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Publications indexed to the term Molecular Structure

FacultyTitle
1A Photoinducible DNA Cross-Linking Agent with Potent Cytotoxicity and Selectivity Toward Triple-Negative Breast Cancer Cell Line. (Zhang Q, Ali T, Ponnamperumage TNF, Lin Z, Setu NI, Awoyera WO, Oddiri RT, Rasmussen AD, Felli MC, Frick DN, Peng X) Chem Res Toxicol 2025 Jan 20;38(1):216-228       1 Citation
3The Synthesis and Anti-Cytomegalovirus Activity of Piperidine-4-Carboxamides. (Guo X, Ghosh AK, Keyes RF, Peterson F, Forman M, Meyers DJ, Arav-Boger R) Viruses 2022 Jan 25;14(2)       2 Citations
1Development of novel phenoxyalkylpiperidines as high-affinity Sigma-1 (σ1) receptor ligands with potent anti-amnesic effect. (Abatematteo FS, Mosier PD, Niso M, Brunetti L, Berardi F, Loiodice F, Contino M, Delprat B, Maurice T, Laghezza A, Abate C) Eur J Med Chem 2022 Jan 15;228:114038       3 Citations
1A3 adenosine receptor agonists containing dopamine moieties for enhanced interspecies affinity. (Tosh DK, Salmaso V, Campbell RG, Rao H, Bitant A, Pottie E, Stove CP, Liu N, Gavrilova O, Gao ZG, Auchampach JA, Jacobson KA) Eur J Med Chem 2022 Jan 15;228:113983       9 Citations
1Experimental and Computational Studies on the Ruthenium-Catalyzed Dehydrative C-H Coupling of Phenols with Aldehydes for the Synthesis of 2-Alkylphenol, Benzofuran, and Xanthene Derivatives. (Pannilawithana N, Pudasaini B, Baik MH, Yi CS) J Am Chem Soc 2021 Aug 25;143(33):13428-13440       22 Citations
1Insight into the Maturation Process of the Nitrile Hydratase Active Site. (Ogutu IRAM, Holz RC, Bennett B) Inorg Chem 2021 Apr 19;60(8):5432-5435       5 Citations
1Chemo-enzymatic synthesis of adenine substituted nicotinic acid adenine dinucleotide phosphate (NAADP) analogs. (Su P, Bretz JD, Gunaratne GS, Marchant JS, Walseth TF, Slama JT) Bioorg Med Chem 2021 Jan 15;30:115901       6 Citations
1The Nontypeable Haemophilus influenzae Major Adhesin Hia Is a Dual-Function Lectin That Binds to Human-Specific Respiratory Tract Sialic Acid Glycan Receptors. (Atack JM, Day CJ, Poole J, Brockman KL, Timms JRL, Winter LE, Haselhorst T, Bakaletz LO, Barenkamp SJ, Jennings MP) mBio 2020 Nov 03;11(6)       13 Citations
1Synthesis and evaluation of 17α-triazolyl and 9α-cyano derivatives of estradiol. (Wetzel EA, Hanson AM, Troutfetter CL, Burkett DJ, Sem DS, Donaldson WA) Bioorg Med Chem 2020 Oct 01;28(19):115670       5 Citations
1Development of activity-based probes for the protein deacylase Sirt1. (Goetz CJ, Sprague DJ, Smith BC) Bioorg Chem 2020 Nov;104:104232       7 Citations
1miRNAs Modulate the Dichotomy of Cisplatin Resistance or Sensitivity in Breast Cancer: An Update of Therapeutic Implications. (Safi A, Bastami M, Delghir S, Ilkhani K, Seif F, Alivand MR) Anticancer Agents Med Chem 2021;21(9):1069-1081       9 Citations
1Boholamide A, an APD-Class, Hypoxia-Selective Cyclodepsipeptide. (Torres JP, Lin Z, Fenton DS, Leavitt LU, Niu C, Lam PY, Robes JM, Peterson RT, Concepcion GP, Haygood MG, Olivera BM, Schmidt EW) J Nat Prod 2020 Apr 24;83(4):1249-1257       12 Citations
1Metalloprotoporphyrin Inhibition of HCV NS3-4A Protease: Structure-Activity Relationships. (Hu K, Zhu Z, Mathahs MM, Tran H, Bommer J, Testa CA, Schmidt WN) Drug Des Devel Ther 2020;14:757-771       4 Citations
1Synthesis and Biological Evaluation of Tryptamines Found in Hallucinogenic Mushrooms: Norbaeocystin, Baeocystin, Norpsilocin, and Aeruginascin. (Sherwood AM, Halberstadt AL, Klein AK, McCorvy JD, Kaylo KW, Kargbo RB, Meisenheimer P) J Nat Prod 2020 Feb 28;83(2):461-467       63 Citations
2An anthrone-based Kv7.2/7.3 channel blocker with improved properties for the investigation of psychiatric and neurodegenerative disorders. (Porter JD, Vivas O, Weaver CD, Alsafran A, DiMilo E, Arnold LA, Dickson EJ, Dockendorff C) Bioorg Med Chem Lett 2019 Dec 01;29(23):126681       6 Citations
1High-affinity sigma-1 (σ1) receptor ligands based on the σ1 antagonist PB212. (Niso M, Mosier PD, Marottoli R, Ferorelli S, Cassano G, Gasparre G, Leopoldo M, Berardi F, Abate C) Future Med Chem 2019 Oct;11(19):2547-2562       6 Citations
1Design of fluorinated cyclopropane derivatives of 2-phenylcyclopropylmethylamine leading to identification of a selective serotonin 2C (5-HT2C) receptor agonist without 5-HT2B agonism. (Zhang G, McCorvy JD, Shen S, Cheng J, Roth BL, Kozikowski AP) Eur J Med Chem 2019 Nov 15;182:111626       8 Citations
1Insights into the catalytic mechanism of a bacterial hydrolytic dehalogenase that degrades the fungicide chlorothalonil. (Yang X, Bennett B, Holz RC) J Biol Chem 2019 Sep 06;294(36):13411-13420       10 Citations
2The parmodulin NRD-21 is an allosteric inhibitor of PAR1 Gq signaling with improved anti-inflammatory activity and stability. (Gandhi DM, Rosas R Jr, Greve E, Kentala K, D-R Diby N, Snyder VA, Stephans A, Yeung THW, Subramaniam S, DiMilo E, Kurtenbach KE, Arnold LA, Weiler H, Dockendorff C) Bioorg Med Chem 2019 Sep 01;27(17):3788-3796       12 Citations
2HPLC-Based Monitoring of Oxidation of Hydroethidine for the Detection of NADPH Oxidase-Derived Superoxide Radical Anion. (Zielonka J, Zielonka M, Kalyanaraman B) Methods Mol Biol 2019;1982:243-258       7 Citations
4High-Throughput Screening of NOX Inhibitors. (Zielonka J, Zielonka M, Cheng G, Hardy M, Kalyanaraman B) Methods Mol Biol 2019;1982:429-446       13 Citations
13-Arylindanones and related compounds as antiproliferative agents against colorectal cancer. (Srivastava A, Ravi K, Fatima K, Maheshwari M, Ashraf R, Hasanain M, Yadav P, Iqbal H, Kumar Y, Luqman S, Chanda D, Khan F, Shanker K, Sarkar J, Negi AS) Chem Biol Drug Des 2019 Sep;94(3):1694-1705       4 Citations
1D2 Dopamine Receptor G Protein-Biased Partial Agonists Based on Cariprazine. (Shen Y, McCorvy JD, Martini ML, Rodriguiz RM, Pogorelov VM, Ward KM, Wetsel WC, Liu J, Roth BL, Jin J) J Med Chem 2019 May 09;62(9):4755-4771       18 Citations
1Design and in Vivo Characterization of A1 Adenosine Receptor Agonists in the Native Ribose and Conformationally Constrained (N)-Methanocarba Series. (Tosh DK, Rao H, Bitant A, Salmaso V, Mannes P, Lieberman DI, Vaughan KL, Mattison JA, Rothwell AC, Auchampach JA, Ciancetta A, Liu N, Cui Z, Gao ZG, Reitman ML, Gavrilova O, Jacobson KA) J Med Chem 2019 Feb 14;62(3):1502-1522       23 Citations
1Novel insights into the dynamics behavior of glucagon-like peptide-1 receptor with its small molecule agonists. (Girdhar K, Dehury B, Kumar Singh M, Daniel VP, Choubey A, Dogra S, Kumar S, Mondal P) J Biomol Struct Dyn 2019 Sep;37(15):3976-3986       33 Citations
1Synthesis and evaluation of 4-cycloheptylphenols as selective Estrogen receptor-β agonists (SERBAs). (Sampathi Perera KLI, Hanson AM, Lindeman S, Imhoff A, Lu X, Sem DS, Donaldson WA) Eur J Med Chem 2018 Sep 05;157:791-804       5 Citations
1Poly(Pentafluorophenyl Methacrylate)-Based Nano-Objects Developed by Photo-PISA as Scaffolds for Post-Polymerization Functionalization. (Couturaud B, Georgiou PG, Varlas S, Jones JR, Arno MC, Foster JC, O'Reilly RK) Macromol Rapid Commun 2019 Jan;40(2):e1800460       51 Citations
1Experimental and Computational Study of the ( Z)-Selective Formation of Trisubstituted Olefins and Benzo-Fused Oxacycles from the Ruthenium-Catalyzed Dehydrative C-H Coupling of Phenols with Ketones. (Lee H, Mane MV, Ryu H, Sahu D, Baik MH, Yi CS) J Am Chem Soc 2018 Aug 15;140(32):10289-10296       27 Citations
1Different Benzodiazepines Bind with Distinct Binding Modes to GABAA Receptors. (Elgarf AA, Siebert DCB, Steudle F, Draxler A, Li G, Huang S, Cook JM, Ernst M, Scholze P) ACS Chem Biol 2018 Aug 17;13(8):2033-2039       30 Citations
1Apelinergic System Structure and Function. (Shin K, Kenward C, Rainey JK) Compr Physiol 2017 Dec 12;8(1):407-450       87 Citations
1Mixed Fluorotryptophan Substitutions at the Same Residue Expand the Versatility of 19 F Protein NMR Spectroscopy. (Kenward C, Shin K, Rainey JK) Chemistry 2018 Mar 07;24(14):3391-3396       17 Citations
1Novel VDR antagonists based on the GW0742 scaffold. (Teske KA, Bogart JW, Arnold LA) Bioorg Med Chem Lett 2018 Feb 01;28(3):351-354       7 Citations
1Total Synthesis of Sarpagine-Related Bioactive Indole Alkaloids. (Rahman MT, Deschamps JR, Imler GH, Cook JM) Chemistry 2018 Feb 16;24(10):2354-2359       26 Citations
1Unusual Double Beckmann Fragmentation Reaction under Physiological Conditions. (Xie LN, Huang CH, Xu D, Li F, Zhu JG, Shen C, Shao B, Gao HY, Kalyanaraman B, Zhu BZ) J Org Chem 2017 Dec 15;82(24):13084-13092       9 Citations
1Synthesis and antiplasmodial activity of novel indoleamide derivatives bearing sulfonamide and triazole pharmacophores. (Devender N, Gunjan S, Tripathi R, Tripathi RP) Eur J Med Chem 2017 May 05;131:171-184       48 Citations
1In silico design of novel probes for the atypical opioid receptor MRGPRX2. (Lansu K, Karpiak J, Liu J, Huang XP, McCorvy JD, Kroeze WK, Che T, Nagase H, Carroll FI, Jin J, Shoichet BK, Roth BL) Nat Chem Biol 2017 May;13(5):529-536       241 Citations
1Tumor-Penetrating Nanoparticles for Enhanced Anticancer Activity of Combined Photodynamic and Hypoxia-Activated Therapy. (Wang Y, Xie Y, Li J, Peng ZH, Sheinin Y, Zhou J, Oupický D) ACS Nano 2017 Feb 28;11(2):2227-2238       442 Citations
1Macrocyclic MEK1/2 inhibitor with efficacy in a mouse model of cardiomyopathy caused by lamin A/C gene mutation. (Wu W, Chordia MD, Hart BP, Kumarasinghe ES, Ji MK, Bhargava A, Lawlor MW, Shin JY, Sera F, Homma S, Muchir A, Khire UR, Worman HJ) Bioorg Med Chem 2017 Feb 01;25(3):1004-1013       21 Citations
2Synthesis and Characterization of a Novel γ-Aminobutyric Acid Type A (GABAA) Receptor Ligand That Combines Outstanding Metabolic Stability, Pharmacokinetics, and Anxiolytic Efficacy. (Poe MM, Methuku KR, Li G, Verma AR, Teske KA, Stafford DC, Arnold LA, Cramer JW, Jones TM, Cerne R, Krambis MJ, Witkin JM, Jambrina E, Rehman S, Ernst M, Cook JM, Schkeryantz JM) J Med Chem 2016 Dec 08;59(23):10800-10806       46 Citations
1Synthesis of Bisindole Alkaloids from the Apocynaceae Which Contain a Macroline or Sarpagine Unit: A Review. (Rahman MT, Tiruveedhula VV, Cook JM) Molecules 2016 Nov 14;21(11)       52 Citations
1Novel symmetrical phenylenediamines as potential anti-hepatitis C virus agents. (Bassetto M, Ferla S, Leyssen P, Neyts J, Yerukhimovich MM, Frick DN, O'Donnell R, Brancale A) Antivir Chem Chemother 2015 Dec;24(5-6):155-160       1 Citation
1Discovery of G Protein-Biased D2 Dopamine Receptor Partial Agonists. (Chen X, McCorvy JD, Fischer MG, Butler KV, Shen Y, Roth BL, Jin J) J Med Chem 2016 Dec 08;59(23):10601-10618       47 Citations
1Design and Discovery of Functionally Selective Serotonin 2C (5-HT2C) Receptor Agonists. (Cheng J, McCorvy JD, Giguere PM, Zhu H, Kenakin T, Roth BL, Kozikowski AP) J Med Chem 2016 Nov 10;59(21):9866-9880       31 Citations
1Superagonist, Full Agonist, Partial Agonist, and Antagonist Actions of Arylguanidines at 5-Hydroxytryptamine-3 (5-HT3) Subunit A Receptors. (Alix K, Khatri S, Mosier PD, Casterlow S, Yan D, Nyce HL, White MM, Schulte MK, Dukat M) ACS Chem Neurosci 2016 Nov 16;7(11):1565-1574       12 Citations
1HPLC-Guided Isolation, Purification and Characterization of Phenylpropanoid and Phenolic Constituents of Nutmeg Kernel (Myristica fragrans). (Chiu S, Wang T, Belski M, Abourashed EA) Nat Prod Commun 2016 Apr;11(4):483-8       28 Citations
2Structure-Based Identification of Novel Ligands Targeting Multiple Sites within a Chemokine-G-Protein-Coupled-Receptor Interface. (Smith EW, Nevins AM, Qiao Z, Liu Y, Getschman AE, Vankayala SL, Kemp MT, Peterson FC, Li R, Volkman BF, Chen Y) J Med Chem 2016 May 12;59(9):4342-51       28 Citations
1Inhibitors for the Vitamin D Receptor-Coregulator Interaction. (Teske KA, Yu O, Arnold LA) Vitam Horm 2016;100:45-82       7 Citations
1Development of a Simple Dipstick Assay for Operational Monitoring of DDT. (Ismail HM, Kumar V, Singh RP, Williams C, Shivam P, Ghosh A, Deb R, Foster GM, Hemingway J, Coleman M, Coleman M, Das P, Paine MJ) PLoS Negl Trop Dis 2016 Jan;10(1):e0004324       11 Citations
1Unveiling the crucial intermediates in androgen production. (Mak PJ, Gregory MC, Denisov IG, Sligar SG, Kincaid JR) Proc Natl Acad Sci U S A 2015 Dec 29;112(52):15856-61       73 Citations
1Potential of Horse Apple Isoflavones in Targeting Inflammation and Tau Protein Fibrillization. (Abourashed EA, Abraha A, Khan SI, McCants T, Awan S) Nat Prod Commun 2015 Sep;10(9):1577-80       7 Citations
1Scope and Mechanistic Analysis for Chemoselective Hydrogenolysis of Carbonyl Compounds Catalyzed by a Cationic Ruthenium Hydride Complex with a Tunable Phenol Ligand. (Kalutharage N, Yi CS) J Am Chem Soc 2015 Sep 02;137(34):11105-14       58 Citations
1Isolation and Pharmacological Evaluation of Minor Cannabinoids from High-Potency Cannabis sativa. (Radwan MM, ElSohly MA, El-Alfy AT, Ahmed SA, Slade D, Husni AS, Manly SP, Wilson L, Seale S, Cutler SJ, Ross SA) J Nat Prod 2015 Jun 26;78(6):1271-6       111 Citations
1Novel Potent Orthosteric Antagonist of ASIC1a Prevents NMDAR-Dependent LTP Induction. (Buta A, Maximyuk O, Kovalskyy D, Sukach V, Vovk M, Ievglevskyi O, Isaeva E, Isaev D, Savotchenko A, Krishtal O) J Med Chem 2015 Jun 11;58(11):4449-61       39 Citations
1Chemoselective formation of unsymmetrically substituted ethers from catalytic reductive coupling of aldehydes and ketones with alcohols in aqueous solution. (Kalutharage N, Yi CS) Org Lett 2015 Apr 03;17(7):1778-81       31 Citations
1Adipostatins A-D from Streptomyces sp. 4875 inhibiting Brugia malayi asparaginyl-tRNA synthetase and killing adult Brugia malayi parasites. (Rateb ME, Yang D, Vodanovic-Jankovic S, Yu Z, Kron MA, Shen B) J Antibiot (Tokyo) 2015 Aug;68(8):540-2       12 Citations
1Glucosidase II and MRH-domain containing proteins in the secretory pathway. (D'Alessio C, Dahms NM) Curr Protein Pept Sci 2015;16(1):31-48       27 Citations
1Steric parameters, molecular modeling and hydropathic interaction analysis of the pharmacology of para-substituted methcathinone analogues. (Sakloth F, Kolanos R, Mosier PD, Bonano JS, Banks ML, Partilla JS, Baumann MH, Negus SS, Glennon RA) Br J Pharmacol 2015 May;172(9):2210-8       38 Citations
1Resonance Raman spectroscopy reveals pH-dependent active site structural changes of lactoperoxidase compound 0 and its ferryl heme O-O bond cleavage products. (Mak PJ, Thammawichai W, Wiedenhoeft D, Kincaid JR) J Am Chem Soc 2015 Jan 14;137(1):349-61       35 Citations
1General strategy for synthesis of C-19 methyl-substituted sarpagine/macroline/ajmaline indole alkaloids including total synthesis of 19(S),20(R)-dihydroperaksine, 19(S),20(R)-dihydroperaksine-17-al, and peraksine. (Edwankar RV, Edwankar CR, Deschamps JR, Cook JM) J Org Chem 2014 Nov 07;79(21):10030-48       32 Citations
1Membrane dipole modifiers modulate single-length nystatin channels via reducing elastic stress in the vicinity of the lipid mouth of a pore. (Chulkov EG, Schagina LV, Ostroumova OS) Biochim Biophys Acta 2015 Jan;1848(1 Pt A):192-9       22 Citations
1Homoleptic nickel(II) complexes of redox-tunable pincer-type ligands. (Hewage JS, Wanniarachchi S, Morin TJ, Liddle BJ, Banaszynski M, Lindeman SV, Bennett B, Gardinier JR) Inorg Chem 2014 Oct 06;53(19):10070-84       20 Citations
1Water-stable manganese(IV) complex of a N2O4-donor non-Schiff-base ligand: synthesis, structure, and multifrequency high-field electron paramagnetic resonance studies. (Dolai M, Amjad A, Debnath M, van Tol J, del Barco E, Ali M) Inorg Chem 2014 Jun 02;53(11):5423-8       15 Citations
1Synthesis and spin-trapping properties of a trifluoromethyl analogue of DMPO: 5-methyl-5-trifluoromethyl-1-pyrroline N-oxide (5-TFDMPO). (Karoui H, Nsanzumuhire C, Le Moigne F, Hardy M, Siri D, Derat E, Rockenbauer A, Ouari O, Tordo P) Chemistry 2014 Apr 01;20(14):4064-71       13 Citations
1Design and synthesis of novel antimicrobials with activity against Gram-positive bacteria and mycobacterial species, including M. tuberculosis. (Tiruveedhula VV, Witzigmann CM, Verma R, Kabir MS, Rott M, Schwan WR, Medina-Bielski S, Lane M, Close W, Polanowski RL, Sherman D, Monte A, Deschamps JR, Cook JM) Bioorg Med Chem 2013 Dec 15;21(24):7830-40       13 Citations
1Anion release and uptake kinetics: structural changes of layered 2-dimensional ZnNiHN upon uptake of acetate and chlorinated acetate anions. (Machingauta C, Hossenlopp JM) J Colloid Interface Sci 2013 Dec 01;411:129-37       4 Citations
2Protein structure in context: the molecular landscape of angiogenesis. (Span EA, Goodsell DS, Ramchandran R, Franzen MA, Herman T, Sem DS) Biochem Mol Biol Educ 2013;41(4):213-23       7 Citations
2Activation of dimeric ABA receptors elicits guard cell closure, ABA-regulated gene expression, and drought tolerance. (Okamoto M, Peterson FC, Defries A, Park SY, Endo A, Nambara E, Volkman BF, Cutler SR) Proc Natl Acad Sci U S A 2013 Jul 16;110(29):12132-7       272 Citations
2Reaction between peroxynitrite and triphenylphosphonium-substituted arylboronic acid isomers: identification of diagnostic marker products and biological implications. (Sikora A, Zielonka J, Adamus J, Debski D, Dybala-Defratyka A, Michalowski B, Joseph J, Hartley RC, Murphy MP, Kalyanaraman B) Chem Res Toxicol 2013 Jun 17;26(6):856-67       43 Citations
1Properties of membranes derived from the total lipids extracted from the human lens cortex and nucleus. (Mainali L, Raguz M, O'Brien WJ, Subczynski WK) Biochim Biophys Acta 2013 Jun;1828(6):1432-40       53 Citations
1Potent methyl oxidation of 5-methyl-2'-deoxycytidine by halogenated quinoid carcinogens and hydrogen peroxide via a metal-independent mechanism. (Shao J, Huang CH, Kalyanaraman B, Zhu BZ) Free Radic Biol Med 2013 Jul;60:177-82       47 Citations
1Porcine sperm bind to specific 6-sialylated biantennary glycans to form the oviduct reservoir. (Kadirvel G, Machado SA, Korneli C, Collins E, Miller P, Bess KN, Aoki K, Tiemeyer M, Bovin N, Miller DJ) Biol Reprod 2012 Jun;87(6):147       63 Citations
2Molecular description of the propagation of chirality from molecules to complex systems: different mechanisms controlled by hydrophobic interactions. (Marinelli F, Sorrenti A, Corvaglia V, Leone V, Mancini G) Chemistry 2012 Nov 12;18(46):14680-8       19 Citations
1Unprecedented hydroxyl radical-dependent two-step chemiluminescence production by polyhalogenated quinoid carcinogens and H2O2. (Zhu BZ, Mao L, Huang CH, Qin H, Fan RM, Kalyanaraman B, Zhu JG) Proc Natl Acad Sci U S A 2012 Oct 02;109(40):16046-51       107 Citations
1New WS9326A congeners from Streptomyces sp. 9078 inhibiting Brugia malayi asparaginyl-tRNA synthetase. (Yu Z, Vodanovic-Jankovic S, Kron M, Shen B) Org Lett 2012 Sep 21;14(18):4946-9       55 Citations
1Structure-based ligand discovery for the protein-protein interface of chemokine receptor CXCR4. (Mysinger MM, Weiss DR, Ziarek JJ, Gravel S, Doak AK, Karpiak J, Heveker N, Shoichet BK, Volkman BF) Proc Natl Acad Sci U S A 2012 Apr 03;109(14):5517-22       129 Citations
2Nature against depression. (El-Alfy AT, Abourashed EA, Matsumoto RR) Curr Med Chem 2012;19(14):2229-41       19 Citations
1Structure determination of a membrane protein in proteoliposomes. (Das BB, Nothnagel HJ, Lu GJ, Son WS, Tian Y, Marassi FM, Opella SJ) J Am Chem Soc 2012 Feb 01;134(4):2047-56       81 Citations
1A new highly selective fluorescent K+ sensor. (Zhou X, Su F, Tian Y, Youngbull C, Johnson RH, Meldrum DR) J Am Chem Soc 2011 Nov 23;133(46):18530-3       157 Citations
1Oxidative chemistry of fluorescent dyes: implications in the detection of reactive oxygen and nitrogen species. (Kalyanaraman B) Biochem Soc Trans 2011 Oct;39(5):1221-5       67 Citations
1Structural basis for human NADPH-cytochrome P450 oxidoreductase deficiency. (Xia C, Panda SP, Marohnic CC, Martásek P, Masters BS, Kim JJ) Proc Natl Acad Sci U S A 2011 Aug 16;108(33):13486-91       104 Citations
1A chemical probe selectively inhibits G9a and GLP methyltransferase activity in cells. (Vedadi M, Barsyte-Lovejoy D, Liu F, Rival-Gervier S, Allali-Hassani A, Labrie V, Wigle TJ, Dimaggio PA, Wasney GA, Siarheyeva A, Dong A, Tempel W, Wang SC, Chen X, Chau I, Mangano TJ, Huang XP, Simpson CD, Pattenden SG, Norris JL, Kireev DB, Tripathy A, Edwards A, Roth BL, Janzen WP, Garcia BA, Petronis A, Ellis J, Brown PJ, Frye SV, Arrowsmith CH, Jin J) Nat Chem Biol 2011 Jul 10;7(8):566-74       467 Citations
1Pyrazolyl methyls prescribe the electronic properties of iron(II) tetra(pyrazolyl)lutidine chloride complexes. (Morin TJ, Wanniarachchi S, Gwengo C, Makura V, Tatlock HM, Lindeman SV, Bennett B, Long GJ, Grandjean F, Gardinier JR) Dalton Trans 2011 Aug 21;40(31):8024-34       16 Citations
1Antimycobacterial activity of ferutinin alone and in combination with antitubercular drugs against a rapidly growing surrogate of Mycobacterium tuberculosis. (Abourashed EA, Galal AM, Shibl AM) Nat Prod Res 2011 Jul;25(12):1142-9       16 Citations
1Tirandamycins from Streptomyces sp. 17944 inhibiting the parasite Brugia malayi asparagine tRNA synthetase. (Yu Z, Vodanovic-Jankovic S, Ledeboer N, Huang SX, Rajski SR, Kron M, Shen B) Org Lett 2011 Apr 15;13(8):2034-7       56 Citations
1Performance evaluation of PAMAM dendrimer based simvastatin formulations. (Kulhari H, Pooja D, Prajapati SK, Chauhan AS) Int J Pharm 2011 Feb 28;405(1-2):203-9       105 Citations
1Crystal growth inhibitors for the prevention of L-cystine kidney stones through molecular design. (Rimer JD, An Z, Zhu Z, Lee MH, Goldfarb DS, Wesson JA, Ward MD) Science 2010 Oct 15;330(6002):337-341       225 Citations
1Isolation and characterization of dendrimers with precise numbers of functional groups. (Mullen DG, Borgmeier EL, Desai AM, van Dongen MA, Barash M, Cheng XM, Baker JR Jr, Banaszak Holl MM) Chemistry 2010 Sep 17;16(35):10675-8       35 Citations
1De novo synthesis of polyhydroxyl aminocyclohexanes. (Sar A, Lindeman S, Donaldson WA) Org Biomol Chem 2010 Sep 07;8(17):3908-17       9 Citations
1Regioselective formation of alpha-vinylpyrroles from the ruthenium-catalyzed coupling reaction of pyrroles and terminal alkynes involving C-H bond activation. (Gao R, Yi CS) J Org Chem 2010 May 07;75(9):3144-6       40 Citations
2Chirality holds the key for potent inhibition of the botulinum neurotoxin serotype a protease. (Stowe GN, Silhár P, Hixon MS, Silvaggi NR, Allen KN, Moe ST, Jacobson AR, Barbieri JT, Janda KD) Org Lett 2010 Feb 19;12(4):756-9       32 Citations
1Structure-based drug design and modern medicine. (Vijayakrishnan R) J Postgrad Med 2009;55(4):301-4       39 Citations
1Inhibition of acid, alkaline, and tyrosine (PTP1B) phosphatases by novel vanadium complexes. (McLauchlan CC, Hooker JD, Jones MA, Dymon Z, Backhus EA, Greiner BA, Dorner NA, Youkhana MA, Manus LM) J Inorg Biochem 2010 Mar;104(3):274-81       67 Citations
1Structure-based design, synthesis, and biochemical and pharmacological characterization of novel salvinorin A analogues as active state probes of the kappa-opioid receptor. (Yan F, Bikbulatov RV, Mocanu V, Dicheva N, Parker CE, Wetsel WC, Mosier PD, Westkaemper RB, Allen JA, Zjawiony JK, Roth BL) Biochemistry 2009 Jul 28;48(29):6898-908       73 Citations
1Metal-independent decomposition of hydroperoxides by halogenated quinones: detection and identification of a quinone ketoxy radical. (Zhu BZ, Shan GQ, Huang CH, Kalyanaraman B, Mao L, Du YG) Proc Natl Acad Sci U S A 2009 Jul 14;106(28):11466-71       96 Citations
1Discovery of potent and practical antiangiogenic agents inspired by cortistatin A. (Czakó B, Kürti L, Mammoto A, Ingber DE, Corey EJ) J Am Chem Soc 2009 Jul 01;131(25):9014-9       56 Citations
1Toward the three-dimensional structure and lysophosphatidic acid binding characteristics of the LPA(4)/p2y(9)/GPR23 receptor: a homology modeling study. (Li G, Mosier PD, Fang X, Zhang Y) J Mol Graph Model 2009 Aug;28(1):70-9       8 Citations
1Unexpected in vivo anti-inflammatory activity observed for simple, surface functionalized poly(amidoamine) dendrimers. (Chauhan AS, Diwan PV, Jain NK, Tomalia DA) Biomacromolecules 2009 May 11;10(5):1195-202       177 Citations
1Fuel specificity of the hepatitis C virus NS3 helicase. (Belon CA, Frick DN) J Mol Biol 2009 May 15;388(4):851-64       21 Citations
1Bicelles: A natural 'molecular goniometer' for structural, dynamical and topological studies of molecules in membranes. (Diller A, Loudet C, Aussenac F, Raffard G, Fournier S, Laguerre M, Grélard A, Opella SJ, Marassi FM, Dufourc EJ) Biochimie 2009 Jun;91(6):744-51       99 Citations
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1Potential modes of interaction of 9-aminomethyl-9,10-dihydroanthracene (AMDA) derivatives with the 5-HT2A receptor: a ligand structure-affinity relationship, receptor mutagenesis and receptor modeling investigation. (Runyon SP, Mosier PD, Roth BL, Glennon RA, Westkaemper RB) J Med Chem 2008 Nov 13;51(21):6808-28       37 Citations
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3Detection, characterization, and decay kinetics of ROS and thiyl adducts of mito-DEPMPO spin trap. (Hardy M, Rockenbauer A, Vásquez-Vivar J, Felix C, Lopez M, Srinivasan S, Avadhani N, Tordo P, Kalyanaraman B) Chem Res Toxicol 2007 Jul;20(7):1053-60       61 Citations
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1Physical properties of the lipid bilayer membrane made of calf lens lipids: EPR spin labeling studies. (Widomska J, Raguz M, Dillon J, Gaillard ER, Subczynski WK) Biochim Biophys Acta 2007 Jun;1768(6):1454-65       53 Citations
1Characterization of 14,15-epoxyeicosatrienoyl-sulfonamides as 14,15-epoxyeicosatrienoic acid agonists: use for studies of metabolism and ligand binding. (Yang W, Holmes BB, Gopal VR, Kishore RV, Sangras B, Yi XY, Falck JR, Campbell WB) J Pharmacol Exp Ther 2007 Jun;321(3):1023-31       43 Citations
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1Synthesis of highly substituted dibenzo[b,f]azocines and their evaluation as protein kinase inhibitors. (Arnold LA, Kiplin Guy R) Bioorg Med Chem Lett 2006 Oct 15;16(20):5360-3       18 Citations
1Low frequency resonance Raman spectra of isolated alpha and beta subunits of hemoglobin and their deuterated analogues. (Podstawka E, Mak PJ, Kincaid JR, Proniewicz LM) Biopolymers 2006 Dec 05;83(5):455-66       18 Citations
1Anthralin: primary products of its redox reactions. (Czerwinska M, Sikora A, Szajerski P, Zielonka J, Adamus J, Marcinek A, Piech K, Bednarek P, Bally T) J Org Chem 2006 Jul 07;71(14):5312-9       19 Citations
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1Kinetic and spectroscopic characterization of the E134A- and E134D-altered dapE-encoded N-succinyl-L,L-diaminopimelic acid desuccinylase from Haemophilus influenzae. (Davis R, Bienvenue D, Swierczek SI, Gilner DM, Rajagopal L, Bennett B, Holz RC) J Biol Inorg Chem 2006 Mar;11(2):206-16       25 Citations
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1A novel family of atherogenic oxidized phospholipids promotes macrophage foam cell formation via the scavenger receptor CD36 and is enriched in atherosclerotic lesions. (Podrez EA, Poliakov E, Shen Z, Zhang R, Deng Y, Sun M, Finton PJ, Shan L, Febbraio M, Hajjar DP, Silverstein RL, Hoff HF, Salomon RG, Hazen SL) J Biol Chem 2002 Oct 11;277(41):38517-23       362 Citations
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