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Balaraman Kalyanaraman PhD

Balaraman Kalyanaraman PhD

Chair, Professor

Institution: Medical College of Wisconsin
Department: Biophysics
Program: Research

Member of the Cancer Center
Member of the Cardiovascular Center
Member of the Neuroscience Research Center


Publications

  • Mitochondria-targeted drugs stimulate mitophagy and abrogate colon cancer cell proliferation. (Boyle KA, Van Wickle J, Hill RB, Marchese A, Kalyanaraman B, Dwinell MB) J Biol Chem 2018 Sep 21;293(38):14891-14904 PMID: 30087121 PMCID: PMC6153299 08/09/2018    
  • Detection of mitochondria-generated reactive oxygen species in cells using multiple probes and methods: Potentials, pitfalls, and the future. (Cheng G, Zielonka M, Dranka B, Kumar SN, Myers CR, Bennett B, Garces AM, Dias Duarte Machado LG, Thiebaut D, Ouari O, Hardy M, Zielonka J, Kalyanaraman B) J Biol Chem 2018 06 29;293(26):10363-10380 PMID: 29739855 PMCID: PMC6028982 05/10/2018       3 Citations
  • Kindlin-3 negatively regulates the release of neutrophil extracellular traps. (Xu Z, Ni B, Cao Z, Zielonka J, Gao J, Chen F, Kalyanaraman B, White GC, Ma YQ) J Leukoc Biol 2018 Sep;104(3):597-602 PMID: 29656482 PMCID: PMC6113072 04/16/2018    
  • Small-molecule luminescent probes for the detection of cellular oxidizing and nitrating species. (Zielonka J, Kalyanaraman B) Free Radic Biol Med 2018 Nov 20;128:3-22 PMID: 29567392 PMCID: PMC6146080 03/24/2018       3 Citations
  • Corrigendum to 'A review of the basics of mitochondrial bioenergetics, metabolism, and related signaling pathways in cancer cells: Therapeutic targeting of tumor mitochondria with lipophilic cationic compounds' [REDOX 14C (2017) 316-327]. (Kalyanaraman B, Cheng G, Hardy M, Ouari O, Lopez M, Joseph J, Zielonka J, Dwinell MB) Redox Biol 2018 06;16:426-427 PMID: 29548725 PMCID: PMC5952812 03/20/2018    
  • Teaching the basics of reactive oxygen species and their relevance to cancer biology: Mitochondrial reactive oxygen species detection, redox signaling, and targeted therapies. (Kalyanaraman B, Cheng G, Hardy M, Ouari O, Bennett B, Zielonka J) Redox Biol 2018 05;15:347-362 PMID: 29306792 PMCID: PMC5756055 01/08/2018       12 Citations
  • Corrigendum to "European contribution to the study of ROS: A summary of the findings and prospects for the future from the COST action BM1203 (EU-ROS)" [Redox Biol. 13 (2017) 94-162]. (Egea J, Fabregat I, Frapart YM, Ghezzi P, Görlach A, Kietzmann T, Kubaichuk K, Knaus UG, Lopez MG, Olaso-Gonzalez G, Petry A, Schulz R, Vina J, Winyard P, Abbas K, Ademowo OS, Afonso CB, Andreadou I, Antelmann H, Antunes F, Aslan M, Bachschmid MM, Barbosa RM, Belousov V, Berndt C, Bernlohr D, Bertrán E, Bindoli A, Bottari SP, Brito PM, Carrara G, Casas AI, Chatzi A, Chondrogianni N, Conrad M, Cooke MS, Costa JG, Cuadrado A, My-Chan Dang P, De Smet B, Debelec-Butuner B, Dias IHK, Dunn JD, Edson AJ, El Assar M, El-Benna J, Ferdinandy P, Fernandes AS, Fladmark KE, Förstermann U, Giniatullin R, Giricz Z, Görbe A, Griffiths H, Hampl V, Hanf A, Herget J, Hernansanz-Agustín P, Hillion M, Huang J, Ilikay S, Jansen-Dürr P, Jaquet V, Joles JA, Kalyanaraman B, Kaminskyy D, Karbaschi M, Kleanthous M, Klotz LO, Korac B, Korkmaz KS, Koziel R, Kračun D, Krause KH, Křen V, Krieg T, Laranjinha J, Lazou A, Li H, Martínez-Ruiz A, Matsui R, McBean GJ, Meredith SP, Messens J, Miguel V, Mikhed Y, Milisav I, Milković L, Miranda-Vizuete A, Mojović M, Monsalve M, Mouthuy PA, Mulvey J, Münzel T, Muzykantov V, Nguyen ITN, Oelze M, Oliveira NG, Palmeira CM, Papaevgeniou N, Pavićević A, Pedre B, Peyrot F, Phylactides M, Pircalabioru GG, Pitt AR, Poulsen HE, Prieto I, Rigobello MP, Robledinos-Antón N, Rodríguez-Mañas L, Rolo AP, Rousset F, Ruskovska T, Saraiva N, Sasson S, Schröder K, Semen K, Seredenina T, Shakirzyanova A, Smith GL, Soldati T, Sousa BC, Spickett CM, Stancic A, Stasia MJ, Steinbrenner H, Stepanić V, Steven S, Tokatlidis K, Tuncay E, Turan B, Ursini F, Vacek J, Vajnerova O, Valentová K, Van Breusegem F, Varisli L, Veal EA, Yalçın AS, Yelisyeyeva O, Žarković N, Zatloukalová M, Zielonka J, Touyz RM, Papapetropoulos A, Grune T, Lamas S, Schmidt HHHW, Di Lisa F, Daiber A) Redox Biol 2018 04;14:694-696 PMID: 29107648 PMCID: PMC5975209 11/07/2017    
  • Unusual Double Beckmann Fragmentation Reaction under Physiological Conditions. (Xie LN, Huang CH, Xu D, Li F, Zhu JG, Shen C, Shao B, Gao HY, Kalyanaraman B, Zhu BZ) J Org Chem 2017 12 15;82(24):13084-13092 PMID: 29096055 11/03/2017       1 Citations
  • Xth EPR Workshop on Applications of EPR in Biology and Medicine. (Sarna T, Kalyanaraman B, Berliner L) Cell Biochem Biophys 2017 12;75(3-4):257-258 PMID: 29071513 PMCID: PMC5691121 10/27/2017    
  • Detection and Characterization of Reactive Oxygen and Nitrogen Species in Biological Systems by Monitoring Species-Specific Products. (Hardy M, Zielonka J, Karoui H, Sikora A, Michalski R, Podsiadły R, Lopez M, Vasquez-Vivar J, Kalyanaraman B, Ouari O) Antioxid Redox Signal 2018 May 20;28(15):1416-1432 PMID: 29037049 PMCID: PMC5910052 10/19/2017    
  • A review of the basics of mitochondrial bioenergetics, metabolism, and related signaling pathways in cancer cells: Therapeutic targeting of tumor mitochondria with lipophilic cationic compounds. (Kalyanaraman B, Cheng G, Hardy M, Ouari O, Lopez M, Joseph J, Zielonka J, Dwinell MB) Redox Biol 2018 04;14:316-327 PMID: 29017115 PMCID: PMC5633086 10/11/2017       18 Citations
  • Recent Developments in the Probes and Assays for Measurement of the Activity of NADPH Oxidases. (Zielonka J, Hardy M, Michalski R, Sikora A, Zielonka M, Cheng G, Ouari O, Podsiadły R, Kalyanaraman B) Cell Biochem Biophys 2017 Dec;75(3-4):335-349 PMID: 28660426 PMCID: PMC5693611 07/01/2017       4 Citations
  • Mitochondria-Targeted Triphenylphosphonium-Based Compounds: Syntheses, Mechanisms of Action, and Therapeutic and Diagnostic Applications. (Zielonka J, Joseph J, Sikora A, Hardy M, Ouari O, Vasquez-Vivar J, Cheng G, Lopez M, Kalyanaraman B) Chem Rev 2017 Aug 09;117(15):10043-10120 PMID: 28654243 PMCID: PMC5611849 06/28/2017       86 Citations
  • European contribution to the study of ROS: A summary of the findings and prospects for the future from the COST action BM1203 (EU-ROS). (Egea J, Fabregat I, Frapart YM, Ghezzi P, Görlach A, Kietzmann T, Kubaichuk K, Knaus UG, Lopez MG, Olaso-Gonzalez G, Petry A, Schulz R, Vina J, Winyard P, Abbas K, Ademowo OS, Afonso CB, Andreadou I, Antelmann H, Antunes F, Aslan M, Bachschmid MM, Barbosa RM, Belousov V, Berndt C, Bernlohr D, Bertrán E, Bindoli A, Bottari SP, Brito PM, Carrara G, Casas AI, Chatzi A, Chondrogianni N, Conrad M, Cooke MS, Costa JG, Cuadrado A, My-Chan Dang P, De Smet B, Debelec-Butuner B, Dias IHK, Dunn JD, Edson AJ, El Assar M, El-Benna J, Ferdinandy P, Fernandes AS, Fladmark KE, Förstermann U, Giniatullin R, Giricz Z, Görbe A, Griffiths H, Hampl V, Hanf A, Herget J, Hernansanz-Agustín P, Hillion M, Huang J, Ilikay S, Jansen-Dürr P, Jaquet V, Joles JA, Kalyanaraman B, Kaminskyy D, Karbaschi M, Kleanthous M, Klotz LO, Korac B, Korkmaz KS, Koziel R, Kračun D, Krause KH, Křen V, Krieg T, Laranjinha J, Lazou A, Li H, Martínez-Ruiz A, Matsui R, McBean GJ, Meredith SP, Messens J, Miguel V, Mikhed Y, Milisav I, Milković L, Miranda-Vizuete A, Mojović M, Monsalve M, Mouthuy PA, Mulvey J, Münzel T, Muzykantov V, Nguyen ITN, Oelze M, Oliveira NG, Palmeira CM, Papaevgeniou N, Pavićević A, Pedre B, Peyrot F, Phylactides M, Pircalabioru GG, Pitt AR, Poulsen HE, Prieto I, Rigobello MP, Robledinos-Antón N, Rodríguez-Mañas L, Rolo AP, Rousset F, Ruskovska T, Saraiva N, Sasson S, Schröder K, Semen K, Seredenina T, Shakirzyanova A, Smith GL, Soldati T, Sousa BC, Spickett CM, Stancic A, Stasia MJ, Steinbrenner H, Stepanić V, Steven S, Tokatlidis K, Tuncay E, Turan B, Ursini F, Vacek J, Vajnerova O, Valentová K, Van Breusegem F, Varisli L, Veal EA, Yalçın AS, Yelisyeyeva O, Žarković N, Zatloukalová M, Zielonka J, Touyz RM, Papapetropoulos A, Grune T, Lamas S, Schmidt HHHW, Di Lisa F, Daiber A) Redox Biol 2017 10;13:94-162 PMID: 28577489 PMCID: PMC5458069 06/04/2017       48 Citations
  • HMGB1-RAGE pathway drives peroxynitrite signaling-induced IBD-like inflammation in murine nonalcoholic fatty liver disease. (Chandrashekaran V, Seth RK, Dattaroy D, Alhasson F, Ziolenka J, Carson J, Berger FG, Kalyanaraman B, Diehl AM, Chatterjee S) Redox Biol 2017 10;13:8-19 PMID: 28551086 PMCID: PMC5447385 05/30/2017       6 Citations
  • Teaching the basics of cancer metabolism: Developing antitumor strategies by exploiting the differences between normal and cancer cell metabolism. (Kalyanaraman B) Redox Biol 2017 08;12:833-842 PMID: 28448945 PMCID: PMC5406543 04/28/2017       30 Citations
  • Modified Metformin as a More Potent Anticancer Drug: Mitochondrial Inhibition, Redox Signaling, Antiproliferative Effects and Future EPR Studies. (Kalyanaraman B, Cheng G, Hardy M, Ouari O, Sikora A, Zielonka J, Dwinell MB) Cell Biochem Biophys 2017 Dec;75(3-4):311-317 PMID: 28429253 PMCID: PMC5680142 04/22/2017       6 Citations
  • Effect of mitochondrially targeted carboxy proxyl nitroxide on Akt-mediated survival in Daudi cells: Significance of a dual mode of action. (Variar G, Pant T, Singh A, Ravichandran A, Swami S, Kalyanaraman B, Dhanasekaran A) PLoS One 2017;12(4):e0174546 PMID: 28426671 PMCID: PMC5398517 04/21/2017    
  • Green fluorescent proteins induce oxidative stress in cells: A worrisome new wrinkle in the application of the GFP reporter system to biological systems? (Kalyanaraman B, Zielonka J) Redox Biol 2017 08;12:755-757 PMID: 28415040 PMCID: PMC5397015 04/18/2017    
  • Mitochondria-targeted metformins: anti-tumour and redox signalling mechanisms. (Kalyanaraman B, Cheng G, Hardy M, Ouari O, Sikora A, Zielonka J, Dwinell M) Interface Focus 2017 Apr 06;7(2):20160109 PMID: 28382202 PMCID: PMC5311906 04/07/2017    
  • Mito-Apocynin Prevents Mitochondrial Dysfunction, Microglial Activation, Oxidative Damage, and Progressive Neurodegeneration in MitoPark Transgenic Mice. (Langley M, Ghosh A, Charli A, Sarkar S, Ay M, Luo J, Zielonka J, Brenza T, Bennett B, Jin H, Ghaisas S, Schlichtmann B, Kim D, Anantharam V, Kanthasamy A, Narasimhan B, Kalyanaraman B, Kanthasamy AG) Antioxid Redox Signal 2017 Nov 10;27(14):1048-1066 PMID: 28375739 PMCID: PMC5651937 04/05/2017       18 Citations
  • Mechanism of Intrinsic Chemiluminescence Production from the Degradation of Persistent Chlorinated Phenols by the Fenton System: A Structure-Activity Relationship Study and the Critical Role of Quinoid and Semiquinone Radical Intermediates. (Gao HY, Mao L, Li F, Xie LN, Huang CH, Shao J, Shao B, Kalyanaraman B, Zhu BZ) Environ Sci Technol 2017 03 07;51(5):2934-2943 PMID: 28128926 PMCID: PMC5806603 01/28/2017       7 Citations
  • Mitochondrial dysfunction activates the AMPK signaling and autophagy to promote cell survival. (Zhao B, Qiang L, Joseph J, Kalyanaraman B, Viollet B, He YY) Genes Dis 2016 Mar;3(1):82-87 PMID: 28066797 PMCID: PMC5215801 01/10/2017    
  • Neuronal protection against oxidative insult by polyanhydride nanoparticle-based mitochondria-targeted antioxidant therapy. (Brenza TM, Ghaisas S, Ramirez JEV, Harischandra D, Anantharam V, Kalyanaraman B, Kanthasamy AG, Narasimhan B) Nanomedicine 2017 04;13(3):809-820 PMID: 27771430 PMCID: PMC5392427 10/25/2016       12 Citations
  • A Critical Review of Methodologies to Detect Reactive Oxygen and Nitrogen Species Stimulated by NADPH Oxidase Enzymes: Implications in Pesticide Toxicity. (Kalyanaraman B, Hardy M, Zielonka J) Curr Pharmacol Rep 2016 Aug;2(4):193-201 PMID: 27774407 PMCID: PMC5070669 10/25/2016    
  • On the use of peroxy-caged luciferin (PCL-1) probe for bioluminescent detection of inflammatory oxidants in vitro and in vivo - Identification of reaction intermediates and oxidant-specific minor products. (Zielonka J, Podsiadły R, Zielonka M, Hardy M, Kalyanaraman B) Free Radic Biol Med 2016 10;99:32-42 PMID: 27458121 PMCID: PMC5107150 10/23/2016       10 Citations
  • Recent developments in detection of superoxide radical anion and hydrogen peroxide: Opportunities, challenges, and implications in redox signaling. (Kalyanaraman B, Hardy M, Podsiadly R, Cheng G, Zielonka J) Arch Biochem Biophys 2017 Mar 01;617:38-47 PMID: 27590268 PMCID: PMC5318280 09/04/2016       24 Citations
  • Mitochondria-Targeted Analogues of Metformin Exhibit Enhanced Antiproliferative and Radiosensitizing Effects in Pancreatic Cancer Cells. (Cheng G, Zielonka J, Ouari O, Lopez M, McAllister D, Boyle K, Barrios CS, Weber JJ, Johnson BD, Hardy M, Dwinell MB, Kalyanaraman B) Cancer Res 2016 07 01;76(13):3904-15 PMID: 27216187 PMCID: PMC4930686 05/25/2016       40 Citations
  • Mechanism of oxidative conversion of Amplex® Red to resorufin: Pulse radiolysis and enzymatic studies. (Dębski D, Smulik R, Zielonka J, Michałowski B, Jakubowska M, Dębowska K, Adamus J, Marcinek A, Kalyanaraman B, Sikora A) Free Radic Biol Med 2016 06;95:323-32 PMID: 27021961 PMCID: PMC5697983 03/30/2016       25 Citations
  • Mitigation of NADPH Oxidase 2 Activity as a Strategy to Inhibit Peroxynitrite Formation. (Zielonka J, Zielonka M, VerPlank L, Cheng G, Hardy M, Ouari O, Ayhan MM, Podsiadły R, Sikora A, Lambeth JD, Kalyanaraman B) J Biol Chem 2016 Mar 25;291(13):7029-44 PMID: 26839313 PMCID: PMC4807286 02/04/2016       28 Citations
  • Mitoapocynin Treatment Protects Against Neuroinflammation and Dopaminergic Neurodegeneration in a Preclinical Animal Model of Parkinson's Disease. (Ghosh A, Langley MR, Harischandra DS, Neal ML, Jin H, Anantharam V, Joseph J, Brenza T, Narasimhan B, Kanthasamy A, Kalyanaraman B, Kanthasamy AG) J Neuroimmune Pharmacol 2016 06;11(2):259-78 PMID: 26838361 PMCID: PMC4995106 02/04/2016       26 Citations
  • The Dose-Response Relationship of bacillus Calmette-Guérin and Urothelial Carcinoma Cell Biology. (Shah G, Zhang G, Chen F, Cao Y, Kalyanaraman B, See WA) J Urol 2016 06;195(6):1903-10 PMID: 26694905 PMCID: PMC5796534 12/24/2015       5 Citations
  • Pancreatic Cancer Cell Migration and Metastasis Is Regulated by Chemokine-Biased Agonism and Bioenergetic Signaling. (Roy I, McAllister DM, Gorse E, Dixon K, Piper CT, Zimmerman NP, Getschman AE, Tsai S, Engle DD, Evans DB, Volkman BF, Kalyanaraman B, Dwinell MB) Cancer Res 2015 Sep 01;75(17):3529-42 PMID: 26330165 PMCID: PMC4560104 09/04/2015       15 Citations
  • Toward selective detection of reactive oxygen and nitrogen species with the use of fluorogenic probes--Limitations, progress, and perspectives. (Debowska K, Debski D, Hardy M, Jakubowska M, Kalyanaraman B, Marcinek A, Michalski R, Michalowski B, Ouari O, Sikora A, Smulik R, Zielonka J) Pharmacol Rep 2015 Aug;67(4):756-64 PMID: 26321278 PMCID: PMC5793900 09/01/2015       24 Citations
  • Intrinsic Chemiluminescence Generation during Advanced Oxidation of Persistent Halogenated Aromatic Carcinogens. (Mao L, Liu YX, Huang CH, Gao HY, Kalyanaraman B, Zhu BZ) Environ Sci Technol 2015 Jul 07;49(13):7940-7 PMID: 26009932 05/27/2015       9 Citations
  • Antiproliferative effects of mitochondria-targeted cationic antioxidants and analogs: Role of mitochondrial bioenergetics and energy-sensing mechanism. (Cheng G, Zielonka J, McAllister D, Hardy M, Ouari O, Joseph J, Dwinell MB, Kalyanaraman B) Cancer Lett 2015 Aug 28;365(1):96-106 PMID: 26004344 PMCID: PMC4476640 05/26/2015       22 Citations
  • NADPH Oxidase-Derived Peroxynitrite Drives Inflammation in Mice and Human Nonalcoholic Steatohepatitis via TLR4-Lipid Raft Recruitment. (Das S, Alhasson F, Dattaroy D, Pourhoseini S, Seth RK, Nagarkatti M, Nagarkatti PS, Michelotti GA, Diehl AM, Kalyanaraman B, Chatterjee S) Am J Pathol 2015 Jul;185(7):1944-57 PMID: 25989356 PMCID: PMC4483465 05/20/2015       15 Citations
  • Enhanced antitumor activity of 3-bromopyruvate in combination with rapamycin in vivo and in vitro. (Zhang Q, Pan J, Lubet RA, Komas SM, Kalyanaraman B, Wang Y, You M) Cancer Prev Res (Phila) 2015 Apr;8(4):318-26 PMID: 25644152 PMCID: PMC6004825 02/04/2015       5 Citations
  • Detection and differentiation between peroxynitrite and hydroperoxides using mitochondria-targeted arylboronic acid. (Zielonka J, Sikora A, Adamus J, Kalyanaraman B) Methods Mol Biol 2015;1264:171-81 PMID: 25631013 PMCID: PMC4451192 01/30/2015       12 Citations
  • Even free radicals should follow some rules: a guide to free radical research terminology and methodology. (Forman HJ, Augusto O, Brigelius-Flohe R, Dennery PA, Kalyanaraman B, Ischiropoulos H, Mann GE, Radi R, Roberts LJ 2nd, Vina J, Davies KJ) Free Radic Biol Med 2015 Jan;78:233-5 PMID: 25462642 12/03/2014       109 Citations
  • Nitroxyl (HNO) reacts with molecular oxygen and forms peroxynitrite at physiological pH. Biological Implications. (Smulik R, Dębski D, Zielonka J, Michałowski B, Adamus J, Marcinek A, Kalyanaraman B, Sikora A) J Biol Chem 2014 Dec 19;289(51):35570-81 PMID: 25378389 PMCID: PMC4271240 11/08/2014       32 Citations
  • A novel mitochondrially-targeted apocynin derivative prevents hyposmia and loss of motor function in the leucine-rich repeat kinase 2 (LRRK2(R1441G)) transgenic mouse model of Parkinson's disease. (Dranka BP, Gifford A, McAllister D, Zielonka J, Joseph J, O'Hara CL, Stucky CL, Kanthasamy AG, Kalyanaraman B) Neurosci Lett 2014 Nov 07;583:159-64 PMID: 25263790 PMCID: PMC4253647 09/30/2014       17 Citations
  • Honokiol inhibits lung tumorigenesis through inhibition of mitochondrial function. (Pan J, Zhang Q, Liu Q, Komas SM, Kalyanaraman B, Lubet RA, Wang Y, You M) Cancer Prev Res (Phila) 2014 Nov;7(11):1149-59 PMID: 25245764 PMCID: PMC6010030 09/24/2014       14 Citations
  • Real-time measurements of amino acid and protein hydroperoxides using coumarin boronic acid. (Michalski R, Zielonka J, Gapys E, Marcinek A, Joseph J, Kalyanaraman B) J Biol Chem 2014 Aug 08;289(32):22536-53 PMID: 24928516 PMCID: PMC4139259 06/15/2014       30 Citations
  • H2O2 generation by bacillus Calmette-Guérin induces the cellular oxidative stress response required for bacillus Calmette-Guérin direct effects on urothelial carcinoma biology. (Shah G, Zielonka J, Chen F, Zhang G, Cao Y, Kalyanaraman B, See W) J Urol 2014 Oct;192(4):1238-48 PMID: 24928267 PMCID: PMC5798233 06/15/2014       7 Citations
  • Mitochondria-targeted spin traps: synthesis, superoxide spin trapping, and mitochondrial uptake. (Hardy M, Poulhés F, Rizzato E, Rockenbauer A, Banaszak K, Karoui H, Lopez M, Zielonka J, Vasquez-Vivar J, Sethumadhavan S, Kalyanaraman B, Tordo P, Ouari O) Chem Res Toxicol 2014 Jul 21;27(7):1155-65 PMID: 24890552 PMCID: PMC5452977 06/04/2014       13 Citations
  • Profiling and targeting of cellular bioenergetics: inhibition of pancreatic cancer cell proliferation. (Cheng G, Zielonka J, McAllister D, Tsai S, Dwinell MB, Kalyanaraman B) Br J Cancer 2014 Jul 08;111(1):85-93 PMID: 24867695 PMCID: PMC4090735 05/29/2014       35 Citations
  • High-throughput assays for superoxide and hydrogen peroxide: design of a screening workflow to identify inhibitors of NADPH oxidases. (Zielonka J, Cheng G, Zielonka M, Ganesh T, Sun A, Joseph J, Michalski R, O'Brien WJ, Lambeth JD, Kalyanaraman B) J Biol Chem 2014 Jun 06;289(23):16176-89 PMID: 24764302 PMCID: PMC4047388 04/26/2014       26 Citations
  • Inducible nitric oxide synthase is key to peroxynitrite-mediated, LPS-induced protein radical formation in murine microglial BV2 cells. (Kumar A, Chen SH, Kadiiska MB, Hong JS, Zielonka J, Kalyanaraman B, Mason RP) Free Radic Biol Med 2014 Aug;73:51-9 PMID: 24746617 PMCID: PMC4111989 04/22/2014       40 Citations
  • Docosahexaenoic acid attenuates breast cancer cell metabolism and the Warburg phenotype by targeting bioenergetic function. (Mouradian M, Kikawa KD, Dranka BP, Komas SM, Kalyanaraman B, Pardini RS) Mol Carcinog 2015 Sep;54(9):810-20 PMID: 24729481 04/15/2014       17 Citations
  • Detection and identification of oxidants formed during •NO/O2•⁻ reaction: a multi-well plate CW-EPR spectroscopy combined with HPLC analyses. (Koto T, Michalski R, Zielonka J, Joseph J, Kalyanaraman B) Free Radic Res 2014 Apr;48(4):478-86 PMID: 24460755 PMCID: PMC4780754 01/28/2014       4 Citations
  • On the use of fluorescence lifetime imaging and dihydroethidium to detect superoxide in intact animals and ex vivo tissues: a reassessment. (Michalski R, Michalowski B, Sikora A, Zielonka J, Kalyanaraman B) Free Radic Biol Med 2014 Feb;67:278-84 PMID: 24200598 PMCID: PMC4275029 11/10/2013       26 Citations
  • Oxidative stress induced mitochondrial protein kinase A mediates cytochrome c oxidase dysfunction. (Srinivasan S, Spear J, Chandran K, Joseph J, Kalyanaraman B, Avadhani NG) PLoS One 2013;8(10):e77129 PMID: 24130844 PMCID: PMC3795003 10/17/2013       25 Citations
  • On the use of L-012, a luminol-based chemiluminescent probe, for detecting superoxide and identifying inhibitors of NADPH oxidase: a reevaluation. (Zielonka J, Lambeth JD, Kalyanaraman B) Free Radic Biol Med 2013 Dec;65:1310-1314 PMID: 24080119 PMCID: PMC4274999 10/02/2013       41 Citations
  • Mitochondria-targeted antioxidants for treatment of Parkinson's disease: preclinical and clinical outcomes. (Jin H, Kanthasamy A, Ghosh A, Anantharam V, Kalyanaraman B, Kanthasamy AG) Biochim Biophys Acta 2014 Aug;1842(8):1282-94 PMID: 24060637 PMCID: PMC3961561 09/26/2013       119 Citations
  • iNOS expression and NO production contribute to the direct effects of BCG on urothelial carcinoma cell biology. (Shah G, Zhang G, Chen F, Cao Y, Kalyanaraman B, See WA) Urol Oncol 2014 Jan;32(1):45.e1-9 PMID: 24054867 PMCID: PMC5798243 09/24/2013       7 Citations
  • Loss of bacillus Calmette-Guérin viability adversely affects the direct response of urothelial carcinoma cells to bacillus Calmette-Guérin exposure. (Shah G, Zhang G, Chen F, Cao Y, Kalyanaraman B, See W) J Urol 2014 Mar;191(3):823-9 PMID: 24035882 PMCID: PMC5798236 09/17/2013       3 Citations
  • Teaching the basics of redox biology to medical and graduate students: Oxidants, antioxidants and disease mechanisms. (Kalyanaraman B) Redox Biol 2013 Feb 08;1:244-57 PMID: 24024158 PMCID: PMC3757692 09/12/2013       199 Citations
  • Mito-tempol and dexrazoxane exhibit cardioprotective and chemotherapeutic effects through specific protein oxidation and autophagy in a syngeneic breast tumor preclinical model. (Dickey JS, Gonzalez Y, Aryal B, Mog S, Nakamura AJ, Redon CE, Baxa U, Rosen E, Cheng G, Zielonka J, Parekh P, Mason KP, Joseph J, Kalyanaraman B, Bonner W, Herman E, Shacter E, Rao VA) PLoS One 2013;8(8):e70575 PMID: 23940596 PMCID: PMC3734284 08/14/2013       34 Citations
  • Mitochondria-targeted antioxidant and glycolysis inhibition: synergistic therapy in hepatocellular carcinoma. (Dilip A, Cheng G, Joseph J, Kunnimalaiyaan S, Kalyanaraman B, Kunnimalaiyaan M, Gamblin TC) Anticancer Drugs 2013 Oct;24(9):881-8 PMID: 23872912 PMCID: PMC4028966 07/23/2013       14 Citations
  • Real-time monitoring of reactive oxygen and nitrogen species in a multiwell plate using the diagnostic marker products of specific probes. (Zielonka J, Joseph J, Sikora A, Kalyanaraman B) Methods Enzymol 2013;526:145-57 PMID: 23791099 06/26/2013       14 Citations
  • Mitochondria-targeted vitamin E analogs inhibit breast cancer cell energy metabolism and promote cell death. (Cheng G, Zielonka J, McAllister DM, Mackinnon AC Jr, Joseph J, Dwinell MB, Kalyanaraman B) BMC Cancer 2013 Jun 13;13:285 PMID: 23764021 PMCID: PMC3686663 06/15/2013       50 Citations
  • The first purification and unequivocal characterization of the radical form of the carbon-centered quinone ketoxy radical adduct. (Huang CH, Shan GQ, Mao L, Kalyanaraman B, Qin H, Ren FR, Zhu BZ) Chem Commun (Camb) 2013 Jul 21;49(57):6436-8 PMID: 23752136 06/12/2013       10 Citations
  • Diapocynin prevents early Parkinson's disease symptoms in the leucine-rich repeat kinase 2 (LRRK2R¹⁴⁴¹G) transgenic mouse. (Dranka BP, Gifford A, Ghosh A, Zielonka J, Joseph J, Kanthasamy AG, Kalyanaraman B) Neurosci Lett 2013 Aug 09;549:57-62 PMID: 23721786 PMCID: PMC3729885 06/01/2013       21 Citations
  • An adenosine-mediated signaling pathway suppresses prenylation of the GTPase Rap1B and promotes cell scattering. (Ntantie E, Gonyo P, Lorimer EL, Hauser AD, Schuld N, McAllister D, Kalyanaraman B, Dwinell MB, Auchampach JA, Williams CL) Sci Signal 2013 May 28;6(277):ra39 PMID: 23716716 PMCID: PMC4278376 05/30/2013       46 Citations
  • Molecular mechanism of metal-independent decomposition of lipid hydroperoxide 13-HPODE by halogenated quinoid carcinogens. (Qin H, Huang CH, Mao L, Xia HY, Kalyanaraman B, Shao J, Shan GQ, Zhu BZ) Free Radic Biol Med 2013 Oct;63:459-66 PMID: 23680403 PMCID: PMC5806606 05/18/2013    
  • HPLC-based monitoring of products formed from hydroethidine-based fluorogenic probes--the ultimate approach for intra- and extracellular superoxide detection. (Kalyanaraman B, Dranka BP, Hardy M, Michalski R, Zielonka J) Biochim Biophys Acta 2014 Feb;1840(2):739-44 PMID: 23668959 PMCID: PMC3858408 05/15/2013       55 Citations
  • Reaction between peroxynitrite and triphenylphosphonium-substituted arylboronic acid isomers: identification of diagnostic marker products and biological implications. (Sikora A, Zielonka J, Adamus J, Debski D, Dybala-Defratyka A, Michalowski B, Joseph J, Hartley RC, Murphy MP, Kalyanaraman B) Chem Res Toxicol 2013 Jun 17;26(6):856-67 PMID: 23611338 PMCID: PMC3700382 04/25/2013       27 Citations
  • Redox activation of Fe(III)-thiosemicarbazones and Fe(III)-bleomycin by thioredoxin reductase: specificity of enzymatic redox centers and analysis of reactive species formation by ESR spin trapping. (Myers JM, Cheng Q, Antholine WE, Kalyanaraman B, Filipovska A, Arnér ES, Myers CR) Free Radic Biol Med 2013 Jul;60:183-94 PMID: 23485585 PMCID: PMC3654041 03/15/2013       10 Citations
  • Potent methyl oxidation of 5-methyl-2'-deoxycytidine by halogenated quinoid carcinogens and hydrogen peroxide via a metal-independent mechanism. (Shao J, Huang CH, Kalyanaraman B, Zhu BZ) Free Radic Biol Med 2013 Jul;60:177-82 PMID: 23376470 PMCID: PMC4476646 02/05/2013       15 Citations
  • Peroxynitrite formation in nitric oxide-exposed submitochondrial particles: detection, oxidative damage and catalytic removal by Mn-porphyrins. (Valez V, Cassina A, Batinic-Haberle I, Kalyanaraman B, Ferrer-Sueta G, Radi R) Arch Biochem Biophys 2013 Jan 01;529(1):45-54 PMID: 23142682 PMCID: PMC3534903 11/13/2012       25 Citations
  • Anti-inflammatory and neuroprotective effects of an orally active apocynin derivative in pre-clinical models of Parkinson's disease. (Ghosh A, Kanthasamy A, Joseph J, Anantharam V, Srivastava P, Dranka BP, Kalyanaraman B, Kanthasamy AG) J Neuroinflammation 2012 Oct 23;9:241 PMID: 23092448 PMCID: PMC3488558 10/25/2012       56 Citations
  • Hydropropidine: a novel, cell-impermeant fluorogenic probe for detecting extracellular superoxide. (Michalski R, Zielonka J, Hardy M, Joseph J, Kalyanaraman B) Free Radic Biol Med 2013 Jan;54:135-47 PMID: 23051008 PMCID: PMC3711142 10/12/2012       26 Citations
  • Mitochondrial-targeted nitroxides disrupt mitochondrial architecture and inhibit expression of peroxiredoxin 3 and FOXM1 in malignant mesothelioma cells. (Cunniff B, Benson K, Stumpff J, Newick K, Held P, Taatjes D, Joseph J, Kalyanaraman B, Heintz NH) J Cell Physiol 2013 Apr;228(4):835-45 PMID: 23018647 PMCID: PMC3928986 09/29/2012       25 Citations
  • Unprecedented hydroxyl radical-dependent two-step chemiluminescence production by polyhalogenated quinoid carcinogens and H2O2. (Zhu BZ, Mao L, Huang CH, Qin H, Fan RM, Kalyanaraman B, Zhu JG) Proc Natl Acad Sci U S A 2012 Oct 02;109(40):16046-51 PMID: 22988069 PMCID: PMC3479549 09/19/2012       41 Citations
  • Boronate probes as diagnostic tools for real time monitoring of peroxynitrite and hydroperoxides. (Zielonka J, Sikora A, Hardy M, Joseph J, Dranka BP, Kalyanaraman B) Chem Res Toxicol 2012 Sep 17;25(9):1793-9 PMID: 22731669 PMCID: PMC3501381 06/27/2012       100 Citations
  • Alterations in bioenergetic function induced by Parkinson's disease mimetic compounds: lack of correlation with superoxide generation. (Dranka BP, Zielonka J, Kanthasamy AG, Kalyanaraman B) J Neurochem 2012 Sep;122(5):941-51 PMID: 22708893 PMCID: PMC3423581 06/20/2012       37 Citations
  • Mitochondrial reactive oxygen species generation triggers inflammatory response and tissue injury associated with hepatic ischemia-reperfusion: therapeutic potential of mitochondrially targeted antioxidants. (Mukhopadhyay P, Horváth B, Zsengellėr Z, Bátkai S, Cao Z, Kechrid M, Holovac E, Erdėlyi K, Tanchian G, Liaudet L, Stillman IE, Joseph J, Kalyanaraman B, Pacher P) Free Radic Biol Med 2012 Sep 01;53(5):1123-38 PMID: 22683818 PMCID: PMC3432152 06/12/2012       69 Citations
  • Molecular basis of intramolecular electron transfer in proteins during radical-mediated oxidations: computer simulation studies in model tyrosine-cysteine peptides in solution. (Petruk AA, Bartesaghi S, Trujillo M, Estrin DA, Murgida D, Kalyanaraman B, Marti MA, Radi R) Arch Biochem Biophys 2012 Sep 01;525(1):82-91 PMID: 22640642 PMCID: PMC3414218 05/30/2012       23 Citations
  • Cisplatin nephrotoxicity involves mitochondrial injury with impaired tubular mitochondrial enzyme activity. (Zsengellér ZK, Ellezian L, Brown D, Horváth B, Mukhopadhyay P, Kalyanaraman B, Parikh SM, Karumanchi SA, Stillman IE, Pacher P) J Histochem Cytochem 2012 Jul;60(7):521-9 PMID: 22511597 PMCID: PMC3460350 04/19/2012       50 Citations
  • Mitochondria-targeted drugs synergize with 2-deoxyglucose to trigger breast cancer cell death. (Cheng G, Zielonka J, Dranka BP, McAllister D, Mackinnon AC Jr, Joseph J, Kalyanaraman B) Cancer Res 2012 May 15;72(10):2634-44 PMID: 22431711 PMCID: PMC3700358 03/21/2012       111 Citations
  • Additive effects of mitochondrion-targeted cytochrome CYP2E1 and alcohol toxicity on cytochrome c oxidase function and stability of respirosome complexes. (Bansal S, Srinivasan S, Anandasadagopan S, Chowdhury AR, Selvaraj V, Kalyanaraman B, Joseph J, Avadhani NG) J Biol Chem 2012 May 04;287(19):15284-97 PMID: 22396533 PMCID: PMC3346148 03/08/2012       16 Citations
  • Particulate matter Air Pollution induces hypermethylation of the p16 promoter Via a mitochondrial ROS-JNK-DNMT1 pathway. (Soberanes S, Gonzalez A, Urich D, Chiarella SE, Radigan KA, Osornio-Vargas A, Joseph J, Kalyanaraman B, Ridge KM, Chandel NS, Mutlu GM, De Vizcaya-Ruiz A, Budinger GR) Sci Rep 2012;2:275 PMID: 22355787 PMCID: PMC3281276 02/23/2012    
  • Global profiling of reactive oxygen and nitrogen species in biological systems: high-throughput real-time analyses. (Zielonka J, Zielonka M, Sikora A, Adamus J, Joseph J, Hardy M, Ouari O, Dranka BP, Kalyanaraman B) J Biol Chem 2012 Jan 27;287(5):2984-95 PMID: 22139901 PMCID: PMC3270955 12/06/2011       95 Citations
  • Mitochondrial-targeted antioxidants represent a promising approach for prevention of cisplatin-induced nephropathy. (Mukhopadhyay P, Horváth B, Zsengellér Z, Zielonka J, Tanchian G, Holovac E, Kechrid M, Patel V, Stillman IE, Parikh SM, Joseph J, Kalyanaraman B, Pacher P) Free Radic Biol Med 2012 Jan 15;52(2):497-506 PMID: 22120494 PMCID: PMC3253235 11/29/2011       108 Citations
  • Measuring reactive oxygen and nitrogen species with fluorescent probes: challenges and limitations. (Kalyanaraman B, Darley-Usmar V, Davies KJ, Dennery PA, Forman HJ, Grisham MB, Mann GE, Moore K, Roberts LJ 2nd, Ischiropoulos H) Free Radic Biol Med 2012 Jan 01;52(1):1-6 PMID: 22027063 PMCID: PMC3911769 10/27/2011       721 Citations
  • Mitochondrial complex III ROS regulate adipocyte differentiation. (Tormos KV, Anso E, Hamanaka RB, Eisenbart J, Joseph J, Kalyanaraman B, Chandel NS) Cell Metab 2011 Oct 05;14(4):537-44 PMID: 21982713 PMCID: PMC3190168 10/11/2011       289 Citations
  • Oxidative chemistry of fluorescent dyes: implications in the detection of reactive oxygen and nitrogen species. (Kalyanaraman B) Biochem Soc Trans 2011 Oct;39(5):1221-5 PMID: 21936793 09/23/2011       47 Citations
  • Diapocynin and apocynin administration fails to significantly extend survival in G93A SOD1 ALS mice. (Trumbull KA, McAllister D, Gandelman MM, Fung WY, Lew T, Brennan L, Lopez N, Morré J, Kalyanaraman B, Beckman JS) Neurobiol Dis 2012 Jan;45(1):137-44 PMID: 21820513 PMCID: PMC3710723 08/09/2011       29 Citations
  • Mitochondria-targeted nitroxides exacerbate fluvastatin-mediated cytostatic and cytotoxic effects in breast cancer cells. (Cheng G, Lopez M, Zielonka J, Hauser AD, Joseph J, McAllister D, Rowe JJ, Sugg SL, Williams CL, Kalyanaraman B) Cancer Biol Ther 2011 Oct 15;12(8):707-17 PMID: 21799303 PMCID: PMC3218525 07/30/2011       19 Citations
  • Mitochondria-targeted ubiquinone (MitoQ) decreases ethanol-dependent micro and macro hepatosteatosis. (Chacko BK, Srivastava A, Johnson MS, Benavides GA, Chang MJ, Ye Y, Jhala N, Murphy MP, Kalyanaraman B, Darley-Usmar VM) Hepatology 2011 Jul;54(1):153-63 PMID: 21520201 PMCID: PMC3125473 04/27/2011       69 Citations
  • Unraveling the biological roles of reactive oxygen species. (Murphy MP, Holmgren A, Larsson NG, Halliwell B, Chang CJ, Kalyanaraman B, Rhee SG, Thornalley PJ, Partridge L, Gems D, Nyström T, Belousov V, Schumacker PT, Winterbourn CC) Cell Metab 2011 Apr 06;13(4):361-366 PMID: 21459321 PMCID: PMC4445605 04/05/2011       362 Citations
  • Reaction between peroxynitrite and boronates: EPR spin-trapping, HPLC Analyses, and quantum mechanical study of the free radical pathway. (Sikora A, Zielonka J, Lopez M, Dybala-Defratyka A, Joseph J, Marcinek A, Kalyanaraman B) Chem Res Toxicol 2011 May 16;24(5):687-97 PMID: 21434648 PMCID: PMC3743543 03/26/2011    
  • Analysis of proteome changes in doxorubicin-treated adult rat cardiomyocyte. (Kumar SN, Konorev EA, Aggarwal D, Kalyanaraman B) J Proteomics 2011 May 01;74(5):683-97 PMID: 21338723 PMCID: PMC3298037 02/23/2011       18 Citations
  • Tyrosine-lipid peroxide adducts from radical termination: para coupling and intramolecular Diels-Alder cyclization. (Shchepin R, Möller MN, Kim HY, Hatch DM, Bartesaghi S, Kalyanaraman B, Radi R, Porter NA) J Am Chem Soc 2010 Dec 15;132(49):17490-500 PMID: 21090613 PMCID: PMC3677824 11/26/2010       20 Citations
  • Detoxifying carcinogenic polyhalogenated quinones by hydroxamic acids via an unusual double Lossen rearrangement mechanism. (Zhu BZ, Zhu JG, Mao L, Kalyanaraman B, Shan GQ) Proc Natl Acad Sci U S A 2010 Nov 30;107(48):20686-90 PMID: 21076034 PMCID: PMC2996439 11/16/2010       28 Citations
  • Ergothioneine prevents copper-induced oxidative damage to DNA and protein by forming a redox-inactive ergothioneine-copper complex. (Zhu BZ, Mao L, Fan RM, Zhu JG, Zhang YN, Wang J, Kalyanaraman B, Frei B) Chem Res Toxicol 2011 Jan 14;24(1):30-4 PMID: 21047085 11/05/2010       39 Citations
  • Oxidation of histidine residues in copper-zinc superoxide dismutase by bicarbonate-stimulated peroxidase and thiol oxidase activities: pulse EPR and NMR studies. (Chandran K, McCracken J, Peterson FC, Antholine WE, Volkman BF, Kalyanaraman B) Biochemistry 2010 Dec 21;49(50):10616-22 PMID: 21038859 PMCID: PMC3501376 11/03/2010       11 Citations
  • Neuroprotection by a mitochondria-targeted drug in a Parkinson's disease model. (Ghosh A, Chandran K, Kalivendi SV, Joseph J, Antholine WE, Hillard CJ, Kanthasamy A, Kanthasamy A, Kalyanaraman B) Free Radic Biol Med 2010 Dec 01;49(11):1674-84 PMID: 20828611 PMCID: PMC4020411 09/11/2010       88 Citations
  • Prevention of diabetic nephropathy in Ins2(+/)⁻(AkitaJ) mice by the mitochondria-targeted therapy MitoQ. (Chacko BK, Reily C, Srivastava A, Johnson MS, Ye Y, Ulasova E, Agarwal A, Zinn KR, Murphy MP, Kalyanaraman B, Darley-Usmar V) Biochem J 2010 Nov 15;432(1):9-19 PMID: 20825366 PMCID: PMC2973231 09/10/2010       135 Citations
  • The antioxidant transcription factor Nrf2 negatively regulates autophagy and growth arrest induced by the anticancer redox agent mitoquinone. (Rao VA, Klein SR, Bonar SJ, Zielonka J, Mizuno N, Dickey JS, Keller PW, Joseph J, Kalyanaraman B, Shacter E) J Biol Chem 2010 Nov 05;285(45):34447-59 PMID: 20805228 PMCID: PMC2966059 09/02/2010       77 Citations
  • Reactive oxygen species control senescence-associated matrix metalloproteinase-1 through c-Jun-N-terminal kinase. (Dasgupta J, Kar S, Liu R, Joseph J, Kalyanaraman B, Remington SJ, Chen C, Melendez JA) J Cell Physiol 2010 Oct;225(1):52-62 PMID: 20648623 PMCID: PMC2913426 07/22/2010       37 Citations
  • NADPH oxidase 2 mediates intermittent hypoxia-induced mitochondrial complex I inhibition: relevance to blood pressure changes in rats. (Khan SA, Nanduri J, Yuan G, Kinsman B, Kumar GK, Joseph J, Kalyanaraman B, Prabhakar NR) Antioxid Redox Signal 2011 Feb 15;14(4):533-42 PMID: 20618070 PMCID: PMC3038125 07/14/2010       50 Citations
  • The selenium-independent inherent pro-oxidant NADPH oxidase activity of mammalian thioredoxin reductase and its selenium-dependent direct peroxidase activities. (Cheng Q, Antholine WE, Myers JM, Kalyanaraman B, Arnér ES, Myers CR) J Biol Chem 2010 Jul 09;285(28):21708-23 PMID: 20457604 PMCID: PMC2898413 05/12/2010       33 Citations
  • Mitochondrial metabolism and ROS generation are essential for Kras-mediated tumorigenicity. (Weinberg F, Hamanaka R, Wheaton WW, Weinberg S, Joseph J, Lopez M, Kalyanaraman B, Mutlu GM, Budinger GR, Chandel NS) Proc Natl Acad Sci U S A 2010 May 11;107(19):8788-93 PMID: 20421486 PMCID: PMC2889315 04/28/2010       683 Citations
  • Role of mitochondrial reactive oxygen species in osteoclast differentiation. (Srinivasan S, Koenigstein A, Joseph J, Sun L, Kalyanaraman B, Zaidi M, Avadhani NG) Ann N Y Acad Sci 2010 Mar;1192:245-52 PMID: 20392243 PMCID: PMC2856121 04/16/2010    
  • Peroxynitrite is the major species formed from different flux ratios of co-generated nitric oxide and superoxide: direct reaction with boronate-based fluorescent probe. (Zielonka J, Sikora A, Joseph J, Kalyanaraman B) J Biol Chem 2010 May 07;285(19):14210-6 PMID: 20194496 PMCID: PMC2863194 03/03/2010       118 Citations
  • Lipid peroxyl radicals mediate tyrosine dimerization and nitration in membranes. (Bartesaghi S, Wenzel J, Trujillo M, López M, Joseph J, Kalyanaraman B, Radi R) Chem Res Toxicol 2010 Apr 19;23(4):821-35 PMID: 20170094 PMCID: PMC3506709 02/23/2010       50 Citations
  • Hydroethidine- and MitoSOX-derived red fluorescence is not a reliable indicator of intracellular superoxide formation: another inconvenient truth. (Zielonka J, Kalyanaraman B) Free Radic Biol Med 2010 Apr 15;48(8):983-1001 PMID: 20116425 PMCID: PMC3587154 02/02/2010       263 Citations
  • Mitochondrial targeting of the electrophilic lipid 15-deoxy-Delta12,14-prostaglandin J2 increases apoptotic efficacy via redox cell signalling mechanisms. (Diers AR, Higdon AN, Ricart KC, Johnson MS, Agarwal A, Kalyanaraman B, Landar A, Darley-Usmar VM) Biochem J 2010 Jan 27;426(1):31-41 PMID: 19916962 PMCID: PMC3079364 11/18/2009       43 Citations
  • A (99m)Tc-labeled triphenylphosphonium derivative for the early detection of breast tumors. (Li Z, Lopez M, Hardy M, McAllister DM, Kalyanaraman B, Zhao M) Cancer Biother Radiopharm 2009 Oct;24(5):579-87 PMID: 19877888 PMCID: PMC2883499 11/03/2009       15 Citations
  • Physiological fluctuation of (99m)Tc-sestamibi uptake in normal mammary glands: a systematic investigation in female rats. (Larson M, Larson M, Li Z, Larson M, Li Z, Hall CL, Jensen E, McAllister DM, Kalyanaraman B, Zhao M) Acta Radiol 2009 Nov;50(9):975-8 PMID: 19863405 10/30/2009       3 Citations
  • Oxidants induce alternative splicing of alpha-synuclein: Implications for Parkinson's disease. (Kalivendi SV, Yedlapudi D, Hillard CJ, Kalyanaraman B) Free Radic Biol Med 2010 Feb 01;48(3):377-83 PMID: 19857570 PMCID: PMC4485429 10/28/2009       30 Citations
  • Mitochondrially targeted antioxidants for the treatment of cardiovascular diseases. (Subramanian S, Kalyanaraman B, Migrino RQ) Recent Pat Cardiovasc Drug Discov 2010 Jan;5(1):54-65 PMID: 19807685 10/08/2009       35 Citations
  • Direct oxidation of boronates by peroxynitrite: mechanism and implications in fluorescence imaging of peroxynitrite. (Sikora A, Zielonka J, Lopez M, Joseph J, Kalyanaraman B) Free Radic Biol Med 2009 Nov 15;47(10):1401-7 PMID: 19686842 PMCID: PMC3375817 08/19/2009       158 Citations
  • Decreased S-nitrosation of peptide thiols in the membrane interior. (Zhang H, Andrekopoulos C, Xu Y, Joseph J, Hogg N, Feix J, Kalyanaraman B) Free Radic Biol Med 2009 Oct 01;47(7):962-8 PMID: 19573593 PMCID: PMC2874255 07/04/2009       12 Citations
  • Metal-independent decomposition of hydroperoxides by halogenated quinones: detection and identification of a quinone ketoxy radical. (Zhu BZ, Shan GQ, Huang CH, Kalyanaraman B, Mao L, Du YG) Proc Natl Acad Sci U S A 2009 Jul 14;106(28):11466-71 PMID: 19556549 PMCID: PMC2710671 06/27/2009       44 Citations
  • Role of nuclear-encoded subunit Vb in the assembly and stability of cytochrome c oxidase complex: implications in mitochondrial dysfunction and ROS production. (Galati D, Srinivasan S, Raza H, Prabu SK, Hardy M, Chandran K, Lopez M, Kalyanaraman B, Avadhani NG) Biochem J 2009 May 27;420(3):439-49 PMID: 19338496 PMCID: PMC2735414 04/03/2009       55 Citations
  • Doxorubicin inactivates myocardial cytochrome c oxidase in rats: cardioprotection by Mito-Q. (Chandran K, Aggarwal D, Migrino RQ, Joseph J, McAllister D, Konorev EA, Antholine WE, Zielonka J, Srinivasan S, Avadhani NG, Kalyanaraman B) Biophys J 2009 Feb 18;96(4):1388-98 PMID: 19217856 PMCID: PMC2717244 02/17/2009       111 Citations
  • The effect of neighboring methionine residue on tyrosine nitration and oxidation in peptides treated with MPO, H2O2, and NO2(-) or peroxynitrite and bicarbonate: role of intramolecular electron transfer mechanism? (Zhang H, Zielonka J, Sikora A, Joseph J, Xu Y, Kalyanaraman B) Arch Biochem Biophys 2009 Apr 15;484(2):134-45 PMID: 19056332 PMCID: PMC2874256 12/06/2008       17 Citations
  • HPLC study of oxidation products of hydroethidine in chemical and biological systems: ramifications in superoxide measurements. (Zielonka J, Hardy M, Kalyanaraman B) Free Radic Biol Med 2009 Feb 01;46(3):329-38 PMID: 19026738 PMCID: PMC3375818 11/26/2008       96 Citations
  • Differences in doxorubicin-induced apoptotic signaling in adult and immature cardiomyocytes. (Konorev EA, Vanamala S, Kalyanaraman B) Free Radic Biol Med 2008 Dec 15;45(12):1723-8 PMID: 18926904 PMCID: PMC3039518 10/18/2008       50 Citations
  • "ROS-generating mitochondrial DNA mutations can regulate tumor cell metastasis"--a critical commentary. (Zielonka J, Kalyanaraman B) Free Radic Biol Med 2008 Nov 01;45(9):1217-9 PMID: 18789385 PMCID: PMC3595710 09/16/2008       28 Citations
  • Cytokines and lipopolysaccharides induce inducible nitric oxide synthase but not enzyme activity in adult rat cardiomyocytes. (Vásquez-Vivar J, Whitsett J, Ionova I, Konorev E, Zielonka J, Kalyanaraman B, Shi Y, Pieper GM) Free Radic Biol Med 2008 Oct 01;45(7):994-1001 PMID: 18634867 PMCID: PMC2578873 07/19/2008       13 Citations
  • Tyrosine nitration, dimerization, and hydroxylation by peroxynitrite in membranes as studied by the hydrophobic probe N-t-BOC-l-tyrosine tert-butyl ester. (Bartesaghi S, Peluffo G, Zhang H, Joseph J, Kalyanaraman B, Radi R) Methods Enzymol 2008;441:217-36 PMID: 18554537 06/17/2008       10 Citations
  • Redox-based regulation of signal transduction: principles, pitfalls, and promises. (Janssen-Heininger YM, Mossman BT, Heintz NH, Forman HJ, Kalyanaraman B, Finkel T, Stamler JS, Rhee SG, van der Vliet A) Free Radic Biol Med 2008 Jul 01;45(1):1-17 PMID: 18423411 PMCID: PMC2453533 04/22/2008       470 Citations
  • Influence of intramolecular electron transfer mechanism in biological nitration, nitrosation, and oxidation of redox-sensitive amino acids. (Zhang H, Xu Y, Joseph J, Kalyanaraman B) Methods Enzymol 2008;440:65-94 PMID: 18423211 04/22/2008       10 Citations
  • L-Xylulose reductase is involved in 9,10-phenanthrenequinone-induced apoptosis in human T lymphoma cells. (Matsunaga T, Kamiya T, Sumi D, Kumagai Y, Kalyanaraman B, Hara A) Free Radic Biol Med 2008 Mar 15;44(6):1191-202 PMID: 18206670 01/22/2008       44 Citations
  • Detection of 2-hydroxyethidium in cellular systems: a unique marker product of superoxide and hydroethidine. (Zielonka J, Vasquez-Vivar J, Kalyanaraman B) Nat Protoc 2008;3(1):8-21 PMID: 18193017 01/15/2008       219 Citations
  • Cytochrome c-mediated oxidation of hydroethidine and mito-hydroethidine in mitochondria: identification of homo- and heterodimers. (Zielonka J, Srinivasan S, Hardy M, Ouari O, Lopez M, Vasquez-Vivar J, Avadhani NG, Kalyanaraman B) Free Radic Biol Med 2008 Mar 01;44(5):835-46 PMID: 18155177 PMCID: PMC2692199 12/25/2007       62 Citations
  • Molecular mechanism for metal-independent production of hydroxyl radicals by hydrogen peroxide and halogenated quinones. (Zhu BZ, Kalyanaraman B, Jiang GB) Proc Natl Acad Sci U S A 2007 Nov 06;104(45):17575-8 PMID: 17968010 PMCID: PMC2077033 10/31/2007       84 Citations
  • Incorporation of the hydrophobic probe N-t-BOC-L-tyrosine tert-butyl ester to red blood cell membranes to study peroxynitrite-dependent reactions. (Romero N, Peluffo G, Bartesaghi S, Zhang H, Joseph J, Kalyanaraman B, Radi R) Chem Res Toxicol 2007 Nov;20(11):1638-48 PMID: 17941688 10/19/2007       13 Citations
  • Early detection of doxorubicin cardiomyopathy using two-dimensional strain echocardiography. (Migrino RQ, Aggarwal D, Konorev E, Brahmbhatt T, Bright M, Kalyanaraman B) Ultrasound Med Biol 2008 Feb;34(2):208-14 PMID: 17935867 PMCID: PMC2582214 10/16/2007       80 Citations
  • Statin-induced breast cancer cell death: role of inducible nitric oxide and arginase-dependent pathways. (Kotamraju S, Williams CL, Kalyanaraman B) Cancer Res 2007 Aug 01;67(15):7386-94 PMID: 17671209 08/03/2007       98 Citations
  • Iron signaling and oxidant damage. (Kalyanaraman B) Cardiovasc Toxicol 2007;7(2):92-4 PMID: 17652811 07/27/2007       19 Citations
  • Detection, characterization, and decay kinetics of ROS and thiyl adducts of mito-DEPMPO spin trap. (Hardy M, Rockenbauer A, Vásquez-Vivar J, Felix C, Lopez M, Srinivasan S, Avadhani N, Tordo P, Kalyanaraman B) Chem Res Toxicol 2007 Jul;20(7):1053-60 PMID: 17559235 PMCID: PMC4455887 06/15/2007       48 Citations
  • Mechanism of metal-independent decomposition of organic hydroperoxides and formation of alkoxyl radicals by halogenated quinones. (Zhu BZ, Zhao HT, Kalyanaraman B, Liu J, Shan GQ, Du YG, Frei B) Proc Natl Acad Sci U S A 2007 Mar 06;104(10):3698-702 PMID: 17360415 PMCID: PMC1820646 03/16/2007       51 Citations
  • Hydrogen peroxide induces nitric oxide and proteosome activity in endothelial cells: a bell-shaped signaling response. (Thomas S, Kotamraju S, Zielonka J, Harder DR, Kalyanaraman B) Free Radic Biol Med 2007 Apr 01;42(7):1049-61 PMID: 17349932 PMCID: PMC2692187 03/14/2007       55 Citations
  • Mito-DEPMPO synthesized from a novel NH2-reactive DEPMPO spin trap: a new and improved trap for the detection of superoxide. (Hardy M, Chalier F, Ouari O, Finet JP, Rockenbauer A, Kalyanaraman B, Tordo P) Chem Commun (Camb) 2007 Mar 14(10):1083-5 PMID: 17325813 02/28/2007       46 Citations
  • Reduction of hexavalent chromium by human cytochrome b5: generation of hydroxyl radical and superoxide. (Borthiry GR, Antholine WE, Kalyanaraman B, Myers JM, Myers CR) Free Radic Biol Med 2007 Mar 15;42(6):738-55; discussion 735-7 PMID: 17320757 PMCID: PMC1993546 02/27/2007       43 Citations
  • Increased arginase activity and endothelial dysfunction in human inflammatory bowel disease. (Horowitz S, Binion DG, Nelson VM, Kanaa Y, Javadi P, Lazarova Z, Andrekopoulos C, Kalyanaraman B, Otterson MF, Rafiee P) Am J Physiol Gastrointest Liver Physiol 2007 May;292(5):G1323-36 PMID: 17218473 01/16/2007       74 Citations
  • Synthesis and ESR studies of a novel cyclic nitrone spin trap attached to a phosphonium group-a suitable trap for mitochondria-generated ROS? (Xu Y, Kalyanaraman B) Free Radic Res 2007 Jan;41(1):1-7 PMID: 17164173 12/14/2006       35 Citations
  • Pulse radiolysis and steady-state analyses of the reaction between hydroethidine and superoxide and other oxidants. (Zielonka J, Sarna T, Roberts JE, Wishart JF, Kalyanaraman B) Arch Biochem Biophys 2006 Dec 01;456(1):39-47 PMID: 17081495 PMCID: PMC2270254 11/04/2006       46 Citations
  • Protein tyrosine nitration in hydrophilic and hydrophobic environments. (Bartesaghi S, Ferrer-Sueta G, Peluffo G, Valez V, Zhang H, Kalyanaraman B, Radi R) Amino Acids 2007;32(4):501-15 PMID: 17077966 11/02/2006       100 Citations
  • The confounding effects of light, sonication, and Mn(III)TBAP on quantitation of superoxide using hydroethidine. (Zielonka J, Vasquez-Vivar J, Kalyanaraman B) Free Radic Biol Med 2006 Oct 01;41(7):1050-7 PMID: 16962930 09/12/2006       40 Citations
  • Mechanistic studies of peroxynitrite-mediated tyrosine nitration in membranes using the hydrophobic probe N-t-BOC-L-tyrosine tert-butyl ester. (Bartesaghi S, Valez V, Trujillo M, Peluffo G, Romero N, Zhang H, Kalyanaraman B, Radi R) Biochemistry 2006 Jun 06;45(22):6813-25 PMID: 16734418 06/01/2006       67 Citations
  • Endothelial cell superoxide anion radical generation is not dependent on endothelial nitric oxide synthase-serine 1179 phosphorylation and endothelial nitric oxide synthase dimer/monomer distribution. (Whitsett J, Martásek P, Zhao H, Schauer DW, Hatakeyama K, Kalyanaraman B, Vásquez-Vivar J) Free Radic Biol Med 2006 Jun 01;40(11):2056-68 PMID: 16716906 05/24/2006       32 Citations
  • Cyclooxygenase 2 rescues LNCaP prostate cancer cells from sanguinarine-induced apoptosis by a mechanism involving inhibition of nitric oxide synthase activity. (Huh J, Liepins A, Zielonka J, Andrekopoulos C, Kalyanaraman B, Sorokin A) Cancer Res 2006 Apr 01;66(7):3726-36 PMID: 16585199 04/06/2006       42 Citations
  • Upregulation of immunoproteasomes by nitric oxide: potential antioxidative mechanism in endothelial cells. (Kotamraju S, Matalon S, Matsunaga T, Shang T, Hickman-Davis JM, Kalyanaraman B) Free Radic Biol Med 2006 Mar 15;40(6):1034-44 PMID: 16540399 03/17/2006       62 Citations
  • Nitric oxide, proteasomal function, and iron homeostasis--implications in aging and neurodegenerative diseases. (Kotamraju S, Kalivendi S, Shang T, Kalyanaraman B) Methods Enzymol 2005;396:526-34 PMID: 16291259 11/18/2005       5 Citations
  • Hydrophobic tyrosyl probes for monitoring nitration reactions in membranes. (Zhang H, Joseph J, Kalyanaraman B) Methods Enzymol 2005;396:182-204 PMID: 16291233 11/18/2005       4 Citations
  • Sepiapterin attenuates 1-methyl-4-phenylpyridinium-induced apoptosis in neuroblastoma cells transfected with neuronal NOS: role of tetrahydrobiopterin, nitric oxide, and proteasome activation. (Shang T, Kotamraju S, Zhao H, Kalivendi SV, Hillard CJ, Kalyanaraman B) Free Radic Biol Med 2005 Oct 15;39(8):1059-74 PMID: 16198233 10/04/2005       24 Citations
  • Intramolecular electron transfer between tyrosyl radical and cysteine residue inhibits tyrosine nitration and induces thiyl radical formation in model peptides treated with myeloperoxidase, H2O2, and NO2-: EPR SPIN trapping studies. (Zhang H, Xu Y, Joseph J, Kalyanaraman B) J Biol Chem 2005 Dec 09;280(49):40684-98 PMID: 16176930 09/24/2005       60 Citations
  • Mechanistic similarities between oxidation of hydroethidine by Fremy's salt and superoxide: stopped-flow optical and EPR studies. (Zielonka J, Zhao H, Xu Y, Kalyanaraman B) Free Radic Biol Med 2005 Oct 01;39(7):853-63 PMID: 16140206 09/06/2005       69 Citations
  • Motor neuron degeneration promotes neural progenitor cell proliferation, migration, and neurogenesis in the spinal cords of amyotrophic lateral sclerosis mice. (Chi L, Ke Y, Luo C, Li B, Gozal D, Kalyanaraman B, Liu R) Stem Cells 2006 Jan;24(1):34-43 PMID: 16099995 PMCID: PMC1828038 08/16/2005       100 Citations
  • Death-associated protein kinase as a sensor of mitochondrial membrane potential: role of lysosome in mitochondrial toxin-induced cell death. (Shang T, Joseph J, Hillard CJ, Kalyanaraman B) J Biol Chem 2005 Oct 14;280(41):34644-53 PMID: 16085644 08/09/2005       30 Citations
  • Mitochondria superoxide dismutase mimetic inhibits peroxide-induced oxidative damage and apoptosis: role of mitochondrial superoxide. (Dhanasekaran A, Kotamraju S, Karunakaran C, Kalivendi SV, Thomas S, Joseph J, Kalyanaraman B) Free Radic Biol Med 2005 Sep 01;39(5):567-83 PMID: 16085176 08/09/2005       149 Citations
  • Identification of residues essential for carbohydrate recognition and cation dependence of the 46-kDa mannose 6-phosphate receptor. (Sun G, Zhao H, Kalyanaraman B, Dahms NM) Glycobiology 2005 Nov;15(11):1136-49 PMID: 15972892 06/24/2005       21 Citations
  • Peroxynitrite-derived carbonate and nitrogen dioxide radicals readily react with lipoic and dihydrolipoic acid. (Trujillo M, Folkes L, Bartesaghi S, Kalyanaraman B, Wardman P, Radi R) Free Radic Biol Med 2005 Jul 15;39(2):279-88 PMID: 15964519 06/21/2005       36 Citations
  • Reductive activation of Cr(Vi) by nitric oxide synthase. (Porter R, Jáchymová M, Martásek P, Kalyanaraman B, Vásquez-Vivar J) Chem Res Toxicol 2005 May;18(5):834-43 PMID: 15892577 05/17/2005       14 Citations
  • Detection and characterization of the product of hydroethidine and intracellular superoxide by HPLC and limitations of fluorescence. (Zhao H, Joseph J, Fales HM, Sokoloski EA, Levine RL, Vasquez-Vivar J, Kalyanaraman B) Proc Natl Acad Sci U S A 2005 Apr 19;102(16):5727-32 PMID: 15824309 PMCID: PMC556312 04/13/2005       396 Citations
  • Evaluation of spin trapping agents and trapping conditions for detection of cell-generated reactive oxygen species. (Shi H, Timmins G, Monske M, Burdick A, Kalyanaraman B, Liu Y, Clément JL, Burchiel S, Liu KJ) Arch Biochem Biophys 2005 May 01;437(1):59-68 PMID: 15820217 04/12/2005       65 Citations
  • Doxorubicin activates nuclear factor of activated T-lymphocytes and Fas ligand transcription: role of mitochondrial reactive oxygen species and calcium. (Kalivendi SV, Konorev EA, Cunningham S, Vanamala SK, Kaji EH, Joseph J, Kalyanaraman B) Biochem J 2005 Jul 15;389(Pt 2):527-39 PMID: 15799720 PMCID: PMC1175131 04/01/2005       122 Citations
  • Thiol oxidase activity of copper, zinc superoxide dismutase stimulates bicarbonate-dependent peroxidase activity via formation of a carbonate radical. (Karunakaran C, Zhang H, Joseph J, Antholine WE, Kalyanaraman B) Chem Res Toxicol 2005 Mar;18(3):494-500 PMID: 15777089 03/22/2005       21 Citations
  • Changes in tetrahydrobiopterin levels in endothelial cells and adult cardiomyocytes induced by LPS and hydrogen peroxide--a role for GFRP? (Kalivendi S, Hatakeyama K, Whitsett J, Konorev E, Kalyanaraman B, Vásquez-Vivar J) Free Radic Biol Med 2005 Feb 15;38(4):481-91 PMID: 15649650 01/15/2005       36 Citations
  • Mass spectral evidence for carbonate-anion-radical-induced posttranslational modification of tryptophan to kynurenine in human Cu, Zn superoxide dismutase. (Zhang H, Joseph J, Crow J, Kalyanaraman B) Free Radic Biol Med 2004 Dec 15;37(12):2018-26 PMID: 15544920 11/17/2004       29 Citations
  • Nitrated lipids: a class of cell-signaling molecules. (Kalyanaraman B) Proc Natl Acad Sci U S A 2004 Aug 10;101(32):11527-8 PMID: 15292510 PMCID: PMC511014 08/05/2004       53 Citations
  • Supplementation of endothelial cells with mitochondria-targeted antioxidants inhibit peroxide-induced mitochondrial iron uptake, oxidative damage, and apoptosis. (Dhanasekaran A, Kotamraju S, Kalivendi SV, Matsunaga T, Shang T, Keszler A, Joseph J, Kalyanaraman B) J Biol Chem 2004 Sep 03;279(36):37575-87 PMID: 15220329 06/29/2004       171 Citations
  • Impact of pulmonary arterial endothelial cells on duroquinone redox status. (Merker MP, Bongard RD, Krenz GS, Zhao H, Fernandes VS, Kalyanaraman B, Hogg N, Audi SH) Free Radic Biol Med 2004 Jul 01;37(1):86-103 PMID: 15183197 06/09/2004       13 Citations
  • The carbonate radical anion-induced covalent aggregation of human copper, zinc superoxide dismutase, and alpha-synuclein: intermediacy of tryptophan- and tyrosine-derived oxidation products. (Zhang H, Andrekopoulos C, Joseph J, Crow J, Kalyanaraman B) Free Radic Biol Med 2004 Jun 01;36(11):1355-65 PMID: 15135171 05/12/2004       59 Citations
  • Direct probing of copper active site and free radical formed during bicarbonate-dependent peroxidase activity of bovine and human copper, zinc-superoxide dismutases. Low-temperature electron paramagnetic resonance and electron nuclear double resonance studies. (Karunakaran C, Zhang H, Crow JP, Antholine WE, Kalyanaraman B) J Biol Chem 2004 Jul 30;279(31):32534-40 PMID: 15123612 05/05/2004       28 Citations
  • Ceramide-induced intracellular oxidant formation, iron signaling, and apoptosis in endothelial cells: protective role of endogenous nitric oxide. (Matsunaga T, Kotamraju S, Kalivendi SV, Dhanasekaran A, Joseph J, Kalyanaraman B) J Biol Chem 2004 Jul 02;279(27):28614-24 PMID: 15102832 04/23/2004       70 Citations
  • Doxorubicin induces apoptosis in normal and tumor cells via distinctly different mechanisms. intermediacy of H(2)O(2)- and p53-dependent pathways. (Wang S, Konorev EA, Kotamraju S, Joseph J, Kalivendi S, Kalyanaraman B) J Biol Chem 2004 Jun 11;279(24):25535-43 PMID: 15054096 04/01/2004       350 Citations
  • Oxidant-induced iron signaling in Doxorubicin-mediated apoptosis. (Kotamraju S, Kalivendi SV, Konorev E, Chitambar CR, Joseph J, Kalyanaraman B) Methods Enzymol 2004;378:362-82 PMID: 15038980 03/25/2004       55 Citations
  • Nitric oxide mitigates peroxide-induced iron-signaling, oxidative damage, and apoptosis in endothelial cells: role of proteasomal function? (Kotamraju S, Tampo Y, Kalivendi SV, Joseph J, Chitambar CR, Kalyanaraman B) Arch Biochem Biophys 2004 Mar 01;423(1):74-80 PMID: 14989268 03/03/2004       16 Citations
  • 1-Methyl-4-phenylpyridinium-induced apoptosis in cerebellar granule neurons is mediated by transferrin receptor iron-dependent depletion of tetrahydrobiopterin and neuronal nitric-oxide synthase-derived superoxide. (Shang T, Kotamraju S, Kalivendi SV, Hillard CJ, Kalyanaraman B) J Biol Chem 2004 Apr 30;279(18):19099-112 PMID: 14752097 01/31/2004       49 Citations
  • Alpha-synuclein up-regulation and aggregation during MPP+-induced apoptosis in neuroblastoma cells: intermediacy of transferrin receptor iron and hydrogen peroxide. (Kalivendi SV, Cunningham S, Kotamraju S, Joseph J, Hillard CJ, Kalyanaraman B) J Biol Chem 2004 Apr 09;279(15):15240-7 PMID: 14742448 01/27/2004       103 Citations
  • Bicarbonate enhances alpha-synuclein oligomerization and nitration: intermediacy of carbonate radical anion and nitrogen dioxide radical. (Andrekopoulos C, Zhang H, Joseph J, Kalivendi S, Kalyanaraman B) Biochem J 2004 Mar 01;378(Pt 2):435-47 PMID: 14640973 PMCID: PMC1223984 12/03/2003       31 Citations
  • Comparative investigation of superoxide trapping by cyclic nitrone spin traps: the use of singular value decomposition and multiple linear regression analysis. (Keszler A, Kalyanaraman B, Hogg N) Free Radic Biol Med 2003 Nov 01;35(9):1149-57 PMID: 14572617 10/24/2003       53 Citations
  • Rapid-onset endothelial dysfunction with adriamycin: evidence for a dysfunctional nitric oxide synthase. (Duquaine D, Hirsch GA, Chakrabarti A, Han Z, Kehrer C, Brook R, Joseph J, Schott A, Kalyanaraman B, Vasquez-Vivar J, Rajagopalan S) Vasc Med 2003 May;8(2):101-7 PMID: 14518612 10/02/2003       42 Citations
  • Nitric oxide inhibits H2O2-induced transferrin receptor-dependent apoptosis in endothelial cells: Role of ubiquitin-proteasome pathway. (Kotamraju S, Tampo Y, Keszler A, Chitambar CR, Joseph J, Haas AL, Kalyanaraman B) Proc Natl Acad Sci U S A 2003 Sep 16;100(19):10653-8 PMID: 12958216 PMCID: PMC196859 09/06/2003       87 Citations
  • Mitochondrial sources of H2O2 generation play a key role in flow-mediated dilation in human coronary resistance arteries. (Liu Y, Zhao H, Li H, Kalyanaraman B, Nicolosi AC, Gutterman DD) Circ Res 2003 Sep 19;93(6):573-80 PMID: 12919951 08/16/2003       231 Citations
  • Reactive oxygen species induce reversible PECAM-1 tyrosine phosphorylation and SHP-2 binding. (Maas M, Wang R, Paddock C, Kotamraju S, Kalyanaraman B, Newman PJ, Newman DK) Am J Physiol Heart Circ Physiol 2003 Dec;285(6):H2336-44 PMID: 12893640 08/02/2003       21 Citations
  • Mechanisms of endotoxin tolerance in human intestinal microvascular endothelial cells. (Ogawa H, Rafiee P, Heidemann J, Fisher PJ, Johnson NA, Otterson MF, Kalyanaraman B, Pritchard KA Jr, Binion DG) J Immunol 2003 Jun 15;170(12):5956-64 PMID: 12794122 06/10/2003       54 Citations
  • Spin traps: in vitro toxicity and stability of radical adducts. (Khan N, Wilmot CM, Rosen GM, Demidenko E, Sun J, Joseph J, O'Hara J, Kalyanaraman B, Swartz HM) Free Radic Biol Med 2003 Jun 01;34(11):1473-81 PMID: 12757857 05/22/2003       98 Citations
  • Superoxide reacts with hydroethidine but forms a fluorescent product that is distinctly different from ethidium: potential implications in intracellular fluorescence detection of superoxide. (Zhao H, Kalivendi S, Zhang H, Joseph J, Nithipatikom K, Vásquez-Vivar J, Kalyanaraman B) Free Radic Biol Med 2003 Jun 01;34(11):1359-68 PMID: 12757846 05/22/2003       548 Citations
  • NO adducts in mammalian red blood cells: too much or too little? (Rassaf T, Bryan NS, Maloney RE, Specian V, Kelm M, Kalyanaraman B, Rodriguez J, Feelisch M) Nat Med 2003 May;9(5):481-2; author reply 482-3 PMID: 12724738 05/02/2003       122 Citations
  • Bicarbonate-dependent peroxidase activity of human Cu,Zn-superoxide dismutase induces covalent aggregation of protein: intermediacy of tryptophan-derived oxidation products. (Zhang H, Andrekopoulos C, Joseph J, Chandran K, Karoui H, Crow JP, Kalyanaraman B) J Biol Chem 2003 Jun 27;278(26):24078-89 PMID: 12686560 04/11/2003       92 Citations
  • 1-Methyl-4-phenylpyridinium accumulates in cerebellar granule neurons via organic cation transporter 3. (Shang T, Uihlein AV, Van Asten J, Kalyanaraman B, Hillard CJ) J Neurochem 2003 Apr;85(2):358-67 PMID: 12675912 04/05/2003       61 Citations
  • Pulmonary arterial endothelial cells affect the redox status of coenzyme Q0. (Audi SH, Zhao H, Bongard RD, Hogg N, Kettenhofen NJ, Kalyanaraman B, Dawson CA, Merker MP) Free Radic Biol Med 2003 Apr 01;34(7):892-907 PMID: 12654478 03/26/2003       17 Citations
  • The role of tetrahydrobiopterin in superoxide generation from eNOS: enzymology and physiological implications. (Vásquez-Vivar J, Kalyanaraman B, Martásek P) Free Radic Res 2003 Feb;37(2):121-7 PMID: 12653200 03/26/2003       161 Citations
  • 1-Methyl-4-phenylpyridinium (MPP+)-induced apoptosis and mitochondrial oxidant generation: role of transferrin-receptor-dependent iron and hydrogen peroxide. (Kalivendi SV, Kotamraju S, Cunningham S, Shang T, Hillard CJ, Kalyanaraman B) Biochem J 2003 Apr 01;371(Pt 1):151-64 PMID: 12523938 PMCID: PMC1223270 01/14/2003       80 Citations
  • Oxidative stress-induced iron signaling is responsible for peroxide-dependent oxidation of dichlorodihydrofluorescein in endothelial cells: role of transferrin receptor-dependent iron uptake in apoptosis. (Tampo Y, Kotamraju S, Chitambar CR, Kalivendi SV, Keszler A, Joseph J, Kalyanaraman B) Circ Res 2003 Jan 10;92(1):56-63 PMID: 12522121 01/11/2003       123 Citations
  • Transmembrane nitration of hydrophobic tyrosyl peptides. Localization, characterization, mechanism of nitration, and biological implications. (Zhang H, Bhargava K, Keszler A, Feix J, Hogg N, Joseph J, Kalyanaraman B) J Biol Chem 2003 Mar 14;278(11):8969-78 PMID: 12519728 01/10/2003       57 Citations
  • Altered tetrahydrobiopterin metabolism in atherosclerosis: implications for use of oxidized tetrahydrobiopterin analogues and thiol antioxidants. (Vásquez-Vivar J, Duquaine D, Whitsett J, Kalyanaraman B, Rajagopalan S) Arterioscler Thromb Vasc Biol 2002 Oct 01;22(10):1655-61 PMID: 12377745 10/16/2002       105 Citations
  • Paradoxical effects of metalloporphyrins on doxorubicin-induced apoptosis: scavenging of reactive oxygen species versus induction of heme oxygenase-1. (Konorev EA, Kotamraju S, Zhao H, Kalivendi S, Joseph J, Kalyanaraman B) Free Radic Biol Med 2002 Oct 01;33(7):988 PMID: 12361808 10/04/2002       52 Citations
  • Nitration of PECAM-1 ITIM tyrosines abrogates phosphorylation and SHP-2 binding. (Newman DK, Hoffman S, Kotamraju S, Zhao T, Wakim B, Kalyanaraman B, Newman PJ) Biochem Biophys Res Commun 2002 Sep 06;296(5):1171-9 PMID: 12207897 09/05/2002       32 Citations
  • Doxorubicin-induced apoptosis: implications in cardiotoxicity. (Kalyanaraman B, Joseph J, Kalivendi S, Wang S, Konorev E, Kotamraju S) Mol Cell Biochem 2002 May-Jun;234-235(1-2):119-24 PMID: 12162424 08/07/2002       267 Citations
  • Activation of nuclear factor-kappaB during doxorubicin-induced apoptosis in endothelial cells and myocytes is pro-apoptotic: the role of hydrogen peroxide. (Wang S, Kotamraju S, Konorev E, Kalivendi S, Joseph J, Kalyanaraman B) Biochem J 2002 Nov 01;367(Pt 3):729-40 PMID: 12139490 PMCID: PMC1222928 07/26/2002       178 Citations
  • The ratio between tetrahydrobiopterin and oxidized tetrahydrobiopterin analogues controls superoxide release from endothelial nitric oxide synthase: an EPR spin trapping study. (Vásquez-Vivar J, Martásek P, Whitsett J, Joseph J, Kalyanaraman B) Biochem J 2002 Mar 15;362(Pt 3):733-9 PMID: 11879202 PMCID: PMC1222439 03/07/2002       223 Citations
  • Metal-independent production of hydroxyl radicals by halogenated quinones and hydrogen peroxide: an ESR spin trapping study. (Zhu BZ, Zhao HT, Kalyanaraman B, Frei B) Free Radic Biol Med 2002 Mar 01;32(5):465-73 PMID: 11864786 02/28/2002       87 Citations
  • Transferrin receptor-dependent iron uptake is responsible for doxorubicin-mediated apoptosis in endothelial cells: role of oxidant-induced iron signaling in apoptosis. (Kotamraju S, Chitambar CR, Kalivendi SV, Joseph J, Kalyanaraman B) J Biol Chem 2002 May 10;277(19):17179-87 PMID: 11856741 02/22/2002       127 Citations
  • Bicarbonate enhances nitration and oxidation reactions in biological systems--role of reactive oxygen and nitrogen species. (Kalyanaraman B, Joseph J, Zhang H) Adv Exp Med Biol 2001;500:175-82 PMID: 11764932 01/05/2002       5 Citations
  • Antioxidant mechanisms of isoflavones in lipid systems: paradoxical effects of peroxyl radical scavenging. (Patel RP, Boersma BJ, Crawford JH, Hogg N, Kirk M, Kalyanaraman B, Parks DA, Barnes S, Darley-Usmar V) Free Radic Biol Med 2001 Dec 15;31(12):1570-81 PMID: 11744331 12/18/2001       134 Citations
  • (-)-Epicatechin inhibits nitration and dimerization of tyrosine in hydrophilic as well as hydrophobic environments. (Schroeder P, Zhang H, Klotz LO, Kalyanaraman B, Sies H) Biochem Biophys Res Commun 2001 Dec 21;289(5):1334-8 PMID: 11741342 12/14/2001       28 Citations
  • Bicarbonate enhances peroxidase activity of Cu,Zn-superoxide dismutase. Role of carbonate anion radical and scavenging of carbonate anion radical by metalloporphyrin antioxidant enzyme mimetics. (Zhang H, Joseph J, Gurney M, Becker D, Kalyanaraman B) J Biol Chem 2002 Jan 11;277(2):1013-20 PMID: 11682485 10/30/2001       84 Citations
  • Reaction of tetrahydrobiopterin with superoxide: EPR-kinetic analysis and characterization of the pteridine radical. (Vásquez-Vivar J, Whitsett J, Martásek P, Hogg N, Kalyanaraman B) Free Radic Biol Med 2001 Oct 15;31(8):975-85 PMID: 11595382 10/12/2001       91 Citations
  • Doxorubicin-induced apoptosis is associated with increased transcription of endothelial nitric-oxide synthase. Effect of antiapoptotic antioxidants and calcium. (Kalivendi SV, Kotamraju S, Zhao H, Joseph J, Kalyanaraman B) J Biol Chem 2001 Dec 14;276(50):47266-76 PMID: 11579094 10/02/2001       141 Citations
  • Synthesis and biochemical applications of a solid cyclic nitrone spin trap: a relatively superior trap for detecting superoxide anions and glutathiyl radicals. (Zhao H, Joseph J, Zhang H, Karoui H, Kalyanaraman B) Free Radic Biol Med 2001 Sep 01;31(5):599-606 PMID: 11522444 08/28/2001       247 Citations
  • Nitration and oxidation of a hydrophobic tyrosine probe by peroxynitrite in membranes: comparison with nitration and oxidation of tyrosine by peroxynitrite in aqueous solution. (Zhang H, Joseph J, Feix J, Hogg N, Kalyanaraman B) Biochemistry 2001 Jun 26;40(25):7675-86 PMID: 11412121 06/20/2001       69 Citations
  • Inhibition of oxidized low-density lipoprotein-induced apoptosis in endothelial cells by nitric oxide. Peroxyl radical scavenging as an antiapoptotic mechanism. (Kotamraju S, Hogg N, Joseph J, Keefer LK, Kalyanaraman B) J Biol Chem 2001 May 18;276(20):17316-23 PMID: 11278975 03/30/2001       62 Citations
  • Nitric oxide activates the sarcolemmal K(ATP) channel in normoxic and chronically hypoxic hearts by a cyclic GMP-dependent mechanism. (Baker JE, Contney SJ, Singh R, Kalyanaraman B, Gross GJ, Bosnjak ZJ) J Mol Cell Cardiol 2001 Feb;33(2):331-41 PMID: 11162137 02/13/2001       37 Citations
  • Chronic myocardial hypoxia increases nitric oxide synthase and decreases caveolin-3. (Shi Y, Pritchard KA Jr, Holman P, Rafiee P, Griffith OW, Kalyanaraman B, Baker JE) Free Radic Biol Med 2000 Oct 15;29(8):695-703 PMID: 11053770 10/29/2000       61 Citations
  • Bicarbonate exacerbates oxidative injury induced by antitumor antibiotic doxorubicin in cardiomyocytes. (Konorev EA, Zhang H, Joseph J, Kennedy MC, Kalyanaraman B) Am J Physiol Heart Circ Physiol 2000 Nov;279(5):H2424-30 PMID: 11045980 10/25/2000       16 Citations
  • Generation of superoxide from nitric oxide synthase. (Vásquez-Vivar J, Kalyanaraman B) FEBS Lett 2000 Sep 22;481(3):305-6 PMID: 11041680 10/21/2000       31 Citations
  • Chromium (VI) increases endothelial cell expression of ICAM-1 and decreases nitric oxide activity. (Pritchard KA Jr, Ackerman A, Kalyanaraman B) J Environ Pathol Toxicol Oncol 2000;19(3):251-60 PMID: 10983891 09/13/2000       31 Citations
  • Modification of creatine kinase by S-nitrosothiols: S-nitrosation vs. S-thiolation. (Konorev EA, Kalyanaraman B, Hogg N) Free Radic Biol Med 2000 Jun 01;28(11):1671-8 PMID: 10938464 08/12/2000       60 Citations
  • The use of NO gas in biological systems. (Hogg N, Kalyanaraman B) Methods Mol Biol 1998;100:231-6 PMID: 10907008 07/25/2000       7 Citations
  • Doxorubicin-induced apoptosis in endothelial cells and cardiomyocytes is ameliorated by nitrone spin traps and ebselen. Role of reactive oxygen and nitrogen species. (Kotamraju S, Konorev EA, Joseph J, Kalyanaraman B) J Biol Chem 2000 Oct 27;275(43):33585-92 PMID: 10899161 07/19/2000       291 Citations
  • Peroxynitrite reversibly inhibits Ca(2+)-activated K(+) channels in rat cerebral artery smooth muscle cells. (Brzezinska AK, Gebremedhin D, Chilian WM, Kalyanaraman B, Elliott SJ) Am J Physiol Heart Circ Physiol 2000 Jun;278(6):H1883-90 PMID: 10843885 06/14/2000       93 Citations
  • Detection of superoxide anion using an isotopically labeled nitrone spin trap: potential biological applications. (Zhang H, Joseph J, Vasquez-Vivar J, Karoui H, Nsanzumuhire C, Martásek P, Tordo P, Kalyanaraman B) FEBS Lett 2000 May 04;473(1):58-62 PMID: 10802059 05/10/2000       139 Citations
  • Mitochondrial aconitase is a source of hydroxyl radical. An electron spin resonance investigation. (Vasquez-Vivar J, Kalyanaraman B, Kennedy MC) J Biol Chem 2000 May 12;275(19):14064-9 PMID: 10799480 05/09/2000       214 Citations
  • Bicarbonate enhances the hydroxylation, nitration, and peroxidation reactions catalyzed by copper, zinc superoxide dismutase. Intermediacy of carbonate anion radical. (Zhang H, Joseph J, Felix C, Kalyanaraman B) J Biol Chem 2000 May 12;275(19):14038-45 PMID: 10799477 05/09/2000       97 Citations
  • Effect of redox-active drugs on superoxide generation from nitric oxide synthases: biological and toxicological implications. (Vásquez-Vivar J, Hogg N, Martásek P, Karoui H, Tordo P, Pritchard KA Jr, Kalyanaraman B) Free Radic Res 1999 Dec;31(6):607-17 PMID: 10630684 01/12/2000       26 Citations
  • Reactions of *NO, *NO2 and peroxynitrite in membranes: physiological implications. (Goss SP, Singh RJ, Hogg N, Kalyanaraman B) Free Radic Res 1999 Dec;31(6):597-606 PMID: 10630683 01/12/2000       47 Citations
  • Mechanism of superoxide dismutase/H(2)O(2)-mediated nitric oxide release from S-nitrosoglutathione--role of glutamate. (Singh RJ, Hogg N, Goss SP, Antholine WE, Kalyanaraman B) Arch Biochem Biophys 1999 Dec 01;372(1):8-15 PMID: 10562411 11/24/1999       27 Citations
  • Bicarbonate enhances the peroxidase activity of Cu,Zn-superoxide dismutase. Role of carbonate anion radical. (Goss SP, Singh RJ, Kalyanaraman B) J Biol Chem 1999 Oct 01;274(40):28233-9 PMID: 10497178 09/25/1999       79 Citations
  • Tetrahydrobiopterin-dependent inhibition of superoxide generation from neuronal nitric oxide synthase. (Vásquez-Vivar J, Hogg N, Martásek P, Karoui H, Pritchard KA Jr, Kalyanaraman B) J Biol Chem 1999 Sep 17;274(38):26736-42 PMID: 10480877 09/10/1999       154 Citations
  • Cell-permeable superoxide dismutase and glutathione peroxidase mimetics afford superior protection against doxorubicin-induced cardiotoxicity: the role of reactive oxygen and nitrogen intermediates. (Konorev EA, Kennedy MC, Kalyanaraman B) Arch Biochem Biophys 1999 Aug 15;368(2):421-8 PMID: 10441396 08/12/1999       113 Citations
  • Adaptation to chronic hypoxia confers tolerance to subsequent myocardial ischemia by increased nitric oxide production. (Baker JE, Holman P, Kalyanaraman B, Griffith OW, Pritchard KA Jr) Ann N Y Acad Sci 1999 Jun 30;874:236-53 PMID: 10415535 07/23/1999       56 Citations
  • Biochemical characterization of human S-nitrosohemoglobin. Effects on oxygen binding and transnitrosation. (Patel RP, Hogg N, Spencer NY, Kalyanaraman B, Matalon S, Darley-Usmar VM) J Biol Chem 1999 May 28;274(22):15487-92 PMID: 10336440 05/21/1999       121 Citations
  • Nitric oxide and lipid peroxidation. (Hogg N, Kalyanaraman B) Biochim Biophys Acta 1999 May 05;1411(2-3):378-84 PMID: 10320670 05/13/1999       253 Citations
  • Characterization of the adduct formed from the reaction between homocysteine thiolactone and low-density lipoprotein: antioxidant implications. (Ferguson E, Hogg N, Antholine WE, Joseph J, Singh RJ, Parthasarathy S, Kalyanaraman B) Free Radic Biol Med 1999 Apr;26(7-8):968-77 PMID: 10232841 05/08/1999       31 Citations
  • The effect of alpha-tocopherol on the nitration of gamma-tocopherol by peroxynitrite. (Goss SP, Hogg N, Kalyanaraman B) Arch Biochem Biophys 1999 Mar 15;363(2):333-40 PMID: 10068456 03/09/1999       62 Citations
  • Electron spin resonance spin-trapping detection of superoxide generated by neuronal nitric oxide synthase. (Vásquez-Vivar J, Martásek P, Hogg N, Karoui H, Masters BS, Pritchard KA Jr, Kalyanaraman B) Methods Enzymol 1999;301:169-77 PMID: 9919565 01/27/1999       35 Citations
  • Antioxidant effects of nitric oxide and nitric oxide donor compounds on low-density lipoprotein oxidation. (Goss SP, Kalyanaraman B, Hogg N) Methods Enzymol 1999;301:444-53 PMID: 9919593 01/27/1999       24 Citations
  • Adaptation of hearts to chronic hypoxia increases tolerance to subsequent ischemia by increased nitric oxide production. (Baker JE, Holman P, Kalyanaraman B, Pritchard KA Jr) Adv Exp Med Biol 1998;454:203-17 PMID: 9889894 01/16/1999       11 Citations
  • The peroxynitrite generator, SIN-1, becomes a nitric oxide donor in the presence of electron acceptors. (Singh RJ, Hogg N, Joseph J, Konorev E, Kalyanaraman B) Arch Biochem Biophys 1999 Jan 15;361(2):331-9 PMID: 9882464 01/12/1999       104 Citations
  • Depletion of nitric oxide causes cell cycle alterations, apoptosis, and oxidative stress in pulmonary cells. (Janssen YM, Soultanakis R, Steece K, Heerdt E, Singh RJ, Joseph J, Kalyanaraman B) Am J Physiol 1998 Dec;275(6 Pt 1):L1100-9 PMID: 9843847 12/09/1998       53 Citations
  • Nitration of gamma-tocopherol and oxidation of alpha-tocopherol by copper-zinc superoxide dismutase/H2O2/NO2-: role of nitrogen dioxide free radical. (Singh RJ, Goss SP, Joseph J, Kalyanaraman B) Proc Natl Acad Sci U S A 1998 Oct 27;95(22):12912-7 PMID: 9789014 PMCID: PMC23652 10/28/1998       71 Citations
  • Nitric oxide and low-density lipoprotein oxidation. (Hogg N, Kalyanaraman B) Free Radic Res 1998 Jun;28(6):593-600 PMID: 9736311 09/15/1998       26 Citations
  • Superoxide generation by endothelial nitric oxide synthase: the influence of cofactors. (Vásquez-Vivar J, Kalyanaraman B, Martásek P, Hogg N, Masters BS, Karoui H, Tordo P, Pritchard KA Jr) Proc Natl Acad Sci U S A 1998 Aug 04;95(16):9220-5 PMID: 9689061 PMCID: PMC21319 08/05/1998       1115 Citations
  • Electron spin resonance analysis of heme-nitrosyl and reduced iron-sulfur centered complexes in allogeneic, heterotopic cardiac transplants: effects of treatment with pyrrolidine dithiocarbamate. (Nakanishi AL, Roza AM, Adams MB, Seibel R, Moore-Hilton G, Kalyanaraman B, Pieper GM) Free Radic Biol Med 1998 Jul 15;25(2):201-7 PMID: 9667497 07/17/1998       17 Citations
  • Reexamination of the mechanism of hydroxyl radical adducts formed from the reaction between familial amyotrophic lateral sclerosis-associated Cu,Zn superoxide dismutase mutants and H2O2. (Singh RJ, Karoui H, Gunther MR, Beckman JS, Mason RP, Kalyanaraman B) Proc Natl Acad Sci U S A 1998 Jun 09;95(12):6675-80 PMID: 9618471 PMCID: PMC22595 06/17/1998       104 Citations
  • Rapid and irreversible inhibition of creatine kinase by peroxynitrite. (Konorev EA, Hogg N, Kalyanaraman B) FEBS Lett 1998 May 08;427(2):171-4 PMID: 9607305 06/02/1998       124 Citations
  • Generation and initial characterization of a novel polyclonal antibody directed against homocysteine thiolactone-modified low density lipoprotein. (Ferguson E, Parthasarathy S, Joseph J, Kalyanaraman B) J Lipid Res 1998 Apr;39(4):925-33 PMID: 9555955 04/29/1998       45 Citations
  • Endothelial cells prevent accumulation of lipid hydroperoxides in low-density lipoprotein. (Smalley DM, Hogg N, Kalyanaraman B, Pritchard KA Jr) Arterioscler Thromb Vasc Biol 1997 Dec;17(12):3469-74 PMID: 9437194 01/23/1998       9 Citations
  • Endothelial nitric oxide synthase-dependent superoxide generation from adriamycin. (Vásquez-Vivar J, Martasek P, Hogg N, Masters BS, Pritchard KA Jr, Kalyanaraman B) Biochemistry 1997 Sep 23;36(38):11293-7 PMID: 9333325 10/23/1997       251 Citations
  • The effect of nitric oxide release rates on the oxidation of human low density lipoprotein. (Goss SP, Hogg N, Kalyanaraman B) J Biol Chem 1997 Aug 22;272(34):21647-53 PMID: 9261188 08/22/1997       65 Citations
  • Spin-trapping of free radicals formed during the oxidation of glutathione by tetramethylammonium peroxynitrite. (Karoui H, Hansert B, Sand PJ, Tordo P, Bohle DS, Kalyanaraman B) Nitric Oxide 1997 Aug;1(4):346-58 PMID: 9441906 08/01/1997       7 Citations
  • The mechanism of apolipoprotein B-100 thiol depletion during oxidative modification of low-density lipoprotein. (Ferguson E, Singh RJ, Hogg N, Kalyanaraman B) Arch Biochem Biophys 1997 May 15;341(2):287-94 PMID: 9169017 05/15/1997       21 Citations
  • S-Nitrosoglutathione as a substrate for gamma-glutamyl transpeptidase. (Hogg N, Singh RJ, Konorev E, Joseph J, Kalyanaraman B) Biochem J 1997 Apr 15;323 ( Pt 2):477-81 PMID: 9163341 PMCID: PMC1218344 04/15/1997       114 Citations
  • Superoxide anion formation from lucigenin: an electron spin resonance spin-trapping study. (Vásquez-Vivar J, Hogg N, Pritchard KA Jr, Martasek P, Kalyanaraman B) FEBS Lett 1997 Feb 17;403(2):127-30 PMID: 9042951 02/17/1997       182 Citations
  • Spin label oximetry to assess extracellular oxygen during myocardial ischemia. (Baker JE, Froncisz W, Joseph J, Kalyanaraman B) Free Radic Biol Med 1997;22(1-2):109-15 PMID: 8958135 01/01/1997       22 Citations
  • Nitric oxide: a prostaglandin H synthase 1 and 2 reducing cosubstrate that does not stimulate cyclooxygenase activity or prostaglandin H synthase expression in murine macrophages. (Curtis JF, Reddy NG, Mason RP, Kalyanaraman B, Eling TE) Arch Biochem Biophys 1996 Nov 15;335(2):369-76 PMID: 8914934 11/15/1996       60 Citations
  • Detection of thiyl radical adducts formed during hydroxyl radical- and peroxynitrite-mediated oxidation of thiols--a high resolution ESR spin-trapping study at Q-band (35 GHz). (Kalyanaraman B, Karoui H, Singh RJ, Felix CC) Anal Biochem 1996 Oct 01;241(1):75-81 PMID: 8921168 10/01/1996       41 Citations
  • The mechanism of cardioprotection by S-nitrosoglutathione monoethyl ester in rat isolated heart during cardioplegic ischaemic arrest. (Konorev EA, Joseph J, Tarpey MM, Kalyanaraman B) Br J Pharmacol 1996 Oct;119(3):511-8 PMID: 8894171 PMCID: PMC1915698 10/01/1996       41 Citations
  • Mechanism of nitric oxide release from S-nitrosothiols. (Singh RJ, Hogg N, Joseph J, Kalyanaraman B) J Biol Chem 1996 Aug 02;271(31):18596-603 PMID: 8702510 08/02/1996       439 Citations
  • The reaction between nitric oxide and alpha-tocopherol: a reappraisal. (Hogg N, Singh RJ, Goss SP, Kalyanaraman B) Biochem Biophys Res Commun 1996 Jul 25;224(3):696-702 PMID: 8713109 07/25/1996       23 Citations
  • Effect of superoxide dismutase mimics on radical adduct formation during the reaction between peroxynitrite and thiols--an ESR-spin trapping study. (Karoui H, Hogg N, Joseph J, Kalyanaraman B) Arch Biochem Biophys 1996 Jun 01;330(1):115-24 PMID: 8651684 06/01/1996       14 Citations
  • The role of glutathione in the transport and catabolism of nitric oxide. (Hogg N, Singh RJ, Kalyanaraman B) FEBS Lett 1996 Mar 18;382(3):223-8 PMID: 8605974 03/18/1996       230 Citations
  • Characterization of sulfur-centered radical intermediates formed during the oxidation of thiols and sulfite by peroxynitrite. ESR-spin trapping and oxygen uptake studies. (Karoui H, Hogg N, Fréjaville C, Tordo P, Kalyanaraman B) J Biol Chem 1996 Mar 15;271(11):6000-9 PMID: 8626383 03/15/1996       193 Citations
  • S-nitrosoglutathione induces formation of nitrosylmyoglobin in isolated hearts during cardioplegic ischemia--an electron spin resonance study. (Konorev EA, Joseph J, Kalyanaraman B) FEBS Lett 1996 Jan 08;378(2):111-4 PMID: 8549814 01/08/1996       22 Citations
  • Detection of nitric oxide by electron spin resonance in chemical, photochemical, cellular, physiological, and pathophysiological systems. (Kalyanaraman B) Methods Enzymol 1996;268:168-87 PMID: 8782583 01/01/1996       50 Citations
  • Interaction of nitric oxide with photoexcited rose bengal: evidence for one-electron reduction of nitric oxide to nitroxyl anion. (Singh RJ, Hogg N, Kalyanaraman B) Arch Biochem Biophys 1995 Dec 20;324(2):367-73 PMID: 8554328 12/20/1995       8 Citations
  • Nitric oxide inhibition of lipoxygenase-dependent liposome and low-density lipoprotein oxidation: termination of radical chain propagation reactions and formation of nitrogen-containing oxidized lipid derivatives. (Rubbo H, Parthasarathy S, Barnes S, Kirk M, Kalyanaraman B, Freeman BA) Arch Biochem Biophys 1995 Dec 01;324(1):15-25 PMID: 7503550 12/01/1995       206 Citations
  • Inhibition of macrophage-dependent low density lipoprotein oxidation by nitric-oxide donors. (Hogg N, Struck A, Goss SP, Santanam N, Joseph J, Parthasarathy S, Kalyanaraman B) J Lipid Res 1995 Aug;36(8):1756-62 PMID: 7595096 08/01/1995       74 Citations
  • Detection by ESR of DMPO hydroxyl adduct formation from islets of Langerhans. (Pieper GM, Felix CC, Kalyanaraman B, Turk M, Roza AM) Free Radic Biol Med 1995 Aug;19(2):219-25 PMID: 7649493 08/01/1995       31 Citations
  • Radical intermediates during degradation of lignin-model compounds and environmental pollutants: an electron spin resonance study. (Kalyanaraman B) Xenobiotica 1995 Jul;25(7):667-75 PMID: 7483665 07/01/1995       19 Citations
  • The antioxidant effect of spermine NONOate in human low-density lipoprotein. (Goss SP, Hogg N, Kalyanaraman B) Chem Res Toxicol 1995 Jul-Aug;8(5):800-6 PMID: 7548764 07/01/1995       49 Citations
  • S-nitrosoglutathione improves functional recovery in the isolated rat heart after cardioplegic ischemic arrest-evidence for a cardioprotective effect of nitric oxide. (Konorev EA, Tarpey MM, Joseph J, Baker JE, Kalyanaraman B) J Pharmacol Exp Ther 1995 Jul;274(1):200-6 PMID: 7616400 07/01/1995       76 Citations
  • Spin-labeling study of the oxidative damage to low-density lipoprotein. (Singh RJ, Feix JB, Mchaourab HS, Hogg N, Kalyanaraman B) Arch Biochem Biophys 1995 Jun 20;320(1):155-61 PMID: 7793976 06/20/1995       23 Citations
  • Is free radical generation an important component of ischemia/reperfusion injury? Part 2. (Kalyanaraman B, Konorev EA, Joseph J, Baker JE) Redox Rep 1995 May;1(3):181-4 PMID: 27414273 05/01/1995    
  • Role of apolipoprotein B-derived radical and alpha-tocopheroxyl radical in peroxidase-dependent oxidation of low density lipoprotein. (Kalyanaraman B, Darley-Usmar V, Struck A, Hogg N, Parthasarathy S) J Lipid Res 1995 May;36(5):1037-45 PMID: 7658151 05/01/1995       38 Citations
  • Trapping of nitric oxide formed during photolysis of sodium nitroprusside in aqueous and lipid phases: an electron spin resonance study. (Singh RJ, Hogg N, Neese F, Joseph J, Kalyanaraman B) Photochem Photobiol 1995 Apr;61(4):325-30 PMID: 7740075 04/01/1995       41 Citations
  • Nitric oxide donor compounds inhibit the toxicity of oxidized low-density lipoprotein to endothelial cells. (Struck AT, Hogg N, Thomas JP, Kalyanaraman B) FEBS Lett 1995 Mar 20;361(2-3):291-4 PMID: 7698340 03/20/1995       58 Citations
  • Photosensitized decomposition of S-nitrosothiols and 2-methyl-2-nitrosopropane. Possible use for site-directed nitric oxide production. (Singh RJ, Hogg N, Joseph J, Kalyanaraman B) FEBS Lett 1995 Feb 20;360(1):47-51 PMID: 7875299 02/20/1995       60 Citations
  • Nitronyl nitroxides as probes to study the mechanism of vasodilatory action of nitrovasodilators, nitrone spin traps, and nitroxides: role of nitric oxide. (Konorev EA, Tarpey MM, Joseph J, Baker JE, Kalyanaraman B) Free Radic Biol Med 1995 Feb;18(2):169-77 PMID: 7744299 02/01/1995       35 Citations
  • Thiyl radicals in biological systems: significant or trivial? (Kalyanaraman B) Biochem Soc Symp 1995;61:55-63 PMID: 8660403 01/01/1995       34 Citations
  • Reactions of nitric oxide with nitronyl nitroxides and oxygen: prediction of nitrite and nitrate formation by kinetic simulation. (Hogg N, Singh RJ, Joseph J, Neese F, Kalyanaraman B) Free Radic Res 1995 Jan;22(1):47-56 PMID: 7889147 01/01/1995       67 Citations
  • Physical and chemical interactions between nitric oxide and nitroxides. (Singh RJ, Hogg N, Mchaourab HS, Kalyanaraman B) Biochim Biophys Acta 1994 Dec 15;1201(3):437-41 PMID: 7803474 12/15/1994       22 Citations
  • Involvement of preexisting lipid hydroperoxides in Cu(2+)-stimulated oxidation of low-density lipoprotein. (Thomas JP, Kalyanaraman B, Girotti AW) Arch Biochem Biophys 1994 Dec;315(2):244-54 PMID: 7986064 12/01/1994    
  • Multiple mechanisms for inhibition of low density lipoprotein oxidation by novel cyclic nitrone spin traps. (Thomas CE, Ohlweiler DF, Kalyanaraman B) J Biol Chem 1994 Nov 11;269(45):28055-61 PMID: 7961741 11/11/1994       25 Citations
  • Nitric oxide regulation of superoxide and peroxynitrite-dependent lipid peroxidation. Formation of novel nitrogen-containing oxidized lipid derivatives. (Rubbo H, Radi R, Trujillo M, Telleri R, Kalyanaraman B, Barnes S, Kirk M, Freeman BA) J Biol Chem 1994 Oct 21;269(42):26066-75 PMID: 7929318 10/21/1994       1140 Citations
  • The oxidation of alpha-tocopherol and trolox by peroxynitrite. (Hogg N, Joseph J, Kalyanaraman B) Arch Biochem Biophys 1994 Oct;314(1):153-8 PMID: 7944387 10/01/1994    
  • Enhancement of merocyanine 540 uptake and photodynamic cell killing by salicylates. (Feix JB, Anderson MS, Kalyanaraman B) Cancer Res 1994 Jul 01;54(13):3474-8 PMID: 8012969 07/01/1994       4 Citations
  • Nitrone spin trap lipophilicity as a determinant for inhibition of low density lipoprotein oxidation and activation of interleukin-1 beta release from human monocytes. (Thomas CE, Ku G, Kalyanaraman B) J Lipid Res 1994 Apr;35(4):610-9 PMID: 8006515 04/01/1994       17 Citations
  • Lack of protection of PBN in isolated heart during ischemia and reperfusion: implications for radical scavenging mechanism. (Baker JE, Konorev EA, Tse SY, Joseph J, Kalyanaraman B) Free Radic Res 1994 Mar;20(3):145-63 PMID: 8019639 03/01/1994       10 Citations
  • Inhibition of low-density lipoprotein oxidation by nitric oxide. Potential role in atherogenesis. (Hogg N, Kalyanaraman B, Joseph J, Struck A, Parthasarathy S) FEBS Lett 1993 Nov 15;334(2):170-4 PMID: 8224243 11/15/1993       345 Citations
  • Peroxynitrite modification of low-density lipoprotein leads to recognition by the macrophage scavenger receptor. (Graham A, Hogg N, Kalyanaraman B, O'Leary V, Darley-Usmar V, Moncada S) FEBS Lett 1993 Sep 13;330(2):181-5 PMID: 8365489 09/13/1993       244 Citations
  • Spin trapping of nitrogen dioxide radical from photolytic decomposition of nitramines. (Pace MD, Kalyanaraman B) Free Radic Biol Med 1993 Sep;15(3):337-42 PMID: 8406133 09/01/1993       14 Citations
  • Site-specific trapping of reactive species in low-density lipoprotein oxidation: biological implications. (Kalyanaraman B, Joseph J, Parthasarathy S) Biochim Biophys Acta 1993 Jun 12;1168(2):220-7 PMID: 8389205 06/12/1993       12 Citations
  • Free radicals in toxicology. (Aust SD, Chignell CF, Bray TM, Kalyanaraman B, Mason RP) Toxicol Appl Pharmacol 1993 Jun;120(2):168-78 PMID: 8511786 06/01/1993    
  • The use of spin traps to investigate site-specific formation of free radicals in low-density lipoprotein oxidation. (Kalyanaraman B, Joseph J, Parthasarathy S) Biochem Soc Trans 1993 May;21(2):318-21 PMID: 8395423 05/01/1993       11 Citations
  • Trapping of nitric oxide by nitronyl nitroxides: an electron spin resonance investigation. (Joseph J, Kalyanaraman B, Hyde JS) Biochem Biophys Res Commun 1993 Apr 30;192(2):926-34 PMID: 8387295 04/30/1993    
  • Enhancement of merocyanine 540-mediated phototherapy by salicylate. (Anderson MS, Kalyanaraman B, Feix JB) Cancer Res 1993 Feb 15;53(4):806-9 PMID: 8381329 02/15/1993       10 Citations
  • Vasodilatory and toxic effects of spin traps on aerobic cardiac function. (Konorev EA, Baker JE, Joseph J, Kalyanaraman B) Free Radic Biol Med 1993 Feb;14(2):127-37 PMID: 8425719 02/01/1993       64 Citations
  • Intracellular catalase inhibition does not predispose rat heart to ischemia-reperfusion and hydrogen peroxide-induced injuries. (Konorev EA, Struck AT, Baker JE, Ramanujam S, Thomas JP, Radi R, Kalyanaraman B) Free Radic Res Commun 1993;19(6):397-407 PMID: 8168729 01/01/1993       11 Citations
  • Direct modification of low density lipoprotein by the spin trap 3,5-dibromo-4-nitrosobenzenesulfonic acid. (Kalyanaraman B, Joseph J, Kondratenko N, Parthasarathy S) Biochim Biophys Acta 1992 Jun 26;1126(3):309-13 PMID: 1322177 06/26/1992       10 Citations
  • Evidence for the formation of a quinone methide during the oxidation of the insect cuticular sclerotizing precursor 1,2-dehydro-N-acetyldopamine. (Sugumaran M, Semensi V, Kalyanaraman B, Bruce JM, Land EJ) J Biol Chem 1992 May 25;267(15):10355-61 PMID: 1316899 05/25/1992       51 Citations
  • Synergistic interaction between the probucol phenoxyl radical and ascorbic acid in inhibiting the oxidation of low density lipoprotein. (Kalyanaraman B, Darley-Usmar VM, Wood J, Joseph J, Parthasarathy S) J Biol Chem 1992 Apr 05;267(10):6789-95 PMID: 1313022 04/05/1992       72 Citations
  • Photobleaching of merocyanine 540: involvement of singlet molecular oxygen. (Singh RJ, Feix JB, Kalyanaraman B) Photochem Photobiol 1992 Apr;55(4):483-9 PMID: 1620725 04/01/1992       22 Citations
  • Production of singlet oxygen-derived hydroxyl radical adducts during merocyanine-540-mediated photosensitization: analysis by ESR-spin trapping and HPLC with electrochemical detection. (Feix JB, Kalyanaraman B) Arch Biochem Biophys 1991 Nov 15;291(1):43-51 PMID: 1656888 11/15/1991       63 Citations
  • Action spectra of the antileukemic and antiviral activities of merocyanine 540. (O'Brien JM, Singh RJ, Feix JB, Kalyanaraman B, Sieber F) Photochem Photobiol 1991 Nov;54(5):851-4 PMID: 1665914 11/01/1991       19 Citations
  • Xanthine oxidase-catalyzed reduction of estrogen quinones to semiquinones and hydroquinones. (Roy D, Kalyanaraman B, Liehr JG) Biochem Pharmacol 1991 Sep 27;42(8):1627-31 PMID: 1656992 09/27/1991       24 Citations
  • Detection of radical adducts of 5,5-dimethyl-1-pyrroline n-oxide by the combined use of high-performance liquid chromatography with electrochemical detection and electron spin resonance. (Towell J, Kalyanaraman B) Anal Biochem 1991 Jul;196(1):111-9 PMID: 1653547 07/01/1991       32 Citations
  • An electron paramagnetic resonance study of the interactions between the adriamycin semiquinone, hydrogen peroxide, iron-chelators, and radical scavengers. (Kalyanaraman B, Morehouse KM, Mason RP) Arch Biochem Biophys 1991 Apr;286(1):164-70 PMID: 1654778 04/01/1991       51 Citations
  • Photodynamic action of merocyanine 540 in artificial bilayers and natural membranes: action spectra and quantum yields. (Singh RJ, Feix JB, Pintar TJ, Girotti AW, Kalyanaraman B) Photochem Photobiol 1991 Apr;53(4):493-500 PMID: 1857744 04/01/1991       37 Citations
  • Characterization of the pigment from homogentisic acid and urine and tissue from an alkaptonuria patient. (Menon IA, Persad SD, Haberman HF, Basu PK, Norfray JF, Felix CC, Kalyanaraman B) Biochem Cell Biol 1991 Apr;69(4):269-73 PMID: 1647170 04/01/1991       20 Citations
  • The spin trap, alpha-phenyl N-tert-butylnitrone, inhibits the oxidative modification of low density lipoprotein. (Kalyanaraman B, Joseph J, Parthasarathy S) FEBS Lett 1991 Mar 11;280(1):17-20 PMID: 1849092 03/11/1991    
  • An electron spin resonance study of merocyanine 540-mediated type I reactions in liposomes. (Feix JB, Kalyanaraman B) Photochem Photobiol 1991 Jan;53(1):39-45 PMID: 1851304 01/01/1991       18 Citations
  • Effects of hydroxyethyl starch conjugated deferoxamine on myocardial functional recovery following coronary occlusion and reperfusion in dogs. (Maruyama M, Pieper GM, Kalyanaraman B, Hallaway PE, Hedlund BE, Gross GJ) J Cardiovasc Pharmacol 1991 Jan;17(1):166-75 PMID: 1708051 01/01/1991       28 Citations
  • Spin-trapping studies of the oxidation-reduction reactions of iron bleomycin in the presence of thiols and buffer. (Antholine WE, Kalyanaraman B, Templin JA, Byrnes RW, Petering DH) Free Radic Biol Med 1991;10(2):119-23 PMID: 1707847 01/01/1991       21 Citations
  • Lignin peroxidase oxidation of Mn2+ in the presence of veratryl alcohol, malonic or oxalic acid, and oxygen. (Popp JL, Kalyanaraman B, Kirk TK) Biochemistry 1990 Nov 20;29(46):10475-80 PMID: 2176868 11/20/1990       107 Citations
  • Copper ion-dependent oxy-radical mediated DNA damage from dihydroxy derivative of etoposide. (Sinha BK, Antholine WM, Kalyanaraman B, Eliot HM) Biochim Biophys Acta 1990 Nov 14;1096(1):81-3 PMID: 2176549 11/14/1990       18 Citations
  • Oxidation of low-density lipoprotein by Cu2+ and lipoxygenase: an electron spin resonance study. (Kalyanaraman B, Antholine WE, Parthasarathy S) Biochim Biophys Acta 1990 Sep 14;1035(3):286-92 PMID: 2169886 09/14/1990       41 Citations
  • Characterization of radical adducts formed during photochemical spin trapping in liposomes. (Sheng PG, Feix J, Kalyanaraman B) Photochem Photobiol 1990 Aug;52(2):323-31 PMID: 2171003 08/01/1990       4 Citations
  • Comparison of lignin peroxidase, horseradish peroxidase and laccase in the oxidation of methoxybenzenes. (Kersten PJ, Kalyanaraman B, Hammel KE, Reinhammar B, Kirk TK) Biochem J 1990 Jun 01;268(2):475-80 PMID: 2163614 PMCID: PMC1131457 06/01/1990       273 Citations
  • On the detection of paramagnetic species in the adriamycin-perfused rat heart: a reappraisal. (Kalyanaraman B, Baker JE) Biochem Biophys Res Commun 1990 May 31;169(1):30-8 PMID: 2161659 05/31/1990       2 Citations
  • An ESR study of the nitroxide radical of pentastarch-conjugated deferoxamine. (Pieper GM, Gross GJ, Kalyanaraman B) Free Radic Biol Med 1990;9(3):211-8 PMID: 2177027 01/01/1990       11 Citations
  • Characterization of o-semiquinone radicals in biological systems. (Kalyanaraman B) Methods Enzymol 1990;186:333-43 PMID: 2172710 01/01/1990       49 Citations
  • Spin trapping of lipid-derived radicals in liposomes. (Feix JB, Kalyanaraman B) Biochim Biophys Acta 1989 Aug 18;992(2):230-5 PMID: 2547451 08/18/1989       17 Citations
  • Evidence for the metabolism of tumor promoter organic hydroperoxides into free radicals by human carcinoma skin keratinocytes: an ESR-spin trapping study. (Athar M, Mukhtar H, Bickers DR, Khan IU, Kalyanaraman B) Carcinogenesis 1989 Aug;10(8):1499-503 PMID: 2473853 08/01/1989       54 Citations
  • Characterization of semiquinone free radicals formed from stilbene catechol estrogens. An ESR spin stabilization and spin trapping study. (Kalyanaraman B, Sealy RC, Liehr JG) J Biol Chem 1989 Jul 05;264(19):11014-9 PMID: 2544580 07/05/1989       26 Citations
  • Characterization of free radicals produced during oxidation of etoposide (VP-16) and its catechol and quinone derivatives. An ESR Study. (Kalyanaraman B, Nemec J, Sinha BK) Biochemistry 1989 May 30;28(11):4839-46 PMID: 2548593 05/30/1989       70 Citations
  • Ischemia-induced changes in myocardial paramagnetic metabolites: implications for intracellular oxy-radical generation. (Baker JE, Kalyanaraman B) FEBS Lett 1989 Feb 27;244(2):311-4 PMID: 2537756 02/27/1989       42 Citations
  • Direct observation of singlet oxygen production by merocyanine 540 associated with phosphatidylcholine liposomes. (Feix JB, Kalyanaraman B, Chignell CF, Hall RD) J Biol Chem 1988 Nov 25;263(33):17247-50 PMID: 3182846 11/25/1988       39 Citations
  • Reaction between ortho-semiquinones and oxygen: pulse radiolysis, electron spin resonance, and oxygen uptake studies. (Kalyanaraman B, Korytowski W, Pilas B, Sarna T, Land EJ, Truscott TG) Arch Biochem Biophys 1988 Oct;266(1):277-84 PMID: 2845864 10/01/1988       34 Citations
  • Oxygen activation during the interaction between MPTP metabolites and synthetic neuromelanin--an ESR-spin trapping, optical, and oxidase electrode study. (Korytowski W, Felix CC, Kalyanaraman B) Biochem Biophys Res Commun 1988 Jul 29;154(2):781-8 PMID: 2840906 07/29/1988       11 Citations
  • Ligninase-mediated phenoxy radical formation and polymerization unaffected by cellobiose:quinone oxidoreductase. (Odier E, Mozuch MD, Kalyanaraman B, Kirk TK) Biochimie 1988 Jun;70(6):847-52 PMID: 2844307 06/01/1988       46 Citations
  • Myocardial ischemia and reperfusion: direct evidence for free radical generation by electron spin resonance spectroscopy. (Baker JE, Felix CC, Olinger GN, Kalyanaraman B) Proc Natl Acad Sci U S A 1988 Apr;85(8):2786-9 PMID: 2833754 PMCID: PMC280084 04/01/1988       183 Citations
  • Mechanism of oxidation of 1-methyl-4-phenyl-3,3-dihydropyridinium (MPDP+). (Kalyanaraman B, Korytowski W, Felix CC) Basic Life Sci 1988;49:781-5 PMID: 3250532 01/01/1988    
  • The production of hydroxyl and semiquinone free radicals during the autoxidation of redox active flavonoids. (Hodnick WF, Kalyanaraman B, Pritsos CA, Pardini RS) Basic Life Sci 1988;49:149-52 PMID: 2854978 01/01/1988       33 Citations
  • The effect of melanin on iron associated decomposition of hydrogen peroxide. (Pilas B, Sarna T, Kalyanaraman B, Swartz HM) Free Radic Biol Med 1988;4(5):285-93 PMID: 2834276 01/01/1988       109 Citations
  • Serial spousal directed blood donations. (Kolins MD) Transfusion 1987 Nov-Dec;27(6):503 PMID: 3686663 11/01/1987    
  • Evidence for the one-electron oxidation of 1-methyl-4-phenyl-2,3-dihydropyridinium (MPDP+). (Korytowski W, Felix CC, Kalyanaraman B) Biochem Biophys Res Commun 1987 Aug 31;147(1):354-60 PMID: 3632675 08/31/1987       8 Citations
  • Semiquinone anion radicals from addition of amino acids, peptides, and proteins to quinones derived from oxidation of catechols and catecholamines. An ESR spin stabilization study. (Kalyanaraman B, Premovic PI, Sealy RC) J Biol Chem 1987 Aug 15;262(23):11080-7 PMID: 3038907 08/15/1987       131 Citations
  • Is there any difference in the photobiological properties of melanins isolated from human blue and brown eyes? (Menon IA, Basu PK, Persad S, Avaria M, Felix CC, Kalyanaraman B) Br J Ophthalmol 1987 Jul;71(7):549-52 PMID: 2820463 PMCID: PMC1041224 07/01/1987    
  • Tyrosinase-catalyzed oxidation of dopa and related catechol(amine)s: a kinetic electron spin resonance investigation using spin-stabilization and spin label oximetry. (Korytowski W, Sarna T, Kalyanaraman B, Sealy RC) Biochim Biophys Acta 1987 Jun 22;924(3):383-92 PMID: 3036239 06/22/1987       64 Citations
  • Photodynamic action of merocyanine 540 on artificial and natural cell membranes: involvement of singlet molecular oxygen. (Kalyanaraman B, Feix JB, Sieber F, Thomas JP, Girotti AW) Proc Natl Acad Sci U S A 1987 May;84(9):2999-3003 PMID: 3033673 PMCID: PMC304788 05/01/1987       163 Citations
  • Mechanism of oxidation of 1-methyl-4-phenyl-2,3-dihydropyridinium (MPDP+). (Korytowski W, Felix CC, Kalyanaraman B) Biochem Biophys Res Commun 1987 Apr 29;144(2):692-8 PMID: 3579936 04/29/1987       14 Citations
  • Photoinduced generation of hydrogen peroxide and hydroxyl radicals in melanins. (Korytowski W, Pilas B, Sarna T, Kalyanaraman B) Photochem Photobiol 1987 Feb;45(2):185-90 PMID: 3031709 02/01/1987       130 Citations
  • Interactions of the antitumor drug, etoposide, with reduced thiols in vitro and in vivo. (Katki AG, Kalyanaraman B, Sinha BK) Chem Biol Interact 1987;62(3):237-47 PMID: 3040275 01/01/1987       30 Citations
  • Effects of diazepam on human laboratory aggression: correlations with alcohol effects and hostility measures. (Cherek DR, Steinberg JL, Kelly TH) NIDA Res Monogr 1987;76:95-101 PMID: 3125473 01/01/1987       2 Citations
  • Oxidation of polycyclic aromatic hydrocarbons and dibenzo[p]-dioxins by Phanerochaete chrysosporium ligninase. (Hammel KE, Kalyanaraman B, Kirk TK) J Biol Chem 1986 Dec 25;261(36):16948-52 PMID: 3023375 12/25/1986       323 Citations
  • The use of spin label oximetry in the study of photodynamic inactivation of Chinese hamster ovary cells. (Ankel E, Felix CC, Kalyanaraman B) Photochem Photobiol 1986 Dec;44(6):741-6 PMID: 3031706 12/01/1986       2 Citations
  • Photolysis of pheomelanin precursors: an ESR-spin trapping study. (Pilas B, Felix CC, Sarna T, Kalyanaraman B) Photochem Photobiol 1986 Dec;44(6):689-96 PMID: 3031704 12/01/1986       15 Citations
  • An electron spin resonance study of free radicals from catechol estrogens. (Kalyanaraman B, Hintz P, Sealy RC) Fed Proc 1986 Sep;45(10):2477-84 PMID: 3017766 09/01/1986       16 Citations
  • Metal ion-induced activation of molecular oxygen in pigmented polymers. (Hintz P, Kalyanaraman B) Biochim Biophys Acta 1986 Aug 06;883(1):41-5 PMID: 3015234 08/06/1986       17 Citations
  • Reaction of superoxide anions with melanins: electron spin resonance and spin trapping studies. (Korytowski W, Kalyanaraman B, Menon IA, Sarna T, Sealy RC) Biochim Biophys Acta 1986 Jun 19;882(2):145-53 PMID: 3011111 06/19/1986       94 Citations
  • Substrate free radicals are intermediates in ligninase catalysis. (Hammel KE, Kalyanaraman B, Kirk TK) Proc Natl Acad Sci U S A 1986 Jun;83(11):3708-12 PMID: 3012530 PMCID: PMC323592 06/01/1986       69 Citations
  • Ligninase of Phanerochaete chrysosporium. Mechanism of its degradation of the non-phenolic arylglycerol beta-aryl ether substructure of lignin. (Kirk TK, Tien M, Kersten PJ, Mozuch MD, Kalyanaraman B) Biochem J 1986 May 15;236(1):279-87 PMID: 3024619 PMCID: PMC1146817 05/15/1986    
  • ESR of copper and iron complexes with antitumor and cytotoxic properties. (Antholine WE, Kalyanaraman B, Petering DH) Environ Health Perspect 1985 Dec;64:19-35 PMID: 2420582 PMCID: PMC1568621 12/01/1985       45 Citations
  • Semiquinone anion radicals of catechol(amine)s, catechol estrogens, and their metal ion complexes. (Kalyanaraman B, Felix CC, Sealy RC) Environ Health Perspect 1985 Dec;64:185-98 PMID: 3007089 PMCID: PMC1568593 12/01/1985       124 Citations
  • Free radical-mediated activation of hydrazine derivatives. (Kalyanaraman B, Sinha BK) Environ Health Perspect 1985 Dec;64:179-84 PMID: 3007088 PMCID: PMC1568606 12/01/1985       41 Citations
  • Mechanism of DNA strand breaks by mitonafide, an imide derivative of 3-nitro-1,8-naphthalic acid. (Sinha BK, Strong J, Gibson NW, Kalyanaraman B) Biochem Pharmacol 1985 Nov 01;34(21):3845-52 PMID: 4062959 11/01/1985       9 Citations
  • Mechanism of dismutation of superoxide produced during autoxidation of melanin pigments. (Korytowski W, Hintz P, Sealy RC, Kalyanaraman B) Biochem Biophys Res Commun 1985 Sep 16;131(2):659-65 PMID: 2996521 09/16/1985       49 Citations
  • Mechanism of oxidative C alpha-C beta cleavage of a lignin model dimer by Phanerochaete chrysosporium ligninase. Stoichiometry and involvement of free radicals. (Hammel KE, Tien M, Kalyanaraman B, Kirk TK) J Biol Chem 1985 Jul 15;260(14):8348-53 PMID: 2989288 07/15/1985       123 Citations
  • Microsomal interactions and inhibition of lipid peroxidation by etoposide (VP-16, 213): implications for mode of action. (Sinha BK, Trush MA, Kalyanaraman B) Biochem Pharmacol 1985 Jun 01;34(11):2036-40 PMID: 4004921 06/01/1985       33 Citations
  • Radical anions from one-electron-reduced adrenochrome. Detection and identification by electron spin resonance spectroscopy. (Prabhananda BS, Kalyanaraman B, Sealy RC) Biochim Biophys Acta 1985 May 29;840(1):21-8 PMID: 2986709 05/29/1985       9 Citations
  • Generation of free radical intermediates from foreign compounds by neutrophil-derived oxidants. (Kalyanaraman B, Sohnle PG) J Clin Invest 1985 May;75(5):1618-22 PMID: 2987307 PMCID: PMC425503 05/01/1985       104 Citations
  • Spin trapping of the azidyl radical in azide/catalase/H2O2 and various azide/peroxidase/H2O2 peroxidizing systems. (Kalyanaraman B, Janzen EG, Mason RP) J Biol Chem 1985 Apr 10;260(7):4003-6 PMID: 2984193 04/10/1985       93 Citations
  • Free radicals from the photodecomposition of bleomycin. (Antholine WE, Sarna T, Sealy RC, Kalyanaraman B, Shields GD, Petering DH) Photochem Photobiol 1985 Apr;41(4):393-9 PMID: 2409563 04/01/1985       8 Citations
  • The ligninase of Phanerochaete chrysosporium generates cation radicals from methoxybenzenes. (Kersten PJ, Tien M, Kalyanaraman B, Kirk TK) J Biol Chem 1985 Mar 10;260(5):2609-12 PMID: 2982828 03/10/1985       271 Citations
  • An electron spin resonance study of o-semiquinones formed during the enzymatic and autoxidation of catechol estrogens. (Kalyanaraman B, Sealy RC, Sivarajah K) J Biol Chem 1984 Nov 25;259(22):14018-22 PMID: 6094535 11/25/1984       59 Citations
  • Identification by electron spin resonance spectroscopy of free radicals produced during autoxidative melanogenesis. (Sealy RC, Puzyna W, Kalyanaraman B, Felix CC) Biochim Biophys Acta 1984 Aug 21;800(3):269-76 PMID: 6087915 08/21/1984       26 Citations
  • An electron spin resonance study of the reduction of peroxides by anthracycline semiquinones. (Kalyanaraman B, Sealy RC, Sinha BK) Biochim Biophys Acta 1984 Jun 29;799(3):270-5 PMID: 6329317 06/29/1984       77 Citations
  • Peroxidatic oxidation of catecholamines. A kinetic electron spin resonance investigation using the spin stabilization approach. (Kalyanaraman B, Felix CC, Sealy RC) J Biol Chem 1984 Jun 25;259(12):7584-9 PMID: 6330064 06/25/1984       66 Citations
  • On the use of organic extraction in the spin-trapping technique as applied to biological systems. (Kalyanaraman B, Mottley C, Mason RP) J Biochem Biophys Methods 1984 Mar;9(1):27-31 PMID: 6327794 03/01/1984       24 Citations
  • Electron spin resonance-spin stabilization of semiquinones produced during oxidation of epinephrine and its analogues. (Kalyanaraman B, Felix CC, Sealy RC) J Biol Chem 1984 Jan 10;259(1):354-8 PMID: 6323406 01/10/1984       73 Citations
  • Free radical metabolism of VP-16 and inhibition of anthracycline-induced lipid peroxidation. (Sinha BK, Trush MA, Kalyanaraman B) Biochem Pharmacol 1983 Nov 15;32(22):3495-8 PMID: 6651872 11/15/1983       50 Citations
  • A free radical mediated cooxidation of tetramethylhydrazine by prostaglandin hydroperoxidase. (Kalyanaraman B, Sivarajah K, Eling TE, Mason RP) Carcinogenesis 1983 Oct;4(10):1341-3 PMID: 6311452 10/01/1983       16 Citations
  • A direct electron spin resonance and spin-trapping investigation of peroxyl free radical formation by hematin/hydroperoxide systems. (Kalyanaraman B, Mottley C, Mason RP) J Biol Chem 1983 Mar 25;258(6):3855-8 PMID: 6300059 03/25/1983       116 Citations
  • Electron spin resonance--spin stabilization in enzymatic systems: detection of semiquinones produced during peroxidatic oxidation of catechols and catecholamines. (Kalyanaraman B, Sealy RC) Biochem Biophys Res Commun 1982 Jun 30;106(4):1119-25 PMID: 6288039 06/30/1982       59 Citations
  • The free radical formed during the hydroperoxide-mediated deactivation of ram seminal vesicles is hemoprotein-derived. (Kalyanaraman B, Mason RP, Tainer B, Eling TE) J Biol Chem 1982 May 10;257(9):4764-8 PMID: 6279648 05/10/1982       54 Citations
  • An electron spin resonance study of the novel radical cation produced during the horseradish peroxidase-catalyzed oxidation of tetramethylhydrazine. (Kalyanaraman B, Mason RP, Sivarajah K) Biochem Biophys Res Commun 1982 Mar 15;105(1):217-24 PMID: 6284143 03/15/1982       11 Citations
  • [Proceedings: Effect of glucagon on biosynthesis of cholesterol in the liver]. (Ukai M, Tomura A, Ito M) Nihon Naibunpi Gakkai Zasshi 1974 Feb 20;50(2):647 PMID: 4476640 02/20/1974    
  • [Sanitary and hygienic evaluation of water desalinated by the EDUM-300-2 electrodialysis installation]. (Anan'ev NI, Demin NA) Gig Sanit 1971;36(2):89-90 PMID: 4253647 01/01/1971    
  • Last update: 02/13/2018
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