7 Citations
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1Low-dose angiotensin II infusion restores vascular function in cerebral arteries of high salt-fed rats by increasing copper/zinc superoxide dimutase expression. (Durand MJ, Lombard JH) Am J Hypertens 2013 Jun;26(6):739-47       39 Citations
1Diversity in mechanisms of endothelium-dependent vasodilation in health and disease. (Durand MJ, Gutterman DD) Microcirculation 2013 Apr;20(3):239-47       166 Citations
1Ecto-5'-nucleotidase, CD73, is an endothelium-derived hyperpolarizing factor synthase. (Ohta M, Toyama K, Gutterman DD, Campbell WB, Lemaître V, Teraoka R, Miura H) Arterioscler Thromb Vasc Biol 2013 Mar;33(3):629-36       30 Citations
1Inducible endothelium-derived hyperpolarizing factor: role of the 15-lipoxygenase-EDHF pathway. (Campbell WB, Gauthier KM) J Cardiovasc Pharmacol 2013 Mar;61(3):176-87       32 Citations
2A novel hemoglobin-binding peptide reduces cell-free hemoglobin in murine hemolytic anemia. (Hanson MS, Xu H, Flewelen TC, Holzhauer SL, Retherford D, Jones DW, Frei AC, Pritchard KA Jr, Hillery CA, Hogg N, Wandersee NJ) Am J Physiol Heart Circ Physiol 2013 Jan 15;304(2):H328-36       13 Citations
1Protective role of clusterin in preserving endothelial function in AL amyloidosis. (Franco DA, Truran S, Burciu C, Gutterman DD, Maltagliati A, Weissig V, Hari P, Migrino RQ) Atherosclerosis 2012 Nov;225(1):220-3       17 Citations
3Decreases in manganese superoxide dismutase expression and activity contribute to oxidative stress in persistent pulmonary hypertension of the newborn. (Afolayan AJ, Eis A, Teng RJ, Bakhutashvili I, Kaul S, Davis JM, Konduri GG) Am J Physiol Lung Cell Mol Physiol 2012 Nov 15;303(10):L870-9       68 Citations
1Impact of maternal dexamethasone on coronary PGE(2) production and prostaglandin-dependent coronary reactivity. (Roghair RD, Volk KA, Lamb FS, Segar JL) Am J Physiol Regul Integr Comp Physiol 2012 Sep 01;303(5):R513-9       3 Citations
1Sex-specific programming of hypertension in offspring of late-gestation diabetic rats. (Katkhuda R, Peterson ES, Roghair RD, Norris AW, Scholz TD, Segar JL) Pediatr Res 2012 Oct;72(4):352-61       36 Citations
1Dahl salt-sensitive rats are protected against vascular defects related to diet-induced obesity. (Beyer AM, Raffai G, Weinberg B, Fredrich K, Lombard JH) Hypertension 2012 Aug;60(2):404-10       27 Citations
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2Mice lacking macrophage 12/15-lipoxygenase are resistant to experimental hypertension. (Kriska T, Cepura C, Magier D, Siangjong L, Gauthier KM, Campbell WB) Am J Physiol Heart Circ Physiol 2012 Jun 01;302(11):H2428-38       41 Citations
1Nitric oxide synthase-dependent vasodilation of human subcutaneous arterioles correlates with noninvasive measurements of endothelial function. (Dharmashankar K, Welsh A, Wang J, Kizhakekuttu TJ, Ying R, Gutterman DD, Widlansky ME) Am J Hypertens 2012 May;25(5):528-34       33 Citations
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1Hexosamine pathway activation and O-linked-N-acetylglucosamine: novel mediators of endothelial dysfunction in hyperglycemia and diabetes. (Beyer AM, Weihrauch D) Vascul Pharmacol 2012;56(3-4):113-4       7 Citations
1Endothelial nitric oxide and 15-lipoxygenase-1 metabolites independently mediate relaxation of the rabbit aorta. (Aggarwal NT, Gauthier KM, Campbell WB) Vascul Pharmacol 2012;56(1-2):106-12       5 Citations
2H2O2-induced dilation in human coronary arterioles: role of protein kinase G dimerization and large-conductance Ca2+-activated K+ channel activation. (Zhang DX, Borbouse L, Gebremedhin D, Mendoza SA, Zinkevich NS, Li R, Gutterman DD) Circ Res 2012 Feb 03;110(3):471-80       143 Citations
2Activation of endothelial TRPV4 channels mediates flow-induced dilation in human coronary arterioles: role of Ca2+ entry and mitochondrial ROS signaling. (Bubolz AH, Mendoza SA, Zheng X, Zinkevich NS, Li R, Gutterman DD, Zhang DX) Am J Physiol Heart Circ Physiol 2012 Feb 01;302(3):H634-42       133 Citations
1Nitroglycerin drives endothelial nitric oxide synthase activation via the phosphatidylinositol 3-kinase/protein kinase B pathway. (Mao M, Sudhahar V, Ansenberger-Fricano K, Fernandes DC, Tanaka LY, Fukai T, Laurindo FR, Mason RP, Vasquez-Vivar J, Minshall RD, Stadler K, Bonini MG) Free Radic Biol Med 2012 Jan 15;52(2):427-35       22 Citations
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1Human microvascular dysfunction and apoptotic injury induced by AL amyloidosis light chain proteins. (Migrino RQ, Truran S, Gutterman DD, Franco DA, Bright M, Schlundt B, Timmons M, Motta A, Phillips SA, Hari P) Am J Physiol Heart Circ Physiol 2011 Dec;301(6):H2305-12       76 Citations
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1Soluble epoxide hydrolase contamination of specific catalase preparations inhibits epoxyeicosatrienoic acid vasodilation of rat renal arterioles. (Gauthier KM, Olson L, Harder A, Isbell M, Imig JD, Gutterman DD, Falck JR, Campbell WB) Am J Physiol Renal Physiol 2011 Oct;301(4):F765-72       4 Citations
3Folic acid supplementation improves vascular function in professional dancers with endothelial dysfunction. (Hoch AZ, Papanek P, Szabo A, Widlansky ME, Gutterman DD) PM R 2011 Nov;3(11):1005-12       16 Citations
1PKCα mediates acetylcholine-induced activation of TRPV4-dependent calcium influx in endothelial cells. (Adapala RK, Talasila PK, Bratz IN, Zhang DX, Suzuki M, Meszaros JG, Thodeti CK) Am J Physiol Heart Circ Physiol 2011 Sep;301(3):H757-65       88 Citations
2The female athlete triad and endothelial dysfunction. (Lanser EM, Zach KN, Hoch AZ) PM R 2011 May;3(5):458-65       25 Citations
1Dietary nitrate supplementation enhances exercise performance in peripheral arterial disease. (Kenjale AA, Ham KL, Stabler T, Robbins JL, Johnson JL, Vanbruggen M, Privette G, Yim E, Kraus WE, Allen JD) J Appl Physiol (1985) 2011 Jun;110(6):1582-91       259 Citations
1Resistance and aerobic exercise protects against acute endothelial impairment induced by a single exposure to hypertension during exertion. (Phillips SA, Das E, Wang J, Pritchard K, Gutterman DD) J Appl Physiol (1985) 2011 Apr;110(4):1013-20       88 Citations
1H2O2 is the transferrable factor mediating flow-induced dilation in human coronary arterioles. (Liu Y, Bubolz AH, Mendoza S, Zhang DX, Gutterman DD) Circ Res 2011 Mar 04;108(5):566-73       150 Citations
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2Angiotensin II regulates adrenal vascular tone through zona glomerulosa cell-derived EETs and DHETs. (Kopf PG, Gauthier KM, Zhang DX, Falck JR, Campbell WB) Hypertension 2011 Feb;57(2):323-9       19 Citations
1Absence of deterioration of vascular function of the donor limb at late follow-up after radial artery harvesting. (Schena S, Crabtree TD, Baker KA, Guthrie TJ, Curci J, Damiano RJ, Barner HB) J Thorac Cardiovasc Surg 2011 Aug;142(2):298-301       8 Citations
1The potential role of the red blood cell in nitrite-dependent regulation of blood flow. (Patel RP, Hogg N, Kim-Shapiro DB) Cardiovasc Res 2011 Feb 15;89(3):507-15       53 Citations
1Assessment of flow-mediated dilation in humans: a methodological and physiological guideline. (Thijssen DH, Black MA, Pyke KE, Padilla J, Atkinson G, Harris RA, Parker B, Widlansky ME, Tschakovsky ME, Green DJ) Am J Physiol Heart Circ Physiol 2011 Jan;300(1):H2-12       1241 Citations
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1Transient receptor potential channel activation and endothelium-dependent dilation in the systemic circulation. (Zhang DX, Gutterman DD) J Cardiovasc Pharmacol 2011 Feb;57(2):133-9       70 Citations
1Contrasting vascular effects caused by loss of Bardet-Biedl syndrome genes. (Beyer AM, Guo DF, Sheffield VC, Rahmouni K) Am J Physiol Heart Circ Physiol 2010 Dec;299(6):H1902-7       13 Citations
1Impaired relaxation of cerebral arteries in the absence of elevated salt intake in normotensive congenic rats carrying the Dahl salt-sensitive renin gene. (Durand MJ, Moreno C, Greene AS, Lombard JH) Am J Physiol Heart Circ Physiol 2010 Dec;299(6):H1865-74       21 Citations
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1Angiotensin-(1-7) and low-dose angiotensin II infusion reverse salt-induced endothelial dysfunction via different mechanisms in rat middle cerebral arteries. (Durand MJ, Raffai G, Weinberg BD, Lombard JH) Am J Physiol Heart Circ Physiol 2010 Oct;299(4):H1024-33       48 Citations
1The danger of sedenterism: endothelium at risk. (Widlansky ME) Am J Physiol Heart Circ Physiol 2010 Aug;299(2):H243-4       10 Citations
3Genetic deletion of apolipoprotein A-I increases airway hyperresponsiveness, inflammation, and collagen deposition in the lung. (Wang W, Xu H, Shi Y, Nandedkar S, Zhang H, Gao H, Feroah T, Weihrauch D, Schulte ML, Jones DW, Jarzembowski J, Sorci-Thomas M, Pritchard KA Jr) J Lipid Res 2010 Sep;51(9):2560-70       77 Citations
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2Adrenic acid metabolites as endogenous endothelium-derived and zona glomerulosa-derived hyperpolarizing factors. (Kopf PG, Zhang DX, Gauthier KM, Nithipatikom K, Yi XY, Falck JR, Campbell WB) Hypertension 2010 Feb;55(2):547-54       38 Citations
2TRPV4-mediated endothelial Ca2+ influx and vasodilation in response to shear stress. (Mendoza SA, Fang J, Gutterman DD, Wilcox DA, Bubolz AH, Li R, Suzuki M, Zhang DX) Am J Physiol Heart Circ Physiol 2010 Feb;298(2):H466-76       286 Citations
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1Angiotensin II maintains cerebral vascular relaxation via EGF receptor transactivation and ERK1/2. (McEwen ST, Balus SF, Durand MJ, Lombard JH) Am J Physiol Heart Circ Physiol 2009 Oct;297(4):H1296-303       17 Citations
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2Lipid-induced insulin resistance is associated with increased monocyte expression of scavenger receptor CD36 and internalization of oxidized LDL. (Kashyap SR, Ioachimescu AG, Gornik HL, Gopan T, Davidson MB, Makdissi A, Major J, Febbraio M, Silverstein RL) Obesity (Silver Spring) 2009 Dec;17(12):2142-8       53 Citations
1Effect of the effluent released from the canine internal mammary artery after intraluminal and extraluminal perfusion of acetylcholine and adenosine diphosphate. (Matsuda NM, Pearson PJ, Schaff HV, Piccinato CE, Rodrigues AJ, Evora PR) J Biomed Sci 2009 May 05;16(1):45       1 Citation
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2Parstatin: a cryptic peptide involved in cardioprotection after ischaemia and reperfusion injury. (Strande JL, Widlansky ME, Tsopanoglou NE, Su J, Wang J, Hsu A, Routhu KV, Baker JE) Cardiovasc Res 2009 Jul 15;83(2):325-34       21 Citations
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1Comparisons of the release of vasodilator substances from left and right cardiac chambers of the isolated perfused rabbit heart: implications for intraventricular thrombus formation. (Discigil B, Chua YL, Pearson PJ, Evora PR, Celotto AC, Schaff HV) Nitric Oxide 2009 Jun;20(4):259-63       2 Citations
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1Bradykinin-induced dilation of human coronary arterioles requires NADPH oxidase-derived reactive oxygen species. (Larsen BT, Bubolz AH, Mendoza SA, Pritchard KA Jr, Gutterman DD) Arterioscler Thromb Vasc Biol 2009 May;29(5):739-45       65 Citations
1Programming of growth, insulin resistance and vascular dysfunction in offspring of late gestation diabetic rats. (Segar EM, Norris AW, Yao JR, Hu S, Koppenhafer SL, Roghair RD, Segar JL, Scholz TD) Clin Sci (Lond) 2009 Jul 02;117(3):129-38       40 Citations
1Transient receptor potential vanilloid type 4-deficient mice exhibit impaired endothelium-dependent relaxation induced by acetylcholine in vitro and in vivo. (Zhang DX, Mendoza SA, Bubolz AH, Mizuno A, Ge ZD, Li R, Warltier DC, Suzuki M, Gutterman DD) Hypertension 2009 Mar;53(3):532-8       174 Citations
3Chronic hypoxia enhances 15-lipoxygenase-mediated vasorelaxation in rabbit arteries. (Aggarwal NT, Pfister SL, Gauthier KM, Chawengsub Y, Baker JE, Campbell WB) Am J Physiol Heart Circ Physiol 2009 Mar;296(3):H678-88       11 Citations
1Shear stress and flow-mediated dilation: all shear responses are not created equally. (Widlansky ME) Am J Physiol Heart Circ Physiol 2009 Jan;296(1):H31-2       12 Citations
2Hypercholesterolemia enhances 15-lipoxygenase-mediated vasorelaxation and acetylcholine-induced hypotension. (Aggarwal NT, Pfister SL, Campbell WB) Arterioscler Thromb Vasc Biol 2008 Dec;28(12):2209-15       12 Citations
1High-frequency ultrasonic waves cause endothelial dysfunction on canine epicardial coronary arteries. (Discigil B, King RM, Pearson PJ, Capellini VK, Rodrigues AJ, Schaff HV, Evora PR) Rev Bras Cir Cardiovasc 2008;23(2):190-6       2 Citations
1Sex-specific differences in chromosome-dependent regulation of vascular reactivity in female consomic rat strains from a SSxBN cross. (Kunert MP, Dwinell MR, Drenjancevic Peric I, Lombard JH) Am J Physiol Regul Integr Comp Physiol 2008 Aug;295(2):R516-27       11 Citations
2Angiotensin II relaxations of bovine adrenal cortical arteries: role of angiotensin II metabolites and endothelial nitric oxide. (Gauthier KM, Zhang DX, Cui L, Nithipatikom K, Campbell WB) Hypertension 2008 Jul;52(1):150-5       13 Citations
2Vascular dysfunction in a murine model of severe hemolysis. (Frei AC, Guo Y, Jones DW, Pritchard KA Jr, Fagan KA, Hogg N, Wandersee NJ) Blood 2008 Jul 15;112(2):398-405       43 Citations
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1Endothelial cytoskeletal elements are critical for flow-mediated dilation in human coronary arterioles. (Liu Y, Li H, Bubolz AH, Zhang DX, Gutterman DD) Med Biol Eng Comput 2008 May;46(5):469-78       58 Citations
2Interference with PPAR gamma function in smooth muscle causes vascular dysfunction and hypertension. (Halabi CM, Beyer AM, de Lange WJ, Keen HL, Baumbach GL, Faraci FM, Sigmund CD) Cell Metab 2008 Mar;7(3):215-26       152 Citations
1Benefit of low-fat over low-carbohydrate diet on endothelial health in obesity. (Phillips SA, Jurva JW, Syed AQ, Syed AQ, Kulinski JP, Pleuss J, Hoffmann RG, Gutterman DD) Hypertension 2008 Feb;51(2):376-82       73 Citations
1Endothelial 15-lipoxygenase-1 overexpression increases acetylcholine-induced hypotension and vasorelaxation in rabbits. (Aggarwal NT, Chawengsub Y, Gauthier KM, Viita H, Yla-Herttuala S, Campbell WB) Hypertension 2008 Feb;51(2):246-51       18 Citations
1Metabolic syndrome, insulin resistance, and brachial artery vasodilator function in Framingham Offspring participants without clinical evidence of cardiovascular disease. (Hamburg NM, Larson MG, Vita JA, Vasan RS, Keyes MJ, Widlansky ME, Fox CS, Mitchell GF, Levy D, Meigs JB, Benjamin EJ) Am J Cardiol 2008 Jan 01;101(1):82-8       94 Citations
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1Betamethasone attenuates oxidant stress in endothelial cells from fetal lambs with persistent pulmonary hypertension. (Chandrasekar I, Eis A, Konduri GG) Pediatr Res 2008 Jan;63(1):67-72       45 Citations
1Hydrogen peroxide inhibits cytochrome p450 epoxygenases: interaction between two endothelium-derived hyperpolarizing factors. (Larsen BT, Gutterman DD, Sato A, Toyama K, Campbell WB, Zeldin DC, Manthati VL, Falck JR, Miura H) Circ Res 2008 Jan 04;102(1):59-67       89 Citations
1Physical inactivity rapidly induces insulin resistance and microvascular dysfunction in healthy volunteers. (Hamburg NM, McMackin CJ, Huang AL, Shenouda SM, Widlansky ME, Schulz E, Gokce N, Ruderman NB, Keaney JF Jr, Vita JA) Arterioscler Thromb Vasc Biol 2007 Dec;27(12):2650-6       362 Citations
1Relation of season and temperature to endothelium-dependent flow-mediated vasodilation in subjects without clinical evidence of cardiovascular disease (from the Framingham Heart Study). (Widlansky ME, Vita JA, Keyes MJ, Larson MG, Hamburg NM, Levy D, Mitchell GF, Osypiuk EW, Vasan RS, Benjamin EJ) Am J Cardiol 2007 Aug 01;100(3):518-23       78 Citations
1Endothelial superoxide production is altered in sheep programmed by early gestation dexamethasone exposure. (Roghair RD, Miller FJ Jr, Scholz TD, Lamb FS, Segar JL) Neonatology 2008;93(1):19-27       22 Citations
1Acute EGCG supplementation reverses endothelial dysfunction in patients with coronary artery disease. (Widlansky ME, Hamburg NM, Anter E, Holbrook M, Kahn DF, Elliott JG, Keaney JF Jr, Vita JA) J Am Coll Nutr 2007 Apr;26(2):95-102       204 Citations
2Effects of D-4F on vasodilation, oxidative stress, angiostatin, myocardial inflammation, and angiogenic potential in tight-skin mice. (Weihrauch D, Xu H, Shi Y, Wang J, Brien J, Jones DW, Kaul S, Komorowski RA, Csuka ME, Oldham KT, Pritchard KA) Am J Physiol Heart Circ Physiol 2007 Sep;293(3):H1432-41       71 Citations
2Steroid-producing cells regulate arterial tone of adrenal cortical arteries. (Zhang DX, Gauthier KM, Falck JR, Siddam A, Campbell WB) Endocrinology 2007 Aug;148(8):3569-76       15 Citations
1Effect of combined treatment with alpha-Lipoic acid and acetyl-L-carnitine on vascular function and blood pressure in patients with coronary artery disease. (McMackin CJ, Widlansky ME, Hamburg NM, Huang AL, Weller S, Holbrook M, Gokce N, Hagen TM, Keaney JF Jr, Vita JA) J Clin Hypertens (Greenwich) 2007 Apr;9(4):249-55       88 Citations
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1Characterization of 14,15-epoxyeicosatrienoyl-sulfonamides as 14,15-epoxyeicosatrienoic acid agonists: use for studies of metabolism and ligand binding. (Yang W, Holmes BB, Gopal VR, Kishore RV, Sangras B, Yi XY, Falck JR, Campbell WB) J Pharmacol Exp Ther 2007 Jun;321(3):1023-31       43 Citations
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1Metabolism of adrenic acid to vasodilatory 1alpha,1beta-dihomo-epoxyeicosatrienoic acids by bovine coronary arteries. (Yi XY, Gauthier KM, Cui L, Nithipatikom K, Falck JR, Campbell WB) Am J Physiol Heart Circ Physiol 2007 May;292(5):H2265-74       29 Citations
1Arachidonic acid metabolites as endothelium-derived hyperpolarizing factors. (Campbell WB, Falck JR) Hypertension 2007 Mar;49(3):590-6       185 Citations
1Beyond vasodilatation: non-vasomotor roles of epoxyeicosatrienoic acids in the cardiovascular system. (Larsen BT, Campbell WB, Gutterman DD) Trends Pharmacol Sci 2007 Jan;28(1):32-8       74 Citations
1Oxidant stress from uncoupled nitric oxide synthase impairs vasodilation in fetal lambs with persistent pulmonary hypertension. (Konduri GG, Bakhutashvili I, Eis A, Pritchard K Jr) Am J Physiol Heart Circ Physiol 2007 Apr;292(4):H1812-20       108 Citations
2Endothelium-derived microparticles induce endothelial dysfunction and acute lung injury. (Densmore JC, Signorino PR, Ou J, Hatoum OA, Rowe JJ, Shi Y, Kaul S, Jones DW, Sabina RE, Pritchard KA Jr, Guice KS, Oldham KT) Shock 2006 Nov;26(5):464-71       163 Citations
1Adenoviral expression of 15-lipoxygenase-1 in rabbit aortic endothelium: role in arachidonic acid-induced relaxation. (Aggarwal NT, Holmes BB, Cui L, Viita H, Yla-Herttuala S, Campbell WB) Am J Physiol Heart Circ Physiol 2007 Feb;292(2):H1033-41       14 Citations
1Radical scavenging and NO-releasing properties of selected beta-adrenoreceptor antagonists. (Szajerski P, Zielonka J, Sikora A, Adamus J, Marcinek A, Gebicki J, Kozlovski VI, Drelicharz L, Chłopicki S) Free Radic Res 2006 Jul;40(7):741-52       17 Citations
1Ceruloplasmin is a NO oxidase and nitrite synthase that determines endocrine NO homeostasis. (Shiva S, Wang X, Ringwood LA, Xu X, Yuditskaya S, Annavajjhala V, Miyajima H, Hogg N, Harris ZL, Gladwin MT) Nat Chem Biol 2006 Sep;2(9):486-93       328 Citations
1Nitrite as a vascular endocrine nitric oxide reservoir that contributes to hypoxic signaling, cytoprotection, and vasodilation. (Gladwin MT, Raat NJ, Shiva S, Dezfulian C, Hogg N, Kim-Shapiro DB, Patel RP) Am J Physiol Heart Circ Physiol 2006 Nov;291(5):H2026-35       294 Citations
1Resistance to pressure-induced dilatation in femoral but not saphenous artery: physiological role of latch? (Call C, Han S, Speich JE, Eddinger TJ, Ratz PH) Am J Physiol Heart Circ Physiol 2006 Oct;291(4):H1513-20       5 Citations
1A role for heterocellular coupling and EETs in dilation of rat cremaster arteries. (McSherry IN, Sandow SL, Campbell WB, Falck JR, Hill MA, Dora KA) Microcirculation 2006 Mar;13(2):119-30       52 Citations
2Vasodilation from sufentanil in humans. (Ebert TJ, Ficke DJ, Arain SR, Holtz MN, Shankar H) Anesth Analg 2005 Dec;101(6):1677-1680       21 Citations
1Epoxyeicosatrienoic and dihydroxyeicosatrienoic acids dilate human coronary arterioles via BK(Ca) channels: implications for soluble epoxide hydrolase inhibition. (Larsen BT, Miura H, Hatoum OA, Campbell WB, Hammock BD, Zeldin DC, Falck JR, Gutterman DD) Am J Physiol Heart Circ Physiol 2006 Feb;290(2):H491-9       158 Citations
2Reticulocyte 15-lipoxygenase-I is important in acetylcholine-induced endothelium-dependent vasorelaxation in rabbit aorta. (Tang X, Holmes BB, Nithipatikom K, Hillard CJ, Kuhn H, Campbell WB) Arterioscler Thromb Vasc Biol 2006 Jan;26(1):78-84       29 Citations
3Effects of D-4F on vasodilation and vessel wall thickness in hypercholesterolemic LDL receptor-null and LDL receptor/apolipoprotein A-I double-knockout mice on Western diet. (Ou J, Wang J, Xu H, Ou Z, Sorci-Thomas MG, Jones DW, Signorino P, Densmore JC, Kaul S, Oldham KT, Pritchard KA Jr) Circ Res 2005 Nov 25;97(11):1190-7       114 Citations
2Peroxynitrite reduces the endothelium-derived hyperpolarizing factor component of coronary flow-mediated dilation in PECAM-1-knockout mice. (Liu Y, Bubolz AH, Shi Y, Newman PJ, Newman DK, Gutterman DD) Am J Physiol Regul Integr Comp Physiol 2006 Jan;290(1):R57-65       40 Citations
1Serine 68 phospholemman phosphorylation during forskolin-induced swine carotid artery relaxation. (Rembold CM, Ripley ML, Meeks MK, Geddis LM, Kutchai HC, Marassi FM, Cheung JY, Moorman JR) J Vasc Res 2005;42(6):483-91       28 Citations
1eNOS function is developmentally regulated: uncoupling of eNOS occurs postnatally. (Mata-Greenwood E, Jenkins C, Farrow KN, Konduri GG, Russell JA, Lakshminrusimha S, Black SM, Steinhorn RH) Am J Physiol Lung Cell Mol Physiol 2006 Feb;290(2):L232-41       60 Citations
1Novel mechanism of vasodilation in inflammatory bowel disease. (Hatoum OA, Gauthier KM, Binion DG, Miura H, Telford G, Otterson MF, Campbell WB, Gutterman DD) Arterioscler Thromb Vasc Biol 2005 Nov;25(11):2355-61       27 Citations
1Enzymatic function of hemoglobin as a nitrite reductase that produces NO under allosteric control. (Huang Z, Shiva S, Kim-Shapiro DB, Patel RP, Ringwood LA, Irby CE, Huang KT, Ho C, Hogg N, Schechter AN, Gladwin MT) J Clin Invest 2005 Aug;115(8):2099-107       463 Citations
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1Stable 5,6-epoxyeicosatrienoic acid analog relaxes coronary arteries through potassium channel activation. (Yang W, Gauthier KM, Reddy LM, Sangras B, Sharma KK, Nithipatikom K, Falck JR, Campbell WB) Hypertension 2005 Apr;45(4):681-6       23 Citations
1The reaction between nitrite and hemoglobin: the role of nitrite in hemoglobin-mediated hypoxic vasodilation. (Kim-Shapiro DB, Gladwin MT, Patel RP, Hogg N) J Inorg Biochem 2005 Jan;99(1):237-46       160 Citations
2Endothelium-derived 2-arachidonylglycerol: an intermediate in vasodilatory eicosanoid release in bovine coronary arteries. (Gauthier KM, Baewer DV, Hittner S, Hillard CJ, Nithipatikom K, Reddy DS, Falck JR, Campbell WB) Am J Physiol Heart Circ Physiol 2005 Mar;288(3):H1344-51       67 Citations
1Effect of active muscle mass during ischemic exercise on peak lower leg vascular conductance. (Polichnowski AJ, Heyer EK, Ng AV) J Appl Physiol (1985) 2005 Mar;98(3):765-71       5 Citations
2Cyclooxygenase- and lipoxygenase-dependent relaxation to arachidonic acid in rabbit small mesenteric arteries. (Zhang DX, Gauthier KM, Chawengsub Y, Holmes BB, Campbell WB) Am J Physiol Heart Circ Physiol 2005 Jan;288(1):H302-9       21 Citations
1Structure of cerebral arterioles in mice deficient in expression of the gene for endothelial nitric oxide synthase. (Baumbach GL, Sigmund CD, Faraci FM) Circ Res 2004 Oct 15;95(8):822-9       64 Citations
1Endothelium-dependent vasodilation during acute rejection in dogs. (Pearson PJ, Wei CM, Lin PJ, Burnett JC, Cable DG, Hamner CE, Schaff HV) J Surg Res 2004 Sep;121(1):56-61       2 Citations
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2Acetylcholine-induced relaxation and hyperpolarization in small bovine adrenal cortical arteries: role of cytochrome P450 metabolites. (Zhang DX, Gauthier KM, Campbell WB) Endocrinology 2004 Oct;145(10):4532-9       9 Citations
1Cerebral vascular dysfunction mediated by superoxide in hyperhomocysteinemic mice. (Dayal S, Arning E, Bottiglieri T, Böger RH, Sigmund CD, Faraci FM, Lentz SR) Stroke 2004 Aug;35(8):1957-62       146 Citations
1Transduction of NO-bioactivity by the red blood cell in sepsis: novel mechanisms of vasodilation during acute inflammatory disease. (Crawford JH, Chacko BK, Pruitt HM, Piknova B, Hogg N, Patel RP) Blood 2004 Sep 01;104(5):1375-82       101 Citations
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1P2Y purine receptor responses and expression in the pulmonary circulation of juvenile rabbits. (Konduri GG, Bakhutashvili I, Frenn R, Chandrasekhar I, Jacobs ER, Khanna AK) Am J Physiol Heart Circ Physiol 2004 Jul;287(1):H157-64       28 Citations
1PPAR(gamma) agonist rosiglitazone improves vascular function and lowers blood pressure in hypertensive transgenic mice. (Ryan MJ, Didion SP, Mathur S, Faraci FM, Sigmund CD) Hypertension 2004 Mar;43(3):661-6       177 Citations
2Characterization of vasoconstrictor responses in small bovine adrenal cortical arteries in vitro. (Zhang DX, Gauthier KM, Campbell WB) Endocrinology 2004 Apr;145(4):1571-8       15 Citations
1Apamin-sensitive K+ currents mediate arachidonic acid-induced relaxations of rabbit aorta. (Gauthier KM, Spitzbarth N, Edwards EM, Campbell WB) Hypertension 2004 Feb;43(2):413-9       41 Citations
1A novel antioxidant, EPC-K1, stimulates endothelial nitric oxide production and scavenges hydroxyl radicals. (Takayama H, Hamner CE, Caccitolo JA, Hisamochi K, Pearson PJ, Schaff HV) Circ J 2003 Dec;67(12):1046-52       11 Citations
1Abnormal coronary function in mice deficient in alpha1H T-type Ca2+ channels. (Chen CC, Lamping KG, Nuno DW, Barresi R, Prouty SJ, Lavoie JL, Cribbs LL, England SK, Sigmund CD, Weiss RM, Williamson RA, Hill JA, Campbell KP) Science 2003 Nov 21;302(5649):1416-8       310 Citations
1Heat shock protein 90 and tyrosine kinase regulate eNOS NO* generation but not NO* bioactivity. (Ou J, Fontana JT, Ou Z, Jones DW, Ackerman AW, Oldham KT, Yu J, Sessa WC, Pritchard KA Jr) Am J Physiol Heart Circ Physiol 2004 Feb;286(2):H561-9       53 Citations
1Interleukin-13 upregulates vasodilatory 15-lipoxygenase eicosanoids in rabbit aorta. (Tang X, Spitzbarth N, Kuhn H, Chaitidis P, Campbell WB) Arterioscler Thromb Vasc Biol 2003 Oct 01;23(10):1768-74       16 Citations
1Mitochondrial sources of H2O2 generation play a key role in flow-mediated dilation in human coronary resistance arteries. (Liu Y, Zhao H, Li H, Kalyanaraman B, Nicolosi AC, Gutterman DD) Circ Res 2003 Sep 19;93(6):573-80       295 Citations
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1Short- and long-term COX-2 inhibition reverses endothelial dysfunction in patients with hypertension. (Widlansky ME, Price DT, Gokce N, Eberhardt RT, Duffy SJ, Holbrook M, Maxwell C, Palmisano J, Keaney JF Jr, Morrow JD, Vita JA) Hypertension 2003 Sep;42(3):310-5       149 Citations
1Endothelium-dependent relaxation in response to poly-L-arginine in canine coronary arteries: implications about hyperpolarization as a mechanism of vasodilatation. (Evora PR, Pearson PJ, Rodrigues AJ, Viaro F, Schaff HV) Arq Bras Cardiol 2003 Jun;80(6):626-30; 621-5       1 Citation
2Metabolism of 12-hydroperoxyeicosatetraenoic acid to vasodilatory trioxilin C3 by rabbit aorta. (Pfister SL, Spitzbarth N, Nithipatikom K, Falck JR, Campbell WB) Biochim Biophys Acta 2003 Jun 20;1622(1):6-13       16 Citations
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1Increased H(2)O(2) counteracts the vasodilator and natriuretic effects of superoxide dismutation by tempol in renal medulla. (Chen YF, Cowley AW Jr, Zou AP) Am J Physiol Regul Integr Comp Physiol 2003 Oct;285(4):R827-33       111 Citations
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1Urotensin II is a nitric oxide-dependent vasodilator and natriuretic peptide in the rat kidney. (Zhang AY, Chen YF, Zhang DX, Yi FX, Qi J, Andrade-Gordon P, de Garavilla L, Li PL, Zou AP) Am J Physiol Renal Physiol 2003 Oct;285(4):F792-8       99 Citations
1L-4F, an apolipoprotein A-1 mimetic, dramatically improves vasodilation in hypercholesterolemia and sickle cell disease. (Ou J, Ou Z, Jones DW, Holzhauer S, Hatoum OA, Ackerman AW, Weihrauch DW, Gutterman DD, Guice K, Oldham KT, Hillery CA, Pritchard KA Jr) Circulation 2003 May 13;107(18):2337-41       143 Citations
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1Endothelium-derived hyperpolarizing factor in human internal mammary artery is 11,12-epoxyeicosatrienoic acid and causes relaxation by activating smooth muscle BK(Ca) channels. (Archer SL, Gragasin FS, Wu X, Wang S, McMurtry S, Kim DH, Platonov M, Koshal A, Hashimoto K, Campbell WB, Falck JR, Michelakis ED) Circulation 2003 Feb 11;107(5):769-76       236 Citations
1What leads to different mediators of alkalosis-induced vasodilation in isolated and in situ pulmonary vessels? (Gordon JB, VanderHeyden MA, Halla TR, Cortez EP, Hernandez G, Haworth ST, Dawson CA, Madden JA) Am J Physiol Lung Cell Mol Physiol 2003 May;284(5):L799-807       10 Citations
1Cerebral arteriolar structure in mice overexpressing human renin and angiotensinogen. (Baumbach GL, Sigmund CD, Faraci FM) Hypertension 2003 Jan;41(1):50-5       90 Citations
1Pharmacological studies on internal mammary artery bypass grafts. Action of endogenous and exogenous vasodilators and vasoconstrictors. (Evora PR, Pearson PJ, Discigil B, Oeltjen MR, Schaff HV) J Cardiovasc Surg (Torino) 2002 Dec;43(6):761-71       10 Citations
1Increased superoxide and vascular dysfunction in CuZnSOD-deficient mice. (Didion SP, Ryan MJ, Didion LA, Fegan PE, Sigmund CD, Faraci FM) Circ Res 2002 Nov 15;91(10):938-44       206 Citations
1Stent implantation alters coronary artery hemodynamics and wall shear stress during maximal vasodilation. (LaDisa JF Jr, Hettrick DA, Olson LE, Guler I, Gross ER, Kress TT, Kersten JR, Warltier DC, Pagel PS) J Appl Physiol (1985) 2002 Dec;93(6):1939-46       58 Citations
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1Comparison of vasodilatory properties of 14,15-EET analogs: structural requirements for dilation. (Falck JR, Krishna UM, Reddy YK, Kumar PS, Reddy KM, Hittner SB, Deeter C, Sharma KK, Gauthier KM, Campbell WB) Am J Physiol Heart Circ Physiol 2003 Jan;284(1):H337-49       80 Citations
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1A genomic-systems biology map for cardiovascular function. (Stoll M, Cowley AW Jr, Tonellato PJ, Greene AS, Kaldunski ML, Roman RJ, Dumas P, Schork NJ, Wang Z, Jacob HJ) Science 2001 Nov 23;294(5547):1723-6       152 Citations
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1Ceramide reduces endothelium-dependent vasodilation by increasing superoxide production in small bovine coronary arteries. (Zhang DX, Zou AP, Li PL) Circ Res 2001 Apr 27;88(8):824-31       72 Citations
2Endothelium-independent, ouabain-sensitive relaxation of bovine coronary arteries by EETs. (Pratt PF, Li P, Hillard CJ, Kurian J, Campbell WB) Am J Physiol Heart Circ Physiol 2001 Mar;280(3):H1113-21       53 Citations
1Adenosine diphosphate ribose dilates bovine coronary small arteries through apyrase- and 5'-nucleotidase-mediated metabolism. (Zhang DX, Zou AP, Li PL) J Vasc Res 2001;38(1):64-72       14 Citations
1Adenosine and ATP cause nitric oxide-dependent pulmonary vasodilation in fetal lambs. (Konduri GG, Mital S) Biol Neonate 2000 Oct;78(3):220-9       34 Citations
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