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Publications indexed to the term Transcription Factors

FacultyTitle
3The TRIM33 Bromodomain Recognizes Histone Lysine Lactylation. (Nuñez R, Sidlowski PFW, Steen EA, Wynia-Smith SL, Sprague DJ, Keyes RF, Smith BC) ACS Chem Biol 2024 Dec 20;19(12):2418-2428       1 Citation
1The SWI/SNF subunit ARID1B is important for regenerative ability of hematopoietic stem cells in normal hematopoiesis. (Arnold O, Bluemn T, Stelloh C, Rao S, Zhu N) PLoS One 2024;19(10):e0312616    
4Aberrant PGC-1α signaling in a lamb model of persistent pulmonary hypertension of the newborn. (Mooers EA, Johnson HM, Michalkiewicz T, Rana U, Joshi C, Afolayan AJ, Teng RJ, Konduri GG) Pediatr Res 2024 Dec;96(7):1636-1644    
1CXXC5 drove inflammation and ovarian cancer proliferation via transcriptional activation of ZNF143 and EGR1. (Geng T, Sun Q, He J, Chen Y, Cheng W, Shen J, Liu B, Zhang M, Wang S, Asan K, Song M, Gao Q, Song Y, Liu R, Liu X, Ding Y, Jing A, Ye X, Ren H, Zeng K, Zhou Y, Zhang B, Ma S, Liu W, Liu S, Ji J) Cell Signal 2024 Jul;119:111180       1 Citation
1Recurrent RhoGAP gene fusion CLDN18-ARHGAP26 promotes RHOA activation and focal adhesion kinase and YAP-TEAD signalling in diffuse gastric cancer. (Zhang F, Sahu V, Peng K, Wang Y, Li T, Bala P, Aitymbayev D, Sahgal P, Schaefer A, Der CJ, Ryeom S, Yoon S, Sethi N, Bass AJ, Zhang H) Gut 2024 Jul 11;73(8):1280-1291       3 Citations
4Zinc-chelating BET bromodomain inhibitors equally target islet endocrine cell types. (Jones Lipinski RA, Stancill JS, Nuñez R, Wynia-Smith SL, Sprague DJ, Nord JA, Bird A, Corbett JA, Smith BC) Am J Physiol Regul Integr Comp Physiol 2024 Jun 01;326(6):R515-R527    
2β-Cell-selective regulation of gene expression by nitric oxide. (Naatz A, Yeo CT, Hogg N, Corbett JA) Am J Physiol Regul Integr Comp Physiol 2024 Jun 01;326(6):R552-R566    
2Cancer-associated polybromo-1 bromodomain 4 missense variants variably impact bromodomain ligand binding and cell growth suppression. (Bursch KL, Goetz CJ, Jiao G, Nuñez R, Olp MD, Dhiman A, Khurana M, Zimmermann MT, Urrutia RA, Dykhuizen EC, Smith BC) J Biol Chem 2024 Apr;300(4):107146       2 Citations
1Variants in ZFX are associated with an X-linked neurodevelopmental disorder with recurrent facial gestalt. (Shepherdson JL, Hutchison K, Don DW, McGillivray G, Choi TI, Allan CA, Amor DJ, Banka S, Basel DG, Buch LD, Carere DA, Carroll R, Clayton-Smith J, Crawford A, Dunø M, Faivre L, Gilfillan CP, Gold NB, Gripp KW, Hobson E, Holtz AM, Innes AM, Isidor B, Jackson A, Katsonis P, Amel Riazat Kesh L, Genomics England Research Consortium, Küry S, Lecoquierre F, Lockhart P, Maraval J, Matsumoto N, McCarrier J, McCarthy J, Miyake N, Moey LH, Németh AH, Østergaard E, Patel R, Pope K, Posey JE, Schnur RE, Shaw M, Stolerman E, Taylor JP, Wadman E, Wakeling E, White SM, Wong LC, Lupski JR, Lichtarge O, Corbett MA, Gecz J, Nicolet CM, Farnham PJ, Kim CH, Shinawi M) Am J Hum Genet 2024 Mar 07;111(3):487-508       3 Citations
1Sarcomas Harboring EWSR1::PATZ1 Fusions: A Clinicopathologic Study of 17 Cases. (Dehner CA, Torres-Mora J, Gupta S, Kipp BR, Halling KC, Chen S, Warmke LM, Michal M, Alani A, Yu W, Kovacs K, Obeidin F, Iwenofu OH, Satturwar S, Meis JM, Folpe AL) Mod Pathol 2024 Feb;37(2):100400       7 Citations
1Temporally specific gene expression and chromatin remodeling programs regulate a conserved Pdyn enhancer. (Phillips RA, Wan E, Tuscher JJ, Reid D, Drake OR, Ianov L, Day JJ) Elife 2023 Nov 08;12       3 Citations
2Alternative Genetic Diagnoses in Axenfeld-Rieger Syndrome Spectrum. (Reis LM, Amor DJ, Haddad RA, Nowak CB, Keppler-Noreuil KM, Chisholm SA, Semina EV) Genes (Basel) 2023 Oct 17;14(10)       6 Citations
1CUX1-related neurodevelopmental disorder: deep insights into phenotype-genotype spectrum and underlying pathology. (Oppermann H, Marcos-Grañeda E, Weiss LA, Gurnett CA, Jelsig AM, Vineke SH, Isidor B, Mercier S, Magnussen K, Zacher P, Hashim M, Pagnamenta AT, Race S, Srivastava S, Frazier Z, Maiwald R, Pergande M, Milani D, Rinelli M, Levy J, Krey I, Fontana P, Lonardo F, Riley S, Kretzer J, Rankin J, Reis LM, Semina EV, Reuter MS, Scherer SW, Iascone M, Weis D, Fagerberg CR, Brasch-Andersen C, Hansen LK, Kuechler A, Noble N, Gardham A, Tenney J, Rathore G, Beck-Woedl S, Haack TB, Pavlidou DC, Atallah I, Vodopiutz J, Janecke AR, Hsieh TC, Lesmann H, Klinkhammer H, Krawitz PM, Lemke JR, Jamra RA, Nieto M, Tümer Z, Platzer K) Eur J Hum Genet 2023 Nov;31(11):1251-1260       5 Citations
1Rational Design and Development of Selective BRD7 Bromodomain Inhibitors and Their Activity in Prostate Cancer. (Ordonez-Rubiano SC, Maschinot CA, Wang S, Sood S, Baracaldo-Lancheros LF, Strohmier BP, McQuade AJ, Smith BC, Dykhuizen EC) J Med Chem 2023 Aug 24;66(16):11250-11270       6 Citations
3Loss of PBAF promotes expansion and effector differentiation of CD8+ T cells during chronic viral infection and cancer. (Kharel A, Shen J, Brown R, Chen Y, Nguyen C, Alson D, Bluemn T, Fan J, Gai K, Zhang B, Kudek M, Zhu N, Cui W) Cell Rep 2023 Jun 27;42(6):112649       10 Citations
1Distinct gene expression profiles underlie morphological and etiological differences in pediatric cataracts. (Shanbagh S, Matalia J, Kannan R, Shetty R, Panmand P, Muthu SO, Chaurasia SS, Deshpande V, Bhattacharya SS, Gopalakrishnan AV, Ghosh A) Indian J Ophthalmol 2023 May;71(5):2143-2151       2 Citations
1CenhANCER: a comprehensive cancer enhancer database for primary tissues and cell lines. (Luo ZH, Shi MW, Zhang Y, Wang DY, Tong YB, Pan XL, Cheng S) Database (Oxford) 2023 May 18;2023       3 Citations
1Trajectory reconstruction identifies dysregulation of perinatal maturation programs in pluripotent stem cell-derived cardiomyocytes. (Kannan S, Miyamoto M, Zhu R, Lynott M, Guo J, Chen EZ, Colas AR, Lin BL, Kwon C) Cell Rep 2023 Apr 25;42(4):112330       4 Citations
1ATP-Dependent Chromatin Remodellers in Inner Ear Development. (Chohra I, Chung K, Giri S, Malgrange B) Cells 2023 Feb 07;12(4)       4 Citations
1The small GTPase regulatory protein Rac1 drives podocyte injury independent of cationic channel protein TRPC5. (Polat OK, Isaeva E, Sudhini YR, Knott B, Zhu K, Noben M, Suresh Kumar V, Endlich N, Mangos S, Reddy TV, Samelko B, Wei C, Altintas MM, Dryer SE, Sever S, Staruschenko A, Reiser J) Kidney Int 2023 Jun;103(6):1056-1062       10 Citations
1Diminished motor neuron activity driven by abnormal astrocytic EAAT1 glutamate transporter activity in spinal muscular atrophy is not fully restored after lentiviral SMN delivery. (Welby E, Ebert AD) Glia 2023 May;71(5):1311-1332       5 Citations
1Smarcd3 is an epigenetic modulator of the metabolic landscape in pancreatic ductal adenocarcinoma. (Ferguson LP, Gatchalian J, McDermott ML, Nakamura M, Chambers K, Rajbhandari N, Lytle NK, Rosenthal SB, Hamilton M, Albini S, Wartenberg M, Zlobec I, Galván JA, Karamitopoulou E, Vavinskaya V, Wascher A, Lowy AM, Schürch CM, Puri PL, Bruneau BG, Hargreaves DC, Reya T) Nat Commun 2023 Jan 18;14(1):292       9 Citations
3TCEAL1 loss-of-function results in an X-linked dominant neurodevelopmental syndrome and drives the neurological disease trait in Xq22.2 deletions. (Hijazi H, Reis LM, Pehlivan D, Bernstein JA, Muriello M, Syverson E, Bonner D, Estiar MA, Gan-Or Z, Rouleau GA, Lyulcheva E, Greenhalgh L, Tessarech M, Colin E, Guichet A, Bonneau D, van Jaarsveld RH, Lachmeijer AMA, Ruaud L, Levy J, Tabet AC, Ploski R, Rydzanicz M, Kępczyński Ł, Połatyńska K, Li Y, Fatih JM, Marafi D, Rosenfeld JA, Coban-Akdemir Z, Bi W, Gibbs RA, Hobson GM, Hunter JV, Carvalho CMB, Posey JE, Semina EV, Lupski JR) Am J Hum Genet 2022 Dec 01;109(12):2270-2282       9 Citations
3Selective and Cell-Active PBRM1 Bromodomain Inhibitors Discovered through NMR Fragment Screening. (Shishodia S, Nuñez R, Strohmier BP, Bursch KL, Goetz CJ, Olp MD, Jensen DR, Fenske TG, Ordonez-Rubiano SC, Blau ME, Roach MK, Peterson FC, Volkman BF, Dykhuizen EC, Smith BC) J Med Chem 2022 Oct 27;65(20):13714-13735       14 Citations
4N-terminal BET bromodomain inhibitors disrupt a BRD4-p65 interaction and reduce inducible nitric oxide synthase transcription in pancreatic β-cells. (Nord JA, Wynia-Smith SL, Gehant AL, Jones Lipinski RA, Naatz A, Rioja I, Prinjha RK, Corbett JA, Smith BC) Front Endocrinol (Lausanne) 2022;13:923925       7 Citations
1The druggable transcription factor Fli-1 regulates T cell immunity and tolerance in graft-versus-host disease. (Schutt SD, Wu Y, Kharel A, Bastian D, Choi HJ, Hanief Sofi M, Mealer C, McDaniel Mims B, Nguyen H, Liu C, Helke K, Cui W, Zhang X, Ben-David Y, Yu XZ) J Clin Invest 2022 Nov 01;132(21)       8 Citations
4FOXM1 regulates glycolysis and energy production in multiple myeloma. (Cheng Y, Sun F, Thornton K, Jing X, Dong J, Yun G, Pisano M, Zhan F, Kim SH, Katzenellenbogen JA, Katzenellenbogen BS, Hari P, Janz S) Oncogene 2022 Aug;41(32):3899-3911       27 Citations
1Limitations of mouse models for sickle cell disease conferred by their human globin transgene configurations. (Woodard KJ, Doerfler PA, Mayberry KD, Sharma A, Levine R, Yen J, Valentine V, Palmer LE, Valentine M, Weiss MJ) Dis Model Mech 2022 Jun 01;15(6)       8 Citations
2Combinatorial genetics reveals the Dock1-Rac2 axis as a potential target for the treatment of NPM1;Cohesin mutated AML. (Meyer AE, Stelloh C, Pulakanti K, Burns R, Fisher JB, Heimbruch KE, Tarima S, Furumo Q, Brennan J, Zheng Y, Viny AD, Vassiliou GS, Rao S) Leukemia 2022 Aug;36(8):2032-2041       6 Citations
1Dual function NFI factors control fetal hemoglobin silencing in adult erythroid cells. (Qin K, Huang P, Feng R, Keller CA, Peslak SA, Khandros E, Saari MS, Lan X, Mayuranathan T, Doerfler PA, Abdulmalik O, Giardine B, Chou ST, Shi J, Hardison RC, Weiss MJ, Blobel GA) Nat Genet 2022 Jun;54(6):874-884       22 Citations
1Scalloped Ulcerations in a Tattoo. (Tjahjono L, Chiu YE) J Pediatr 2022 Aug;247:174-175    
1abc4pwm: affinity based clustering for position weight matrices in applications of DNA sequence analysis. (Ali O, Farooq A, Yang M, Jin VX, Bjørås M, Wang J) BMC Bioinformatics 2022 Mar 03;23(1):83       2 Citations
1Post-GWAS functional analysis identifies CUX1 as a regulator of p16INK4a and cellular senescence. (Jiang D, Sun W, Wu T, Zou M, Vasamsetti SB, Zhang X, Zhao Y, Phillippi JA, Sawalha AH, Tavakoli S, Dutta P, Florentin J, Chan SY, Tollison TS, Di Wu, Cui J, Huntress I, Peng X, Finkel T, Li G) Nat Aging 2022 Feb;2(2):140-154    
2Differential roles of BAF and PBAF subunits, Arid1b and Arid2, in MLL-AF9 leukemogenesis. (Bluemn T, Schmitz J, Zheng Y, Burns R, Zheng S, DeJong J, Christiansen L, Arnold O, Izaguirre-Carbonell J, Wang D, Deshpande AJ, Zhu N) Leukemia 2022 Apr;36(4):946-955       11 Citations
1SMARCA4: Implications of an Altered Chromatin-Remodeling Gene for Cancer Development and Therapy. (Mardinian K, Adashek JJ, Botta GP, Kato S, Kurzrock R) Mol Cancer Ther 2021 Dec;20(12):2341-2351       87 Citations
1Targeting ARID1A mutations in cancer. (Mullen J, Kato S, Sicklick JK, Kurzrock R) Cancer Treat Rev 2021 Nov;100:102287       96 Citations
2Multi-omics mapping of human papillomavirus integration sites illuminates novel cervical cancer target genes. (Iden M, Tsaih SW, Huang YW, Liu P, Xiao M, Flister MJ, Rader JS) Br J Cancer 2021 Nov;125(10):1408-1419       14 Citations
1SWI/SNF complex alterations as a biomarker of immunotherapy efficacy in pancreatic cancer. (Botta GP, Kato S, Patel H, Fanta P, Lee S, Okamura R, Kurzrock R) JCI Insight 2021 Sep 22;6(18)       43 Citations
1A protocol for transdifferentiation of human cardiac fibroblasts into endothelial cells via activation of innate immunity. (Liu C, Medina P, Thomas D, Chen IY, Sallam K, Sayed D, Sayed N) STAR Protoc 2021 Jun 18;2(2):100556       2 Citations
1Wedding of Molecular Alterations and Immune Checkpoint Blockade: Genomics as a Matchmaker. (Fountzilas E, Kurzrock R, Vo HH, Tsimberidou AM) J Natl Cancer Inst 2021 Nov 29;113(12):1634-1647       29 Citations
1Role of the Peroxisome Proliferator Activated Receptors in Hypertension. (Fang S, Livergood MC, Nakagawa P, Wu J, Sigmund CD) Circ Res 2021 Apr 02;128(7):1021-1039       33 Citations
1PGC1/PPAR drive cardiomyocyte maturation at single cell level via YAP1 and SF3B2. (Murphy SA, Miyamoto M, Kervadec A, Kannan S, Tampakakis E, Kambhampati S, Lin BL, Paek S, Andersen P, Lee DI, Zhu R, An SS, Kass DA, Uosaki H, Colas AR, Kwon C) Nat Commun 2021 Mar 12;12(1):1648       57 Citations
1Hsp70 acts as a fine-switch that controls E3 ligase CHIP-mediated TAp63 and ΔNp63 ubiquitination and degradation. (Wu HH, Wang B, Armstrong SR, Abuetabh Y, Leng S, Roa WHY, Atfi A, Marchese A, Wilson B, Sergi C, Flores ER, Eisenstat DD, Leng RP) Nucleic Acids Res 2021 Mar 18;49(5):2740-2758       20 Citations
1Targeting oncoproteins with a positive selection assay for protein degraders. (Koduri V, Duplaquet L, Lampson BL, Wang AC, Sabet AH, Ishoey M, Paulk J, Teng M, Harris IS, Endress JE, Liu X, Dasilva E, Paulo JA, Briggs KJ, Doench JG, Ott CJ, Zhang T, Donovan KA, Fischer ES, Gygi SP, Gray NS, Bradner J, Medin JA, Buhrlage SJ, Oser MG, Kaelin WG Jr) Sci Adv 2021 Feb;7(6)       28 Citations
1Evolutionary Conservation of Structural and Functional Coupling between the BRM AT-Hook and Bromodomain. (Lupo BE, Chu P, Harms MJ, Morrison EA, Musselman CA) J Mol Biol 2021 Jul 09;433(14):166845       5 Citations
2Arid2 regulates hematopoietic stem cell differentiation in normal hematopoiesis. (Bluemn T, Schmitz J, Chen Y, Zheng Y, Zhang Y, Zheng S, Burns R, DeJong J, Christiansen L, Izaguirre-Carbonell J, Wang D, Zhu N) Exp Hematol 2021 Feb;94:37-46       12 Citations
1BAP1-Mutated Clear Cell Renal Cell Carcinoma. (Gallan AJ, Parilla M, Segal J, Ritterhouse L, Antic T) Am J Clin Pathol 2021 Apr 26;155(5):718-728       40 Citations
1The rax homeobox gene is mutated in the eyeless axolotl, Ambystoma mexicanum. (Davis ES, Voss G, Miesfeld JB, Zarate-Sanchez J, Voss SR, Glaser T) Dev Dyn 2021 Jun;250(6):807-821       4 Citations
1The Atoh7 remote enhancer provides transcriptional robustness during retinal ganglion cell development. (Miesfeld JB, Ghiasvand NM, Marsh-Armstrong B, Marsh-Armstrong N, Miller EB, Zhang P, Manna SK, Zawadzki RJ, Brown NL, Glaser T) Proc Natl Acad Sci U S A 2020 Sep 01;117(35):21690-21700       28 Citations
3Disruption of foxc1 genes in zebrafish results in dosage-dependent phenotypes overlapping Axenfeld-Rieger syndrome. (Ferre-Fernández JJ, Sorokina EA, Thompson S, Collery RF, Nordquist E, Lincoln J, Semina EV) Hum Mol Genet 2020 Sep 29;29(16):2723-2735       15 Citations
1Tuft Cells Inhibit Pancreatic Tumorigenesis in Mice by Producing Prostaglandin D2. (DelGiorno KE, Chung CY, Vavinskaya V, Maurer HC, Novak SW, Lytle NK, Ma Z, Giraddi RR, Wang D, Fang L, Naeem RF, Andrade LR, Ali WH, Tseng H, Tsui C, Gubbala VB, Ridinger-Saison M, Ohmoto M, Erikson GA, O'Connor C, Shokhirev MN, Hah N, Urade Y, Matsumoto I, Kaech SM, Singh PK, Manor U, Olive KP, Wahl GM) Gastroenterology 2020 Nov;159(5):1866-1881.e8       49 Citations
1Interacting hepatic PAI-1/tPA gene regulatory pathways influence impaired fibrinolysis severity in obesity. (Zheng Z, Nakamura K, Gershbaum S, Wang X, Thomas S, Bessler M, Schrope B, Krikhely A, Liu RM, Ozcan L, López JA, Tabas I) J Clin Invest 2020 Aug 03;130(8):4348-4359       31 Citations
2Core Hippo pathway components act as a brake on Yap and Taz in the development and maintenance of the biliary network. (Brandt ZJ, Echert AE, Bostrom JR, North PN, Link BA) Development 2020 Jun 22;147(12)       8 Citations
2Covalent-Fragment Screening of BRD4 Identifies a Ligandable Site Orthogonal to the Acetyl-Lysine Binding Sites. (Olp MD, Sprague DJ, Goetz CJ, Kathman SG, Wynia-Smith SL, Shishodia S, Summers SB, Xu Z, Statsyuk AV, Smith BC) ACS Chem Biol 2020 Apr 17;15(4):1036-1049       37 Citations
1ARID1A alterations function as a biomarker for longer progression-free survival after anti-PD-1/PD-L1 immunotherapy. (Okamura R, Kato S, Lee S, Jimenez RE, Sicklick JK, Kurzrock R) J Immunother Cancer 2020 Feb;8(1)       131 Citations
1ARID3A and ARID3B induce stem promoting pathways in ovarian cancer cells. (Dausinas P, Pulakanti K, Rao S, Cole JM, Dahl R, Cowden Dahl KD) Gene 2020 May 15;738:144458       20 Citations
2Comparative and Functional Genomic Resource for Mechanistic Studies of Human Blood Pressure-Associated Single Nucleotide Polymorphisms. (Mishra MK, Liang EY, Geurts AM, Auer PWL, Liu P, Rao S, Greene AS, Liang M, Liu Y) Hypertension 2020 Mar;75(3):859-868       16 Citations
3Upstream regulation of the Hippo-Yap pathway in cardiomyocyte regeneration. (Flinn MA, Link BA, O'Meara CC) Semin Cell Dev Biol 2020 Apr;100:11-19       38 Citations
2Cellular reprogramming for successful CNS axon regeneration is driven by a temporally changing cast of transcription factors. (Dhara SP, Rau A, Flister MJ, Recka NM, Laiosa MD, Auer PL, Udvadia AJ) Sci Rep 2019 Oct 02;9(1):14198       28 Citations
2Effects of age-dependent changes in cell size on endothelial cell proliferation and senescence through YAP1. (Mammoto T, Torisawa YS, Muyleart M, Hendee K, Anugwom C, Gutterman D, Mammoto A) Aging (Albany NY) 2019 Sep 05;11(17):7051-7069       22 Citations
2ErbB3-binding protein 1 (EBP1) represses HNF4α-mediated transcription and insulin secretion in pancreatic β-cells. (Han EH, Singh P, Lee IK, Urrutia R, Chi YI) J Biol Chem 2019 Sep 20;294(38):13983-13994       8 Citations
1Genomic Alterations in Undifferentiated Malignant Tumors with Rhabdoid Phenotype and Loss of BRG1 Immunoexpression Identified by Fine Needle Aspirates. (Mei L, Alikhan M, Mujacic I, Parilla M, Antic T) Acta Cytol 2019;63(5):438-444       5 Citations
1Loss of PTEN Accelerates NKX3.1 Degradation to Promote Prostate Cancer Progression. (Bowen C, Ostrowski MC, Leone G, Gelmann EP) Cancer Res 2019 Aug 15;79(16):4124-4134       27 Citations
1A case of Coffin-Siris syndrome with severe congenital heart disease and a novel SMARCA4 variant. (Dsouza NR, Zimmermann MT, Geddes GC) Cold Spring Harb Mol Case Stud 2019 Jun;5(3)       11 Citations
2The Roles of Hippo Signaling Transducers Yap and Taz in Chromatin Remodeling. (Hillmer RE, Link BA) Cells 2019 May 24;8(5)       46 Citations
1Global Transcriptomic Profile Analysis of Genes Involved in Lignin Biosynthesis and Accumulation Induced by Boron Deficiency in Poplar Roots. (Su WL, Liu N, Mei L, Luo J, Zhu YJ, Liang Z) Biomolecules 2019 Apr 19;9(4)       22 Citations
1Encapsulated and solid papillary carcinomas of the breast: Tumors in transition from in situ to invasive? (Solanki MH, Derylo AF, Visotcky AM, Jorns JM) Breast J 2019 May;25(3):539-541       5 Citations
1Temporal dynamic reorganization of 3D chromatin architecture in hormone-induced breast cancer and endocrine resistance. (Zhou Y, Gerrard DL, Wang J, Li T, Yang Y, Fritz AJ, Rajendran M, Fu X, Stein G, Schiff R, Lin S, Frietze S, Jin VX) Nat Commun 2019 Apr 03;10(1):1522       53 Citations
1Eye organogenesis: A hierarchical view of ocular development. (Miesfeld JB, Brown NL) Curr Top Dev Biol 2019;132:351-393       80 Citations
1Dopamine-induced sulfatase and its regulator are required for Salmonella enterica serovar Typhimurium pathogenesis. (Das S, Sreevidya VS, Udvadia AJ, Gyaneshwar P) Microbiology (Reading) 2019 Mar;165(3):302-310       4 Citations
1Genome-Wide Maps of Transcription Regulatory Elements and Transcription Enhancers in Development and Disease. (Agrawal P, Heimbruch KE, Rao S) Compr Physiol 2018 Dec 13;9(1):439-455       14 Citations
1De novo variants in congenital diaphragmatic hernia identify MYRF as a new syndrome and reveal genetic overlaps with other developmental disorders. (Qi H, Yu L, Zhou X, Wynn J, Zhao H, Guo Y, Zhu N, Kitaygorodsky A, Hernan R, Aspelund G, Lim FY, Crombleholme T, Cusick R, Azarow K, Danko ME, Chung D, Warner BW, Mychaliska GB, Potoka D, Wagner AJ, ElFiky M, Wilson JM, Nickerson D, Bamshad M, High FA, Longoni M, Donahoe PK, Chung WK, Shen Y) PLoS Genet 2018 Dec;14(12):e1007822       79 Citations
1An ATF6-tPA pathway in hepatocytes contributes to systemic fibrinolysis and is repressed by DACH1. (Zheng Z, Nayak L, Wang W, Yurdagul A Jr, Wang X, Cai B, Lapping S, Ozcan L, Ramakrishnan R, Pestell RG, Jain MK, Tabas I) Blood 2019 Feb 14;133(7):743-753       24 Citations
2Suppressor mutations reveal an NtrC-like response regulator, NmpR, for modulation of Type-IV Pili-dependent motility in Myxococcus xanthus. (Bretl DJ, Ladd KM, Atkinson SN, Müller S, Kirby JR) PLoS Genet 2018 Oct;14(10):e1007714       6 Citations
1Induction of antiinflammatory purinergic signaling in activated human iNKT cells. (Yu JC, Lin G, Field JJ, Linden J) JCI Insight 2018 Sep 06;3(17)       14 Citations
1Interplay between interferon regulatory factor 1 and BRD4 in the regulation of PD-L1 in pancreatic stellate cells. (Ebine K, Kumar K, Pham TN, Shields MA, Collier KA, Shang M, DeCant BT, Urrutia R, Hwang RF, Grimaldo S, Principe DR, Grippo PJ, Bentrem DJ, Munshi HG) Sci Rep 2018 Sep 05;8(1):13225       33 Citations
2Endothelial YAP1 in Regenerative Lung Growth through the Angiopoietin-Tie2 Pathway. (Mammoto T, Muyleart M, Mammoto A) Am J Respir Cell Mol Biol 2019 Jan;60(1):117-127       29 Citations
1Exome sequencing of 85 Williams-Beuren syndrome cases rules out coding variation as a major contributor to remaining variance in social behavior. (Kopp ND, Parrish PCR, Lugo M, Dougherty JD, Kozel BA) Mol Genet Genomic Med 2018 Sep;6(5):749-765       8 Citations
1CBFβ-SMMHC Inhibition Triggers Apoptosis by Disrupting MYC Chromatin Dynamics in Acute Myeloid Leukemia. (Pulikkan JA, Hegde M, Ahmad HM, Belaghzal H, Illendula A, Yu J, O'Hagan K, Ou J, Muller-Tidow C, Wolfe SA, Zhu LJ, Dekker J, Bushweller JH, Castilla LH) Cell 2018 Jun 28;174(1):172-186.e21       62 Citations
1RitR is an archetype for a novel family of redox sensors in the streptococci that has evolved from two-component response regulators and is required for pneumococcal colonization. (Glanville DG, Han L, Maule AF, Woodacre A, Thanki D, Abdullah IT, Morrissey JA, Clarke TB, Yesilkaya H, Silvaggi NR, Ulijasz AT) PLoS Pathog 2018 May;14(5):e1007052       18 Citations
1Engineering vascularized skeletal muscle tissue with transcriptional factor ETV2-induced autologous endothelial cells. (Yan G, Yan R, Chen C, Chen C, Zhao Y, Qin W, Veldman MB, Li S, Lin S) Protein Cell 2019 Mar;10(3):217-222       9 Citations
2YAP1-TEAD1 signaling controls angiogenesis and mitochondrial biogenesis through PGC1α. (Mammoto A, Muyleart M, Kadlec A, Gutterman D, Mammoto T) Microvasc Res 2018 Sep;119:73-83       44 Citations
1The conformation of the histone H3 tail inhibits association of the BPTF PHD finger with the nucleosome. (Morrison EA, Bowerman S, Sylvers KL, Wereszczynski J, Musselman CA) Elife 2018 Apr 12;7       96 Citations
4PITX2 deficiency and associated human disease: insights from the zebrafish model. (Hendee KE, Sorokina EA, Muheisen SS, Reis LM, Tyler RC, Markovic V, Cuturilo G, Link BA, Semina EV) Hum Mol Genet 2018 May 15;27(10):1675-1695       48 Citations
2Nitric oxide antagonism to glioblastoma photodynamic therapy and mitigation thereof by BET bromodomain inhibitor JQ1. (Fahey JM, Stancill JS, Smith BC, Girotti AW) J Biol Chem 2018 Apr 06;293(14):5345-5359       48 Citations
1Phosphorylation of EZH2 by AMPK Suppresses PRC2 Methyltransferase Activity and Oncogenic Function. (Wan L, Xu K, Wei Y, Zhang J, Han T, Fry C, Zhang Z, Wang YV, Huang L, Yuan M, Xia W, Chang WC, Huang WC, Liu CL, Chang YC, Liu J, Wu Y, Jin VX, Dai X, Guo J, Liu J, Jiang S, Li J, Asara JM, Brown M, Hung MC, Wei W) Mol Cell 2018 Jan 18;69(2):279-291.e5       147 Citations
1Genome variation and conserved regulation identify genomic regions responsible for strain specific phenotypes in rat. (Martín-Gálvez D, Dunoyer de Segonzac D, Ma MCJ, Kwitek AE, Thybert D, Flicek P) BMC Genomics 2017 Dec 22;18(1):986       3 Citations
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1Polyglandular autoimmune syndrome type I - a novel AIRE mutation in a North American patient. (Huibregtse KE, Wolfgram P, Winer KK, Connor EL) J Pediatr Endocrinol Metab 2014 Nov;27(11-12):1257-60       10 Citations
3Single and combinatorial chromatin coupling events underlies the function of transcript factor Krüppel-like factor 11 in the regulation of gene networks. (Calvo E, Grzenda A, Lomberk G, Mathison A, Iovanna J, Urrutia R) BMC Mol Biol 2014 May 25;15:10       6 Citations
1Desmosterol in brain is elevated because DHCR24 needs REST for Robust Expression but REST is poorly expressed. (Tint GS, Pan L, Shang Q, Sharpe LJ, Brown AJ, Li M, Yu H) Dev Neurosci 2014;36(2):132-42       4 Citations
1Mice with an absent stress response are protected against ischemic renal injury. (Sreedharan R, Chen S, Miller M, Haribhai D, Williams CB, Van Why SK) Kidney Int 2014 Sep;86(3):515-24       10 Citations
1Molecular stress-inducing compounds increase osteoclast formation in a heat shock factor 1 protein-dependent manner. (Chai RC, Kouspou MM, Lang BJ, Nguyen CH, van der Kraan AG, Vieusseux JL, Lim RC, Gillespie MT, Benjamin IJ, Quinn JM, Price JT) J Biol Chem 2014 May 09;289(19):13602-14       17 Citations
1Novel and recurrent PITX3 mutations in Belgian families with autosomal dominant congenital cataract and anterior segment dysgenesis have similar phenotypic and functional characteristics. (Verdin H, Sorokina EA, Meire F, Casteels I, de Ravel T, Semina EV, De Baere E) Orphanet J Rare Dis 2014 Feb 20;9:26       29 Citations
1Diabetes-causing gene, kruppel-like factor 11, modulates the antinociceptive response of chronic ethanol intake. (Ou XM, Udemgba C, Wang N, Dai X, Lomberk G, Seo S, Urrutia R, Wang J, Duncan J, Harris S, Fairbanks CA, Zhang X) Alcohol Clin Exp Res 2014 Feb;38(2):401-8       4 Citations
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1Computational analysis reveals a correlation of exon-skipping events with splicing, transcription and epigenetic factors. (Ye Z, Chen Z, Lan X, Hara S, Sunkel B, Huang TH, Elnitski L, Wang Q, Jin VX) Nucleic Acids Res 2014 Mar;42(5):2856-69       24 Citations
1Specificity residues determine binding affinity for two-component signal transduction systems. (Willett JW, Tiwari N, Müller S, Hummels KR, Houtman JC, Fuentes EJ, Kirby JR) mBio 2013 Nov 05;4(6):e00420-13       36 Citations
2Role for Krüppel-like transcription factor 11 in mesenchymal cell function and fibrosis. (Mathison A, Grzenda A, Lomberk G, Velez G, Buttar N, Tietz P, Hendrickson H, Liebl A, Xiong YY, Gores G, Fernandez-Zapico M, Larusso NF, Faubion W, Shah VH, Urrutia R) PLoS One 2013;8(9):e75311       25 Citations
1Functional analysis of HSF4 mutations found in patients with autosomal recessive congenital cataracts. (Merath K, Ronchetti A, Sidjanin DJ) Invest Ophthalmol Vis Sci 2013 Oct 11;54(10):6646-54       13 Citations
1A model for the molecular underpinnings of tooth defects in Axenfeld-Rieger syndrome. (Li X, Venugopalan SR, Cao H, Pinho FO, Paine ML, Snead ML, Semina EV, Amendt BA) Hum Mol Genet 2014 Jan 01;23(1):194-208       23 Citations
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1odd-skipped related 2 is required for fin chondrogenesis in zebrafish. (Lam PY, Kamei CN, Mangos S, Mudumana S, Liu Y, Drummond IA) Dev Dyn 2013 Nov;242(11):1284-92       11 Citations
1Tcf19 is a novel islet factor necessary for proliferation and survival in the INS-1 β-cell line. (Krautkramer KA, Linnemann AK, Fontaine DA, Whillock AL, Harris TW, Schleis GJ, Truchan NA, Marty-Santos L, Lavine JA, Cleaver O, Kimple ME, Davis DB) Am J Physiol Endocrinol Metab 2013 Sep 01;305(5):E600-10       29 Citations
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1MANBA, CXCR5, SOX8, RPS6KB1 and ZBTB46 are genetic risk loci for multiple sclerosis. (International Multiple Sclerosis Genetics Consortium, Lill CM, Schjeide BM, Graetz C, Ban M, Alcina A, Ortiz MA, Pérez J, Damotte V, Booth D, Lopez de Lapuente A, Broer L, Schilling M, Akkad DA, Aktas O, Alloza I, Antigüedad A, Arroyo R, Blaschke P, Buttmann M, Chan A, Compston A, Cournu-Rebeix I, Dörner T, Epplen JT, Fernández Ó, Gerdes LA, Guillot-Noël L, Hartung HP, Hoffjan S, Izquierdo G, Kemppinen A, Kroner A, Kubisch C, Kümpfel T, Li SC, Lindenberger U, Lohse P, Lubetzki C, Luessi F, Malhotra S, Mescheriakova J, Montalban X, Papeix C, Paredes LF, Rieckmann P, Steinhagen-Thiessen E, Winkelmann A, Zettl UK, Hintzen R, Vandenbroeck K, Stewart G, Fontaine B, Comabella M, Urcelay E, Matesanz F, Sawcer S, Bertram L, Zipp F) Brain 2013 Jun;136(Pt 6):1778-82       59 Citations
1Genome-wide expression analysis and EMX2 gene expression in embryonic myoblasts committed to diverse skeletal muscle fiber type fates. (Weimer K, Theobald J, Campbell KS, Esser KA, DiMario JX) Dev Dyn 2013 Aug;242(8):1001-20       6 Citations
1A comprehensive analysis of adiponectin QTLs using SNP association, SNP cis-effects on peripheral blood gene expression and gene expression correlation identified novel metabolic syndrome (MetS) genes with potential role in carcinogenesis and systemic inflammation. (Zhang Y, Kent JW Jr, Olivier M, Ali O, Cerjak D, Broeckel U, Abdou RM, Dyer TD, Comuzzie A, Curran JE, Carless MA, Rainwater DL, Göring HH, Blangero J, Kissebah AH) BMC Med Genomics 2013 Apr 29;6:14       25 Citations
2A novel role of the Sp/KLF transcription factor KLF11 in arresting progression of endometriosis. (Daftary GS, Zheng Y, Tabbaa ZM, Schoolmeester JK, Gada RP, Grzenda AL, Mathison AJ, Keeney GL, Lomberk GA, Urrutia R) PLoS One 2013;8(3):e60165       40 Citations
1Snai1 is important for avian epicardial cell transformation and motility. (Tao G, Miller LJ, Lincoln J) Dev Dyn 2013 Jun;242(6):699-708       12 Citations
1Differential responses of pancreatic β-cells to ROS and RNS. (Meares GP, Fontanilla D, Broniowska KA, Andreone T, Lancaster JR Jr, Corbett JA) Am J Physiol Endocrinol Metab 2013 Mar 15;304(6):E614-22       33 Citations
2Chromosome substitution modulates resistance to ischemia reperfusion injury in Brown Norway rats. (Basile DP, Dwinell MR, Wang SJ, Shames BD, Donohoe DL, Chen S, Sreedharan R, Van Why SK) Kidney Int 2013 Feb;83(2):242-50       20 Citations
1The genetic landscape of mutations in Burkitt lymphoma. (Love C, Sun Z, Jima D, Li G, Zhang J, Miles R, Richards KL, Dunphy CH, Choi WW, Srivastava G, Lugar PL, Rizzieri DA, Lagoo AS, Bernal-Mizrachi L, Mann KP, Flowers CR, Naresh KN, Evens AM, Chadburn A, Gordon LI, Czader MB, Gill JI, Hsi ED, Greenough A, Moffitt AB, McKinney M, Banerjee A, Grubor V, Levy S, Dunson DB, Dave SS) Nat Genet 2012 Dec;44(12):1321-5       492 Citations
3Unfolding of the C-terminal domain of the J-protein Zuo1 releases autoinhibition and activates Pdr1-dependent transcription. (Ducett JK, Peterson FC, Hoover LA, Prunuske AJ, Volkman BF, Craig EA) J Mol Biol 2013 Jan 09;425(1):19-31       33 Citations
1An integrated encyclopedia of DNA elements in the human genome. (ENCODE Project Consortium) Nature 2012 Sep 06;489(7414):57-74       12928 Citations
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1Identification of nephropathy candidate genes by comparing sclerosis-prone and sclerosis-resistant mouse strain kidney transcriptomes. (El-Meanawy A, Schelling JR, Iyengar SK, Hayden P, Barathan S, Goddard K, Pozuelo F, Elashi E, Nair V, Kretzler M, Sedor JR) BMC Nephrol 2012 Jul 19;13:61       7 Citations
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1Integration of Hi-C and ChIP-seq data reveals distinct types of chromatin linkages. (Lan X, Witt H, Katsumura K, Ye Z, Wang Q, Bresnick EH, Farnham PJ, Jin VX) Nucleic Acids Res 2012 Sep;40(16):7690-704       84 Citations
1Mechanistic role for a novel glucocorticoid-KLF11 (TIEG2) protein pathway in stress-induced monoamine oxidase A expression. (Grunewald M, Johnson S, Lu D, Wang Z, Lomberk G, Albert PR, Stockmeier CA, Meyer JH, Urrutia R, Miczek KA, Austin MC, Wang J, Paul IA, Woolverton WL, Seo S, Sittman DB, Ou XM) J Biol Chem 2012 Jul 13;287(29):24195-206       81 Citations
1Effect of exercise on mouse liver and brain bioenergetic infrastructures. (E L, Lu J, Burns JM, Swerdlow RH) Exp Physiol 2013 Jan;98(1):207-19       37 Citations
3PITX2 and FOXC1 spectrum of mutations in ocular syndromes. (Reis LM, Tyler RC, Volkmann Kloss BA, Schilter KF, Levin AV, Lowry RB, Zwijnenburg PJ, Stroh E, Broeckel U, Murray JC, Semina EV) Eur J Hum Genet 2012 Dec;20(12):1224-33       120 Citations
1Interaction with Suv39H1 is critical for Snail-mediated E-cadherin repression in breast cancer. (Dong C, Wu Y, Wang Y, Wang C, Kang T, Rychahou PG, Chi YI, Evers BM, Zhou BP) Oncogene 2013 Mar 14;32(11):1351-62       180 Citations
1Increased mitochondrial biogenesis in muscle improves aging phenotypes in the mtDNA mutator mouse. (Dillon LM, Williams SL, Hida A, Peacock JD, Prolla TA, Lincoln J, Moraes CT) Hum Mol Genet 2012 May 15;21(10):2288-97       80 Citations
1Genetic variation in TRPS1 may regulate hip geometry as well as bone mineral density. (Ackert-Bicknell CL, Demissie S, Tsaih SW, Beamer WG, Cupples LA, Paigen BJ, Hsu YH, Kiel DP, Karasik D) Bone 2012 May;50(5):1188-95       10 Citations
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1Heat shock transcription factor Hsf1 is involved in tumor progression via regulation of hypoxia-inducible factor 1 and RNA-binding protein HuR. (Gabai VL, Meng L, Kim G, Mills TA, Benjamin IJ, Sherman MY) Mol Cell Biol 2012 Mar;32(5):929-40       87 Citations
1Role for the molecular chaperones Zuo1 and Ssz1 in quorum sensing via activation of the transcription factor Pdr1. (Prunuske AJ, Waltner JK, Kuhn P, Gu B, Craig EA) Proc Natl Acad Sci U S A 2012 Jan 10;109(2):472-7       35 Citations
1Loss-of-function thrombospondin-1 mutations in familial pulmonary hypertension. (Maloney JP, Stearman RS, Bull TM, Calabrese DW, Tripp-Addison ML, Wick MJ, Broeckel U, Robbins IM, Wheeler LA, Cogan JD, Loyd JE) Am J Physiol Lung Cell Mol Physiol 2012 Mar 15;302(6):L541-54       40 Citations
1Functional analysis of the Hsf4(lop11) allele responsible for cataracts in lop11 mice. (Liang L, Liegel R, Endres B, Ronchetti A, Chang B, Sidjanin DJ) Mol Vis 2011;17:3062-71       5 Citations
1HSF1-dependent upregulation of Hsp70 by sulfhydryl-reactive inducers of the KEAP1/NRF2/ARE pathway. (Zhang Y, Ahn YH, Benjamin IJ, Honda T, Hicks RJ, Calabrese V, Cole PA, Dinkova-Kostova AT) Chem Biol 2011 Nov 23;18(11):1355-61       96 Citations
1A genome-wide association study identifies new susceptibility loci for non-cardia gastric cancer at 3q13.31 and 5p13.1. (Shi Y, Hu Z, Wu C, Dai J, Li H, Dong J, Wang M, Miao X, Zhou Y, Lu F, Zhang H, Hu L, Jiang Y, Li Z, Chu M, Ma H, Chen J, Jin G, Tan W, Wu T, Zhang Z, Lin D, Shen H) Nat Genet 2011 Oct 30;43(12):1215-8       248 Citations
1VSX2 mutations in autosomal recessive microphthalmia. (Reis LM, Khan A, Kariminejad A, Ebadi F, Tyler RC, Semina EV) Mol Vis 2011;17:2527-32       29 Citations
1Mmp15 is a direct target of Snai1 during endothelial to mesenchymal transformation and endocardial cushion development. (Tao G, Levay AK, Gridley T, Lincoln J) Dev Biol 2011 Nov 15;359(2):209-21       45 Citations
1MAGE I transcription factors regulate KAP1 and KRAB domain zinc finger transcription factor mediated gene repression. (Xiao TZ, Bhatia N, Urrutia R, Lomberk GA, Simpson A, Longley BJ) PLoS One 2011;6(8):e23747       40 Citations
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1A phase 1 dose escalation, pharmacokinetic, and pharmacodynamic evaluation of eIF-4E antisense oligonucleotide LY2275796 in patients with advanced cancer. (Hong DS, Kurzrock R, Oh Y, Wheler J, Naing A, Brail L, Callies S, André V, Kadam SK, Nasir A, Holzer TR, Meric-Bernstam F, Fishman M, Simon G) Clin Cancer Res 2011 Oct 15;17(20):6582-91       112 Citations
1Juvenile dermatomyositis: immunopathogenesis, role of myositis-specific autoantibodies, and review of rituximab use. (Chiu YE, Co DO) Pediatr Dermatol 2011;28(4):357-67       38 Citations
1Using tandem mass spectrometry in targeted mode to identify activators of class IA PI3K in cancer. (Yang X, Turke AB, Qi J, Song Y, Rexer BN, Miller TW, Jänne PA, Arteaga CL, Cantley LC, Engelman JA, Asara JM) Cancer Res 2011 Sep 15;71(18):5965-75       14 Citations
1Genetics of anterior segment dysgenesis disorders. (Reis LM, Semina EV) Curr Opin Ophthalmol 2011 Sep;22(5):314-24       124 Citations
2MIP/Aquaporin 0 represents a direct transcriptional target of PITX3 in the developing lens. (Sorokina EA, Muheisen S, Mlodik N, Semina EV) PLoS One 2011;6(6):e21122       24 Citations
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1Disruption of a novel Kruppel-like transcription factor p300-regulated pathway for insulin biosynthesis revealed by studies of the c.-331 INS mutation found in neonatal diabetes mellitus. (Bonnefond A, Lomberk G, Buttar N, Busiah K, Vaillant E, Lobbens S, Yengo L, Dechaume A, Mignot B, Simon A, Scharfmann R, Neve B, Tanyolaç S, Hodoglugil U, Pattou F, Cavé H, Iovanna J, Stein R, Polak M, Vaxillaire M, Froguel P, Urrutia R) J Biol Chem 2011 Aug 12;286(32):28414-24       68 Citations
1Altered ventilatory and thermoregulatory control in male and female adult Pet-1 null mice. (Hodges MR, Best S, Richerson GB) Respir Physiol Neurobiol 2011 Jul 31;177(2):133-40       40 Citations
1ZNF274 recruits the histone methyltransferase SETDB1 to the 3' ends of ZNF genes. (Frietze S, O'Geen H, Blahnik KR, Jin VX, Farnham PJ) PLoS One 2010 Dec 08;5(12):e15082       126 Citations
1Global analysis of phase locking in gene expression during cell cycle: the potential in network modeling. (Gao S, Hartman JL 4th, Carter JL, Hessner MJ, Wang X) BMC Syst Biol 2010 Dec 03;4:167       8 Citations
5Potential novel mechanism for Axenfeld-Rieger syndrome: deletion of a distant region containing regulatory elements of PITX2. (Volkmann BA, Zinkevich NS, Mustonen A, Schilter KF, Bosenko DV, Reis LM, Broeckel U, Link BA, Semina EV) Invest Ophthalmol Vis Sci 2011 Mar;52(3):1450-9       45 Citations
1Differential roles of Sall4 isoforms in embryonic stem cell pluripotency. (Rao S, Zhen S, Roumiantsev S, McDonald LT, Yuan GC, Orkin SH) Mol Cell Biol 2010 Nov;30(22):5364-80       153 Citations
1Conservation of the TGFbeta/Labial homeobox signaling loop in endoderm-derived cells between Drosophila and mammals. (Lomberk GA, Imoto I, Gebelein B, Urrutia R, Cook TA) Pancreatology 2010;10(1):74-84       3 Citations
1Interaction of Borrelia burgdorferi Hbb with the p66 promoter. (Medrano MS, Policastro PF, Schwan TG, Coburn J) Nucleic Acids Res 2010 Jan;38(2):414-27       18 Citations
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1Febrile-range temperature modifies cytokine gene expression in LPS-stimulated macrophages by differentially modifying NF-{kappa}B recruitment to cytokine gene promoters. (Cooper ZA, Ghosh A, Gupta A, Maity T, Benjamin IJ, Vogel SN, Hasday JD, Singh IS) Am J Physiol Cell Physiol 2010 Jan;298(1):C171-81       34 Citations
1Multiple binding modes between HNF4alpha and the LXXLL motifs of PGC-1alpha lead to full activation. (Rha GB, Wu G, Shoelson SE, Chi YI) J Biol Chem 2009 Dec 11;284(50):35165-76       27 Citations
1Distinct regulation of hepatitis B virus biosynthesis by peroxisome proliferator-activated receptor gamma coactivator 1alpha and small heterodimer partner in human hepatoma cell lines. (Ondracek CR, Reese VC, Rushing CN, Oropeza CE, McLachlan A) J Virol 2009 Dec;83(23):12545-51       17 Citations
2A case of ankyloblepharon, ectodermal dysplasia, and cleft lip/palate syndrome with ectrodactyly: are the p63 syndromes distinct after all? (Chiu YE, Drolet BA, Duffy KJ, Holland KE) Pediatr Dermatol 2011;28(1):15-9       11 Citations
1Peroxisome proliferator-activated receptor gamma Coactivator 1alpha and small heterodimer partner differentially regulate nuclear receptor-dependent hepatitis B virus biosynthesis. (Ondracek CR, Rushing CN, Reese VC, Oropeza CE, McLachlan A) J Virol 2009 Dec;83(23):12535-44       22 Citations
1Dysregulation of the nutrient/stress sensor O-GlcNAcylation is involved in the etiology of cardiovascular disorders, type-2 diabetes and Alzheimer's disease. (Lefebvre T, Dehennaut V, Guinez C, Olivier S, Drougat L, Mir AM, Mortuaire M, Vercoutter-Edouart AS, Michalski JC) Biochim Biophys Acta 2010 Feb;1800(2):67-79       100 Citations
1Genetic analysis of xenocoumacin antibiotic production in the mutualistic bacterium Xenorhabdus nematophila. (Park D, Ciezki K, van der Hoeven R, Singh S, Reimer D, Bode HB, Forst S) Mol Microbiol 2009 Sep;73(5):938-49       71 Citations
1Critical role of ESCRT machinery in EGFR recycling. (Baldys A, Raymond JR) Biochemistry 2009 Oct 13;48(40):9321-3       42 Citations
1Lmx1b is essential for survival of periocular mesenchymal cells and influences Fgf-mediated retinal patterning in zebrafish. (McMahon C, Gestri G, Wilson SW, Link BA) Dev Biol 2009 Aug 15;332(2):287-98       52 Citations
1Intramucosal distribution of WNT signaling components in human esophagus. (Ali I, Rafiee P, Zheng Y, Johnson C, Banerjee B, Haasler G, Jacob H, Shaker R) J Clin Gastroenterol 2009 Apr;43(4):327-37       11 Citations
1Discovery and characterization of novel vascular and hematopoietic genes downstream of etsrp in zebrafish. (Gomez GA, Veldman MB, Zhao Y, Burgess S, Lin S) PLoS One 2009;4(3):e4994       41 Citations
1Primers on molecular pathways--the insulin pathway. (Lomberk G, Urrutia R) Pancreatology 2009;9(3):203-5       5 Citations
1Genomic analysis using high-density single nucleotide polymorphism-based oligonucleotide arrays and multiplex ligation-dependent probe amplification provides a comprehensive analysis of INI1/SMARCB1 in malignant rhabdoid tumors. (Jackson EM, Sievert AJ, Gai X, Hakonarson H, Judkins AR, Tooke L, Perin JC, Xie H, Shaikh TH, Biegel JA) Clin Cancer Res 2009 Mar 15;15(6):1923-30       172 Citations
2A mechanosensitive transcriptional mechanism that controls angiogenesis. (Mammoto A, Connor KM, Mammoto T, Yung CW, Huh D, Aderman CM, Mostoslavsky G, Smith LE, Ingber DE) Nature 2009 Feb 26;457(7233):1103-8       456 Citations
2Investigation of somatic NKX2-5 mutations in congenital heart disease. (Draus JM Jr, Hauck MA, Goetsch M, Austin EH 3rd, Tomita-Mitchell A, Mitchell ME) J Med Genet 2009 Feb;46(2):115-22       59 Citations
1The SWI/SNF chromatin-remodeling complex and glucocorticoid resistance in acute lymphoblastic leukemia. (Pottier N, Yang W, Assem M, Panetta JC, Pei D, Paugh SW, Cheng C, Den Boer ML, Relling MV, Pieters R, Evans WE, Cheok MH) J Natl Cancer Inst 2008 Dec 17;100(24):1792-803       56 Citations
1Anopheles gambiae APL1 is a family of variable LRR proteins required for Rel1-mediated protection from the malaria parasite, Plasmodium berghei. (Riehle MM, Xu J, Lazzaro BP, Rottschaefer SM, Coulibaly B, Sacko M, Niare O, Morlais I, Traore SF, Vernick KD) PLoS One 2008;3(11):e3672       64 Citations
1Interaction between defects in ventilatory and thermoregulatory control in mice lacking 5-HT neurons. (Hodges MR, Richerson GB) Respir Physiol Neurobiol 2008 Dec 31;164(3):350-7       41 Citations
1Endothelial-specific ablation of serum response factor causes hemorrhaging, yolk sac vascular failure, and embryonic lethality. (Holtz ML, Misra RP) BMC Dev Biol 2008 Jun 20;8:65       17 Citations
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2Heterodimer formation of the myeloid zinc finger 1 SCAN domain and association with promyelocytic leukemia nuclear bodies. (Noll L, Peterson FC, Hayes PL, Volkman BF, Sander T) Leuk Res 2008 Oct;32(10):1582-92       27 Citations
1Activation of the constitutive androstane receptor decreases HDL in wild-type and human apoA-I transgenic mice. (Masson D, Qatanani M, Sberna AL, Xiao R, Pais de Barros JP, Grober J, Deckert V, Athias A, Gambert P, Lagrost L, Moore DD, Assem M) J Lipid Res 2008 Aug;49(8):1682-91       37 Citations
1Human cytomegalovirus protein UL38 inhibits host cell stress responses by antagonizing the tuberous sclerosis protein complex. (Moorman NJ, Cristea IM, Terhune SS, Rout MP, Chait BT, Shenk T) Cell Host Microbe 2008 Apr 17;3(4):253-62       174 Citations
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2The solution structure of ZNF593 from Homo sapiens reveals a zinc finger in a predominantly unstructured protein. (Hayes PL, Lytle BL, Volkman BF, Peterson FC) Protein Sci 2008 Mar;17(3):571-6       18 Citations
1Differential display of DNA-binding proteins reveals heat-shock factor 1 as a circadian transcription factor. (Reinke H, Saini C, Fleury-Olela F, Dibner C, Benjamin IJ, Schibler U) Genes Dev 2008 Feb 01;22(3):331-45       191 Citations
1The role of nitric oxide and the unfolded protein response in cytokine-induced beta-cell death. (Chambers KT, Unverferth JA, Weber SM, Wek RC, Urano F, Corbett JA) Diabetes 2008 Jan;57(1):124-32       71 Citations
1Functional analysis of human mutations in homeodomain transcription factor PITX3. (Sakazume S, Sorokina E, Iwamoto Y, Semina EV) BMC Mol Biol 2007 Sep 21;8:84       32 Citations
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1A common polymorphism in the bile acid receptor farnesoid X receptor is associated with decreased hepatic target gene expression. (Marzolini C, Tirona RG, Gervasini G, Poonkuzhali B, Assem M, Lee W, Leake BF, Schuetz JD, Schuetz EG, Kim RB) Mol Endocrinol 2007 Aug;21(8):1769-80       60 Citations
1Mechanisms of synthetic serine protease inhibitor (FUT-175)-mediated cell death. (Uwagawa T, Li Z, Chang Z, Xia Q, Peng B, Sclabas GM, Ishiyama S, Hung MC, Evans DB, Abbruzzese JL, Chiao PJ) Cancer 2007 May 15;109(10):2142-53       42 Citations
1Sox9 is required for precursor cell expansion and extracellular matrix organization during mouse heart valve development. (Lincoln J, Kist R, Scherer G, Yutzey KE) Dev Biol 2007 May 01;305(1):120-32       153 Citations
1Gene expression analysis of gallium-resistant and gallium-sensitive lymphoma cells reveals a role for metal-responsive transcription factor-1, metallothionein-2A, and zinc transporter-1 in modulating the antineoplastic activity of gallium nitrate. (Yang M, Kroft SH, Chitambar CR) Mol Cancer Ther 2007 Feb;6(2):633-43       35 Citations
1Induction of KLF4 in response to heat stress. (Liu Y, Wang J, Yi Y, Zhang H, Liu J, Liu M, Yuan C, Tang D, Benjamin IJ, Xiao X) Cell Stress Chaperones 2006;11(4):379-89       32 Citations
1VEGF is critical for spontaneous differentiation of stem cells into cardiomyocytes. (Song YH, Gehmert S, Sadat S, Pinkernell K, Bai X, Matthias N, Alt E) Biochem Biophys Res Commun 2007 Mar 23;354(4):999-1003       121 Citations
1ADME transcriptome in Hispanic versus White donor livers: evidence of a globally enhanced NR1I3 (CAR, constitutive androstane receptor) gene signature in Hispanics. (Finkelstein D, Lamba V, Assem M, Rengelshausen J, Yasuda K, Strom S, Schuetz E) Xenobiotica 2006;36(10-11):989-1012       12 Citations
1Locating mammalian transcription factor binding sites: a survey of computational and experimental techniques. (Elnitski L, Jin VX, Farnham PJ, Jones SJ) Genome Res 2006 Dec;16(12):1455-64       188 Citations
2Structure of the SCAN domain from the tumor suppressor protein MZF1. (Peterson FC, Hayes PL, Waltner JK, Heisner AK, Jensen DR, Sander TL, Volkman BF) J Mol Biol 2006 Oct 13;363(1):137-47       19 Citations
1Insulin biosynthesis: the IREny of it all. (Corbett JA) Cell Metab 2006 Sep;4(3):175-6       5 Citations
1Multilineage transcriptional priming and determination of alternate hematopoietic cell fates. (Laslo P, Spooner CJ, Warmflash A, Lancki DW, Lee HJ, Sciammas R, Gantner BN, Dinner AR, Singh H) Cell 2006 Aug 25;126(4):755-66       528 Citations
1Differential DNA methylation patterns of small B-cell lymphoma subclasses with different clinical behavior. (Rahmatpanah FB, Carstens S, Guo J, Sjahputera O, Taylor KH, Duff D, Shi H, Davis JW, Hooshmand SI, Chitma-Matsiga R, Caldwell CW) Leukemia 2006 Oct;20(10):1855-62       67 Citations
1Analysis of RNA splicing defects in PITX2 mutants supports a gene dosage model of Axenfeld-Rieger syndrome. (Maciolek NL, Alward WL, Murray JC, Semina EV, McNally MT) BMC Med Genet 2006 Jul 11;7:59       23 Citations
1A mixture model-based discriminate analysis for identifying ordered transcription factor binding site pairs in gene promoters directly regulated by estrogen receptor-alpha. (Li L, Cheng AS, Jin VX, Paik HH, Fan M, Li X, Zhang W, Robarge J, Balch C, Davuluri RV, Kim S, Huang TH, Nephew KP) Bioinformatics 2006 Sep 15;22(18):2210-6       12 Citations
2Human esophageal microvascular endothelial cells respond to acidic pH stress by PI3K/AKT and p38 MAPK-regulated induction of Hsp70 and Hsp27. (Rafiee P, Theriot ME, Nelson VM, Heidemann J, Kanaa Y, Horowitz SA, Rogaczewski A, Johnson CP, Ali I, Shaker R, Binion DG) Am J Physiol Cell Physiol 2006 Nov;291(5):C931-45       79 Citations
1Suz12 binds to silenced regions of the genome in a cell-type-specific manner. (Squazzo SL, O'Geen H, Komashko VM, Krig SR, Jin VX, Jang SW, Margueron R, Reinberg D, Green R, Farnham PJ) Genome Res 2006 Jul;16(7):890-900       275 Citations
1Hearts and bones: shared regulatory mechanisms in heart valve, cartilage, tendon, and bone development. (Lincoln J, Lange AW, Yutzey KE) Dev Biol 2006 Jun 15;294(2):292-302       165 Citations
1Heat shock response: lessons from mouse knockouts. (Christians ES, Benjamin IJ) Handb Exp Pharmacol 2006(172):139-52       27 Citations
1Circadian clockwork machinery in neural retina: evidence for the presence of functional clock components in photoreceptor-enriched chick retinal cell cultures. (Chaurasia SS, Pozdeyev N, Haque R, Visser A, Ivanova TN, Iuvone PM) Mol Vis 2006 Mar 30;12:215-23       37 Citations
1Early transposable element insertion in intron 9 of the Hsf4 gene results in autosomal recessive cataracts in lop11 and ldis1 mice. (Talamas E, Jackson L, Koeberl M, Jackson T, McElwee JL, Hawes NL, Chang B, Jablonski MM, Sidjanin DJ) Genomics 2006 Jul;88(1):44-51       21 Citations
1Combinatorial analysis of transcription factor partners reveals recruitment of c-MYC to estrogen receptor-alpha responsive promoters. (Cheng AS, Jin VX, Fan M, Smith LT, Liyanarachchi S, Yan PS, Leu YW, Chan MW, Plass C, Nephew KP, Davuluri RV, Huang TH) Mol Cell 2006 Feb 03;21(3):393-404       156 Citations
1MPromDb: an integrated resource for annotation and visualization of mammalian gene promoters and ChIP-chip experimental data. (Sun H, Palaniswamy SK, Pohar TT, Jin VX, Huang TH, Davuluri RV) Nucleic Acids Res 2006 Jan 01;34(Database issue):D98-103       35 Citations
1Current molecular understanding of Axenfeld-Rieger syndrome. (Hjalt TA, Semina EV) Expert Rev Mol Med 2005 Nov 08;7(25):1-17       82 Citations
1Heat shock protein-70 mediates the cytoprotective effect of carbon monoxide: involvement of p38 beta MAPK and heat shock factor-1. (Kim HP, Wang X, Zhang J, Suh GY, Benjamin IJ, Ryter SW, Choi AM) J Immunol 2005 Aug 15;175(4):2622-9       131 Citations
1Induction of heat shock proteins by heregulin beta1 leads to protection from apoptosis and anchorage-independent growth. (Khaleque MA, Bharti A, Sawyer D, Gong J, Benjamin IJ, Stevenson MA, Calderwood SK) Oncogene 2005 Sep 29;24(43):6564-73       91 Citations
1Heat shock factor 1-deficient mice exhibit decreased recovery of hearing following noise overstimulation. (Fairfield DA, Lomax MI, Dootz GA, Chen S, Galecki AT, Benjamin IJ, Dolan DF, Altschuler RA) J Neurosci Res 2005 Aug 15;81(4):589-96       36 Citations
1Spi-1 and Spi-B control the expression of the Grap2 gene in B cells. (Garrett-Sinha LA, Hou P, Wang D, Grabiner B, Araujo E, Rao S, Yun TJ, Clark EA, Simon MC, Clark MR) Gene 2005 Jun 20;353(1):134-46       18 Citations
1Recurrent retroviral vector integration at the Mds1/Evi1 locus in nonhuman primate hematopoietic cells. (Calmels B, Ferguson C, Laukkanen MO, Adler R, Faulhaber M, Kim HJ, Sellers S, Hematti P, Schmidt M, von Kalle C, Akagi K, Donahue RE, Dunbar CE) Blood 2005 Oct 01;106(7):2530-3       136 Citations
1Conditional mutagenesis of the murine serum response factor gene blocks cardiogenesis and the transcription of downstream gene targets. (Niu Z, Yu W, Zhang SX, Barron M, Belaguli NS, Schneider MD, Parmacek M, Nordheim A, Schwartz RJ) J Biol Chem 2005 Sep 16;280(37):32531-8       103 Citations
1E2F-8: an E2F family member with a similar organization of DNA-binding domains to E2F-7. (Logan N, Graham A, Zhao X, Fisher R, Maiti B, Leone G, La Thangue NB) Oncogene 2005 Jul 21;24(31):5000-4       106 Citations
1Ssdp1 regulates head morphogenesis of mouse embryos by activating the Lim1-Ldb1 complex. (Nishioka N, Nagano S, Nakayama R, Kiyonari H, Ijiri T, Taniguchi K, Shawlot W, Hayashizaki Y, Westphal H, Behringer RR, Matsuda Y, Sakoda S, Kondoh H, Sasaki H) Development 2005 Jun;132(11):2535-46       60 Citations
1Distinct capacities of individual E2Fs to induce cell cycle re-entry in postmitotic lens fiber cells of transgenic mice. (Chen Q, Liang D, Yang T, Leone G, Overbeek PA) Dev Neurosci 2004;26(5-6):435-45       19 Citations
1Protein kinase C phosphorylation modulates N- and C-terminal regulatory activities of the PITX2 homeodomain protein. (Espinoza HM, Ganga M, Vadlamudi U, Martin DM, Brooks BP, Semina EV, Murray JC, Amendt BA) Biochemistry 2005 Mar 15;44(10):3942-54       26 Citations
1HIF-1alpha, STAT3, CBP/p300 and Ref-1/APE are components of a transcriptional complex that regulates Src-dependent hypoxia-induced expression of VEGF in pancreatic and prostate carcinomas. (Gray MJ, Zhang J, Ellis LM, Semenza GL, Evans DB, Watowich SS, Gallick GE) Oncogene 2005 Apr 28;24(19):3110-20       346 Citations
1Homeodomain revisited: a lesson from disease-causing mutations. (Chi YI) Hum Genet 2005 May;116(6):433-44       61 Citations
1Cloning and characterization of mouse E2F8, a novel mammalian E2F family member capable of blocking cellular proliferation. (Maiti B, Li J, de Bruin A, Gordon F, Timmers C, Opavsky R, Patil K, Tuttle J, Cleghorn W, Leone G) J Biol Chem 2005 May 06;280(18):18211-20       162 Citations
1Mouse HSF1 disruption perturbs redox state and increases mitochondrial oxidative stress in kidney. (Yan LJ, Rajasekaran NS, Sathyanarayanan S, Benjamin IJ) Antioxid Redox Signal 2005;7(3-4):465-71       48 Citations
1Overexpression of tropomysin-related kinase B in metastatic human pancreatic cancer cells. (Sclabas GM, Fujioka S, Schmidt C, Li Z, Frederick WA, Yang W, Yokoi K, Evans DB, Abbruzzese JL, Hess KR, Zhang W, Fidler IJ, Chiao PJ) Clin Cancer Res 2005 Jan 15;11(2 Pt 1):440-9       122 Citations
1Retinoblastoma promotes definitive erythropoiesis by repressing Id2 in fetal liver macrophages. (Iavarone A, King ER, Dai XM, Leone G, Stanley ER, Lasorella A) Nature 2004 Dec 23;432(7020):1040-5       124 Citations
1IFI16 is an essential mediator of growth inhibition, but not differentiation, induced by the leukemia inhibitory factor/JAK/STAT pathway in medullary thyroid carcinoma cells. (Kim EJ, Park JI, Nelkin BD) J Biol Chem 2005 Feb 11;280(6):4913-20       49 Citations
2Using zebrafish to study the complex genetics of glaucoma. (McMahon C, Semina EV, Link BA) Comp Biochem Physiol C Toxicol Pharmacol 2004 Jul;138(3):343-50       53 Citations
1Mutations in PITX2 may contribute to cases of omphalocele and VATER-like syndromes. (Katz LA, Schultz RE, Semina EV, Torfs CP, Krahn KN, Murray JC) Am J Med Genet A 2004 Oct 15;130A(3):277-83       22 Citations
1Treatment with {alpha}-phenyl-N-tert-butylnitrone, a free radical-trapping agent, abrogates inflammatory cytokine gene expression during alloimmune activation in rat cardiac allografts. (Pieper GM, Nilakantan V, Zhou X, Khanna AK, Johnson CP, Roza AM, Adams MB, Hilton G, Felix CC) J Pharmacol Exp Ther 2005 Feb;312(2):774-9       7 Citations
1Statistical modeling for selecting housekeeper genes. (Szabo A, Perou CM, Karaca M, Perreard L, Palais R, Quackenbush JF, Bernard PS) Genome Biol 2004;5(8):R59       163 Citations
1Aberrant regulation of survivin by the RB/E2F family of proteins. (Jiang Y, Saavedra HI, Holloway MP, Leone G, Altura RA) J Biol Chem 2004 Sep 24;279(39):40511-20       151 Citations
1A novel mutation in the PITX2 gene in a family with Axenfeld-Rieger syndrome. (Brooks BP, Moroi SE, Downs CA, Wiltse S, Othman MI, Semina EV, Richards JE) Ophthalmic Genet 2004 Mar;25(1):57-62       26 Citations
1Characterization of Lef-1 promoter segments that facilitate inductive developmental expression in skin. (Liu X, Driskell RR, Luo M, Abbott D, Filali M, Cheng N, Sigmund CD, Engelhardt JF) J Invest Dermatol 2004 Aug;123(2):264-74       29 Citations
1Expression of constitutive androstane receptor splice variants in human tissues and their functional consequences. (Lamba JK, Lamba V, Yasuda K, Lin YS, Assem M, Thompson E, Strom S, Schuetz E) J Pharmacol Exp Ther 2004 Nov;311(2):811-21       92 Citations
1Wnt-responsive element controls Lef-1 promoter expression during submucosal gland morphogenesis. (Driskell RR, Liu X, Luo M, Filali M, Zhou W, Abbott D, Cheng N, Moothart C, Sigmund CD, Engelhardt JF) Am J Physiol Lung Cell Mol Physiol 2004 Oct;287(4):L752-63       32 Citations
1Glucose regulation of insulin gene expression requires the recruitment of p300 by the beta-cell-specific transcription factor Pdx-1. (Mosley AL, Corbett JA, Ozcan S) Mol Endocrinol 2004 Sep;18(9):2279-90       102 Citations
1Integrase-specific enhancement and suppression of retroviral DNA integration by compacted chromatin structure in vitro. (Taganov KD, Cuesta I, Daniel R, Cirillo LA, Katz RA, Zaret KS, Skalka AM) J Virol 2004 Jun;78(11):5848-55       50 Citations
1Gene expression profiling of potential PPARgamma target genes in mouse aorta. (Keen HL, Ryan MJ, Beyer A, Mathur S, Scheetz TE, Gackle BD, Faraci FM, Casavant TL, Sigmund CD) Physiol Genomics 2004 Jun 17;18(1):33-42       44 Citations
1Interactions between hepatic Mrp4 and Sult2a as revealed by the constitutive androstane receptor and Mrp4 knockout mice. (Assem M, Schuetz EG, Leggas M, Sun D, Yasuda K, Reid G, Zelcer N, Adachi M, Strom S, Evans RM, Moore DD, Borst P, Schuetz JD) J Biol Chem 2004 May 21;279(21):22250-7       218 Citations
1Structural basis for HNF-4alpha activation by ligand and coactivator binding. (Duda K, Chi YI, Shoelson SE) J Biol Chem 2004 May 28;279(22):23311-6       69 Citations
1Preparation of defined mononucleosomes, dinucleosomes, and nucleosome arrays in vitro and analysis of transcription factor binding. (Cirillo LA, Zaret KS) Methods Enzymol 2004;375:131-58       8 Citations
1Transforming growth factor-beta1 inhibition of vascular smooth muscle cell activation is mediated via Smad3. (Feinberg MW, Watanabe M, Lebedeva MA, Depina AS, Hanai J, Mammoto T, Frederick JP, Wang XF, Sukhatme VP, Jain MK) J Biol Chem 2004 Apr 16;279(16):16388-93       63 Citations
1[Effects of hsf1 genotype on the constitutive expression of alphaB-crystallin in mice myocardium]. (Liu L, Zhang HH, Ding GX, Cheng YL, Yan LJ, Benjamin IJ) Zhongguo Ying Yong Sheng Li Xue Za Zhi 2004 Feb;20(1):30-3    
1PPAR(gamma) agonist rosiglitazone improves vascular function and lowers blood pressure in hypertensive transgenic mice. (Ryan MJ, Didion SP, Mathur S, Faraci FM, Sigmund CD) Hypertension 2004 Mar;43(3):661-6       176 Citations
1CD36 mediates the phagocytosis of Plasmodium falciparum-infected erythrocytes by rodent macrophages. (Patel SN, Serghides L, Smith TG, Febbraio M, Silverstein RL, Kurtz TW, Pravenec M, Kain KC) J Infect Dis 2004 Jan 15;189(2):204-13       111 Citations
1Evaluation of histogenesis of B-lymphocytes in pediatric EBV-related post-transplant lymphoproliferative disorders. (Abed N, Casper JT, Camitta BM, Margolis D, Trost B, Orentas R, Chang CC) Bone Marrow Transplant 2004 Feb;33(3):321-7       15 Citations
1Reactive oxygen species and molecular regulation of renal oxygenation. (Zou AP, Cowley AW Jr) Acta Physiol Scand 2003 Nov;179(3):233-41       72 Citations
1PPARgamma is not required for the inhibitory actions of PGJ2 on cytokine signaling in pancreatic beta-cells. (Weber SM, Scarim AL, Corbett JA) Am J Physiol Endocrinol Metab 2004 Mar;286(3):E329-36       32 Citations
1Proteolytic release of the carboxy-terminal fragment of proHB-EGF causes nuclear export of PLZF. (Nanba D, Mammoto A, Hashimoto K, Higashiyama S) J Cell Biol 2003 Nov 10;163(3):489-502       140 Citations
1RNA-protein interactions promote asymmetric sorting of the ASH1 mRNA ribonucleoprotein complex. (Gonsalvez GB, Lehmann KA, Ho DK, Stanitsa ES, Williamson JR, Long RM) RNA 2003 Nov;9(11):1383-99       34 Citations
1Use of Hsf1(-/-) mice reveals an essential role for HSF1 to protect lung against cadmium-induced injury. (Wirth D, Christians E, Li X, Benjamin IJ, Gustin P) Toxicol Appl Pharmacol 2003 Oct 01;192(1):12-20       25 Citations
1Regulation of hypoxia-inducible factor-1alpha, vascular endothelial growth factor, and angiogenesis by an insulin-like growth factor-I receptor autocrine loop in human pancreatic cancer. (Stoeltzing O, Liu W, Reinmuth N, Fan F, Parikh AA, Bucana CD, Evans DB, Semenza GL, Ellis LM) Am J Pathol 2003 Sep;163(3):1001-11       148 Citations
1Selective loss of dopaminergic neurons in the substantia nigra of Pitx3-deficient aphakia mice. (Hwang DY, Ardayfio P, Kang UJ, Semina EV, Kim KS) Brain Res Mol Brain Res 2003 Jun 10;114(2):123-31       219 Citations
2Genetic variability at the human FMO1 locus: significance of a basal promoter yin yang 1 element polymorphism (FMO1*6). (Hines RN, Luo Z, Hopp KA, Cabacungan ET, Koukouritaki SB, McCarver DG) J Pharmacol Exp Ther 2003 Sep;306(3):1210-8       39 Citations
1Localized recruitment of a chromatin-remodeling activity by an activator in vivo drives transcriptional elongation. (Corey LL, Weirich CS, Benjamin IJ, Kingston RE) Genes Dev 2003 Jun 01;17(11):1392-401       118 Citations
1Utilizing NMR to study the structure of growth-inhibitory proteins. (Marassi F) Methods Mol Biol 2003;223:3-15    
1Heat shock factor 1-independent activation of dendritic cells by heat shock: implication for the uncoupling of heat-mediated immunoregulation from the heat shock response. (Zheng H, Benjamin IJ, Basu S, Li Z) Eur J Immunol 2003 Jun;33(6):1754-62       29 Citations
1Left and right contributions to the Xenopus heart: implications for asymmetric morphogenesis. (Gormley JP, Nascone-Yoder NM) Dev Genes Evol 2003 Aug;213(8):390-8       23 Citations
1AP-4F, antennapedia peptide linked to an amphipathic alpha helical peptide, increases the efficiency of Lipofectamine-mediated gene transfection in endothelial cells. (Ou J, Geiger T, Ou Z, Ackerman AW, Oldham KT, Pritchard KA Jr) Biochem Biophys Res Commun 2003 Jun 06;305(3):605-10       15 Citations
1Inactivation of E2F3 results in centrosome amplification. (Saavedra HI, Maiti B, Timmers C, Altura R, Tokuyama Y, Fukasawa K, Leone G) Cancer Cell 2003 Apr;3(4):333-46       64 Citations
1Temporal-spatial characterization of chicken clock genes: circadian expression in retina, pineal gland, and peripheral tissues. (Chong NW, Chaurasia SS, Haque R, Klein DC, Iuvone PM) J Neurochem 2003 May;85(4):851-60       66 Citations
1Identification and functional characterization of a novel mutation of hepatocyte nuclear factor-1alpha gene in a Korean family with MODY3. (Kim KA, Kang K, Chi YI, Chang I, Lee MK, Kim KW, Shoelson SE, Lee MS) Diabetologia 2003 May;46(5):721-7       23 Citations
2Mechanisms and implications of platelet discoid shape. (Italiano JE Jr, Bergmeier W, Tiwari S, Falet H, Hartwig JH, Hoffmeister KM, André P, Wagner DD, Shivdasani RA) Blood 2003 Jun 15;101(12):4789-96       141 Citations
2Expression of p53, c-Myc, or Bcl-6 suggests a poor prognosis in primary central nervous system diffuse large B-cell lymphoma among immunocompetent individuals. (Chang CC, Kampalath B, Schultz C, Bunyi-Teopengco E, Logan B, Eshoa C, Dincer AP, Perkins SL) Arch Pathol Lab Med 2003 Feb;127(2):208-12       72 Citations
1Inhibition of IFN-gamma -induced STAT1 activation by 15- deoxy-Delta 12,14-prostaglandin J2. (Weber SM, Scarim AL, Corbett JA) Am J Physiol Endocrinol Metab 2003 May;284(5):E883-91       17 Citations
1CD36-mediated nonopsonic phagocytosis of erythrocytes infected with stage I and IIA gametocytes of Plasmodium falciparum. (Smith TG, Serghides L, Patel SN, Febbraio M, Silverstein RL, Kain KC) Infect Immun 2003 Jan;71(1):393-400       58 Citations
1Diabetes mutations delineate an atypical POU domain in HNF-1alpha. (Chi YI, Frantz JD, Oh BC, Hansen L, Dhe-Paganon S, Shoelson SE) Mol Cell 2002 Nov;10(5):1129-37       89 Citations
1Expression of MUM1/IRF4 correlates with clinical outcome in patients with B-cell chronic lymphocytic leukemia. (Chang CC, Lorek J, Sabath DE, Li Y, Chitambar CR, Logan B, Kampalath B, Cleveland RP) Blood 2002 Dec 15;100(13):4671-5       54 Citations
1Heat shock transcription factor 2 is not essential for embryonic development, fertility, or adult cognitive and psychomotor function in mice. (McMillan DR, Christians E, Forster M, Xiao X, Connell P, Plumier JC, Zuo X, Richardson J, Morgan S, Benjamin IJ) Mol Cell Biol 2002 Nov;22(22):8005-14       66 Citations
1Adrenocortical responses to ACTH in neonatal rats: effect of hypoxia from birth on corticosterone, StAR, and PBR. (Raff H, Hong JJ, Oaks MK, Widmaier EP) Am J Physiol Regul Integr Comp Physiol 2003 Jan;284(1):R78-85       45 Citations
1Mouse heat shock transcription factor 1 deficiency alters cardiac redox homeostasis and increases mitochondrial oxidative damage. (Yan LJ, Christians ES, Liu L, Xiao X, Sohal RS, Benjamin IJ) EMBO J 2002 Oct 01;21(19):5164-72       205 Citations
1Age-related decreases in Nurr1 immunoreactivity in the human substantia nigra. (Chu Y, Kompoliti K, Cochran EJ, Mufson EJ, Kordower JH) J Comp Neurol 2002 Aug 26;450(3):203-14       176 Citations
1Crystal structure of the HNF4 alpha ligand binding domain in complex with endogenous fatty acid ligand. (Dhe-Paganon S, Duda K, Iwamoto M, Chi YI, Shoelson SE) J Biol Chem 2002 Oct 11;277(41):37973-6       248 Citations
1Metabolic adaptation of the fetal and postnatal ovine heart: regulatory role of hypoxia-inducible factors and nuclear respiratory factor-1. (Nau PN, Van Natta T, Ralphe JC, Teneyck CJ, Bedell KA, Caldarone CA, Segar JL, Scholz TD) Pediatr Res 2002 Aug;52(2):269-78       46 Citations
1Exclusion of PITX2 mutations as a major cause of CHARGE association. (Martin DM, Probst FJ, Fox SE, Schimmenti LA, Semina EV, Hefner MA, Belmont JW, Camper SA) Am J Med Genet 2002 Jul 22;111(1):27-30       19 Citations
3Activation of protein kinases in chronically hypoxic infant human and rabbit hearts: role in cardioprotection. (Rafiee P, Shi Y, Kong X, Pritchard KA Jr, Tweddell JS, Litwin SB, Mussatto K, Jaquiss RD, Su J, Baker JE) Circulation 2002 Jul 09;106(2):239-45       82 Citations
1Specificity of E2F1, E2F2, and E2F3 in mediating phenotypes induced by loss of Rb. (Saavedra HI, Wu L, de Bruin A, Timmers C, Rosol TJ, Weinstein M, Robinson ML, Leone G) Cell Growth Differ 2002 May;13(5):215-25       94 Citations
1Exercise, estrogen, and ischemic cardioprotection by heat shock protein 70. (Benjamin IJ, Christians E) Circ Res 2002 May 03;90(8):833-5       19 Citations
1Spi-B can functionally replace PU.1 in myeloid but not lymphoid development. (Dahl R, Ramirez-Bergeron DL, Rao S, Simon MC) EMBO J 2002 May 01;21(9):2220-30       39 Citations
1Differential regulation of gene expression by PITX2 isoforms. (Cox CJ, Espinoza HM, McWilliams B, Chappell K, Morton L, Hjalt TA, Semina EV, Amendt BA) J Biol Chem 2002 Jul 12;277(28):25001-10       142 Citations
1Iron-sulfur cluster biosynthesis: characterization of Schizosaccharomyces pombe Isa1. (Wu G, Mansy SS, Hemann C, Hille R, Surerus KK, Cowan JA) J Biol Inorg Chem 2002 Apr;7(4-5):526-32       69 Citations
1A molecular basis for differential developmental anomalies in Axenfeld-Rieger syndrome. (Espinoza HM, Cox CJ, Semina EV, Amendt BA) Hum Mol Genet 2002 Apr 01;11(7):743-53       57 Citations
1Opening of compacted chromatin by early developmental transcription factors HNF3 (FoxA) and GATA-4. (Cirillo LA, Lin FR, Cuesta I, Friedman D, Jarnik M, Zaret KS) Mol Cell 2002 Feb;9(2):279-89       959 Citations
1Autocrine interleukin-6 production in renal cell carcinoma: evidence for the involvement of p53. (Angelo LS, Talpaz M, Kurzrock R) Cancer Res 2002 Feb 01;62(3):932-40       87 Citations
1Endostatin causes G1 arrest of endothelial cells through inhibition of cyclin D1. (Hanai J, Dhanabal M, Karumanchi SA, Albanese C, Waterman M, Chan B, Ramchandran R, Pestell R, Sukhatme VP) J Biol Chem 2002 May 10;277(19):16464-9       221 Citations
1Heat shock factor 1-mediated thermotolerance prevents cell death and results in G2/M cell cycle arrest. (Luft JC, Benjamin IJ, Mestril R, Dix DJ) Cell Stress Chaperones 2001 Oct;6(4):326-36       48 Citations
1Heat shock factor 1 and heat shock proteins: critical partners in protection against acute cell injury. (Christians ES, Yan LJ, Benjamin IJ) Crit Care Med 2002 Jan;30(1 Suppl):S43-50       191 Citations
1The E2F1-3 transcription factors are essential for cellular proliferation. (Wu L, Timmers C, Maiti B, Saavedra HI, Sang L, Chong GT, Nuckolls F, Giangrande P, Wright FA, Field SJ, Greenberg ME, Orkin S, Nevins JR, Robinson ML, Leone G) Nature 2001 Nov 22;414(6862):457-62       519 Citations
1PU.1/Spi-B regulation of c-rel is essential for mature B cell survival. (Hu CJ, Rao S, Ramirez-Bergeron DL, Garrett-Sinha LA, Gerondakis S, Clark MR, Simon MC) Immunity 2001 Oct;15(4):545-55       42 Citations
1Immunohistochemical expression of cell cycle proteins E2F-1, Cdk-2, Cyclin E, p27(kip1), and Ki-67 in normal placenta and gestational trophoblastic disease. (Olvera M, Harris S, Amezcua CA, McCourty A, Rezk S, Koo C, Felix JC, Brynes RK) Mod Pathol 2001 Oct;14(10):1036-42       43 Citations
1Distal limb malformations: underlying mechanisms and clinical associations. (Sifakis S, Basel D, Ianakiev P, Kilpatrick M, Tsipouras P) Clin Genet 2001 Sep;60(3):165-72       33 Citations
1Critical roles of a cyclic AMP responsive element and an E-box in regulation of mouse renin gene expression. (Pan L, Black TA, Shi Q, Jones CA, Petrovic N, Loudon J, Kane C, Sigmund CD, Gross KW) J Biol Chem 2001 Dec 07;276(49):45530-8       114 Citations
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1Oxygen-dependent expression of hypoxia-inducible factor-1alpha in renal medullary cells of rats. (Zou AP, Yang ZZ, Li PL, Cowley AW JR) Physiol Genomics 2001 Aug 28;6(3):159-68       50 Citations
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