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Publications indexed to the term Protein Conformation

FacultyTitle
2Systematic analysis of the relationship between fold-dependent flexibility and artificial intelligence protein structure prediction. (Haque N, Wagenknecht JB, Ratnasinghe BD, Zimmermann MT) PLoS One 2024;19(11):e0313308    
1A pressure-jump EPR system to monitor millisecond conformational exchange rates of spin-labeled proteins. (Grosskopf JD, Sidabras JW, Altenbach C, Anderson JR, Mett RR, Strangeway RA, Hyde JS, Hubbell WL, Lerch MT) Protein Sci 2024 Dec;33(12):e5220    
1Conformational free-energy landscapes of a Na+/Ca2+ exchanger explain its alternating-access mechanism and functional specificity. (Marinelli F, Faraldo-Gómez JD) Proc Natl Acad Sci U S A 2024 Apr 16;121(16):e2318009121       4 Citations
1Design of stimulus-responsive two-state hinge proteins. (Praetorius F, Leung PJY, Tessmer MH, Broerman A, Demakis C, Dishman AF, Pillai A, Idris A, Juergens D, Dauparas J, Li X, Levine PM, Lamb M, Ballard RK, Gerben SR, Nguyen H, Kang A, Sankaran B, Bera AK, Volkman BF, Nivala J, Stoll S, Baker D) Science 2023 Aug 18;381(6659):754-760       17 Citations
2Calcium-induced environmental adaptability of the blood protein vitronectin. (Tian Y, Shin K, Aleshin AE, Im W, Marassi FM) Biophys J 2022 Oct 18;121(20):3896-3906       3 Citations
3Conformational selection guides β-arrestin recruitment at a biased G protein-coupled receptor. (Kleist AB, Jenjak S, Sente A, Laskowski LJ, Szpakowska M, Calkins MM, Anderson EI, McNally LM, Heukers R, Bobkov V, Peterson FC, Thomas MA, Chevigné A, Smit MJ, McCorvy JD, Babu MM, Volkman BF) Science 2022 Jul 08;377(6602):222-228       16 Citations
1Differential ion dehydration energetics explains selectivity in the non-canonical lysosomal K+ channel TMEM175. (Oh S, Marinelli F, Zhou W, Lee J, Choi HJ, Kim M, Faraldo-Gómez JD, Hite RK) Elife 2022 May 24;11       12 Citations
1Molecular basis for lipid recognition by the prostaglandin D2 receptor CRTH2. (Liu H, Deepak RNVK, Shiriaeva A, Gati C, Batyuk A, Hu H, Weierstall U, Liu W, Wang L, Cherezov V, Fan H, Zhang C) Proc Natl Acad Sci U S A 2021 Aug 10;118(32)       12 Citations
1Protein expression and purification of G-protein coupled receptor kinase 6 (GRK6), toward structure-based drug design and discovery for multiple myeloma. (Olson TL, Zhang S, Labban D, Kaschner E, Aceves M, Iyer S, Meza-Aguilar JD, Zook JD, Chun E, Craciunescu FM, Liu W, Shi CX, Stewart AK, Hansen DT, Meurice N, Fromme P) Protein Expr Purif 2021 Sep;185:105890       4 Citations
2Molecular docking-guided synthesis of NSAID-glucosamine bioconjugates and their evaluation as COX-1/COX-2 inhibitors with potentially reduced gastric toxicity. (Jones Lipinski RA, Thillier Y, Morisseau C, Sebastiano CS Jr, Smith BC, Hall CD, Katritzky AR) Chem Biol Drug Des 2021 Jul;98(1):102-113       10 Citations
1Nucleosome composition regulates the histone H3 tail conformational ensemble and accessibility. (Morrison EA, Baweja L, Poirier MG, Wereszczynski J, Musselman CA) Nucleic Acids Res 2021 May 07;49(8):4750-4767       28 Citations
1Chloride-dependent conformational changes in the GlyT1 glycine transporter. (Zhang YW, Uchendu S, Leone V, Bradshaw RT, Sangwa N, Forrest LR, Rudnick G) Proc Natl Acad Sci U S A 2021 Mar 09;118(10)       19 Citations
1Evolutionary Conservation of Structural and Functional Coupling between the BRM AT-Hook and Bromodomain. (Lupo BE, Chu P, Harms MJ, Morrison EA, Musselman CA) J Mol Biol 2021 Jul 09;433(14):166845       5 Citations
1Structural insights into histone chaperone Asf1 and its characterization from Plasmodium falciparum. (Srivastava DK, Gunjan S, Das C, Seshadri V, Roy S) Biochem J 2021 Mar 12;478(5):1117-1136       1 Citation
1An Eight Amino Acid Segment Controls Oligomerization and Preferred Conformation of the two Non-visual Arrestins. (Chen Q, Zhuo Y, Sharma P, Perez I, Francis DJ, Chakravarthy S, Vishnivetskiy SA, Berndt S, Hanson SM, Zhan X, Brooks EK, Altenbach C, Hubbell WL, Klug CS, Iverson TM, Gurevich VV) J Mol Biol 2021 Feb 19;433(4):166790       17 Citations
1Characterization of the ExoU activation mechanism using EPR and integrative modeling. (Tessmer MH, DeCero SA, Del Alamo D, Riegert MO, Meiler J, Frank DW, Feix JB) Sci Rep 2020 Nov 12;10(1):19700       11 Citations
1Polymorphisms in STING Affect Human Innate Immune Responses to Poxviruses. (Kennedy RB, Haralambieva IH, Ovsyannikova IG, Voigt EA, Larrabee BR, Schaid DJ, Zimmermann MT, Oberg AL, Poland GA) Front Immunol 2020;11:567348       15 Citations
1An Overview of the Crystallized Structures of the SARS-CoV-2. (Ionescu MI) Protein J 2020 Dec;39(6):600-618       38 Citations
1Puromycin, a selective inhibitor of PSA acts as a substrate for other M1 family aminopeptidases: Biochemical and structural basis. (Reddi R, Ganji RJ, Marapaka AK, Bala SC, Yerra NV, Haque N, Addlagatta A) Int J Biol Macromol 2020 Dec 15;165(Pt A):1373-1381       3 Citations
1Discovery of Drug-Like Ligands for the Mac1 Domain of SARS-CoV-2 Nsp3. (Virdi RS, Bavisotto RV, Hopper NC, Vuksanovic N, Melkonian TR, Silvaggi NR, Frick DN) SLAS Discov 2020 Dec;25(10):1162-1170       24 Citations
2Serial Crystallography for Structure-Based Drug Discovery. (Zhu L, Chen X, Abola EE, Jing L, Liu W) Trends Pharmacol Sci 2020 Nov;41(11):830-839       12 Citations
1Genetic Studies of Leptin Concentrations Implicate Leptin in the Regulation of Early Adiposity. (Yaghootkar H, Zhang Y, Spracklen CN, Karaderi T, Huang LO, Bradfield J, Schurmann C, Fine RS, Preuss MH, Kutalik Z, Wittemans LBL, Lu Y, Metz S, Willems SM, Li-Gao R, Grarup N, Wang S, Molnos S, Sandoval-Zárate AA, Nalls MA, Lange LA, Haesser J, Guo X, Lyytikäinen LP, Feitosa MF, Sitlani CM, Venturini C, Mahajan A, Kacprowski T, Wang CA, Chasman DI, Amin N, Broer L, Robertson N, Young KL, Allison M, Auer PL, Blüher M, Borja JB, Bork-Jensen J, Carrasquilla GD, Christofidou P, Demirkan A, Doege CA, Garcia ME, Graff M, Guo K, Hakonarson H, Hong J, Ida Chen YD, Jackson R, Jakupović H, Jousilahti P, Justice AE, Kähönen M, Kizer JR, Kriebel J, LeDuc CA, Li J, Lind L, Luan J, Mackey DA, Mangino M, Männistö S, Martin Carli JF, Medina-Gomez C, Mook-Kanamori DO, Morris AP, de Mutsert R, Nauck M, Prokic I, Pennell CE, Pradhan AD, Psaty BM, Raitakari OT, Scott RA, Skaaby T, Strauch K, Taylor KD, Teumer A, Uitterlinden AG, Wu Y, Yao J, Walker M, North KE, Kovacs P, Ikram MA, van Duijn CM, Ridker PM, Lye S, Homuth G, Ingelsson E, Spector TD, McKnight B, Province MA, Lehtimäki T, Adair LS, Rotter JI, Reiner AP, Wilson JG, Harris TB, Ripatti S, Grallert H, Meigs JB, Salomaa V, Hansen T, Willems van Dijk K, Wareham NJ, Grant SFA, Langenberg C, Frayling TM, Lindgren CM, Mohlke KL, Leibel RL, Loos RJF, Kilpeläinen TO) Diabetes 2020 Dec;69(12):2806-2818       26 Citations
1Allosteric regulation of lysosomal enzyme recognition by the cation-independent mannose 6-phosphate receptor. (Olson LJ, Misra SK, Ishihara M, Battaile KP, Grant OC, Sood A, Woods RJ, Kim JP, Tiemeyer M, Ren G, Sharp JS, Dahms NM) Commun Biol 2020 Sep 09;3(1):498       21 Citations
1Conformational States of the Cytoprotective Protein Bcl-xL. (Ryzhov P, Tian Y, Yao Y, Bobkov AA, Im W, Marassi FM) Biophys J 2020 Oct 06;119(7):1324-1334       9 Citations
1The Fe-type nitrile hydratase from Rhodococcus equi TG328-2 forms an alpha-activator protein complex. (Lankathilaka KPW, Bennett B, Holz RC) J Biol Inorg Chem 2020 Sep;25(6):903-911       7 Citations
1Mutually constructive roles of Ail and LPS in Yersinia pestis serum survival. (Singh C, Lee H, Tian Y, Schesser Bartra S, Hower S, Fujimoto LM, Yao Y, Ivanov SA, Shaikhutdinova RZ, Anisimov AP, Plano GV, Im W, Marassi FM) Mol Microbiol 2020 Sep;114(3):510-520       16 Citations
1Structural basis for the hydrolytic dehalogenation of the fungicide chlorothalonil. (Catlin DS, Yang X, Bennett B, Holz RC, Liu D) J Biol Chem 2020 Jun 26;295(26):8668-8677       4 Citations
1XFEL and NMR Structures of Francisella Lipoprotein Reveal Conformational Space of Drug Target against Tularemia. (Zook J, Shekhar M, Hansen D, Conrad C, Grant T, Gupta C, White T, Barty A, Basu S, Zhao Y, Zatsepin N, Ishchenko A, Batyuk A, Gati C, Li C, Galli L, Coe J, Hunter M, Liang M, Weierstall U, Nelson G, James D, Stauch B, Craciunescu F, Thifault D, Liu W, Cherezov V, Singharoy A, Fromme P) Structure 2020 May 05;28(5):540-547.e3       7 Citations
1Interpretation of HDX Data by Maximum-Entropy Reweighting of Simulated Structural Ensembles. (Bradshaw RT, Marinelli F, Faraldo-Gómez JD, Forrest LR) Biophys J 2020 Apr 07;118(7):1649-1664       23 Citations
2Structural and mechanistic insights into Hsp104 function revealed by synchrotron X-ray footprinting. (Sweeny EA, Tariq A, Gurpinar E, Go MS, Sochor MA, Kan ZY, Mayne L, Englander SW, Shorter J) J Biol Chem 2020 Feb 07;295(6):1517-1538       13 Citations
2Structure of human Vitronectin C-terminal domain and interaction with Yersinia pestis outer membrane protein Ail. (Shin K, Lechtenberg BC, Fujimoto LM, Yao Y, Bartra SS, Plano GV, Marassi FM) Sci Adv 2019 Sep;5(9):eaax5068       19 Citations
1Structure-function guided modeling of chemokine-GPCR specificity for the chemokine XCL1 and its receptor XCR1. (Fox JC, Thomas MA, Dishman AF, Larsen O, Nakayama T, Yoshie O, Rosenkilde MM, Volkman BF) Sci Signal 2019 Sep 03;12(597)       16 Citations
2Trapping of a Putative Intermediate in the Cytochrome c Nitrite Reductase (ccNiR)-Catalyzed Reduction of Nitrite: Implications for the ccNiR Reaction Mechanism. (Ali M, Stein N, Mao Y, Shahid S, Schmidt M, Bennett B, Pacheco AA) J Am Chem Soc 2019 Aug 28;141(34):13358-13371       22 Citations
1Molecular mechanisms of human P2X3 receptor channel activation and modulation by divalent cation bound ATP. (Li M, Wang Y, Banerjee R, Marinelli F, Silberberg S, Faraldo-Gómez JD, Hattori M, Swartz KJ) Elife 2019 Jun 24;8       7 Citations
3Modeling post-translational modifications and cancer-associated mutations that impact the heterochromatin protein 1α-importin α heterodimers. (Zimmermann MT, Williams MM, Klee EW, Lomberk GA, Urrutia R) Proteins 2019 Nov;87(11):904-916       4 Citations
1Hsp104 and Potentiated Variants Can Operate as Distinct Nonprocessive Translocases. (Durie CL, Lin J, Scull NW, Mack KL, Jackrel ME, Sweeny EA, Castellano LM, Shorter J, Lucius AL) Biophys J 2019 May 21;116(10):1856-1872       14 Citations
1Synthesis of Simplified Azasordarin Analogs as Potential Antifungal Agents. (Wu Y, Dockendorff C) J Org Chem 2019 May 03;84(9):5292-5304       8 Citations
1Molecular modeling of LDLR aids interpretation of genomic variants. (Klee EW, Zimmermann MT) J Mol Med (Berl) 2019 Apr;97(4):533-540       9 Citations
1Angiotensin Analogs with Divergent Bias Stabilize Distinct Receptor Conformations. (Wingler LM, Elgeti M, Hilger D, Latorraca NR, Lerch MT, Staus DP, Dror RO, Kobilka BK, Hubbell WL, Lefkowitz RJ) Cell 2019 Jan 24;176(3):468-478.e11       187 Citations
1Crystal structure of misoprostol bound to the labor inducer prostaglandin E2 receptor. (Audet M, White KL, Breton B, Zarzycka B, Han GW, Lu Y, Gati C, Batyuk A, Popov P, Velasquez J, Manahan D, Hu H, Weierstall U, Liu W, Shui W, Katritch V, Cherezov V, Hanson MA, Stevens RC) Nat Chem Biol 2019 Jan;15(1):11-17       37 Citations
1Humanized GPIbα-von Willebrand factor interaction in the mouse. (Kanaji S, Orje JN, Kanaji T, Kamikubo Y, Morodomi Y, Chen Y, Zarpellon A, Eberhardt J, Forli S, Fahs SA, Sood R, Haberichter SL, Montgomery RR, Ruggeri ZM) Blood Adv 2018 Oct 09;2(19):2522-2532       12 Citations
1The C terminus of the bacterial multidrug transporter EmrE couples drug binding to proton release. (Thomas NE, Wu C, Morrison EA, Robinson AE, Werner JP, Henzler-Wildman KA) J Biol Chem 2018 Dec 07;293(49):19137-19147       16 Citations
1Bare surface of gold nanoparticle induces inflammation through unfolding of plasma fibrinogen. (Kharazian B, Lohse SE, Ghasemi F, Raoufi M, Saei AA, Hashemi F, Farvadi F, Alimohamadi R, Jalali SA, Shokrgozar MA, Hadipour NL, Ejtehadi MR, Mahmoudi M) Sci Rep 2018 Aug 22;8(1):12557       39 Citations
1Structural determinants of 5-HT2B receptor activation and biased agonism. (McCorvy JD, Wacker D, Wang S, Agegnehu B, Liu J, Lansu K, Tribo AR, Olsen RHJ, Che T, Jin J, Roth BL) Nat Struct Mol Biol 2018 Sep;25(9):787-796       107 Citations
1Energy Transduction in Nitrogenase. (Seefeldt LC, Hoffman BM, Peters JW, Raugei S, Beratan DN, Antony E, Dean DR) Acc Chem Res 2018 Sep 18;51(9):2179-2186       98 Citations
1The mitochondrial single-stranded DNA binding protein from S. cerevisiae, Rim1, does not form stable homo-tetramers and binds DNA as a dimer of dimers. (Singh SP, Kukshal V, De Bona P, Antony E, Galletto R) Nucleic Acids Res 2018 Aug 21;46(14):7193-7205       8 Citations
3The Solution Structure of CCL28 Reveals Structural Lability that Does Not Constrain Antifungal Activity. (Thomas MA, He J, Peterson FC, Huppler AR, Volkman BF) J Mol Biol 2018 Sep 14;430(18 Pt B):3266-3282       13 Citations
2A-C Estrogens as Potent and Selective Estrogen Receptor-Beta Agonists (SERBAs) to Enhance Memory Consolidation under Low-Estrogen Conditions. (Hanson AM, Perera KLIS, Kim J, Pandey RK, Sweeney N, Lu X, Imhoff A, Mackinnon AC, Wargolet AJ, Van Hart RM, Frick KM, Donaldson WA, Sem DS) J Med Chem 2018 Jun 14;61(11):4720-4738       18 Citations
1Flavones-bound in benzodiazepine site on GABAA receptor: Concomitant anxiolytic-like and cognitive-enhancing effects produced by Isovitexin and 6-C-glycoside-Diosmetin. (Oliveira DR, Todo AH, Rêgo GM, Cerutti JM, Cavalheiro AJ, Rando DGG, Cerutti SM) Eur J Pharmacol 2018 Jul 15;831:77-86       25 Citations
1The conformation of the histone H3 tail inhibits association of the BPTF PHD finger with the nucleosome. (Morrison EA, Bowerman S, Sylvers KL, Wereszczynski J, Musselman CA) Elife 2018 Apr 12;7       95 Citations
1The membrane-distal regions of integrin α cytoplasmic domains contribute differently to integrin inside-out activation. (Thinn AMM, Wang Z, Zhu J) Sci Rep 2018 Mar 22;8(1):5067       9 Citations
1Calmodulin-induced Conformational Control and Allostery Underlying Neuronal Nitric Oxide Synthase Activation. (Hanson QM, Carley JR, Gilbreath TJ, Smith BC, Underbakke ES) J Mol Biol 2018 Mar 30;430(7):935-947       18 Citations
1Leishmania donovani Inhibitor of Serine Peptidases 2 Mediated Inhibition of Lectin Pathway and Upregulation of C5aR Signaling Promote Parasite Survival inside Host. (Verma S, Mandal A, Ansari MY, Kumar A, Abhishek K, Ghosh AK, Kumar A, Kumar V, Das S, Das P) Front Immunol 2018;9:63       20 Citations
1Unique pharmacological properties of serotoninergic G-protein coupled receptors from cestodes. (Camicia F, Celentano AM, Johns ME, Chan JD, Maldonado L, Vaca H, Di Siervi N, Kamentezky L, Gamo AM, Ortega-Gutierrez S, Martin-Fontecha M, Davio C, Marchant JS, Rosenzvit MC) PLoS Negl Trop Dis 2018 Feb;12(2):e0006267       24 Citations
1Mixed Fluorotryptophan Substitutions at the Same Residue Expand the Versatility of 19 F Protein NMR Spectroscopy. (Kenward C, Shin K, Rainey JK) Chemistry 2018 Mar 07;24(14):3391-3396       15 Citations
1Human P450 CYP17A1: Control of Substrate Preference by Asparagine 202. (Gregory MC, Mak PJ, Khatri Y, Kincaid JR, Sligar SG) Biochemistry 2018 Feb 06;57(5):764-771       9 Citations
1Protonation state of glutamate 73 regulates the formation of a specific dimeric association of mVDAC1. (Bergdoll LA, Lerch MT, Patrick JW, Belardo K, Altenbach C, Bisignano P, Laganowsky A, Grabe M, Hubbell WL, Abramson J) Proc Natl Acad Sci U S A 2018 Jan 09;115(2):E172-E179       32 Citations
1Structure-inspired design of β-arrestin-biased ligands for aminergic GPCRs. (McCorvy JD, Butler KV, Kelly B, Rechsteiner K, Karpiak J, Betz RM, Kormos BL, Shoichet BK, Dror RO, Jin J, Roth BL) Nat Chem Biol 2018 Feb;14(2):126-134       131 Citations
1Maintaining pH-dependent conformational flexibility of M1 is critical for efficient influenza A virus replication. (Chiang MJ, Musayev FN, Kosikova M, Lin Z, Gao Y, Mosier PD, Althufairi B, Ye Z, Zhou Q, Desai UR, Xie H, Safo MK) Emerg Microbes Infect 2017 Dec 06;6(12):e108       10 Citations
1Swit_4259, an acetoacetate decarboxylase-like enzyme from Sphingomonas wittichii RW1. (Mydy LS, Mashhadi Z, Knight TW, Fenske T, Hagemann T, Hoppe RW, Han L, Miller TR, Schwabacher AW, Silvaggi NR) Acta Crystallogr F Struct Biol Commun 2017 Dec 01;73(Pt 12):672-681       2 Citations
1Structural basis of arrestin-3 activation and signaling. (Chen Q, Perry NA, Vishnivetskiy SA, Berndt S, Gilbert NC, Zhuo Y, Singh PK, Tholen J, Ohi MD, Gurevich EV, Brautigam CA, Klug CS, Gurevich VV, Iverson TM) Nat Commun 2017 Nov 10;8(1):1427       90 Citations
1Refrigeration-Induced Binding of von Willebrand Factor Facilitates Fast Clearance of Refrigerated Platelets. (Chen W, Druzak SA, Wang Y, Josephson CD, Hoffmeister KM, Ware J, Li R) Arterioscler Thromb Vasc Biol 2017 Dec;37(12):2271-2279       44 Citations
1A pivotal role for a conserved bulky residue at the α1-helix of the αI integrin domain in ligand binding. (Wang Z, Thinn AMM, Zhu J) J Biol Chem 2017 Dec 15;292(50):20756-20768       9 Citations
1D4 dopamine receptor high-resolution structures enable the discovery of selective agonists. (Wang S, Wacker D, Levit A, Che T, Betz RM, McCorvy JD, Venkatakrishnan AJ, Huang XP, Dror RO, Shoichet BK, Roth BL) Science 2017 Oct 20;358(6361):381-386       172 Citations
1Protein Structure Facilitates High-Resolution Immunological Mapping. (Zuverink M, Barbieri JT) Clin Vaccine Immunol 2017 Dec;24(12)       1 Citation
1Nutrient-driven O-GlcNAc in proteostasis and neurodegeneration. (Akan I, Olivier-Van Stichelen S, Bond MR, Hanover JA) J Neurochem 2018 Jan;144(1):7-34       62 Citations
1A Budding-Defective M2 Mutant Exhibits Reduced Membrane Interaction, Insensitivity to Cholesterol, and Perturbed Interdomain Coupling. (Herneisen AL, Sahu ID, McCarrick RM, Feix JB, Lorigan GA, Howard KP) Biochemistry 2017 Nov 07;56(44):5955-5963       16 Citations
1MrpL35, a mitospecific component of mitoribosomes, plays a key role in cytochrome c oxidase assembly. (Box JM, Kaur J, Stuart RA) Mol Biol Cell 2017 Nov 15;28(24):3489-3499       26 Citations
1Analysing the microenvironment of 2-p-toluidinylnaphthalene-6-sulfonate (TNS) in solvents and in different conformational states of proteins in relation to its fluorescence properties: a computational study. (Haque N, Baratam K, Prabhu NP) Phys Chem Chem Phys 2017 Sep 20;19(36):24656-24666       2 Citations
2Directed evolution provides insight into conformational substrate sampling by SrtA. (Suliman M, Santosh V, Seegar TCM, Dalton AC, Schultz KM, Klug CS, Barton WA) PLoS One 2017;12(8):e0184271       8 Citations
1BRAF mutation as a novel driver of eosinophilic cystitis. (Choi MY, Tsigelny IF, Boichard A, Skjevik ÅA, Shabaik A, Kurzrock R) Cancer Biol Ther 2017 Sep 02;18(9):655-659       5 Citations
1Structural insights into the extracellular recognition of the human serotonin 2B receptor by an antibody. (Ishchenko A, Wacker D, Kapoor M, Zhang A, Han GW, Basu S, Patel N, Messerschmidt M, Weierstall U, Liu W, Katritch V, Roth BL, Stevens RC, Cherezov V) Proc Natl Acad Sci U S A 2017 Aug 01;114(31):8223-8228       56 Citations
1The importance of N-glycosylation on β3 integrin ligand binding and conformational regulation. (Cai X, Thinn AMM, Wang Z, Shan H, Zhu J) Sci Rep 2017 Jul 05;7(1):4656       52 Citations
4Structure and Dimerization of IreB, a Negative Regulator of Cephalosporin Resistance in Enterococcus faecalis. (Hall CL, Lytle BL, Jensen D, Hoff JS, Peterson FC, Volkman BF, Kristich CJ) J Mol Biol 2017 Jul 21;429(15):2324-2336       16 Citations
1Bioactivity of the putative apelin proprotein expands the repertoire of apelin receptor ligands. (Shin K, Chapman NA, Sarker M, Kenward C, Huang SK, Weatherbee-Martin N, Pandey A, Dupré DJ, Rainey JK) Biochim Biophys Acta Gen Subj 2017 Aug;1861(8):1901-1912       29 Citations
1Multiple States of Nitrile Hydratase from Rhodococcus equi TG328-2: Structural and Mechanistic Insights from Electron Paramagnetic Resonance and Density Functional Theory Studies. (Stein N, Gumataotao N, Hajnas N, Wu R, Lankathilaka KPW, Bornscheuer UT, Liu D, Fiedler AT, Holz RC, Bennett B) Biochemistry 2017 Jun 20;56(24):3068-3077       9 Citations
1Functional and structural consequences of chemokine (C-X-C motif) receptor 4 activation with cognate and non-cognate agonists. (Eby JM, Abdelkarim H, Albee LJ, Tripathi A, Gao X, Volkman BF, Gaponenko V, Majetschak M) Mol Cell Biochem 2017 Oct;434(1-2):143-151       15 Citations
1Structural basis for selectivity and diversity in angiotensin II receptors. (Zhang H, Han GW, Batyuk A, Ishchenko A, White KL, Patel N, Sadybekov A, Zamlynny B, Rudd MT, Hollenstein K, Tolstikova A, White TA, Hunter MS, Weierstall U, Liu W, Babaoglu K, Moore EL, Katz RD, Shipman JM, Garcia-Calvo M, Sharma S, Sheth P, Soisson SM, Stevens RC, Katritch V, Cherezov V) Nature 2017 Apr 20;544(7650):327-332       177 Citations
1The growing world of small heat shock proteins: from structure to functions. (Carra S, Alberti S, Arrigo PA, Benesch JL, Benjamin IJ, Boelens W, Bartelt-Kirbach B, Brundel BJJM, Buchner J, Bukau B, Carver JA, Ecroyd H, Emanuelsson C, Finet S, Golenhofen N, Goloubinoff P, Gusev N, Haslbeck M, Hightower LE, Kampinga HH, Klevit RE, Liberek K, Mchaourab HS, McMenimen KA, Poletti A, Quinlan R, Strelkov SV, Toth ME, Vierling E, Tanguay RM) Cell Stress Chaperones 2017 Jul;22(4):601-611       135 Citations
1Glucose-6-phosphate dehydrogenase and Trypanothione reductase interaction protects Leishmania donovani from metalloid mediated oxidative stress. (Ghosh AK, Saini S, Das S, Mandal A, Sardar AH, Ansari MY, Abhishek K, Kumar A, Singh R, Verma S, Equbal A, Ali V, Das P) Free Radic Biol Med 2017 May;106:10-23       20 Citations
1Apela exhibits isoform- and headgroup-dependent modulation of micelle binding, peptide conformation and dynamics. (Huang SK, Shin K, Sarker M, Rainey JK) Biochim Biophys Acta Biomembr 2017 May;1859(5):767-778       26 Citations
2Cooperative Substrate-Cofactor Interactions and Membrane Localization of the Bacterial Phospholipase A2 (PLA2) Enzyme, ExoU. (Tessmer MH, Anderson DM, Buchaklian A, Frank DW, Feix JB) J Biol Chem 2017 Feb 24;292(8):3411-3419       26 Citations
1Predicted Structures of the Proton-Bound Membrane-Embedded Rotor Rings of the Saccharomyces cerevisiae and Escherichia coli ATP Synthases. (Zhou W, Leone V, Krah A, Faraldo-Gómez JD) J Phys Chem B 2017 Apr 20;121(15):3297-3307       6 Citations
1Differences in the Phosphorylation-Dependent Regulation of Prenylation of Rap1A and Rap1B. (Wilson JM, Prokop JW, Lorimer E, Ntantie E, Williams CL) J Mol Biol 2016 Dec 04;428(24 Pt B):4929-4945       22 Citations
1Crystal structure analysis in Zn2+-bound state and biophysical characterization of CLas-ZnuA2. (Sharma N, Selvakumar P, Saini G, Warghane A, Ghosh DK, Sharma AK) Biochim Biophys Acta 2016 Dec;1864(12):1649-1657       13 Citations
2Successful Strategies to Determine High-Resolution Structures of GPCRs. (Xiang J, Chun E, Liu C, Jing L, Al-Sahouri Z, Zhu L, Liu W) Trends Pharmacol Sci 2016 Dec;37(12):1055-1069       56 Citations
1Crystallographic Structure of Truncated CCL21 and the Putative Sulfotyrosine-Binding Site. (Smith EW, Lewandowski EM, Moussouras NA, Kroeck KG, Volkman BF, Veldkamp CT, Chen Y) Biochemistry 2016 Oct 11;55(40):5746-5753       11 Citations
1Evolution of a Protein Interaction Domain Family by Tuning Conformational Flexibility. (Whitney DS, Volkman BF, Prehoda KE) J Am Chem Soc 2016 Nov 23;138(46):15150-15156       14 Citations
2Tyrosine-sulfated V2 peptides inhibit HIV-1 infection via coreceptor mimicry. (Cimbro R, Peterson FC, Liu Q, Guzzo C, Zhang P, Miao H, Van Ryk D, Ambroggio X, Hurt DE, De Gioia L, Volkman BF, Dolan MA, Lusso P) EBioMedicine 2016 Aug;10:45-54       16 Citations
1Kinetics of protein fibril formation: Methods and mechanisms. (Kumar EK, Haque N, Prabhu NP) Int J Biol Macromol 2017 Jul;100:3-10       45 Citations
1Evidence That the Pi Release Event Is the Rate-Limiting Step in the Nitrogenase Catalytic Cycle. (Yang ZY, Ledbetter R, Shaw S, Pence N, Tokmina-Lukaszewska M, Eilers B, Guo Q, Pokhrel N, Cash VL, Dean DR, Antony E, Bothner B, Peters JW, Seefeldt LC) Biochemistry 2016 Jul 05;55(26):3625-35       93 Citations
1Mechanism of extracellular ion exchange and binding-site occlusion in a sodium/calcium exchanger. (Liao J, Marinelli F, Lee C, Huang Y, Faraldo-Gómez JD, Jiang Y) Nat Struct Mol Biol 2016 Jun;23(6):590-599       74 Citations
1Lid dynamics of porcine pancreatic lipase in non-aqueous solvents. (Haque N, Prabhu NP) Biochim Biophys Acta 2016 Oct;1860(10):2326-34       20 Citations
1Lid closure dynamics of porcine pancreatic lipase in aqueous solution. (Haque N, Prabhu NP) Biochim Biophys Acta 2016 Oct;1860(10):2313-25       11 Citations
1An IRF5 Decoy Peptide Reduces Myocardial Inflammation and Fibrosis and Improves Endothelial Cell Function in Tight-Skin Mice. (Weihrauch D, Krolikowski JG, Jones DW, Zaman T, Bamkole O, Struve J, Pillai S, Pagel PS, Lohr NL, Pritchard KA Jr) PLoS One 2016;11(4):e0151999       10 Citations
1The Role of ANK in Calcium Pyrophosphate Deposition Disease. (Mitton-Fitzgerald E, Gohr CM, Bettendorf B, Rosenthal AK) Curr Rheumatol Rep 2016 May;18(5):25       24 Citations
1Characterization of the membrane-inserted C-terminus of cytoprotective BCL-XL. (Yao Y, Nisan D, Fujimoto LM, Antignani A, Barnes A, Tjandra N, Youle RJ, Marassi FM) Protein Expr Purif 2016 Jun;122:56-63       20 Citations
1Role of Chromatin Structural Changes in Regulating Human CYP3A Ontogeny. (Giebel NL, Shadley JD, McCarver DG, Dorko K, Gramignoli R, Strom SC, Yan K, Simpson PM, Hines RN) Drug Metab Dispos 2016 Jul;44(7):1027-37       5 Citations
1Ribosome Mechanics Informs about Mechanism. (Zimmermann MT, Jia K, Jernigan RL) J Mol Biol 2016 Feb 27;428(5 Pt A):802-810       19 Citations
1Ternary structure reveals mechanism of a membrane diacylglycerol kinase. (Li D, Stansfeld PJ, Sansom MSP, Keogh A, Vogeley L, Howe N, Lyons JA, Aragao D, Fromme P, Fromme R, Basu S, Grotjohann I, Kupitz C, Rendek K, Weierstall U, Zatsepin NA, Cherezov V, Liu W, Bandaru S, English NJ, Gati C, Barty A, Yefanov O, Chapman HN, Diederichs K, Messerschmidt M, Boutet S, Williams GJ, Marvin Seibert M, Caffrey M) Nat Commun 2015 Dec 17;6:10140       31 Citations
1Unveiling the crucial intermediates in androgen production. (Mak PJ, Gregory MC, Denisov IG, Sligar SG, Kincaid JR) Proc Natl Acad Sci U S A 2015 Dec 29;112(52):15856-61       67 Citations
1Mechanistic and Structural Insights into the Prion-Disaggregase Activity of Hsp104. (Sweeny EA, Shorter J) J Mol Biol 2016 May 08;428(9 Pt B):1870-85       68 Citations
1The dependence of chemokine-glycosaminoglycan interactions on chemokine oligomerization. (Dyer DP, Salanga CL, Volkman BF, Kawamura T, Handel TM) Glycobiology 2016 Mar;26(3):312-26       85 Citations
1Streptomyces wadayamensis MppP Is a Pyridoxal 5'-Phosphate-Dependent L-Arginine α-Deaminase, γ-Hydroxylase in the Enduracididine Biosynthetic Pathway. (Han L, Schwabacher AW, Moran GR, Silvaggi NR) Biochemistry 2015 Dec 01;54(47):7029-40       34 Citations
1High-Pressure EPR and Site-Directed Spin Labeling for Mapping Molecular Flexibility in Proteins. (Lerch MT, Yang Z, Altenbach C, Hubbell WL) Methods Enzymol 2015;564:29-57       14 Citations
1Saturation Recovery EPR and Nitroxide Spin Labeling for Exploring Structure and Dynamics in Proteins. (Yang Z, Bridges M, Lerch MT, Altenbach C, Hubbell WL) Methods Enzymol 2015;564:3-27       19 Citations
1Linker regions and flexibility around the metalloprotease domain account for conformational activation of ADAMTS-13. (Deforche L, Roose E, Vandenbulcke A, Vandeputte N, Feys HB, Springer TA, Mi LZ, Muia J, Sadler JE, Soejima K, Rottensteiner H, Deckmyn H, De Meyer SF, Vanhoorelbeke K) J Thromb Haemost 2015 Nov;13(11):2063-75       59 Citations
1Full engagement of liganded maltose-binding protein stabilizes a semi-open ATP-binding cassette dimer in the maltose transporter. (Alvarez FJ, Orelle C, Huang Y, Bajaj R, Everly RM, Klug CS, Davidson AL) Mol Microbiol 2015 Dec;98(5):878-94       29 Citations
1Solution Structure of CCL19 and Identification of Overlapping CCR7 and PSGL-1 Binding Sites. (Veldkamp CT, Kiermaier E, Gabel-Eissens SJ, Gillitzer ML, Lippner DR, DiSilvio FA, Mueller CJ, Wantuch PL, Chaffee GR, Famiglietti MW, Zgoba DM, Bailey AA, Bah Y, Engebretson SJ, Graupner DR, Lackner ER, LaRosa VD, Medeiros T, Olson ML, Phillips AJ, Pyles H, Richard AM, Schoeller SJ, Touzeau B, Williams LG, Sixt M, Peterson FC) Biochemistry 2015 Jul 14;54(27):4163-6       36 Citations
1Ensemble-Biased Metadynamics: A Molecular Simulation Method to Sample Experimental Distributions. (Marinelli F, Faraldo-Gómez JD) Biophys J 2015 Jun 16;108(12):2779-82       58 Citations
2Correlations between the Electronic Properties of Shewanella oneidensis Cytochrome c Nitrite Reductase (ccNiR) and Its Structure: Effects of Heme Oxidation State and Active Site Ligation. (Stein N, Love D, Judd ET, Elliott SJ, Bennett B, Pacheco AA) Biochemistry 2015 Jun 23;54(24):3749-58       10 Citations
1Bacterial Renalase: Structure and Kinetics of an Enzyme with 2- and 6-Dihydro-β-NAD(P) Oxidase Activity from Pseudomonas phaseolicola. (Hoag MR, Roman J, Beaupre BA, Silvaggi NR, Moran GR) Biochemistry 2015 Jun 23;54(24):3791-802       18 Citations
1Probing the role of Proline in the antimicrobial activity and lipopolysaccharide binding of indolicidin. (Bera S, Ghosh A, Sharma S, Debnath T, Giri B, Bhunia A) J Colloid Interface Sci 2015 Aug 15;452:148-159       21 Citations
1Electron capture dissociation and drift tube ion mobility-mass spectrometry coupled with site directed mutations provide insights into the conformational diversity of a metamorphic protein. (Harvey SR, Porrini M, Tyler RC, MacPhee CE, Volkman BF, Barran PE) Phys Chem Chem Phys 2015 Apr 28;17(16):10538-50       16 Citations
1Conformation of BCL-XL upon Membrane Integration. (Yao Y, Fujimoto LM, Hirshman N, Bobkov AA, Antignani A, Youle RJ, Marassi FM) J Mol Biol 2015 Jul 03;427(13):2262-70       50 Citations
1On the principle of ion selectivity in Na+/H+-coupled membrane proteins: experimental and theoretical studies of an ATP synthase rotor. (Leone V, Pogoryelov D, Meier T, Faraldo-Gómez JD) Proc Natl Acad Sci U S A 2015 Mar 10;112(10):E1057-66       32 Citations
2Crucial role for the VWF A1 domain in binding to type IV collagen. (Flood VH, Schlauderaff AC, Haberichter SL, Slobodianuk TL, Jacobi PM, Bellissimo DB, Christopherson PA, Friedman KD, Gill JC, Hoffmann RG, Montgomery RR, Zimmerman Program Investigators) Blood 2015 Apr 02;125(14):2297-304       79 Citations
1Structure and function of serotonin G protein-coupled receptors. (McCorvy JD, Roth BL) Pharmacol Ther 2015 Jun;150:129-42       266 Citations
2Structure-function analysis of CCL28 in the development of post-viral asthma. (Thomas MA, Buelow BJ, Nevins AM, Jones SE, Peterson FC, Gundry RL, Grayson MH, Volkman BF) J Biol Chem 2015 Feb 13;290(7):4528-36       19 Citations
1You are lost without a map: Navigating the sea of protein structures. (Lamb AL, Kappock TJ, Silvaggi NR) Biochim Biophys Acta 2015 Apr;1854(4):258-68       23 Citations
1Steric parameters, molecular modeling and hydropathic interaction analysis of the pharmacology of para-substituted methcathinone analogues. (Sakloth F, Kolanos R, Mosier PD, Bonano JS, Banks ML, Partilla JS, Baumann MH, Negus SS, Glennon RA) Br J Pharmacol 2015 May;172(9):2210-8       37 Citations
1Sodium recognition by the Na+/Ca2+ exchanger in the outward-facing conformation. (Marinelli F, Almagor L, Hiller R, Giladi M, Khananshvili D, Faraldo-Gómez JD) Proc Natl Acad Sci U S A 2014 Dec 16;111(50):E5354-62       61 Citations
1Intrinsic disorder drives N-terminal ubiquitination by Ube2w. (Vittal V, Shi L, Wenzel DM, Scaglione KM, Duncan ED, Basrur V, Elenitoba-Johnson KS, Baker D, Paulson HL, Brzovic PS, Klevit RE) Nat Chem Biol 2015 Jan;11(1):83-9       63 Citations
1Inactivating mutations in NPC1L1 and protection from coronary heart disease. (Myocardial Infarction Genetics Consortium Investigators, Stitziel NO, Won HH, Morrison AC, Peloso GM, Do R, Lange LA, Fontanillas P, Gupta N, Duga S, Goel A, Farrall M, Saleheen D, Ferrario P, König I, Asselta R, Merlini PA, Marziliano N, Notarangelo MF, Schick U, Auer P, Assimes TL, Reilly M, Wilensky R, Rader DJ, Hovingh GK, Meitinger T, Kessler T, Kastrati A, Laugwitz KL, Siscovick D, Rotter JI, Hazen SL, Tracy R, Cresci S, Spertus J, Jackson R, Schwartz SM, Natarajan P, Crosby J, Muzny D, Ballantyne C, Rich SS, O'Donnell CJ, Abecasis G, Sunaev S, Nickerson DA, Buring JE, Ridker PM, Chasman DI, Austin E, Kullo IJ, Weeke PE, Shaffer CM, Bastarache LA, Denny JC, Roden DM, Palmer C, Deloukas P, Lin DY, Tang ZZ, Erdmann J, Schunkert H, Danesh J, Marrugat J, Elosua R, Ardissino D, McPherson R, Watkins H, Reiner AP, Wilson JG, Altshuler D, Gibbs RA, Lander ES, Boerwinkle E, Gabriel S, Kathiresan S) N Engl J Med 2014 Nov 27;371(22):2072-82       373 Citations
1The solution structure of the forkhead box-O DNA binding domain of Brugia malayi DAF-16a. (Casper SK, Schoeller SJ, Zgoba DM, Phillips AJ, Morien TJ, Chaffee GR, Sackett PC, Peterson FC, Crossgrove K, Veldkamp CT) Proteins 2014 Dec;82(12):3490-6       4 Citations
1Sequence co-evolution gives 3D contacts and structures of protein complexes. (Hopf TA, Schärfe CP, Rodrigues JP, Green AG, Kohlbacher O, Sander C, Bonvin AM, Marks DS) Elife 2014 Sep 25;3       365 Citations
1GPCR crystallization using lipidic cubic phase technique. (Yin X, Xu H, Hanson M, Liu W) Curr Pharm Biotechnol 2014;15(10):971-9       8 Citations
1Michael acceptor approach to the design of new salvinorin A-based high affinity ligands for the kappa-opioid receptor. (Polepally PR, Huben K, Vardy E, Setola V, Mosier PD, Roth BL, Zjawiony JK) Eur J Med Chem 2014 Oct 06;85:818-29       25 Citations
1PconsFold: improved contact predictions improve protein models. (Michel M, Hayat S, Skwark MJ, Sander C, Marks DS, Elofsson A) Bioinformatics 2014 Sep 01;30(17):i482-8       85 Citations
1Hydrogen bonding networks tune proton-coupled redox steps during the enzymatic six-electron conversion of nitrite to ammonia. (Judd ET, Stein N, Pacheco AA, Elliott SJ) Biochemistry 2014 Sep 09;53(35):5638-46       23 Citations
1Structure of the membrane protein MerF, a bacterial mercury transporter, improved by the inclusion of chemical shift anisotropy constraints. (Tian Y, Lu GJ, Marassi FM, Opella SJ) J Biomol NMR 2014 Sep;60(1):67-71       17 Citations
1Chemosensory regulation of a HEAT-repeat protein couples aggregation and sporulation in Myxococcus xanthus. (Darnell CL, Wilson JM, Tiwari N, Fuentes EJ, Kirby JR) J Bacteriol 2014 Sep;196(17):3160-8       10 Citations
2Differential coupling of KLF10 to Sin3-HDAC and PCAF regulates the inducibility of the FOXP3 gene. (Xiong Y, Svingen PA, Sarmento OO, Smyrk TC, Dave M, Khanna S, Lomberk GA, Urrutia RA, Faubion WA Jr) Am J Physiol Regul Integr Comp Physiol 2014 Sep 15;307(6):R608-20       24 Citations
1TNNI3K mutation in familial syndrome of conduction system disease, atrial tachyarrhythmia and dilated cardiomyopathy. (Theis JL, Zimmermann MT, Larsen BT, Rybakova IN, Long PA, Evans JM, Middha S, de Andrade M, Moss RL, Wieben ED, Michels VV, Olson TM) Hum Mol Genet 2014 Nov 01;23(21):5793-804       44 Citations
1Femtosecond crystallography of membrane proteins in the lipidic cubic phase. (Liu W, Wacker D, Wang C, Abola E, Cherezov V) Philos Trans R Soc Lond B Biol Sci 2014 Jul 17;369(1647):20130314       44 Citations
1Elastic network models capture the motions apparent within ensembles of RNA structures. (Zimmermann MT, Jernigan RL) RNA 2014 Jun;20(6):792-804       26 Citations
1A practical implicit solvent potential for NMR structure calculation. (Tian Y, Schwieters CD, Opella SJ, Marassi FM) J Magn Reson 2014 Jun;243:54-64       38 Citations
1FreeContact: fast and free software for protein contact prediction from residue co-evolution. (Kaján L, Hopf TA, Kalaš M, Marks DS, Rost B) BMC Bioinformatics 2014 Mar 26;15:85       134 Citations
1Structure of the human P2Y12 receptor in complex with an antithrombotic drug. (Zhang K, Zhang J, Gao ZG, Zhang D, Zhu L, Han GW, Moss SM, Paoletta S, Kiselev E, Lu W, Fenalti G, Zhang W, Müller CE, Yang H, Jiang H, Cherezov V, Katritch V, Jacobson KA, Stevens RC, Wu B, Zhao Q) Nature 2014 May 01;509(7498):115-8       319 Citations
1Factors correlating with significant differences between X-ray structures of myoglobin. (Rashin AA, Domagalski MJ, Zimmermann MT, Minor W, Chruszcz M, Jernigan RL) Acta Crystallogr D Biol Crystallogr 2014 Feb;70(Pt 2):481-91       8 Citations
1The CD8-derived chemokine XCL1/lymphotactin is a conformation-dependent, broad-spectrum inhibitor of HIV-1. (Guzzo C, Fox J, Lin Y, Miao H, Cimbro R, Volkman BF, Fauci AS, Lusso P) PLoS Pathog 2013;9(12):e1003852       33 Citations
1Serial femtosecond crystallography of G protein-coupled receptors. (Liu W, Wacker D, Gati C, Han GW, James D, Wang D, Nelson G, Weierstall U, Katritch V, Barty A, Zatsepin NA, Li D, Messerschmidt M, Boutet S, Williams GJ, Koglin JE, Seibert MM, Wang C, Shah ST, Basu S, Fromme R, Kupitz C, Rendek KN, Grotjohann I, Fromme P, Kirian RA, Beyerlein KR, White TA, Chapman HN, Caffrey M, Spence JC, Stevens RC, Cherezov V) Science 2013 Dec 20;342(6165):1521-4       396 Citations
1Circular dichroism and site-directed spin labeling reveal structural and dynamical features of high-pressure states of myoglobin. (Lerch MT, Horwitz J, McCoy J, Hubbell WL) Proc Natl Acad Sci U S A 2013 Dec 03;110(49):E4714-22       45 Citations
1The role of a sodium ion binding site in the allosteric modulation of the A(2A) adenosine G protein-coupled receptor. (Gutiérrez-de-Terán H, Massink A, Rodríguez D, Liu W, Han GW, Joseph JS, Katritch I, Heitman LH, Xia L, Ijzerman AP, Cherezov V, Katritch V, Stevens RC) Structure 2013 Dec 03;21(12):2175-85       111 Citations
1Functionally diverse biotin-dependent enzymes with oxaloacetate decarboxylase activity. (Lietzan AD, St Maurice M) Arch Biochem Biophys 2014 Feb 15;544:75-86       19 Citations
1The interdomain interface in bifunctional enzyme protein 3/4A (NS3/4A) regulates protease and helicase activities. (Aydin C, Mukherjee S, Hanson AM, Frick DN, Schiffer CA) Protein Sci 2013 Dec;22(12):1786-98       18 Citations
1Chemotype-selective modes of action of κ-opioid receptor agonists. (Vardy E, Mosier PD, Frankowski KJ, Wu H, Katritch V, Westkaemper RB, Aubé J, Stevens RC, Roth BL) J Biol Chem 2013 Nov 29;288(48):34470-83    
1Structure-based ligand discovery targeting orthosteric and allosteric pockets of dopamine receptors. (Lane JR, Chubukov P, Liu W, Canals M, Cherezov V, Abagyan R, Stevens RC, Katritch V) Mol Pharmacol 2013 Dec;84(6):794-807       82 Citations
1Following easy slope paths on a free energy landscape: the case study of the Trp-cage folding mechanism. (Marinelli F) Biophys J 2013 Sep 03;105(5):1236-47       17 Citations
1Nitric oxide synthase domain interfaces regulate electron transfer and calmodulin activation. (Smith BC, Underbakke ES, Kulp DW, Schief WR, Marletta MA) Proc Natl Acad Sci U S A 2013 Sep 17;110(38):E3577-86       85 Citations
1Membrane protein structure determination: back to the membrane. (Yao Y, Ding Y, Tian Y, Opella SJ, Marassi FM) Methods Mol Biol 2013;1063:145-58       9 Citations
1Two-state dynamics of the SH3-SH2 tandem of Abl kinase and the allosteric role of the N-cap. (Corbi-Verge C, Marinelli F, Zafra-Ruano A, Ruiz-Sanz J, Luque I, Faraldo-Gómez JD) Proc Natl Acad Sci U S A 2013 Sep 03;110(36):E3372-80       32 Citations
1The structure of the mercury transporter MerF in phospholipid bilayers: a large conformational rearrangement results from N-terminal truncation. (Lu GJ, Tian Y, Vora N, Marassi FM, Opella SJ) J Am Chem Soc 2013 Jun 26;135(25):9299-302       29 Citations
1Structural and functional characterization of MppR, an enduracididine biosynthetic enzyme from streptomyces hygroscopicus: functional diversity in the acetoacetate decarboxylase-like superfamily. (Burroughs AM, Hoppe RW, Goebel NC, Sayyed BH, Voegtline TJ, Schwabacher AW, Zabriskie TM, Silvaggi NR) Biochemistry 2013 Jul 02;52(26):4492-506       25 Citations
1Structure-based studies of chemokine receptors. (Zhu L, Zhao Q, Wu B) Curr Opin Struct Biol 2013 Aug;23(4):539-46       21 Citations
2C560Rβ3 caused platelet integrin αII b β3 to bind fibrinogen continuously, but resulted in a severe bleeding syndrome and increased murine mortality. (Fang J, Nurden P, North P, Nurden AT, Du LM, Valentin N, Wilcox DA) J Thromb Haemost 2013 Jun;11(6):1163-71       18 Citations
1The discreet charm of the curve. (Marassi FM) Biophys J 2013 Mar 19;104(6):1215-6       3 Citations
2Structural features for functional selectivity at serotonin receptors. (Wacker D, Wang C, Katritch V, Han GW, Huang XP, Vardy E, McCorvy JD, Jiang Y, Chu M, Siu FY, Liu W, Xu HE, Cherezov V, Roth BL, Stevens RC) Science 2013 May 03;340(6132):615-9       583 Citations
2Structural basis for molecular recognition at serotonin receptors. (Wang C, Jiang Y, Ma J, Wu H, Wacker D, Katritch V, Han GW, Liu W, Huang XP, Vardy E, McCorvy JD, Gao X, Zhou XE, Melcher K, Zhang C, Bai F, Yang H, Yang L, Jiang H, Roth BL, Cherezov V, Stevens RC, Xu HE) Science 2013 May 03;340(6132):610-4       440 Citations
1Extensive rigid analogue design maps the binding conformation of potent N-benzylphenethylamine 5-HT2A serotonin receptor agonist ligands. (Juncosa JI Jr, Hansen M, Bonner LA, Cueva JP, Maglathlin R, McCorvy JD, Marona-Lewicka D, Lill MA, Nichols DE) ACS Chem Neurosci 2013 Jan 16;4(1):96-109       46 Citations
1Genetic heterogeneity of diffuse large B-cell lymphoma. (Zhang J, Grubor V, Love CL, Banerjee A, Richards KL, Mieczkowski PA, Dunphy C, Choi W, Au WY, Srivastava G, Lugar PL, Rizzieri DA, Lagoo AS, Bernal-Mizrachi L, Mann KP, Flowers C, Naresh K, Evens A, Gordon LI, Czader M, Gill JI, Hsi ED, Liu Q, Fan A, Walsh K, Jima D, Smith LL, Johnson AJ, Byrd JC, Luftig MA, Ni T, Zhu J, Chadburn A, Levy S, Dunson D, Dave SS) Proc Natl Acad Sci U S A 2013 Jan 22;110(4):1398-403       460 Citations
1On the specificity of heparin/heparan sulfate binding to proteins. Anion-binding sites on antithrombin and thrombin are fundamentally different. (Mosier PD, Krishnasamy C, Kellogg GE, Desai UR) PLoS One 2012;7(11):e48632       49 Citations
2Electrostatic optimization of the conformational energy landscape in a metamorphic protein. (Tyler RC, Wieting JC, Peterson FC, Volkman BF) Biochemistry 2012 Nov 13;51(45):9067-75       17 Citations
1Crystal structure of a voltage-gated K+ channel pore module in a closed state in lipid membranes. (Santos JS, Asmar-Rovira GA, Han GW, Liu W, Syeda R, Cherezov V, Baker KA, Stevens RC, Montal M) J Biol Chem 2012 Dec 14;287(51):43063-70       23 Citations
1The compensatory G88R change is essential in restoring the normal functions of influenza A/WSN/33 virus matrix protein 1 with a disrupted nuclear localization signal. (Xie H, Lin Z, Mosier PD, Desai UR, Gao Y) J Virol 2013 Jan;87(1):345-53       8 Citations
1Improved chemical shift prediction by Rosetta conformational sampling. (Tian Y, Opella SJ, Marassi FM) J Biomol NMR 2012 Nov;54(3):237-43       6 Citations
1MED25 is a mediator component of HNF4α-driven transcription leading to insulin secretion in pancreatic beta-cells. (Han EH, Rha GB, Chi YI) PLoS One 2012;7(8):e44007       13 Citations
2E2-binding surface on Uba3 β-grasp domain undergoes a conformational transition. (Elgin ES, Sökmen N, Peterson FC, Volkman BF, Dağ C, Haas AL) Proteins 2012 Oct;80(10):2482-7       3 Citations
1Structural basis for allosteric regulation of GPCRs by sodium ions. (Liu W, Chun E, Thompson AA, Chubukov P, Xu F, Katritch V, Han GW, Roth CB, Heitman LH, IJzerman AP, Cherezov V, Stevens RC) Science 2012 Jul 13;337(6091):232-6       789 Citations
1Nascent high density lipoproteins formed by ABCA1 resemble lipid rafts and are structurally organized by three apoA-I monomers. (Sorci-Thomas MG, Owen JS, Fulp B, Bhat S, Zhu X, Parks JS, Shah D, Jerome WG, Gerelus M, Zabalawi M, Thomas MJ) J Lipid Res 2012 Sep;53(9):1890-909       102 Citations
1A computational investigation on the connection between dynamics properties of ribosomal proteins and ribosome assembly. (Burton B, Zimmermann MT, Jernigan RL, Wang Y) PLoS Comput Biol 2012;8(5):e1002530       22 Citations
1Engineering rotor ring stoichiometries in the ATP synthase. (Pogoryelov D, Klyszejko AL, Krasnoselska GO, Heller EM, Leone V, Langer JD, Vonck J, Müller DJ, Faraldo-Gómez JD, Meier T) Proc Natl Acad Sci U S A 2012 Jun 19;109(25):E1599-608       81 Citations
1Structure of the nociceptin/orphanin FQ receptor in complex with a peptide mimetic. (Thompson AA, Liu W, Chun E, Katritch V, Wu H, Vardy E, Huang XP, Trapella C, Guerrini R, Calo G, Roth BL, Cherezov V, Stevens RC) Nature 2012 May 16;485(7398):395-9       418 Citations
2Structure-guided design of A(3) adenosine receptor-selective nucleosides: combination of 2-arylethynyl and bicyclo[3.1.0]hexane substitutions. (Tosh DK, Deflorian F, Phan K, Gao ZG, Wan TC, Gizewski E, Auchampach JA, Jacobson KA) J Med Chem 2012 May 24;55(10):4847-60       77 Citations
1Combining statistical potentials with dynamics-based entropies improves selection from protein decoys and docking poses. (Zimmermann MT, Leelananda SP, Kloczkowski A, Jernigan RL) J Phys Chem B 2012 Jun 14;116(23):6725-31       22 Citations
1Antibodies causing thrombocytopenia in patients treated with RGD-mimetic platelet inhibitors recognize ligand-specific conformers of αIIb/β3 integrin. (Bougie DW, Rasmussen M, Zhu J, Aster RH) Blood 2012 Jun 28;119(26):6317-25       35 Citations
2Structure of the human κ-opioid receptor in complex with JDTic. (Wu H, Wacker D, Mileni M, Katritch V, Han GW, Vardy E, Liu W, Thompson AA, Huang XP, Carroll FI, Mascarella SW, Westkaemper RB, Mosier PD, Roth BL, Cherezov V, Stevens RC) Nature 2012 Mar 21;485(7398):327-32       775 Citations
1Remotely activated protein-producing nanoparticles. (Schroeder A, Goldberg MS, Kastrup C, Wang Y, Jiang S, Joseph BJ, Levins CG, Kannan ST, Langer R, Anderson DG) Nano Lett 2012 Jun 13;12(6):2685-9       93 Citations
1Laue crystal structure of Shewanella oneidensis cytochrome c nitrite reductase from a high-yield expression system. (Youngblut M, Judd ET, Srajer V, Sayyed B, Goelzer T, Elliott SJ, Schmidt M, Pacheco AA) J Biol Inorg Chem 2012 Apr;17(4):647-62       51 Citations
1CD36 ectodomain phosphorylation blocks thrombospondin-1 binding: structure-function relationships and regulation by protein kinase C. (Chu LY, Silverstein RL) Arterioscler Thromb Vasc Biol 2012 Mar;32(3):760-7       33 Citations
1Molecular structure and peptidoglycan recognition of Mycobacterium tuberculosis ArfA (Rv0899). (Yao Y, Barghava N, Kim J, Niederweis M, Marassi FM) J Mol Biol 2012 Feb 17;416(2):208-20       16 Citations
1Antiparallel EmrE exports drugs by exchanging between asymmetric structures. (Morrison EA, DeKoster GT, Dutta S, Vafabakhsh R, Clarkson MW, Bahl A, Kern D, Ha T, Henzler-Wildman KA) Nature 2011 Dec 18;481(7379):45-50       173 Citations
2Potent and selective activation of abscisic acid receptors in vivo by mutational stabilization of their agonist-bound conformation. (Mosquna A, Peterson FC, Park SY, Lozano-Juste J, Volkman BF, Cutler SR) Proc Natl Acad Sci U S A 2011 Dec 20;108(51):20838-43       83 Citations
1Evidence for an allosteric mechanism of substrate release from membrane-transporter accessory binding proteins. (Marinelli F, Kuhlmann SI, Grell E, Kunte HJ, Ziegler C, Faraldo-Gómez JD) Proc Natl Acad Sci U S A 2011 Dec 06;108(49):E1285-92       26 Citations
1AssignFit: a program for simultaneous assignment and structure refinement from solid-state NMR spectra. (Tian Y, Schwieters CD, Opella SJ, Marassi FM) J Magn Reson 2012 Jan;214(1):42-50       17 Citations
1Proteostasis and REDOX state in the heart. (Christians ES, Benjamin IJ) Am J Physiol Heart Circ Physiol 2012 Jan 01;302(1):H24-37       59 Citations
1Conversion of the enzyme guanylate kinase into a mitotic-spindle orienting protein by a single mutation that inhibits GMP-induced closing. (Johnston CA, Whitney DS, Volkman BF, Doe CQ, Prehoda KE) Proc Natl Acad Sci U S A 2011 Nov 01;108(44):E973-8       25 Citations
1Detailed kinetics and regulation of mammalian 2-oxoglutarate dehydrogenase. (Qi F, Pradhan RK, Dash RK, Beard DA) BMC Biochem 2011 Sep 26;12:53       34 Citations
1Discovery and structural characterization of a small molecule 14-3-3 protein-protein interaction inhibitor. (Zhao J, Du Y, Horton JR, Upadhyay AK, Lou B, Bai Y, Zhang X, Du L, Li M, Wang B, Zhang L, Barbieri JT, Khuri FR, Cheng X, Fu H) Proc Natl Acad Sci U S A 2011 Sep 27;108(39):16212-6       94 Citations
2Native-state interconversion of a metamorphic protein requires global unfolding. (Tyler RC, Murray NJ, Peterson FC, Volkman BF) Biochemistry 2011 Aug 23;50(33):7077-9       42 Citations
1Structure of the human histamine H1 receptor complex with doxepin. (Shimamura T, Shiroishi M, Weyand S, Tsujimoto H, Winter G, Katritch V, Abagyan R, Cherezov V, Liu W, Han GW, Kobayashi T, Stevens RC, Iwata S) Nature 2011 Jun 22;475(7354):65-70       708 Citations
1Extracellular disulfide bonds support scavenger receptor class B type I-mediated cholesterol transport. (Papale GA, Hanson PJ, Sahoo D) Biochemistry 2011 Jul 19;50(28):6245-54       26 Citations
1Free energies for coarse-grained proteins by integrating multibody statistical contact potentials with entropies from elastic network models. (Zimmermann MT, Leelananda SP, Gniewek P, Feng Y, Jernigan RL, Kloczkowski A) J Struct Funct Genomics 2011 Jul;12(2):137-47       16 Citations
1Unique ganglioside binding by botulinum neurotoxins C and D-SA. (Kroken AR, Karalewitz AP, Fu Z, Baldwin MR, Kim JJ, Barbieri JT) FEBS J 2011 Dec;278(23):4486-96       23 Citations
1Interaction of nitric oxide with catalase: structural and kinetic analysis. (Purwar N, McGarry JM, Kostera J, Pacheco AA, Schmidt M) Biochemistry 2011 May 31;50(21):4491-503       73 Citations
1Defining CYP3A4 structural responses to substrate binding. Raman spectroscopic studies of a nanodisc-incorporated mammalian cytochrome P450. (Mak PJ, Denisov IG, Grinkova YV, Sligar SG, Kincaid JR) J Am Chem Soc 2011 Feb 09;133(5):1357-66       45 Citations
1Structure of the human dopamine D3 receptor in complex with a D2/D3 selective antagonist. (Chien EY, Liu W, Zhao Q, Katritch V, Han GW, Hanson MA, Shi L, Newman AH, Javitch JA, Cherezov V, Stevens RC) Science 2010 Nov 19;330(6007):1091-5       1015 Citations
1Structural biology: On stress and pressure. (Sigmund CD) Nature 2010 Nov 04;468(7320):46-7       7 Citations
1Structures of the CXCR4 chemokine GPCR with small-molecule and cyclic peptide antagonists. (Wu B, Chien EY, Mol CD, Fenalti G, Liu W, Katritch V, Abagyan R, Brooun A, Wells P, Bi FC, Hamel DJ, Kuhn P, Handel TM, Cherezov V, Stevens RC) Science 2010 Nov 19;330(6007):1066-71       1555 Citations
1Closed headpiece of integrin αIIbβ3 and its complex with an αIIbβ3-specific antagonist that does not induce opening. (Zhu J, Zhu J, Negri A, Provasi D, Filizola M, Coller BS, Springer TA) Blood 2010 Dec 02;116(23):5050-9       100 Citations
1Conformation of dimeric apolipoprotein A-I milano on recombinant lipoprotein particles. (Bhat S, Sorci-Thomas MG, Calabresi L, Samuel MP, Thomas MJ) Biochemistry 2010 Jun 29;49(25):5213-24       17 Citations
1Structural analysis of botulinum neurotoxin type G receptor binding . (Schmitt J, Karalewitz A, Benefield DA, Mushrush DJ, Pruitt RN, Spiller BW, Barbieri JT, Lacy DB) Biochemistry 2010 Jun 29;49(25):5200-5       33 Citations
1Toxins from bacteria. (Henkel JS, Baldwin MR, Barbieri JT) EXS 2010;100:1-29       80 Citations
1Mycobacterium tuberculosis Rv0899 adopts a mixed alpha/beta-structure and does not form a transmembrane beta-barrel. (Teriete P, Yao Y, Kolodzik A, Yu J, Song H, Niederweis M, Marassi FM) Biochemistry 2010 Apr 06;49(13):2768-77       25 Citations
2Targeting biomolecular flexibility with metadynamics. (Leone V, Marinelli F, Carloni P, Parrinello M) Curr Opin Struct Biol 2010 Apr;20(2):148-54       126 Citations
1Defining the structural consequences of mechanism-based inactivation of mammalian cytochrome P450 2B4 using resonance Raman spectroscopy. (Mak PJ, Zhang H, Hollenberg PF, Kincaid JR) J Am Chem Soc 2010 Feb 10;132(5):1494-5       15 Citations
2Rapid, robotic, small-scale protein production for NMR screening and structure determination. (Jensen DR, Woytovich C, Li M, Duvnjak P, Cassidy MS, Frederick RO, Bergeman LF, Peterson FC, Volkman BF) Protein Sci 2010 Mar;19(3):570-8       8 Citations
1Identification of a functionally important loop in Salmonella typhimurium ArnT. (Impellitteri NA, Merten JA, Bretscher LE, Klug CS) Biochemistry 2010 Jan 12;49(1):29-35       8 Citations
2Intermonomer interactions are essential for lysosomal enzyme binding by the cation-dependent mannose 6-phosphate receptor. (Olson LJ, Sun G, Bohnsack RN, Peterson FC, Dahms NM, Kim JJ) Biochemistry 2010 Jan 12;49(1):236-46       8 Citations
1A synergistic small-molecule combination directly eradicates diverse prion strain structures. (Roberts BE, Duennwald ML, Wang H, Chung C, Lopreiato NP, Sweeny EA, Knight MN, Shorter J) Nat Chem Biol 2009 Dec;5(12):936-46       85 Citations
1Carbohydrate recognition by the mannose-6-phosphate receptors. (Kim JJ, Olson LJ, Dahms NM) Curr Opin Struct Biol 2009 Oct;19(5):534-42       64 Citations
1Effects of PKA phosphorylation on the conformation of the Na,K-ATPase regulatory protein FXYD1. (Teriete P, Thai K, Choi J, Marassi FM) Biochim Biophys Acta 2009 Nov;1788(11):2462-70       20 Citations
1Dopamine-induced conformational changes in alpha-synuclein. (Outeiro TF, Klucken J, Bercury K, Tetzlaff J, Putcha P, Oliveira LM, Quintas A, McLean PJ, Hyman BT) PLoS One 2009 Sep 04;4(9):e6906       59 Citations
1Synthesis, structure-affinity relationships, and modeling of AMDA analogs at 5-HT2A and H1 receptors: structural factors contributing to selectivity. (Shah JR, Mosier PD, Roth BL, Kellogg GE, Westkaemper RB) Bioorg Med Chem 2009 Sep 15;17(18):6496-504       21 Citations
1Substrate binding mechanism of HIV-1 protease from explicit-solvent atomistic simulations. (Pietrucci F, Marinelli F, Carloni P, Laio A) J Am Chem Soc 2009 Aug 26;131(33):11811-8       129 Citations
1Inhibition of a viral enzyme by a small-molecule dimer disruptor. (Shahian T, Lee GM, Lazic A, Arnold LA, Velusamy P, Roels CM, Guy RK, Craik CS) Nat Chem Biol 2009 Sep;5(9):640-6       72 Citations
1Focus on molecules: maspin. (Narayan M, Twining S) Exp Eye Res 2010 Jan;90(1):2-3       12 Citations
1Functional role for the conformationally mobile phenylalanine 223 in the reaction of methylenetetrahydrofolate reductase from Escherichia coli. (Lee MN, Takawira D, Nikolova AP, Ballou DP, Furtado VC, Phung NL, Still BR, Thorstad MK, Tanner JJ, Trimmer EE) Biochemistry 2009 Aug 18;48(32):7673-85       17 Citations
2Chapter 3. Lymphotactin structural dynamics. (Volkman BF, Liu TY, Peterson FC) Methods Enzymol 2009;461:51-70       26 Citations
1Glycosylated SV2 and gangliosides as dual receptors for botulinum neurotoxin serotype F. (Fu Z, Chen C, Barbieri JT, Kim JJ, Baldwin MR) Biochemistry 2009 Jun 23;48(24):5631-41       131 Citations
2Structures of two Arabidopsis thaliana major latex proteins represent novel helix-grip folds. (Lytle BL, Song J, de la Cruz NB, Peterson FC, Johnson KA, Bingman CA, Phillips GN Jr, Volkman BF) Proteins 2009 Jul;76(1):237-43       68 Citations
1The major human pregnane X receptor (PXR) splice variant, PXR.2, exhibits significantly diminished ligand-activated transcriptional regulation. (Lin YS, Yasuda K, Assem M, Cline C, Barber J, Li CW, Kholodovych V, Ai N, Chen JD, Welsh WJ, Ekins S, Schuetz EG) Drug Metab Dispos 2009 Jun;37(6):1295-304       35 Citations
1Exploring the folding free energy landscape of insulin using bias exchange metadynamics. (Todorova N, Marinelli F, Piana S, Yarovsky I) J Phys Chem B 2009 Mar 19;113(11):3556-64       42 Citations
1The Center for Eukaryotic Structural Genomics. (Markley JL, Aceti DJ, Bingman CA, Fox BG, Frederick RO, Makino S, Nichols KW, Phillips GN Jr, Primm JG, Sahu SC, Vojtik FC, Volkman BF, Wrobel RL, Zolnai Z) J Struct Funct Genomics 2009 Apr;10(2):165-79       23 Citations
1Pharmacological manipulation of the RAR/RXR signaling pathway maintains the repopulating capacity of hematopoietic stem cells in culture. (Safi R, Muramoto GG, Salter AB, Meadows S, Himburg H, Russell L, Daher P, Doan P, Leibowitz MD, Chao NJ, McDonnell DP, Chute JP) Mol Endocrinol 2009 Feb;23(2):188-201       22 Citations
1Murine NKG2D ligands: "double, double toil and trouble". (Samarakoon A, Chu H, Malarkannan S) Mol Immunol 2009 Mar;46(6):1011-9       38 Citations
1Mapping glycans onto specific N-linked glycosylation sites of Pyrus communis PGIP redefines the interface for EPG-PGIP interactions. (Lim JM, Aoki K, Angel P, Garrison D, King D, Tiemeyer M, Bergmann C, Wells L) J Proteome Res 2009 Feb;8(2):673-80       20 Citations
2HLA-DM mediates epitope selection by a "compare-exchange" mechanism when a potential peptide pool is available. (Ferrante A, Anderson MW, Klug CS, Gorski J) PLoS One 2008;3(11):e3722       28 Citations
2Structural basis of CXCR4 sulfotyrosine recognition by the chemokine SDF-1/CXCL12. (Veldkamp CT, Seibert C, Peterson FC, De la Cruz NB, Haugner JC 3rd, Basnet H, Sakmar TP, Volkman BF) Sci Signal 2008 Sep 16;1(37):ra4       261 Citations
1Kinetic and product distribution analysis of NO* reductase activity in Nitrosomonas europaea hydroxylamine oxidoreductase. (Kostera J, Youngblut MD, Slosarczyk JM, Pacheco AA) J Biol Inorg Chem 2008 Sep;13(7):1073-83       46 Citations
1A model for the solution structure of the rod arrestin tetramer. (Hanson SM, Dawson ES, Francis DJ, Van Eps N, Klug CS, Hubbell WL, Meiler J, Gurevich VV) Structure 2008 Jun;16(6):924-34       67 Citations
1Conformational changes in the metallo-beta-lactamase ImiS during the catalytic reaction: an EPR spectrokinetic study of Co(II)-spin label interactions. (Sharma N, Hu Z, Crowder MW, Bennett B) J Am Chem Soc 2008 Jul 02;130(26):8215-22       18 Citations
1Orientation of the Escherichia coli outer membrane protein OmpX in phospholipid bilayer membranes determined by solid-State NMR. (Mahalakshmi R, Marassi FM) Biochemistry 2008 Jun 24;47(25):6531-8       48 Citations
1Three-dimensional models of HDL apoA-I: implications for its assembly and function. (Thomas MJ, Bhat S, Sorci-Thomas MG) J Lipid Res 2008 Sep;49(9):1875-83       95 Citations
1Catalytic features of the botulinum neurotoxin A light chain revealed by high resolution structure of an inhibitory peptide complex. (Silvaggi NR, Wilson D, Tzipori S, Allen KN) Biochemistry 2008 May 27;47(21):5736-45       55 Citations
1Using structural analysis to generate parasite-selective monoclonal antibodies. (Kron MA, Cichanowicz S, Hendrick A, Liu A, Leykam J, Kuhn LA) Protein Sci 2008 Jun;17(6):983-9       4 Citations
1Structural characterization of the transmembrane domain from subunit e of yeast F1Fo-ATP synthase: a helical GXXXG motif located just under the micelle surface. (Yao H, Stuart RA, Cai S, Sem DS) Biochemistry 2008 Feb 19;47(7):1910-7       10 Citations
1CD36-TSP-HRGP interactions in the regulation of angiogenesis. (Silverstein RL, Febbraio M) Curr Pharm Des 2007;13(35):3559-67       37 Citations
1Galpha-subunits differentially alter the conformation and agonist affinity of kappa-opioid receptors. (Yan F, Mosier PD, Westkaemper RB, Roth BL) Biochemistry 2008 Feb 12;47(6):1567-78       49 Citations
1Binding of serotonin and N1-benzenesulfonyltryptamine-related analogs at human 5-HT6 serotonin receptors: receptor modeling studies. (Dukat M, Mosier PD, Kolanos R, Roth BL, Glennon RA) J Med Chem 2008 Feb 14;51(3):603-11       36 Citations
1Structure of the dual enzyme Ire1 reveals the basis for catalysis and regulation in nonconventional RNA splicing. (Lee KP, Dey M, Neculai D, Cao C, Dever TE, Sicheri F) Cell 2008 Jan 11;132(1):89-100       296 Citations
1Membrane orientation of the Na,K-ATPase regulatory membrane protein CHIF determined by solid-state NMR. (Franzin CM, Teriete P, Marassi FM) Magn Reson Chem 2007 Dec;45 Suppl 1(Suppl 1):S192-7       3 Citations
1Predicting the effect of a point mutation on a protein fold: the villin and advillin headpieces and their Pro62Ala mutants. (Piana S, Laio A, Marinelli F, Van Troys M, Bourry D, Ampe C, Martins JC) J Mol Biol 2008 Jan 11;375(2):460-70       44 Citations
1Interaction between the androgen receptor and a segment of its corepressor SHP. (Jouravel N, Sablin E, Arnold LA, Guy RK, Fletterick RJ) Acta Crystallogr D Biol Crystallogr 2007 Nov;63(Pt 11):1198-200       20 Citations
1Apical membrane targeting and trafficking of the human proton-coupled transporter in polarized epithelia. (Subramanian VS, Marchant JS, Said HM) Am J Physiol Cell Physiol 2008 Jan;294(1):C233-40       41 Citations
1Mapping the specific cytoprotective interaction of humanin with the pro-apoptotic protein bid. (Choi J, Zhai D, Zhou X, Satterthwait A, Reed JC, Marassi FM) Chem Biol Drug Des 2007 Nov;70(5):383-92       18 Citations
1Structural basis of disease-causing mutations in hepatocyte nuclear factor 1beta. (Lu P, Rha GB, Chi YI) Biochemistry 2007 Oct 30;46(43):12071-80       36 Citations
1An unusual transduction pathway in human tonic smooth muscle myosin. (Halstead MF, Ajtai K, Penheiter AR, Spencer JD, Zheng Y, Morrison EA, Burghardt TP) Biophys J 2007 Nov 15;93(10):3555-66       2 Citations
1Modified active site coordination in a clinical mutant of sulfite oxidase. (Doonan CJ, Wilson HL, Rajagopalan KV, Garrett RM, Bennett B, Prince RC, George GN) J Am Chem Soc 2007 Aug 01;129(30):9421-8       28 Citations
1Structural similarity of a membrane protein in micelles and membranes. (Franzin CM, Teriete P, Marassi FM) J Am Chem Soc 2007 Jul 04;129(26):8078-9       47 Citations
1Conformational adaptation of apolipoprotein A-I to discretely sized phospholipid complexes. (Bhat S, Sorci-Thomas MG, Tuladhar R, Samuel MP, Thomas MJ) Biochemistry 2007 Jul 03;46(26):7811-21       65 Citations
1Double-lanthanide-binding tags for macromolecular crystallographic structure determination. (Silvaggi NR, Martin LJ, Schwalbe H, Imperiali B, Allen KN) J Am Chem Soc 2007 Jun 06;129(22):7114-20       75 Citations
1Arrestin mobilizes signaling proteins to the cytoskeleton and redirects their activity. (Hanson SM, Cleghorn WM, Francis DJ, Vishnivetskiy SA, Raman D, Song X, Nair KS, Slepak VZ, Klug CS, Gurevich VV) J Mol Biol 2007 Apr 27;368(2):375-87       115 Citations
2An engineered second disulfide bond restricts lymphotactin/XCL1 to a chemokine-like conformation with XCR1 agonist activity. (Tuinstra RL, Peterson FC, Elgin ES, Pelzek AJ, Volkman BF) Biochemistry 2007 Mar 13;46(10):2564-73       51 Citations
2Multiple WASP-interacting protein recognition motifs are required for a functional interaction with N-WASP. (Peterson FC, Deng Q, Zettl M, Prehoda KE, Lim WA, Way M, Volkman BF) J Biol Chem 2007 Mar 16;282(11):8446-53       42 Citations
1Differential helical orientations among related G protein-coupled receptors provide a novel mechanism for selectivity. Studies with salvinorin A and the kappa-opioid receptor. (Vortherms TA, Mosier PD, Westkaemper RB, Roth BL) J Biol Chem 2007 Feb 02;282(5):3146-56       34 Citations
1Arrestin binding to calmodulin: a direct interaction between two ubiquitous signaling proteins. (Wu N, Hanson SM, Francis DJ, Vishnivetskiy SA, Thibonnier M, Klug CS, Shoham M, Gurevich VV) J Mol Biol 2006 Dec 15;364(5):955-63       72 Citations
1Ca2+-calmodulin and janus kinase 2 are required for activation of sodium-proton exchange by the Gi-coupled 5-hydroxytryptamine 1a receptor. (Turner JH, Garnovskaya MN, Coaxum SD, Vlasova TM, Yakutovich M, Lefler DM, Raymond JR) J Pharmacol Exp Ther 2007 Jan;320(1):314-22       21 Citations
1Characterization of the LSGGQ and H motifs from the Escherichia coli lipid A transporter MsbA. (Buchaklian AH, Klug CS) Biochemistry 2006 Oct 17;45(41):12539-46       29 Citations
1In meso structure of the cobalamin transporter, BtuB, at 1.95 A resolution. (Cherezov V, Yamashita E, Liu W, Zhalnina M, Cramer WA, Caffrey M) J Mol Biol 2006 Dec 08;364(4):716-34       89 Citations
1Structural characterization of mumps virus fusion protein core. (Liu Y, Xu Y, Lou Z, Zhu J, Hu X, Gao GF, Qiu B, Rao Z, Tien P) Biochem Biophys Res Commun 2006 Sep 29;348(3):916-22       13 Citations
1Low frequency resonance Raman spectra of isolated alpha and beta subunits of hemoglobin and their deuterated analogues. (Podstawka E, Mak PJ, Kincaid JR, Proniewicz LM) Biopolymers 2006 Dec 05;83(5):455-66       18 Citations
2Solution structure of Arabidopsis thaliana protein At5g39720.1, a member of the AIG2-like protein family. (Lytle BL, Peterson FC, Tyler EM, Newman CL, Vinarov DA, Markley JL, Volkman BF) Acta Crystallogr Sect F Struct Biol Cryst Commun 2006 Jun 01;62(Pt 6):490-3       7 Citations
1Peptide-membrane interactions and mechanisms of membrane destruction by amphipathic alpha-helical antimicrobial peptides. (Sato H, Feix JB) Biochim Biophys Acta 2006 Sep;1758(9):1245-56       443 Citations
1Discovering new classes of Brugia malayi asparaginyl-tRNA synthetase inhibitors and relating specificity to conformational change. (Sukuru SC, Crepin T, Milev Y, Marsh LC, Hill JB, Anderson RJ, Morris JC, Rohatgi A, O'Mahony G, Grøtli M, Danel F, Page MG, Härtlein M, Cusack S, Kron MA, Kuhn LA) J Comput Aided Mol Des 2006 Mar;20(3):159-78       45 Citations
1EF-G-dependent GTPase on the ribosome. conformational change and fusidic acid inhibition. (Seo HS, Abedin S, Kamp D, Wilson DN, Nierhaus KH, Cooperman BS) Biochemistry 2006 Feb 28;45(8):2504-14       68 Citations
1Visual arrestin binding to microtubules involves a distinct conformational change. (Hanson SM, Francis DJ, Vishnivetskiy SA, Klug CS, Gurevich VV) J Biol Chem 2006 Apr 07;281(14):9765-72       80 Citations
1The anti-angiogenic peptide anginex disrupts the cell membrane. (Pilch J, Franzin CM, Knowles LM, Ferrer FJ, Marassi FM, Ruoslahti E) J Mol Biol 2006 Mar 03;356(4):876-85       17 Citations
1Sir2 protein deacetylases: evidence for chemical intermediates and functions of a conserved histidine. (Smith BC, Denu JM) Biochemistry 2006 Jan 10;45(1):272-82       93 Citations
1Targeting and trafficking of the human thiamine transporter-2 in epithelial cells. (Subramanian VS, Marchant JS, Said HM) J Biol Chem 2006 Feb 24;281(8):5233-45       33 Citations
21H, 15N and 13C resonance assignments of the heme-binding protein murine p22HBP. (Dias JS, Macedo AL, Ferreira GC, Jeanty N, Taketani S, Goodfellow BJ, Peterson FC, Volkman BF) J Biomol NMR 2005 Aug;32(4):338       4 Citations
1Direct observation of protein folding, aggregation, and a prion-like conformational conversion. (Ding F, LaRocque JJ, Dokholyan NV) J Biol Chem 2005 Dec 02;280(48):40235-40       79 Citations
1Mechanistic link between PKR dimerization, autophosphorylation, and eIF2alpha substrate recognition. (Dey M, Cao C, Dar AC, Tamura T, Ozato K, Sicheri F, Dever TE) Cell 2005 Sep 23;122(6):901-13       292 Citations
1Characterization of the antibody response to the receptor binding domain of botulinum neurotoxin serotypes A and E. (Baldwin MR, Tepp WH, Pier CL, Bradshaw M, Ho M, Wilson BA, Fritz RB, Johnson EA, Barbieri JT) Infect Immun 2005 Oct;73(10):6998-7005       58 Citations
1The octarepeat domain of the prion protein binds Cu(II) with three distinct coordination modes at pH 7.4. (Chattopadhyay M, Walter ED, Newell DJ, Jackson PJ, Aronoff-Spencer E, Peisach J, Gerfen GJ, Bennett B, Antholine WE, Millhauser GL) J Am Chem Soc 2005 Sep 14;127(36):12647-56       211 Citations
1Specific conformational changes of plasminogen induced by chloride ions, 6-aminohexanoic acid and benzamidine, but not the overall openness of plasminogen regulate, production of biologically active angiostatins. (Warejcka DJ, Twining SS) Biochem J 2005 Dec 15;392(Pt 3):703-12       10 Citations
2Structure of the B3 domain from Arabidopsis thaliana protein At1g16640. (Waltner JK, Peterson FC, Lytle BL, Volkman BF) Protein Sci 2005 Sep;14(9):2478-83       54 Citations
1Intermolecular contact between globular N-terminal fold and C-terminal domain of ApoA-I stabilizes its lipid-bound conformation: studies employing chemical cross-linking and mass spectrometry. (Bhat S, Sorci-Thomas MG, Alexander ET, Samuel MP, Thomas MJ) J Biol Chem 2005 Sep 23;280(38):33015-25       88 Citations
1Interaction of calmodulin with the serotonin 5-hydroxytryptamine2A receptor. A putative regulator of G protein coupling and receptor phosphorylation by protein kinase C. (Turner JH, Raymond JR) J Biol Chem 2005 Sep 02;280(35):30741-50       58 Citations
2The reaction between nitrite and deoxyhemoglobin. Reassessment of reaction kinetics and stoichiometry. (Huang KT, Keszler A, Patel N, Patel RP, Gladwin MT, Kim-Shapiro DB, Hogg N) J Biol Chem 2005 Sep 02;280(35):31126-31       237 Citations
1Cooperativity during the formation of peptide/MHC class II complexes. (Anderson MW, Gorski J) Biochemistry 2005 Apr 19;44(15):5617-24       24 Citations
1PKR and GCN2 kinases and guanine nucleotide exchange factor eukaryotic translation initiation factor 2B (eIF2B) recognize overlapping surfaces on eIF2alpha. (Dey M, Trieselmann B, Locke EG, Lu J, Cao C, Dar AC, Krishnamoorthy T, Dong J, Sicheri F, Dever TE) Mol Cell Biol 2005 Apr;25(8):3063-75       59 Citations
2Cell-free protein production and labeling protocol for NMR-based structural proteomics. (Vinarov DA, Lytle BL, Peterson FC, Tyler EM, Volkman BF, Markley JL) Nat Methods 2004 Nov;1(2):149-53       120 Citations
1Mechanism of human SIRT1 activation by resveratrol. (Borra MT, Smith BC, Denu JM) J Biol Chem 2005 Apr 29;280(17):17187-95       962 Citations
1Functional analysis of subunit e of the F1Fo-ATP synthase of the yeast Saccharomyces cerevisiae: importance of the N-terminal membrane anchor region. (Everard-Gigot V, Dunn CD, Dolan BM, Brunner S, Jensen RE, Stuart RA) Eukaryot Cell 2005 Feb;4(2):346-55       54 Citations
1Laser photoinitiated nitrosylation of 3-electron reduced Nm europaea hydroxylamine oxidoreductase: kinetic and thermodynamic properties of the nitrosylated enzyme. (Cabail MZ, Kostera J, Pacheco AA) Inorg Chem 2005 Jan 24;44(2):225-31       15 Citations
1The stress or heat shock (HS) response: insights from transgenic mouse models. (Christians ES, Benjamin IJ) Methods 2005 Feb;35(2):170-5       13 Citations
1EPR and X-ray crystallographic characterization of the product-bound form of the MnII-loaded methionyl aminopeptidase from Pyrococcus furiosus. (Copik AJ, Nocek BP, Swierczek SI, Ruebush S, Jang SB, Meng L, D'souza VM, Peters JW, Bennett B, Holz RC) Biochemistry 2005 Jan 11;44(1):121-9       21 Citations
1Crystal structures of complexes between the R61 DD-peptidase and peptidoglycan-mimetic beta-lactams: a non-covalent complex with a "perfect penicillin". (Silvaggi NR, Josephine HR, Kuzin AP, Nagarajan R, Pratt RF, Kelly JA) J Mol Biol 2005 Jan 21;345(3):521-33       50 Citations
1Electrostatic analysis of the hepatitis C virus NS3 helicase reveals both active and allosteric site locations. (Frick DN, Rypma RS, Lam AM, Frenz CM) Nucleic Acids Res 2004;32(18):5519-28       31 Citations
1A phenylalanine zipper mediates APS dimerization. (Dhe-Paganon S, Werner ED, Nishi M, Hansen L, Chi YI, Shoelson SE) Nat Struct Mol Biol 2004 Oct;11(10):968-74       52 Citations
1Pseudomonas aeruginosa ExoS and ExoT. (Barbieri JT, Sun J) Rev Physiol Biochem Pharmacol 2004;152:79-92       201 Citations
2Solution structure of a ubiquitin-like domain from tubulin-binding cofactor B. (Lytle BL, Peterson FC, Qiu SH, Luo M, Zhao Q, Markley JL, Volkman BF) J Biol Chem 2004 Nov 05;279(45):46787-93       29 Citations
1Biochemical analysis of Angelman syndrome-associated mutations in the E3 ubiquitin ligase E6-associated protein. (Cooper EM, Hudson AW, Amos J, Wagstaff J, Howley PM) J Biol Chem 2004 Sep 24;279(39):41208-17       87 Citations
1Resting state conformation of the MsbA homodimer as studied by site-directed spin labeling. (Buchaklian AH, Funk AL, Klug CS) Biochemistry 2004 Jul 06;43(26):8600-6       33 Citations
1Solution structure of a homodimeric hypothetical protein, At5g22580, a structural genomics target from Arabidopsis thaliana. (Cornilescu G, Cornilescu CC, Zhao Q, Frederick RO, Peterson FC, Thao S, Markley JL) J Biomol NMR 2004 Jul;29(3):387-90       13 Citations
1Toward better antibiotics: crystallographic studies of a novel class of DD-peptidase/beta-lactamase inhibitors. (Silvaggi NR, Kaur K, Adediran SA, Pratt RF, Kelly JA) Biochemistry 2004 Jun 08;43(22):7046-53       18 Citations
1Following the rule: formation of the 6-helix bundle of the fusion core from severe acute respiratory syndrome coronavirus spike protein and identification of potent peptide inhibitors. (Zhu J, Xiao G, Xu Y, Yuan F, Zheng C, Liu Y, Yan H, Cole DK, Bell JI, Rao Z, Tien P, Gao GF) Biochem Biophys Res Commun 2004 Jun 18;319(1):283-8       98 Citations
1Conformation of membrane-associated proapoptotic tBid. (Gong XM, Choi J, Franzin CM, Zhai D, Reed JC, Marassi FM) J Biol Chem 2004 Jul 09;279(28):28954-60       59 Citations
1Maltose-binding protein is open in the catalytic transition state for ATP hydrolysis during maltose transport. (Austermuhle MI, Hall JA, Klug CS, Davidson AL) J Biol Chem 2004 Jul 02;279(27):28243-50       64 Citations
2Cdc42 regulates the Par-6 PDZ domain through an allosteric CRIB-PDZ transition. (Peterson FC, Penkert RR, Volkman BF, Prehoda KE) Mol Cell 2004 Mar 12;13(5):665-76       129 Citations
1Structural basis for HNF-4alpha activation by ligand and coactivator binding. (Duda K, Chi YI, Shoelson SE) J Biol Chem 2004 May 28;279(22):23311-6       68 Citations
1Calmodulin interacts with the third intracellular loop of the serotonin 5-hydroxytryptamine1A receptor at two distinct sites: putative role in receptor phosphorylation by protein kinase C. (Turner JH, Gelasco AK, Raymond JR) J Biol Chem 2004 Apr 23;279(17):17027-37       75 Citations
1Structural studies of apoptosis and ion transport regulatory proteins in membranes. (Franzin CM, Choi J, Zhai D, Reed JC, Marassi FM) Magn Reson Chem 2004 Feb;42(2):172-9       41 Citations
2Identification and characterization of a glycosaminoglycan recognition element of the C chemokine lymphotactin. (Peterson FC, Elgin ES, Nelson TJ, Zhang F, Hoeger TJ, Linhardt RJ, Volkman BF) J Biol Chem 2004 Mar 26;279(13):12598-604       72 Citations
1Membrane binding, structure, and localization of cecropin-mellitin hybrid peptides: a site-directed spin-labeling study. (Bhargava K, Feix JB) Biophys J 2004 Jan;86(1 Pt 1):329-36       61 Citations
1Yeast Oxa1 interacts with mitochondrial ribosomes: the importance of the C-terminal region of Oxa1. (Jia L, Dienhart M, Schramp M, McCauley M, Hell K, Stuart RA) EMBO J 2003 Dec 15;22(24):6438-47       186 Citations
1Two novel conserved motifs in the hepatitis C virus NS3 protein critical for helicase action. (Lam AM, Keeney D, Frick DN) J Biol Chem 2003 Nov 07;278(45):44514-24       55 Citations
1Participation of the S4 voltage sensor in the Mg2+-dependent activation of large conductance (BK) K+ channels. (Hu L, Shi J, Ma Z, Krishnamoorthy G, Sieling F, Zhang G, Horrigan FT, Cui J) Proc Natl Acad Sci U S A 2003 Sep 02;100(18):10488-93       53 Citations
1The NMR solution structure of BeF(3)(-)-activated Spo0F reveals the conformational switch in a phosphorelay system. (Gardino AK, Volkman BF, Cho HS, Lee SY, Wemmer DE, Kern D) J Mol Biol 2003 Aug 01;331(1):245-54       36 Citations
1Sufficiency of the reactive site loop of maspin for induction of cell-matrix adhesion and inhibition of cell invasion. Conversion of ovalbumin to a maspin-like molecule. (Ngamkitidechakul C, Warejcka DJ, Burke JM, O'Brien WJ, Twining SS) J Biol Chem 2003 Aug 22;278(34):31796-806       66 Citations
1Identification and functional characterization of a novel mutation of hepatocyte nuclear factor-1alpha gene in a Korean family with MODY3. (Kim KA, Kang K, Chi YI, Chang I, Lee MK, Kim KW, Shoelson SE, Lee MS) Diabetologia 2003 May;46(5):721-7       23 Citations
1Bicarbonate-dependent peroxidase activity of human Cu,Zn-superoxide dismutase induces covalent aggregation of protein: intermediacy of tryptophan-derived oxidation products. (Zhang H, Andrekopoulos C, Joseph J, Chandran K, Karoui H, Crow JP, Kalyanaraman B) J Biol Chem 2003 Jun 27;278(26):24078-89       105 Citations
1Hydration-optimized oriented phospholipid bilayer samples for solid-state NMR structural studies of membrane proteins. (Marassi FM, Crowell KJ) J Magn Reson 2003 Mar;161(1):64-9       34 Citations
1The conserved cytoplasmic module of the transmembrane chemoreceptor McpC mediates carbohydrate chemotaxis in Bacillus subtilis. (Kristich CJ, Glekas GD, Ordal GW) Mol Microbiol 2003 Mar;47(5):1353-66       32 Citations
1Crystallization and preliminary X-ray crystallographic analysis of the trimer core from measles virus fusion protein. (Zhu J, Ding Y, Gao F, Wu T, Zhang CW, Tien P, Rao Z, Gao GF) Acta Crystallogr D Biol Crystallogr 2003 Mar;59(Pt 3):587-90       11 Citations
1Simultaneous assignment and structure determination of a membrane protein from NMR orientational restraints. (Marassi FM, Opella SJ) Protein Sci 2003 Mar;12(3):403-11       167 Citations
1The crystal structure of phosphonate-inhibited D-Ala-D-Ala peptidase reveals an analogue of a tetrahedral transition state. (Silvaggi NR, Anderson JW, Brinsmade SR, Pratt RF, Kelly JA) Biochemistry 2003 Feb 11;42(5):1199-208       57 Citations
1Expression and characterization of the FXYD ion transport regulators for NMR structural studies in lipid micelles and lipid bilayers. (Crowell KJ, Franzin CM, Koltay A, Lee S, Lucchese AM, Snyder BC, Marassi FM) Biochim Biophys Acta 2003 Jan 31;1645(1):15-21       19 Citations
1Structure determination of membrane proteins by NMR spectroscopy. (Opella SJ, Nevzorov A, Mesleh MF, Marassi FM) Biochem Cell Biol 2002;80(5):597-604       59 Citations
1Deamidation, but not truncation, decreases the urea stability of a lens structural protein, betaB1-crystallin. (Kim YH, Kapfer DM, Boekhorst J, Lubsen NH, Bächinger HP, Shearer TR, David LL, Feix JB, Lampi KJ) Biochemistry 2002 Nov 26;41(47):14076-84       75 Citations
1Structures of two kinetic intermediates reveal species specificity of penicillin-binding proteins. (McDonough MA, Anderson JW, Silvaggi NR, Pratt RF, Knox JR, Kelly JA) J Mol Biol 2002 Sep 06;322(1):111-22       80 Citations
1ApoA-I structure on discs and spheres. Variable helix registry and conformational states. (Li HH, Lyles DS, Pan W, Alexander E, Thomas MJ, Sorci-Thomas MG) J Biol Chem 2002 Oct 18;277(42):39093-101       68 Citations
1Lipid-triggered conformational switch of apolipophorin III helix bundle to an extended helix organization. (Sahoo D, Weers PM, Ryan RO, Narayanaswami V) J Mol Biol 2002 Aug 09;321(2):201-14       70 Citations
1Resonance Raman evidence for protein-induced out-of-plane distortion of the heme prosthetic group of mammalian lactoperoxidase. (Zbylut SD, Kincaid JR) J Am Chem Soc 2002 Jun 12;124(23):6751-8       19 Citations
1Zinc-mediated dimerization and its effect on activity and conformation of staphylococcal enterotoxin type C. (Chi YI, Sadler I, Jablonski LM, Callantine SD, Deobald CF, Stauffacher CV, Bohach GA) J Biol Chem 2002 Jun 21;277(25):22839-46       29 Citations
1Prediction of peptide ion collision cross sections from topological molecular structure and amino acid parameters. (Mosier PD, Counterman AE, Jurs PC, Clemmer DE) Anal Chem 2002 Mar 15;74(6):1360-70       45 Citations
1Structure of the globular tail of nuclear lamin. (Dhe-Paganon S, Werner ED, Chi YI, Shoelson SE) J Biol Chem 2002 May 17;277(20):17381-4       229 Citations
1Refined structure and metal binding site of the kalata B1 peptide. (Skjeldal L, Gran L, Sletten K, Volkman BF) Arch Biochem Biophys 2002 Mar 15;399(2):142-8       69 Citations
1Structural rearrangement of human lymphotactin, a C chemokine, under physiological solution conditions. (Kuloğlu ES, McCaslin DR, Markley JL, Volkman BF) J Biol Chem 2002 May 17;277(20):17863-70       63 Citations
1Twists and turns of the cation-dependent mannose 6-phosphate receptor. Ligand-bound versus ligand-free receptor. (Olson LJ, Zhang J, Dahms NM, Kim JJ) J Biol Chem 2002 Mar 22;277(12):10156-61       42 Citations
1Apolipoprotein A-I alpha -helices 7 and 8 modulate high density lipoprotein subclass distribution. (Reschly EJ, Sorci-Thomas MG, Davidson WS, Meredith SC, Reardon CA, Getz GS) J Biol Chem 2002 Mar 22;277(12):9645-54       37 Citations
1A polyalanine-based peptide cannot form a stable transmembrane alpha-helix in fully hydrated phospholipid bilayers. (Lewis RN, Zhang YP, Hodges RS, Subczynski WK, Kusumi A, Flach CR, Mendelsohn R, McElhaney RN) Biochemistry 2001 Oct 09;40(40):12103-11       37 Citations
1Calcium-sensitive regions of GCAP1 as observed by chemical modifications, fluorescence, and EPR spectroscopies. (Sokal I, Li N, Klug CS, Filipek S, Hubbell WL, Baehr W, Palczewski K) J Biol Chem 2001 Nov 16;276(46):43361-73       36 Citations
1AMPA receptor trafficking and the control of synaptic transmission. (Sheng M, Lee SH) Cell 2001 Jun 29;105(7):825-8       168 Citations
1Two-state allosteric behavior in a single-domain signaling protein. (Volkman BF, Lipson D, Wemmer DE, Kern D) Science 2001 Mar 23;291(5512):2429-33       554 Citations
1Platelet activation by a relapsing fever spirochaete results in enhanced bacterium-platelet interaction via integrin alphaIIbbeta3 activation. (Alugupalli KR, Michelson AD, Barnard MR, Robbins D, Coburn J, Baker EK, Ginsberg MH, Schwan TG, Leong JM) Mol Microbiol 2001 Jan;39(2):330-40       40 Citations
1Formation of a noncovalent serpin-proteinase complex involves no conformational change in the serpin. Use of 1H-15N HSQC NMR as a sensitive nonperturbing monitor of conformation. (Peterson FC, Gordon NC, Gettins PG) Biochemistry 2000 Oct 03;39(39):11884-92       35 Citations
1Structural determination of lipid-bound ApoA-I using fluorescence resonance energy transfer. (Li H, Lyles DS, Thomas MJ, Pan W, Sorci-Thomas MG) J Biol Chem 2000 Nov 24;275(47):37048-54       85 Citations
1X-ray structure of a truncated form of cytochrome f from chlamydomonas reinhardtii. (Chi YI, Huang LS, Zhang Z, Fernández-Velasco JG, Berry EA) Biochemistry 2000 Jul 04;39(26):7689-701       45 Citations
1Dimethylsulfoxide reductase: an enzyme capable of catalysis with either molybdenum or tungsten at the active site. (Stewart LJ, Bailey S, Bennett B, Charnock JM, Garner CD, McAlpine AS) J Mol Biol 2000 Jun 09;299(3):593-600       100 Citations
1Structure of a transiently phosphorylated switch in bacterial signal transduction. (Kern D, Volkman BF, Luginbühl P, Nohaile MJ, Kustu S, Wemmer DE) Nature 1999 Dec 23-30;402(6764):894-8       175 Citations
1Structural basis for recognition of phosphorylated high mannose oligosaccharides by the cation-dependent mannose 6-phosphate receptor. (Olson LJ, Zhang J, Lee YC, Dahms NM, Kim JJ) J Biol Chem 1999 Oct 15;274(42):29889-96       56 Citations
1Dilute spin-exchange assignment of solid-state NMR spectra of oriented proteins: acetylcholine M2 in bilayers. (Marassi FM, Gesell JJ, Valente AP, Kim Y, Oblatt-Montal M, Montal M, Opella SJ) J Biomol NMR 1999 Jun;14(2):141-8       45 Citations
11-Butaneboronic acid binding to Aeromonas proteolytica aminopeptidase: a case of arrested development. (De Paola CC, Bennett B, Holz RC, Ringe D, Petsko GA) Biochemistry 1999 Jul 13;38(28):9048-53       46 Citations
1NMR solution structure of plastocyanin from the photosynthetic prokaryote, Prochlorothrix hollandica. (Babu CR, Volkman BF, Bullerjahn GS) Biochemistry 1999 Apr 20;38(16):4988-95       33 Citations
1Structures of the M2 channel-lining segments from nicotinic acetylcholine and NMDA receptors by NMR spectroscopy. (Opella SJ, Marassi FM, Gesell JJ, Valente AP, Kim Y, Oblatt-Montal M, Montal M) Nat Struct Biol 1999 Apr;6(4):374-9       304 Citations
1Crystal structure of the beta-glycosidase from the hyperthermophile Thermosphaera aggregans: insights into its activity and thermostability. (Chi YI, Martinez-Cruz LA, Jancarik J, Swanson RV, Robertson DE, Kim SH) FEBS Lett 1999 Feb 26;445(2-3):375-83       79 Citations
1Pseudomonas aeruginosa exoenzyme S, a double ADP-ribosyltransferase, resembles vertebrate mono-ADP-ribosyltransferases. (Ganesan AK, Mende-Mueller L, Selzer J, Barbieri JT) J Biol Chem 1999 Apr 02;274(14):9503-8       32 Citations
1NMR evidence for a conformational adaptation of apolipophorin III upon lipid association. (Wang J, Sahoo D, Sykes BD, Ryan RO) Biochem Cell Biol 1998;76(2-3):276-83       11 Citations
1Novel aspects of tetramer assembly and N-terminal domain structure and function are revealed by recombinant expression of human AMP deaminase isoforms. (Mahnke-Zizelman DK, Tullson PC, Sabina RL) J Biol Chem 1998 Dec 25;273(52):35118-25       31 Citations
1NMR structural studies of membrane proteins. (Marassi FM, Opella SJ) Curr Opin Struct Biol 1998 Oct;8(5):640-8       140 Citations
1An antibody from a patient with ranitidine-induced thrombocytopenia recognizes a site on glycoprotein IX that is a favored target for drug-induced antibodies. (Gentilini G, Curtis BR, Aster RH) Blood 1998 Oct 01;92(7):2359-65       51 Citations
1Rapid activation and partial inactivation of inositol trisphosphate receptors by inositol trisphosphate. (Marchant JS, Taylor CW) Biochemistry 1998 Aug 18;37(33):11524-33       57 Citations
1Solution structure and backbone dynamics of component IV Glycera dibranchiata monomeric hemoglobin-CO. (Volkman BF, Alam SL, Satterlee JD, Markley JL) Biochemistry 1998 Aug 04;37(31):10906-19       28 Citations
2Ligand-induced conformational change in the ferric enterobactin receptor FepA as studied by site-directed spin labeling and time-domain ESR. (Klug CS, Eaton SS, Eaton GR, Feix JB) Biochemistry 1998 Jun 23;37(25):9016-23       27 Citations
1The hydrophobic face orientation of apolipoprotein A-I amphipathic helix domain 143-164 regulates lecithin:cholesterol acyltransferase activation. (Sorci-Thomas MG, Curtiss L, Parks JS, Thomas MJ, Kearns MW, Landrum M) J Biol Chem 1998 May 08;273(19):11776-82       72 Citations
1Electron transfer by domain movement in cytochrome bc1. (Zhang Z, Huang L, Shulmeister VM, Chi YI, Kim KK, Hung LW, Crofts AR, Berry EA, Kim SH) Nature 1998 Apr 16;392(6677):677-84       980 Citations
1Evidence for oxidation-state-dependent conformational changes in human ferredoxin from multinuclear, multidimensional NMR spectroscopy. (Xia B, Volkman BF, Markley JL) Biochemistry 1998 Mar 17;37(11):3965-73       29 Citations
1Fluorescence studies of exchangeable apolipoprotein-lipid interactions. Superficial association of apolipophorin III with lipoprotein surfaces. (Sahoo D, Narayanaswami V, Kay CM, Ryan RO) J Biol Chem 1998 Jan 16;273(3):1403-8       20 Citations
1Apo structure of the ligand-binding domain of aspartate receptor from Escherichia coli and its comparison with ligand-bound or pseudoligand-bound structures. (Chi YI, Yokota H, Kim SH) FEBS Lett 1997 Sep 08;414(2):327-32       32 Citations
1Ligand-specific opening of a gated-porin channel in the outer membrane of living bacteria. (Jiang X, Payne MA, Cao Z, Foster SB, Feix JB, Newton SM, Klebba PE) Science 1997 May 23;276(5316):1261-4       94 Citations
1Deletion of a single amino acid changes the folding of an apamin hybrid sequence peptide to that of endothelin. (Volkman BF, Wemmer DE) Biopolymers 1997 Apr 05;41(4):451-60       10 Citations
1Solution structure of the quaternary MutT-M2+-AMPCPP-M2+ complex and mechanism of its pyrophosphohydrolase action. (Lin J, Abeygunawardana C, Frick DN, Bessman MJ, Mildvan AS) Biochemistry 1997 Feb 11;36(6):1199-211       83 Citations
1Preferential processing of the S1 subunit of pertussis toxin that is bound to eukaryotic cells. (Finck-Barbançon V, Barbieri JT) Mol Microbiol 1996 Oct;22(1):87-95       5 Citations
1Reconstitution of the [4Fe-4S] cluster in FNR and demonstration of the aerobic-anaerobic transcription switch in vitro. (Green J, Bennett B, Jordan P, Ralph ET, Thomson AJ, Guest JR) Biochem J 1996 Jun 15;316 ( Pt 3)(Pt 3):887-92       161 Citations
1Spectroscopic and kinetic properties of a recombinant form of the flavin domain of spinach NADH: nitrate reductase. (Quinn GB, Trimboli AJ, Prosser IM, Barber MJ) Arch Biochem Biophys 1996 Mar 01;327(1):151-60       15 Citations
1Identification of glutamic acid 381 as a candidate active site residue of Pseudomonas aeruginosa exoenzyme S. (Liu S, Kulich SM, Barbieri JT) Biochemistry 1996 Feb 27;35(8):2754-8       47 Citations
1cDNA sequence of rabbit cardiac titin/connectin. (Greaser ML, Sebestyen MG, Fritz JD, Wolff JA) Adv Biophys 1996;33:13-25       6 Citations
1The staphylococcal and streptococcal pyrogenic toxin family. (Bohach GA, Stauffacher CV, Ohlendorf DH, Chi YI, Vath GM, Schlievert PM) Adv Exp Med Biol 1996;391:131-54       25 Citations
1Solution structure of the MutT enzyme, a nucleoside triphosphate pyrophosphohydrolase. (Abeygunawardana C, Weber DJ, Gittis AG, Frick DN, Lin J, Miller AF, Bessman MJ, Mildvan AS) Biochemistry 1995 Nov 21;34(46):14997-5005       94 Citations
1Mutation of serine 90 to glutamic acid mimics phosphorylation of bovine prolactin. (Maciejewski PM, Peterson FC, Anderson PJ, Brooks CL) J Biol Chem 1995 Nov 17;270(46):27661-5       60 Citations
1Three-dimensional solid-state NMR spectroscopy of a peptide oriented in membrane bilayers. (Ramamoorthy A, Marassi FM, Zasloff M, Opella SJ) J Biomol NMR 1995 Nov;6(3):329-34       75 Citations
1Molecular structure of staphylococcus and streptococcus superantigens. (Schlievert PM, Bohach GA, Ohlendorf DH, Stauffacher CV, Leung DY, Murray DL, Prasad GS, Earhart CA, Jablonski LM, Hoffmann ML, Chi YI) J Clin Immunol 1995 Nov;15(6 Suppl):4S-10S       43 Citations
1Resonance Raman investigation of cyanide ligated beef liver and Aspergillus niger catalases. (al-Mustafa J, Sykora M, Kincaid JR) J Biol Chem 1995 May 05;270(18):10449-60       21 Citations
1NMR studies of the conformations and location of nucleotides bound to the Escherichia coli MutT enzyme. (Frick DN, Weber DJ, Abeygunawardana C, Gittis AG, Bessman MJ, Mildvan AS) Biochemistry 1995 Apr 25;34(16):5577-86       45 Citations
1Structure and dynamics of transient species using time-resolved resonance Raman spectroscopy. (Kincaid JR) Methods Enzymol 1995;246:460-501       19 Citations
1A site-directed spin-labeling study of ligand-induced conformational change in the ferric enterobactin receptor, FepA. (Liu J, Rutz JM, Klebba PE, Feix JB) Biochemistry 1994 Nov 15;33(45):13274-83       48 Citations
1Investigation of the role of the disulphide bond in the activity and structure of staphylococcal enterotoxin C1. (Hovde CJ, Marr JC, Hoffmann ML, Hackett SP, Chi YI, Crum KK, Stevens DL, Stauffacher CV, Bohach GA) Mol Microbiol 1994 Sep;13(5):897-909       83 Citations
1Thiol/disulfide formation associated with the redox activity of the [Fe3S4] cluster of Desulfovibrio gigas ferredoxin II. 1H NMR and Mössbauer spectroscopic study. (Macedo AL, Moura I, Surerus KK, Papaefthymiou V, Liu MY, LeGall J, Münck E, Moura JJ) J Biol Chem 1994 Mar 18;269(11):8052-8       28 Citations
1Resonance Raman study of cyanide-ligated horseradish peroxidase. Detection of two binding geometries and direct evidence for the "push-pull" effect. (al-Mustafa J, Kincaid JR) Biochemistry 1994 Mar 01;33(8):2191-7       45 Citations
1Isolation and sequence analysis of a gene from the linear DNA plasmid pPacl-2 of Pichia acaciae that shows similarity to a killer toxin gene of Kluyveromyces lactis. (Bolen PL, Eastman EM, Cihak PL, Hayman GT) Yeast 1994 Mar;10(3):403-14       22 Citations
1Aggregation state of spin-labeled cecropin AD in solution. (Mchaourab HS, Hyde JS, Feix JB) Biochemistry 1993 Nov 09;32(44):11895-902       35 Citations
2Distinct heme active-site structure in lactoperoxidase revealed by resonance Raman spectroscopy. (Hu S, Treat RW, Kincaid JR) Biochemistry 1993 Sep 28;32(38):10125-30       44 Citations
1Heme active-site structural characterization of chloroperoxidase by resonance Raman spectroscopy. (Hu S, Kincaid JR) J Biol Chem 1993 Mar 25;268(9):6189-93       45 Citations
1Differential effect of polymorphism at HLA-DR1 beta-chain positions 85 and 86 on binding and recognition of DR1-restricted antigenic peptides. (Newton-Nash DK, Eckels DD) J Immunol 1993 Mar 01;150(5):1813-21       66 Citations
1The reovirus cell attachment protein possesses two independently active trimerization domains: basis of dominant negative effects. (Leone G, Maybaum L, Lee PW) Cell 1992 Oct 30;71(3):479-88       39 Citations
1Reaction of cyanide with cytochrome ba3 from Thermus thermophilus: spectroscopic characterization of the Fe(II)a3-CN.Cu(II)B-CN complex suggests four 14N atoms are coordinated to CuB. (Surerus KK, Oertling WA, Fan C, Gurbiel RJ, Einarsdóttir O, Antholine WE, Dyer RB, Hoffman BM, Woodruff WH, Fee JA) Proc Natl Acad Sci U S A 1992 Apr 15;89(8):3195-9       49 Citations
1Crystallization and preliminary X-ray diffraction analysis of staphylococcal enterotoxin type C. (Bohach GA, Chi YI, Stauffacher CV) Proteins 1992 Apr;13(2):152-7       11 Citations
1Sites in the third intracellular loop of the alpha 2A-adrenergic receptor confer short term agonist-promoted desensitization. Evidence for a receptor kinase-mediated mechanism. (Liggett SB, Ostrowski J, Chesnut LC, Kurose H, Raymond JR, Caron MG, Lefkowitz RJ) J Biol Chem 1992 Mar 05;267(7):4740-6       128 Citations
1Cloning and sequence analysis of a trans-regulatory locus required for exoenzyme S synthesis in Pseudomonas aeruginosa. (Frank DW, Iglewski BH) J Bacteriol 1991 Oct;173(20):6460-8       85 Citations
1Trimerization of the reovirus cell attachment protein (sigma 1) induces conformational changes in sigma 1 necessary for its cell-binding function. (Leone G, Duncan R, Lee PW) Virology 1991 Oct;184(2):758-61       19 Citations
1Biochemical and biophysical characterization of the reovirus cell attachment protein sigma 1: evidence that it is a homotrimer. (Strong JE, Leone G, Duncan R, Sharma RK, Lee PW) Virology 1991 Sep;184(1):23-32       64 Citations
1Enhanced hematopoietic activity of a human granulocyte/macrophage colony-stimulating factor-interleukin 3 fusion protein. (Curtis BM, Williams DE, Broxmeyer HE, Dunn J, Farrah T, Jeffery E, Clevenger W, deRoos P, Martin U, Friend D) Proc Natl Acad Sci U S A 1991 Jul 01;88(13):5809-13       146 Citations
1Conformational and functional analysis of the C-terminal globular head of the reovirus cell attachment protein. (Duncan R, Horne D, Strong JE, Leone G, Pon RT, Yeung MC, Lee PW) Virology 1991 Jun;182(2):810-9       38 Citations
1Antibodies that neutralize human beta interferon biologic activity recognize a linear epitope: analysis by synthetic peptide mapping. (Redlich PN, Hoeprich PD Jr, Colby CB, Grossberg SE) Proc Natl Acad Sci U S A 1991 May 01;88(9):4040-4       40 Citations
1Response of phosphatidylcholine in the gel and liquid-crystalline states to membrane surface charges. (Macdonald PM, Leisen J, Marassi FM) Biochemistry 1991 Apr 09;30(14):3558-66       70 Citations
1Neutralizing epitopes of human parainfluenza virus type 3 are conformational and cannot be imitated by synthetic peptides. (Henrickson KJ, Kingsbury DW, van Wyke Coelingh KL, Naeve CW, Portner A) Vaccine 1991 Apr;9(4):243-9       15 Citations
1Experimental and theoretical studies of the three-dimensional structure of human interleukin-4. (Curtis BM, Presnell SR, Srinivasan S, Sassenfeld H, Klinke R, Jeffery E, Cosman D, March CJ, Cohen FE) Proteins 1991;11(2):111-9       37 Citations
1Immunochemical characterization of antigenic domains on human interferon-beta: spatially distinct epitopes are associated with both antiviral and antiproliferative activities. (Redlich PN, Grossberg SE) Eur J Immunol 1990 Sep;20(9):1933-9       12 Citations
1Cloning, sequencing, and expression of a cDNA encoding rat liver mitochondrial carnitine palmitoyltransferase II. (Woeltje KF, Esser V, Weis BC, Sen A, Cox WF, McPhaul MJ, Slaughter CA, Foster DW, McGarry JD) J Biol Chem 1990 Jun 25;265(18):10720-5       113 Citations
1PECAM-1 (CD31) cloning and relation to adhesion molecules of the immunoglobulin gene superfamily. (Newman PJ, Berndt MC, Gorski J, White GC 2nd, Lyman S, Paddock C, Muller WA) Science 1990 Mar 09;247(4947):1219-22       889 Citations
1A novel flagellar Ca2+-binding protein in trypanosomes. (Engman DM, Krause KH, Blumin JH, Kim KS, Kirchhoff LV, Donelson JE) J Biol Chem 1989 Nov 05;264(31):18627-31       94 Citations
1Measurement of rotational molecular motion by time-resolved saturation transfer electron paramagnetic resonance. (Fajer P, Thomas DD, Feix JB, Hyde JS) Biophys J 1986 Dec;50(6):1195-202       22 Citations
1Amino acid sequence of a basic Agkistrodon halys blomhoffii phospholipase A2. Possible role of NH2-terminal lysines in action on phospholipids of Escherichia coli. (Forst S, Weiss J, Blackburn P, Frangione B, Goni F, Elsbach P) Biochemistry 1986 Jul 29;25(15):4309-14       57 Citations
1Evidence that platelet and skeletal sarcoplasmic reticulum Ca2+-ATPase are structurally distinct. (Fischer TH, Campbell KP, White GC 2nd) J Biol Chem 1985 Jul 25;260(15):8996-9001       14 Citations
1Refolding a disulfide dimer of cytochrome c. (Bryant C, Strottmann JM, Stellwagen E) Biochemistry 1985 Jul 02;24(14):3459-64       19 Citations
1A globular high spin form of ferricytochrome c. (Robinson JB Jr, Strottmann JM, Stellwagen E) J Biol Chem 1983 Jun 10;258(11):6772-6       44 Citations
1Induced alterations in the physical state of sialic acid and membrane proteins in human erythrocyte ghosts: implications for the topology of the major sialoglycoprotein. (Butterfield DA, Farmer BT 2nd, Feix JB) Ann N Y Acad Sci 1983;414:169-79       14 Citations
1Differential histone phosphorylation during Drosophila development. (Blumenfeld M, Billings PC, Orf JW, Pan CG, Palmer DK, Snyder LA) Results Probl Cell Differ 1980;11:45-8       1 Citation
1Antibody-combining sites can be mimicked synthetically. Surface-simulation synthesis of the immunoglobulin new combining site to the gamma-hydroxyl derivative of vitamin K1. (Twining SS, Atassi MZ) J Biol Chem 1978 Aug 10;253(15):5259-62       15 Citations