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1 | Structure of the human histamine H1 receptor complex with doxepin. (Shimamura T, Shiroishi M, Weyand S, Tsujimoto H, Winter G, Katritch V, Abagyan R, Cherezov V, Liu W, Han GW, Kobayashi T, Stevens RC, Iwata S) Nature 2011 Jun 22;475(7354):65-70 708 Citations |
1 | Extracellular disulfide bonds support scavenger receptor class B type I-mediated cholesterol transport. (Papale GA, Hanson PJ, Sahoo D) Biochemistry 2011 Jul 19;50(28):6245-54 26 Citations |
1 | Free energies for coarse-grained proteins by integrating multibody statistical contact potentials with entropies from elastic network models. (Zimmermann MT, Leelananda SP, Gniewek P, Feng Y, Jernigan RL, Kloczkowski A) J Struct Funct Genomics 2011 Jul;12(2):137-47 16 Citations |
1 | Unique ganglioside binding by botulinum neurotoxins C and D-SA. (Kroken AR, Karalewitz AP, Fu Z, Baldwin MR, Kim JJ, Barbieri JT) FEBS J 2011 Dec;278(23):4486-96 23 Citations |
1 | Interaction of nitric oxide with catalase: structural and kinetic analysis. (Purwar N, McGarry JM, Kostera J, Pacheco AA, Schmidt M) Biochemistry 2011 May 31;50(21):4491-503 73 Citations |
1 | Defining CYP3A4 structural responses to substrate binding. Raman spectroscopic studies of a nanodisc-incorporated mammalian cytochrome P450. (Mak PJ, Denisov IG, Grinkova YV, Sligar SG, Kincaid JR) J Am Chem Soc 2011 Feb 09;133(5):1357-66 45 Citations |
1 | Structure of the human dopamine D3 receptor in complex with a D2/D3 selective antagonist. (Chien EY, Liu W, Zhao Q, Katritch V, Han GW, Hanson MA, Shi L, Newman AH, Javitch JA, Cherezov V, Stevens RC) Science 2010 Nov 19;330(6007):1091-5 1015 Citations |
1 | Structural biology: On stress and pressure. (Sigmund CD) Nature 2010 Nov 04;468(7320):46-7 7 Citations |
1 | Structures of the CXCR4 chemokine GPCR with small-molecule and cyclic peptide antagonists. (Wu B, Chien EY, Mol CD, Fenalti G, Liu W, Katritch V, Abagyan R, Brooun A, Wells P, Bi FC, Hamel DJ, Kuhn P, Handel TM, Cherezov V, Stevens RC) Science 2010 Nov 19;330(6007):1066-71 1555 Citations |
1 | Closed headpiece of integrin αIIbβ3 and its complex with an αIIbβ3-specific antagonist that does not induce opening. (Zhu J, Zhu J, Negri A, Provasi D, Filizola M, Coller BS, Springer TA) Blood 2010 Dec 02;116(23):5050-9 100 Citations |
1 | Conformation of dimeric apolipoprotein A-I milano on recombinant lipoprotein particles. (Bhat S, Sorci-Thomas MG, Calabresi L, Samuel MP, Thomas MJ) Biochemistry 2010 Jun 29;49(25):5213-24 17 Citations |
1 | Structural analysis of botulinum neurotoxin type G receptor binding . (Schmitt J, Karalewitz A, Benefield DA, Mushrush DJ, Pruitt RN, Spiller BW, Barbieri JT, Lacy DB) Biochemistry 2010 Jun 29;49(25):5200-5 33 Citations |
1 | Toxins from bacteria. (Henkel JS, Baldwin MR, Barbieri JT) EXS 2010;100:1-29 80 Citations |
1 | Mycobacterium tuberculosis Rv0899 adopts a mixed alpha/beta-structure and does not form a transmembrane beta-barrel. (Teriete P, Yao Y, Kolodzik A, Yu J, Song H, Niederweis M, Marassi FM) Biochemistry 2010 Apr 06;49(13):2768-77 25 Citations |
2 | Targeting biomolecular flexibility with metadynamics. (Leone V, Marinelli F, Carloni P, Parrinello M) Curr Opin Struct Biol 2010 Apr;20(2):148-54 126 Citations |
1 | Defining the structural consequences of mechanism-based inactivation of mammalian cytochrome P450 2B4 using resonance Raman spectroscopy. (Mak PJ, Zhang H, Hollenberg PF, Kincaid JR) J Am Chem Soc 2010 Feb 10;132(5):1494-5 15 Citations |
2 | Rapid, robotic, small-scale protein production for NMR screening and structure determination. (Jensen DR, Woytovich C, Li M, Duvnjak P, Cassidy MS, Frederick RO, Bergeman LF, Peterson FC, Volkman BF) Protein Sci 2010 Mar;19(3):570-8 8 Citations |
1 | Identification of a functionally important loop in Salmonella typhimurium ArnT. (Impellitteri NA, Merten JA, Bretscher LE, Klug CS) Biochemistry 2010 Jan 12;49(1):29-35 8 Citations |
2 | Intermonomer interactions are essential for lysosomal enzyme binding by the cation-dependent mannose 6-phosphate receptor. (Olson LJ, Sun G, Bohnsack RN, Peterson FC, Dahms NM, Kim JJ) Biochemistry 2010 Jan 12;49(1):236-46 8 Citations |
1 | A synergistic small-molecule combination directly eradicates diverse prion strain structures. (Roberts BE, Duennwald ML, Wang H, Chung C, Lopreiato NP, Sweeny EA, Knight MN, Shorter J) Nat Chem Biol 2009 Dec;5(12):936-46 85 Citations |
1 | Carbohydrate recognition by the mannose-6-phosphate receptors. (Kim JJ, Olson LJ, Dahms NM) Curr Opin Struct Biol 2009 Oct;19(5):534-42 64 Citations |
1 | Effects of PKA phosphorylation on the conformation of the Na,K-ATPase regulatory protein FXYD1. (Teriete P, Thai K, Choi J, Marassi FM) Biochim Biophys Acta 2009 Nov;1788(11):2462-70 20 Citations |
1 | Dopamine-induced conformational changes in alpha-synuclein. (Outeiro TF, Klucken J, Bercury K, Tetzlaff J, Putcha P, Oliveira LM, Quintas A, McLean PJ, Hyman BT) PLoS One 2009 Sep 04;4(9):e6906 59 Citations |
1 | Synthesis, structure-affinity relationships, and modeling of AMDA analogs at 5-HT2A and H1 receptors: structural factors contributing to selectivity. (Shah JR, Mosier PD, Roth BL, Kellogg GE, Westkaemper RB) Bioorg Med Chem 2009 Sep 15;17(18):6496-504 21 Citations |
1 | Substrate binding mechanism of HIV-1 protease from explicit-solvent atomistic simulations. (Pietrucci F, Marinelli F, Carloni P, Laio A) J Am Chem Soc 2009 Aug 26;131(33):11811-8 129 Citations |
1 | Inhibition of a viral enzyme by a small-molecule dimer disruptor. (Shahian T, Lee GM, Lazic A, Arnold LA, Velusamy P, Roels CM, Guy RK, Craik CS) Nat Chem Biol 2009 Sep;5(9):640-6 72 Citations |
1 | Focus on molecules: maspin. (Narayan M, Twining S) Exp Eye Res 2010 Jan;90(1):2-3 12 Citations |
1 | Functional role for the conformationally mobile phenylalanine 223 in the reaction of methylenetetrahydrofolate reductase from Escherichia coli. (Lee MN, Takawira D, Nikolova AP, Ballou DP, Furtado VC, Phung NL, Still BR, Thorstad MK, Tanner JJ, Trimmer EE) Biochemistry 2009 Aug 18;48(32):7673-85 17 Citations |
2 | Chapter 3. Lymphotactin structural dynamics. (Volkman BF, Liu TY, Peterson FC) Methods Enzymol 2009;461:51-70 26 Citations |
1 | Glycosylated SV2 and gangliosides as dual receptors for botulinum neurotoxin serotype F. (Fu Z, Chen C, Barbieri JT, Kim JJ, Baldwin MR) Biochemistry 2009 Jun 23;48(24):5631-41 131 Citations |
2 | Structures of two Arabidopsis thaliana major latex proteins represent novel helix-grip folds. (Lytle BL, Song J, de la Cruz NB, Peterson FC, Johnson KA, Bingman CA, Phillips GN Jr, Volkman BF) Proteins 2009 Jul;76(1):237-43 68 Citations |
1 | The major human pregnane X receptor (PXR) splice variant, PXR.2, exhibits significantly diminished ligand-activated transcriptional regulation. (Lin YS, Yasuda K, Assem M, Cline C, Barber J, Li CW, Kholodovych V, Ai N, Chen JD, Welsh WJ, Ekins S, Schuetz EG) Drug Metab Dispos 2009 Jun;37(6):1295-304 35 Citations |
1 | Exploring the folding free energy landscape of insulin using bias exchange metadynamics. (Todorova N, Marinelli F, Piana S, Yarovsky I) J Phys Chem B 2009 Mar 19;113(11):3556-64 42 Citations |
1 | The Center for Eukaryotic Structural Genomics. (Markley JL, Aceti DJ, Bingman CA, Fox BG, Frederick RO, Makino S, Nichols KW, Phillips GN Jr, Primm JG, Sahu SC, Vojtik FC, Volkman BF, Wrobel RL, Zolnai Z) J Struct Funct Genomics 2009 Apr;10(2):165-79 23 Citations |
1 | Pharmacological manipulation of the RAR/RXR signaling pathway maintains the repopulating capacity of hematopoietic stem cells in culture. (Safi R, Muramoto GG, Salter AB, Meadows S, Himburg H, Russell L, Daher P, Doan P, Leibowitz MD, Chao NJ, McDonnell DP, Chute JP) Mol Endocrinol 2009 Feb;23(2):188-201 22 Citations |
1 | Murine NKG2D ligands: "double, double toil and trouble". (Samarakoon A, Chu H, Malarkannan S) Mol Immunol 2009 Mar;46(6):1011-9 38 Citations |
1 | Mapping glycans onto specific N-linked glycosylation sites of Pyrus communis PGIP redefines the interface for EPG-PGIP interactions. (Lim JM, Aoki K, Angel P, Garrison D, King D, Tiemeyer M, Bergmann C, Wells L) J Proteome Res 2009 Feb;8(2):673-80 20 Citations |
2 | HLA-DM mediates epitope selection by a "compare-exchange" mechanism when a potential peptide pool is available. (Ferrante A, Anderson MW, Klug CS, Gorski J) PLoS One 2008;3(11):e3722 28 Citations |
2 | Structural basis of CXCR4 sulfotyrosine recognition by the chemokine SDF-1/CXCL12. (Veldkamp CT, Seibert C, Peterson FC, De la Cruz NB, Haugner JC 3rd, Basnet H, Sakmar TP, Volkman BF) Sci Signal 2008 Sep 16;1(37):ra4 261 Citations |
1 | Kinetic and product distribution analysis of NO* reductase activity in Nitrosomonas europaea hydroxylamine oxidoreductase. (Kostera J, Youngblut MD, Slosarczyk JM, Pacheco AA) J Biol Inorg Chem 2008 Sep;13(7):1073-83 46 Citations |
1 | A model for the solution structure of the rod arrestin tetramer. (Hanson SM, Dawson ES, Francis DJ, Van Eps N, Klug CS, Hubbell WL, Meiler J, Gurevich VV) Structure 2008 Jun;16(6):924-34 67 Citations |
1 | Conformational changes in the metallo-beta-lactamase ImiS during the catalytic reaction: an EPR spectrokinetic study of Co(II)-spin label interactions. (Sharma N, Hu Z, Crowder MW, Bennett B) J Am Chem Soc 2008 Jul 02;130(26):8215-22 18 Citations |
1 | Orientation of the Escherichia coli outer membrane protein OmpX in phospholipid bilayer membranes determined by solid-State NMR. (Mahalakshmi R, Marassi FM) Biochemistry 2008 Jun 24;47(25):6531-8 48 Citations |
1 | Three-dimensional models of HDL apoA-I: implications for its assembly and function. (Thomas MJ, Bhat S, Sorci-Thomas MG) J Lipid Res 2008 Sep;49(9):1875-83 95 Citations |
1 | Catalytic features of the botulinum neurotoxin A light chain revealed by high resolution structure of an inhibitory peptide complex. (Silvaggi NR, Wilson D, Tzipori S, Allen KN) Biochemistry 2008 May 27;47(21):5736-45 55 Citations |
1 | Using structural analysis to generate parasite-selective monoclonal antibodies. (Kron MA, Cichanowicz S, Hendrick A, Liu A, Leykam J, Kuhn LA) Protein Sci 2008 Jun;17(6):983-9 4 Citations |
1 | Structural characterization of the transmembrane domain from subunit e of yeast F1Fo-ATP synthase: a helical GXXXG motif located just under the micelle surface. (Yao H, Stuart RA, Cai S, Sem DS) Biochemistry 2008 Feb 19;47(7):1910-7 10 Citations |
1 | CD36-TSP-HRGP interactions in the regulation of angiogenesis. (Silverstein RL, Febbraio M) Curr Pharm Des 2007;13(35):3559-67 37 Citations |
1 | Galpha-subunits differentially alter the conformation and agonist affinity of kappa-opioid receptors. (Yan F, Mosier PD, Westkaemper RB, Roth BL) Biochemistry 2008 Feb 12;47(6):1567-78 49 Citations |
1 | Binding of serotonin and N1-benzenesulfonyltryptamine-related analogs at human 5-HT6 serotonin receptors: receptor modeling studies. (Dukat M, Mosier PD, Kolanos R, Roth BL, Glennon RA) J Med Chem 2008 Feb 14;51(3):603-11 36 Citations |
1 | Structure of the dual enzyme Ire1 reveals the basis for catalysis and regulation in nonconventional RNA splicing. (Lee KP, Dey M, Neculai D, Cao C, Dever TE, Sicheri F) Cell 2008 Jan 11;132(1):89-100 296 Citations |
1 | Membrane orientation of the Na,K-ATPase regulatory membrane protein CHIF determined by solid-state NMR. (Franzin CM, Teriete P, Marassi FM) Magn Reson Chem 2007 Dec;45 Suppl 1(Suppl 1):S192-7 3 Citations |
1 | Predicting the effect of a point mutation on a protein fold: the villin and advillin headpieces and their Pro62Ala mutants. (Piana S, Laio A, Marinelli F, Van Troys M, Bourry D, Ampe C, Martins JC) J Mol Biol 2008 Jan 11;375(2):460-70 44 Citations |
1 | Interaction between the androgen receptor and a segment of its corepressor SHP. (Jouravel N, Sablin E, Arnold LA, Guy RK, Fletterick RJ) Acta Crystallogr D Biol Crystallogr 2007 Nov;63(Pt 11):1198-200 20 Citations |
1 | Apical membrane targeting and trafficking of the human proton-coupled transporter in polarized epithelia. (Subramanian VS, Marchant JS, Said HM) Am J Physiol Cell Physiol 2008 Jan;294(1):C233-40 41 Citations |
1 | Mapping the specific cytoprotective interaction of humanin with the pro-apoptotic protein bid. (Choi J, Zhai D, Zhou X, Satterthwait A, Reed JC, Marassi FM) Chem Biol Drug Des 2007 Nov;70(5):383-92 18 Citations |
1 | Structural basis of disease-causing mutations in hepatocyte nuclear factor 1beta. (Lu P, Rha GB, Chi YI) Biochemistry 2007 Oct 30;46(43):12071-80 36 Citations |
1 | An unusual transduction pathway in human tonic smooth muscle myosin. (Halstead MF, Ajtai K, Penheiter AR, Spencer JD, Zheng Y, Morrison EA, Burghardt TP) Biophys J 2007 Nov 15;93(10):3555-66 2 Citations |
1 | Modified active site coordination in a clinical mutant of sulfite oxidase. (Doonan CJ, Wilson HL, Rajagopalan KV, Garrett RM, Bennett B, Prince RC, George GN) J Am Chem Soc 2007 Aug 01;129(30):9421-8 28 Citations |
1 | Structural similarity of a membrane protein in micelles and membranes. (Franzin CM, Teriete P, Marassi FM) J Am Chem Soc 2007 Jul 04;129(26):8078-9 47 Citations |
1 | Conformational adaptation of apolipoprotein A-I to discretely sized phospholipid complexes. (Bhat S, Sorci-Thomas MG, Tuladhar R, Samuel MP, Thomas MJ) Biochemistry 2007 Jul 03;46(26):7811-21 65 Citations |
1 | Double-lanthanide-binding tags for macromolecular crystallographic structure determination. (Silvaggi NR, Martin LJ, Schwalbe H, Imperiali B, Allen KN) J Am Chem Soc 2007 Jun 06;129(22):7114-20 75 Citations |
1 | Arrestin mobilizes signaling proteins to the cytoskeleton and redirects their activity. (Hanson SM, Cleghorn WM, Francis DJ, Vishnivetskiy SA, Raman D, Song X, Nair KS, Slepak VZ, Klug CS, Gurevich VV) J Mol Biol 2007 Apr 27;368(2):375-87 115 Citations |
2 | An engineered second disulfide bond restricts lymphotactin/XCL1 to a chemokine-like conformation with XCR1 agonist activity. (Tuinstra RL, Peterson FC, Elgin ES, Pelzek AJ, Volkman BF) Biochemistry 2007 Mar 13;46(10):2564-73 51 Citations |
2 | Multiple WASP-interacting protein recognition motifs are required for a functional interaction with N-WASP. (Peterson FC, Deng Q, Zettl M, Prehoda KE, Lim WA, Way M, Volkman BF) J Biol Chem 2007 Mar 16;282(11):8446-53 42 Citations |
1 | Differential helical orientations among related G protein-coupled receptors provide a novel mechanism for selectivity. Studies with salvinorin A and the kappa-opioid receptor. (Vortherms TA, Mosier PD, Westkaemper RB, Roth BL) J Biol Chem 2007 Feb 02;282(5):3146-56 34 Citations |
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1 | Ca2+-calmodulin and janus kinase 2 are required for activation of sodium-proton exchange by the Gi-coupled 5-hydroxytryptamine 1a receptor. (Turner JH, Garnovskaya MN, Coaxum SD, Vlasova TM, Yakutovich M, Lefler DM, Raymond JR) J Pharmacol Exp Ther 2007 Jan;320(1):314-22 21 Citations |
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1 | Structural characterization of mumps virus fusion protein core. (Liu Y, Xu Y, Lou Z, Zhu J, Hu X, Gao GF, Qiu B, Rao Z, Tien P) Biochem Biophys Res Commun 2006 Sep 29;348(3):916-22 13 Citations |
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1 | Discovering new classes of Brugia malayi asparaginyl-tRNA synthetase inhibitors and relating specificity to conformational change. (Sukuru SC, Crepin T, Milev Y, Marsh LC, Hill JB, Anderson RJ, Morris JC, Rohatgi A, O'Mahony G, Grøtli M, Danel F, Page MG, Härtlein M, Cusack S, Kron MA, Kuhn LA) J Comput Aided Mol Des 2006 Mar;20(3):159-78 45 Citations |
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1 | Visual arrestin binding to microtubules involves a distinct conformational change. (Hanson SM, Francis DJ, Vishnivetskiy SA, Klug CS, Gurevich VV) J Biol Chem 2006 Apr 07;281(14):9765-72 80 Citations |
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2 | 1H, 15N and 13C resonance assignments of the heme-binding protein murine p22HBP. (Dias JS, Macedo AL, Ferreira GC, Jeanty N, Taketani S, Goodfellow BJ, Peterson FC, Volkman BF) J Biomol NMR 2005 Aug;32(4):338 4 Citations |
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1 | Characterization of the antibody response to the receptor binding domain of botulinum neurotoxin serotypes A and E. (Baldwin MR, Tepp WH, Pier CL, Bradshaw M, Ho M, Wilson BA, Fritz RB, Johnson EA, Barbieri JT) Infect Immun 2005 Oct;73(10):6998-7005 58 Citations |
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1 | Specific conformational changes of plasminogen induced by chloride ions, 6-aminohexanoic acid and benzamidine, but not the overall openness of plasminogen regulate, production of biologically active angiostatins. (Warejcka DJ, Twining SS) Biochem J 2005 Dec 15;392(Pt 3):703-12 10 Citations |
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2 | The reaction between nitrite and deoxyhemoglobin. Reassessment of reaction kinetics and stoichiometry. (Huang KT, Keszler A, Patel N, Patel RP, Gladwin MT, Kim-Shapiro DB, Hogg N) J Biol Chem 2005 Sep 02;280(35):31126-31 237 Citations |
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1 | PKR and GCN2 kinases and guanine nucleotide exchange factor eukaryotic translation initiation factor 2B (eIF2B) recognize overlapping surfaces on eIF2alpha. (Dey M, Trieselmann B, Locke EG, Lu J, Cao C, Dar AC, Krishnamoorthy T, Dong J, Sicheri F, Dever TE) Mol Cell Biol 2005 Apr;25(8):3063-75 59 Citations |
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1 | Functional analysis of subunit e of the F1Fo-ATP synthase of the yeast Saccharomyces cerevisiae: importance of the N-terminal membrane anchor region. (Everard-Gigot V, Dunn CD, Dolan BM, Brunner S, Jensen RE, Stuart RA) Eukaryot Cell 2005 Feb;4(2):346-55 54 Citations |
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1 | Crystal structures of complexes between the R61 DD-peptidase and peptidoglycan-mimetic beta-lactams: a non-covalent complex with a "perfect penicillin". (Silvaggi NR, Josephine HR, Kuzin AP, Nagarajan R, Pratt RF, Kelly JA) J Mol Biol 2005 Jan 21;345(3):521-33 50 Citations |
1 | Electrostatic analysis of the hepatitis C virus NS3 helicase reveals both active and allosteric site locations. (Frick DN, Rypma RS, Lam AM, Frenz CM) Nucleic Acids Res 2004;32(18):5519-28 31 Citations |
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1 | Pseudomonas aeruginosa ExoS and ExoT. (Barbieri JT, Sun J) Rev Physiol Biochem Pharmacol 2004;152:79-92 201 Citations |
2 | Solution structure of a ubiquitin-like domain from tubulin-binding cofactor B. (Lytle BL, Peterson FC, Qiu SH, Luo M, Zhao Q, Markley JL, Volkman BF) J Biol Chem 2004 Nov 05;279(45):46787-93 29 Citations |
1 | Biochemical analysis of Angelman syndrome-associated mutations in the E3 ubiquitin ligase E6-associated protein. (Cooper EM, Hudson AW, Amos J, Wagstaff J, Howley PM) J Biol Chem 2004 Sep 24;279(39):41208-17 87 Citations |
1 | Resting state conformation of the MsbA homodimer as studied by site-directed spin labeling. (Buchaklian AH, Funk AL, Klug CS) Biochemistry 2004 Jul 06;43(26):8600-6 33 Citations |
1 | Solution structure of a homodimeric hypothetical protein, At5g22580, a structural genomics target from Arabidopsis thaliana. (Cornilescu G, Cornilescu CC, Zhao Q, Frederick RO, Peterson FC, Thao S, Markley JL) J Biomol NMR 2004 Jul;29(3):387-90 13 Citations |
1 | Toward better antibiotics: crystallographic studies of a novel class of DD-peptidase/beta-lactamase inhibitors. (Silvaggi NR, Kaur K, Adediran SA, Pratt RF, Kelly JA) Biochemistry 2004 Jun 08;43(22):7046-53 18 Citations |
1 | Following the rule: formation of the 6-helix bundle of the fusion core from severe acute respiratory syndrome coronavirus spike protein and identification of potent peptide inhibitors. (Zhu J, Xiao G, Xu Y, Yuan F, Zheng C, Liu Y, Yan H, Cole DK, Bell JI, Rao Z, Tien P, Gao GF) Biochem Biophys Res Commun 2004 Jun 18;319(1):283-8 98 Citations |
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1 | Maltose-binding protein is open in the catalytic transition state for ATP hydrolysis during maltose transport. (Austermuhle MI, Hall JA, Klug CS, Davidson AL) J Biol Chem 2004 Jul 02;279(27):28243-50 64 Citations |
2 | Cdc42 regulates the Par-6 PDZ domain through an allosteric CRIB-PDZ transition. (Peterson FC, Penkert RR, Volkman BF, Prehoda KE) Mol Cell 2004 Mar 12;13(5):665-76 129 Citations |
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1 | Calmodulin interacts with the third intracellular loop of the serotonin 5-hydroxytryptamine1A receptor at two distinct sites: putative role in receptor phosphorylation by protein kinase C. (Turner JH, Gelasco AK, Raymond JR) J Biol Chem 2004 Apr 23;279(17):17027-37 75 Citations |
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