| 3 | Reutericyclin, a specialized metabolite of Limosilactobacillus reuteri, mitigates risperidone-induced weight gain in mice. (Aboulalazm FA, Kazen AB, deLeon O, Müller S, Saravia FL, Lozada-Fernandez V, Hadiono MA, Keyes RF, Smith BC, Kellogg SL, Grobe JL, Kindel TL, Kirby JR) Gut Microbes 2025 Dec;17(1):2477819 |
| 1 | Interspecies Differences in Cytomegalovirus Inhibition by Cardiac Glycosides-A Unique Role of the Alpha3 Isoform of the Na+/K+-ATPase Pump. (Mei H, Cai H, Liu F, Venkatadri R, Miller HE, Mathison AJ, Wang HL, Silva SC, O'Doherty GA, Arav-Boger R) Viruses 2025 Mar 11;17(3) |
| 1 | UNC9426, a Potent and Orally Bioavailable TYRO3-Specific Inhibitor. (Kong D, Yang X, Judd S, Yan D, Springborn S, Stashko MA, Kidwell A, Huelse JM, Kireev D, Graham DK, DeRyckere D, Branchford B, Wang X) J Med Chem 2025 Mar 27;68(6):6665-6682 |
| 1 | FFAR4 Deficiency Increases Necrotic Cores in Advanced Lesions of ApoE-/- Mice. (Stuttgen GM, Bobek J, Penoske R, Wadding-Lee C, Lam M, Hader SN, Owens Iii AP, Sahoo D) Arterioscler Thromb Vasc Biol 2025 Mar 06 |
| 1 | Alveolar epithelial paxillin in postnatal lung alveolar development. (Scheer M, Kyi P, Mammoto T, Mammoto A) Biol Open 2025 Mar 15;14(3) |
| 1 | Activity and function of the endothelial sodium channel is regulated by the effector domain of MARCKS-like protein 1 in mouse aortic endothelial cells. (Yu L, Bala N, Nguyen VL, Kessler L, LaDisa JF Jr, Alli AA) Am J Physiol Cell Physiol 2025 Apr 01;328(4):C1101-C1108 |
| 4 | Intestinal epithelium-derived IL-34 reprograms macrophages to mitigate gastrointestinal tract graft-versus-host disease. (Rayasam A, Moe A, Kudek M, Shah RK, Yuan CY, Miller JM, Rau M, Patton M, Wanat K, Colonna M, Zamora AE, Drobyski WR) Sci Transl Med 2025 Feb 12;17(785):eadn3963 1 Citation |
| 3 | Borrelia burgdorferi tolerates alteration to P66 porin function in a murine infectivity model. (Fierros CH, Faucillion ML, Hahn BL, Anderson P, Bonde M, Kessler JR, Surdel MC, Crawford KS, Gao Y, Zhu J, Bergström S, Coburn J) Front Cell Infect Microbiol 2024;14:1528456 |
| 1 | Extended repertoire of CXC chemokines acting as agonists and antagonists of the human and murine atypical chemokine receptor ACKR2. (Luís R, Volkman BF, Szpakowska M, Chevigné A) J Leukoc Biol 2025 Apr 23;117(4) |
| 1 | Scratching promotes allergic inflammation and host defense via neurogenic mast cell activation. (Liu AW, Zhang YR, Chen CS, Edwards TN, Ozyaman S, Ramcke T, McKendrick LM, Weiss ES, Gillis JE, Laughlin CR, Randhawa SK, Phelps CM, Kurihara K, Kang HM, Nguyen SN, Kim J, Sheahan TD, Ross SE, Meisel M, Sumpter TL, Kaplan DH) Science 2025 Jan 31;387(6733):eadn9390 |
| 1 | Liquid-based encapsulation for implantable bioelectronics across broad pH environments. (Sun H, Xue X, Robilotto GL, Zhang X, Son C, Chen X, Cao Y, Nan K, Yang Y, Fennell G, Jung J, Song Y, Li H, Lu SH, Liu Y, Li Y, Zhang W, He J, Wang X, Li Y, Mickle AD, Zhang Y) Nat Commun 2025 Jan 25;16(1):1019 |
| 1 | Impacts of hnRNP A1 Splicing Inhibition on the Brain Remyelination Proteome. (Brandão-Teles C, Carregari VC, Reis-de-Oliveira G, Smith BJ, Chaves Y, Sousa Santos AV, Pinheiro EMC, Oliveira CC, Vieira AS, Crunfli F, Martins-de-Souza D) J Neurochem 2025 Jan;169(1):e16304 |
| 1 | Oxidative Phosphorylation Is a Metabolic Vulnerability of Endocrine Therapy-Tolerant Persister Cells in ER+ Breast Cancer. (Tau S, Chamberlin MD, Yang H, Marotti JD, Muskus PC, Roberts AM, Carmichael MM, Cressey L, Dragnev CPC, Demidenko E, Hampsch RA, Soucy SM, Kolling FW, Samkoe KS, Alvarez JV, Kettenbach AN, Miller TW) Cancer Res 2025 Mar 14;85(6):1145-1161 |
| 1 | Inactivation of ATG13 stimulates chronic demyelinating pathologies in muscle-serving nerves and spinal cord. (Drosen ME, Bulbule S, Gottschalk G, Peterson D, Allen LA, Arnold LA, Roy A) Immunol Res 2025 Jan 07;73(1):27 |
| 1 | EZH2 deletion does not affect acinar regeneration but restricts progression to pancreatic cancer in mice. (Jaune-Pons E, Wang X, Mousavi F, Klassen Z, El Kaoutari A, Berger K, Johnson C, Martin MB, Aggarwal S, Brar S, Khalid M, Ryan JF, Shooshtari P, Mathison AJ, Dusetti N, Urrutia R, Lomberk G, Pin CL) JCI Insight 2024 Dec 31;10(3) |
| 1 | The vectors went in two-by-two: Transduction efficiency and tolerability of dual and triple rAAV vector delivery following intravitreal injection for genome-editing applications. (Fehrman RL, Chern KJ, Stoltz KP, Lipinski DM) Exp Eye Res 2025 Feb;251:110223 1 Citation |
| 1 | Intrinsic adaptive plasticity in mouse and human sensory neurons. (McIlvried LA, Del Rosario JS, Pullen MY, Wangzhou A, Sheahan TD, Shepherd AJ, Slivicki RA, Lemen JA, Price TJ, Copits BA, Gereau RW 4th) J Gen Physiol 2025 Jan 06;157(1) |
| 1 | IL-1ra and CCL5, but not IL-10, are promising targets for treating SMA astrocyte-driven pathology. (Allison RL, Mangione CC, Suneja M, Gawrys J, Melvin BM, Belous N, LaCroix M, Harmelink M, Burnett BG, Ebert AD) Mol Ther 2025 Feb 05;33(2):734-751 |
| 1 | Cardiac dysfunction and altered gene expression in acid ceramidase-deficient mice. (Kleynerman A, Rybova J, McKillop WM, Dlugi TA, Faber ML, Fuller M, O'Meara CC, Medin JA) Am J Physiol Heart Circ Physiol 2025 Jan 01;328(1):H141-H156 1 Citation |
| 1 | Increased keratinocyte activity and PIEZO1 signaling contribute to paclitaxel-induced mechanical hypersensitivity. (Mikesell AR, Isaeva E, Schulte ML, Menzel AD, Sriram A, Prahl MM, Shin SM, Sadler KE, Yu H, Stucky CL) Sci Transl Med 2024 Dec 11;16(777):eadn5629 1 Citation |
| 1 | An Alkyne-Containing Isoprenoid Analogue Based on a Farnesyl Diphosphate Scaffold Is a Biologically Functional Universal Probe for Proteomic Analysis. (Auger SA, Pedersen JS, Maity S, Sprague-Getsy AM, Lorimer EL, Koehn OJ, Krauklis SA, Berns B, Murphy KM, Hussain J, Thao P, Bernhagen K, Justyna K, Sundaresan AP, McKim DB, Williams CL, Hougland JL, Li L, Distefano MD) Biochemistry 2025 Jan 07;64(1):138-155 |
| 1 | Tetrahydrobiopterin as a rheostat of cell resistance to oxidant injury. (Traeger RS, Woodcock J, Tan S, Shi Z, Vasquez-Vivar J) Redox Biol 2025 Feb;79:103447 5 Citations |
| 1 | Serotonin 1A Receptors Modulate Serotonin 2A Receptor-Mediated Behavioral Effects of 5-Methoxy-N,N-dimethyltryptamine Analogs in Mice. (Glatfelter GC, Clark AA, Cavalco NG, Landavazo A, Partilla JS, Naeem M, Golen JA, Chadeayne AR, Manke DR, Blough BE, McCorvy JD, Baumann MH) ACS Chem Neurosci 2024 Dec 18;15(24):4458-4477 |
| 3 | Definitive Evidence for the Identification and Function of Renin-Expressing Cholinergic Neurons in the Nucleus Ambiguus. (Fekete ÉM, Gomez J, Ghobrial M, Kaminski K, Muskus PC, Boychuk CR, Hantke Guixa A, Vazirabad I, Xie M, Ganiyu A, Golosova D, Mathieu NM, Wang YB, Lu KT, Wackman KK, Brozoski DT, Mouradian GC, Hodges MR, Segar JL, Grobe JL, Sigmund CD, Nakagawa P) Hypertension 2025 Feb;82(2):282-292 |
| 1 | Integrative analysis identifies the atypical repressor E2F8 as a targetable transcriptional activator driving lethal prostate cancer. (Huang F, Li K, Chen Z, Cui Z, Hankey W, Fang K, Yan J, Wang H, Jin VX, Dong Y, Wang Q) Oncogene 2025 Mar;44(8):481-493 1 Citation |
| 2 | Glycosphingolipids and their impact on platelet activity in a murine model of fabry disease. (Kanack AJ, Prodoehl E, Ishihara-Aoki M, Aoki K, Dahms NM) Sci Rep 2024 Nov 27;14(1):29488 1 Citation |
| 1 | UBR1 Promotes Sex-Dependent ACE2 Ubiquitination in Hypertension. (Elgazzaz M, Lakkappa N, Berdasco C, Mohan UP, Nuzzo A, Restivo L, Martinez A, Scarborough A, Guidry JJ, Sriramula S, Xu J, Daoud H, Mendiola Plá MA, Bowles DE, Beyer AM, Mauvais-Jarvis F, Yue X, Filipeanu CM, Lazartigues E) Hypertension 2025 Jan;82(1):84-95 2 Citations |
| 1 | Potent and Selective Human 5-HT2B Serotonin Receptor Antagonists: 4'-Cyano-(N)-methanocarba-adenosines by Synthetic Serendipity. (Tosh DK, Pavan M, Clark AA, Lammers J, Villano S, Marri S, Sgambellone S, Choi S, Lee J, Ivancich MS, Bock HA, Campbell RG, Lewicki SA, Levitan IM, Chen E, Liu N, Demby T, Gavrilova O, Gao ZG, Lucarini L, McCorvy JD, Jacobson KA) J Med Chem 2024 Dec 12;67(23):21264-21291 1 Citation |
| 1 | IQGAP1 promotes early B cell development, is essential for the development of marginal zone (MZ) B cells, and is critical for both T-dependent and T-independent antibody responses. (Lella RK, Malarkannan S) Cell Mol Life Sci 2024 Nov 25;81(1):462 1 Citation |
| 4 | Early-life sodium restriction programs autonomic dysfunction and salt sensitivity in male C57BL/6J mice. (Ziegler AA, Lawton SBR, Fekete EM, Brozoski DT, Wagner VA, Grobe CC, Sigmund CD, Nakagawa P, Grobe JL, Segar JL) Am J Physiol Regul Integr Comp Physiol 2025 Jan 01;328(1):R109-R120 |
| 1 | IEPA, a novel radiation countermeasure, alleviates acute radiation syndrome in rodents. (Wesolowski R, Fish BL, Eibl M, Bähr S, Munjal Mehta S, Czajkowski MT, Gasperetti T, Orschell CM, Asang C, Singh N, Himburg HA, Pleimes D) Int J Radiat Biol 2025;101(1):1-14 |
| 1 | Chemokine CXCL13 facilitates anti-FVIII inhibitory antibody development in hemophilia A patients and murine models. (Luo L, An X, Wang Y, Zheng Q, Lin K, Shi Q, Chen Y) Int Immunopharmacol 2024 Dec 25;143(Pt 2):113472 |
| 2 | Regulation of hepatic inclusions and fibrinogen biogenesis by SEL1L-HRD1 ERAD. (Song Z, Thepsuwan P, Hur WS, Torres M, Wu SA, Wei X, Tushi NJ, Wei J, Ferraresso F, Paton AW, Paton JC, Zheng Z, Zhang K, Fang D, Kastrup CJ, Jaiman S, Flick MJ, Sun S) Nat Commun 2024 Oct 26;15(1):9244 2 Citations |
| 1 | The SWI/SNF subunit ARID1B is important for regenerative ability of hematopoietic stem cells in normal hematopoiesis. (Arnold O, Bluemn T, Stelloh C, Rao S, Zhu N) PLoS One 2024;19(10):e0312616 |
| 1 | Combination of proviral and antiviral roles of B cell-intrinsic STAT1 expression defines parameters of chronic gammaherpesvirus infection. (Johansen ER, Schmalzriedt DL, Avila D, Sylvester PA, Rahlf CR, Bobek JM, Sahoo D, Dittel BN, Tarakanova VL) mBio 2024 Nov 13;15(11):e0159824 1 Citation |
| 1 | MARK2 variants cause autism spectrum disorder via the downregulation of WNT/β-catenin signaling pathway. (Gong M, Li J, Qin Z, Machado Bressan Wilke MV, Liu Y, Li Q, Liu H, Liang C, Morales-Rosado JA, Cohen ASA, Hughes SS, Sullivan BR, Waddell V, van den Boogaard MH, van Jaarsveld RH, van Binsbergen E, van Gassen KL, Wang T, Hiatt SM, Amaral MD, Kelley WV, Zhao J, Feng W, Ren C, Yu Y, Boczek NJ, Ferber MJ, Lahner C, Elliott S, Ruan Y, Mignot C, Keren B, Xie H, Wang X, Popp B, Zweier C, Piard J, Coubes C, Mau-Them FT, Safraou H, Innes AM, Gauthier J, Michaud JL, Koboldt DC, Sylvie O, Willems M, Tan WH, Cogne B, Rieubland C, Braun D, McLean SD, Platzer K, Zacher P, Oppermann H, Evenepoel L, Blanc P, El Khattabi L, Haque N, Dsouza NR, Zimmermann MT, Urrutia R, Klee EW, Shen Y, Du H, Rappaport L, Liu CM, Chen X) Am J Hum Genet 2024 Nov 07;111(11):2392-2410 1 Citation |
| 1 | Maintenance of X chromosome inactivation after T cell activation requires NF-κB signaling. (Forsyth KS, Toothacre NE, Jiwrajka N, Driscoll AM, Shallberg LA, Cunningham-Rundles C, Barmettler S, Farmer J, Verbsky J, Routes J, Beiting DP, Romberg N, May MJ, Anguera MC) Sci Immunol 2024 Oct 04;9(100):eado0398 3 Citations |
| 2 | Rap1A Modulates Store-Operated Calcium Entry in the Lung Endothelium: A Novel Mechanism Controlling NFAT-Mediated Vascular Inflammation and Permeability. (Kosuru R, Romito O, Sharma GP, Ferraresso F, Ghadrdoost Nakhchi B, Yang K, Mammoto T, Mammoto A, Kastrup CJ, Zhang DX, Goldspink PH, Trebak M, Chrzanowska M) Arterioscler Thromb Vasc Biol 2024 Nov;44(11):2271-2287 2 Citations |
| 2 | Gelsolin controls the release of phosphatidylserine (PS)-positive microvesicles (MVs) from platelets. (Paul M, Hong F, Falet H, Kim H) Cell Signal 2024 Dec;124:111433 2 Citations |
| 1 | Kappa opioids inhibit spinal output neurons to suppress itch. (Sheahan TD, Warwick CA, Cui AY, Baranger DAA, Perry VJ, Smith KM, Manalo AP, Nguyen EK, Koerber HR, Ross SE) Sci Adv 2024 Sep 27;10(39):eadp6038 3 Citations |
| 1 | Dissociable dorsal medial prefrontal cortex ensembles are necessary for cocaine seeking and fear conditioning in mice. (Liu S, Nawarawong N, Liu X, Liu QS, Olsen CM) Transl Psychiatry 2024 Sep 23;14(1):387 |
| 1 | Alterations in visible light exposure modulate platelet function and regulate thrombus formation. (Andraska EA, Denorme F, Kaltenmeier C, Arivudainabi A, Mihalko EP, Dyer M, Annarapu GK, Zarisfi M, Loughran P, Ozel M, Williamson K, Mota Alvidrez RI, Thomas K, Shiva S, Shea SM, Steinman RA, Campbell RA, Rosengart MR, Neal MD) J Thromb Haemost 2025 Jan;23(1):123-138 |
| 6 | Long-term Metabolic Dysfunction Programming in Female Mice by Serial Moderate Restriction of a High-fat High-sucrose Diet. (Wildes MP, Fernando DG, Grobe CC, Reho JJ, Grobe JL, Kidambi S, Kindel TL, Kwitek AE, Segar JL, Williams JS, Morselli LL) Endocrinology 2024 Aug 27;165(10) |
| 1 | EPAS1 Attenuates Atherosclerosis Initiation at Disturbed Flow Sites Through Endothelial Fatty Acid Uptake. (Pirri D, Tian S, Tardajos-Ayllon B, Irving SE, Donati F, Allen SP, Mammoto T, Vilahur G, Kabir L, Bennett J, Rasool Y, Pericleous C, Mazzei G, McAllan L, Scott WR, Koestler T, Zingg U, Birdsey GM, Miller CL, Schenkel T, Chambers EV, Dunning MJ, Serbanovic-Canic J, Botrè F, Mammoto A, Xu S, Osto E, Han W, Fragiadaki M, Evans PC) Circ Res 2024 Sep 27;135(8):822-837 2 Citations |
| 1 | Astrocytic glutamate transport is essential for the memory-enhancing effects of 17β-estradiol in ovariectomized mice. (Taxier LR, Pillerová M, Branyan TE, Sohrabji F, Frick KM) Horm Behav 2024 Sep;165:105618 1 Citation |
| 1 | Dopaminergic progenitors generated by small molecule approach survived, integrated, and promoted functional recovery in (6-OHDA) mouse model of Parkinson's disease. (Alexanian AR, Sorokin A, Duersteler M) J Neurol Sci 2024 Oct 15;465:123188 |
| 1 | Exploring structural features of sleep-enhancing peptides derived from casein hydrolysates by chemometrics and random forest methodology. (Qian J, Yu F, Arnold LA, Saha A, Zheng L, Zhao M) Food Chem 2024 Dec 15;461:140838 4 Citations |
| 1 | Investigating the In Vivo Biodistribution of Extracellular Vesicles Isolated from Various Human Cell Sources Using Positron Emission Tomography. (Rosenkrans ZT, Thickens AS, Kink JA, Aluicio-Sarduy E, Engle JW, Hematti P, Hernandez R) Mol Pharm 2024 Sep 02;21(9):4324-4335 9 Citations |
| 1 | Expanded profiling of WD repeat domain 5 inhibitors reveals actionable strategies for the treatment of hematologic malignancies. (Meyer CT, Smith BN, Wang J, Teuscher KB, Grieb BC, Howard GC, Silver AJ, Lorey SL, Stott GM, Moore WJ, Lee T, Savona MR, Weissmiller AM, Liu Q, Quaranta V, Fesik SW, Tansey WP) Proc Natl Acad Sci U S A 2024 Aug 27;121(35):e2408889121 2 Citations |
| 2 | High mobility group box 1 (HMGB1) is a potential disease biomarker in cell and mouse models of Duchenne muscular dystrophy. (Slick RA, Sutton J, Haberman M, O'Brien BS, Tinklenberg JA, Mardikar A, Prom MJ, Beatka M, Gartz M, Vanden Avond MA, Siebers E, Mack DL, Gonzalez JP, Ebert AD, Nagaraju K, Lawlor MW) Biol Open 2024 Sep 15;13(9) |
| 1 | Evaluating clinically translatable conditioning for platelet gene therapy in murine hemophilia A with inhibitors. (Chen Y, Li J, Schroeder JA, Jing W, Shi Q) J Thromb Haemost 2024 Nov;22(11):3035-3047 |
| 3 | Neuropathic pain has sex-specific effects on oxycodone-seeking and non-drug-seeking ensemble neurons in the dorsomedial prefrontal cortex of mice. (Sarka BC, Liu S, Banerjee A, Stucky CL, Liu QS, Olsen CM) Addict Biol 2024 Aug;29(8):e13430 |
| 1 | Hematopoietic stem cell transplantation leads to biochemical and functional correction in two mouse models of acid ceramidase deficiency. (Rybova J, Sundararajan T, Kuchar L, Dlugi TA, Ruzicka P, McKillop WM, Medin JA) Mol Ther 2024 Oct 02;32(10):3402-3421 3 Citations |
| 1 | Anti-mCD20 in combination with α-mCXCL13 monoclonal antibody inhibits anti-FVIII antibody development in hemophilia A mice. (Zheng Q, Lin K, Zhang N, Shi Q, Wu Y, Chen Y) Int Immunopharmacol 2024 Sep 30;139:112735 |
| 1 | Mass Spectrometry Imaging Combined with Sparse Autoencoder Method Reveals Altered Phosphorylcholine Distribution in Imipramine Treated Wild-Type Mice Brains. (Rahman MF, Islam A, Islam MM, Mamun MA, Xu L, Sakamoto T, Sato T, Takahashi Y, Kahyo T, Aoyagi S, Kaibuchi K, Setou M) Int J Mol Sci 2024 Jul 21;25(14) 1 Citation |
| 1 | Low-dose orthotopic cancer implantation permits measurement of longitudinal functional changes associated with cachexia. (Roy I, Binder-Markey B, Willbanks A, Sychowski D, Phipps T, Barber A, McAllister D, D'Andrea D, Franz CK, Pichika R, Dwinell MB, Lieber RL) J Appl Physiol (1985) 2024 Sep 01;137(3):705-717 |
| 1 | Genetic deletion or pharmacologic inhibition of histone deacetylase 6 protects the heart against ischaemia/reperfusion injury by limiting tumour necrosis factor alpha-induced mitochondrial injury in experimental diabetes. (Baumgardt SL, Fang J, Fu X, Liu Y, Xia Z, Zhao M, Chen L, Mishra R, Gunasekaran M, Saha P, Forbess JM, Bosnjak ZJ, Camara AKS, Kersten JR, Thorp EB, Kaushal S, Ge ZD) Cardiovasc Res 2024 Oct 14;120(12):1456-1471 3 Citations |
| 1 | An efficient inducible model for the control of gene expression in renin cells. (Medrano S, Yamaguchi M, Almeida LF, Smith JP, Yamaguchi H, Sigmund CD, Sequeira-Lopez MLS, Gomez RA) Am J Physiol Renal Physiol 2024 Sep 01;327(3):F489-F503 |
| 1 | Germ line ERG haploinsufficiency defines a new syndrome with cytopenia and hematological malignancy predisposition. (Zerella JR, Homan CC, Arts P, Lin X, Spinelli SJ, Venugopal P, Babic M, Brautigan PJ, Truong L, Arriola-Martinez L, Moore S, Hollins R, Parker WT, Nguyen H, Kassahn KS, Branford S, Feurstein S, Larcher L, Sicre de Fontbrune F, Demirdas S, de Munnik S, Antoine-Poirel H, Brichard B, Mansour S, Gordon K, Wlodarski MW, Koppayi A, Dobbins S, Mutsaers PGNJ, Nichols KE, Oak N, DeMille D, Mao R, Crawford A, McCarrier J, Basel D, Flores-Daboub J, Drazer MW, Phillips K, Poplawski NK, Birdsey GM, Pirri D, Ostergaard P, Simons A, Godley LA, Ross DM, Hiwase DK, Soulier J, Brown AL, Carmichael CL, Scott HS, Hahn CN) Blood 2024 Oct 24;144(17):1765-1780 4 Citations |
| 1 | Bifunctional black phosphorus quantum dots platform: Delivery and remarkable immunotherapy enhancement of STING agonist. (Zhang Y, Wang S, Rha H, Xu C, Pei Y, Ji X, Zhang J, Lu R, Zhang S, Xie Z, Kim JS) Biomaterials 2024 Dec;311:122696 4 Citations |
| 3 | Lipid Trolling to Optimize A3 Adenosine Receptor-Positive Allosteric Modulators (PAMs). (Pradhan B, Pavan M, Fisher CL, Salmaso V, Wan TC, Keyes RF, Rollison N, Suresh RR, Kumar TS, Gao ZG, Smith BC, Auchampach JA, Jacobson KA) J Med Chem 2024 Jul 25;67(14):12221-12247 4 Citations |
| 1 | Understanding the genetic complexity of puberty timing across the allele frequency spectrum. (Kentistou KA, Kaisinger LR, Stankovic S, Vaudel M, Mendes de Oliveira E, Messina A, Walters RG, Liu X, Busch AS, Helgason H, Thompson DJ, Santoni F, Petricek KM, Zouaghi Y, Huang-Doran I, Gudbjartsson DF, Bratland E, Lin K, Gardner EJ, Zhao Y, Jia RY, Terao C, Riggan MJ, Bolla MK, Yazdanpanah M, Yazdanpanah N, Bradfield JP, Broer L, Campbell A, Chasman DI, Cousminer DL, Franceschini N, Franke LH, Girotto G, He C, Järvelin MR, Joshi PK, Kamatani Y, Karlsson R, Luan J, Lunetta KL, Mägi R, Mangino M, Medland SE, Meisinger C, Noordam R, Nutile T, Concas MP, Polašek O, Porcu E, Ring SM, Sala C, Smith AV, Tanaka T, van der Most PJ, Vitart V, Wang CA, Willemsen G, Zygmunt M, Ahearn TU, Andrulis IL, Anton-Culver H, Antoniou AC, Auer PL, Barnes CLK, Beckmann MW, Berrington de Gonzalez A, Bogdanova NV, Bojesen SE, Brenner H, Buring JE, Canzian F, Chang-Claude J, Couch FJ, Cox A, Crisponi L, Czene K, Daly MB, Demerath EW, Dennis J, Devilee P, De Vivo I, Dörk T, Dunning AM, Dwek M, Eriksson JG, Fasching PA, Fernandez-Rhodes L, Ferreli L, Fletcher O, Gago-Dominguez M, García-Closas M, García-Sáenz JA, González-Neira A, Grallert H, Guénel P, Haiman CA, Hall P, Hamann U, Hakonarson H, Hart RJ, Hickey M, Hooning MJ, Hoppe R, Hopper JL, Hottenga JJ, Hu FB, Huebner H, Hunter DJ, ABCTB Investigators, Jernström H, John EM, Karasik D, Khusnutdinova EK, Kristensen VN, Lacey JV, Lambrechts D, Launer LJ, Lind PA, Lindblom A, Magnusson PKE, Mannermaa A, McCarthy MI, Meitinger T, Menni C, Michailidou K, Millwood IY, Milne RL, Montgomery GW, Nevanlinna H, Nolte IM, Nyholt DR, Obi N, O'Brien KM, Offit K, Oldehinkel AJ, Ostrowski SR, Palotie A, Pedersen OB, Peters A, Pianigiani G, Plaseska-Karanfilska D, Pouta A, Pozarickij A, Radice P, Rennert G, Rosendaal FR, Ruggiero D, Saloustros E, Sandler DP, Schipf S, Schmidt CO, Schmidt MK, Small K, Spedicati B, Stampfer M, Stone J, Tamimi RM, Teras LR, Tikkanen E, Turman C, Vachon CM, Wang Q, Winqvist R, Wolk A, Zemel BS, Zheng W, van Dijk KW, Alizadeh BZ, Bandinelli S, Boerwinkle E, Boomsma DI, Ciullo M, Chenevix-Trench G, Cucca F, Esko T, Gieger C, Grant SFA, Gudnason V, Hayward C, Kolčić I, Kraft P, Lawlor DA, Martin NG, Nøhr EA, Pedersen NL, Pennell CE, Ridker PM, Robino A, Snieder H, Sovio U, Spector TD, Stöckl D, Sudlow C, Timpson NJ, Toniolo D, Uitterlinden A, Ulivi S, Völzke H, Wareham NJ, Widen E, Wilson JF, Lifelines Cohort Study, Danish Blood Donor Study, Ovarian Cancer Association Consortium, Breast Cancer Association Consortium, Biobank Japan Project, China Kadoorie Biobank Collaborative Group, Pharoah PDP, Li L, Easton DF, Njølstad PR, Sulem P, Murabito JM, Murray A, Manousaki D, Juul A, Erikstrup C, Stefansson K, Horikoshi M, Chen Z, Farooqi IS, Pitteloud N, Johansson S, Day FR, Perry JRB, Ong KK) Nat Genet 2024 Jul;56(7):1397-1411 9 Citations |
| 2 | Nontypeable Haemophilus influenzae challenge during gammaherpesvirus infection enhances viral reactivation and latency. (Huss NP, Majeed ST, Wills BM, Tarakanova VL, Brockman KL, Jondle CN) Virology 2024 Sep;597:110153 1 Citation |
| 2 | Estrogen-related receptor alpha promotes thyroid tumor cell survival via a tumor subtype-specific regulation of target gene networks. (Chen W, Song YS, Lee HS, Lin CW, Lee J, Kang YE, Kim SK, Kim SY, Park YJ, Park JI) Oncogene 2024 Jul;43(31):2431-2446 1 Citation |
| 1 | Elevating TPO production up a Notch. (Falet H, Hoffmeister KM) Blood 2024 Jun 27;143(26):2684-2686 |
| 1 | JP4-039, a Mitochondria-Targeted Nitroxide, Mitigates the Effect of Apoptosis and Inflammatory Cell Migration in the Irradiated Mouse Retina. (Adeghate JO, Epperly MW, Davoli KA, Lathrop KL, Wipf P, Hou W, Fisher R, Thermozier S, Huq MS, Sahel JA, Greenberger JS, Eller AW) Int J Mol Sci 2024 Jun 13;25(12) |
| 1 | Ferroptosis inhibitor improves outcome after early and delayed treatment in mild spinal cord injury. (Ryan F, Blex C, Ngo TD, Kopp MA, Michalke B, Venkataramani V, Curran L, Schwab JM, Ruprecht K, Otto C, Jhelum P, Kroner A, David S) Acta Neuropathol 2024 Jun 22;147(1):106 7 Citations |
| 1 | DART.2: bidirectional synaptic pharmacology with thousandfold cellular specificity. (Shields BC, Yan H, Lim SSX, Burwell SCV, Cammarata CM, Fleming EA, Yousefzadeh SA, Goldenshtein VZ, Kahuno EW, Vagadia PP, Loughran MH, Zhiquan L, McDonnell ME, Scalabrino ML, Thapa M, Hawley TM, Field GD, Hull C, Schiltz GE, Glickfeld LL, Reitz AB, Tadross MR) Nat Methods 2024 Jul;21(7):1288-1297 2 Citations |
| 3 | Decreased Liver Kinase B1 Expression and Impaired Angiogenesis in a Murine Model of Bronchopulmonary Dysplasia. (Rana U, Joshi C, Whitney E, Afolayan A, Dowell J, Teng RJ, Konduri GG) Am J Respir Cell Mol Biol 2024 Oct;71(4):481-494 1 Citation |
| 1 | Endoplasmic Reticulum Stress Response Mediator IRE-1α Promotes Host Dendritic Cells in Graft-versus-Host Disease Development. (Choi HJ, Wu Y, McDaniel Mims B, Pugel A, Tang CA, Tian L, Hu CA, Yu XZ) J Immunol 2024 Aug 01;213(3):384-393 |
| 1 | From bone to nanoparticles: development of a novel generation of bone derived nanoparticles for image guided orthopedic regeneration. (Stellpflug A, Walls J, Hansen C, Joshi A, Wang B) Biomater Sci 2024 Jul 09;12(14):3633-3648 1 Citation |
| 1 | Runx1 is sufficient but not required for cardiomyocyte cell-cycle activation. (Akins KA, Flinn MA, Swift SK, Chanjeevaram SV, Purdy AL, Buddell T, Kolell ME, Andresen KG, Paddock S, Buday SL, Veldman MB, O'Meara CC, Patterson M) Am J Physiol Heart Circ Physiol 2024 Aug 01;327(2):H377-H389 4 Citations |
| 1 | Preclinical Safety Assessment of Lepidium sativum L. Seed Extract and its Nanoparticles via Acute and Subacute Oral Administration. (Ahmad A, Mishra A, Nabi R, Ahmad IZ) Recent Pat Nanotechnol 2024;18(3):350-360 1 Citation |
| 1 | Determining the ERK-regulated phosphoproteome driving KRAS-mutant cancer. (Klomp JE, Diehl JN, Klomp JA, Edwards AC, Yang R, Morales AJ, Taylor KE, Drizyte-Miller K, Bryant KL, Schaefer A, Johnson JL, Huntsman EM, Yaron TM, Pierobon M, Baldelli E, Prevatte AW, Barker NK, Herring LE, Petricoin EF 3rd, Graves LM, Cantley LC, Cox AD, Der CJ, Stalnecker CA) Science 2024 Jun 07;384(6700):eadk0850 17 Citations |
| 1 | N-(4-Bromo-2,5-Dimethoxyphenethyl)-6-(4-Phenylbutoxy)Hexan-1-Amine (XOB): A Novel Phenylalkylamine Antagonist of Serotonin 2A Receptors and Voltage-Gated Sodium Channels. (Denomme N, Hernandez CC, Bock HA, Ohana RF, Bakshi S, Sherwood AM, McCorvy JD, Daley PF, Callaway WB, Hull JM, Alt A, Isom LL, Cozzi NV) Mol Pharmacol 2024 Jul 17;106(2):92-106 |
| 3 | Mitigating gut microbial degradation of levodopa and enhancing brain dopamine: Implications in Parkinson's disease. (Cheng G, Hardy M, Hillard CJ, Feix JB, Kalyanaraman B) Commun Biol 2024 May 30;7(1):668 1 Citation |
| 2 | Cellular metabolism of substance P produces neurokinin-1 receptor peptide agonists with diminished cyclic AMP signaling. (Kriska T, Natarajan J, Herrnreiter A, Park SK, Pfister SL, Thomas MJ, Widiapradja A, Levick SP, Campbell WB) Am J Physiol Cell Physiol 2024 Jul 01;327(1):C151-C167 |
| 1 | IL-27 promotes pathogenic T cells in a mouse model of Sjögren's disease. (Debreceni IL, Barr JY, Upton EM, Chen YG, Lieberman SM) Clin Immunol 2024 Jul;264:110260 |
| 2 | Gelsolin regulates receptor-mediated and fluid-phase endocytosis in platelets. (Paul M, Hong F, Falet H, Kim H) J Thromb Haemost 2024 Sep;22(9):2601-2607 1 Citation |
| 1 | Low-Temperature Plasma Pretreatment Enhanced Cholesterol Detection in Brain by Desorption Electrospray Ionization-Mass Spectrometry Imaging. (Rahman MM, Islam A, Mamun MA, Afroz MS, Nabi MM, Sakamoto T, Sato T, Kahyo T, Takahashi Y, Okino A, Setou M) J Am Soc Mass Spectrom 2024 Jun 05;35(6):1227-1236 1 Citation |
| 1 | CXCL16-dependent scavenging of oxidized lipids by islet macrophages promotes differentiation of pathogenic CD8+ T cells in diabetic autoimmunity. (Srivastava N, Hu H, Peterson OJ, Vomund AN, Stremska M, Zaman M, Giri S, Li T, Lichti CF, Zakharov PN, Zhang B, Abumrad NA, Chen YG, Ravichandran KS, Unanue ER, Wan X) Immunity 2024 Jul 09;57(7):1629-1647.e8 9 Citations |
| 2 | FOXP4-mediated induction of PTK7 activates the Wnt/β-catenin pathway and promotes ovarian cancer development. (Ji J, Qian Q, Cheng W, Ye X, Jing A, Ma S, Ding Y, Ma X, Wang Y, Sun Q, Wang X, Chen Y, Zhu L, Yuan Q, Xu M, Qin J, Ma L, Yang J, Zhang M, Geng T, Wang S, Wang D, Song Y, Zhang B, Xu Y, Xu L, Liu S, Liu W, Liu B) Cell Death Dis 2024 May 13;15(5):332 5 Citations |
| 2 | Fate control engagement augments NK cell responses in LV/hu-IL-12 transduced sarcoma. (Rademacher MJ, Faber ML, Bone KM, Medin JA, Schloemer NJ) Exp Mol Pathol 2024 Jun;137:104898 1 Citation |
| 1 | Elucidating Gender-Specific Distribution of Imipramine, Chloroquine, and Their Metabolites in Mice Kidney Tissues through AP-MALDI-MSI. (Islam MM, Rahman MF, Islam A, Afroz MS, Mamun MA, Rahman MM, Maniruzzaman M, Xu L, Sakamoto T, Takahashi Y, Sato T, Kahyo T, Setou M) Int J Mol Sci 2024 Apr 29;25(9) 2 Citations |
| 1 | Potential limitations of microdystrophin gene therapy for Duchenne muscular dystrophy. (Hart CC, Lee YI, Xie J, Gao G, Lin BL, Hammers DW, Sweeney HL) JCI Insight 2024 May 07;9(11) 8 Citations |
| 5 | Type 2 cannabinoid receptor expression on microglial cells regulates neuroinflammation during graft-versus-host disease. (Moe A, Rayasam A, Sauber G, Shah RK, Doherty A, Yuan CY, Szabo A, Moore BM 2nd, Colonna M, Cui W, Romero J, Zamora AE, Hillard CJ, Drobyski WR) J Clin Invest 2024 Apr 25;134(11) 3 Citations |
| 1 | CXXC5 drove inflammation and ovarian cancer proliferation via transcriptional activation of ZNF143 and EGR1. (Geng T, Sun Q, He J, Chen Y, Cheng W, Shen J, Liu B, Zhang M, Wang S, Asan K, Song M, Gao Q, Song Y, Liu R, Liu X, Ding Y, Jing A, Ye X, Ren H, Zeng K, Zhou Y, Zhang B, Ma S, Liu W, Liu S, Ji J) Cell Signal 2024 Jul;119:111180 2 Citations |
| 4 | Genetic Deletion of β-Arrestin 2 From the Subfornical Organ and Other Periventricular Nuclei in the Brain Alters Fluid Homeostasis and Blood Pressure. (Mathieu NM, Tan EE, Reho JJ, Brozoski DT, Muskus PC, Lu KT, Wackman KK, Grobe JL, Nakagawa P, Sigmund CD) Hypertension 2024 Jun;81(6):1332-1344 1 Citation |
| 2 | CCR2-dependent CX3CR1+ colonic macrophages promote Enterococcus faecalis dissemination. (Jennings KC, Johnson KE, Hayward MA, Kristich CJ, Salzman NH) Infect Immun 2024 May 07;92(5):e0000624 1 Citation |
| 1 | Recurrent RhoGAP gene fusion CLDN18-ARHGAP26 promotes RHOA activation and focal adhesion kinase and YAP-TEAD signalling in diffuse gastric cancer. (Zhang F, Sahu V, Peng K, Wang Y, Li T, Bala P, Aitymbayev D, Sahgal P, Schaefer A, Der CJ, Ryeom S, Yoon S, Sethi N, Bass AJ, Zhang H) Gut 2024 Jul 11;73(8):1280-1291 6 Citations |
| 4 | Zinc-chelating BET bromodomain inhibitors equally target islet endocrine cell types. (Jones Lipinski RA, Stancill JS, Nuñez R, Wynia-Smith SL, Sprague DJ, Nord JA, Bird A, Corbett JA, Smith BC) Am J Physiol Regul Integr Comp Physiol 2024 Jun 01;326(6):R515-R527 1 Citation |
| 3 | Bhlhe40 Promotes CD4+ T Helper 1 Cell and Suppresses T Follicular Helper Cell Differentiation during Viral Infection. (Nguyen C, Kudek M, Zander R, Niu H, Shen J, Bauer A, Alson D, Khatun A, Chen Y, Sun J, Drobyski W, Edelson BT, Cui W) J Immunol 2024 Jun 01;212(11):1829-1842 1 Citation |
| 1 | Manzamine A reduces androgen receptor transcription and synthesis by blocking E2F8-DNA interactions and effectively inhibits prostate tumor growth in mice. (Karan D, Dubey S, Gunewardena S, Iczkowski KA, Singh M, Liu P, Poletti A, Choo YM, Chen HZ, Hamann MT) Mol Oncol 2024 Aug;18(8):1966-1979 2 Citations |
| 1 | Dermal injury drives a skin to gut axis that disrupts the intestinal microbiome and intestinal immune homeostasis in mice. (Dokoshi T, Chen Y, Cavagnero KJ, Rahman G, Hakim D, Brinton S, Schwarz H, Brown EA, O'Neill A, Nakamura Y, Li F, Salzman NH, Knight R, Gallo RL) Nat Commun 2024 Apr 08;15(1):3009 14 Citations |
| 2 | β-Cell-selective regulation of gene expression by nitric oxide. (Naatz A, Yeo CT, Hogg N, Corbett JA) Am J Physiol Regul Integr Comp Physiol 2024 Jun 01;326(6):R552-R566 1 Citation |
| 1 | Updates to the Alliance of Genome Resources central infrastructure. (Alliance of Genome Resources Consortium
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| 1 | Canonical Wnt activator Chir99021 prevents epileptogenesis in the intrahippocampal kainate mouse model of temporal lobe epilepsy. (Mardones MD, Rostam KD, Nickerson MC, Gupta K) Exp Neurol 2024 Jun;376:114767 3 Citations |
| 1 | An anti-GD2 aptamer-based bifunctional spherical nucleic acid nanoplatform for synergistic therapy targeting MDM2 for retinoblastoma. (Wang S, Zhao Y, Yao F, Wei P, Ma L, Zhang S) Biomed Pharmacother 2024 May;174:116437 2 Citations |
| 1 | Erlotinib combination with a mitochondria-targeted ubiquinone effectively suppresses pancreatic cancer cell survival. (Leung PY, Chen W, Sari AN, Sitaram P, Wu PK, Tsai S, Park JI) World J Gastroenterol 2024 Feb 21;30(7):714-727 3 Citations |
| 1 | Role of the circulating milieu in age-related arterial dysfunction: a novel ex vivo approach. (Mahoney SA, VanDongen NS, Greenberg NT, Venkatasubramanian R, Rossman MJ, Widlansky ME, Brunt VE, Bernaldo de Quirós Y, Seals DR, Clayton ZS) Am J Physiol Heart Circ Physiol 2024 May 01;326(5):H1279-H1290 5 Citations |
| 1 | Large-scale bioreactor production of extracellular vesicles from mesenchymal stromal cells for treatment of acute radiation syndrome. (Kink JA, Bellio MA, Forsberg MH, Lobo A, Thickens AS, Lewis BM, Ong IM, Khan A, Capitini CM, Hematti P) Stem Cell Res Ther 2024 Mar 13;15(1):72 8 Citations |
| 1 | Protocol for the isolation of tumor cell-derived extracellular vesicles followed by in vivo metastasis assessment in a murine ovarian cancer model. (Mittal S, Kumar S, Gupta P, Singh M, Chaluvally-Raghavan P, Pradeep S) STAR Protoc 2024 Jun 21;5(2):102943 |
| 1 | G protein-coupled estrogen receptor (GPER) in the dorsal hippocampus regulates memory consolidation in gonadectomized male mice, likely via different signaling mechanisms than in female mice. (Machado GDB, Schnitzler AL, Fleischer AW, Beamish SB, Frick KM) Horm Behav 2024 May;161:105516 |
| 2 | Lipid nanoparticles and siRNA targeting plasminogen provide lasting inhibition of fibrinolysis in mouse and dog models of hemophilia A. (Strilchuk AW, Hur WS, Batty P, Sang Y, Abrahams SR, Yong ASM, Leung J, Silva LM, Schroeder JA, Nesbitt K, de Laat B, Moutsopoulos NM, Bugge TH, Shi Q, Cullis PR, Merricks EP, Wolberg AS, Flick MJ, Lillicrap D, Nichols TC, Kastrup CJ) Sci Transl Med 2024 Feb 21;16(735):eadh0027 6 Citations |
| 1 | Targeting NUPR1-dependent stress granules formation to induce synthetic lethality in KrasG12D-driven tumors. (Santofimia-Castaño P, Fraunhoffer N, Liu X, Bessone IF, di Magliano MP, Audebert S, Camoin L, Estaras M, Brenière M, Modesti M, Lomberk G, Urrutia R, Soubeyran P, Neira JL, Iovanna J) EMBO Mol Med 2024 Mar;16(3):475-505 5 Citations |
| 5 | Sterile inflammation induces vasculopathy and chronic lung injury in murine sickle cell disease. (Rarick KR, Li K, Teng RJ, Jing X, Martin DP, Xu H, Jones DW, Hogg N, Hillery CA, Garcia G, Day BW, Naylor S, Pritchard KA Jr) Free Radic Biol Med 2024 Mar;215:112-126 4 Citations |
| 1 | DNA hypomethylation ameliorates erosive inflammatory arthritis by modulating interferon regulatory factor-8. (Swarnkar G, Semenkovich NP, Arra M, Mims DK, Naqvi SK, Peterson T, Mbalaviele G, Wu CL, Abu-Amer Y) Proc Natl Acad Sci U S A 2024 Feb 13;121(7):e2310264121 1 Citation |
| 3 | High-speed imaging of evoked rodent mechanical behaviors yields variable results that are not predictive of inflammatory injury. (Rodríguez García DM, Szabo A, Mikesell AR, Zorn SJ, Tsafack UK, Sriram A, Waltz TB, Enders JD, Mecca CM, Stucky CL, Sadler KE) Pain 2024 Jul 01;165(7):1569-1582 3 Citations |
| 4 | Modulatory effects of estrous cycle on ingestive behaviors and energy balance in young adult C57BL/6J mice maintained on a phytoestrogen-free diet. (Reho JJ, Muskus PC, Bennett DM, Grobe CC, Burnett CML, Nakagawa P, Segar JL, Sigmund CD, Grobe JL) Am J Physiol Regul Integr Comp Physiol 2024 Mar 01;326(3):R242-R253 |
| 1 | Red light mediates the exocytosis of vasodilatory vesicles from cultured endothelial cells: a cellular, and ex vivo murine model. (Weihrauch D, Keszler A, Broeckel G, Aranda E, Lindemer B, Lohr NL) Photochem Photobiol Sci 2024 Feb;23(2):355-364 2 Citations |
| 2 | Synaptic and mitochondrial mechanisms behind alcohol-induced imbalance of excitatory/inhibitory synaptic activity and associated cognitive and behavioral abnormalities. (Arzua T, Yan Y, Liu X, Dash RK, Liu QS, Bai X) Transl Psychiatry 2024 Jan 22;14(1):51 2 Citations |
| 1 | Inhibition of Ephrin B2 Reverse Signaling Abolishes Multiple Myeloma Pathogenesis. (Sasine JP, Kozlova NY, Valicente L, Dukov J, Tran DH, Himburg HA, Kumar S, Khorsandi S, Chan A, Grohe S, Li M, Kan J, Sehl ME, Schiller GJ, Reinhardt B, Singh BK, Ho R, Yue P, Pasquale EB, Chute JP) Cancer Res 2024 Mar 15;84(6):919-934 2 Citations |
| 5 | Differences in Fluid, Electrolyte, and Energy Balance in C57BL/6J Mice (Mus musculus) in Metabolic Caging at Thermoneutral or Standard Room Temperatures. (Lawton SB, Grobe CC, Reho JJ, Raff H, Thulin JD, Jensen ES, Burnett CM, Segar JL, Grobe JL) J Am Assoc Lab Anim Sci 2024 Mar 01;63(2):190-200 3 Citations |
| 1 | Kidney Injury by Unilateral Ureteral Obstruction in Mice Lacks Sex Differences. (Goorani S, Khan AH, Mishra A, El-Meanawy A, Imig JD) Kidney Blood Press Res 2024;49(1):69-80 1 Citation |
| 1 | TrkB-mediated sustained neuroprotection is sex-specific and Erα-dependent in adult mice following neonatal hypoxia ischemia. (Chanana V, Hackett M, Deveci N, Aycan N, Ozaydin B, Cagatay NS, Hanalioglu D, Kintner DB, Corcoran K, Yapici S, Camci F, Eickhoff J, Frick KM, Ferrazzano P, Levine JE, Cengiz P) Biol Sex Differ 2024 Jan 04;15(1):1 3 Citations |
| 1 | New Imidazodiazepine Analogue, 5-(8-Bromo-6-(pyridin-2-yl)-4H-benzo[f]imidazo[1,5-a][1,4]diazepin-3-yl)oxazole, Provides a Simplified Synthetic Scheme, High Oral Plasma and Brain Exposures, and Produces Antiseizure Efficacy in Mice, and Antiepileptogenic Activity in Neural Networks in Brain Slices from a Patient with Mesial Temporal Lobe Epilepsy. (Sharmin D, Divović B, Ping X, Cerne R, Smith JL, Rezvanian S, Mondal P, Meyer MJ, Kiley ME, Arnold LA, Mian MY, Pandey KP, Jin X, Mitrović JR, Djorović D, Lippa A, Cook JM, Golani LK, Scholze P, Savić MM, Witkin JM) ACS Chem Neurosci 2024 Feb 07;15(3):517-526 2 Citations |
| 2 | Hyperoxia-induced airflow restriction and Renin-Angiotensin System expression in a bronchopulmonary dysplasia mouse model. (Dowell J, Bice Z, Yan K, Konduri GG) Physiol Rep 2024 Jan;12(1):e15895 |
| 6 | Krüppel-like factor 4 in transcriptional control of the three unique isoforms of Agouti-related peptide in mice. (Ritter ML, Wagner VA, Balapattabi K, Opichka MA, Lu KT, Wackman KK, Reho JJ, Keen HL, Kwitek AE, Morselli LL, Geurts AM, Sigmund CD, Grobe JL) Physiol Genomics 2024 Mar 01;56(3):265-275 |
| 1 | Needle biopsy accelerates pro-metastatic changes and systemic dissemination in breast cancer: Implications for mortality by surgery delay. (Kameyama H, Dondapati P, Simmons R, Leslie M, Langenheim JF, Sun Y, Yi M, Rottschaefer A, Pathak R, Nuguri S, Fung KM, Tsaih SW, Chervoneva I, Rui H, Tanaka T) Cell Rep Med 2023 Dec 19;4(12):101330 7 Citations |
| 1 | RHOAL57V drives the development of diffuse gastric cancer through IGF1R-PAK1-YAP1 signaling. (Schaefer A, Hodge RG, Zhang H, Hobbs GA, Dilly J, Huynh MV, Goodwin CM, Zhang F, Diehl JN, Pierobon M, Baldelli E, Javaid S, Guthrie K, Rashid NU, Petricoin EF, Cox AD, Hahn WC, Aguirre AJ, Bass AJ, Der CJ) Sci Signal 2023 Dec 19;16(816):eadg5289 1 Citation |
| 1 | Identification of 5-HT2A receptor signaling pathways associated with psychedelic potential. (Wallach J, Cao AB, Calkins MM, Heim AJ, Lanham JK, Bonniwell EM, Hennessey JJ, Bock HA, Anderson EI, Sherwood AM, Morris H, de Klein R, Klein AK, Cuccurazzu B, Gamrat J, Fannana T, Zauhar R, Halberstadt AL, McCorvy JD) Nat Commun 2023 Dec 15;14(1):8221 37 Citations |
| 1 | Late gene therapy limits the restoration of retinal function in a mouse model of retinitis pigmentosa. (Scalabrino ML, Thapa M, Wang T, Sampath AP, Chen J, Field GD) Nat Commun 2023 Dec 12;14(1):8256 3 Citations |
| 1 | Cationic micelle delivery of a multi-epitope vaccine candidate derived from tumor-associated antigens, causing regression in established CT26 colorectal tumors in mice. (Sabzehei F, Taromchi AH, Ramazani A, Nedaei K, Feizi A, Arsang-Jang S, Danafar H) J Biomed Mater Res A 2024 May;112(5):733-742 3 Citations |
| 1 | Functional profiling of the G protein-coupled receptor C3aR1 reveals ligand-mediated biased agonism. (Rodriguez P, Laskowski LJ, Pallais JP, Bock HA, Cavalco NG, Anderson EI, Calkins MM, Razzoli M, Sham YY, McCorvy JD, Bartolomucci A) J Biol Chem 2024 Jan;300(1):105549 5 Citations |
| 4 | IL-13 promotes functional recovery after myocardial infarction via direct signaling to macrophages. (Alvarez-Argote S, Paddock SJ, Flinn MA, Moreno CW, Knas MC, Almeida VA, Buday SL, Bakhshian Nik A, Patterson M, Chen YG, Lin CW, O'Meara CC) JCI Insight 2024 Jan 23;9(2) 6 Citations |
| 4 | Interleukin-9 production by type 2 innate lymphoid cells induces Paneth cell metaplasia and small intestinal remodeling. (Yuan C, Rayasam A, Moe A, Hayward M, Wells C, Szabo A, Mackenzie A, Salzman N, Drobyski WR) Nat Commun 2023 Dec 02;14(1):7963 8 Citations |
| 3 | Mitochondrial-targeted antioxidant attenuates preeclampsia-like phenotypes induced by syncytiotrophoblast-specific Gαq signaling. (Opichka MA, Livergood MC, Balapattabi K, Ritter ML, Brozoski DT, Wackman KK, Lu KT, Kozak KN, Wells C, Fogo AB, Gibson-Corley KN, Kwitek AE, Sigmund CD, McIntosh JJ, Grobe JL) Sci Adv 2023 Dec;9(48):eadg8118 5 Citations |
| 1 | Deletion of Vβ3+CD4+ T cells by endogenous mouse mammary tumor virus 3 prevents type 1 diabetes induction by autoreactive CD8+ T cells. (Ye C, Clements SA, Gu W, Geurts AM, Mathews CE, Serreze DV, Chen YG, Driver JP) Proc Natl Acad Sci U S A 2023 Dec 05;120(49):e2312039120 3 Citations |
| 1 | Microglia/macrophages are ultrastructurally altered by their proximity to spinal cord injury in adult female mice. (St-Pierre MK, González Ibáñez F, Kroner A, Tremblay MÈ) J Neuroinflammation 2023 Nov 21;20(1):273 7 Citations |
| 1 | Subclinical respiratory dysfunction and impaired ventilatory adaptation in degenerative cervical myelopathy. (Sweetman H, Rahman M, Vedantam A, Satkunendrarajah K) Exp Neurol 2024 Jan;371:114600 |
| 1 | BCMA- and CST6-specific CAR T cells lyse multiple myeloma cells and suppress murine osteolytic lesions. (Sun F, Cheng Y, Chen JR, Wanchai V, Mery DE, Xu H, Gai D, Al Hadidi S, Schinke C, Thanendrarajan S, Zangari M, van Rhee F, Tricot G, Shaughnessy JD Jr, Zhan F) J Clin Invest 2024 Jan 02;134(1) |
| 3 | A spatial sequencing atlas of age-induced changes in the lung during influenza infection. (Kasmani MY, Topchyan P, Brown AK, Brown RJ, Wu X, Chen Y, Khatun A, Alson D, Wu Y, Burns R, Lin CW, Kudek MR, Sun J, Cui W) Nat Commun 2023 Oct 18;14(1):6597 12 Citations |
| 1 | Sex differences in a murine model of asthma are time and tissue compartment dependent. (Chiarella SE, Cuervo-Pardo L, Coden ME, Jeong BM, Doan TC, Connelly AR, Rodriguez RI, Queener AM, Berdnikovs S) PLoS One 2023;18(10):e0271281 2 Citations |
| 1 | Intravitreal injection of a rationally designed AAV capsid library in non-human primate identifies variants with enhanced retinal transduction and neutralizing antibody evasion. (Kellish PC, Marsic D, Crosson SM, Choudhury S, Scalabrino ML, Strang CE, Hill J, McCullough KT, Peterson JJ, Fajardo D, Gupte S, Makal V, Kondratov O, Kondratova L, Iyer S, Witherspoon CD, Gamlin PD, Zolotukhin S, Boye SL, Boye SE) Mol Ther 2023 Dec 06;31(12):3441-3456 6 Citations |
| 1 | Single-cell mapping identifies MSI+ cells as a common origin for diverse subtypes of pancreatic cancer. (Rajbhandari N, Hamilton M, Quintero CM, Ferguson LP, Fox R, Schürch CM, Wang J, Nakamura M, Lytle NK, McDermott M, Diaz E, Pettit H, Kritzik M, Han H, Cridebring D, Wen KW, Tsai S, Goggins MG, Lowy AM, Wechsler-Reya RJ, Von Hoff DD, Newman AM, Reya T) Cancer Cell 2023 Nov 13;41(11):1989-2005.e9 6 Citations |
| 1 | High NEK2 expression in myeloid progenitors suppresses T cell immunity in multiple myeloma. (Cheng Y, Sun F, Alapat DV, Wanchai V, Mery D, Guo W, Cao H, Zhu Y, Ashby C, Bauer MA, Nookaew I, Siegel ER, Ying J, Chen JR, Gai D, Peng B, Xu H, Bailey C, Al Hadidi S, Schinke C, Thanendrarajan S, Zangari M, Chesi M, Bergsagel PL, van Rhee F, Janz S, Tricot G, Shaughnessy JD Jr, Zhan F) Cell Rep Med 2023 Oct 17;4(10):101214 11 Citations |
| 1 | Psilocybin analog 4-OH-DiPT enhances fear extinction and GABAergic inhibition of principal neurons in the basolateral amygdala. (Kelly TJ, Bonniwell EM, Mu L, Liu X, Hu Y, Friedman V, Yu H, Su W, McCorvy JD, Liu QS) Neuropsychopharmacology 2024 Apr;49(5):854-863 10 Citations |
| 1 | Development and validation of an LC-MS/MS method for the determination of ARN14988, an acid ceramidase inhibitor, and its application to a pharmacokinetic study in a mouse model. (Rajaratnam V, Islam MM, Kub EF, Rajaratnam S, Kim KB, Rahman MT, Rashid F, Benko AM, Cook JM, Arnold LA, Mirza SP) Biomed Chromatogr 2024 Jan;38(1):e5754 |
| 3 | OXPHOS-targeting drugs in oncology: new perspectives. (Kalyanaraman B, Cheng G, Hardy M, You M) Expert Opin Ther Targets 2023;27(10):939-952 19 Citations |
| 1 | Integration of Genomic Sequencing Drives Therapeutic Targeting of PDGFRA in T-Cell Acute Lymphoblastic Leukemia/Lymphoblastic Lymphoma. (Paolino J, Dimitrov B, Apsel Winger B, Sandoval-Perez A, Rangarajan AV, Ocasio-Martinez N, Tsai HK, Li Y, Robichaud AL, Khalid D, Hatton C, Gillani R, Polonen P, Dilig A, Gotti G, Kavanagh J, Adhav AA, Gow S, Tsai J, Li Y, Ebert BL, Van Allen EM, Bledsoe J, Kim AS, Tasian SK, Cooper SL, Cooper TM, Hijiya N, Sulis ML, Shukla NN, Magee JA, Mullighan CG, Burke MJ, Luskin MR, Mar BG, Jacobson MP, Harris MH, Stegmaier K, Place AE, Pikman Y) Clin Cancer Res 2023 Nov 14;29(22):4613-4626 3 Citations |
| 5 | Early-life sodium deprivation programs long-term changes in ingestive behaviors and energy expenditure in C57BL/6J mice. (Ziegler AA, Lawton SBR, Grobe CC, Reho JJ, Freudinger BP, Burnett CML, Nakagawa P, Grobe JL, Segar JL) Am J Physiol Regul Integr Comp Physiol 2023 Nov 01;325(5):R576-R592 3 Citations |
| 1 | An essential signaling function of cytoplasmic NELFB is independent of RNA polymerase II pausing. (Pan H, Cheng X, Rodríguez PFG, Zhang X, Chung I, Jin VX, Li W, Hu Y, Li R) J Biol Chem 2023 Nov;299(11):105259 |
| 2 | PACSIN2 regulates platelet integrin β1 hemostatic function. (Biswas R, Boyd EK, Eaton N, Steenackers A, Schulte ML, Reusswig F, Yu H, Drew C, Kahr WHA, Shi Q, Plomann M, Hoffmeister KM, Falet H) J Thromb Haemost 2023 Dec;21(12):3619-3632 |
| 1 | MiR-9-1 controls osteoblastic regulation of lymphopoiesis. (Zhang Y, Lin D, Zheng Y, Chen Y, Yu M, Cui D, Huang M, Su X, Sun Y, Chen Y, Qian Z, Carlson KS, Wen R, Wang D) Leukemia 2023 Nov;37(11):2261-2275 3 Citations |
| 3 | Intracellular tPA-PAI-1 interaction determines VLDL assembly in hepatocytes. (Dai W, Zhang H, Lund H, Zhang Z, Castleberry M, Rodriguez M, Kuriakose G, Gupta S, Lewandowska M, Powers HR, Valmiki S, Zhu J, Shapiro AD, Hussain MM, López JA, Sorci-Thomas MG, Silverstein RL, Ginsberg HN, Sahoo D, Tabas I, Zheng Z) Science 2023 Sep;381(6661):eadh5207 19 Citations |
| 1 | CUX1-related neurodevelopmental disorder: deep insights into phenotype-genotype spectrum and underlying pathology. (Oppermann H, Marcos-Grañeda E, Weiss LA, Gurnett CA, Jelsig AM, Vineke SH, Isidor B, Mercier S, Magnussen K, Zacher P, Hashim M, Pagnamenta AT, Race S, Srivastava S, Frazier Z, Maiwald R, Pergande M, Milani D, Rinelli M, Levy J, Krey I, Fontana P, Lonardo F, Riley S, Kretzer J, Rankin J, Reis LM, Semina EV, Reuter MS, Scherer SW, Iascone M, Weis D, Fagerberg CR, Brasch-Andersen C, Hansen LK, Kuechler A, Noble N, Gardham A, Tenney J, Rathore G, Beck-Woedl S, Haack TB, Pavlidou DC, Atallah I, Vodopiutz J, Janecke AR, Hsieh TC, Lesmann H, Klinkhammer H, Krawitz PM, Lemke JR, Jamra RA, Nieto M, Tümer Z, Platzer K) Eur J Hum Genet 2023 Nov;31(11):1251-1260 5 Citations |
| 1 | Novel anti-CD30/CD3 bispecific antibodies activate human T cells and mediate potent anti-tumor activity. (Faber ML, Oldham RAA, Thakur A, Rademacher MJ, Kubicka E, Dlugi TA, Gifford SA, McKillop WM, Schloemer NJ, Lum LG, Medin JA) Front Immunol 2023;14:1225610 7 Citations |
| 1 | A fetal wound healing program after intrauterine bile duct injury may contribute to biliary atresia. (de Jong IEM, Hunt ML, Chen D, Du Y, Llewellyn J, Gupta K, Li D, Erxleben D, Rivas F, Hall AR, Furth EE, Naji A, Liu C, Dhand A, Burdick JA, Davey MG, Flake AW, Porte RJ, Russo PA, Gaynor JW, Wells RG) J Hepatol 2023 Dec;79(6):1396-1407 11 Citations |
| 5 | Genetic Ablation of Prorenin Receptor in the Rostral Ventrolateral Medulla Influences Blood Pressure and Hydromineral Balance in Deoxycorticosterone-Salt Hypertension. (Mathieu NM, Fekete EM, Muskus PC, Brozoski DT, Lu KT, Wackman KK, Gomez J, Fang S, Reho JJ, Grobe CC, Vazirabad I, Mouradian GC Jr, Hodges MR, Segar JL, Grobe JL, Sigmund CD, Nakagawa P) Function (Oxf) 2023;4(5):zqad043 3 Citations |
| 1 | Increased liver stiffness promotes hepatitis B progression by impairing innate immunity in CCl4-induced fibrotic HBV+ transgenic mice. (Bybee G, Moeun Y, Wang W, Kharbanda KK, Poluektova LY, Kidambi S, Osna NA, Ganesan M) Front Immunol 2023;14:1166171 5 Citations |
| 3 | BATF is Required for Treg Homeostasis and Stability to Prevent Autoimmune Pathology. (Khatun A, Wu X, Qi F, Gai K, Kharel A, Kudek MR, Fraser L, Ceicko A, Kasmani MY, Majnik A, Burns R, Chen YG, Salzman N, Taparowsky EJ, Fang D, Williams CB, Cui W) Adv Sci (Weinh) 2023 Oct;10(28):e2206692 9 Citations |
| 1 | High-density lipoprotein regulates angiogenesis by long non-coding RNA HDRACA. (Mo ZW, Peng YM, Zhang YX, Li Y, Kang BA, Chen YT, Li L, Sorci-Thomas MG, Lin YJ, Cao Y, Chen S, Liu ZL, Gao JJ, Huang ZP, Zhou JG, Wang M, Chang GQ, Deng MJ, Liu YJ, Ma ZS, Hu ZJ, Dong YG, Ou ZJ, Ou JS) Signal Transduct Target Ther 2023 Aug 14;8(1):299 11 Citations |
| 1 | Lipid Polyunsaturated Fatty Acid Chains in Mouse Kidneys Were Increased within 5 min of a Single High Dose Whole Body Irradiation. (Li W, Zhang C, Aramaki S, Xu L, Tsuge S, Sakamoto T, Mamun MA, Islam A, Hayakawa T, Takanashi Y, Dubail M, Konishi K, Sato T, Kahyo T, Fouillade C, Nakamura K, Setou M) Int J Mol Sci 2023 Aug 04;24(15) 3 Citations |
| 3 | Synthesis of fluorinated triphenylphosphonium analogs that improve cancer cell selectivity and in vivo detection. (Keyes RF, McAllister D, Dwinell MB, Smith BC) STAR Protoc 2023 Sep 15;4(3):102437 |
| 5 | Angiotensin AT1A receptor signal switching in Agouti-related peptide neurons mediates metabolic rate adaptation during obesity. (Balapattabi K, Yavuz Y, Jiang J, Deng G, Mathieu NM, Ritter ML, Opichka MA, Reho JJ, McCorvy JD, Nakagawa P, Morselli LL, Mouradian GC Jr, Atasoy D, Cui H, Hodges MR, Sigmund CD, Grobe JL) Cell Rep 2023 Aug 29;42(8):112935 6 Citations |
| 1 | Validated graft-specific biomarkers identify patients at risk for chronic graft-versus-host disease and death. (Logan BR, Fu D, Howard A, Fei M, Kou J, Little MR, Adom D, Mohamed FA, Blazar BR, Gafken PR, Paczesny S) J Clin Invest 2023 Aug 01;133(15) 4 Citations |
| 1 | Δ9 -Tetrahydrocannabinol self-administration induces cell type-specific adaptations in the nucleus accumbens core. (Garcia-Keller C, Hohmeister M, Seidling K, Beloate L, Chioma V, Spencer S, Kalivas P, Neuhofer D) Addict Biol 2023 Aug;28(8):e13286 2 Citations |
| 6 | Cardiometabolic Effects of DOCA-Salt in Mice Depend on Ambient Temperature. (Grobe CC, Reho JJ, Brown-Williams D, Ziegler AA, Mathieu NM, Lawton SBR, Fekete EM, Brozoski DT, Wackman KK, Burnett CML, Nakagawa P, Sigmund CD, Segar JL, Grobe JL) Hypertension 2023 Sep;80(9):1871-1880 1 Citation |
| 2 | A mass spectrometry assay for detection of endogenous and lentiviral engineered hemoglobin in cultured cells and sickle cell disease mice. (Wang X, McKillop WM, Dlugi TA, Faber ML, Alvarez-Argote J, Chambers CB, Wilber A, Medin JA) J Gene Med 2024 Jan;26(1):e3567 |
| 1 | Changes in environmental stress over COVID-19 pandemic likely contributed to failure to replicate adiposity phenotype associated with Krtcap3. (Szalanczy AM, Giorgio G, Goff E, Seshie O, Grzybowski M, Klotz J, Geurts AM, Redei EE, Solberg Woods LC) Physiol Genomics 2023 Oct 01;55(10):452-467 2 Citations |
| 5 | IL6Myc mouse is an immunocompetent model for the development of aggressive multiple myeloma. (Pisano MD, Sun F, Cheng Y, Parashar D, Zhou V, Jing X, Sompallae R, Abrudan J, Zimmermann MT, Mathison A, Janz S, Pufall MA) Haematologica 2023 Dec 01;108(12):3372-3383 2 Citations |
| 1 | Aberrations in Energetic Metabolism and Stress-Related Pathways Contribute to Pathophysiology in the Neb Conditional Knockout Mouse Model of Nemaline Myopathy. (Slick RA, Tinklenberg JA, Sutton J, Zhang L, Meng H, Beatka MJ, Vanden Avond M, Prom MJ, Ott E, Montanaro F, Heisner J, Toro R, Granzier H, Geurts AM, Stowe DF, Hill RB, Lawlor MW) Am J Pathol 2023 Oct;193(10):1528-1547 4 Citations |
| 1 | Different Mouse Models of Nemaline Myopathy Harboring Acta1 Mutations Display Differing Abnormalities Related to Mitochondrial Biology. (Tinklenberg JA, Slick RA, Sutton J, Zhang L, Meng H, Beatka MJ, Vanden Avond M, Prom MJ, Ott E, Montanaro F, Heisner J, Toro R, Hardeman EC, Geurts AM, Stowe DF, Hill RB, Lawlor MW) Am J Pathol 2023 Oct;193(10):1548-1567 3 Citations |
| 1 | Design, Synthesis, and Biological Evaluation of Novel Spiro Imidazobenzodiazepines to Identify Improved Inhaled Bronchodilators. (Webb DA, Meyer MJ, Medubi KM, Tylek AS, Yocum GT, Roni MSR, Zahn NM, Swartwout SA, Masoud AK, Emala CW, Stafford DC, Arnold LA) J Med Chem 2023 Jul 27;66(14):9853-9865 4 Citations |
| 1 | Potent and uniform fetal hemoglobin induction via base editing. (Mayuranathan T, Newby GA, Feng R, Yao Y, Mayberry KD, Lazzarotto CR, Li Y, Levine RM, Nimmagadda N, Dempsey E, Kang G, Porter SN, Doerfler PA, Zhang J, Jang Y, Chen J, Bell HW, Crossley M, Bhoopalan SV, Sharma A, Tisdale JF, Pruett-Miller SM, Cheng Y, Tsai SQ, Liu DR, Weiss MJ, Yen JS) Nat Genet 2023 Jul;55(7):1210-1220 33 Citations |
| 1 | Independent endothelial functions of PIEZO1 and TRPV4 in hepatic portal vein and predominance of PIEZO1 in mechanical and osmotic stress. (Endesh N, Chuntharpursat-Bon E, Revill C, Yuldasheva NY, Futers TS, Parsonage G, Humphreys N, Adamson A, Morley LC, Cubbon RM, Prasad KR, Foster R, Lichtenstein L, Beech DJ) Liver Int 2023 Sep;43(9):2026-2038 15 Citations |
| 1 | Identification of cell division cycle protein 20 in various forms of acute and chronic kidney injury in mice. (Swanson M, Yun J, Collier DM, Seif C, Yang CY, Regner KR, Park F) Am J Physiol Renal Physiol 2023 Aug 01;325(2):F248-F261 |
| 1 | An improved reporter identifies ruxolitinib as a potent and cardioprotective CaMKII inhibitor. (Reyes Gaido OE, Pavlaki N, Granger JM, Mesubi OO, Liu B, Lin BL, Long A, Walker D, Mayourian J, Schole KL, Terrillion CE, Nkashama LJ, Hulsurkar MM, Dorn LE, Ferrero KM, Huganir RL, Müller FU, Wehrens XHT, Liu JO, Luczak ED, Bezzerides VJ, Anderson ME) Sci Transl Med 2023 Jun 21;15(701):eabq7839 23 Citations |
| 3 | Loss of PBAF promotes expansion and effector differentiation of CD8+ T cells during chronic viral infection and cancer. (Kharel A, Shen J, Brown R, Chen Y, Nguyen C, Alson D, Bluemn T, Fan J, Gai K, Zhang B, Kudek M, Zhu N, Cui W) Cell Rep 2023 Jun 27;42(6):112649 10 Citations |
| 2 | Optogenetic urothelial cell stimulation induces bladder contractions and pelvic nerve afferent firing. (Robilotto GL, Yang OJ, Alom F, Johnson RD, Mickle AD) Am J Physiol Renal Physiol 2023 Aug 01;325(2):F150-F163 8 Citations |
| 1 | The Potency of Cowpea Mosaic Virus Particles for Cancer In Situ Vaccination Is Unaffected by the Specific Encapsidated Viral RNA. (Jung E, Chung YH, Mao C, Fiering SN, Steinmetz NF) Mol Pharm 2023 Jul 03;20(7):3589-3597 2 Citations |
| 1 | Identification of Virulence Factors Involved in a Murine Model of Severe Achromobacter xylosoxidans Infection. (Wills BM, Garai P, Riegert MO, Sanchez FT, Pickrum AM, Frank DW, Brockman KL) Infect Immun 2023 Jul 18;91(7):e0003723 3 Citations |
| 1 | A Novel Autologous CAR-T Therapy, YTB323, with Preserved T-cell Stemness Shows Enhanced CAR T-cell Efficacy in Preclinical and Early Clinical Development. (Dickinson MJ, Barba P, Jäger U, Shah NN, Blaise D, Briones J, Shune L, Boissel N, Bondanza A, Mariconti L, Marchal AL, Quinn DS, Yang J, Price A, Sohoni A, Treanor LM, Orlando EJ, Mataraza J, Davis J, Lu D, Zhu X, Engels B, Moutouh-de Parseval L, Brogdon JL, Moschetta M, Flinn IW) Cancer Discov 2023 Sep 06;13(9):1982-1997 70 Citations |
| 3 | Tuft cells mediate commensal remodeling of the small intestinal antimicrobial landscape. (Fung C, Fraser LM, Barrón GM, Gologorsky MB, Atkinson SN, Gerrick ER, Hayward M, Ziegelbauer J, Li JA, Nico KF, Tyner MDW, DeSchepper LB, Pan A, Salzman NH, Howitt MR) Proc Natl Acad Sci U S A 2023 Jun 06;120(23):e2216908120 18 Citations |
| 4 | Spinal muscular atrophy-like phenotype in a mouse model of acid ceramidase deficiency. (Nagree MS, Rybova J, Kleynerman A, Ahrenhoerster CJ, Saville JT, Xu T, Bachochin M, McKillop WM, Lawlor MW, Pshezhetsky AV, Isaeva O, Budde MD, Fuller M, Medin JA) Commun Biol 2023 May 25;6(1):560 8 Citations |
| 1 | Nitric oxide synthase and reduced arterial tone contribute to arteriovenous malformation. (Huang L, Cheng F, Zhang X, Zielonka J, Nystoriak MA, Xiang W, Raygor K, Wang S, Lakshmanan A, Jiang W, Yuan S, Hou KS, Zhang J, Wang X, Syed AU, Juric M, Takahashi T, Navedo MF, Wang RA) Sci Adv 2023 May 26;9(21):eade7280 3 Citations |
| 1 | From bugs to drugs: Bacterial 3-IAA enhances efficacy of chemotherapy in pancreatic cancer. (Seo YD, Wargo JA) Cell Rep Med 2023 May 16;4(5):101039 5 Citations |
| 1 | Resilience to autosomal dominant Alzheimer's disease in a Reelin-COLBOS heterozygous man. (Lopera F, Marino C, Chandrahas AS, O'Hare M, Villalba-Moreno ND, Aguillon D, Baena A, Sanchez JS, Vila-Castelar C, Ramirez Gomez L, Chmielewska N, Oliveira GM, Littau JL, Hartmann K, Park K, Krasemann S, Glatzel M, Schoemaker D, Gonzalez-Buendia L, Delgado-Tirado S, Arevalo-Alquichire S, Saez-Torres KL, Amarnani D, Kim LA, Mazzarino RC, Gordon H, Bocanegra Y, Villegas A, Gai X, Bootwalla M, Ji J, Shen L, Kosik KS, Su Y, Chen Y, Schultz A, Sperling RA, Johnson K, Reiman EM, Sepulveda-Falla D, Arboleda-Velasquez JF, Quiroz YT) Nat Med 2023 May;29(5):1243-1252 76 Citations |
| 1 | Self-delivering mRNA inhibitors of MK2 improve outcomes after spinal cord injury. (Page JJ, Almanza JR, Xiong S, Aishwarya V, Kroner A) J Neuroimmunol 2023 Jun 15;379:578103 1 Citation |
| 1 | Improving retinal vascular endothelial cell tropism through rational rAAV capsid design. (Periasamy R, Patel DD, Boye SL, Boye SE, Lipinski DM) PLoS One 2023;18(5):e0285370 1 Citation |
| 1 | Nedd4-2 up-regulation is associated with ACE2 ubiquitination in hypertension. (Mohammed M, Ogunlade B, Elgazzaz M, Berdasco C, Lakkappa N, Ghita I, Guidry JJ, Sriramula S, Xu J, Restivo L, Mendiola Plá MA, Bowles DE, Beyer AM, Yue X, Lazartigues E, Filipeanu CM) Cardiovasc Res 2023 Sep 05;119(11):2130-2141 21 Citations |
| 3 | Antiproliferative effects of mitochondria-targeted N-acetylcysteine and analogs in cancer cells. (Cheng G, Hardy M, Kalyanaraman B) Sci Rep 2023 May 04;13(1):7254 3 Citations |
| 1 | Cadmium exposure induces a sex-dependent decline in left ventricular cardiac function. (Fitch ML, Kabir R, Ebenebe OV, Taube N, Garbus H, Sinha P, Wang N, Mishra S, Lin BL, Muller GK, Kohr MJ) Life Sci 2023 Jul 01;324:121712 9 Citations |
| 2 | The Protease Inhibitor Amprenavir Protects against Pepsin-Induced Esophageal Epithelial Barrier Disruption and Cancer-Associated Changes. (Blaine-Sauer S, Samuels TL, Yan K, Johnston N) Int J Mol Sci 2023 Apr 05;24(7) 10 Citations |
| 1 | Tumor progression is independent of tumor-associated macrophages in cell lineage-based mouse models of glioblastoma. (Chipman ME, Wang Z, Sun D, Pedraza AM, Bale TA, Parada LF) Proc Natl Acad Sci U S A 2023 Apr 18;120(16):e2222084120 6 Citations |
| 2 | Sulfenylation links oxidative stress to protein disulfide isomerase oxidase activity and thrombus formation. (Yang M, Chiu J, Scartelli C, Ponzar N, Patel S, Patel A, Ferreira RB, Keyes RF, Carroll KS, Pozzi N, Hogg PJ, Smith BC, Flaumenhaft R) J Thromb Haemost 2023 Aug;21(8):2137-2150 9 Citations |
| 1 | Trajectory reconstruction identifies dysregulation of perinatal maturation programs in pluripotent stem cell-derived cardiomyocytes. (Kannan S, Miyamoto M, Zhu R, Lynott M, Guo J, Chen EZ, Colas AR, Lin BL, Kwon C) Cell Rep 2023 Apr 25;42(4):112330 5 Citations |
| 1 | Distinct subpopulations of D1 medium spiny neurons exhibit unique transcriptional responsiveness to cocaine. (Phillips RA 3rd, Tuscher JJ, Fitzgerald ND, Wan E, Zipperly ME, Duke CG, Ianov L, Day JJ) Mol Cell Neurosci 2023 Jun;125:103849 17 Citations |
| 1 | Inflammatory CD4/CD8 double-positive human T cells arise from reactive CD8 T cells and are sufficient to mediate GVHD pathology. (Hess NJ, Turicek DP, Riendeau J, McIlwain SJ, Contreras Guzman E, Nadiminti K, Hudson A, Callander NS, Skala MC, Gumperz JE, Hematti P, Capitini CM) Sci Adv 2023 Mar 24;9(12):eadf0567 17 Citations |
| 1 | Epidermal Growth Factor Receptor in Hepatic Endothelial Cells Suppresses MCP-1-Dependent Monocyte Recruitment in Diabetes. (Zhang X, Ohayon-Steckel L, Coppin E, Johny E, Dasari A, Florentin J, Vasamsetti S, Dutta P) J Immunol 2023 May 01;210(9):1363-1371 1 Citation |
| 7 | 2022 updates to the Rat Genome Database: a Findable, Accessible, Interoperable, and Reusable (FAIR) resource. (Vedi M, Smith JR, Thomas Hayman G, Tutaj M, Brodie KC, De Pons JL, Demos WM, Gibson AC, Kaldunski ML, Lamers L, Laulederkind SJF, Thota J, Thorat K, Tutaj MA, Wang SJ, Zacher S, Dwinell MR, Kwitek AE) Genetics 2023 May 04;224(1) 23 Citations |
| 2 | Lymphocytic Choriomeningitis Virus Clone 13 Infection Results in CD8 T Cell-Mediated Host Mortality in Diacylglycerol Kinase α-Deficient Mice. (Kudek MR, Xin G, Alson D, Holzhauer S, Shen J, Kasmani MY, Riese M, Cui W) J Immunol 2023 May 01;210(9):1281-1291 |
| 2 | Cardiomyocyte ploidy is dynamic during postnatal development and varies across genetic backgrounds. (Swift SK, Purdy AL, Kolell ME, Andresen KG, Lahue C, Buddell T, Akins KA, Rau CD, O'Meara CC, Patterson M) Development 2023 Apr 01;150(7) 23 Citations |
| 1 | Non-Nutritive Sweeteners Acesulfame Potassium and Sucralose Are Competitive Inhibitors of the Human P-glycoprotein/Multidrug Resistance Protein 1 (PGP/MDR1). (Danner L, Malard F, Valdes R, Olivier-Van Stichelen S) Nutrients 2023 Feb 23;15(5) 4 Citations |
| 1 | Peripheral transient receptor potential vanilloid type 4 hypersensitivity contributes to chronic sickle cell disease pain. (Ehlers VL, Sadler KE, Stucky CL) Pain 2023 Aug 01;164(8):1874-1886 5 Citations |
| 1 | A non-hallucinogenic LSD analog with therapeutic potential for mood disorders. (Lewis V, Bonniwell EM, Lanham JK, Ghaffari A, Sheshbaradaran H, Cao AB, Calkins MM, Bautista-Carro MA, Arsenault E, Telfer A, Taghavi-Abkuh FF, Malcolm NJ, El Sayegh F, Abizaid A, Schmid Y, Morton K, Halberstadt AL, Aguilar-Valles A, McCorvy JD) Cell Rep 2023 Mar 28;42(3):112203 55 Citations |
| 3 | A modified ELISA assay differentiates CCL20 locked dimers from wild-type monomers. (Wu X, Clarke WR, Koplinski CA, Peterson FC, Dwinell MB, Wei G, Chao E, Huynh M, Yamada D, Volkman BF, Hwang ST) J Immunol Methods 2023 Apr;515:113453 |
| 1 | Modeling normal bladder injury after radiation therapy. (Kerns SL, Williams JP, Marples B) Int J Radiat Biol 2023;99(7):1046-1054 1 Citation |
| 2 | Acid Ceramidase Deficiency: Bridging Gaps between Clinical Presentation, Mouse Models, and Future Therapeutic Interventions. (Kleynerman A, Rybova J, Faber ML, McKillop WM, Levade T, Medin JA) Biomolecules 2023 Feb 01;13(2) 12 Citations |
| 1 | Epidermal growth factor receptor inhibition prevents vascular calcifying extracellular vesicle biogenesis. (Bakhshian Nik A, Ng HH, Ashbrook SK, Sun P, Iacoviello F, Shearing PR, Bertazzo S, Mero D, Khomtchouk BB, Hutcheson JD) Am J Physiol Heart Circ Physiol 2023 Apr 01;324(4):H553-H570 12 Citations |
| 1 | TCR-engineered adoptive cell therapy effectively treats intracranial murine glioblastoma. (Schaettler MO, Desai R, Wang AZ, Livingstone AJ, Kobayashi DK, Coxon AT, Bowman-Kirigin JA, Liu CJ, Li M, Bender DE, White MJ, Kranz DM, Johanns TM, Dunn GP) J Immunother Cancer 2023 Feb;11(2) 7 Citations |
| 1 | Psychedelics promote neuroplasticity through the activation of intracellular 5-HT2A receptors. (Vargas MV, Dunlap LE, Dong C, Carter SJ, Tombari RJ, Jami SA, Cameron LP, Patel SD, Hennessey JJ, Saeger HN, McCorvy JD, Gray JA, Tian L, Olson DE) Science 2023 Feb 17;379(6633):700-706 194 Citations |
| 1 | Cord Blood-Derived Endothelial Progenitor Cells Promote In Vivo Regeneration of Human Hematopoietic Bone Marrow. (Doan PL, Frei AC, Piryani SO, Szalewski N, Fan E, Himburg HA) Int J Radiat Oncol Biol Phys 2023 Aug 01;116(5):1163-1174 5 Citations |
| 1 | Endothelial Specific Deletion of Autotaxin Improves Stroke Outcomes. (Bhattarai S, Subedi U, Manikandan S, Sharma S, Sharma P, Miller C, Bhuiyan MS, Kidambi S, Aidinis V, Sun H, Miriyala S, Panchatcharam M) Cells 2023 Feb 03;12(3) 7 Citations |
| 2 | Dual blockage of both PD-L1 and CD47 enhances the therapeutic effect of oxaliplatin and FOLFOX in CT-26 mice tumor model. (Alimohammadi R, Mahmoodi Chalbatani G, Alimohammadi M, Ghaffari-Nazari H, Rahimi A, Mortaz E, Mossafa N, Boon L, Jalali SA) Sci Rep 2023 Feb 11;13(1):2472 10 Citations |
| 1 | Endocannabinoid 2-Arachidonoylglycerol Levels in the Anterior Cingulate Cortex, Caudate Putamen, Nucleus Accumbens, and Piriform Cortex Were Upregulated by Chronic Restraint Stress. (Zhai Q, Islam A, Chen B, Zhang H, Chi DH, Mamun MA, Takahashi Y, Sato N, Yamasue H, Nakajima Y, Nagashima Y, Sano F, Sato T, Kahyo T, Setou M) Cells 2023 Jan 21;12(3) 10 Citations |
| 3 | Heterogeneity of Islet-Infiltrating IL-21+ CD4 T Cells in a Mouse Model of Type 1 Diabetes. (Ciecko AE, Wang Y, Harleston S, Drewek A, Serreze DV, Geurts AM, Lin CW, Chen YG) J Immunol 2023 Apr 01;210(7):935-946 4 Citations |
| 1 | The small GTPase regulatory protein Rac1 drives podocyte injury independent of cationic channel protein TRPC5. (Polat OK, Isaeva E, Sudhini YR, Knott B, Zhu K, Noben M, Suresh Kumar V, Endlich N, Mangos S, Reddy TV, Samelko B, Wei C, Altintas MM, Dryer SE, Sever S, Staruschenko A, Reiser J) Kidney Int 2023 Jun;103(6):1056-1062 10 Citations |
| 1 | Blood tissue Plasminogen Activator (tPA) of liver origin contributes to neurovascular coupling involving brain endothelial N-Methyl-D-Aspartate (NMDA) receptors. (Furon J, Yetim M, Pouettre E, Martinez de Lizarrondo S, Maubert E, Hommet Y, Lebouvier L, Zheng Z, Ali C, Vivien D) Fluids Barriers CNS 2023 Feb 03;20(1):11 4 Citations |
| 1 | Salt-sensitive hypertension after reversal of unilateral ureteral obstruction. (Imig JD, Khan MAH, Stavniichuk A, Jankiewicz WK, Goorani S, Yeboah MM, El-Meanawy A) Biochem Pharmacol 2023 Apr;210:115438 3 Citations |
| 1 | Pre-existing anti-factor VIII immunity alters therapeutic platelet-targeted factor VIII engraftment following busulfan conditioning through cytotoxic CD8 T cells. (Jing W, Baumgartner CK, Xue F, Schroeder JA, Shi Q) J Thromb Haemost 2023 Mar;21(3):488-498 2 Citations |
| 1 | Platelet tissue factor pathway inhibitor-α dampens cardiac thrombosis and associated fibrosis in mice. (Maroney SA, Siebert AE, Martinez ND, Rasmussen M, Peterson JA, Weiler H, Lincoln J, Mast AE) J Thromb Haemost 2023 Mar;21(3):639-651 4 Citations |
| 1 | Smarcd3 is an epigenetic modulator of the metabolic landscape in pancreatic ductal adenocarcinoma. (Ferguson LP, Gatchalian J, McDermott ML, Nakamura M, Chambers K, Rajbhandari N, Lytle NK, Rosenthal SB, Hamilton M, Albini S, Wartenberg M, Zlobec I, Galván JA, Karamitopoulou E, Vavinskaya V, Wascher A, Lowy AM, Schürch CM, Puri PL, Bruneau BG, Hargreaves DC, Reya T) Nat Commun 2023 Jan 18;14(1):292 9 Citations |
| 1 | Dynamics of the gut microbiome, IgA response, and plasma metabolome in the development of pediatric celiac disease. (Girdhar K, Dogru YD, Huang Q, Yang Y, Tolstikov V, Raisingani A, Chrudinova M, Oh J, Kelley K, Ludvigsson JF, Kiebish MA, Palm NW, Ludvigsson J, Altindis E) Microbiome 2023 Jan 13;11(1):9 23 Citations |
| 1 | Interleukin-13 and its receptor are synaptic proteins involved in plasticity and neuroprotection. (Li S, Olde Heuvel F, Rehman R, Aousji O, Froehlich A, Li Z, Jark R, Zhang W, Conquest A, Woelfle S, Schoen M, O Meara CC, Reinhardt RL, Voehringer D, Kassubek J, Ludolph A, Huber-Lang M, Knöll B, Morganti-Kossmann MC, Brockmann MM, Boeckers T, Roselli F) Nat Commun 2023 Jan 13;14(1):200 26 Citations |
| 6 | The splanchnic mesenchyme is the tissue of origin for pancreatic fibroblasts during homeostasis and tumorigenesis. (Han L, Wu Y, Fang K, Sweeney S, Roesner UK, Parrish M, Patel K, Walter T, Piermattei J, Trimboli A, Lefler J, Timmers CD, Yu XZ, Jin VX, Zimmermann MT, Mathison AJ, Urrutia R, Ostrowski MC, Leone G) Nat Commun 2023 Jan 03;14(1):1 46 Citations |
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| 1 | Diverse monogenic subforms of human spermatogenic failure. (Nagirnaja L, Lopes AM, Charng WL, Miller B, Stakaitis R, Golubickaite I, Stendahl A, Luan T, Friedrich C, Mahyari E, Fadial E, Kasak L, Vigh-Conrad K, Oud MS, Xavier MJ, Cheers SR, James ER, Guo J, Jenkins TG, Riera-Escamilla A, Barros A, Carvalho F, Fernandes S, Gonçalves J, Gurnett CA, Jørgensen N, Jezek D, Jungheim ES, Kliesch S, McLachlan RI, Omurtag KR, Pilatz A, Sandlow JI, Smith J, Eisenberg ML, Hotaling JM, Jarvi KA, Punab M, Rajpert-De Meyts E, Carrell DT, Krausz C, Laan M, O'Bryan MK, Schlegel PN, Tüttelmann F, Veltman JA, Almstrup K, Aston KI, Conrad DF) Nat Commun 2022 Dec 26;13(1):7953 34 Citations |
| 2 | The Absence of IL-12Rβ2 Expression on Recipient Nonhematopoietic Cells Diminishes Acute Graft-versus-Host Disease in the Gastrointestinal Tract. (Bastian D, Sui X, Choi HJ, Wu Y, Tian L, Yang K, Liu C, Liu Y, Yu XZ) J Immunol 2023 Feb 15;210(4):486-495 |
| 1 | Impact of CD4 T cells on intratumoral CD8 T-cell exhaustion and responsiveness to PD-1 blockade therapy in mouse brain tumors. (Khan SM, Desai R, Coxon A, Livingstone A, Dunn GP, Petti A, Johanns TM) J Immunother Cancer 2022 Dec;10(12) 18 Citations |
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| 1 | Pharmacological Mechanism of the Non-hallucinogenic 5-HT2A Agonist Ariadne and Analogs. (Cunningham MJ, Bock HA, Serrano IC, Bechand B, Vidyadhara DJ, Bonniwell EM, Lankri D, Duggan P, Nazarova AL, Cao AB, Calkins MM, Khirsariya P, Hwu C, Katritch V, Chandra SS, McCorvy JD, Sames D) ACS Chem Neurosci 2023 Jan 04;14(1):119-135 29 Citations |
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| 1 | CD47-SIRPα axis blockade in NASH promotes necroptotic hepatocyte clearance by liver macrophages and decreases hepatic fibrosis. (Shi H, Wang X, Li F, Gerlach BD, Yurdagul A Jr, Moore MP, Zeldin S, Zhang H, Cai B, Zheng Z, Valenti L, Tabas I) Sci Transl Med 2022 Nov 23;14(672):eabp8309 36 Citations |
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| 1 | G9a Modulates Lipid Metabolism in CD4 T Cells to Regulate Intestinal Inflammation. (Ramos GP, Bamidele AO, Klatt EE, Sagstetter MR, Kurdi AT, Hamdan FH, Kosinsky RL, Gaballa JM, Nair A, Sun Z, Dasari S, Lanza IR, Rozeveld CN, Schott MB, Urrutia G, Westphal MS, Clarkson BD, Howe CL, Marietta EV, Luckey DH, Murray JA, Gonzalez M, Braga Neto MB, Gibbons HR, Smyrk TC, Johnsen S, Lomberk G, Faubion WA) Gastroenterology 2023 Feb;164(2):256-271.e10 18 Citations |
| 1 | Collecting duct renin regulates potassium homeostasis in mice. (Xu C, Chen Y, Ramkumar N, Zou CJ, Sigmund CD, Yang T) Acta Physiol (Oxf) 2023 Jan;237(1):e13899 7 Citations |
| 4 | Cardiometabolic Consequences of Deleting the Regulator of G protein Signaling-2 (Rgs2) From Cells Expressing Agouti-Related Peptide or the ANG (Angiotensin) II Type 1A Receptor in Mice. (Ritter ML, Deng G, Reho JJ, Deng Y, Sapouckey SA, Opichka MA, Balapattabi K, Wackman KK, Brozoski DT, Lu KT, Paradee WJ, Gibson-Corley KN, Cui H, Nakagawa P, Morselli LL, Sigmund CD, Grobe JL) Hypertension 2022 Dec;79(12):2843-2853 1 Citation |
| 2 | T cell-extrinsic IL-1 signaling controls long-term gammaherpesvirus infection by suppressing viral reactivation. (Sylvester PA, Corbett JA, Tarakanova VL) Virology 2022 Nov;576:134-140 2 Citations |
| 1 | Transcriptome Profiling of the Hippocampal Seizure Network Implicates a Role for Wnt Signaling during Epileptogenesis in a Mouse Model of Temporal Lobe Epilepsy. (Mardones MD, Gupta K) Int J Mol Sci 2022 Oct 10;23(19) 7 Citations |
| 1 | αVEGFR2-MICA fusion antibodies enhance immunotherapy effect and synergize with PD-1 blockade. (Pan M, Wang F, Nan L, Yang S, Qi J, Xie J, Shao S, Zou H, Wang M, Sun F, Zhang J) Cancer Immunol Immunother 2023 Apr;72(4):969-984 9 Citations |
| 1 | Identification of amino acid domains of Borrelia burgdorferi P66 that are surface exposed and important for localization, oligomerization, and porin function of the protein. (Curtis MW, Fierros CH, Hahn BL, Surdel MC, Kessler J, Anderson PN, Vandewalle-Capo M, Bonde M, Zhu J, Bergström S, Coburn J) Front Cell Infect Microbiol 2022;12:991689 3 Citations |
| 5 | ARRB2 (β-Arrestin-2) Deficiency Alters Fluid Homeostasis and Blood Pressure Regulation. (Mathieu NM, Nakagawa P, Grobe CC, Reho JJ, Brozoski DT, Lu KT, Wackman KK, Ritter ML, Segar JL, Grobe JL, Sigmund CD) Hypertension 2022 Nov;79(11):2480-2492 13 Citations |
| 2 | Sex differences in training-induced activity of the ubiquitin proteasome system in the dorsal hippocampus and medial prefrontal cortex of male and female mice. (Beamish SB, Gross KS, Anderson MM, Helmstetter FJ, Frick KM) Learn Mem 2022 Sep;29(9):302-311 4 Citations |
| 4 | N-terminal BET bromodomain inhibitors disrupt a BRD4-p65 interaction and reduce inducible nitric oxide synthase transcription in pancreatic β-cells. (Nord JA, Wynia-Smith SL, Gehant AL, Jones Lipinski RA, Naatz A, Rioja I, Prinjha RK, Corbett JA, Smith BC) Front Endocrinol (Lausanne) 2022;13:923925 7 Citations |
| 1 | Bespoke library docking for 5-HT2A receptor agonists with antidepressant activity. (Kaplan AL, Confair DN, Kim K, Barros-Álvarez X, Rodriguiz RM, Yang Y, Kweon OS, Che T, McCorvy JD, Kamber DN, Phelan JP, Martins LC, Pogorelov VM, DiBerto JF, Slocum ST, Huang XP, Kumar JM, Robertson MJ, Panova O, Seven AB, Wetsel AQ, Wetsel WC, Irwin JJ, Skiniotis G, Shoichet BK, Roth BL, Ellman JA) Nature 2022 Oct;610(7932):582-591 139 Citations |
| 1 | The Antagonism between the Murine Gammaherpesvirus Protein Kinase and Global Interferon Regulatory Factor 1 Expression Shapes the Establishment of Chronic Infection. (Jondle CN, Sylvester PA, Schmalzriedt DL, Njoya K, Tarakanova VL) J Virol 2022 Oct 26;96(20):e0126022 2 Citations |
| 1 | Elimination of fibrin polymer formation or crosslinking, but not fibrinogen deficiency, is protective against diet-induced obesity and associated pathologies. (Hur WS, King KC, Patel YN, Nguyen YV, Wei Z, Yang Y, Juang LJ, Leung J, Kastrup CJ, Wolberg AS, Luyendyk JP, Flick MJ) J Thromb Haemost 2022 Dec;20(12):2873-2886 10 Citations |
| 1 | Pharmacological TRPC6 inhibition improves survival and muscle function in mice with Duchenne muscular dystrophy. (Lin BL, Shin JY, Jeffreys WP, Wang N, Lukban CA, Moorer MC, Velarde E, Hanselman OA, Kwon S, Kannan S, Riddle RC, Ward CW, Pullen SS, Filareto A, Kass DA) JCI Insight 2022 Oct 10;7(19) 10 Citations |
| 2 | IL-12p40 promotes secondary damage and functional impairment after spinal cord contusional injury. (Rosas Almanza J, Stehlik KE, Page JJ, Xiong SH, Tabor EG, Aperi B, Patel K, Kodali R, Kurpad S, Budde MD, Tarima S, Swartz K, Kroner A) J Neurosci Res 2022 Dec;100(12):2213-2231 3 Citations |
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| 1 | Group 3 innate lymphoid cells require BATF to regulate gut homeostasis in mice. (Wu X, Khatun A, Kasmani MY, Chen Y, Zheng S, Atkinson S, Nguyen C, Burns R, Taparowsky EJ, Salzman NH, Hand TW, Cui W) J Exp Med 2022 Nov 07;219(11) 14 Citations |
| 1 | Robust cone-mediated signaling persists late into rod photoreceptor degeneration. (Scalabrino ML, Thapa M, Chew LA, Zhang E, Xu J, Sampath AP, Chen J, Field GD) Elife 2022 Aug 30;11 8 Citations |
| 1 | Identification of Novel Retinal Pericyte-Targeting rAAV Vectors Through Directed Evolution. (Patel DD, Marsic D, Periasamy R, Zolotukhin S, Lipinski DM) Transl Vis Sci Technol 2022 Aug 01;11(8):28 3 Citations |
| 1 | Combining ablative radiotherapy and anti CD47 monoclonal antibody improves infiltration of immune cells in tumor microenvironments. (Rostami E, Bakhshandeh M, Ghaffari-Nazari H, Alinezhad M, Alimohammadi M, Alimohammadi R, Mahmoodi Chalbatani G, Hejazi E, Webster TJ, Tavakkol-Afshari J, Jalali SA) PLoS One 2022;17(8):e0273547 5 Citations |
| 1 | Bone marrow mesenchymal stromal cells in a 3D system produce higher concentration of extracellular vesicles (EVs) with increased complexity and enhanced neuronal growth properties. (Jalilian E, Massoumi H, Bigit B, Amin S, Katz EA, Guaiquil VH, Anwar KN, Hematti P, Rosenblatt MI, Djalilian AR) Stem Cell Res Ther 2022 Aug 19;13(1):425 35 Citations |
| 1 | Broad-acting therapeutic effects of miR-29b-chitosan on hypertension and diabetic complications. (Jensen DM, Han P, Mangala LS, Lopez-Berestein G, Sood AK, Liu J, Kriegel AJ, Usa K, Widlansky ME, Liang M) Mol Ther 2022 Nov 02;30(11):3462-3476 12 Citations |
| 1 | T Cell-Specific STAT1 Expression Promotes Lytic Replication and Supports the Establishment of Gammaherpesvirus Latent Reservoir in Splenic B Cells. (Sylvester PA, Jondle CN, Schmalzriedt DL, Dittel BN, Tarakanova VL) mBio 2022 Aug 30;13(4):e0210722 3 Citations |
| 1 | The long and winding road: From mouse linkage studies to a novel human therapeutic pathway in type 1 diabetes. (Rojas M, Heuer LS, Zhang W, Chen YG, Ridgway WM) Front Immunol 2022;13:918837 2 Citations |
| 1 | Heterologous production of the adhesin LIC13411 from pathogenic Leptospira facilitates binding of non-pathogenic Leptospira in vitro and in vivo. (Surdel MC, Hahn BL, Anderson PN, Coburn J) Front Cell Infect Microbiol 2022;12:917963 3 Citations |
| 1 | Hematogenous dissemination of pathogenic and non-pathogenic Leptospira in a short-term murine model of infection. (Surdel MC, Anderson PN, Hahn BL, Coburn J) Front Cell Infect Microbiol 2022;12:917962 8 Citations |
| 2 | rAAV-mediated over-expression of acid ceramidase prevents retinopathy in a mouse model of Farber lipogranulomatosis. (Zhang H, Nagree MS, Liu H, Pan X, Medin JA, Lipinski DM) Gene Ther 2023 Apr;30(3-4):297-308 4 Citations |
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| 1 | Genetically detoxified tetanus toxin as a vaccine and conjugate carrier protein. (Chang MJ, Ollivault-Shiflett M, Schuman R, Ngoc Nguyen S, Kaltashov IA, Bobst C, Rajagopal SP, Przedpelski A, Barbieri JT, Lees A) Vaccine 2022 Aug 19;40(35):5103-5113 7 Citations |
| 2 | Deletion of Thioredoxin Reductase Disrupts Redox Homeostasis and Impairs β-Cell Function. (Stancill JS, Hansen PA, Mathison AJ, Schmidt EE, Corbett JA) Function (Oxf) 2022;3(4):zqac034 16 Citations |
| 1 | APOE4 homozygote females are resistant to the beneficial effects of 17β-estradiol on memory and CA1 dendritic spine density in the EFAD mouse model of Alzheimer's disease. (Taxier LR, Philippi SM, Fleischer AW, York JM, LaDu MJ, Frick KM) Neurobiol Aging 2022 Oct;118:13-24 12 Citations |
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| 1 | Imidazobenzodiazepine PI320 Relaxes Mouse Peripheral Airways by Inhibiting Calcium Mobilization. (Perez-Zoghbi JF, Sajorda DR, Webb DA, Arnold LA, Emala CW, Yocum GT) Am J Respir Cell Mol Biol 2022 Oct;67(4):482-490 4 Citations |
| 2 | Combinatorial genetics reveals the Dock1-Rac2 axis as a potential target for the treatment of NPM1;Cohesin mutated AML. (Meyer AE, Stelloh C, Pulakanti K, Burns R, Fisher JB, Heimbruch KE, Tarima S, Furumo Q, Brennan J, Zheng Y, Viny AD, Vassiliou GS, Rao S) Leukemia 2022 Aug;36(8):2032-2041 6 Citations |
| 1 | T Cell-Intrinsic Interleukin 17 Receptor A Signaling Supports the Establishment of Chronic Murine Gammaherpesvirus 68 Infection. (Jondle CN, Tarakanova VL) J Virol 2022 Jul 27;96(14):e0063922 4 Citations |
| 1 | Anchoring IgG-degrading enzymes to the surface of platelets selectively neutralizes antiplatelet antibodies. (Lynch DR, Stringham EN, Zhang B, Balbin-Cuesta G, Curtis BR, Palumbo JS, Greineder CF, Tourdot BE) Blood Adv 2022 Aug 09;6(15):4645-4656 6 Citations |
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| 1 | Blockade of interleukin 10 potentiates antitumour immune function in human colorectal cancer liver metastases. (Sullivan KM, Jiang X, Guha P, Lausted C, Carter JA, Hsu C, Labadie KP, Kohli K, Kenerson HL, Daniel SK, Yan X, Meng C, Abbasi A, Chan M, Seo YD, Park JO, Crispe IN, Yeung RS, Kim TS, Gujral TS, Tian Q, Katz SC, Pillarisetty VG) Gut 2023 Feb;72(2):325-337 82 Citations |
| 1 | Haploinsufficiency of a Circadian Clock Gene Bmal1 (Arntl or Mop3) Causes Brain-Wide mTOR Hyperactivation and Autism-like Behavioral Phenotypes in Mice. (Singla R, Mishra A, Lin H, Lorsung E, Le N, Tin S, Jin VX, Cao R) Int J Mol Sci 2022 Jun 05;23(11) 13 Citations |
| 4 | Oral and Inhaled Fosamprenavir Reverses Pepsin-Induced Damage in a Laryngopharyngeal Reflux Mouse Model. (Johnston N, Samuels TL, Goetz CJ, Arnold LA, Smith BC, Seabloom D, Wuertz B, Ondrey F, Wiedmann TS, Vuksanovic N, Silvaggi NR, MacKinnon AC, Miller J, Bock J, Blumin JH) Laryngoscope 2023 Jan;133 Suppl 1(Suppl 1):S1-S11 12 Citations |
| 1 | Autoreactive CD8 T cells in NOD mice exhibit phenotypic heterogeneity but restricted TCR gene usage. (Kasmani MY, Ciecko AE, Brown AK, Petrova G, Gorski J, Chen YG, Cui W) Life Sci Alliance 2022 Oct;5(10) 5 Citations |
| 1 | Comparison of DLin-MC3-DMA and ALC-0315 for siRNA Delivery to Hepatocytes and Hepatic Stellate Cells. (Ferraresso F, Strilchuk AW, Juang LJ, Poole LG, Luyendyk JP, Kastrup CJ) Mol Pharm 2022 Jul 04;19(7):2175-2182 55 Citations |
| 1 | VEGF Receptor 1 Promotes Hypoxia-Induced Hematopoietic Progenitor Proliferation and Differentiation. (Florentin J, O'Neil SP, Ohayon LL, Uddin A, Vasamsetti SB, Arunkumar A, Ghosh S, Boatz JC, Sui J, Kliment CR, Chan SY, Dutta P) Front Immunol 2022;13:882484 14 Citations |
| 1 | Human epiblast lumenogenesis: From a cell aggregate to a lumenal cyst. (Carleton AE, Duncan MC, Taniguchi K) Semin Cell Dev Biol 2022 Nov;131:117-123 5 Citations |
| 2 | Sleeve Gastrectomy Improves High-Fat Diet-Associated Hepatic Steatosis Independent of the Glucagon-like-Petpide-1 Receptor in Rats. (Barron M, Hayes H, Fernando DG, Geurts AM, Kindel TL) J Gastrointest Surg 2022 Aug;26(8):1607-1618 1 Citation |
| 1 | Depletion of skeletal muscle satellite cells attenuates pathology in muscular dystrophy. (Boyer JG, Huo J, Han S, Havens JR, Prasad V, Lin BL, Kass DA, Song T, Sadayappan S, Khairallah RJ, Ward CW, Molkentin JD) Nat Commun 2022 May 26;13(1):2940 26 Citations |
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| 2 | Transcriptional Landscape Established by the Euchromatic Histone-lysine N-methyltransferase Pathway During Pancreas Ontogenesis and Pancreatitis. (Urrutia R, Salmonson A, Urrutia G, de Assuncao TM, Zimmermann MT, Mathison AJ, Lomberk G) FASEB J 2022 May;36 Suppl 1 |
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| 1 | Blocking hemophilic arthropathy. (Shi Q, Weiler H) Blood 2022 May 05;139(18):2734-2735 2 Citations |
| 1 | Albumin nanoparticle containing a PI3Kγ inhibitor and paclitaxel in combination with α-PD1 induces tumor remission of breast cancer in mice. (Song Y, Bugada L, Li R, Hu H, Zhang L, Li C, Yuan H, Rajanayake KK, Truchan NA, Wen F, Gao W, Sun D) Sci Transl Med 2022 May 04;14(643):eabl3649 71 Citations |
| 1 | Role of cathepsin K in the expression of mechanical hypersensitivity following intra-plantar inflammation. (Paracha M, Thakar A, Darling RA, Wulff SS, Rule DC, Nair S, Brown TE) Sci Rep 2022 May 02;12(1):7108 |
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| 1 | Ketogenic diet prevents methylglyoxal-evoked nociception by scavenging methylglyoxal. (Enders JD, Thomas S, Swanson MT, Ryals JM, Wright DE) Pain 2022 Dec 01;163(12):e1207-e1216 1 Citation |
| 1 | Variation in blood microbial lipopolysaccharide (LPS) contributes to immune reconstitution in response to suppressive antiretroviral therapy in HIV. (Luo Z, Health SL, Li M, Yang H, Wu Y, Collins M, Deeks SG, Martin JN, Scott A, Jiang W) EBioMedicine 2022 Jun;80:104037 23 Citations |
| 1 | Extracellular matrix metalloproteinase-9 (MMP-9) is required in female mice for 17β-estradiol enhancement of hippocampal memory consolidation. (Gross KS, Lincoln CM, Anderson MM, Geiger GE, Frick KM) Psychoneuroendocrinology 2022 Jul;141:105773 4 Citations |
| 1 | Cannabinoid receptor 1 antagonist genistein attenuates marijuana-induced vascular inflammation. (Wei TT, Chandy M, Nishiga M, Zhang A, Kumar KK, Thomas D, Manhas A, Rhee S, Justesen JM, Chen IY, Wo HT, Khanamiri S, Yang JY, Seidl FJ, Burns NZ, Liu C, Sayed N, Shie JJ, Yeh CF, Yang KC, Lau E, Lynch KL, Rivas M, Kobilka BK, Wu JC) Cell 2022 May 12;185(10):1676-1693.e23 80 Citations |
| 1 | Amygdalar CB2 cannabinoid receptor mediates fear extinction deficits promoted by orexin-A/hypocretin-1. (Ten-Blanco M, Flores Á, Pereda-Pérez I, Piscitelli F, Izquierdo-Luengo C, Cristino L, Romero J, Hillard CJ, Maldonado R, Di Marzo V, Berrendero F) Biomed Pharmacother 2022 May;149:112925 16 Citations |
| 1 | A periplasmic cinched protein is required for siderophore secretion and virulence of Mycobacterium tuberculosis. (Zhang L, Kent JE, Whitaker M, Young DC, Herrmann D, Aleshin AE, Ko YH, Cingolani G, Saad JS, Moody DB, Marassi FM, Ehrt S, Niederweis M) Nat Commun 2022 Apr 26;13(1):2255 17 Citations |
| 5 | Melanocortin MC4R receptor is required for energy expenditure but not blood pressure effects of angiotensin II within the mouse brain. (Oliveira V, Riedl RA, Claflin KE, Mathieu NM, Ritter ML, Balapattabi K, Wackman KK, Reho JJ, Brozoski DT, Morgan DA, Cui H, Rahmouni K, Burnett CML, Nakagawa P, Sigmund CD, Morselli LL, Grobe JL) Physiol Genomics 2022 Jun 01;54(6):196-205 5 Citations |
| 1 | Baicalin regulates autophagy to interfere with small intestinal acute graft-versus-host disease. (Sun X, Pisano M, Xu L, Sun F, Xu J, Zheng W, Liu X, Zhang Y, Sun R, Cui X) Sci Rep 2022 Apr 21;12(1):6551 10 Citations |
| 1 | Human brain sialoglycan ligand for CD33, a microglial inhibitory Siglec implicated in Alzheimer's disease. (Gonzalez-Gil A, Porell RN, Fernandes SM, Maenpaa E, Li TA, Li T, Wong PC, Aoki K, Tiemeyer M, Yu ZJ, Orsburn BC, Bumpus NN, Matthews RT, Schnaar RL) J Biol Chem 2022 Jun;298(6):101960 29 Citations |
| 1 | Radiation dose and schedule influence the abscopal effect in a bilateral murine CT26 tumor model. (Ghaffari-Nazari H, Alimohammadi M, Alimohammadi R, Rostami E, Bakhshandeh M, Webster TJ, Mahmoodi Chalbatani G, Tavakkol-Afshari J, Amir Jalali S) Int Immunopharmacol 2022 Jul;108:108737 14 Citations |
| 1 | Stress upregulates 2-arachidonoylglycerol levels in the hypothalamus, midbrain, and hindbrain, and it is sustained by green nut oil supplementation in SAMP8 mice revealed by DESI-MSI. (Islam A, Takeyama E, Nabi MM, Zhai Q, Fukushima M, Watanabe N, Al Mamun M, Kikushima K, Kahyo T, Setou M) Biochem Biophys Res Commun 2022 Jun 18;609:9-14 9 Citations |
| 1 | Harmonizing model organism data in the Alliance of Genome Resources. (Alliance of Genome Resources Consortium) Genetics 2022 Apr 04;220(4) 21 Citations |
| 8 | MOET: a web-based gene set enrichment tool at the Rat Genome Database for multiontology and multispecies analyses. (Vedi M, Nalabolu HS, Lin CW, Hoffman MJ, Smith JR, Brodie K, De Pons JL, Demos WM, Gibson AC, Hayman GT, Hill ML, Kaldunski ML, Lamers L, Laulederkind SJF, Thorat K, Thota J, Tutaj M, Tutaj MA, Wang SJ, Zacher S, Dwinell MR, Kwitek AE) Genetics 2022 Apr 04;220(4) 8 Citations |
| 1 | Neutrophil extracellular traps regulate ischemic stroke brain injury. (Denorme F, Portier I, Rustad JL, Cody MJ, de Araujo CV, Hoki C, Alexander MD, Grandhi R, Dyer MR, Neal MD, Majersik JJ, Yost CC, Campbell RA) J Clin Invest 2022 May 16;132(10) 188 Citations |
| 6 | RhoBTB1 reverses established arterial stiffness in angiotensin II-induced hypertension by promoting actin depolymerization. (Fang S, Wu J, Reho JJ, Lu KT, Brozoski DT, Kumar G, Werthman AM, Silva SD Jr, Muskus Veitia PC, Wackman KK, Mathison AJ, Teng BQ, Lin CW, Quelle FW, Sigmund CD) JCI Insight 2022 May 09;7(9) 12 Citations |
| 1 | A Long-Term Study Evaluating the Effects of Nicorandil Treatment on Duchenne Muscular Dystrophy-Associated Cardiomyopathy in mdx Mice. (Gartz M, Haberman M, Prom MJ, Beatka MJ, Strande JL, Lawlor MW) J Cardiovasc Pharmacol Ther 2022;27:10742484221088655 1 Citation |
| 9 | Cardiometabolic effects of DOCA-salt in male C57BL/6J mice are variably dependent on sodium and nonsodium components of diet. (Patil CN, Ritter ML, Wackman KK, Oliveira V, Balapattabi K, Grobe CC, Brozoski DT, Reho JJ, Nakagawa P, Mouradian GC Jr, Kriegel AJ, Kwitek AE, Hodges MR, Segar JL, Sigmund CD, Grobe JL) Am J Physiol Regul Integr Comp Physiol 2022 Jun 01;322(6):R467-R485 9 Citations |
| 1 | Isolation of Innate Lymphoid Cells from Murine Intestinal Lamina Propria. (Mei A, Hashemi E, Khalil M, Wang D, Malarkannan S) Methods Mol Biol 2022;2463:3-9 1 Citation |
| 2 | Method to Study Adaptive NK Cells Following MCMV Infections. (Khalil M, Mei A, Hashemi E, Wang D, Schumacher M, Terhune S, Malarkannan S) Methods Mol Biol 2022;2463:195-204 |
| 1 | Imaging Mass Spectrometry Reveals Alterations in N-Linked Glycosylation That Are Associated With Histopathological Changes in Nonalcoholic Steatohepatitis in Mouse and Human. (Ochoa-Rios S, O'Connor IP, Kent LN, Clouse JM, Hadjiyannis Y, Koivisto C, Pecot T, Angel PM, Drake RR, Leone G, Mehta AS, Rockey DC) Mol Cell Proteomics 2022 May;21(5):100225 10 Citations |
| 1 | Cowpea Mosaic Virus Outperforms Other Members of the Secoviridae as In Situ Vaccine for Cancer Immunotherapy. (Beiss V, Mao C, Fiering SN, Steinmetz NF) Mol Pharm 2022 May 02;19(5):1573-1585 20 Citations |
| 1 | Baicalein inhibits cell proliferation and enhances apoptosis in human A549 cells and benzo(a)pyrene-induced pulmonary carcinogenesis in mice. (Chandrashekar N, Subramanian R, Thiruvengadam D) J Biochem Mol Toxicol 2022 Jul;36(7):e23053 5 Citations |
| 1 | Epidermal 1-O-acylceramides appear with the establishment of the water permeability barrier in mice and are produced by maturating keratinocytes. (Rabionet M, Bernard P, Pichery M, Marsching C, Bayerle A, Dworski S, Kamani MA, Chitraju C, Gluchowski NL, Gabriel KR, Asadi A, Ebel P, Hoekstra M, Dumas S, Ntambi JM, Jacobsson A, Willecke K, Medin JA, Jonca N, Sandhoff R) Lipids 2022 May;57(3):183-195 6 Citations |
| 1 | Autistic-like behavior and cerebellar dysfunction in Bmal1 mutant mice ameliorated by mTORC1 inhibition. (Liu D, Nanclares C, Simbriger K, Fang K, Lorsung E, Le N, Amorim IS, Chalkiadaki K, Pathak SS, Li J, Gewirtz JC, Jin VX, Kofuji P, Araque A, Orr HT, Gkogkas CG, Cao R) Mol Psychiatry 2023 Sep;28(9):3727-3738 26 Citations |
| 2 | Autologous, lentivirus-modified, T-rapa cell "micropharmacies" for lysosomal storage disorders. (Nagree MS, Felizardo TC, Faber ML, Rybova J, Rupar CA, Foley SR, Fuller M, Fowler DH, Medin JA) EMBO Mol Med 2022 Apr 07;14(4):e14297 6 Citations |
| 1 | A novel hybrid peptide composed of LfcinB6 and KR-12-a4 with enhanced antimicrobial, anti-inflammatory and anti-biofilm activities. (Ajish C, Yang S, Kumar SD, Kim EY, Min HJ, Lee CW, Shin SH, Shin SY) Sci Rep 2022 Mar 14;12(1):4365 27 Citations |
| 2 | Deep learning tools and modeling to estimate the temporal expression of cell cycle proteins from 2D still images. (Pécot T, Cuitiño MC, Johnson RH, Timmers C, Leone G) PLoS Comput Biol 2022 Mar;18(3):e1009949 6 Citations |
| 2 | Contextual control of conditioned pain tolerance and endogenous analgesic systems. (Trask S, Mogil JS, Helmstetter FJ, Stucky CL, Sadler KE) Elife 2022 Mar 11;11 5 Citations |
| 1 | S-SCAM inhibits Axin-dependent synaptic function of GSK3β in a sex-dependent manner. (Kearney G, Grau D, Nieves Torres D, Shin SM, Lee SH) Sci Rep 2022 Mar 08;12(1):4090 1 Citation |
| 4 | Chronic stress promotes an immunologic inflammatory state and head and neck cancer growth in a humanized murine model. (Zenga J, Awan MJ, Frei A, Petrie E, Sharma GP, Shreenivas A, Shukla M, Himburg HA) Head Neck 2022 Jun;44(6):1324-1334 4 Citations |
| 1 | Comparative pharmacodynamic and pharmacokinetic study of MIDD0301 and its (S) enantiomer. (Rashid Roni MS, Zahn NM, Yocum GT, Webb DA, Mian MY, Meyer MJ, Tylek AS, Cook JM, Emala CW, Stafford DC, Arnold LA) Drug Dev Res 2022 Jun;83(4):979-992 1 Citation |
| 1 | VU6036720: The First Potent and Selective In Vitro Inhibitor of Heteromeric Kir4.1/5.1 Inward Rectifier Potassium Channels. (McClenahan SJ, Kent CN, Kharade SV, Isaeva E, Williams JC, Han C, Terker A, Gresham R 3rd, Lazarenko RM, Days EL, Romaine IM, Bauer JA, Boutaud O, Sulikowski GA, Harris R, Weaver CD, Staruschenko A, Lindsley CW, Denton JS) Mol Pharmacol 2022 May;101(5):357-370 11 Citations |
| 3 | The Synthesis and Anti-Cytomegalovirus Activity of Piperidine-4-Carboxamides. (Guo X, Ghosh AK, Keyes RF, Peterson F, Forman M, Meyers DJ, Arav-Boger R) Viruses 2022 Jan 25;14(2) 2 Citations |
| 1 | Gut Microbiota Regulate Pancreatic Growth, Exocrine Function, and Gut Hormones. (Girdhar K, Soto M, Huang Q, Orliaguet L, Cederquist C, Sundaresh B, Hu J, Figura M, Raisingani A, Canfora EE, Dirice E, Fujisaka S, Goossens GH, Blaak EE, Kulkarni RN, Kahn CR, Altindis E) Diabetes 2022 May 01;71(5):945-960 16 Citations |
| 1 | Non-phosphorylatable cyclin D1 mutant potentiates endometrial hyperplasia and drives carcinoma with Pten loss. (Yoshida A, Phillips-Mason P, Tarallo V, Avril S, Koivisto C, Leone G, Diehl JA) Oncogene 2022 Apr;41(15):2187-2195 5 Citations |
| 1 | Insulin Prevents Hypercholesterolemia by Suppressing 12α-Hydroxylated Bile Acids. (Semova I, Levenson AE, Krawczyk J, Bullock K, Gearing ME, Ling AV, Williams KA, Miao J, Adamson SS, Shin DJ, Chahar S, Graham MJ, Crooke RM, Hagey LR, Vicent D, de Ferranti SD, Kidambi S, Clish CB, Biddinger SB) Circulation 2022 Mar 29;145(13):969-982 21 Citations |
| 1 | Single-Cell Transcriptomic and Epigenetic Analyses of Mouse Mammary Development Starting with the Embryo. (Ma Z, Lytle NK, Ramos C, Naeem RF, Wahl GM) Methods Mol Biol 2022;2471:49-82 1 Citation |
| 1 | Analogs of the Heat Shock Protein 70 Inhibitor MKT-077 Suppress Medullary Thyroid Carcinoma Cells. (Hong SK, Starenki D, Johnson OT, Gestwicki JE, Park JI) Int J Mol Sci 2022 Jan 19;23(3) 12 Citations |
| 1 | Downregulation of low-density lipoprotein receptor mRNA in lymphatic endothelial cells impairs lymphatic function through changes in intracellular lipids. (Vachon L, Smaani A, Tessier N, Jean G, Demers A, Milasan A, Ardo N, Jarry S, Villeneuve L, Alikashani A, Finherty V, Ruiz M, Sorci-Thomas MG, Mayer G, Martel C) Theranostics 2022;12(3):1440-1458 8 Citations |
| 1 | NAD+ Levels Are Augmented in Aortic Tissue of ApoE-/- Mice by Dietary Omega-3 Fatty Acids. (Chi DH, Kahyo T, Islam A, Hasan MM, Waliullah ASM, Mamun MA, Nakajima M, Ikoma T, Akita K, Maekawa Y, Sato T, Setou M) Arterioscler Thromb Vasc Biol 2022 Apr;42(4):395-406 7 Citations |
| 1 | Comparison of prefrontal cortex sucrose seeking ensembles engaged in multiple seeking sessions: Context is key. (Jessen K, Slaker Bennett ML, Liu S, Olsen CM) J Neurosci Res 2022 Apr;100(4):1008-1029 5 Citations |
| 1 | RBFOX2 is required for establishing RNA regulatory networks essential for heart development. (Verma SK, Deshmukh V, Thatcher K, Belanger KK, Rhyner AM, Meng S, Holcomb RJ, Bressan M, Martin JF, Cooke JP, Wythe JD, Widen SG, Lincoln J, Kuyumcu-Martinez MN) Nucleic Acids Res 2022 Feb 28;50(4):2270-2286 25 Citations |
| 3 | Development of a Novel, Small-Molecule Brain-Penetrant Histone Deacetylase Inhibitor That Enhances Spatial Memory Formation in Mice. (Belayet JB, Beamish S, Rahaman M, Alanani S, Virdi RS, Frick DN, Rahman AFMT, Ulicki JS, Biswas S, Arnold LA, Roni MSR, Cheng EY, Steeber DA, Frick KM, Hossain MM) J Med Chem 2022 Feb 24;65(4):3388-3403 6 Citations |
| 1 | Antigen cross-presentation in young tumor-bearing hosts promotes CD8+ T cell terminal differentiation. (Moustaki A, Crawford JC, Alli S, Fan Y, Boi S, Zamora AE, McDonald NMN, Wu G, Nakitandwe J, Newman S, Foy S, Silkov A, Thomas PG, Pappo A, Dyer MA, Stewart E, Federico S, Youngblood B) Sci Immunol 2022 Feb 04;7(68):eabf6136 10 Citations |
| 1 | Tissue-specific expression of myosin phosphatase subunits and isoforms in smooth muscle of mice and humans. (Oslin K, Reho JJ, Lu Y, Khanal S, Kenchegowda D, Prior SJ, Fisher SA) Am J Physiol Regul Integr Comp Physiol 2022 Apr 01;322(4):R281-R291 3 Citations |
| 1 | APOE4 genotype or ovarian hormone loss influence open field exploration in an EFAD mouse model of Alzheimer's disease. (Taxier LR, Philippi SM, York JM, LaDu MJ, Frick KM) Horm Behav 2022 Apr;140:105124 10 Citations |
| 2 | Isoform-specific and cell/tissue-dependent effects of p38 MAPKs in regulating inflammation and inflammation-associated oncogenesis. (Qin JZ, Xin H, Qi XM, Chen G) Front Biosci (Landmark Ed) 2022 Jan 18;27(1):31 9 Citations |
| 3 | Critical Role for Cap-Independent c-MYC Translation in Progression of Multiple Myeloma. (Shi Y, Sun F, Cheng Y, Holmes B, Dhakal B, Gera JF, Janz S, Lichtenstein A) Mol Cancer Ther 2022 Apr 01;21(4):502-510 5 Citations |
| 3 | Nicotinamide Riboside-Conditioned Microbiota Deflects High-Fat Diet-Induced Weight Gain in Mice. (Lozada-Fernández VV, deLeon O, Kellogg SL, Saravia FL, Hadiono MA, Atkinson SN, Grobe JL, Kirby JR) mSystems 2022 Feb 22;7(1):e0023021 13 Citations |
| 2 | MicroRNA-31 regulates T-cell metabolism via HIF1α and promotes chronic GVHD pathogenesis in mice. (Wu Y, Mealer C, Schutt S, Wilson CL, Bastian D, Sofi MH, Zhang M, Luo Z, Choi HJ, Yang K, Tian L, Nguyen H, Helke K, Schnapp LM, Wang H, Yu XZ) Blood Adv 2022 May 24;6(10):3036-3052 9 Citations |
| 1 | The detrimental effects of APOE4 on risk for Alzheimer's disease may result from altered dendritic spine density, synaptic proteins, and estrogen receptor alpha. (Taxier LR, Philippi SM, York JM, LaDu MJ, Frick KM) Neurobiol Aging 2022 Apr;112:74-86 14 Citations |
| 1 | Decorin regulates collagen fibrillogenesis during corneal wound healing in mouse in vivo. (Gupta S, Buyank F, Sinha NR, Grant DG, Sinha PR, Iozzo RV, Chaurasia SS, Mohan RR) Exp Eye Res 2022 Mar;216:108933 20 Citations |
| 2 | Differential roles of BAF and PBAF subunits, Arid1b and Arid2, in MLL-AF9 leukemogenesis. (Bluemn T, Schmitz J, Zheng Y, Burns R, Zheng S, DeJong J, Christiansen L, Arnold O, Izaguirre-Carbonell J, Wang D, Deshpande AJ, Zhu N) Leukemia 2022 Apr;36(4):946-955 11 Citations |
| 1 | Quiescent human glioblastoma cancer stem cells drive tumor initiation, expansion, and recurrence following chemotherapy. (Xie XP, Laks DR, Sun D, Ganbold M, Wang Z, Pedraza AM, Bale T, Tabar V, Brennan C, Zhou X, Parada LF) Dev Cell 2022 Jan 10;57(1):32-46.e8 95 Citations |
| 1 | Clinical impact of glycans in platelet and megakaryocyte biology. (Falet H, Rivadeneyra L, Hoffmeister KM) Blood 2022 Jun 02;139(22):3255-3263 11 Citations |
| 1 | A novel mouse model of type 2N VWD was developed by CRISPR/Cas9 gene editing and recapitulates human type 2N VWD. (Shi Q, Fahs SA, Mattson JG, Yu H, Perry CL, Morateck PA, Schroeder JA, Rapten J, Weiler H, Montgomery RR) Blood Adv 2022 May 10;6(9):2778-2790 5 Citations |
| 1 | NSAID-Induced Enteropathy Affects Regulation of Hepatic Glucose Production by Decreasing GLP-1 Secretion. (Herz H, Song Y, Ye Y, Tian L, Linden B, Abu El Haija M, Chu Y, Grobe JL, Lengeling RW, Mokadem M) Nutrients 2021 Dec 28;14(1) 4 Citations |
| 1 | A peripheral CB2 cannabinoid receptor mechanism suppresses chemotherapy-induced peripheral neuropathy: evidence from a CB2 reporter mouse. (Lin X, Xu Z, Carey L, Romero J, Makriyannis A, Hillard CJ, Ruggiero E, Dockum M, Houk G, Mackie K, Albrecht PJ, Rice FL, Hohmann AG) Pain 2022 May 01;163(5):834-851 20 Citations |
| 3 | Short-term Housing in Metabolic Caging on Measures of Energy and Fluid Balance in Male C57BL/6J Mice ( Mus musculus). (Ziegler AA, Grobe CC, Reho JJ, Jensen ES, Thulin JD, Segar JL, Grobe JL) J Am Assoc Lab Anim Sci 2022 Mar 01;61(2):132-139 12 Citations |
| 1 | Sonobiopsy for minimally invasive, spatiotemporally-controlled, and sensitive detection of glioblastoma-derived circulating tumor DNA. (Pacia CP, Yuan J, Yue Y, Xu L, Nazeri A, Desai R, Gach HM, Wang X, Talcott MR, Chaudhuri AA, Dunn GP, Leuthardt EC, Chen H) Theranostics 2022;12(1):362-378 38 Citations |
| 1 | Inactivated Cowpea Mosaic Virus in Combination with OX40 Agonist Primes Potent Antitumor Immunity in a Bilateral Melanoma Mouse Model. (Koellhoffer EC, Mao C, Beiss V, Wang L, Fiering SN, Boone CE, Steinmetz NF) Mol Pharm 2022 Feb 07;19(2):592-601 11 Citations |
| 1 | Suppression of fibrin(ogen)-driven pathologies in disease models through controlled knockdown by lipid nanoparticle delivery of siRNA. (Juang LJ, Hur WS, Silva LM, Strilchuk AW, Francisco B, Leung J, Robertson MK, Groeneveld DJ, La Prairie B, Chun EM, Cap AP, Luyendyk JP, Palumbo JS, Cullis PR, Bugge TH, Flick MJ, Kastrup CJ) Blood 2022 Mar 03;139(9):1302-1311 17 Citations |
| 1 | Myelin-associated glycoprotein activation triggers glutamate uptake by oligodendrocytes in vitro and contributes to ameliorate glutamate-mediated toxicity in vivo. (Vivinetto AL, Castañares C, Garcia-Keller C, Moyano AL, Falcon C, Palandri A, Rozés-Salvador V, Rojas JI, Patrucco L, Monferran C, Cancela L, Cristiano E, Schnaar RL, Lopez PHH) Biochim Biophys Acta Mol Basis Dis 2022 Apr 01;1868(4):166324 3 Citations |
| 2 | The Neuroprotective Effects of the CB2 Agonist GW842166x in the 6-OHDA Mouse Model of Parkinson's Disease. (Yu H, Liu X, Chen B, Vickstrom CR, Friedman V, Kelly TJ, Bai X, Zhao L, Hillard CJ, Liu QS) Cells 2021 Dec 16;10(12) 25 Citations |
| 1 | Adolescent THC Treatment Does Not Potentiate the Behavioral Effects in Adulthood of Maternal Immune Activation. (Stollenwerk TM, Hillard CJ) Cells 2021 Dec 11;10(12) 12 Citations |
| 2 | Donor T-Cell Repertoire Profiling in Recipient Lymphoid and Parenchyma Organs Reveals GVHD Pathogenesis at Clonal Levels After Bone Marrow Transplantation in Mice. (Wu Y, Fu J, Wang H, Yu XZ) Front Immunol 2021;12:778996 4 Citations |
| 1 | Disruption of Circadian Rhythms by Ambient Light during Neurodevelopment Leads to Autistic-like Molecular and Behavioral Alterations in Adult Mice. (Fang K, Liu D, Pathak SS, Yang B, Li J, Karthikeyan R, Chao OY, Yang YM, Jin VX, Cao R) Cells 2021 Nov 26;10(12) 18 Citations |
| 1 | Fibrin is a critical regulator of neutrophil effector function at the oral mucosal barrier. (Silva LM, Doyle AD, Greenwell-Wild T, Dutzan N, Tran CL, Abusleme L, Juang LJ, Leung J, Chun EM, Lum AG, Agler CS, Zuazo CE, Sibree M, Jani P, Kram V, Martin D, Moss K, Lionakis MS, Castellino FJ, Kastrup CJ, Flick MJ, Divaris K, Bugge TH, Moutsopoulos NM) Science 2021 Dec 24;374(6575):eabl5450 114 Citations |
| 1 | Cytokine and Nitric Oxide-Dependent Gene Regulation in Islet Endocrine and Nonendocrine Cells. (Stancill JS, Kasmani MY, Khatun A, Cui W, Corbett JA) Function (Oxf) 2022;3(1):zqab063 10 Citations |
| 1 | Establishment of In Vivo Ovarian Cancer Mouse Models Using Intraperitoneal Tumor Cell Injection. (Mittal S, Gupta P, Chaluvally-Raghavan P, Pradeep S) Methods Mol Biol 2022;2424:247-254 4 Citations |
| 1 | Hypofibrinogenemia with preserved hemostasis and protection from thrombosis in mice with an Fga truncation mutation. (Hur WS, Paul DS, Bouck EG, Negrón OA, Mwiza JM, Poole LG, Cline-Fedewa HM, Clark EG, Juang LJ, Leung J, Kastrup CJ, Ugarova TP, Wolberg AS, Luyendyk JP, Bergmeier W, Flick MJ) Blood 2022 Mar 03;139(9):1374-1388 19 Citations |
| 1 | Development of novel phenoxyalkylpiperidines as high-affinity Sigma-1 (σ1) receptor ligands with potent anti-amnesic effect. (Abatematteo FS, Mosier PD, Niso M, Brunetti L, Berardi F, Loiodice F, Contino M, Delprat B, Maurice T, Laghezza A, Abate C) Eur J Med Chem 2022 Jan 15;228:114038 3 Citations |
| 1 | Reduced cleavage of von willebrand factor by ADAMTS13 is associated with microangiopathic acute kidney injury following trauma. (Plautz WE, Haldeman SH, Dyer MR, Sperry JL, Guyette FX, Loughran PA, Alvikas J, Hassoune A, Hoteit L, Alsaadi N, Zuckerbraun BS, Rollins-Raval MA, Raval JS, Mota RI, Neal MD, A TACTIC Publication) Blood Coagul Fibrinolysis 2022 Jan 01;33(1):14-24 12 Citations |
| 1 | Genomic attributes of homology-directed DNA repair deficiency in metastatic prostate cancer. (De Sarkar N, Dasgupta S, Chatterjee P, Coleman I, Ha G, Ang LS, Kohlbrenner EA, Frank SB, Nunez TA, Salipante SJ, Corey E, Morrissey C, Van Allen E, Schweizer MT, Haffner MC, Patel R, Hanratty B, Lucas JM, Dumpit RF, Pritchard CC, Montgomery RB, Nelson PS) JCI Insight 2021 Dec 08;6(23) 16 Citations |
| 2 | WDR26 and MTF2 are therapeutic targets in multiple myeloma. (Sun F, Cheng Y, Riordan JD, Dupuy A, Dubois W, Pisano M, Dong J, Mock B, Zhan F, Hari P, Janz S) J Hematol Oncol 2021 Dec 07;14(1):203 7 Citations |
| 1 | Identification and Quantification of MIDD0301 Metabolites. (Roni MSR, Zahn NM, Mikulsky BN, Webb DA, Mian MY, Knutson DE, Guthrie ML, Cook JM, Stafford DC, Arnold LA) Curr Drug Metab 2021;22(14):1114-1123 2 Citations |
| 1 | Neuropilin 1 regulates bone marrow vascular regeneration and hematopoietic reconstitution. (Termini CM, Pang A, Fang T, Roos M, Chang VY, Zhang Y, Setiawan NJ, Signaevskaia L, Li M, Kim MM, Tabibi O, Lin PK, Sasine JP, Chatterjee A, Murali R, Himburg HA, Chute JP) Nat Commun 2021 Nov 30;12(1):6990 29 Citations |
| 1 | Muscle-directed gene therapy corrects Pompe disease and uncovers species-specific GAA immunogenicity. (Eggers M, Vannoy CH, Huang J, Purushothaman P, Brassard J, Fonck C, Meng H, Prom MJ, Lawlor MW, Cunningham J, Sadhu C, Mavilio F) EMBO Mol Med 2022 Jan 11;14(1):e13968 34 Citations |
| 1 | Chronic cannabis smoking-enriched oral pathobiont drives behavioral changes, macrophage infiltration, and increases β-amyloid protein production in the brain. (Luo Z, Fitting S, Robinson C, Benitez A, Li M, Wu Y, Fu X, Amato D, Ning W, Funderburg N, Wang X, Zhou Z, Yu X, Wagner A, Cong X, Xu W, Maas K, Wolf BJ, Huang L, Yu J, Scott A, Mcrae-Clark A, Hamlett ED, Jiang W) EBioMedicine 2021 Dec;74:103701 9 Citations |
| 1 | Mouse Homologue of Human HLA-DO Does Not Preempt Autoimmunity but Controls Murine Gammaherpesvirus MHV68. (Lee J, Cullum E, Stoltz K, Bachmann N, Strong Z, Millick DD, Denzin LK, Chang A, Tarakanova V, Chervonsky AV, Golovkina T) J Immunol 2021 Dec 15;207(12):2944-2951 2 Citations |
| 1 | DNA damage is overcome by TRIP13 overexpression during cisplatin nephrotoxicity. (Hama T, Nagesh PK, Chowdhury P, Moore BM 2nd, Yallapu MM, Regner KR, Park F) JCI Insight 2021 Nov 22;6(22) 8 Citations |
| 3 | Macrophage 12(S)-HETE Enhances Angiotensin II-Induced Contraction by a BLT2 (Leukotriene B4 Type-2 Receptor) and TP (Thromboxane Receptor)-Mediated Mechanism in Murine Arteries. (Kriska T, Herrnreiter A, Pfister SL, Adebesin A, Falck JR, Campbell WB) Hypertension 2022 Jan;79(1):104-114 8 Citations |
| 2 | Retinoic Acid Signaling Modulates Recipient Gut Barrier Integrity and Microbiota After Allogeneic Hematopoietic Stem Cell Transplantation in Mice. (Pan P, Atkinson SN, Taylor B, Zhu H, Zhou D, Flejsierowicz P, Wang LS, Morse M, Liu C, Gunsolus IL, Chen X) Front Immunol 2021;12:749002 7 Citations |
| 1 | (2-Aminopropyl)benzo[β]thiophenes (APBTs) are novel monoamine transporter ligands that lack stimulant effects but display psychedelic-like activity in mice. (Rudin D, McCorvy JD, Glatfelter GC, Luethi D, Szöllősi D, Ljubišić T, Kavanagh PV, Dowling G, Holy M, Jaentsch K, Walther D, Brandt SD, Stockner T, Baumann MH, Halberstadt AL, Sitte HH) Neuropsychopharmacology 2022 Mar;47(4):914-923 10 Citations |
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| 1 | Genetic and Developmental Contributors to Aortic Stenosis. (Dutta P, James JF, Kazik H, Lincoln J) Circ Res 2021 Apr 30;128(9):1330-1343 17 Citations |
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| 2 | Sarcoma IL-12 overexpression facilitates NK cell immunomodulation. (Rademacher MJ, Cruz A, Faber M, Oldham RAA, Wang D, Medin JA, Schloemer NJ) Sci Rep 2021 Apr 15;11(1):8321 13 Citations |
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| 1 | Gefitinib Inhibits Invasion and Metastasis of Osteosarcoma via Inhibition of Macrophage Receptor Interacting Serine-Threonine Kinase 2. (Maloney C, Kallis MP, Edelman M, Tzanavaris C, Lesser M, Soffer SZ, Symons M, Steinberg BM) Mol Cancer Ther 2020 Jun;19(6):1340-1350 18 Citations |
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| 1 | The CD137 Ligand Is Important for Type 1 Diabetes Development but Dispensable for the Homeostasis of Disease-Suppressive CD137+ FOXP3+ Regulatory CD4 T Cells. (Foda BM, Ciecko AE, Serreze DV, Ridgway WM, Geurts AM, Chen YG) J Immunol 2020 Jun 01;204(11):2887-2899 9 Citations |
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| 1 | The Adult Murine Intestine is Dependent on Constitutive Laminin-γ1 Synthesis. (Fields B, DeLaForest A, Zogg M, May J, Hagen C, Komnick K, Wieser J, Lundberg A, Weiler H, Battle MA, Carlson KS) Sci Rep 2019 Dec 17;9(1):19303 8 Citations |
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| 1 | Preclinical Assessment with Clinical Validation of Selinexor with Gemcitabine and Nab-Paclitaxel for the Treatment of Pancreatic Ductal Adenocarcinoma. (Azmi AS, Khan HY, Muqbil I, Aboukameel A, Neggers JE, Daelemans D, Mahipal A, Dyson G, Kamgar M, Al-Hallak MN, Tesfaye A, Kim S, Shidham V, M Mohammad R, Philip PA) Clin Cancer Res 2020 Mar 15;26(6):1338-1348 41 Citations |
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| 1 | Role of dopamine and selective dopamine receptor agonists on mouse ductus arteriosus tone and responsiveness. (Crockett SL, Harris M, Boatwright N, Su RL, Yarboro MT, Berger CD, Shelton EL, Reese J, Segar JL) Pediatr Res 2020 May;87(6):991-997 3 Citations |
| 1 | The Interleukin (IL) 17R/IL-22R Signaling Axis Is Dispensable for Vulvovaginal Candidiasis Regardless of Estrogen Status. (Peters BM, Coleman BM, Willems HME, Barker KS, Aggor FEY, Cipolla E, Verma AH, Bishu S, Huppler AH, Bruno VM, Gaffen SL) J Infect Dis 2020 Apr 07;221(9):1554-1563 39 Citations |
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| 1 | Soluble CD137 Ameliorates Acute Type 1 Diabetes by Inducing T Cell Anergy. (Itoh A, Ortiz L, Kachapati K, Wu Y, Adams D, Bednar K, Mukherjee S, Chougnet C, Mittler RS, Chen YG, Dolan L, Ridgway WM) Front Immunol 2019;10:2566 21 Citations |
| 1 | Gain-of-Function RHOA Mutations Promote Focal Adhesion Kinase Activation and Dependency in Diffuse Gastric Cancer. (Zhang H, Schaefer A, Wang Y, Hodge RG, Blake DR, Diehl JN, Papageorge AG, Stachler MD, Liao J, Zhou J, Wu Z, Akarca FG, de Klerk LK, Derks S, Pierobon M, Hoadley KA, Wang TC, Church G, Wong KK, Petricoin EF, Cox AD, Lowy DR, Der CJ, Bass AJ) Cancer Discov 2020 Feb;10(2):288-305 116 Citations |
| 1 | Endotoxin Engages Mitochondrial Quality Control via an iNOS-Reactive Oxygen Species Signaling Pathway in Hepatocytes. (Cyr A, Chambers L, Waltz PK, Whelan SP, Kohut L, Carchman E, Dyer M, Luciano J, Kautza B, Gomez HD, Otterbein LE, Rosengart MR, Shiva S, Zuckerbraun BS) Oxid Med Cell Longev 2019;2019:4745067 14 Citations |
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| 1 | Plasticity of histone modifications around Cidea and Cidec genes with secondary bile in the amelioration of developmentally-programmed hepatic steatosis. (Urmi JF, Itoh H, Muramatsu-Kato K, Kohmura-Kobayashi Y, Hariya N, Jain D, Tamura N, Uchida T, Suzuki K, Ogawa Y, Shiraki N, Mochizuki K, Kubota T, Kanayama N) Sci Rep 2019 Nov 19;9(1):17100 8 Citations |
| 1 | Seasonal plasticity in GABAA signaling is necessary for restoring phase synchrony in the master circadian clock network. (Rohr KE, Pancholi H, Haider S, Karow C, Modert D, Raddatz NJ, Evans J) Elife 2019 Nov 20;8 30 Citations |
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| 1 | Protein lysine 43 methylation by EZH1 promotes AML1-ETO transcriptional repression in leukemia. (Dou L, Yan F, Pang J, Zheng D, Li D, Gao L, Wang L, Xu Y, Shi J, Wang Q, Zhou L, Shen N, Singh P, Wang L, Li Y, Gao Y, Liu T, Chen C, Al-Kali A, Litzow MR, Chi YI, Bode AM, Liu C, Huang H, Liu D, Marcucci G, Liu S, Yu L) Nat Commun 2019 Nov 07;10(1):5051 19 Citations |
| 1 | Coactivation of NF-κB and Notch signaling is sufficient to induce B-cell transformation and enables B-myeloid conversion. (Xiu Y, Dong Q, Fu L, Bossler A, Tang X, Boyce B, Borcherding N, Leidinger M, Sardina JL, Xue HH, Li Q, Feldman A, Aifantis I, Boccalatte F, Wang L, Jin M, Khoury J, Wang W, Hu S, Yuan Y, Wang E, Yuan J, Janz S, Colgan J, Habelhah H, Waldschmidt T, Müschen M, Bagg A, Darbro B, Zhao C) Blood 2020 Jan 09;135(2):108-120 18 Citations |
| 1 | Genome editing of HBG1 and HBG2 to induce fetal hemoglobin. (Métais JY, Doerfler PA, Mayuranathan T, Bauer DE, Fowler SC, Hsieh MM, Katta V, Keriwala S, Lazzarotto CR, Luk K, Neel MD, Perry SS, Peters ST, Porter SN, Ryu BY, Sharma A, Shea D, Tisdale JF, Uchida N, Wolfe SA, Woodard KJ, Wu Y, Yao Y, Zeng J, Pruett-Miller S, Tsai SQ, Weiss MJ) Blood Adv 2019 Nov 12;3(21):3379-3392 130 Citations |
| 1 | Induction of activated T follicular helper cells is critical for anti-FVIII inhibitor development in hemophilia A mice. (Jing W, Chen J, Cai Y, Chen Y, Schroeder JA, Johnson BD, Cui W, Shi Q) Blood Adv 2019 Oct 22;3(20):3099-3110 27 Citations |
| 1 | Novel variants in CDH2 are associated with a new syndrome including Peters anomaly. (Reis LM, Houssin NS, Zamora C, Abdul-Rahman O, Kalish JM, Zackai EH, Plageman TF Jr, Semina EV) Clin Genet 2020 Mar;97(3):502-508 15 Citations |
| 1 | Keratinocyte Growth Factor Reduces Injury and Leads to Early Recovery from Cyclophosphamide Bladder Injury. (Narla ST, Bushnell DS, Schaefer CM, Nouraie M, Bates CM) Am J Pathol 2020 Jan;190(1):108-124 17 Citations |
| 3 | The anthelmintic drug praziquantel activates a schistosome transient receptor potential channel. (Park SK, Gunaratne GS, Chulkov EG, Moehring F, McCusker P, Dosa PI, Chan JD, Stucky CL, Marchant JS) J Biol Chem 2019 Dec 06;294(49):18873-18880 69 Citations |
| 1 | Proteasome activation by insulin-like growth factor-1/nuclear factor erythroid 2-related factor 2 signaling promotes exercise-induced neurogenesis. (Niu X, Zhao Y, Yang N, Zhao X, Zhang W, Bai X, Li A, Yang W, Lu L) Stem Cells 2020 Feb;38(2):246-260 17 Citations |
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| 1 | Dorsal Hippocampal Actin Polymerization Is Necessary for Activation of G-Protein-Coupled Estrogen Receptor (GPER) to Increase CA1 Dendritic Spine Density and Enhance Memory Consolidation. (Kim J, Schalk JC, Koss WA, Gremminger RL, Taxier LR, Gross KS, Frick KM) J Neurosci 2019 Nov 27;39(48):9598-9610 37 Citations |
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| 1 | Within-animal comparisons of novelty and cocaine neuronal ensemble overlap in the nucleus accumbens and prefrontal cortex. (Nawarawong NN, Olsen CM) Behav Brain Res 2020 Feb 03;379:112275 7 Citations |
| 1 | Control of cytokinesis by β-adrenergic receptors indicates an approach for regulating cardiomyocyte endowment. (Liu H, Zhang CH, Ammanamanchi N, Suresh S, Lewarchik C, Rao K, Uys GM, Han L, Abrial M, Yimlamai D, Ganapathy B, Guillermier C, Chen N, Khaladkar M, Spaethling J, Eberwine JH, Kim J, Walsh S, Choudhury S, Little K, Francis K, Sharma M, Viegas M, Bais A, Kostka D, Ding J, Bar-Joseph Z, Wu Y, Yechoor V, Moulik M, Johnson J, Weinberg J, Reyes-Múgica M, Steinhauser ML, Kühn B) Sci Transl Med 2019 Oct 09;11(513) 85 Citations |
| 1 | B Cell-Intrinsic SHP1 Expression Promotes the Gammaherpesvirus-Driven Germinal Center Response and the Establishment of Chronic Infection. (Johnson KE, Lange PT, Jondle CN, Volberding PJ, Lorenz UM, Cui W, Dittel BN, Tarakanova VL) J Virol 2019 Dec 12;94(1) 10 Citations |
| 1 | Neuronal network remodeling and Wnt pathway dysregulation in the intra-hippocampal kainate mouse model of temporal lobe epilepsy. (Gupta K, Schnell E) PLoS One 2019;14(10):e0215789 17 Citations |
| 1 | Phenolic compounds from nutmeg (Myristica fragrans Houtt.) inhibit the endocannabinoid-modulating enzyme fatty acid amide hydrolase. (El-Alfy AT, Abourashed EA, Patel C, Mazhari N, An H, Jeon A) J Pharm Pharmacol 2019 Dec;71(12):1879-1889 21 Citations |
| 3 | SOD2 acetylation on lysine 68 promotes stem cell reprogramming in breast cancer. (He C, Danes JM, Hart PC, Zhu Y, Huang Y, de Abreu AL, O'Brien J, Mathison AJ, Tang B, Frasor JM, Wakefield LM, Ganini D, Stauder E, Zielonka J, Gantner BN, Urrutia RA, Gius D, Bonini MG) Proc Natl Acad Sci U S A 2019 Nov 19;116(47):23534-23541 62 Citations |
| 1 | In vivo longitudinal imaging of RNA interference-induced endocrine therapy resistance in breast cancer. (Biswal NC, Fu X, Jagtap JM, Shea MJ, Kumar V, Lords T, Roy R, Schiff R, Joshi A) J Biophotonics 2020 Jan;13(1):e201900180 1 Citation |
| 2 | Vibrodissociation method for isolation of defined nephron segments from human and rodent kidneys. (Isaeva E, Fedoriuk M, Bohovyk R, Klemens CA, Khedr S, Golosova D, Levchenko V, El-Meanawy A, Palygin O, Staruschenko A) Am J Physiol Renal Physiol 2019 Nov 01;317(5):F1398-F1403 10 Citations |
| 1 | Tnni3k alleles influence ventricular mononuclear diploid cardiomyocyte frequency. (Gan P, Patterson M, Velasquez A, Wang K, Tian D, Windle JJ, Tao G, Judge DP, Makita T, Park TJ, Sucov HM) PLoS Genet 2019 Oct;15(10):e1008354 28 Citations |
| 1 | A Transcriptionally Definable Subgroup of Triple-Negative Breast and Ovarian Cancer Samples Shows Sensitivity to HSP90 Inhibition. (Shee K, Wells JD, Ung M, Hampsch RA, Traphagen NA, Yang W, Liu SC, Zeldenrust MA, Wang L, Kalari KR, Yu J, Boughey JC, Demidenko E, Kettenbach AN, Cheng C, Goetz MP, Miller TW) Clin Cancer Res 2020 Jan 01;26(1):159-170 1 Citation |
| 2 | Enzalutamide-Induced Feed-Forward Signaling Loop Promotes Therapy-Resistant Prostate Cancer Growth Providing an Exploitable Molecular Target for Jak2 Inhibitors. (Udhane V, Maranto C, Hoang DT, Gu L, Erickson A, Devi S, Talati PG, Banerjee A, Iczkowski KA, Jacobsohn K, See WA, Mirtti T, Kilari D, Nevalainen MT) Mol Cancer Ther 2020 Jan;19(1):231-246 20 Citations |
| 1 | Mitochondrial protein import is regulated by p17/PERMIT to mediate lipid metabolism and cellular stress. (Oleinik N, Kim J, Roth BM, Selvam SP, Gooz M, Johnson RH, Lemasters JJ, Ogretmen B) Sci Adv 2019 Sep;5(9):eaax1978 40 Citations |
| 1 | The eIF2α Kinase GCN2 Modulates Period and Rhythmicity of the Circadian Clock by Translational Control of Atf4. (Pathak SS, Liu D, Li T, de Zavalia N, Zhu L, Li J, Karthikeyan R, Alain T, Liu AC, Storch KF, Kaufman RJ, Jin VX, Amir S, Sonenberg N, Cao R) Neuron 2019 Nov 20;104(4):724-735.e6 54 Citations |
| 2 | Nongenotoxic antibody-drug conjugate conditioning enables safe and effective platelet gene therapy of hemophilia A mice. (Gao C, Schroeder JA, Xue F, Jing W, Cai Y, Scheck A, Subramaniam S, Rao S, Weiler H, Czechowicz A, Shi Q) Blood Adv 2019 Sep 24;3(18):2700-2711 43 Citations |
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| 1 | Peptide/Receptor Co-evolution Explains the Lipolytic Function of the Neuropeptide TLQP-21. (Sahu BS, Rodriguez P, Nguyen ME, Han R, Cero C, Razzoli M, Piaggi P, Laskowski LJ, Pavlicev M, Muglia L, Mahata SK, O'Grady S, McCorvy JD, Baier LJ, Sham YY, Bartolomucci A) Cell Rep 2019 Sep 03;28(10):2567-2580.e6 20 Citations |
| 1 | All trans-retinoic acid protects against acute ischemic stroke by modulating neutrophil functions through STAT1 signaling. (Cai W, Wang J, Hu M, Chen X, Lu Z, Bellanti JA, Zheng SG) J Neuroinflammation 2019 Aug 31;16(1):175 74 Citations |
| 1 | Position β57 of I-Ag7 controls early anti-insulin responses in NOD mice, linking an MHC susceptibility allele to type 1 diabetes onset. (Gioia L, Holt M, Costanzo A, Sharma S, Abe B, Kain L, Nakayama M, Wan X, Su A, Mathews C, Chen YG, Unanue E, Teyton L) Sci Immunol 2019 Aug 30;4(38) 40 Citations |
| 1 | Regulatory T Cells Control PF4/Heparin Antibody Production in Mice. (Zheng Y, Zhu W, Haribhai D, Williams CB, Aster RH, Wen R, Wang D) J Immunol 2019 Oct 01;203(7):1786-1792 11 Citations |
| 1 | Behavior, body composition, and vascular phenotype of homocystinuric mice on methionine-restricted diet or enzyme replacement therapy. (Majtan T, Park I, Cox A, Branchford BR, di Paola J, Bublil EM, Kraus JP) FASEB J 2019 Nov;33(11):12477-12486 19 Citations |
| 1 | Synergistic Genetic Interactions between Pkhd1 and Pkd1 Result in an ARPKD-Like Phenotype in Murine Models. (Olson RJ, Hopp K, Wells H, Smith JM, Furtado J, Constans MM, Escobar DL, Geurts AM, Torres VE, Harris PC) J Am Soc Nephrol 2019 Nov;30(11):2113-2127 38 Citations |
| 1 | Smooth Muscle Cell-Specific Disruption of the BBSome Causes Vascular Dysfunction. (Reho JJ, Guo DF, Morgan DA, Rahmouni K) Hypertension 2019 Oct;74(4):817-825 12 Citations |
| 1 | Gtf2i and Gtf2ird1 mutation do not account for the full phenotypic effect of the Williams syndrome critical region in mouse models. (Kopp N, McCullough K, Maloney SE, Dougherty JD) Hum Mol Genet 2019 Oct 15;28(20):3443-3465 16 Citations |
| 1 | Large Particle Fluorescence-Activated Cell Sorting Enables High-Quality Single-Cell RNA Sequencing and Functional Analysis of Adult Cardiomyocytes. (Kannan S, Miyamoto M, Lin BL, Zhu R, Murphy S, Kass DA, Andersen P, Kwon C) Circ Res 2019 Aug 16;125(5):567-569 34 Citations |
| 1 | PTPσ inhibitors promote hematopoietic stem cell regeneration. (Zhang Y, Roos M, Himburg H, Termini CM, Quarmyne M, Li M, Zhao L, Kan J, Fang T, Yan X, Pohl K, Diers E, Jin Gim H, Damoiseaux R, Whitelegge J, McBride W, Jung ME, Chute JP) Nat Commun 2019 Aug 14;10(1):3667 27 Citations |
| 1 | Pro-Survival Lipid Sphingosine-1-Phosphate Metabolically Programs T Cells to Limit Anti-tumor Activity. (Chakraborty P, Vaena SG, Thyagarajan K, Chatterjee S, Al-Khami A, Selvam SP, Nguyen H, Kang I, Wyatt MW, Baliga U, Hedley Z, Ngang RN, Guo B, Beeson GC, Husain S, Paulos CM, Beeson CC, Zilliox MJ, Hill EG, Mehrotra M, Yu XZ, Ogretmen B, Mehrotra S) Cell Rep 2019 Aug 13;28(7):1879-1893.e7 77 Citations |
| 1 | Identification and Characterization of Tumor-Initiating Cells in Multiple Myeloma. (Gao M, Bai H, Jethava Y, Wu Y, Zhu Y, Yang Y, Xia J, Cao H, Franqui-Machin R, Nadiminti K, Thomas GS, Salama ME, Altevogt P, Bishop G, Tomasson M, Janz S, Shi J, Chen L, Frech I, Tricot G, Zhan F) J Natl Cancer Inst 2020 May 01;112(5):507-515 40 Citations |
| 1 | Macrophages Educated with Exosomes from Primed Mesenchymal Stem Cells Treat Acute Radiation Syndrome by Promoting Hematopoietic Recovery. (Kink JA, Forsberg MH, Reshetylo S, Besharat S, Childs CJ, Pederson JD, Gendron-Fitzpatrick A, Graham M, Bates PD, Schmuck EG, Raval A, Hematti P, Capitini CM) Biol Blood Marrow Transplant 2019 Nov;25(11):2124-2133 46 Citations |
| 1 | Modeling Human Cancer-induced Cachexia. (Talbert EE, Cuitiño MC, Ladner KJ, Rajasekerea PV, Siebert M, Shakya R, Leone GW, Ostrowski MC, Paleo B, Weisleder N, Reiser PJ, Webb A, Timmers CD, Eiferman DS, Evans DC, Dillhoff ME, Schmidt CR, Guttridge DC) Cell Rep 2019 Aug 06;28(6):1612-1622.e4 93 Citations |
| 3 | Modification of HDL by reactive aldehydes alters select cardioprotective functions of HDL in macrophages. (Schill RL, Knaack DA, Powers HR, Chen Y, Yang M, Schill DJ, Silverstein RL, Sahoo D) FEBS J 2020 Feb;287(4):695-707 14 Citations |
| 2 | Adverse early-life environment impairs postnatal lung development in mice. (Lai PY, Jing X, Michalkiewicz T, Entringer B, Ke X, Majnik A, Kriegel AJ, Liu P, Lane RH, Konduri GG) Physiol Genomics 2019 Sep 01;51(9):462-470 14 Citations |
| 2 | Cryo-EM structure of TRPC5 at 2.8-Å resolution reveals unique and conserved structural elements essential for channel function. (Duan J, Li J, Chen GL, Ge Y, Liu J, Xie K, Peng X, Zhou W, Zhong J, Zhang Y, Xu J, Xue C, Liang B, Zhu L, Liu W, Zhang C, Tian XL, Wang J, Clapham DE, Zeng B, Li Z, Zhang J) Sci Adv 2019 Jul;5(7):eaaw7935 80 Citations |
| 1 | Metal-independent variants of phosphoglycerate mutase promote resistance to nutritional immunity and retention of glycolysis during infection. (Radin JN, Kelliher JL, Solórzano PKP, Grim KP, Ramezanifard R, Slauch JM, Kehl-Fie TE) PLoS Pathog 2019 Jul;15(7):e1007971 27 Citations |
| 2 | NOD-like receptor protein 3 inflammasome drives postoperative mechanical pain in a sex-dependent manner. (Cowie AM, Menzel AD, O'Hara C, Lawlor MW, Stucky CL) Pain 2019 Aug;160(8):1794-1816 41 Citations |
| 1 | FAM83D directs protein kinase CK1α to the mitotic spindle for proper spindle positioning. (Fulcher LJ, He Z, Mei L, Macartney TJ, Wood NT, Prescott AR, Whigham AJ, Varghese J, Gourlay R, Ball G, Clarke R, Campbell DG, Maxwell CA, Sapkota GP) EMBO Rep 2019 Sep;20(9):e47495 26 Citations |
| 1 | Neogenin-loss in neural crest cells results in persistent hyperplastic primary vitreous formation. (Lin S, Liu W, Chen CL, Sun D, Hu JX, Li L, Ye J, Mei L, Xiong WC) J Mol Cell Biol 2020 Jan 22;12(1):17-31 13 Citations |
| 1 | β-carboline alkaloids attenuate bleomycin induced pulmonary fibrosis in mice through inhibiting NF-kb/p65 phosphorylation and epithelial-mesenchymal transition. (Cui Y, Jiang L, Yu R, Shao Y, Mei L, Tao Y) J Ethnopharmacol 2019 Oct 28;243:112096 36 Citations |
| 1 | Abrupt involution induces inflammation, estrogenic signaling, and hyperplasia linking lack of breastfeeding with increased risk of breast cancer. (Basree MM, Shinde N, Koivisto C, Cuitino M, Kladney R, Zhang J, Stephens J, Palettas M, Zhang A, Kim HK, Acero-Bedoya S, Trimboli A, Stover DG, Ludwig T, Ganju R, Weng D, Shields P, Freudenheim J, Leone GW, Sizemore GM, Majumder S, Ramaswamy B) Breast Cancer Res 2019 Jul 17;21(1):80 35 Citations |
| 1 | Dynamin 2 is required for GPVI signaling and platelet hemostatic function in mice. (Eaton N, Drew C, Wieser J, Munday AD, Falet H) Haematologica 2020 May;105(5):1414-1423 8 Citations |
| 1 | In vivo generated hematopoietic stem cells from genome edited induced pluripotent stem cells are functional in platelet-targeted gene therapy of murine hemophilia A. (Wang D, Zhang G, Gu J, Shao X, Dai Y, Li J, Pan X, Yao S, Xu A, Jin Y, Huang J, Shi Q, Zhu J, Xi X, Chen Z, Chen S) Haematologica 2020 Apr;105(4):e175-e179 9 Citations |
| 1 | Deletion of Tet proteins results in quantitative disparities during ESC differentiation partially attributable to alterations in gene expression. (Reimer M Jr, Pulakanti K, Shi L, Abel A, Liang M, Malarkannan S, Rao S) BMC Dev Biol 2019 Jul 08;19(1):16 8 Citations |
| 1 | Battery-free, fully implantable optofluidic cuff system for wireless optogenetic and pharmacological neuromodulation of peripheral nerves. (Zhang Y, Mickle AD, Gutruf P, McIlvried LA, Guo H, Wu Y, Golden JP, Xue Y, Grajales-Reyes JG, Wang X, Krishnan S, Xie Y, Peng D, Su CJ, Zhang F, Reeder JT, Vogt SK, Huang Y, Rogers JA, Gereau RW 4th) Sci Adv 2019 Jul;5(7):eaaw5296 134 Citations |
| 1 | Altered Nuclear Export Signal Recognition as a Driver of Oncogenesis. (Taylor J, Sendino M, Gorelick AN, Pastore A, Chang MT, Penson AV, Gavrila EI, Stewart C, Melnik EM, Herrejon Chavez F, Bitner L, Yoshimi A, Lee SC, Inoue D, Liu B, Zhang XJ, Mato AR, Dogan A, Kharas MG, Chen Y, Wang D, Soni RK, Hendrickson RC, Prieto G, Rodriguez JA, Taylor BS, Abdel-Wahab O) Cancer Discov 2019 Oct;9(10):1452-1467 69 Citations |
| 1 | Extrusion pump ABCC1 was first linked with nonsyndromic hearing loss in humans by stepwise genetic analysis. (Li M, Mei L, He C, Chen H, Cai X, Liu Y, Tian R, Tian Q, Song J, Jiang L, Liu C, Wu H, Li T, Liu J, Li X, Yi Y, Yan D, Blanton SH, Hu Z, Liu X, Li J, Ling J, Feng Y) Genet Med 2019 Dec;21(12):2744-2754 27 Citations |
| 1 | Intracellular Trafficking Network and Autophagy of PHBHHx Nanoparticles and their Implications for Drug Delivery. (Sun X, Cheng C, Zhang J, Jin X, Sun S, Mei L, Huang L) Sci Rep 2019 Jul 03;9(1):9585 13 Citations |
| 1 | Agrin-Lrp4-Ror2 signaling regulates adult hippocampal neurogenesis in mice. (Zhang H, Sathyamurthy A, Liu F, Li L, Zhang L, Dong Z, Cui W, Sun X, Zhao K, Wang H, Ho HH, Xiong WC, Mei L) Elife 2019 Jul 03;8 44 Citations |
| 1 | HPA aptamer functionalized paclitaxel-loaded PLGA nanoparticles for enhanced anticancer therapy through targeted effects and microenvironment modulation. (Duan T, Xu Z, Sun F, Wang Y, Zhang J, Luo C, Wang M) Biomed Pharmacother 2019 Sep;117:109121 58 Citations |
| 1 | Fibrillin-1 in the Vasculature: In Vivo Accumulation of eGFP-Tagged Fibrillin-1 in a Knockin Mouse Model. (Charbonneau NL, Manalo EC, Tufa SF, Carlson EJ, Carlberg VM, Keene DR, Sakai LY) Anat Rec (Hoboken) 2020 Jun;303(6):1590-1603 8 Citations |
| 1 | Potential role of arteether on N-methyl-D-aspartate (NMDA) receptor expression in experimental cerebral malaria mice and extension of their survival. (Singh SK, Dwivedi H, Gunjan S, Chauhan BS, Pandey SK, Tripathi R) Parasitology 2019 Oct;146(12):1571-1577 8 Citations |
| 2 | Gabapentin alleviates chronic spontaneous pain and acute hypoxia-related pain in a mouse model of sickle cell disease. (Sadler KE, Langer SN, Menzel AD, Moehring F, Erb AN, Brandow AM, Stucky CL) Br J Haematol 2019 Oct;187(2):246-260 12 Citations |
| 1 | An innovative in situ method of creating hybrid dendrimer nano-assembly: An efficient next generation dendritic platform for drug delivery. (Singh MK, Kuncha M, Nayak VL, Sarma AVS, Kumar MJM, Chauhan AS, Sistla R) Nanomedicine 2019 Oct;21:102043 29 Citations |
| 3 | The Role of Metabolic Flexibility in the Regulation of the DNA Damage Response by Nitric Oxide. (Oleson BJ, Broniowska KA, Yeo CT, Flancher M, Naatz A, Hogg N, Tarakanova VL, Corbett JA) Mol Cell Biol 2019 Sep 15;39(18) 14 Citations |
| 1 | Dickkopf-1 blocks 17β-estradiol-enhanced object memory consolidation in ovariectomized female mice. (Taxier LR, Philippi SM, Fortress AM, Frick KM) Horm Behav 2019 Aug;114:104545 7 Citations |
| 3 | Osteolytic disease in IL-6 and Myc dependent mouse model of human myeloma. (Sun F, Cheng Y, Walsh SA, Acevedo MR, Jing X, Han SS, Pisano MD, Tomasson MH, Lichtenstein AK, Zhan F, Hari P, Janz S) Haematologica 2020 Mar;105(3):e111-e115 5 Citations |
| 1 | AAV9-mediated delivery of miR-23a reduces disease severity in Smn2B/-SMA model mice. (Kaifer KA, Villalón E, O'Brien BS, Sison SL, Smith CE, Simon ME, Marquez J, O'Day S, Hopkins AE, Neff R, Rindt H, Ebert AD, Lorson CL) Hum Mol Genet 2019 Oct 01;28(19):3199-3210 32 Citations |
| 1 | Borrelia burgdorferi peptidoglycan is a persistent antigen in patients with Lyme arthritis. (Jutras BL, Lochhead RB, Kloos ZA, Biboy J, Strle K, Booth CJ, Govers SK, Gray J, Schumann P, Vollmer W, Bockenstedt LK, Steere AC, Jacobs-Wagner C) Proc Natl Acad Sci U S A 2019 Jul 02;116(27):13498-13507 114 Citations |
| 1 | Radiation and host retinoic acid signaling promote the induction of gut-homing donor T cells after allogeneic hematopoietic stem cell transplantation. (Zheng J, Taylor B, Dodge J, Stephans A, Zheng SG, Chen Q, Chen X) Am J Transplant 2020 Jan;20(1):64-74 3 Citations |
| 1 | An inflammatory pulmonary insult post-traumatic brain injury worsens subsequent spatial learning and neurological outcomes. (Jacovides CL, Ahmed S, Suto Y, Paris AJ, Leone R, McCarry J, Christofidou-Solomidou M, Kaplan LJ, Smith DH, Holena DN, Schwab CW, Pascual JL) J Trauma Acute Care Surg 2019 Sep;87(3):552-558 12 Citations |
| 1 | PARaDIM: A PHITS-Based Monte Carlo Tool for Internal Dosimetry with Tetrahedral Mesh Computational Phantoms. (Carter LM, Crawford TM, Sato T, Furuta T, Choi C, Kim CH, Brown JL, Bolch WE, Zanzonico PB, Lewis JS) J Nucl Med 2019 Dec;60(12):1802-1811 32 Citations |
| 1 | The female reproductive tract contains multiple innate sialic acid-binding immunoglobulin-like lectins (Siglecs) that facilitate sperm survival. (Tecle E, Reynoso HS, Wang R, Gagneux P) J Biol Chem 2019 Aug 02;294(31):11910-11919 34 Citations |
| 3 | Hepatic pathology and altered gene transcription in a murine model of acid ceramidase deficiency. (Yu FPS, Molino S, Sikora J, Rasmussen S, Rybova J, Tate E, Geurts AM, Turner PV, Mckillop WM, Medin JA) Lab Invest 2019 Oct;99(10):1572-1592 14 Citations |
| 1 | Presynaptic Expression of LRIT3 Transsynaptically Organizes the Postsynaptic Glutamate Signaling Complex Containing TRPM1. (Hasan N, Pangeni G, Cobb CA, Ray TA, Nettesheim ER, Ertel KJ, Lipinski DM, McCall MA, Gregg RG) Cell Rep 2019 Jun 11;27(11):3107-3116.e3 35 Citations |
| 1 | Conditional deletion of smooth muscle Cullin-3 causes severe progressive hypertension. (Agbor LN, Nair AR, Wu J, Lu KT, Davis DR, Keen HL, Quelle FW, McCormick JA, Singer JD, Sigmund CD) JCI Insight 2019 Jun 11;5(14) 26 Citations |
| 1 | RASA1-dependent cellular export of collagen IV controls blood and lymphatic vascular development. (Chen D, Teng JM, North PE, Lapinski PE, King PD) J Clin Invest 2019 Jun 11;129(9):3545-3561 48 Citations |
| 1 | Microglia in the Primary Somatosensory Barrel Cortex Mediate Trigeminal Neuropathic Pain. (Wang Y, Cao P, Mei L, Yin W, Mao Y, Niu C, Zhang Z, Tao W) Neuroscience 2019 Aug 21;414:299-310 14 Citations |
| 1 | Estrogen therapy induces an unfolded protein response to drive cell death in ER+ breast cancer. (Hosford SR, Shee K, Wells JD, Traphagen NA, Fields JL, Hampsch RA, Kettenbach AN, Demidenko E, Miller TW) Mol Oncol 2019 Aug;13(8):1778-1794 17 Citations |
| 1 | The BBSome in POMC and AgRP Neurons Is Necessary for Body Weight Regulation and Sorting of Metabolic Receptors. (Guo DF, Lin Z, Wu Y, Searby C, Thedens DR, Richerson GB, Usachev YM, Grobe JL, Sheffield VC, Rahmouni K) Diabetes 2019 Aug;68(8):1591-1603 39 Citations |
| 1 | Two Distinct E2F Transcriptional Modules Drive Cell Cycles and Differentiation. (Cuitiño MC, Pécot T, Sun D, Kladney R, Okano-Uchida T, Shinde N, Saeed R, Perez-Castro AJ, Webb A, Liu T, Bae SI, Clijsters L, Selner N, Coppola V, Timmers C, Ostrowski MC, Pagano M, Leone G) Cell Rep 2019 Jun 18;27(12):3547-3560.e5 44 Citations |
| 1 | Diacylglycerol Lipase-Alpha Regulates Hippocampal-Dependent Learning and Memory Processes in Mice. (Schurman LD, Carper MC, Moncayo LV, Ogasawara D, Richardson K, Yu L, Liu X, Poklis JL, Liu QS, Cravatt BF, Lichtman AH) J Neurosci 2019 Jul 24;39(30):5949-5965 18 Citations |
| 4 | Aurora kinase B-phosphorylated HP1α functions in chromosomal instability. (Williams MM, Mathison AJ, Christensen T, Greipp PT, Knutson DL, Klee EW, Zimmermann MT, Iovanna J, Lomberk GA, Urrutia RA) Cell Cycle 2019 Jun;18(12):1407-1421 9 Citations |
| 1 | pHluorin-BACE1-mCherry Acts as a Reporter for the Intracellular Distribution of Active BACE1 In Vitro and In Vivo. (Zhao L, Zhao Y, Tang FL, Xiong L, Su C, Mei L, Zhu XJ, Xiong WC) Cells 2019 May 17;8(5) 10 Citations |
| 4 | Targeting lonidamine to mitochondria mitigates lung tumorigenesis and brain metastasis. (Cheng G, Zhang Q, Pan J, Lee Y, Ouari O, Hardy M, Zielonka M, Myers CR, Zielonka J, Weh K, Chang AC, Chen G, Kresty L, Kalyanaraman B, You M) Nat Commun 2019 May 17;10(1):2205 181 Citations |
| 2 | CBX5/G9a/H3K9me-mediated gene repression is essential to fibroblast activation during lung fibrosis. (Ligresti G, Caporarello N, Meridew JA, Jones DL, Tan Q, Choi KM, Haak AJ, Aravamudhan A, Roden AC, Prakash YS, Lomberk G, Urrutia RA, Tschumperlin DJ) JCI Insight 2019 May 16;5(12) 63 Citations |
| 1 | Dickkopf-1 Treatment Stimulates Hematopoietic Regenerative Function in Infused Endothelial Progenitor Cells. (Kim MM, Schlussel L, Zhao L, Himburg HA) Radiat Res 2019 Jul;192(1):53-62 10 Citations |
| 4 | Critical role of Jumonji domain of JMJD1C in MLL-rearranged leukemia. (Izaguirre-Carbonell J, Christiansen L, Burns R, Schmitz J, Li C, Mokry RL, Bluemn T, Zheng Y, Shen J, Carlson KS, Rao S, Wang D, Zhu N) Blood Adv 2019 May 14;3(9):1499-1511 21 Citations |
| 1 | Proteasomal Degradation of Enhancer of Zeste Homologue 2 in Cholangiocytes Promotes Biliary Fibrosis. (Jalan-Sakrikar N, De Assuncao TM, Shi G, Aseem SO, Chi C, Shah VH, Huebert RC) Hepatology 2019 Nov;70(5):1674-1689 22 Citations |
| 1 | Attenuation of cardiac ischemia-reperfusion injury by sodium thiosulfate is partially dependent on the effect of cystathione beta synthase in the myocardium. (Kannan S, Boovarahan SR, Rengaraju J, Prem P, Kurian GA) Cell Biochem Biophys 2019 Sep;77(3):261-272 17 Citations |
| 1 | Characterization of a KLK2-FGFR2 fusion gene in two cases of metastatic prostate cancer. (Krook MA, Barker H, Chen HZ, Reeser JW, Wing MR, Martin D, Smith AM, Dao T, Bonneville R, Samorodnitsky E, Miya J, Freud AG, Monk JP, Clinton SK, Roychowdhury S) Prostate Cancer Prostatic Dis 2019 Dec;22(4):624-632 7 Citations |
| 1 | Thioredoxin-1 confines T cell alloresponse and pathogenicity in graft-versus-host disease. (Sofi MH, Wu Y, Schutt SD, Dai M, Daenthanasanmak A, Heinrichs Voss J, Nguyen H, Bastian D, Iamsawat S, Selvam SP, Liu C, Maulik N, Ogretmen B, Jin J, Mehrotra S, Yu XZ) J Clin Invest 2019 May 02;129(7):2760-2774 32 Citations |
| 1 | Blocking COX-2 for sickle cell pain relief. (Sadler KE, Stucky CL) Blood 2019 May 02;133(18):1924-1925 4 Citations |
| 1 | TMEM33 regulates intracellular calcium homeostasis in renal tubular epithelial cells. (Arhatte M, Gunaratne GS, El Boustany C, Kuo IY, Moro C, Duprat F, Plaisant M, Duval H, Li D, Picard N, Couvreux A, Duranton C, Rubera I, Pagnotta S, Lacas-Gervais S, Ehrlich BE, Marchant JS, Savage AM, van Eeden FJM, Wilkinson RN, Demolombe S, Honoré E, Patel A) Nat Commun 2019 May 02;10(1):2024 19 Citations |
| 3 | STING agonist inflames the pancreatic cancer immune microenvironment and reduces tumor burden in mouse models. (Jing W, McAllister D, Vonderhaar EP, Palen K, Riese MJ, Gershan J, Johnson BD, Dwinell MB) J Immunother Cancer 2019 Apr 29;7(1):115 142 Citations |
| 1 | The bispecific antibody HB-32, blockade of both VEGF and DLL4 shows potent anti-angiogenic activity in vitro and anti-tumor activity in breast cancer xenograft models. (Zhou R, Wang S, Wen H, Wang M, Wu M) Exp Cell Res 2019 Jul 15;380(2):141-148 17 Citations |
| 1 | In vivo selective inhibition of TRPC6 by antagonist BI 749327 ameliorates fibrosis and dysfunction in cardiac and renal disease. (Lin BL, Matera D, Doerner JF, Zheng N, Del Camino D, Mishra S, Bian H, Zeveleva S, Zhen X, Blair NT, Chong JA, Hessler DP, Bedja D, Zhu G, Muller GK, Ranek MJ, Pantages L, McFarland M, Netherton MR, Berry A, Wong D, Rast G, Qian HS, Weldon SM, Kuo JJ, Sauer A, Sarko C, Moran MM, Kass DA, Pullen SS) Proc Natl Acad Sci U S A 2019 May 14;116(20):10156-10161 104 Citations |
| 1 | Mechanistic Target of Rapamycin Complex 1 Signaling Modulates Vascular Endothelial Function Through Reactive Oxygen Species. (Reho JJ, Guo DF, Rahmouni K) J Am Heart Assoc 2019 May 07;8(9):e010662 27 Citations |
| 1 | Gut microbiome-derived phenyl sulfate contributes to albuminuria in diabetic kidney disease. (Kikuchi K, Saigusa D, Kanemitsu Y, Matsumoto Y, Thanai P, Suzuki N, Mise K, Yamaguchi H, Nakamura T, Asaji K, Mukawa C, Tsukamoto H, Sato T, Oikawa Y, Iwasaki T, Oe Y, Tsukimi T, Fukuda NN, Ho HJ, Nanto-Hara F, Ogura J, Saito R, Nagao S, Ohsaki Y, Shimada S, Suzuki T, Toyohara T, Mishima E, Shima H, Akiyama Y, Akiyama Y, Ichijo M, Matsuhashi T, Matsuo A, Ogata Y, Yang CC, Suzuki C, Breeggemann MC, Heymann J, Shimizu M, Ogawa S, Takahashi N, Suzuki T, Owada Y, Kure S, Mano N, Soga T, Wada T, Kopp JB, Fukuda S, Hozawa A, Yamamoto M, Ito S, Wada J, Tomioka Y, Abe T) Nat Commun 2019 Apr 23;10(1):1835 237 Citations |
| 2 | Chemogenetic Suppression of Medial Prefrontal-Dorsal Hippocampal Interactions Prevents Estrogenic Enhancement of Memory Consolidation in Female Mice. (Tuscher JJ, Taxier LR, Schalk JC, Haertel JM, Frick KM) eNeuro 2019;6(2) 21 Citations |
| 1 | Targeting LIF-mediated paracrine interaction for pancreatic cancer therapy and monitoring. (Shi Y, Gao W, Lytle NK, Huang P, Yuan X, Dann AM, Ridinger-Saison M, DelGiorno KE, Antal CE, Liang G, Atkins AR, Erikson G, Sun H, Meisenhelder J, Terenziani E, Woo G, Fang L, Santisakultarm TP, Manor U, Xu R, Becerra CR, Borazanci E, Von Hoff DD, Grandgenett PM, Hollingsworth MA, Leblanc M, Umetsu SE, Collisson EA, Scadeng M, Lowy AM, Donahue TR, Reya T, Downes M, Evans RM, Wahl GM, Pawson T, Tian R, Hunter T) Nature 2019 May;569(7754):131-135 324 Citations |
| 1 | Administration of dexamethasone disrupts endometrial receptivity by alteration of expression of miRNA 223, 200a, LIF, Muc1, SGK1, and ENaC via the ERK1/2-mTOR pathway. (Shariati MBH, Niknafs B, Seghinsara AM, Shokrzadeh N, Alivand MR) J Cell Physiol 2019 Nov;234(11):19629-19639 25 Citations |
| 1 | Sex-specific regulation of stress-induced fetal glucocorticoid surge by the mouse placenta. (Wieczorek A, Perani CV, Nixon M, Constancia M, Sandovici I, Zazara DE, Leone G, Zhang MZ, Arck PC, Solano ME) Am J Physiol Endocrinol Metab 2019 Jul 01;317(1):E109-E120 40 Citations |
| 1 | NIR-Light-Activated Combination Therapy with a Precise Ratio of Photosensitizer and Prodrug Using a Host-Guest Strategy. (Chen H, Zeng X, Tham HP, Phua SZF, Cheng W, Zeng W, Shi H, Mei L, Zhao Y) Angew Chem Int Ed Engl 2019 Jun 03;58(23):7641-7646 149 Citations |
| 1 | Thioredoxin-1 improves the immunometabolic phenotype of antitumor T cells. (Chakraborty P, Chatterjee S, Kesarwani P, Thyagarajan K, Iamsawat S, Dalheim A, Nguyen H, Selvam SP, Nasarre P, Scurti G, Hardiman G, Maulik N, Ball L, Gangaraju V, Rubinstein MP, Klauber-DeMore N, Hill EG, Ogretmen B, Yu XZ, Nishimura MI, Mehrotra S) J Biol Chem 2019 Jun 07;294(23):9198-9212 32 Citations |
| 2 | Diacylglycerol kinase ζ is a negative regulator of GPVI-mediated platelet activation. (Moroi AJ, Zwifelhofer NM, Riese MJ, Newman DK, Newman PJ) Blood Adv 2019 Apr 09;3(7):1154-1166 8 Citations |
| 1 | A Multiscale Map of the Stem Cell State in Pancreatic Adenocarcinoma. (Lytle NK, Ferguson LP, Rajbhandari N, Gilroy K, Fox RG, Deshpande A, Schürch CM, Hamilton M, Robertson N, Lin W, Noel P, Wartenberg M, Zlobec I, Eichmann M, Galván JA, Karamitopoulou E, Gilderman T, Esparza LA, Shima Y, Spahn P, French R, Lewis NE, Fisch KM, Sasik R, Rosenthal SB, Kritzik M, Von Hoff D, Han H, Ideker T, Deshpande AJ, Lowy AM, Adams PD, Reya T) Cell 2019 Apr 18;177(3):572-586.e22 113 Citations |
| 1 | Trefoil factor(s) and CA19.9: A promising panel for early detection of pancreatic cancer. (Jahan R, Ganguly K, Smith LM, Atri P, Carmicheal J, Sheinin Y, Rachagani S, Natarajan G, Brand RE, Macha MA, Grandgenett PM, Kaur S, Batra SK) EBioMedicine 2019 Apr;42:375-385 36 Citations |
| 1 | Preventive Effects by Black Raspberries of Endometrial Carcinoma Initiation and Promotion Induced by a High-Fat Diet. (Huang YW, Chen JH, Rader JS, Aguilera-Barrantes I, Wang LS) Mol Nutr Food Res 2019 Jun;63(12):e1900013 2 Citations |
| 2 | Comparison of the Effects of High-Fat Diet on Energy Flux in Mice Using Two Multiplexed Metabolic Phenotyping Systems. (Soto JE, Burnett CML, Ten Eyck P, Abel ED, Grobe JL) Obesity (Silver Spring) 2019 May;27(5):793-802 24 Citations |
| 1 | Gab2 and Gab3 Redundantly Suppress Colitis by Modulating Macrophage and CD8+ T-Cell Activation. (Wang Z, Vaughan TY, Zhu W, Chen Y, Fu G, Medrzycki M, Nishio H, Bunting ST, Hankey-Giblin PA, Nusrat A, Parkos CA, Wang D, Wen R, Bunting KD) Front Immunol 2019;10:486 13 Citations |
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| 1 | Anti-CD24 Antibody-Nitric Oxide Conjugate Selectively and Potently Suppresses Hepatic Carcinoma. (Sun F, Wang Y, Luo X, Ma Z, Xu Y, Zhang X, Lv T, Zhang Y, Wang M, Huang Z, Zhang J) Cancer Res 2019 Jul 01;79(13):3395-3405 51 Citations |
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| 1 | Pharmacokinetics and efficacy of orally administered polymeric chloroquine as macromolecular drug in the treatment of inflammatory bowel disease. (Kanvinde S, Chhonker YS, Ahmad R, Yu F, Sleightholm R, Tang W, Jaramillo L, Chen Y, Sheinin Y, Li J, Murry DJ, Singh AB, Oupický D) Acta Biomater 2018 Dec;82:158-170 20 Citations |
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| 1 | FABP4 as a key determinant of metastatic potential of ovarian cancer. (Gharpure KM, Pradeep S, Sans M, Rupaimoole R, Ivan C, Wu SY, Bayraktar E, Nagaraja AS, Mangala LS, Zhang X, Haemmerle M, Hu W, Rodriguez-Aguayo C, McGuire M, Mak CSL, Chen X, Tran MA, Villar-Prados A, Pena GA, Kondetimmanahalli R, Nini R, Koppula P, Ram P, Liu J, Lopez-Berestein G, Baggerly K, S Eberlin L, Sood AK) Nat Commun 2018 Jul 26;9(1):2923 174 Citations |
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| 2 | Crosstalk between PKCα and PI3K/AKT Signaling Is Tumor Suppressive in the Endometrium. (Hsu AH, Lum MA, Shim KS, Frederick PJ, Morrison CD, Chen B, Lele SM, Sheinin YM, Daikoku T, Dey SK, Leone G, Black AR, Black JD) Cell Rep 2018 Jul 17;24(3):655-669 38 Citations |
| 1 | Glyceraldehyde-3-phosphate dehydrogenase is a chaperone that allocates labile heme in cells. (Sweeny EA, Singh AB, Chakravarti R, Martinez-Guzman O, Saini A, Haque MM, Garee G, Dans PD, Hannibal L, Reddi AR, Stuehr DJ) J Biol Chem 2018 Sep 14;293(37):14557-14568 90 Citations |
| 1 | Noncanonical translation via deadenylated 3' UTRs maintains primordial germ cells. (Jin YN, Schlueter PJ, Jurisch-Yaksi N, Lam PY, Jin S, Hwang WY, Yeh JJ, Yoshigi M, Ong SE, Schenone M, Hartigan CR, Carr SA, Peterson RT) Nat Chem Biol 2018 Sep;14(9):844-852 8 Citations |
| 1 | Use Of Ankle Immobilization In Evaluating Treatments To Promote Longitudinal Muscle Growth In Mice. (Tinklenberg J, Beatka M, Bain JLW, Siebers EM, Meng H, Pearsall RS, Lawlor MW, Riley DA) Muscle Nerve 2018 Nov;58(5):718-725 6 Citations |
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| 1 | Role for fatty acid amide hydrolase (FAAH) in the leptin-mediated effects on feeding and energy balance. (Balsevich G, Sticht M, Bowles NP, Singh A, Lee TTY, Li Z, Chelikani PK, Lee FS, Borgland SL, Hillard CJ, McEwen BS, Hill MN) Proc Natl Acad Sci U S A 2018 Jul 17;115(29):7605-7610 33 Citations |
| 1 | Sympathetic Neuronal Activation Triggers Myeloid Progenitor Proliferation and Differentiation. (Vasamsetti SB, Florentin J, Coppin E, Stiekema LCA, Zheng KH, Nisar MU, Sembrat J, Levinthal DJ, Rojas M, Stroes ESG, Kim K, Dutta P) Immunity 2018 Jul 17;49(1):93-106.e7 92 Citations |
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| 1 | A novel combined ex vivo and in vivo lentiviral interleukin-10 gene delivery strategy at the time of transplantation decreases chronic lung allograft rejection in mice. (Oishi H, Juvet SC, Martinu T, Sato M, Medin JA, Liu M, Keshavjee S) J Thorac Cardiovasc Surg 2018 Sep;156(3):1305-1315 20 Citations |
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| 1 | Optogenetic Inhibition of CGRPα Sensory Neurons Reveals Their Distinct Roles in Neuropathic and Incisional Pain. (Cowie AM, Moehring F, O'Hara C, Stucky CL) J Neurosci 2018 Jun 20;38(25):5807-5825 55 Citations |
| 1 | Quantitative Top-Down Mass Spectrometry Identifies Proteoforms Differentially Released during Mechanical Stimulation of Mouse Skin. (Moehring F, Waas M, Keppel TR, Rathore D, Cowie AM, Stucky CL, Gundry RL) J Proteome Res 2018 Aug 03;17(8):2635-2648 6 Citations |
| 2 | IQ Domain-Containing GTPase-Activating Protein 1 Regulates Cytoskeletal Reorganization and Facilitates NKG2D-Mediated Mechanistic Target of Rapamycin Complex 1 Activation and Cytokine Gene Translation in Natural Killer Cells. (Abel AM, Tiwari AA, Gerbec ZJ, Siebert JR, Yang C, Schloemer NJ, Dixon KJ, Thakar MS, Malarkannan S) Front Immunol 2018;9:1168 15 Citations |
| 1 | The Lateral Habenula Directs Coping Styles Under Conditions of Stress via Recruitment of the Endocannabinoid System. (Berger AL, Henricks AM, Lugo JM, Wright HR, Warrick CR, Sticht MA, Morena M, Bonilla I, Laredo SA, Craft RM, Parsons LH, Grandes PR, Hillard CJ, Hill MN, McLaughlin RJ) Biol Psychiatry 2018 Oct 15;84(8):611-623 45 Citations |
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| 2 | A NOX4/TRPC6 Pathway in Podocyte Calcium Regulation and Renal Damage in Diabetic Kidney Disease. (Ilatovskaya DV, Blass G, Palygin O, Levchenko V, Pavlov TS, Grzybowski MN, Winsor K, Shuyskiy LS, Geurts AM, Cowley AW Jr, Birnbaumer L, Staruschenko A) J Am Soc Nephrol 2018 Jul;29(7):1917-1927 113 Citations |
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| 1 | Endothelial PPARγ (Peroxisome Proliferator-Activated Receptor-γ) Is Essential for Preventing Endothelial Dysfunction With Aging. (De Silva TM, Li Y, Kinzenbaw DA, Sigmund CD, Faraci FM) Hypertension 2018 Jul;72(1):227-234 32 Citations |
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| 1 | Engineering vascularized skeletal muscle tissue with transcriptional factor ETV2-induced autologous endothelial cells. (Yan G, Yan R, Chen C, Chen C, Zhao Y, Qin W, Veldman MB, Li S, Lin S) Protein Cell 2019 Mar;10(3):217-222 9 Citations |
| 1 | Cytokine-Producing B Cells Promote Immune-Mediated Bile Duct Injury in Murine Biliary Atresia. (Bednarek J, Traxinger B, Brigham D, Roach J, Orlicky D, Wang D, Pelanda R, Mack CL) Hepatology 2018 Nov;68(5):1890-1904 32 Citations |
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| 1 | Metabotropic Glutamate Receptor 2/3 (mGluR2/3) Activation Suppresses TRPV1 Sensitization in Mouse, But Not Human, Sensory Neurons. (Sheahan TD, Valtcheva MV, McIlvried LA, Pullen MY, Baranger DAA, Gereau RW 4th) eNeuro 2018;5(2) 33 Citations |
| 1 | Airway glycomic and allergic inflammatory consequences resulting from keratan sulfate galactose 6-O-sulfotransferase (CHST1) deficiency. (Kumagai T, Kiwamoto T, Brummet ME, Wu F, Aoki K, Zhu Z, Bochner BS, Tiemeyer M) Glycobiology 2018 Jun 01;28(6):406-417 13 Citations |
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| 1 | Inflammatory Macrophage Expansion in Pulmonary Hypertension Depends upon Mobilization of Blood-Borne Monocytes. (Florentin J, Coppin E, Vasamsetti SB, Zhao J, Tai YY, Tang Y, Zhang Y, Watson A, Sembrat J, Rojas M, Vargas SO, Chan SY, Dutta P) J Immunol 2018 May 15;200(10):3612-3625 118 Citations |
| 1 | Intratibial Injection Causes Direct Pulmonary Seeding of Osteosarcoma Cells and Is Not a Spontaneous Model of Metastasis: A Mouse Osteosarcoma Model. (Maloney C, Edelman MC, Kallis MP, Soffer SZ, Symons M, Steinberg BM) Clin Orthop Relat Res 2018 Jul;476(7):1514-1522 26 Citations |
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| 1 | The membrane-distal regions of integrin α cytoplasmic domains contribute differently to integrin inside-out activation. (Thinn AMM, Wang Z, Zhu J) Sci Rep 2018 Mar 22;8(1):5067 10 Citations |
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| 1 | Intravenous administration of synthetic platelets (SynthoPlate) in a mouse liver injury model of uncontrolled hemorrhage improves hemostasis. (Dyer MR, Hickman D, Luc N, Haldeman S, Loughran P, Pawlowski C, Sen Gupta A, Neal MD) J Trauma Acute Care Surg 2018 Jun;84(6):917-923 39 Citations |
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| 1 | NKG2D Immunoligand rG7S-MICA Enhances NK Cell-mediated Immunosurveillance in Colorectal Carcinoma. (Wang T, Sun F, Wang Y, Jiang J, Pan M, Yuan M, Zhang H, Du X, Hezam K, Song K, Wang M, Zhang J) J Immunother 2018 Apr;41(3):109-117 14 Citations |
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| 1 | Csk/CD148 and platelet SFK activation: a balancing act! (Zhu J) Blood 2018 Mar 08;131(10):1042-1043 5 Citations |
| 2 | Comparative and integrative metabolomics reveal that S-nitrosation inhibits physiologically relevant metabolic enzymes. (Bruegger JJ, Smith BC, Wynia-Smith SL, Marletta MA) J Biol Chem 2018 Apr 27;293(17):6282-6296 15 Citations |
| 1 | STAT5A/B Blockade Sensitizes Prostate Cancer to Radiation through Inhibition of RAD51 and DNA Repair. (Maranto C, Udhane V, Hoang DT, Gu L, Alexeev V, Malas K, Cardenas K, Brody JR, Rodeck U, Bergom C, Iczkowski KA, Jacobsohn K, See W, Schmitt SM, Nevalainen MT) Clin Cancer Res 2018 Apr 15;24(8):1917-1931 44 Citations |
| 1 | Inhibition of the IRE-1α/XBP-1 pathway prevents chronic GVHD and preserves the GVL effect in mice. (Schutt SD, Wu Y, Tang CH, Bastian D, Nguyen H, Sofi MH, Zhang M, Liu C, Helke K, Wilson C, Schnapp LM, Del Valle JR, Hu CC, Yu XZ) Blood Adv 2018 Feb 27;2(4):414-427 21 Citations |
| 2 | Design and Synthesis of Novel Deuterated Ligands Functionally Selective for the γ-Aminobutyric Acid Type A Receptor (GABAAR) α6 Subtype with Improved Metabolic Stability and Enhanced Bioavailability. (Knutson DE, Kodali R, Divović B, Treven M, Stephen MR, Zahn NM, Dobričić V, Huber AT, Meirelles MA, Verma RS, Wimmer L, Witzigmann C, Arnold LA, Chiou LC, Ernst M, Mihovilovic MD, Savić MM, Sieghart W, Cook JM) J Med Chem 2018 Mar 22;61(6):2422-2446 39 Citations |
| 2 | Characterization of Coding/Noncoding Variants for SHROOM3 in Patients with CKD. (Prokop JW, Yeo NC, Ottmann C, Chhetri SB, Florus KL, Ross EJ, Sosonkina N, Link BA, Freedman BI, Coppola CJ, McDermott-Roe C, Leysen S, Milroy LG, Meijer FA, Geurts AM, Rauscher FJ 3rd, Ramaker R, Flister MJ, Jacob HJ, Mendenhall EM, Lazar J) J Am Soc Nephrol 2018 May;29(5):1525-1535 38 Citations |
| 1 | Improved Murine MHC-Deficient HLA Transgenic NOD Mouse Models for Type 1 Diabetes Therapy Development. (Racine JJ, Stewart I, Ratiu J, Christianson G, Lowell E, Helm K, Allocco J, Maser RS, Chen YG, Lutz CM, Roopenian D, Schloss J, DiLorenzo TP, Serreze DV) Diabetes 2018 May;67(5):923-935 16 Citations |
| 2 | Deactivation of 12(S)-HETE through (ω-1)-hydroxylation and β-oxidation in alternatively activated macrophages. (Kriska T, Thomas MJ, Falck JR, Campbell WB) J Lipid Res 2018 Apr;59(4):615-624 7 Citations |
| 1 | P300 Acetyltransferase Mediates Stiffness-Induced Activation of Hepatic Stellate Cells Into Tumor-Promoting Myofibroblasts. (Dou C, Liu Z, Tu K, Zhang H, Chen C, Yaqoob U, Wang Y, Wen J, van Deursen J, Sicard D, Tschumperlin D, Zou H, Huang WC, Urrutia R, Shah VH, Kang N) Gastroenterology 2018 Jun;154(8):2209-2221.e14 171 Citations |
| 1 | Intravenous synthetic platelet (SynthoPlate) nanoconstructs reduce bleeding and improve 'golden hour' survival in a porcine model of traumatic arterial hemorrhage. (Hickman DA, Pawlowski CL, Shevitz A, Luc NF, Kim A, Girish A, Marks J, Ganjoo S, Huang S, Niedoba E, Sekhon UDS, Sun M, Dyer M, Neal MD, Kashyap VS, Sen Gupta A) Sci Rep 2018 Feb 15;8(1):3118 68 Citations |
| 1 | Cutting Edge: Check Your Mice-A Point Mutation in the Ncr1 Locus Identified in CD45.1 Congenic Mice with Consequences in Mouse Susceptibility to Infection. (Jang Y, Gerbec ZJ, Won T, Choi B, Podsiad A, B Moore B, Malarkannan S, Laouar Y) J Immunol 2018 Mar 15;200(6):1982-1987 25 Citations |
| 1 | Therapeutically targeting tumor microenvironment-mediated drug resistance in estrogen receptor-positive breast cancer. (Shee K, Yang W, Hinds JW, Hampsch RA, Varn FS, Traphagen NA, Patel K, Cheng C, Jenkins NP, Kettenbach AN, Demidenko E, Owens P, Faber AC, Golub TR, Straussman R, Miller TW) J Exp Med 2018 Mar 05;215(3):895-910 63 Citations |
| 1 | The NLRP3 Inflammasome May Contribute to Pathologic Neovascularization in the Advanced Stages of Diabetic Retinopathy. (Chaurasia SS, Lim RR, Parikh BH, Wey YS, Tun BB, Wong TY, Luu CD, Agrawal R, Ghosh A, Mortellaro A, Rackoczy E, Mohan RR, Barathi VA) Sci Rep 2018 Feb 12;8(1):2847 126 Citations |
| 1 | TP53 Haploinsufficiency Rescues Emergency Granulopoiesis in FANCC-/- Mice. (Hu L, Huang W, Bei L, Broglie L, Eklund EA) J Immunol 2018 Mar 15;200(6):2129-2139 6 Citations |
| 1 | Intravenous Administration of a MTMR2-Encoding AAV Vector Ameliorates the Phenotype of Myotubular Myopathy in Mice. (Danièle N, Moal C, Julien L, Marinello M, Jamet T, Martin S, Vignaud A, Lawlor MW, Buj-Bello A) J Neuropathol Exp Neurol 2018 Apr 01;77(4):282-295 16 Citations |
| 1 | Tuning microtubule dynamics to enhance cancer therapy by modulating FER-mediated CRMP2 phosphorylation. (Zheng Y, Sethi R, Mangala LS, Taylor C, Goldsmith J, Wang M, Masuda K, Carrami EM, Mannion D, Miranda F, Herrero-Gonzalez S, Hellner K, Chen F, Alsaadi A, Albukhari A, Fotso DC, Yau C, Jiang D, Pradeep S, Rodriguez-Aguayo C, Lopez-Berestein G, Knapp S, Gray NS, Campo L, Myers KA, Dhar S, Ferguson D, Bast RC Jr, Sood AK, von Delft F, Ahmed AA) Nat Commun 2018 Feb 02;9(1):476 39 Citations |
| 1 | Deep vein thrombosis in mice is regulated by platelet HMGB1 through release of neutrophil-extracellular traps and DNA. (Dyer MR, Chen Q, Haldeman S, Yazdani H, Hoffman R, Loughran P, Tsung A, Zuckerbraun BS, Simmons RL, Neal MD) Sci Rep 2018 Feb 01;8(1):2068 144 Citations |
| 1 | Stat3 and CCAAT enhancer-binding protein β (C/ebpβ) activate Fanconi C gene transcription during emergency granulopoiesis. (Shah CA, Broglie L, Hu L, Bei L, Huang W, Dressler DB, Eklund EA) J Biol Chem 2018 Mar 16;293(11):3937-3948 8 Citations |
| 1 | Targeting JAK2 reduces GVHD and xenograft rejection through regulation of T cell differentiation. (Betts BC, Bastian D, Iamsawat S, Nguyen H, Heinrichs JL, Wu Y, Daenthanasanmak A, Veerapathran A, O'Mahony A, Walton K, Reff J, Horna P, Sagatys EM, Lee MC, Singer J, Chang YJ, Liu C, Pidala J, Anasetti C, Yu XZ) Proc Natl Acad Sci U S A 2018 Feb 13;115(7):1582-1587 62 Citations |
| 1 | Deletion of MCP-1 Impedes Pathogenesis of Acid Ceramidase Deficiency. (Yu FPS, Dworski S, Medin JA) Sci Rep 2018 Jan 29;8(1):1808 18 Citations |
| 1 | Negative allosteric modulation of alpha 5-containing GABAA receptors engenders antidepressant-like effects and selectively prevents age-associated hyperactivity in tau-depositing mice. (Xu NZ, Ernst M, Treven M, Cerne R, Wakulchik M, Li X, Jones TM, Gleason SD, Morrow D, Schkeryantz JM, Rahman MT, Li G, Poe MM, Cook JM, Witkin JM) Psychopharmacology (Berl) 2018 Apr;235(4):1151-1161 19 Citations |
| 2 | Angiotensin AT1A receptors expressed in vasopressin-producing cells of the supraoptic nucleus contribute to osmotic control of vasopressin. (Sandgren JA, Linggonegoro DW, Zhang SY, Sapouckey SA, Claflin KE, Pearson NA, Leidinger MR, Pierce GL, Santillan MK, Gibson-Corley KN, Sigmund CD, Grobe JL) Am J Physiol Regul Integr Comp Physiol 2018 Jun 01;314(6):R770-R780 34 Citations |
| 1 | Ac-SDKP decreases mortality and cardiac rupture after acute myocardial infarction. (Nakagawa P, Romero CA, Jiang X, D'Ambrosio M, Bordcoch G, Peterson EL, Harding P, Yang XP, Carretero OA) PLoS One 2018;13(1):e0190300 16 Citations |
| 2 | Dextran Enhances the Lentiviral Transduction Efficiency of Murine and Human Primary NK Cells. (Nanbakhsh A, Best B, Riese M, Rao S, Wang L, Medin J, Thakar MS, Malarkannan S) J Vis Exp 2018 Jan 15(131) 15 Citations |
| 1 | Phosphorylation of EZH2 by AMPK Suppresses PRC2 Methyltransferase Activity and Oncogenic Function. (Wan L, Xu K, Wei Y, Zhang J, Han T, Fry C, Zhang Z, Wang YV, Huang L, Yuan M, Xia W, Chang WC, Huang WC, Liu CL, Chang YC, Liu J, Wu Y, Jin VX, Dai X, Guo J, Liu J, Jiang S, Li J, Asara JM, Brown M, Hung MC, Wei W) Mol Cell 2018 Jan 18;69(2):279-291.e5 148 Citations |
| 1 | PAR1 agonists stimulate APC-like endothelial cytoprotection and confer resistance to thromboinflammatory injury. (De Ceunynck K, Peters CG, Jain A, Higgins SJ, Aisiku O, Fitch-Tewfik JL, Chaudhry SA, Dockendorff C, Parikh SM, Ingber DE, Flaumenhaft R) Proc Natl Acad Sci U S A 2018 Jan 30;115(5):E982-E991 59 Citations |
| 1 | Targeted knockout of a chemokine-like gene increases anxiety and fear responses. (Choi JH, Jeong YM, Kim S, Lee B, Ariyasiri K, Kim HT, Jung SH, Hwang KS, Choi TI, Park CO, Huh WK, Carl M, Rosenfeld JA, Raskin S, Ma A, Gecz J, Kim HG, Kim JS, Shin HC, Park DS, Gerlai R, Jamieson BB, Kim JS, Iremonger KJ, Lee SH, Shin HS, Kim CH) Proc Natl Acad Sci U S A 2018 Jan 30;115(5):E1041-E1050 40 Citations |
| 1 | Beta-catenin cleavage enhances transcriptional activation. (Goretsky T, Bradford EM, Ye Q, Lamping OF, Vanagunas T, Moyer MP, Keller PC, Sinh P, Llovet JM, Gao T, She QB, Li L, Barrett TA) Sci Rep 2018 Jan 12;8(1):671 25 Citations |
| 1 | Enhancing toxin-based vaccines against botulism. (Przedpelski A, Tepp WH, Zuverink M, Johnson EA, Pellet S, Barbieri JT) Vaccine 2018 Feb 01;36(6):827-832 25 Citations |
| 1 | Myostatin inhibition using mRK35 produces skeletal muscle growth and tubular aggregate formation in wild type and TgACTA1D286G nemaline myopathy mice. (Tinklenberg JA, Siebers EM, Beatka MJ, Meng H, Yang L, Zhang Z, Ross JA, Ochala J, Morris C, Owens JM, Laing NG, Nowak KJ, Lawlor MW) Hum Mol Genet 2018 Feb 15;27(4):638-648 28 Citations |
| 1 | Protonation state of glutamate 73 regulates the formation of a specific dimeric association of mVDAC1. (Bergdoll LA, Lerch MT, Patrick JW, Belardo K, Altenbach C, Bisignano P, Laganowsky A, Grabe M, Hubbell WL, Abramson J) Proc Natl Acad Sci U S A 2018 Jan 09;115(2):E172-E179 33 Citations |
| 1 | Cysteinyl leukotriene receptor 1 expression identifies a subset of neutrophils during the antiviral response that contributes to postviral atopic airway disease. (Cheung DS, Sigua JA, Simpson PM, Yan K, Hussain SA, Santoro JL, Buell EJ, Hunter DA, Rohlfing M, Patadia D, Grayson MH) J Allergy Clin Immunol 2018 Oct;142(4):1206-1217.e5 27 Citations |
| 1 | The Effect of Topoisomerase I Inhibitors on the Efficacy of T-Cell-Based Cancer Immunotherapy. (McKenzie JA, Mbofung RM, Malu S, Zhang M, Ashkin E, Devi S, Williams L, Tieu T, Peng W, Pradeep S, Xu C, Zorro Manrique S, Liu C, Huang L, Chen Y, Forget MA, Haymaker C, Bernatchez C, Satani N, Muller F, Roszik J, Kalra A, Heffernan T, Sood A, Hu J, Amaria R, Davis RE, Hwu P) J Natl Cancer Inst 2018 Jul 01;110(7):777-786 73 Citations |
| 1 | Mutant Cullin 3 causes familial hyperkalemic hypertension via dominant effects. (Ferdaus MZ, Miller LN, Agbor LN, Saritas T, Singer JD, Sigmund CD, McCormick JA) JCI Insight 2017 Dec 21;2(24) 46 Citations |
| 1 | Improvement of Photoreceptor Targeting via Intravitreal Delivery in Mouse and Human Retina Using Combinatory rAAV2 Capsid Mutant Vectors. (Reid CA, Ertel KJ, Lipinski DM) Invest Ophthalmol Vis Sci 2017 Dec 01;58(14):6429-6439 32 Citations |
| 1 | HCN2 channels in the ventral tegmental area regulate behavioral responses to chronic stress. (Zhong P, Vickstrom CR, Liu X, Hu Y, Yu L, Yu HG, Liu QS) Elife 2018 Jan 02;7 63 Citations |
| 1 | Inhibiting Nuclear Phospho-Progesterone Receptor Enhances Antitumor Activity of Onapristone in Uterine Cancer. (Huang Y, Hu W, Huang J, Shen F, Sun Y, Ivan C, Pradeep S, Dood R, Haemmerle M, Jiang D, Mangala LS, Noh K, Hansen JM, Dalton HJ, Previs RA, Nagaraja AS, McGuire M, Jennings NB, Broaddus R, Coleman RL, Sood AK) Mol Cancer Ther 2018 Feb;17(2):464-473 6 Citations |
| 1 | The dynamics of native Atoh7 protein expression during mouse retinal histogenesis, revealed with a new antibody. (Miesfeld JB, Glaser T, Brown NL) Gene Expr Patterns 2018 Jan;27:114-121 22 Citations |
| 1 | Non-chemotherapy drug-induced neutropenia: key points to manage the challenges. (Curtis BR) Hematology Am Soc Hematol Educ Program 2017 Dec 08;2017(1):187-193 67 Citations |
| 1 | Rap1B promotes VEGF-induced endothelial permeability and is required for dynamic regulation of the endothelial barrier. (Lakshmikanthan S, Sobczak M, Li Calzi S, Shaw L, Grant MB, Chrzanowska-Wodnicka M) J Cell Sci 2018 Jan 10;131(1) 46 Citations |
| 2 | The anthelmintic praziquantel is a human serotoninergic G-protein-coupled receptor ligand. (Chan JD, Cupit PM, Gunaratne GS, McCorvy JD, Yang Y, Stoltz K, Webb TR, Dosa PI, Roth BL, Abagyan R, Cunningham C, Marchant JS) Nat Commun 2017 Dec 05;8(1):1910 60 Citations |
| 1 | Developmental Stage-Specific Manifestations of Absent TPO/c-MPL Signalling in Newborn Mice. (Lorenz V, Ramsey H, Liu ZJ, Italiano J Jr, Hoffmeister K, Bihorel S, Mager D, Hu Z, Slayton WB, Kile BT, Sola-Visner M, Ferrer-Marin F) Thromb Haemost 2017 Dec;117(12):2322-2333 16 Citations |
| 1 | Differential Effects of EGFL6 on Tumor versus Wound Angiogenesis. (Noh K, Mangala LS, Han HD, Zhang N, Pradeep S, Wu SY, Ma S, Mora E, Rupaimoole R, Jiang D, Wen Y, Shahzad MMK, Lyons Y, Cho M, Hu W, Nagaraja AS, Haemmerle M, Mak CSL, Chen X, Gharpure KM, Deng H, Xiong W, Kingsley CV, Liu J, Jennings N, Birrer MJ, Bouchard RR, Lopez-Berestein G, Coleman RL, An Z, Sood AK) Cell Rep 2017 Dec 05;21(10):2785-2795 35 Citations |
| 1 | Stromal Lkb1 deficiency leads to gastrointestinal tumorigenesis involving the IL-11-JAK/STAT3 pathway. (Ollila S, Domènech-Moreno E, Laajanen K, Wong IP, Tripathi S, Pentinmikko N, Gao Y, Yan Y, Niemelä EH, Wang TC, Viollet B, Leone G, Katajisto P, Vaahtomeri K, Mäkelä TP) J Clin Invest 2018 Jan 02;128(1):402-414 59 Citations |
| 1 | Role of intestinal Hsp70 in barrier maintenance: contribution of milk to the induction of Hsp70.2. (Rentea RM, Guo Y, Zhu X, Musch MW, Chang EB, Gourlay DM, Liedel JL) Pediatr Surg Int 2018 Mar;34(3):323-330 2 Citations |
| 1 | Resolvins suppress tumor growth and enhance cancer therapy. (Sulciner ML, Serhan CN, Gilligan MM, Mudge DK, Chang J, Gartung A, Lehner KA, Bielenberg DR, Schmidt B, Dalli J, Greene ER, Gus-Brautbar Y, Piwowarski J, Mammoto T, Zurakowski D, Perretti M, Sukhatme VP, Kaipainen A, Kieran MW, Huang S, Panigrahy D) J Exp Med 2018 Jan 02;215(1):115-140 215 Citations |
| 2 | Pancreatic Adenocarcinoma Therapeutic Targets Revealed by Tumor-Stroma Cross-Talk Analyses in Patient-Derived Xenografts. (Nicolle R, Blum Y, Marisa L, Loncle C, Gayet O, Moutardier V, Turrini O, Giovannini M, Bian B, Bigonnet M, Rubis M, Elarouci N, Armenoult L, Ayadi M, Duconseil P, Gasmi M, Ouaissi M, Maignan A, Lomberk G, Boher JM, Ewald J, Bories E, Garnier J, Goncalves A, Poizat F, Raoul JL, Secq V, Garcia S, Grandval P, Barraud-Blanc M, Norguet E, Gilabert M, Delpero JR, Roques J, Calvo E, Guillaumond F, Vasseur S, Urrutia R, de Reyniès A, Dusetti N, Iovanna J) Cell Rep 2017 Nov 28;21(9):2458-2470 153 Citations |
| 1 | Multi-scale, multi-modal analysis uncovers complex relationship at the brain tissue-implant neural interface: new emphasis on the biological interface. (Michelson NJ, Vazquez AL, Eles JR, Salatino JW, Purcell EK, Williams JJ, Cui XT, Kozai TDY) J Neural Eng 2018 Jun;15(3):033001 106 Citations |
| 1 | Peroxisomes contribute to oxidative stress in neurons during doxorubicin-based chemotherapy. (Moruno-Manchon JF, Uzor NE, Kesler SR, Wefel JS, Townley DM, Nagaraja AS, Pradeep S, Mangala LS, Sood AK, Tsvetkov AS) Mol Cell Neurosci 2018 Jan;86:65-71 38 Citations |
| 2 | Species differences and mechanism of action of A3 adenosine receptor allosteric modulators. (Du L, Gao ZG, Paoletta S, Wan TC, Gizewski ET, Barbour S, van Veldhoven JPD, IJzerman AP, Jacobson KA, Auchampach JA) Purinergic Signal 2018 Mar;14(1):59-71 18 Citations |
| 1 | Self-oligomerization regulates stability of survival motor neuron protein isoforms by sequestering an SCFSlmb degron. (Gray KM, Kaifer KA, Baillat D, Wen Y, Bonacci TR, Ebert AD, Raimer AC, Spring AM, Have ST, Glascock JJ, Gupta K, Van Duyne GD, Emanuele MJ, Lamond AI, Wagner EJ, Lorson CL, Matera AG) Mol Biol Cell 2018 Jan 15;29(2):96-110 22 Citations |
| 1 | Chronic lung injury and impaired pulmonary function in a mouse model of acid ceramidase deficiency. (Yu FPS, Islam D, Sikora J, Dworski S, Gurka J, López-Vásquez L, Liu M, Kuebler WM, Levade T, Zhang H, Medin JA) Am J Physiol Lung Cell Mol Physiol 2018 Mar 01;314(3):L406-L420 29 Citations |
| 1 | Optogenetic silencing of nociceptive primary afferents reduces evoked and ongoing bladder pain. (Samineni VK, Mickle AD, Yoon J, Grajales-Reyes JG, Pullen MY, Crawford KE, Noh KN, Gereau GB, Vogt SK, Lai HH, Rogers JA, Gereau RW 4th) Sci Rep 2017 Nov 20;7(1):15865 44 Citations |
| 1 | Stress-Activated NRF2-MDM2 Cascade Controls Neoplastic Progression in Pancreas. (Todoric J, Antonucci L, Di Caro G, Li N, Wu X, Lytle NK, Dhar D, Banerjee S, Fagman JB, Browne CD, Umemura A, Valasek MA, Kessler H, Tarin D, Goggins M, Reya T, Diaz-Meco M, Moscat J, Karin M) Cancer Cell 2017 Dec 11;32(6):824-839.e8 108 Citations |
| 1 | Resveratrol modulates cocaine-induced inhibitory synaptic plasticity in VTA dopamine neurons by inhibiting phosphodiesterases (PDEs). (Li Y, Yu L, Zhao L, Zeng F, Liu QS) Sci Rep 2017 Nov 15;7(1):15657 17 Citations |
| 4 | PLCγ-dependent mTOR signalling controls IL-7-mediated early B cell development. (Yu M, Chen Y, Zeng H, Zheng Y, Fu G, Zhu W, Broeckel U, Aggarwal P, Turner A, Neale G, Guy C, Zhu N, Chi H, Wen R, Wang D) Nat Commun 2017 Nov 13;8(1):1457 31 Citations |
| 1 | In vitro osteogenesis by intracellular uptake of strontium containing bioactive glass nanoparticles. (Naruphontjirakul P, Porter AE, Jones JR) Acta Biomater 2018 Jan 15;66:67-80 112 Citations |
| 1 | Autophagy promotes escape from phosphatidylinositol 3-kinase inhibition in estrogen receptor-positive breast cancer. (Yang W, Hosford SR, Traphagen NA, Shee K, Demidenko E, Liu S, Miller TW) FASEB J 2018 Mar;32(3):1222-1235 25 Citations |
| 2 | Protein engineering of the chemokine CCL20 prevents psoriasiform dermatitis in an IL-23-dependent murine model. (Getschman AE, Imai Y, Larsen O, Peterson FC, Wu X, Rosenkilde MM, Hwang ST, Volkman BF) Proc Natl Acad Sci U S A 2017 Nov 21;114(47):12460-12465 47 Citations |
| 1 | Rapid Loss of RNA Detection by In Situ Hybridization in Stored Tissue Blocks and Preservation by Cold Storage of Unstained Slides. (Baena-Del Valle JA, Zheng Q, Hicks JL, Fedor H, Trock BJ, Morrissey C, Corey E, Cornish TC, Sfanos KS, De Marzo AM) Am J Clin Pathol 2017 Nov 02;148(5):398-415 53 Citations |
| 1 | Acquisition of the Phosphate Transporter NptA Enhances Staphylococcus aureus Pathogenesis by Improving Phosphate Uptake in Divergent Environments. (Kelliher JL, Radin JN, Grim KP, Párraga Solórzano PK, Degnan PH, Kehl-Fie TE) Infect Immun 2018 Jan;86(1) 22 Citations |
| 1 | Induction of anti-VEGF therapy resistance by upregulated expression of microseminoprotein (MSMP). (Mitamura T, Pradeep S, McGuire M, Wu SY, Ma S, Hatakeyama H, Lyons YA, Hisamatsu T, Noh K, Villar-Prados A, Chen X, Ivan C, Rodriguez-Aguayo C, Hu W, Lopez-Berestein G, Coleman RL, Sood AK) Oncogene 2018 Feb 08;37(6):722-731 34 Citations |
| 2 | Modulators of Enterococcus faecalis Cell Envelope Integrity and Antimicrobial Resistance Influence Stable Colonization of the Mammalian Gastrointestinal Tract. (Banla IL, Kommineni S, Hayward M, Rodrigues M, Palmer KL, Salzman NH, Kristich CJ) Infect Immun 2018 Jan;86(1) 23 Citations |
| 1 | Failure of Isoflurane Cardiac Preconditioning in Obese Type 2 Diabetic Mice Involves Aberrant Regulation of MicroRNA-21, Endothelial Nitric-oxide Synthase, and Mitochondrial Complex I. (Ge ZD, Li Y, Qiao S, Bai X, Warltier DC, Kersten JR, Bosnjak ZJ, Liang M) Anesthesiology 2018 Jan;128(1):117-129 16 Citations |
| 1 | VTA mTOR Signaling Regulates Dopamine Dynamics, Cocaine-Induced Synaptic Alterations, and Reward. (Liu X, Li Y, Yu L, Vickstrom CR, Liu QS) Neuropsychopharmacology 2018 Apr;43(5):1066-1077 26 Citations |
| 1 | Characterization of a mouse model of sickle cell trait: parallels to human trait and a novel finding of cutaneous sensitization. (Zappia KJ, Guo Y, Retherford D, Wandersee NJ, Stucky CL, Hillery CA) Br J Haematol 2017 Nov;179(4):657-666 11 Citations |
| 1 | Cancer stemness in bone marrow micrometastases of human breast cancer. (Kuo MC, Kothari AN, Kuo PC, Mi Z) Surgery 2018 Feb;163(2):330-335 21 Citations |
| 1 | Nanog Expression in Embryonic Stem Cells - An Ideal Model System to Dissect Enhancer Function. (Blinka S, Rao S) Bioessays 2017 Dec;39(12) 19 Citations |
| 1 | MRAP2 regulates ghrelin receptor signaling and hunger sensing. (Srisai D, Yin TC, Lee AA, Rouault AAJ, Pearson NA, Grobe JL, Sebag JA) Nat Commun 2017 Sep 28;8(1):713 56 Citations |
| 1 | Kindlin supports platelet integrin αIIbβ3 activation by interacting with paxillin. (Gao J, Huang M, Lai J, Mao K, Sun P, Cao Z, Hu Y, Zhang Y, Schulte ML, Jin C, Wang J, White GC, Xu Z, Ma YQ) J Cell Sci 2017 Nov 01;130(21):3764-3775 51 Citations |
| 2 | Red/near infrared light stimulates release of an endothelium dependent vasodilator and rescues vascular dysfunction in a diabetes model. (Keszler A, Lindemer B, Weihrauch D, Jones D, Hogg N, Lohr NL) Free Radic Biol Med 2017 Dec;113:157-164 36 Citations |
| 1 | Generation of a pancreatic cancer model using a Pdx1-Flp recombinase knock-in allele. (Wu J, Liu X, Nayak SG, Pitarresi JR, Cuitiño MC, Yu L, Hildreth BE 3rd, Thies KA, Schilling DJ, Fernandez SA, Leone G, Ostrowski MC) PLoS One 2017;12(9):e0184984 17 Citations |
| 2 | The two novel DLL4-targeting antibody-drug conjugates MvM03 and MGD03 show potent anti-tumour activity in breast cancer xenograft models. (Wang S, Zhou R, Sun F, Li R, Wang M, Wu M) Cancer Lett 2017 Nov 28;409:125-136 12 Citations |
| 2 | T Cells Deficient in Diacylglycerol Kinase ζ Are Resistant to PD-1 Inhibition and Help Create Persistent Host Immunity to Leukemia. (Jing W, Gershan JA, Holzhauer S, Weber J, Palen K, McOlash L, Pulakanti K, Wesley E, Rao S, Johnson BD, Riese MJ) Cancer Res 2017 Oct 15;77(20):5676-5686 15 Citations |
| 3 | Twist1 in Hypoxia-induced Pulmonary Hypertension through Transforming Growth Factor-β-Smad Signaling. (Mammoto T, Muyleart M, Konduri GG, Mammoto A) Am J Respir Cell Mol Biol 2018 Feb;58(2):194-207 76 Citations |
| 1 | NF-κB regulates GDF-15 to suppress macrophage surveillance during early tumor development. (Ratnam NM, Peterson JM, Talbert EE, Ladner KJ, Rajasekera PV, Schmidt CR, Dillhoff ME, Swanson BJ, Haverick E, Kladney RD, Williams TM, Leone GW, Wang DJ, Guttridge DC) J Clin Invest 2017 Oct 02;127(10):3796-3809 129 Citations |
| 1 | Mechanotransduction signaling in podocytes from fluid flow shear stress. (Srivastava T, Dai H, Heruth DP, Alon US, Garola RE, Zhou J, Duncan RS, El-Meanawy A, McCarthy ET, Sharma R, Johnson ML, Savin VJ, Sharma M) Am J Physiol Renal Physiol 2018 Jan 01;314(1):F22-F34 30 Citations |
| 1 | Natural immunoglobulin M initiates an inflammatory response important for both hepatic ischemia reperfusion injury and regeneration in mice. (Marshall K, Jin J, Atkinson C, Alawieh A, Qiao F, Lei B, Chavin KD, He S, Tomlinson S) Hepatology 2018 Feb;67(2):721-735 30 Citations |
| 3 | Selective Deletion of Renin-b in the Brain Alters Drinking and Metabolism. (Shinohara K, Nakagawa P, Gomez J, Morgan DA, Littlejohn NK, Folchert MD, Weidemann BJ, Liu X, Walsh SA, Ponto LL, Rahmouni K, Grobe JL, Sigmund CD) Hypertension 2017 Nov;70(5):990-997 18 Citations |
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| 1 | KLF9 and JNK3 Interact to Suppress Axon Regeneration in the Adult CNS. (Apara A, Galvao J, Wang Y, Blackmore M, Trillo A, Iwao K, Brown DP Jr, Fernandes KA, Huang A, Nguyen T, Ashouri M, Zhang X, Shaw PX, Kunzevitzky NJ, Moore DL, Libby RT, Goldberg JL) J Neurosci 2017 Oct 04;37(40):9632-9644 86 Citations |
| 1 | Origin and production of inflammatory perivascular macrophages in pulmonary hypertension. (Florentin J, Dutta P) Cytokine 2017 Dec;100:11-15 35 Citations |
| 1 | Macrophages Facilitate Resistance to Anti-VEGF Therapy by Altered VEGFR Expression. (Dalton HJ, Pradeep S, McGuire M, Hailemichael Y, Ma S, Lyons Y, Armaiz-Pena GN, Previs RA, Hansen JM, Rupaimoole R, Gonzalez-Villasana V, Cho MS, Wu SY, Mangala LS, Jennings NB, Hu W, Langley R, Mu H, Andreeff M, Bar-Eli M, Overwijk W, Ram P, Lopez-Berestein G, Coleman RL, Sood AK) Clin Cancer Res 2017 Nov 15;23(22):7034-7046 77 Citations |
| 1 | Distinct effects of estrogen receptor antagonism on object recognition and spatial memory consolidation in ovariectomized mice. (Kim J, Frick KM) Psychoneuroendocrinology 2017 Nov;85:110-114 33 Citations |
| 2 | Single-Immunoglobulin Interleukin-1-Related Receptor regulates vulnerability to TLR4-mediated necrotizing enterocolitis in a mouse model. (Fawley J, Cuna A, Menden HL, McElroy S, Umar S, Welak SR, Gourlay DM, Li X, Sampath V) Pediatr Res 2018 Jan;83(1-1):164-174 30 Citations |
| 1 | Mechanical induction of dentin-like differentiation by adult mouse bone marrow stromal cells using compressive scaffolds. (Hashmi B, Mammoto T, Weaver J, Ferrante T, Jiang A, Jiang E, Feliz J, Ingber DE) Stem Cell Res 2017 Oct;24:55-60 15 Citations |
| 1 | Tumor Mutational Burden as an Independent Predictor of Response to Immunotherapy in Diverse Cancers. (Goodman AM, Kato S, Bazhenova L, Patel SP, Frampton GM, Miller V, Stephens PJ, Daniels GA, Kurzrock R) Mol Cancer Ther 2017 Nov;16(11):2598-2608 1739 Citations |
| 1 | Alloimmune Responses of Humanized Mice to Human Pluripotent Stem Cell Therapeutics. (Kooreman NG, de Almeida PE, Stack JP, Nelakanti RV, Diecke S, Shao NY, Swijnenburg RJ, Sanchez-Freire V, Matsa E, Liu C, Connolly AJ, Hamming JF, Quax PHA, Brehm MA, Greiner DL, Shultz LD, Wu JC) Cell Rep 2017 Aug 22;20(8):1978-1990 31 Citations |
| 1 | Neurobiological correlates of state-dependent context fear. (Meyer MAA, Corcoran KA, Chen HJ, Gallego S, Li G, Tiruveedhula VV, Cook JM, Radulovic J) Learn Mem 2017 Sep;24(9):385-391 13 Citations |
| 1 | RUNX1 is required for oncogenic Myb and Myc enhancer activity in T-cell acute lymphoblastic leukemia. (Choi A, Illendula A, Pulikkan JA, Roderick JE, Tesell J, Yu J, Hermance N, Zhu LJ, Castilla LH, Bushweller JH, Kelliher MA) Blood 2017 Oct 12;130(15):1722-1733 66 Citations |
| 1 | Neural stem cell mediated recovery is enhanced by Chondroitinase ABC pretreatment in chronic cervical spinal cord injury. (Suzuki H, Ahuja CS, Salewski RP, Li L, Satkunendrarajah K, Nagoshi N, Shibata S, Fehlings MG) PLoS One 2017;12(8):e0182339 82 Citations |
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| 1 | Accumbens Mechanisms for Cued Sucrose Seeking. (Bobadilla AC, Garcia-Keller C, Heinsbroek JA, Scofield MD, Chareunsouk V, Monforton C, Kalivas PW) Neuropsychopharmacology 2017 Nov;42(12):2377-2386 20 Citations |
| 1 | DNA binding drives the association of BRG1/hBRM bromodomains with nucleosomes. (Morrison EA, Sanchez JC, Ronan JL, Farrell DP, Varzavand K, Johnson JK, Gu BX, Crabtree GR, Musselman CA) Nat Commun 2017 Jul 14;8:16080 57 Citations |
| 1 | B Cell-Specific Expression of Ataxia-Telangiectasia Mutated Protein Kinase Promotes Chronic Gammaherpesvirus Infection. (Darrah EJ, Kulinski JM, Mboko WP, Xin G, Malherbe LP, Gauld SB, Cui W, Tarakanova VL) J Virol 2017 Oct 01;91(19) 9 Citations |
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| 1 | Small molecule metalloprotease inhibitor with in vitro, ex vivo and in vivo efficacy against botulinum neurotoxin serotype A. (Jacobson AR, Adler M, Silvaggi NR, Allen KN, Smith GM, Fredenburg RA, Stein RL, Park JB, Feng X, Shoemaker CB, Deshpande SS, Goodnough MC, Malizio CJ, Johnson EA, Pellett S, Tepp WH, Tzipori S) Toxicon 2017 Oct;137:36-47 12 Citations |
| 1 | Thermoneutrality but Not UCP1 Deficiency Suppresses Monocyte Mobilization Into Blood. (Williams JW, Elvington A, Ivanov S, Kessler S, Luehmann H, Baba O, Saunders BT, Kim KW, Johnson MW, Craft CS, Choi JH, Sorci-Thomas MG, Zinselmeyer BH, Brestoff JR, Liu Y, Randolph GJ) Circ Res 2017 Sep 01;121(6):662-676 39 Citations |
| 1 | Development of insulin resistance through sprouting of inflammatory markers during hypoxia in 3T3-L1 adipocytes and amelioration with curcumin. (Priyanka A, Shyni GL, Anupama N, Raj PS, Anusree SS, Raghu KG) Eur J Pharmacol 2017 Oct 05;812:73-81 20 Citations |
| 1 | Genetic Interference With Endothelial PPAR-γ (Peroxisome Proliferator-Activated Receptor-γ) Augments Effects of Angiotensin II While Impairing Responses to Angiotensin 1-7. (De Silva TM, Hu C, Kinzenbaw DA, Modrick ML, Sigmund CD, Faraci FM) Hypertension 2017 Sep;70(3):559-565 16 Citations |
| 1 | Attenuation of RNA polymerase II pausing mitigates BRCA1-associated R-loop accumulation and tumorigenesis. (Zhang X, Chiang HC, Wang Y, Zhang C, Smith S, Zhao X, Nair SJ, Michalek J, Jatoi I, Lautner M, Oliver B, Wang H, Petit A, Soler T, Brunet J, Mateo F, Angel Pujana M, Poggi E, Chaldekas K, Isaacs C, Peshkin BN, Ochoa O, Chedin F, Theoharis C, Sun LZ, Curiel TJ, Elledge R, Jin VX, Hu Y, Li R) Nat Commun 2017 Jun 26;8:15908 125 Citations |
| 2 | Astrocyte-produced miR-146a as a mediator of motor neuron loss in spinal muscular atrophy. (Sison SL, Patitucci TN, Seminary ER, Villalon E, Lorson CL, Ebert AD) Hum Mol Genet 2017 Sep 01;26(17):3409-3420 63 Citations |
| 1 | Long days enhance recognition memory and increase insulin-like growth factor 2 in the hippocampus. (Dellapolla A, Kloehn I, Pancholi H, Callif B, Wertz D, Rohr KE, Hurley MM, Baker KM, Hattar S, Gilmartin MR, Evans JA) Sci Rep 2017 Jun 20;7(1):3925 13 Citations |
| 2 | Cardiotonic Steroids Stimulate Macrophage Inflammatory Responses Through a Pathway Involving CD36, TLR4, and Na/K-ATPase. (Chen Y, Huang W, Yang M, Xin G, Cui W, Xie Z, Silverstein RL) Arterioscler Thromb Vasc Biol 2017 Aug;37(8):1462-1469 27 Citations |
| 2 | Ultrasound-sensitive nanoparticle aggregates for targeted drug delivery. (Papa AL, Korin N, Kanapathipillai M, Mammoto A, Mammoto T, Jiang A, Mannix R, Uzun O, Johnson C, Bhatta D, Cuneo G, Ingber DE) Biomaterials 2017 Sep;139:187-194 69 Citations |
| 1 | miRNA-mediated post-transcriptional silencing of transgenes leads to increased adeno-associated viral vector yield and targeting specificity. (Reid CA, Boye SL, Hauswirth WW, Lipinski DM) Gene Ther 2017 Aug;24(8):462-469 12 Citations |
| 1 | Role of Platelet-Derived Tgfβ1 in the Progression of Ovarian Cancer. (Hu Q, Hisamatsu T, Haemmerle M, Cho MS, Pradeep S, Rupaimoole R, Rodriguez-Aguayo C, Lopez-Berestein G, Wong STC, Sood AK, Afshar-Kharghan V) Clin Cancer Res 2017 Sep 15;23(18):5611-5621 61 Citations |
| 1 | Shear stress induces endothelial-to-mesenchymal transition via the transcription factor Snail. (Mahmoud MM, Serbanovic-Canic J, Feng S, Souilhol C, Xing R, Hsiao S, Mammoto A, Chen J, Ariaans M, Francis SE, Van der Heiden K, Ridger V, Evans PC) Sci Rep 2017 Jun 13;7(1):3375 147 Citations |
| 1 | Elotuzumab as a novel anti-myeloma immunotherapy. (Radhakrishnan SV, Bhardwaj N, Steinbach M, Weidner J, Luetkens T, Atanackovic D) Hum Vaccin Immunother 2017 Aug 03;13(8):1751-1757 5 Citations |
| 1 | Transgenic overexpression of GTP cyclohydrolase 1 in cardiomyocytes ameliorates post-infarction cardiac remodeling. (Liu Y, Baumgardt SL, Fang J, Shi Y, Qiao S, Bosnjak ZJ, Vásquez-Vivar J, Xia Z, Warltier DC, Kersten JR, Ge ZD) Sci Rep 2017 Jun 08;7(1):3093 14 Citations |
| 1 | Exosome-Derived miR-25-3p and miR-92a-3p Stimulate Liposarcoma Progression. (Casadei L, Calore F, Creighton CJ, Guescini M, Batte K, Iwenofu OH, Zewdu A, Braggio DA, Bill KL, Fadda P, Lovat F, Lopez G, Gasparini P, Chen JL, Kladney RD, Leone G, Lev D, Croce CM, Pollock RE) Cancer Res 2017 Jul 15;77(14):3846-3856 156 Citations |
| 1 | Return of the lysergamides. Part IV: Analytical and pharmacological characterization of lysergic acid morpholide (LSM-775). (Brandt SD, Kavanagh PV, Twamley B, Westphal F, Elliott SP, Wallach J, Stratford A, Klein LM, McCorvy JD, Nichols DE, Halberstadt AL) Drug Test Anal 2018 Feb;10(2):310-322 47 Citations |
| 1 | Uncontrolled Hemorrhagic Shock Modeled via Liver Laceration in Mice with Real Time Hemodynamic Monitoring. (Dyer M, Haldeman S, Gutierrez A, Kohut L, Sen Gupta A, Neal MD) J Vis Exp 2017 May 21(123) 14 Citations |
| 1 | HMGB1-RAGE pathway drives peroxynitrite signaling-induced IBD-like inflammation in murine nonalcoholic fatty liver disease. (Chandrashekaran V, Seth RK, Dattaroy D, Alhasson F, Ziolenka J, Carson J, Berger FG, Kalyanaraman B, Diehl AM, Chatterjee S) Redox Biol 2017 Oct;13:8-19 57 Citations |
| 1 | T cells lacking HDAC11 have increased effector functions and mediate enhanced alloreactivity in a murine model. (Woods DM, Woan KV, Cheng F, Sodré AL, Wang D, Wu Y, Wang Z, Chen J, Powers J, Pinilla-Ibarz J, Yu Y, Zhang Y, Wu X, Zheng X, Weber J, Hancock WW, Seto E, Villagra A, Yu XZ, Sotomayor EM) Blood 2017 Jul 13;130(2):146-155 60 Citations |
| 1 | HAND2 Target Gene Regulatory Networks Control Atrioventricular Canal and Cardiac Valve Development. (Laurent F, Girdziusaite A, Gamart J, Barozzi I, Osterwalder M, Akiyama JA, Lincoln J, Lopez-Rios J, Visel A, Zuniga A, Zeller R) Cell Rep 2017 May 23;19(8):1602-1613 48 Citations |
| 1 | Discovery of Stromal Regulatory Networks that Suppress Ras-Sensitized Epithelial Cell Proliferation. (Liu H, Dowdle JA, Khurshid S, Sullivan NJ, Bertos N, Rambani K, Mair M, Daniel P, Wheeler E, Tang X, Toth K, Lause M, Harrigan ME, Eiring K, Sullivan C, Sullivan MJ, Chang SW, Srivastava S, Conway JS, Kladney R, McElroy J, Bae S, Lu Y, Tofigh A, Saleh SMI, Fernandez SA, Parvin JD, Coppola V, Macrae ER, Majumder S, Shapiro CL, Yee LD, Ramaswamy B, Hallett M, Ostrowski MC, Park M, Chamberlin HM, Leone G) Dev Cell 2017 May 22;41(4):392-407.e6 25 Citations |
| 1 | Long-term surveillance of zinc implant in murine artery: Surprisingly steady biocorrosion rate. (Drelich AJ, Zhao S, Guillory RJ 2nd, Drelich JW, Goldman J) Acta Biomater 2017 Aug;58:539-549 155 Citations |
| 1 | Rap1b Is an Effector of Axin2 Regulating Crosstalk of Signaling Pathways During Skeletal Development. (Maruyama T, Jiang M, Abbott A, Yu HI, Huang Q, Chrzanowska-Wodnicka M, Chen EI, Hsu W) J Bone Miner Res 2017 Sep;32(9):1816-1828 28 Citations |
| 1 | Myeloperoxidase: A new player in autoimmunity. (Strzepa A, Pritchard KA, Dittel BN) Cell Immunol 2017 Jul;317:1-8 191 Citations |
| 1 | Hypertension-Causing Mutation in Peroxisome Proliferator-Activated Receptor γ Impairs Nuclear Export of Nuclear Factor-κB p65 in Vascular Smooth Muscle. (Mukohda M, Lu KT, Guo DF, Wu J, Keen HL, Liu X, Ketsawatsomkron P, Stump M, Rahmouni K, Quelle FW, Sigmund CD) Hypertension 2017 Jul;70(1):174-182 24 Citations |
| 1 | Stromal PDGFR-α Activation Enhances Matrix Stiffness, Impedes Mammary Ductal Development, and Accelerates Tumor Growth. (Hammer AM, Sizemore GM, Shukla VC, Avendano A, Sizemore ST, Chang JJ, Kladney RD, Cuitiño MC, Thies KA, Verfurth Q, Chakravarti A, Yee LD, Leone G, Song JW, Ghadiali SN, Ostrowski MC) Neoplasia 2017 Jun;19(6):496-508 49 Citations |
| 1 | Comprehensive Assessments of Energy Balance in Mice. (Grobe JL) Methods Mol Biol 2017;1614:123-146 37 Citations |
| 1 | Vandetanib and cabozantinib potentiate mitochondria-targeted agents to suppress medullary thyroid carcinoma cells. (Starenki D, Hong SK, Wu PK, Park JI) Cancer Biol Ther 2017 Jul 03;18(7):473-483 18 Citations |
| 1 | Altered striatal endocannabinoid signaling in a transgenic mouse model of spinocerebellar ataxia type-3. (Rodríguez-Cueto C, Hernández-Gálvez M, Hillard CJ, Maciel P, Valdeolivas S, Ramos JA, Gómez-Ruiz M, Fernández-Ruiz J) PLoS One 2017;12(4):e0176521 6 Citations |
| 4 | Acid ceramidase is a novel drug target for pediatric brain tumors. (Doan NB, Nguyen HS, Montoure A, Al-Gizawiy MM, Mueller WM, Kurpad S, Rand SD, Connelly JM, Chitambar CR, Schmainda KM, Mirza SP) Oncotarget 2017 Apr 11;8(15):24753-24761 28 Citations |
| 3 | Combined AURKA and H3K9 Methyltransferase Targeting Inhibits Cell Growth By Inducing Mitotic Catastrophe. (Mathison A, Salmonson A, Missfeldt M, Bintz J, Williams M, Kossak S, Nair A, de Assuncao TM, Christensen T, Buttar N, Iovanna J, Huebert R, Lomberk G) Mol Cancer Res 2017 Aug;15(8):984-997 16 Citations |
| 2 | Alleviation of Multiple Asthmatic Pathologic Features with Orally Available and Subtype Selective GABAA Receptor Modulators. (Forkuo GS, Nieman AN, Yuan NY, Kodali R, Yu OB, Zahn NM, Jahan R, Li G, Stephen MR, Guthrie ML, Poe MM, Hartzler BD, Harris TW, Yocum GT, Emala CW, Steeber DA, Stafford DC, Cook JM, Arnold LA) Mol Pharm 2017 Jun 05;14(6):2088-2098 29 Citations |
| 1 | Targeting the centriolar replication factor STIL synergizes with DNA damaging agents for treatment of ovarian cancer. (Rabinowicz N, Mangala LS, Brown KR, Checa-Rodriguez C, Castiel A, Moskovich O, Zarfati G, Trakhtenbrot L, Levy-Barda A, Jiang D, Rodriguez-Aguayo C, Pradeep S, van Praag Y, Lopez-Berestein G, David A, Novikov I, Huertas P, Rottapel R, Sood AK, Izraeli S) Oncotarget 2017 Apr 18;8(16):27380-27392 9 Citations |
| 1 | Therapeutic sensitivity to Rac GTPase inhibition requires consequential suppression of mTORC1, AKT, and MEK signaling in breast cancer. (Hampsch RA, Shee K, Bates D, Lewis LD, Désiré L, Leblond B, Demidenko E, Stefan K, Huang YH, Miller TW) Oncotarget 2017 Mar 28;8(13):21806-21817 32 Citations |
| 1 | Targeting the PIM protein kinases for the treatment of a T-cell acute lymphoblastic leukemia subset. (Padi SKR, Luevano LA, An N, Pandey R, Singh N, Song JH, Aster JC, Yu XZ, Mehrotra S, Kraft AS) Oncotarget 2017 May 02;8(18):30199-30216 36 Citations |
| 1 | The Inhibitory G Protein α-Subunit, Gαz, Promotes Type 1 Diabetes-Like Pathophysiology in NOD Mice. (Fenske RJ, Cadena MT, Harenda QE, Wienkes HN, Carbajal K, Schaid MD, Laundre E, Brill AL, Truchan NA, Brar H, Wisinski J, Cai J, Graham TE, Engin F, Kimple ME) Endocrinology 2017 Jun 01;158(6):1645-1658 18 Citations |
| 1 | Cysteinyl leukotriene receptor 1 facilitates tumorigenesis in a mouse model of colitis-associated colon cancer. (Osman J, Savari S, Chandrashekar NK, Bellamkonda K, Douglas D, Sjölander A) Oncotarget 2017 May 23;8(21):34773-34786 26 Citations |
| 1 | Identification of RUNX1 as a Mediator of Aberrant Retinal Angiogenesis. (Lam JD, Oh DJ, Wong LL, Amarnani D, Park-Windhol C, Sanchez AV, Cardona-Velez J, McGuone D, Stemmer-Rachamimov AO, Eliott D, Bielenberg DR, van Zyl T, Shen L, Gai X, D'Amore PA, Kim LA, Arboleda-Velasquez JF) Diabetes 2017 Jul;66(7):1950-1956 67 Citations |
| 3 | Mito-Apocynin Prevents Mitochondrial Dysfunction, Microglial Activation, Oxidative Damage, and Progressive Neurodegeneration in MitoPark Transgenic Mice. (Langley M, Ghosh A, Charli A, Sarkar S, Ay M, Luo J, Zielonka J, Brenza T, Bennett B, Jin H, Ghaisas S, Schlichtmann B, Kim D, Anantharam V, Kanthasamy A, Narasimhan B, Kalyanaraman B, Kanthasamy AG) Antioxid Redox Signal 2017 Nov 10;27(14):1048-1066 106 Citations |
| 1 | CD137 Plays Both Pathogenic and Protective Roles in Type 1 Diabetes Development in NOD Mice. (Forsberg MH, Ciecko AE, Bednar KJ, Itoh A, Kachapati K, Ridgway WM, Chen YG) J Immunol 2017 May 15;198(10):3857-3868 19 Citations |
| 2 | Mitochondrial Cx43 hemichannels contribute to mitochondrial calcium entry and cell death in the heart. (Gadicherla AK, Wang N, Bulic M, Agullo-Pascual E, Lissoni A, De Smet M, Delmar M, Bultynck G, Krysko DV, Camara A, Schlüter KD, Schulz R, Kwok WM, Leybaert L) Basic Res Cardiol 2017 May;112(3):27 109 Citations |
| 1 | Detailed Characterization of the In Vitro Pharmacological and Pharmacokinetic Properties of N-(2-Hydroxybenzyl)-2,5-Dimethoxy-4-Cyanophenylethylamine (25CN-NBOH), a Highly Selective and Brain-Penetrant 5-HT2A Receptor Agonist. (Jensen AA, McCorvy JD, Leth-Petersen S, Bundgaard C, Liebscher G, Kenakin TP, Bräuner-Osborne H, Kehler J, Kristensen JL) J Pharmacol Exp Ther 2017 Jun;361(3):441-453 49 Citations |
| 1 | Vasodilation of Isolated Vessels and the Isolation of the Extracellular Matrix of Tight-skin Mice. (Weihrauch D, Krolikowski JG, Jones DW, Zaman T, Bamkole O, Struve J, Pagel PS, Lohr NL, Pritchard KA Jr) J Vis Exp 2017 Mar 24(121) 2 Citations |
| 1 | Retinol-binding protein 7 is an endothelium-specific PPARγ cofactor mediating an antioxidant response through adiponectin. (Hu C, Keen HL, Lu KT, Liu X, Wu J, Davis DR, Ibeawuchi SC, Vogel S, Quelle FW, Sigmund CD) JCI Insight 2017 Mar 23;2(6):e91738 29 Citations |
| 1 | In vitro and in vivo fitness costs associated with Mycobacterium tuberculosis RpoB mutation H526D. (Rifat D, Campodónico VL, Tao J, Miller JA, Alp A, Yao Y, Karakousis PC) Future Microbiol 2017 Jul;12(9):753-765 22 Citations |
| 2 | Identity and function of a cardiac mitochondrial small conductance Ca2+-activated K+ channel splice variant. (Yang M, Camara AKS, Aldakkak M, Kwok WM, Stowe DF) Biochim Biophys Acta Bioenerg 2017 Jun;1858(6):442-458 28 Citations |
| 1 | Acid Ceramidase Deficiency in Mice Results in a Broad Range of Central Nervous System Abnormalities. (Sikora J, Dworski S, Jones EE, Kamani MA, Micsenyi MC, Sawada T, Le Faouder P, Bertrand-Michel J, Dupuy A, Dunn CK, Xuan ICY, Casas J, Fabrias G, Hampson DR, Levade T, Drake RR, Medin JA, Walkley SU) Am J Pathol 2017 Apr;187(4):864-883 45 Citations |
| 3 | Platelet CD36 promotes thrombosis by activating redox sensor ERK5 in hyperlipidemic conditions. (Yang M, Cooley BC, Li W, Chen Y, Vasquez-Vivar J, Scoggins NO, Cameron SJ, Morrell CN, Silverstein RL) Blood 2017 May 25;129(21):2917-2927 79 Citations |
| 1 | Identification of a novel, fast-acting GABAergic antidepressant. (McMurray KMJ, Ramaker MJ, Barkley-Levenson AM, Sidhu PS, Elkin PK, Reddy MK, Guthrie ML, Cook JM, Rawal VH, Arnold LA, Dulawa SC, Palmer AA) Mol Psychiatry 2018 Feb;23(2):384-391 34 Citations |
| 1 | Scaffold Repurposing of Nucleosides (Adenosine Receptor Agonists): Enhanced Activity at the Human Dopamine and Norepinephrine Sodium Symporters. (Tosh DK, Janowsky A, Eshleman AJ, Warnick E, Gao ZG, Chen Z, Gizewski E, Auchampach JA, Salvemini D, Jacobson KA) J Med Chem 2017 Apr 13;60(7):3109-3123 16 Citations |
| 1 | Pseudomonas aeruginosa infection liberates transmissible, cytotoxic prion amyloids. (Balczon R, Morrow KA, Zhou C, Edmonds B, Alexeyev M, Pittet JF, Wagener BM, Moser SA, Leavesley S, Zha X, Frank DW, Stevens T) FASEB J 2017 Jul;31(7):2785-2796 33 Citations |
| 1 | Deciphering the interplay between cysteine synthase and thiol cascade proteins in modulating Amphotericin B resistance and survival of Leishmania donovani under oxidative stress. (Singh K, Ali V, Pratap Singh K, Gupta P, Suman SS, Ghosh AK, Bimal S, Pandey K, Das P) Redox Biol 2017 Aug;12:350-366 42 Citations |
| 1 | Biodegradable inorganic-organic hybrids of methacrylate star polymers for bone regeneration. (Chung JJ, Fujita Y, Li S, Stevens MM, Kasuga T, Georgiou TK, Jones JR) Acta Biomater 2017 May;54:411-418 30 Citations |
| 1 | Small-Molecule Stabilization of 14-3-3 Protein-Protein Interactions Stimulates Axon Regeneration. (Kaplan A, Morquette B, Kroner A, Leong S, Madwar C, Sanz R, Banerjee SL, Antel J, Bisson N, David S, Fournier AE) Neuron 2017 Mar 08;93(5):1082-1093.e5 70 Citations |
| 2 | Gene expression profiling of patient-derived pancreatic cancer xenografts predicts sensitivity to the BET bromodomain inhibitor JQ1: implications for individualized medicine efforts. (Bian B, Bigonnet M, Gayet O, Loncle C, Maignan A, Gilabert M, Moutardier V, Garcia S, Turrini O, Delpero JR, Giovannini M, Grandval P, Gasmi M, Ouaissi M, Secq V, Poizat F, Nicolle R, Blum Y, Marisa L, Rubis M, Raoul JL, Bradner JE, Qi J, Lomberk G, Urrutia R, Saul A, Dusetti N, Iovanna J) EMBO Mol Med 2017 Apr;9(4):482-497 60 Citations |
| 1 | Skeletal muscle PGC-1β signaling is sufficient to drive an endurance exercise phenotype and to counteract components of detraining in mice. (Lee S, Leone TC, Rogosa L, Rumsey J, Ayala J, Coen PM, Fitts RH, Vega RB, Kelly DP) Am J Physiol Endocrinol Metab 2017 May 01;312(5):E394-E406 15 Citations |
| 2 | Pharmacological and antihyperalgesic properties of the novel α2/3 preferring GABAA receptor ligand MP-III-024. (Fischer BD, Schlitt RJ, Hamade BZ, Rehman S, Ernst M, Poe MM, Li G, Kodali R, Arnold LA, Cook JM) Brain Res Bull 2017 May;131:62-69 25 Citations |
| 1 | Human Mesenchymal Stem Cell-Educated Macrophages Are a Distinct High IL-6-Producing Subset that Confer Protection in Graft-versus-Host-Disease and Radiation Injury Models. (Bouchlaka MN, Moffitt AB, Kim J, Kink JA, Bloom DD, Love C, Dave S, Hematti P, Capitini CM) Biol Blood Marrow Transplant 2017 Jun;23(6):897-905 54 Citations |
| 1 | TRIP13-deficient tubular epithelial cells are susceptible to apoptosis following acute kidney injury. (Pressly JD, Hama T, Brien SO, Regner KR, Park F) Sci Rep 2017 Mar 03;7:43196 16 Citations |
| 1 | TRPV4 ion channel is a novel regulator of dermal myofibroblast differentiation. (Sharma S, Goswami R, Merth M, Cohen J, Lei KY, Zhang DX, Rahaman SO) Am J Physiol Cell Physiol 2017 May 01;312(5):C562-C572 60 Citations |
| 1 | LIGHT Elevation Enhances Immune Eradication of Colon Cancer Metastases. (Qiao G, Qin J, Kunda N, Calata JF, Mahmud DL, Gann P, Fu YX, Rosenberg SA, Prabhakar BS, Maker AV) Cancer Res 2017 Apr 15;77(8):1880-1891 34 Citations |
| 1 | Nutrient-driven O-linked N-acetylglucosamine (O-GlcNAc) cycling impacts neurodevelopmental timing and metabolism. (Olivier-Van Stichelen S, Wang P, Comly M, Love DC, Hanover JA) J Biol Chem 2017 Apr 14;292(15):6076-6085 61 Citations |
| 1 | Hepatic deficiency of the pioneer transcription factor FoxA restricts hepatitis B virus biosynthesis by the developmental regulation of viral DNA methylation. (McFadden VC, Shalaby RE, Iram S, Oropeza CE, Landolfi JA, Lyubimov AV, Maienschein-Cline M, Green SJ, Kaestner KH, McLachlan A) PLoS Pathog 2017 Feb;13(2):e1006239 20 Citations |
| 2 | The Epac-Phospholipase Cε Pathway Regulates Endocannabinoid Signaling and Cocaine-Induced Disinhibition of Ventral Tegmental Area Dopamine Neurons. (Tong J, Liu X, Vickstrom C, Li Y, Yu L, Lu Y, Smrcka AV, Liu QS) J Neurosci 2017 Mar 15;37(11):3030-3044 23 Citations |
| 1 | Genetic inhibition of neurotransmission reveals role of glutamatergic input to dopamine neurons in high-effort behavior. (Hutchison MA, Gu X, Adrover MF, Lee MR, Hnasko TS, Alvarez VA, Lu W) Mol Psychiatry 2018 May;23(5):1213-1225 12 Citations |
| 4 | Diet-induced obesity links to ER positive breast cancer progression via LPA/PKD-1-CD36 signaling-mediated microvascular remodeling. (Dong L, Yuan Y, Opansky C, Chen Y, Aguilera-Barrantes I, Wu S, Yuan R, Cao Q, Cheng YC, Sahoo D, Silverstein RL, Ren B) Oncotarget 2017 Apr 04;8(14):22550-22562 29 Citations |
| 1 | Augmentation of Muscle Blood Flow by Ultrasound Cavitation Is Mediated by ATP and Purinergic Signaling. (Belcik JT, Davidson BP, Xie A, Wu MD, Yadava M, Qi Y, Liang S, Chon CR, Ammi AY, Field J, Harmann L, Chilian WM, Linden J, Lindner JR) Circulation 2017 Mar 28;135(13):1240-1252 107 Citations |
| 1 | annoPeak: a web application to annotate and visualize peaks from ChIP-seq/ChIP-exo-seq. (Tang X, Srivastava A, Liu H, Machiraju R, Huang K, Leone G) Bioinformatics 2017 May 15;33(10):1570-1571 5 Citations |
| 1 | DEK-targeting DNA aptamers as therapeutics for inflammatory arthritis. (Mor-Vaknin N, Saha A, Legendre M, Carmona-Rivera C, Amin MA, Rabquer BJ, Gonzales-Hernandez MJ, Jorns J, Mohan S, Yalavarthi S, Pai DA, Angevine K, Almburg SJ, Knight JS, Adams BS, Koch AE, Fox DA, Engelke DR, Kaplan MJ, Markovitz DM) Nat Commun 2017 Feb 06;8:14252 84 Citations |
| 3 | NMR Structure of the C-Terminal Transmembrane Domain of the HDL Receptor, SR-BI, and a Functionally Relevant Leucine Zipper Motif. (Chadwick AC, Jensen DR, Hanson PJ, Lange PT, Proudfoot SC, Peterson FC, Volkman BF, Sahoo D) Structure 2017 Mar 07;25(3):446-457 20 Citations |
| 1 | Tumor-Penetrating Nanoparticles for Enhanced Anticancer Activity of Combined Photodynamic and Hypoxia-Activated Therapy. (Wang Y, Xie Y, Li J, Peng ZH, Sheinin Y, Zhou J, Oupický D) ACS Nano 2017 Feb 28;11(2):2227-2238 434 Citations |
| 1 | Colon cancer cell treatment with rose bengal generates a protective immune response via immunogenic cell death. (Qin J, Kunda N, Qiao G, Calata JF, Pardiwala K, Prabhakar BS, Maker AV) Cell Death Dis 2017 Feb 02;8(2):e2584 67 Citations |
| 1 | Antinociceptive Effects of a Novel α2/α3-Subtype Selective GABAA Receptor Positive Allosteric Modulator. (Lewter LA, Fisher JL, Siemian JN, Methuku KR, Poe MM, Cook JM, Li JX) ACS Chem Neurosci 2017 Jun 21;8(6):1305-1312 37 Citations |
| 1 | Dosage-dependent copy number gains in E2f1 and E2f3 drive hepatocellular carcinoma. (Kent LN, Bae S, Tsai SY, Tang X, Srivastava A, Koivisto C, Martin CK, Ridolfi E, Miller GC, Zorko SM, Plevris E, Hadjiyannis Y, Perez M, Nolan E, Kladney R, Westendorp B, de Bruin A, Fernandez S, Rosol TJ, Pohar KS, Pipas JM, Leone G) J Clin Invest 2017 Mar 01;127(3):830-842 89 Citations |
| 1 | Flexible Near-Field Wireless Optoelectronics as Subdermal Implants for Broad Applications in Optogenetics. (Shin G, Gomez AM, Al-Hasani R, Jeong YR, Kim J, Xie Z, Banks A, Lee SM, Han SY, Yoo CJ, Lee JL, Lee SH, Kurniawan J, Tureb J, Guo Z, Yoon J, Park SI, Bang SY, Nam Y, Walicki MC, Samineni VK, Mickle AD, Lee K, Heo SY, McCall JG, Pan T, Wang L, Feng X, Kim TI, Kim JK, Li Y, Huang Y, Gereau RW 4th, Ha JS, Bruchas MR, Rogers JA) Neuron 2017 Feb 08;93(3):509-521.e3 346 Citations |
| 1 | Evaluation of wrought Zn-Al alloys (1, 3, and 5 wt % Al) through mechanical and in vivo testing for stent applications. (Bowen PK, Seitz JM, Guillory RJ 2nd, Braykovich JP, Zhao S, Goldman J, Drelich JW) J Biomed Mater Res B Appl Biomater 2018 Jan;106(1):245-258 112 Citations |
| 1 | Effects of N-acetyl-seryl-asparyl-lysyl-proline on blood pressure, renal damage, and mortality in systemic lupus erythematosus. (Nakagawa P, Masjoan-Juncos JX, Basha H, Janic B, Worou ME, Liao TD, Romero CA, Peterson EL, Carretero OA) Physiol Rep 2017 Jan;5(2) 11 Citations |
| 1 | Accumbens nNOS Interneurons Regulate Cocaine Relapse. (Smith ACW, Scofield MD, Heinsbroek JA, Gipson CD, Neuhofer D, Roberts-Wolfe DJ, Spencer S, Garcia-Keller C, Stankeviciute NM, Smith RJ, Allen NP, Lorang MR, Griffin WC 3rd, Boger HA, Kalivas PW) J Neurosci 2017 Jan 25;37(4):742-756 78 Citations |
| 2 | Thiolate-based dinitrosyl iron complexes: Decomposition and detection and differentiation from S-nitrosothiols. (Keszler A, Diers AR, Ding Z, Hogg N) Nitric Oxide 2017 May 01;65:1-9 29 Citations |
| 1 | Modification of host dendritic cells by microchimerism-derived extracellular vesicles generates split tolerance. (Bracamonte-Baran W, Florentin J, Zhou Y, Jankowska-Gan E, Haynes WJ, Zhong W, Brennan TV, Dutta P, Claas FH, van Rood JJ, Burlingham WJ) Proc Natl Acad Sci U S A 2017 Jan 31;114(5):1099-1104 63 Citations |
| 3 | Cancer cell chemokines direct chemotaxis of activated stellate cells in pancreatic ductal adenocarcinoma. (Roy I, Boyle KA, Vonderhaar EP, Zimmerman NP, Gorse E, Mackinnon AC, Hwang RF, Franco-Barraza J, Cukierman E, Tsai S, Evans DB, Dwinell MB) Lab Invest 2017 Mar;97(3):302-317 28 Citations |
| 1 | Calsequestrin depolymerizes when calcium is depleted in the sarcoplasmic reticulum of working muscle. (Manno C, Figueroa LC, Gillespie D, Fitts R, Kang C, Franzini-Armstrong C, Rios E) Proc Natl Acad Sci U S A 2017 Jan 24;114(4):E638-E647 51 Citations |
| 1 | The PPE2 protein of Mycobacterium tuberculosis translocates to host nucleus and inhibits nitric oxide production. (Bhat KH, Srivastava S, Kotturu SK, Ghosh S, Mukhopadhyay S) Sci Rep 2017 Jan 10;7:39706 36 Citations |
| 1 | Network Dynamics Mediate Circadian Clock Plasticity. (Azzi A, Evans JA, Leise T, Myung J, Takumi T, Davidson AJ, Brown SA) Neuron 2017 Jan 18;93(2):441-450 56 Citations |
| 1 | The Nogo-B receptor promotes Ras plasma membrane localization and activation. (Zhao B, Hu W, Kumar S, Gonyo P, Rana U, Liu Z, Wang B, Duong WQ, Yang Z, Williams CL, Miao QR) Oncogene 2017 Jun 15;36(24):3406-3416 29 Citations |
| 1 | Inhibition and Degradation of Amyloid Beta (Aβ40) Fibrillation by Designed Small Peptide: A Combined Spectroscopy, Microscopy, and Cell Toxicity Study. (Ghosh A, Pradhan N, Bera S, Datta A, Krishnamoorthy J, Jana NR, Bhunia A) ACS Chem Neurosci 2017 Apr 19;8(4):718-722 48 Citations |
| 1 | The unfolded protein response mediates fibrogenesis and collagen I secretion through regulating TANGO1 in mice. (Maiers JL, Kostallari E, Mushref M, deAssuncao TM, Li H, Jalan-Sakrikar N, Huebert RC, Cao S, Malhi H, Shah VH) Hepatology 2017 Mar;65(3):983-998 81 Citations |
| 1 | Biocompatibility and bioactivity of porous polymer-derived Ca-Mg silicate ceramics. (Fiocco L, Li S, Stevens MM, Bernardo E, Jones JR) Acta Biomater 2017 Mar 01;50:56-67 61 Citations |
| 1 | Macrocyclic MEK1/2 inhibitor with efficacy in a mouse model of cardiomyopathy caused by lamin A/C gene mutation. (Wu W, Chordia MD, Hart BP, Kumarasinghe ES, Ji MK, Bhargava A, Lawlor MW, Shin JY, Sera F, Homma S, Muchir A, Khire UR, Worman HJ) Bioorg Med Chem 2017 Feb 01;25(3):1004-1013 21 Citations |
| 1 | Testing the Efficacy of Contrast-Enhanced Ultrasound in Detecting Transplant Rejection Using a Murine Model of Heart Transplantation. (Fischer K, Ohori S, Meral FC, Uehara M, Giannini S, Ichimura T, Smith RN, Jolesz FA, Guleria I, Zhang Y, White PJ, McDannold NJ, Hoffmeister K, Givertz MM, Abdi R) Am J Transplant 2017 Jul;17(7):1791-1801 14 Citations |
| 1 | TFEB ameliorates the impairment of the autophagy-lysosome pathway in neurons induced by doxorubicin. (Moruno-Manchon JF, Uzor NE, Kesler SR, Wefel JS, Townley DM, Nagaraja AS, Pradeep S, Mangala LS, Sood AK, Tsvetkov AS) Aging (Albany NY) 2016 Dec 16;8(12):3507-3519 48 Citations |
| 1 | Tgif1 and Tgif2 Repress Expression of the RabGAP Evi5l. (Anderson AE, Taniguchi K, Hao Y, Melhuish TA, Shah A, Turner SD, Sutherland AE, Wotton D) Mol Cell Biol 2017 Mar 01;37(5) 13 Citations |
| 2 | Hedgehog Signaling Overcomes an EZH2-Dependent Epigenetic Barrier to Promote Cholangiocyte Expansion. (Jalan-Sakrikar N, De Assuncao TM, Lu J, Almada LL, Lomberk G, Fernandez-Zapico ME, Urrutia R, Huebert RC) PLoS One 2016;11(12):e0168266 15 Citations |
| 2 | Synthesis and Characterization of a Novel γ-Aminobutyric Acid Type A (GABAA) Receptor Ligand That Combines Outstanding Metabolic Stability, Pharmacokinetics, and Anxiolytic Efficacy. (Poe MM, Methuku KR, Li G, Verma AR, Teske KA, Stafford DC, Arnold LA, Cramer JW, Jones TM, Cerne R, Krambis MJ, Witkin JM, Jambrina E, Rehman S, Ernst M, Cook JM, Schkeryantz JM) J Med Chem 2016 Dec 08;59(23):10800-10806 43 Citations |
| 1 | Molecular mechanism(s) involved in differential expression of vitamin C transporters along the intestinal tract. (Subramanian VS, Srinivasan P, Wildman AJ, Marchant JS, Said HM) Am J Physiol Gastrointest Liver Physiol 2017 Apr 01;312(4):G340-G347 25 Citations |
| 1 | Genetic and Molecular Analyses indicate independent effects of TGIFs on Nodal and Gli3 in neural tube patterning. (Taniguchi K, Anderson AE, Melhuish TA, Carlton AL, Manukyan A, Sutherland AE, Wotton D) Eur J Hum Genet 2017 Feb;25(2):208-215 16 Citations |
| 1 | In vitro characterization of SynthoPlate™ (synthetic platelet) technology and its in vivo evaluation in severely thrombocytopenic mice. (Shukla M, Sekhon UD, Betapudi V, Li W, Hickman DA, Pawlowski CL, Dyer MR, Neal MD, McCrae KR, Sen Gupta A) J Thromb Haemost 2017 Feb;15(2):375-387 55 Citations |
| 1 | Interferon-γ Limits Diabetogenic CD8+ T-Cell Effector Responses in Type 1 Diabetes. (Driver JP, Racine JJ, Ye C, Lamont DJ, Newby BN, Leeth CM, Chapman HD, Brusko TM, Chen YG, Mathews CE, Serreze DV) Diabetes 2017 Mar;66(3):710-721 26 Citations |
| 1 | Dickkopf-1 promotes hematopoietic regeneration via direct and niche-mediated mechanisms. (Himburg HA, Doan PL, Quarmyne M, Yan X, Sasine J, Zhao L, Hancock GV, Kan J, Pohl KA, Tran E, Chao NJ, Harris JR, Chute JP) Nat Med 2017 Jan;23(1):91-99 66 Citations |
| 2 | Hypothermia in mouse is caused by adenosine A1 and A3 receptor agonists and AMP via three distinct mechanisms. (Carlin JL, Jain S, Gizewski E, Wan TC, Tosh DK, Xiao C, Auchampach JA, Jacobson KA, Gavrilova O, Reitman ML) Neuropharmacology 2017 Mar 01;114:101-113 59 Citations |
| 1 | Acid Ceramidase Deficiency is characterized by a unique plasma cytokine and ceramide profile that is altered by therapy. (Dworski S, Lu P, Khan A, Maranda B, Mitchell JJ, Parini R, Di Rocco M, Hugle B, Yoshimitsu M, Magnusson B, Makay B, Arslan N, Guelbert N, Ehlert K, Jarisch A, Gardner-Medwin J, Dagher R, Terreri MT, Lorenco CM, Barillas-Arias L, Tanpaiboon P, Solyom A, Norris JS, He X, Schuchman EH, Levade T, Medin JA) Biochim Biophys Acta Mol Basis Dis 2017 Feb;1863(2):386-394 36 Citations |
| 2 | Optimization of substituted imidazobenzodiazepines as novel asthma treatments. (Jahan R, Stephen MR, Forkuo GS, Kodali R, Guthrie ML, Nieman AN, Yuan NY, Zahn NM, Poe MM, Li G, Yu OB, Yocum GT, Emala CW, Stafford DC, Cook JM, Arnold LA) Eur J Med Chem 2017 Jan 27;126:550-560 18 Citations |
| 2 | The Role of the Histone Methyltransferase Enhancer of Zeste Homolog 2 (EZH2) in the Pathobiological Mechanisms Underlying Inflammatory Bowel Disease (IBD). (Sarmento OF, Svingen PA, Xiong Y, Sun Z, Bamidele AO, Mathison AJ, Smyrk TC, Nair AA, Gonzalez MM, Sagstetter MR, Baheti S, McGovern DP, Friton JJ, Papadakis KA, Gautam G, Xavier RJ, Urrutia RA, Faubion WA) J Biol Chem 2017 Jan 13;292(2):706-722 58 Citations |
| 1 | Combined Inhibition of Both p110α and p110β Isoforms of Phosphatidylinositol 3-Kinase Is Required for Sustained Therapeutic Effect in PTEN-Deficient, ER+ Breast Cancer. (Hosford SR, Dillon LM, Bouley SJ, Rosati R, Yang W, Chen VS, Demidenko E, Morra RP Jr, Miller TW) Clin Cancer Res 2017 Jun 01;23(11):2795-2805 27 Citations |
| 1 | Phosphatidylinositol 3-kinase inhibition restores Ca2+ release defects and prolongs survival in myotubularin-deficient mice. (Kutchukian C, Lo Scrudato M, Tourneur Y, Poulard K, Vignaud A, Berthier C, Allard B, Lawlor MW, Buj-Bello A, Jacquemond V) Proc Natl Acad Sci U S A 2016 Dec 13;113(50):14432-14437 34 Citations |
| 1 | The Two-Component System ArlRS and Alterations in Metabolism Enable Staphylococcus aureus to Resist Calprotectin-Induced Manganese Starvation. (Radin JN, Kelliher JL, Párraga Solórzano PK, Kehl-Fie TE) PLoS Pathog 2016 Nov;12(11):e1006040 62 Citations |
| 1 | Stretchable multichannel antennas in soft wireless optoelectronic implants for optogenetics. (Park SI, Shin G, McCall JG, Al-Hasani R, Norris A, Xia L, Brenner DS, Noh KN, Bang SY, Bhatti DL, Jang KI, Kang SK, Mickle AD, Dussor G, Price TJ, Gereau RW 4th, Bruchas MR, Rogers JA) Proc Natl Acad Sci U S A 2016 Dec 13;113(50):E8169-E8177 124 Citations |
| 1 | CD98-Mediated Adhesive Signaling Enables the Establishment and Propagation of Acute Myelogenous Leukemia. (Bajaj J, Konuma T, Lytle NK, Kwon HY, Ablack JN, Cantor JM, Rizzieri D, Chuah C, Oehler VG, Broome EH, Ball ED, van der Horst EH, Ginsberg MH, Reya T) Cancer Cell 2016 Nov 14;30(5):792-805 84 Citations |
| 1 | Distinct cortical and striatal actions of a β-arrestin-biased dopamine D2 receptor ligand reveal unique antipsychotic-like properties. (Urs NM, Gee SM, Pack TF, McCorvy JD, Evron T, Snyder JC, Yang X, Rodriguiz RM, Borrelli E, Wetsel WC, Jin J, Roth BL, O'Donnell P, Caron MG) Proc Natl Acad Sci U S A 2016 Dec 13;113(50):E8178-E8186 112 Citations |
| 1 | Impact of the gut microbiota on enhancer accessibility in gut intraepithelial lymphocytes. (Semenkovich NP, Planer JD, Ahern PP, Griffin NW, Lin CY, Gordon JI) Proc Natl Acad Sci U S A 2016 Dec 20;113(51):14805-14810 35 Citations |
| 1 | Widespread recovery of methylation at gametic imprints in hypomethylated mouse stem cells following rescue with DNMT3A2. (Thakur A, Mackin SJ, Irwin RE, O'Neill KM, Pollin G, Walsh C) Epigenetics Chromatin 2016;9:53 6 Citations |
| 1 | TRPV4 ION Channel Is Associated with Scleroderma. (Goswami R, Cohen J, Sharma S, Zhang DX, Lafyatis R, Bhawan J, Rahaman SO) J Invest Dermatol 2017 Apr;137(4):962-965 28 Citations |
| 1 | Effects of a gut pathobiont in a gnotobiotic mouse model of childhood undernutrition. (Wagner VE, Dey N, Guruge J, Hsiao A, Ahern PP, Semenkovich NP, Blanton LV, Cheng J, Griffin N, Stappenbeck TS, Ilkayeva O, Newgard CB, Petri W, Haque R, Ahmed T, Gordon JI) Sci Transl Med 2016 Nov 23;8(366):366ra164 47 Citations |
| 1 | Cullin-3 mutation causes arterial stiffness and hypertension through a vascular smooth muscle mechanism. (Agbor LN, Ibeawuchi SC, Hu C, Wu J, Davis DR, Keen HL, Quelle FW, Sigmund CD) JCI Insight 2016 Nov 17;1(19):e91015 54 Citations |
| 1 | Wwox-Brca1 interaction: role in DNA repair pathway choice. (Schrock MS, Batar B, Lee J, Druck T, Ferguson B, Cho JH, Akakpo K, Hagrass H, Heerema NA, Xia F, Parvin JD, Aldaz CM, Huebner K) Oncogene 2017 Apr 20;36(16):2215-2227 38 Citations |
| 2 | Loss of free fatty acid receptor 2 enhances colonic adenoma development and reduces the chemopreventive effects of black raspberries in ApcMin/+ mice. (Pan P, W Skaer C, Wang HT, Oshima K, Huang YW, Yu J, Zhang J, M Yearsley M, A Agle K, R Drobyski W, Chen X, Wang LS) Carcinogenesis 2017 Jan;38(1):86-93 40 Citations |
| 1 | Undernourishment in utero and hepatic steatosis in later life: A potential issue in Japanese people. (Itoh H, Muramatsu-Kato K, Ferdous UJ, Kohmura-Kobayashi Y, Kanayama N) Congenit Anom (Kyoto) 2017 Nov;57(6):178-183 8 Citations |
| 1 | Hepatic Stellate Cell Selective Disruption of Dynamin-2 GTPase Increases Murine Fibrogenesis through Up-Regulation of Sphingosine-1 Phosphate-Induced Cell Migration. (Wang R, Ding Q, De Assuncao TM, Mounajjed T, Maiers JL, Dou C, Cao S, Yaqoob U, Huebert RC, Shah VH) Am J Pathol 2017 Jan;187(1):134-145 6 Citations |
| 1 | Genomic analyses identify recurrent MEF2D fusions in acute lymphoblastic leukaemia. (Gu Z, Churchman M, Roberts K, Li Y, Liu Y, Harvey RC, McCastlain K, Reshmi SC, Payne-Turner D, Iacobucci I, Shao Y, Chen IM, Valentine M, Pei D, Mungall KL, Mungall AJ, Ma Y, Moore R, Marra M, Stonerock E, Gastier-Foster JM, Devidas M, Dai Y, Wood B, Borowitz M, Larsen EE, Maloney K, Mattano LA Jr, Angiolillo A, Salzer WL, Burke MJ, Gianni F, Spinelli O, Radich JP, Minden MD, Moorman AV, Patel B, Fielding AK, Rowe JM, Luger SM, Bhatia R, Aldoss I, Forman SJ, Kohlschmidt J, Mrózek K, Marcucci G, Bloomfield CD, Stock W, Kornblau S, Kantarjian HM, Konopleva M, Paietta E, Willman CL, Loh ML, Hunger SP, Mullighan CG) Nat Commun 2016 Nov 08;7:13331 235 Citations |
| 2 | Lipid-Free Apolipoprotein A-I Reduces Progression of Atherosclerosis by Mobilizing Microdomain Cholesterol and Attenuating the Number of CD131 Expressing Cells: Monitoring Cholesterol Homeostasis Using the Cellular Ester to Total Cholesterol Ratio. (Kaul S, Xu H, Zabalawi M, Maruko E, Fulp BE, Bluemn T, Brzoza-Lewis KL, Gerelus M, Weerasekera R, Kallinger R, James R, Zhang YS, Thomas MJ, Sorci-Thomas MG) J Am Heart Assoc 2016 Nov 07;5(11) 20 Citations |
| 1 | Transgenic mouse model of IgM+ lymphoproliferative disease mimicking Waldenström macroglobulinemia. (Tompkins VS, Sompallae R, Rosean TR, Walsh S, Acevedo M, Kovalchuk AL, Han SS, Jing X, Holman C, Rehg JE, Herms S, Sunderland JS, Morse HC, Janz S) Blood Cancer J 2016 Nov 04;6(11):e488 3 Citations |
| 1 | Single residue AAV capsid mutation improves transduction of photoreceptors in the Abca4-/- mouse and bipolar cells in the rd1 mouse and human retina ex vivo. (De Silva SR, Charbel Issa P, Singh MS, Lipinski DM, Barnea-Cramer AO, Walker NJ, Barnard AR, Hankins MW, MacLaren RE) Gene Ther 2016 Nov;23(11):767-774 26 Citations |
| 1 | Role of CTGF in Sensitivity to Hyperthermia in Ovarian and Uterine Cancers. (Hatakeyama H, Wu SY, Lyons YA, Pradeep S, Wang W, Huang Q, Court KA, Liu T, Nie S, Rodriguez-Aguayo C, Shen F, Huang Y, Hisamatsu T, Mitamura T, Jennings N, Shim J, Dorniak PL, Mangala LS, Petrillo M, Petyuk VA, Schepmoes AA, Shukla AK, Torres-Lugo M, Lee JS, Rodland KD, Fagotti A, Lopez-Berestein G, Li C, Sood AK) Cell Rep 2016 Nov 01;17(6):1621-1631 22 Citations |
| 1 | Cardiac-deleterious role of galectin-3 in chronic angiotensin II-induced hypertension. (González GE, Rhaleb NE, D'Ambrosio MA, Nakagawa P, Liao TD, Peterson EL, Leung P, Dai X, Janic B, Liu YH, Yang XP, Carretero OA) Am J Physiol Heart Circ Physiol 2016 Nov 01;311(5):H1287-H1296 63 Citations |
| 2 | Harnessing bacteriocin biology as targeted therapy in the GI tract. (Kommineni S, Kristich CJ, Salzman NH) Gut Microbes 2016 Nov;7(6):512-517 16 Citations |
| 1 | Nervous System Expression of PPARγ and Mutant PPARγ Has Profound Effects on Metabolic Regulation and Brain Development. (Stump M, Guo DF, Lu KT, Mukohda M, Cassell MD, Norris AW, Rahmouni K, Sigmund CD) Endocrinology 2016 Nov;157(11):4266-4275 14 Citations |
| 1 | Cancer cells induce metastasis-supporting neutrophil extracellular DNA traps. (Park J, Wysocki RW, Amoozgar Z, Maiorino L, Fein MR, Jorns J, Schott AF, Kinugasa-Katayama Y, Lee Y, Won NH, Nakasone ES, Hearn SA, Küttner V, Qiu J, Almeida AS, Perurena N, Kessenbrock K, Goldberg MS, Egeblad M) Sci Transl Med 2016 Oct 19;8(361):361ra138 712 Citations |
| 1 | Phosphorylation of Translation Initiation Factor 2-Alpha in Leishmania donovani under Stress Is Necessary for Parasite Survival. (Abhishek K, Sardar AH, Das S, Kumar A, Ghosh AK, Singh R, Saini S, Mandal A, Verma S, Kumar A, Purkait B, Dikhit MR, Das P) Mol Cell Biol 2017 Jan 01;37(1) 16 Citations |
| 1 | Interferon Regulatory Factor 1 and Type I Interferon Cooperate To Control Acute Gammaherpesvirus Infection. (Mboko WP, Rekow MM, Ledwith MP, Lange PT, Schmitz KE, Anderson S, Tarakanova VL) J Virol 2017 Jan 01;91(1) 21 Citations |
| 1 | Congenic mapping identifies a novel Idd9 subregion regulating type 1 diabetes in NOD mice. (Lin B, Ciecko AE, MacKinney E, Serreze DV, Chen YG) Immunogenetics 2017 Mar;69(3):193-198 2 Citations |
| 1 | Circulating blood and platelets supply glycosyltransferases that enable extrinsic extracellular glycosylation. (Lee-Sundlov MM, Ashline DJ, Hanneman AJ, Grozovsky R, Reinhold VN, Hoffmeister KM, Lau JT) Glycobiology 2017 Jan;27(2):188-198 55 Citations |
| 2 | Stromal PTEN inhibits the expansion of mammary epithelial stem cells through Jagged-1. (Sizemore GM, Balakrishnan S, Hammer AM, Thies KA, Trimboli AJ, Wallace JA, Sizemore ST, Kladney RD, Woelke SA, Yu L, Fernandez SA, Chakravarti A, Leone G, Ostrowski MC) Oncogene 2017 Apr 20;36(16):2297-2308 22 Citations |
| 1 | E2F-2 Promotes Nuclear Condensation and Enucleation of Terminally Differentiated Erythroblasts. (Swartz KL, Wood SN, Murthy T, Ramirez O, Qin G, Pillai MM, Rao S, Minella AC) Mol Cell Biol 2017 Jan 01;37(1) 23 Citations |
| 2 | Role of Twist1 Phosphorylation in Angiogenesis and Pulmonary Fibrosis. (Mammoto T, Jiang A, Jiang E, Mammoto A) Am J Respir Cell Mol Biol 2016 Nov;55(5):633-644 40 Citations |
| 1 | Entry of Botulinum Neurotoxin Subtypes A1 and A2 into Neurons. (Kroken AR, Blum FC, Zuverink M, Barbieri JT) Infect Immun 2017 Jan;85(1) 29 Citations |
| 1 | Suppression of B-RafV600E melanoma cell survival by targeting mitochondria using triphenyl-phosphonium-conjugated nitroxide or ubiquinone. (Hong SK, Starenki D, Wu PK, Park JI) Cancer Biol Ther 2017 Feb;18(2):106-114 22 Citations |
| 1 | Adverse early life environment increases hippocampal microglia abundance in conjunction with decreased neural stem cells in juvenile mice. (Cohen S, Ke X, Liu Q, Fu Q, Majnik A, Lane R) Int J Dev Neurosci 2016 Dec;55:56-65 27 Citations |
| 1 | Growth and maturation of heart valves leads to changes in endothelial cell distribution, impaired function, decreased metabolism and reduced cell proliferation. (Anstine LJ, Bobba C, Ghadiali S, Lincoln J) J Mol Cell Cardiol 2016 Nov;100:72-82 30 Citations |
| 1 | Neuronal protection against oxidative insult by polyanhydride nanoparticle-based mitochondria-targeted antioxidant therapy. (Brenza TM, Ghaisas S, Ramirez JEV, Harischandra D, Anantharam V, Kalyanaraman B, Kanthasamy AG, Narasimhan B) Nanomedicine 2017 Apr;13(3):809-820 84 Citations |
| 1 | A novel TRPV4-specific agonist inhibits monocyte adhesion and atherosclerosis. (Xu S, Liu B, Yin M, Koroleva M, Mastrangelo M, Ture S, Morrell CN, Zhang DX, Fisher EA, Jin ZG) Oncotarget 2016 Jun 21;7(25):37622-37635 61 Citations |
| 3 | On the use of peroxy-caged luciferin (PCL-1) probe for bioluminescent detection of inflammatory oxidants in vitro and in vivo - Identification of reaction intermediates and oxidant-specific minor products. (Zielonka J, Podsiadły R, Zielonka M, Hardy M, Kalyanaraman B) Free Radic Biol Med 2016 Oct;99:32-42 44 Citations |
| 1 | A Modified Polysaccharide-Based Hydrogel for Enhanced Osteogenic Maturation and Mineralization Independent of Differentiation Factors. (Sanyasi S, Kumar S, Ghosh A, Majhi RK, Kaur N, Choudhury P, Singh UP, Goswami C, Goswami L) Macromol Biosci 2017 Mar;17(3) 19 Citations |
| 1 | Nogo-B receptor deficiency increases liver X receptor alpha nuclear translocation and hepatic lipogenesis through an adenosine monophosphate-activated protein kinase alpha-dependent pathway. (Hu W, Zhang W, Chen Y, Rana U, Teng RJ, Duan Y, Liu Z, Zhao B, Foeckler J, Weiler H, Kallinger RE, Thomas MJ, Zhang K, Han J, Miao QR) Hepatology 2016 Nov;64(5):1559-1576 31 Citations |
| 1 | Depletion of Tip60 from In Vivo Cardiomyocytes Increases Myocyte Density, Followed by Cardiac Dysfunction, Myocyte Fallout and Lethality. (Fisher JB, Horst A, Wan T, Kim MS, Auchampach J, Lough J) PLoS One 2016;11(10):e0164855 16 Citations |
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| 2 | Selective Deletion of the Brain-Specific Isoform of Renin Causes Neurogenic Hypertension. (Shinohara K, Liu X, Morgan DA, Davis DR, Sequeira-Lopez ML, Cassell MD, Grobe JL, Rahmouni K, Sigmund CD) Hypertension 2016 Dec;68(6):1385-1392 45 Citations |
| 1 | Super-Enhancers at the Nanog Locus Differentially Regulate Neighboring Pluripotency-Associated Genes. (Blinka S, Reimer MH Jr, Pulakanti K, Rao S) Cell Rep 2016 Sep 27;17(1):19-28 80 Citations |
| 1 | Mice lacking sialyltransferase ST3Gal-II develop late-onset obesity and insulin resistance. (Lopez PH, Aja S, Aoki K, Seldin MM, Lei X, Ronnett GV, Wong GW, Schnaar RL) Glycobiology 2017 Jan;27(2):129-139 23 Citations |
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| 1 | Staphylococcus aureus α-Toxin Response Distinguishes Respiratory Virus-Methicillin-Resistant S. aureus Coinfection in Children. (Yu KO, Randolph AG, Agan AA, Yip WK, Truemper EJ, Weiss SL, Ackerman KG, Schwarz AJ, Giuliano JS Jr, Hall MW, Bubeck Wardenburg J, Pediatric Acute Lung Injury and Sepsis Investigators (PALISI) PICFlu Study Group, PALISI PICFlu Study Group) J Infect Dis 2016 Dec 01;214(11):1638-1646 17 Citations |
| 1 | Antitumor and Antiangiogenic Effects of Aspirin-PC in Ovarian Cancer. (Huang Y, Lichtenberger LM, Taylor M, Bottsford-Miller JN, Haemmerle M, Wagner MJ, Lyons Y, Pradeep S, Hu W, Previs RA, Hansen JM, Fang D, Dorniak PL, Filant J, Dial EJ, Shen F, Hatakeyama H, Sood AK) Mol Cancer Ther 2016 Dec;15(12):2894-2904 44 Citations |
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| 1 | Genetic ablation of Smoothened in pancreatic fibroblasts increases acinar-ductal metaplasia. (Liu X, Pitarresi JR, Cuitiño MC, Kladney RD, Woelke SA, Sizemore GM, Nayak SG, Egriboz O, Schweickert PG, Yu L, Trela S, Schilling DJ, Halloran SK, Li M, Dutta S, Fernandez SA, Rosol TJ, Lesinski GB, Shakya R, Ludwig T, Konieczny SF, Leone G, Wu J, Ostrowski MC) Genes Dev 2016 Sep 01;30(17):1943-55 49 Citations |
| 1 | Metastatic progression is associated with dynamic changes in the local microenvironment. (Aiello NM, Bajor DL, Norgard RJ, Sahmoud A, Bhagwat N, Pham MN, Cornish TC, Iacobuzio-Donahue CA, Vonderheide RH, Stanger BZ) Nat Commun 2016 Sep 15;7:12819 106 Citations |
| 2 | Corticosterone Potentiation of Cocaine-Induced Reinstatement of Conditioned Place Preference in Mice is Mediated by Blockade of the Organic Cation Transporter 3. (McReynolds JR, Taylor A, Vranjkovic O, Ambrosius T, Derricks O, Nino B, Kurtoglu B, Wheeler RA, Baker DA, Gasser PJ, Mantsch JR) Neuropsychopharmacology 2017 Feb;42(3):757-765 23 Citations |
| 2 | Effects of Donor Vitamin A Deficiency and Pharmacologic Modulation of Donor T Cell Retinoic Acid Pathway on the Severity of Experimental Graft-versus-Host Disease. (Dodge J, Stephans A, Lai J, Drobyski WR, Chen X) Biol Blood Marrow Transplant 2016 Dec;22(12):2141-2148 8 Citations |
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| 1 | Structure-based discovery of opioid analgesics with reduced side effects. (Manglik A, Lin H, Aryal DK, McCorvy JD, Dengler D, Corder G, Levit A, Kling RC, Bernat V, Hübner H, Huang XP, Sassano MF, Giguère PM, Löber S, Da Duan, Scherrer G, Kobilka BK, Gmeiner P, Roth BL, Shoichet BK) Nature 2016 Sep 08;537(7619):185-190 750 Citations |
| 1 | Superagonist, Full Agonist, Partial Agonist, and Antagonist Actions of Arylguanidines at 5-Hydroxytryptamine-3 (5-HT3) Subunit A Receptors. (Alix K, Khatri S, Mosier PD, Casterlow S, Yan D, Nyce HL, White MM, Schulte MK, Dukat M) ACS Chem Neurosci 2016 Nov 16;7(11):1565-1574 11 Citations |
| 1 | Structural Elucidation of the Cell-Penetrating Penetratin Peptide in Model Membranes at the Atomic Level: Probing Hydrophobic Interactions in the Blood-Brain Barrier. (Bera S, Kar RK, Mondal S, Pahan K, Bhunia A) Biochemistry 2016 Sep 06;55(35):4982-96 25 Citations |
| 1 | Retinal Hypercholesterolemia Triggers Cholesterol Accumulation and Esterification in Photoreceptor Cells. (Saadane A, Mast N, Dao T, Ahmad B, Pikuleva IA) J Biol Chem 2016 Sep 23;291(39):20427-39 25 Citations |
| 1 | Obesity alters immune and metabolic profiles: New insight from obese-resistant mice on high-fat diet. (Boi SK, Buchta CM, Pearson NA, Francis MB, Meyerholz DK, Grobe JL, Norian LA) Obesity (Silver Spring) 2016 Oct;24(10):2140-9 54 Citations |
| 1 | Loss-of-function mutations in the RNA biogenesis factor NAF1 predispose to pulmonary fibrosis-emphysema. (Stanley SE, Gable DL, Wagner CL, Carlile TM, Hanumanthu VS, Podlevsky JD, Khalil SE, DeZern AE, Rojas-Duran MF, Applegate CD, Alder JK, Parry EM, Gilbert WV, Armanios M) Sci Transl Med 2016 Aug 10;8(351):351ra107 170 Citations |
| 4 | A colitogenic memory CD4+ T cell population mediates gastrointestinal graft-versus-host disease. (Zhou V, Agle K, Chen X, Beres A, Komorowski R, Belle L, Taylor C, Zhu F, Haribhai D, Williams CB, Verbsky J, Blumenschein W, Sadekova S, Bowman E, Ballantyne C, Weaver C, Serody DA, Vincent B, Serody J, Cua DJ, Drobyski WR) J Clin Invest 2016 Sep 01;126(9):3541-55 26 Citations |
| 1 | Targeting factor VIII expression to platelets for hemophilia A gene therapy does not induce an apparent thrombotic risk in mice. (Baumgartner CK, Mattson JG, Weiler H, Shi Q, Montgomery RR) J Thromb Haemost 2017 Jan;15(1):98-109 18 Citations |
| 2 | Blockade of interleukin-27 signaling reduces GVHD in mice by augmenting Treg reconstitution and stabilizing Foxp3 expression. (Belle L, Agle K, Zhou V, Yin-Yuan C, Komorowski R, Eastwood D, Logan B, Sun J, Ghilardi N, Cua D, Williams CB, Gaignage M, Marillier R, van Snick J, Drobyski WR) Blood 2016 Oct 20;128(16):2068-2082 37 Citations |
| 1 | Aged Human Stored Red Blood Cell Supernatant Inhibits Macrophage Phagocytosis in an HMGB1 Dependent Manner After Trauma in a Murine Model. (Zettel KR, Dyer M, Raval JS, Wu X, Klune JR, Gutierrez A, Triulzi DJ, Billiar TR, Neal MD) Shock 2017 Feb;47(2):217-224 11 Citations |
| 1 | Loss of ABCG1 influences regulatory T cell differentiation and atherosclerosis. (Cheng HY, Gaddis DE, Wu R, McSkimming C, Haynes LD, Taylor AM, McNamara CA, Sorci-Thomas M, Hedrick CC) J Clin Invest 2016 Sep 01;126(9):3236-46 63 Citations |
| 1 | Salt-Inducible Kinase 2 Couples Ovarian Cancer Cell Metabolism with Survival at the Adipocyte-Rich Metastatic Niche. (Miranda F, Mannion D, Liu S, Zheng Y, Mangala LS, Redondo C, Herrero-Gonzalez S, Xu R, Taylor C, Chedom DF, Carrami EM, Albukhari A, Jiang D, Pradeep S, Rodriguez-Aguayo C, Lopez-Berestein G, Salah E, Abdul Azeez KR, Elkins JM, Campo L, Myers KA, Klotz D, Bivona S, Dhar S, Bast RC Jr, Saya H, Choi HG, Gray NS, Fischer R, Kessler BM, Yau C, Sood AK, Motohara T, Knapp S, Ahmed AA) Cancer Cell 2016 Aug 08;30(2):273-289 145 Citations |
| 1 | Coordination of signaling and tissue mechanics during morphogenesis of murine intestinal villi: a role for mitotic cell rounding. (Freddo AM, Shoffner SK, Shao Y, Taniguchi K, Grosse AS, Guysinger MN, Wang S, Rudraraju S, Margolis B, Garikipati K, Schnell S, Gumucio DL) Integr Biol (Camb) 2016 Sep 12;8(9):918-28 36 Citations |
| 1 | Collecting Duct Renin Does Not Mediate DOCA-Salt Hypertension or Renal Injury. (Song K, Stuart D, Abraham N, Wang F, Wang S, Yang T, Sigmund CD, Kohan DE, Ramkumar N) PLoS One 2016;11(7):e0159872 13 Citations |
| 1 | Synergistic functions of E2F7 and E2F8 are critical to suppress stress-induced skin cancer. (Thurlings I, Martínez-López LM, Westendorp B, Zijp M, Kuiper R, Tooten P, Kent LN, Leone G, Vos HJ, Burgering B, de Bruin A) Oncogene 2017 Feb 09;36(6):829-839 54 Citations |
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| 1 | Sperm-associated antigen 9 (SPAG9) promotes the survival and tumor growth of triple-negative breast cancer cells. (Jagadish N, Gupta N, Agarwal S, Parashar D, Sharma A, Fatima R, Topno AP, Kumar V, Suri A) Tumour Biol 2016 Oct;37(10):13101-13110 20 Citations |
| 1 | Development and Validation of a Small Animal Immobilizer and Positioning System for the Study of Delivery of Intracranial and Extracranial Radiotherapy Using the Gamma Knife System. (Awan MJ, Dorth J, Mani A, Kim H, Zheng Y, Mislmani M, Welford S, Yuan J, Wessels BW, Lo SS, Letterio J, Machtay M, Sloan A, Sohn JW) Technol Cancer Res Treat 2017 Apr;16(2):203-210 5 Citations |
| 1 | Potential cerebral malaria therapy: intramuscular arteether and vitamin D co-administration. (Dwivedi H, Singh SK, Chauhan BS, Gunjan S, Tripathi R) Parasitology 2016 Oct;143(12):1557-68 14 Citations |
| 2 | The pancreatitis-associated protein VMP1, a key regulator of inducible autophagy, promotes Kras(G12D)-mediated pancreatic cancer initiation. (Loncle C, Molejon MI, Lac S, Tellechea JI, Lomberk G, Gramatica L, Fernandez Zapico MF, Dusetti N, Urrutia R, Iovanna JL) Cell Death Dis 2016 Jul 14;7(7):e2295 30 Citations |
| 1 | Stat5 is critical for the development and maintenance of myeloproliferative neoplasm initiated by Nf1 deficiency. (Sachs Z, Been RA, DeCoursin KJ, Nguyen HT, Mohd Hassan NA, Noble-Orcutt KE, Eckfeldt CE, Pomeroy EJ, Diaz-Flores E, Geurts JL, Diers MD, Hasz DE, Morgan KJ, MacMillan ML, Shannon KM, Largaespada DA, Wiesner SM) Haematologica 2016 Oct;101(10):1190-1199 16 Citations |
| 2 | Optimization of Morpholino Antisense Oligonucleotides Targeting the Intronic Repressor Element1 in Spinal Muscular Atrophy. (Osman EY, Washington CW 3rd, Kaifer KA, Mazzasette C, Patitucci TN, Florea KM, Simon ME, Ko CP, Ebert AD, Lorson CL) Mol Ther 2016 Sep;24(9):1592-601 30 Citations |
| 1 | Novel Roles and Mechanism for Krüppel-like Factor 16 (KLF16) Regulation of Neurite Outgrowth and Ephrin Receptor A5 (EphA5) Expression in Retinal Ganglion Cells. (Wang J, Galvao J, Beach KM, Luo W, Urrutia RA, Goldberg JL, Otteson DC) J Biol Chem 2016 Aug 26;291(35):18084-95 18 Citations |
| 1 | The eicosanoids leukotriene D4 and prostaglandin E2 promote the tumorigenicity of colon cancer-initiating cells in a xenograft mouse model. (Bellamkonda K, Chandrashekar NK, Osman J, Selvanesan BC, Savari S, Sjölander A) BMC Cancer 2016 Jul 07;16:425 26 Citations |
| 1 | A Molecular Profile of the Endothelial Cell Response to Ionizing Radiation. (Himburg HA, Sasine J, Yan X, Kan J, Dressman H, Chute JP) Radiat Res 2016 Aug;186(2):141-52 27 Citations |
| 1 | Characterization of Fatty Acid Binding Protein 7 (FABP7) in the Murine Retina. (Su X, Tan QS, Parikh BH, Tan A, Mehta MN, Sia Wey Y, Tun SB, Li LJ, Han XY, Wong TY, Hunziker W, Luu CD, Owada Y, Barathi VA, Zhang SS, Chaurasia SS) Invest Ophthalmol Vis Sci 2016 Jun 01;57(7):3397-408 17 Citations |
| 1 | Thrombolysis by chemically modified coagulation factor Xa. (Pryzdial EL, Meixner SC, Talbot K, Eltringham-Smith LJ, Baylis JR, Lee FM, Kastrup CJ, Sheffield WP) J Thromb Haemost 2016 Sep;14(9):1844-54 6 Citations |
| 1 | Heat Shock Factor 1 Is a Substrate for p38 Mitogen-Activated Protein Kinases. (Dayalan Naidu S, Sutherland C, Zhang Y, Risco A, de la Vega L, Caunt CJ, Hastie CJ, Lamont DJ, Torrente L, Chowdhry S, Benjamin IJ, Keyse SM, Cuenda A, Dinkova-Kostova AT) Mol Cell Biol 2016 Sep 15;36(18):2403-17 59 Citations |
| 1 | Efficacy and Mechanism of Action of Low Dose Emetine against Human Cytomegalovirus. (Mukhopadhyay R, Roy S, Venkatadri R, Su YP, Ye W, Barnaeva E, Mathews Griner L, Southall N, Hu X, Wang AQ, Xu X, Dulcey AE, Marugan JJ, Ferrer M, Arav-Boger R) PLoS Pathog 2016 Jun;12(6):e1005717 54 Citations |
| 1 | New Insights into Mechanisms and Functions of Chemokine (C-X-C Motif) Receptor 4 Heteromerization in Vascular Smooth Muscle. (Evans AE, Tripathi A, LaPorte HM, Brueggemann LI, Singh AK, Albee LJ, Byron KL, Tarasova NI, Volkman BF, Cho TY, Gaponenko V, Majetschak M) Int J Mol Sci 2016 Jun 20;17(5) 31 Citations |
| 1 | First In Vivo Testing of Compounds Targeting Group 3 Medulloblastomas Using an Implantable Microdevice as a New Paradigm for Drug Development. (Jonas O, Calligaris D, Methuku KR, Poe MM, Francois JP, Tranghese F, Changelian A, Sieghart W, Ernst M, Krummel DA, Cook JM, Pomeroy SL, Cima M, Agar NY, Langer R, Sengupta S) J Biomed Nanotechnol 2016 Jun;12(6):1297-302 40 Citations |
| 1 | Potentiation of antimalarial activity of arteether in combination with Vetiver root extract. (Dhawan S, Gunjan S, Pal A, Tripathi R) Indian J Exp Biol 2016 May;54(5):315-21 3 Citations |
| 1 | Fatty acid amide hydrolase inhibition for the symptomatic relief of Parkinson's disease. (Celorrio M, Fernández-Suárez D, Rojo-Bustamante E, Echeverry-Alzate V, Ramírez MJ, Hillard CJ, López-Moreno JA, Maldonado R, Oyarzábal J, Franco R, Aymerich MS) Brain Behav Immun 2016 Oct;57:94-105 57 Citations |
| 1 | Merestinib blocks Mnk kinase activity in acute myeloid leukemia progenitors and exhibits antileukemic effects in vitro and in vivo. (Kosciuczuk EM, Saleiro D, Kroczynska B, Beauchamp EM, Eckerdt F, Blyth GT, Abedin SM, Giles FJ, Altman JK, Platanias LC) Blood 2016 Jul 21;128(3):410-4 43 Citations |
| 1 | Genome-wide characterization of human L1 antisense promoter-driven transcripts. (Criscione SW, Theodosakis N, Micevic G, Cornish TC, Burns KH, Neretti N, Rodić N) BMC Genomics 2016 Jun 14;17:463 57 Citations |
| 1 | Pancreatic β-Cells From Mice Offset Age-Associated Mitochondrial Deficiency With Reduced KATP Channel Activity. (Gregg T, Poudel C, Schmidt BA, Dhillon RS, Sdao SM, Truchan NA, Baar EL, Fernandez LA, Denu JM, Eliceiri KW, Rogers JD, Kimple ME, Lamming DW, Merrins MJ) Diabetes 2016 Sep;65(9):2700-10 59 Citations |
| 1 | Image-based detection and targeting of therapy resistance in pancreatic adenocarcinoma. (Fox RG, Lytle NK, Jaquish DV, Park FD, Ito T, Bajaj J, Koechlein CS, Zimdahl B, Yano M, Kopp J, Kritzik M, Sicklick J, Sander M, Grandgenett PM, Hollingsworth MA, Shibata S, Pizzo D, Valasek M, Sasik R, Scadeng M, Okano H, Kim Y, MacLeod AR, Lowy AM, Reya T) Nature 2016 Jun 16;534(7607):407-411 118 Citations |
| 1 | A novel CBL-Bflox/flox mouse model allows tissue-selective fully conditional CBL/CBL-B double-knockout: CD4-Cre mediated CBL/CBL-B deletion occurs in both T-cells and hematopoietic stem cells. (Goetz B, An W, Mohapatra B, Zutshi N, Iseka F, Storck MD, Meza J, Sheinin Y, Band V, Band H) Oncotarget 2016 Aug 09;7(32):51107-51123 11 Citations |
| 3 | E-cadherin re-expression shows in vivo evidence for mesenchymal to epithelial transition in clonal metastatic breast tumor cells. (Palen K, Weber J, Dwinell MB, Johnson BD, Ramchandran R, Gershan JA) Oncotarget 2016 Jul 12;7(28):43363-43375 21 Citations |
| 1 | Responses to drugs of abuse and non-drug rewards in leptin deficient ob/ob mice. (Muelbl MJ, Nawarawong NN, Clancy PT, Nettesheim CE, Lim YW, Olsen CM) Psychopharmacology (Berl) 2016 Jul;233(14):2799-811 22 Citations |
| 1 | Mouse model of MYD88L265P-dependent DLBCL. (Janz S) Blood 2016 Jun 02;127(22):2660-1 1 Citation |
| 1 | Assessment of hepatoprotective and nephroprotective potential of withaferin A on bromobenzene-induced injury in Swiss albino mice: possible involvement of mitochondrial dysfunction and inflammation. (Vedi M, Sabina EP) Cell Biol Toxicol 2016 Oct;32(5):373-90 39 Citations |
| 2 | mTORC1 Signaling Contributes to Drinking But Not Blood Pressure Responses to Brain Angiotensin II. (Muta K, Morgan DA, Grobe JL, Sigmund CD, Rahmouni K) Endocrinology 2016 Aug;157(8):3140-8 10 Citations |
| 1 | Dynamin 1- and 3-Mediated Endocytosis Is Essential for the Development of a Large Central Synapse In Vivo. (Fan F, Funk L, Lou X) J Neurosci 2016 Jun 01;36(22):6097-115 36 Citations |
| 1 | Characterization of Eicosanoids Produced by Adipocyte Lipolysis: IMPLICATION OF CYCLOOXYGENASE-2 IN ADIPOSE INFLAMMATION. (Gartung A, Zhao J, Chen S, Mottillo E, VanHecke GC, Ahn YH, Maddipati KR, Sorokin A, Granneman J, Lee MJ) J Biol Chem 2016 Jul 29;291(31):16001-10 44 Citations |
| 1 | TWIST1 Integrates Endothelial Responses to Flow in Vascular Dysfunction and Atherosclerosis. (Mahmoud MM, Kim HR, Xing R, Hsiao S, Mammoto A, Chen J, Serbanovic-Canic J, Feng S, Bowden NP, Maguire R, Ariaans M, Francis SE, Weinberg PD, van der Heiden K, Jones EA, Chico TJ, Ridger V, Evans PC) Circ Res 2016 Jul 22;119(3):450-62 118 Citations |
| 1 | Immunotherapy with iTreg and nTreg Cells in a Murine Model of Inflammatory Bowel Disease. (Haribhai D, Chatila TA, Williams CB) Methods Mol Biol 2016;1422:197-211 23 Citations |
| 1 | PIAS1 Promotes Lymphomagenesis through MYC Upregulation. (Rabellino A, Melegari M, Tompkins VS, Chen W, Van Ness BG, Teruya-Feldstein J, Conacci-Sorrell M, Janz S, Scaglioni PP) Cell Rep 2016 Jun 07;15(10):2266-2278 37 Citations |
| 1 | Pyrrolidine-Acridine hybrid in Artemisinin-based combination: a pharmacodynamic study. (Pandey SK, Biswas S, Gunjan S, Chauhan BS, Singh SK, Srivastava K, Singh S, Batra S, Tripathi R) Parasitology 2016 Sep;143(11):1421-32 7 Citations |
| 1 | Optogenetic Interrogation of Functional Synapse Formation by Corticospinal Tract Axons in the Injured Spinal Cord. (Jayaprakash N, Wang Z, Hoeynck B, Krueger N, Kramer A, Balle E, Wheeler DS, Wheeler RA, Blackmore MG) J Neurosci 2016 May 25;36(21):5877-90 43 Citations |
| 1 | Inhibition of myeloperoxidase oxidant production by N-acetyl lysyltyrosylcysteine amide reduces brain damage in a murine model of stroke. (Yu G, Liang Y, Huang Z, Jones DW, Pritchard KA Jr, Zhang H) J Neuroinflammation 2016 May 24;13(1):119 58 Citations |
| 6 | Mitochondria-Targeted Analogues of Metformin Exhibit Enhanced Antiproliferative and Radiosensitizing Effects in Pancreatic Cancer Cells. (Cheng G, Zielonka J, Ouari O, Lopez M, McAllister D, Boyle K, Barrios CS, Weber JJ, Johnson BD, Hardy M, Dwinell MB, Kalyanaraman B) Cancer Res 2016 Jul 01;76(13):3904-15 167 Citations |
| 1 | Effect of selective expression of dominant-negative PPARγ in pro-opiomelanocortin neurons on the control of energy balance. (Stump M, Guo DF, Lu KT, Mukohda M, Liu X, Rahmouni K, Sigmund CD) Physiol Genomics 2016 Jul 01;48(7):491-501 14 Citations |
| 3 | Nitric Oxide Suppresses β-Cell Apoptosis by Inhibiting the DNA Damage Response. (Oleson BJ, Broniowska KA, Naatz A, Hogg N, Tarakanova VL, Corbett JA) Mol Cell Biol 2016 Aug 01;36(15):2067-77 39 Citations |
| 1 | [Mutation Induction in the Mouse and Human Germline]. (Dubrova YE) Genetika 2016 Jan;52(1):24-36 2 Citations |
| 1 | Tissue-specific dynamin-1 deletion at the calyx of Held decreases short-term depression through a mechanism distinct from vesicle resupply. (Mahapatra S, Fan F, Lou X) Proc Natl Acad Sci U S A 2016 May 31;113(22):E3150-8 16 Citations |
| 1 | Tgif1 and Tgif2 Regulate Axial Patterning in Mouse. (Melhuish TA, Taniguchi K, Wotton D) PLoS One 2016;11(5):e0155837 8 Citations |
| 2 | A Miniaturized Screen of a Schistosoma mansoni Serotonergic G Protein-Coupled Receptor Identifies Novel Classes of Parasite-Selective Inhibitors. (Chan JD, McCorvy JD, Acharya S, Johns ME, Day TA, Roth BL, Marchant JS) PLoS Pathog 2016 May;12(5):e1005651 30 Citations |
| 2 | Inhibition of local estrogen synthesis in the hippocampus impairs hippocampal memory consolidation in ovariectomized female mice. (Tuscher JJ, Szinte JS, Starrett JR, Krentzel AA, Fortress AM, Remage-Healey L, Frick KM) Horm Behav 2016 Jul;83:60-67 111 Citations |
| 1 | Branched Peptide, B2088, Disrupts the Supramolecular Organization of Lipopolysaccharides and Sensitizes the Gram-negative Bacteria. (Lakshminarayanan R, Tan WX, Aung TT, Goh ET, Muruganantham N, Li J, Chang JY, Dikshit N, Saraswathi P, Lim RR, Kang TS, Balamuralidhar V, Sukumaran B, Verma CS, Sivaraman J, Chaurasia SS, Liu S, Beuerman RW) Sci Rep 2016 May 13;6:25905 25 Citations |
| 1 | Thrombospondin-4 divergently regulates voltage-gated Ca2+ channel subtypes in sensory neurons after nerve injury. (Pan B, Guo Y, Wu HE, Park J, Trinh VN, Luo ZD, Hogan QH) Pain 2016 Sep;157(9):2068-2080 31 Citations |
| 1 | Mouse Models for Studying Depression-Like States and Antidepressant Drugs. (Bergner CL, Smolinsky AN, Hart PC, Dufour BD, Egan RJ, LaPorte JL, Kalueff AV) Methods Mol Biol 2016;1438:255-69 8 Citations |
| 1 | Experimental Models of Anxiety for Drug Discovery and Brain Research. (Hart PC, Bergner CL, Smolinsky AN, Dufour BD, Egan RJ, LaPorte JL, Kalueff AV) Methods Mol Biol 2016;1438:271-91 17 Citations |
| 1 | Loss of CENP-F results in distinct microtubule-related defects without chromosomal abnormalities. (Pfaltzgraff ER, Roth GM, Miller PM, Gintzig AG, Ohi R, Bader DM) Mol Biol Cell 2016 Jul 01;27(13):1990-9 13 Citations |
| 1 | Adhesion of Blood Clots Can Be Enhanced When Copolymerized with a Macromer That Is Crosslinked by Coagulation Factor XIIIa. (Chan KY, Zhao C, Siren EM, Chan JC, Boschman J, Kastrup CJ) Biomacromolecules 2016 Jun 13;17(6):2248-52 13 Citations |
| 1 | Arginase-1 is expressed exclusively by infiltrating myeloid cells in CNS injury and disease. (Greenhalgh AD, Passos Dos Santos R, Zarruk JG, Salmon CK, Kroner A, David S) Brain Behav Immun 2016 Aug;56:61-7 57 Citations |
| 2 | Epac Signaling Is Required for Cocaine-Induced Change in AMPA Receptor Subunit Composition in the Ventral Tegmental Area. (Liu X, Chen Y, Tong J, Reynolds AM, Proudfoot SC, Qi J, Penzes P, Lu Y, Liu QS) J Neurosci 2016 Apr 27;36(17):4802-15 22 Citations |
| 2 | Development of GABAA Receptor Subtype-Selective Imidazobenzodiazepines as Novel Asthma Treatments. (Forkuo GS, Guthrie ML, Yuan NY, Nieman AN, Kodali R, Jahan R, Stephen MR, Yocum GT, Treven M, Poe MM, Li G, Yu OB, Hartzler BD, Zahn NM, Ernst M, Emala CW, Stafford DC, Cook JM, Arnold LA) Mol Pharm 2016 Jun 06;13(6):2026-38 28 Citations |
| 1 | Circulating Differentially Methylated Amylin DNA as a Biomarker of β-Cell Loss in Type 1 Diabetes. (Olsen JA, Kenna LA, Spelios MG, Hessner MJ, Akirav EM) PLoS One 2016;11(4):e0152662 47 Citations |
| 3 | Treatment with ActRIIB-mFc Produces Myofiber Growth and Improves Lifespan in the Acta1 H40Y Murine Model of Nemaline Myopathy. (Tinklenberg J, Meng H, Yang L, Liu F, Hoffmann RG, Dasgupta M, Allen KP, Beggs AH, Hardeman EC, Pearsall RS, Fitts RH, Lawlor MW) Am J Pathol 2016 Jun;186(6):1568-81 22 Citations |
| 1 | A splice variant of the myosin phosphatase regulatory subunit tunes arterial reactivity and suppresses response to salt loading. (Reho JJ, Kenchegowda D, Asico LD, Fisher SA) Am J Physiol Heart Circ Physiol 2016 Jun 01;310(11):H1715-24 10 Citations |
| 1 | Intracellular Trafficking, Localization, and Mobilization of Platelet-Borne Thiol Isomerases. (Crescente M, Pluthero FG, Li L, Lo RW, Walsh TG, Schenk MP, Holbrook LM, Louriero S, Ali MS, Vaiyapuri S, Falet H, Jones IM, Poole AW, Kahr WH, Gibbins JM) Arterioscler Thromb Vasc Biol 2016 Jun;36(6):1164-73 53 Citations |
| 1 | Craniofacial tissue oxygen saturation is associated with blood pH using an examiner's finger-mounted tissue oximetry in mice. (Uchida T, Kanayama N, Kawai K, Niwayama M) J Biomed Opt 2016 Apr 30;21(4):40502 11 Citations |
| 1 | X-ray laser diffraction for structure determination of the rhodopsin-arrestin complex. (Zhou XE, Gao X, Barty A, Kang Y, He Y, Liu W, Ishchenko A, White TA, Yefanov O, Han GW, Xu Q, de Waal PW, Suino-Powell KM, Boutet S, Williams GJ, Wang M, Li D, Caffrey M, Chapman HN, Spence JC, Fromme P, Weierstall U, Stevens RC, Cherezov V, Melcher K, Xu HE) Sci Data 2016 Apr 12;3:160021 46 Citations |
| 1 | FAK regulates platelet extravasation and tumor growth after antiangiogenic therapy withdrawal. (Haemmerle M, Bottsford-Miller J, Pradeep S, Taylor ML, Choi HJ, Hansen JM, Dalton HJ, Stone RL, Cho MS, Nick AM, Nagaraja AS, Gutschner T, Gharpure KM, Mangala LS, Rupaimoole R, Han HD, Zand B, Armaiz-Pena GN, Wu SY, Pecot CV, Burns AR, Lopez-Berestein G, Afshar-Kharghan V, Sood AK) J Clin Invest 2016 May 02;126(5):1885-96 105 Citations |
| 1 | Glutathione S-transferase pi modulates NF-κB activation and pro-inflammatory responses in lung epithelial cells. (Jones JT, Qian X, van der Velden JL, Chia SB, McMillan DH, Flemer S, Hoffman SM, Lahue KG, Schneider RW, Nolin JD, Anathy V, van der Vliet A, Townsend DM, Tew KD, Janssen-Heininger YM) Redox Biol 2016 Aug;8:375-82 69 Citations |
| 1 | An IRF5 Decoy Peptide Reduces Myocardial Inflammation and Fibrosis and Improves Endothelial Cell Function in Tight-Skin Mice. (Weihrauch D, Krolikowski JG, Jones DW, Zaman T, Bamkole O, Struve J, Pillai S, Pagel PS, Lohr NL, Pritchard KA Jr) PLoS One 2016;11(4):e0151999 11 Citations |
| 1 | Neonatal growth restriction-related leptin deficiency enhances leptin-triggered sympathetic activation and central angiotensin II receptor-dependent stress-evoked hypertension. (Peotta V, Rahmouni K, Segar JL, Morgan DA, Pitz KM, Rice OM, Roghair RD) Pediatr Res 2016 Aug;80(2):244-51 5 Citations |
| 1 | HSF1 critically attunes proteotoxic stress sensing by mTORC1 to combat stress and promote growth. (Su KH, Cao J, Tang Z, Dai S, He Y, Sampson SB, Benjamin IJ, Dai C) Nat Cell Biol 2016 May;18(5):527-39 69 Citations |
| 1 | A miR-192-EGR1-HOXB9 regulatory network controls the angiogenic switch in cancer. (Wu SY, Rupaimoole R, Shen F, Pradeep S, Pecot CV, Ivan C, Nagaraja AS, Gharpure KM, Pham E, Hatakeyama H, McGuire MH, Haemmerle M, Vidal-Anaya V, Olsen C, Rodriguez-Aguayo C, Filant J, Ehsanipour EA, Herbrich SM, Maiti SN, Huang L, Kim JH, Zhang X, Han HD, Armaiz-Pena GN, Seviour EG, Tucker S, Zhang M, Yang D, Cooper LJ, Ali-Fehmi R, Bar-Eli M, Lee JS, Ram PT, Baggerly KA, Lopez-Berestein G, Hung MC, Sood AK) Nat Commun 2016 Apr 04;7:11169 114 Citations |
| 1 | LPA/PKD-1-FoxO1 Signaling Axis Mediates Endothelial Cell CD36 Transcriptional Repression and Proangiogenic and Proarteriogenic Reprogramming. (Ren B, Best B, Ramakrishnan DP, Walcott BP, Storz P, Silverstein RL) Arterioscler Thromb Vasc Biol 2016 Jun;36(6):1197-208 43 Citations |
| 4 | The Disease Portals, disease-gene annotation and the RGD disease ontology at the Rat Genome Database. (Hayman GT, Laulederkind SJ, Smith JR, Wang SJ, Petri V, Nigam R, Tutaj M, De Pons J, Dwinell MR, Shimoyama M) Database (Oxford) 2016;2016 19 Citations |
| 2 | Sexual Differentiation of Circadian Clock Function in the Adrenal Gland. (Kloehn I, Pillai SB, Officer L, Klement C, Gasser PJ, Evans JA) Endocrinology 2016 May;157(5):1895-904 19 Citations |
| 2 | Modeling Hematopoiesis and Responses to Radiation Countermeasures in a Bone Marrow-on-a-Chip. (Torisawa YS, Mammoto T, Jiang E, Jiang A, Mammoto A, Watters AL, Bahinski A, Ingber DE) Tissue Eng Part C Methods 2016 May;22(5):509-15 58 Citations |
| 1 | 17β-Estradiol and Agonism of G-protein-Coupled Estrogen Receptor Enhance Hippocampal Memory via Different Cell-Signaling Mechanisms. (Kim J, Szinte JS, Boulware MI, Frick KM) J Neurosci 2016 Mar 16;36(11):3309-21 116 Citations |
| 1 | Blocking Indolamine-2,3-Dioxygenase Rebound Immune Suppression Boosts Antitumor Effects of Radio-Immunotherapy in Murine Models and Spontaneous Canine Malignancies. (Monjazeb AM, Kent MS, Grossenbacher SK, Mall C, Zamora AE, Mirsoian A, Chen M, Kol A, Shiao SL, Reddy A, Perks JR, T N Culp W, Sparger EE, Canter RJ, Sckisel GD, Murphy WJ) Clin Cancer Res 2016 Sep 01;22(17):4328-40 95 Citations |
| 2 | Mechanosensory and ATP Release Deficits following Keratin14-Cre-Mediated TRPA1 Deletion Despite Absence of TRPA1 in Murine Keratinocytes. (Zappia KJ, Garrison SR, Palygin O, Weyer AD, Barabas ME, Lawlor MW, Staruschenko A, Stucky CL) PLoS One 2016;11(3):e0151602 24 Citations |
| 1 | Gut Microbial Metabolite TMAO Enhances Platelet Hyperreactivity and Thrombosis Risk. (Zhu W, Gregory JC, Org E, Buffa JA, Gupta N, Wang Z, Li L, Fu X, Wu Y, Mehrabian M, Sartor RB, McIntyre TM, Silverstein RL, Tang WHW, DiDonato JA, Brown JM, Lusis AJ, Hazen SL) Cell 2016 Mar 24;165(1):111-124 1517 Citations |
| 1 | In Vitro and In Vivo Characterization of the Alkaloid Nuciferine. (Farrell MS, McCorvy JD, Huang XP, Urban DJ, White KL, Giguere PM, Doak AK, Bernstein AI, Stout KA, Park SM, Rodriguiz RM, Gray BW, Hyatt WS, Norwood AP, Webster KA, Gannon BM, Miller GW, Porter JH, Shoichet BK, Fantegrossi WE, Wetsel WC, Roth BL) PLoS One 2016;11(3):e0150602 34 Citations |
| 1 | Reciprocal positive selection for weakness - preventing olaparib resistance by inhibiting BRCA2. (Rytelewski M, Maleki Vareki S, Mangala LS, Romanow L, Jiang D, Pradeep S, Rodriguez-Aguayo C, Lopez-Berestein G, Figueredo R, Ferguson PJ, Vincent M, Sood AK, Koropatnick JD) Oncotarget 2016 Apr 12;7(15):20825-39 8 Citations |
| 1 | Notch Signaling Coordinates Progenitor Cell-Mediated Biliary Regeneration Following Partial Hepatectomy. (Lu J, Zhou Y, Hu T, Zhang H, Shen M, Cheng P, Dai W, Wang F, Chen K, Zhang Y, Wang C, Li J, Zheng Y, Yang J, Zhu R, Wang J, Lu W, Zhang H, Wang J, Xia Y, De Assuncao TM, Jalan-Sakrikar N, Huebert RC, Bin Zhou, Guo C) Sci Rep 2016 Mar 08;6:22754 52 Citations |
| 3 | The adhesion molecule PECAM-1 enhances the TGF-β-mediated inhibition of T cell function. (Newman DK, Fu G, Adams T, Cui W, Arumugam V, Bluemn T, Riese MJ) Sci Signal 2016 Mar 08;9(418):ra27 17 Citations |
| 1 | Metabolic reprogramming of alloantigen-activated T cells after hematopoietic cell transplantation. (Nguyen HD, Chatterjee S, Haarberg KM, Wu Y, Bastian D, Heinrichs J, Fu J, Daenthanasanmak A, Schutt S, Shrestha S, Liu C, Wang H, Chi H, Mehrotra S, Yu XZ) J Clin Invest 2016 Apr 01;126(4):1337-52 93 Citations |
| 1 | Gammaherpesvirus targets peritoneal B-1 B cells for long-term latency. (Rekow MM, Darrah EJ, Mboko WP, Lange PT, Tarakanova VL) Virology 2016 May;492:140-4 28 Citations |
| 1 | Genetic suppression reveals DNA repair-independent antagonism between BRCA1 and COBRA1 in mammary gland development. (Nair SJ, Zhang X, Chiang HC, Jahid MJ, Wang Y, Garza P, April C, Salathia N, Banerjee T, Alenazi FS, Ruan J, Fan JB, Parvin JD, Jin VX, Hu Y, Li R) Nat Commun 2016 Mar 04;7:10913 20 Citations |
| 1 | Loss of Interdependent Binding by the FoxO1 and FoxA1/A2 Forkhead Transcription Factors Culminates in Perturbation of Active Chromatin Marks and Binding of Transcriptional Regulators at Insulin-sensitive Genes. (Yalley A, Schill D, Hatta M, Johnson N, Cirillo LA) J Biol Chem 2016 Apr 15;291(16):8848-61 22 Citations |
| 1 | Estrogen Receptor α Is Required for Maintaining Baseline Renin Expression. (Lu KT, Keen HL, Weatherford ET, Sequeira-Lopez ML, Gomez RA, Sigmund CD) Hypertension 2016 May;67(5):992-9 20 Citations |
| 5 | Alternatively Activated Macrophages Boost Induced Regulatory T and Th17 Cell Responses during Immunotherapy for Colitis. (Haribhai D, Ziegelbauer J, Jia S, Upchurch K, Yan K, Schmitt EG, Salzman NH, Simpson P, Hessner MJ, Chatila TA, Williams CB) J Immunol 2016 Apr 15;196(8):3305-17 40 Citations |
| 1 | Therapeutic evaluation of microRNA-15a and microRNA-16 in ovarian cancer. (Dwivedi SK, Mustafi SB, Mangala LS, Jiang D, Pradeep S, Rodriguez-Aguayo C, Ling H, Ivan C, Mukherjee P, Calin GA, Lopez-Berestein G, Sood AK, Bhattacharya R) Oncotarget 2016 Mar 22;7(12):15093-104 71 Citations |
| 1 | KSHV-encoded vIL-6 collaborates with deregulated c-Myc to drive plasmablastic neoplasms in mice. (Rosean TR, Holman CJ, Tompkins VS, Jing X, Krasowski MD, Rose-John S, Janz S) Blood Cancer J 2016 Feb 26;6(2):e398 18 Citations |
| 1 | PE11, a PE/PPE family protein of Mycobacterium tuberculosis is involved in cell wall remodeling and virulence. (Singh P, Rao RN, Reddy JR, Prasad RB, Kotturu SK, Ghosh S, Mukhopadhyay S) Sci Rep 2016 Feb 23;6:21624 98 Citations |
| 1 | T-bet Promotes Acute Graft-versus-Host Disease by Regulating Recipient Hematopoietic Cells in Mice. (Fu J, Wu Y, Nguyen H, Heinrichs J, Schutt S, Liu Y, Liu C, Jin J, Anasetti C, Yu XZ) J Immunol 2016 Apr 01;196(7):3168-79 6 Citations |
| 1 | PR55α Subunit of Protein Phosphatase 2A Supports the Tumorigenic and Metastatic Potential of Pancreatic Cancer Cells by Sustaining Hyperactive Oncogenic Signaling. (Hein AL, Seshacharyulu P, Rachagani S, Sheinin YM, Ouellette MM, Ponnusamy MP, Mumby MC, Batra SK, Yan Y) Cancer Res 2016 Apr 15;76(8):2243-2253 55 Citations |
| 1 | Purine (N)-Methanocarba Nucleoside Derivatives Lacking an Exocyclic Amine as Selective A3 Adenosine Receptor Agonists. (Tosh DK, Ciancetta A, Warnick E, O'Connor R, Chen Z, Gizewski E, Crane S, Gao ZG, Auchampach JA, Salvemini D, Jacobson KA) J Med Chem 2016 Apr 14;59(7):3249-63 14 Citations |
| 1 | Transcriptome regulation and chromatin occupancy by E2F3 and MYC in mice. (Tang X, Liu H, Srivastava A, Pécot T, Chen Z, Wang Q, Huang K, Sáenz-Robles MT, Cantalupo P, Pipas J, Leone G) Sci Data 2016 Feb 16;3:160008 5 Citations |
| 1 | Interleukin-15-mediated inflammation promotes non-alcoholic fatty liver disease. (Cepero-Donates Y, Lacraz G, Ghobadi F, Rakotoarivelo V, Orkhis S, Mayhue M, Chen YG, Rola-Pleszczynski M, Menendez A, Ilangumaran S, Ramanathan S) Cytokine 2016 Jun;82:102-11 55 Citations |
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| 3 | Risperidone-induced weight gain is mediated through shifts in the gut microbiome and suppression of energy expenditure. (Bahr SM, Weidemann BJ, Castro AN, Walsh JW, deLeon O, Burnett CM, Pearson NA, Murry DJ, Grobe JL, Kirby JR) EBioMedicine 2015 Nov;2(11):1725-34 116 Citations |
| 2 | Estradiol-Mediated Spine Changes in the Dorsal Hippocampus and Medial Prefrontal Cortex of Ovariectomized Female Mice Depend on ERK and mTOR Activation in the Dorsal Hippocampus. (Tuscher JJ, Luine V, Frankfurt M, Frick KM) J Neurosci 2016 Feb 03;36(5):1483-9 120 Citations |
| 1 | Mitoapocynin Treatment Protects Against Neuroinflammation and Dopaminergic Neurodegeneration in a Preclinical Animal Model of Parkinson's Disease. (Ghosh A, Langley MR, Harischandra DS, Neal ML, Jin H, Anantharam V, Joseph J, Brenza T, Narasimhan B, Kanthasamy A, Kalyanaraman B, Kanthasamy AG) J Neuroimmune Pharmacol 2016 Jun;11(2):259-78 88 Citations |
| 1 | Naturally occurring p16(Ink4a)-positive cells shorten healthy lifespan. (Baker DJ, Childs BG, Durik M, Wijers ME, Sieben CJ, Zhong J, Saltness RA, Jeganathan KB, Verzosa GC, Pezeshki A, Khazaie K, Miller JD, van Deursen JM) Nature 2016 Feb 11;530(7589):184-9 2098 Citations |
| 2 | Increasing tetrahydrobiopterin in cardiomyocytes adversely affects cardiac redox state and mitochondrial function independently of changes in NO production. (Sethumadhavan S, Whitsett J, Bennett B, Ionova IA, Pieper GM, Vasquez-Vivar J) Free Radic Biol Med 2016 Apr;93:1-11 8 Citations |
| 3 | Intact Regulatory T-Cell Function but Defective Generation of IL-17A-Producing CD4+ T Cells in XIAP Deficiency. (Gurram B, Hammelev E, Syverson G, Haribhai D, Yan K, Simpson P, Salzman N, Verbsky JW) J Pediatr Gastroenterol Nutr 2016 Aug;63(2):218-25 |
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| 1 | Sustained glucocorticoid exposure recruits cortico-limbic CRH signaling to modulate endocannabinoid function. (Gray JM, Wilson CD, Lee TT, Pittman QJ, Deussing JM, Hillard CJ, McEwen BS, Schulkin J, Karatsoreos IN, Patel S, Hill MN) Psychoneuroendocrinology 2016 Apr;66:151-8 53 Citations |
| 1 | Repeated Activation of Lung Invariant NKT Cells Results in Chronic Obstructive Pulmonary Disease-Like Symptoms. (Tsao CC, Tsao PN, Chen YG, Chuang YH) PLoS One 2016;11(1):e0147710 17 Citations |
| 1 | Proceedings from the Second Haploidentical Stem Cell Transplantation Symposium-Haplo2014, San Francisco, California, December 4, 2014. (Al Malki MM, Horowitz M, Handgretinger R, Leung W, Roy DC, Huang XJ, Fuchs E, Locatelli F, Blaise D, Mineishi S, Martelli M, Miller J, June C, Ai HS, Luznik L, Mavilio D, Lugli E, van den Brink MRM, Champlin RE, Ciurea SO) Biol Blood Marrow Transplant 2016 Apr;22(4):594-604 9 Citations |
| 1 | PTEN recruitment controls synaptic and cognitive function in Alzheimer's models. (Knafo S, Sánchez-Puelles C, Palomer E, Delgado I, Draffin JE, Mingo J, Wahle T, Kaleka K, Mou L, Pereda-Perez I, Klosi E, Faber EB, Chapman HM, Lozano-Montes L, Ortega-Molina A, Ordóñez-Gutiérrez L, Wandosell F, Viña J, Dotti CG, Hall RA, Pulido R, Gerges NZ, Chan AM, Spaller MR, Serrano M, Venero C, Esteban JA) Nat Neurosci 2016 Mar;19(3):443-53 120 Citations |
| 1 | Homeostasis of IL-15 dependent lymphocyte subsets in the liver. (Cepero-Donates Y, Rakotoarivelo V, Mayhue M, Ma A, Chen YG, Ramanathan S) Cytokine 2016 Jun;82:95-101 17 Citations |
| 1 | Identification of β-Amino alcohol grafted 1,4,5 trisubstituted 1,2,3-triazoles as potent antimalarial agents. (Devender N, Gunjan S, Chhabra S, Singh K, Pasam VR, Shukla SK, Sharma A, Jaiswal S, Singh SK, Kumar Y, Lal J, Trivedi AK, Tripathi R, Tripathi RP) Eur J Med Chem 2016 Feb 15;109:187-98 39 Citations |
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| 1 | Artemisinin-derived dimer ART-838 potently inhibited human acute leukemias, persisted in vivo, and synergized with antileukemic drugs. (Fox JM, Moynihan JR, Mott BT, Mazzone JR, Anders NM, Brown PA, Rudek MA, Liu JO, Arav-Boger R, Posner GH, Civin CI, Chen X) Oncotarget 2016 Feb 09;7(6):7268-79 25 Citations |
| 1 | FGFR and PTEN signaling interact during lens development to regulate cell survival. (Chaffee BR, Hoang TV, Leonard MR, Bruney DG, Wagner BD, Dowd JR, Leone G, Ostrowski MC, Robinson ML) Dev Biol 2016 Feb 15;410(2):150-163 24 Citations |
| 1 | Association of O-Antigen Serotype with the Magnitude of Initial Systemic Cytokine Responses and Persistence in the Urinary Tract. (Horvath DJ Jr, Patel AS, Mohamed A, Storm DW, Singh C, Li B, Zhang J, Koff SA, Jayanthi VR, Mason KM, Justice SS) J Bacteriol 2016 Jan 11;198(6):964-72 8 Citations |
| 5 | Nogo-B receptor deficiency causes cerebral vasculature defects during embryonic development in mice. (Rana U, Liu Z, Kumar SN, Zhao B, Hu W, Bordas M, Cossette S, Szabo S, Foeckler J, Weiler H, Chrzanowska-Wodnicka M, Holtz ML, Misra RP, Salato V, North PE, Ramchandran R, Miao QR) Dev Biol 2016 Feb 15;410(2):190-201 19 Citations |
| 3 | Type I Interferon Counteracts Antiviral Effects of Statins in the Context of Gammaherpesvirus Infection. (Lange PT, Darrah EJ, Vonderhaar EP, Mboko WP, Rekow MM, Patel SB, Sidjanin DJ, Tarakanova VL) J Virol 2016 Jan 06;90(7):3342-54 12 Citations |
| 1 | Strategically Timing Inhibition of Phosphatidylinositol 3-Kinase to Maximize Therapeutic Index in Estrogen Receptor Alpha-Positive, PIK3CA-Mutant Breast Cancer. (Yang W, Hosford SR, Dillon LM, Shee K, Liu SC, Bean JR, Salphati L, Pang J, Zhang X, Nannini MA, Demidenko E, Bates D, Lewis LD, Marotti JD, Eastman AR, Miller TW) Clin Cancer Res 2016 May 01;22(9):2250-60 28 Citations |
| 1 | Dietary Vitamin D3 Suppresses Pulmonary Immunopathology Associated with Late-Stage Tuberculosis in C3HeB/FeJ Mice. (Reeme AE, Robinson RT) J Immunol 2016 Feb 01;196(3):1293-304 25 Citations |
| 1 | Hypoxia-upregulated microRNA-630 targets Dicer, leading to increased tumor progression. (Rupaimoole R, Ivan C, Yang D, Gharpure KM, Wu SY, Pecot CV, Previs RA, Nagaraja AS, Armaiz-Pena GN, McGuire M, Pradeep S, Mangala LS, Rodriguez-Aguayo C, Huang L, Bar-Eli M, Zhang W, Lopez-Berestein G, Calin GA, Sood AK) Oncogene 2016 Aug 18;35(33):4312-20 82 Citations |
| 1 | Decitabine enhances chemosensitivity of early T-cell precursor-acute lymphoblastic leukemia cell lines and patient-derived samples. (Lu BY, Thanawala SU, Zochowski KC, Burke MJ, Carroll WL, Bhatla T) Leuk Lymphoma 2016 Aug;57(8):1938-41 25 Citations |
| 2 | Small GTPase Rap1 Is Essential for Mouse Development and Formation of Functional Vasculature. (Chrzanowska-Wodnicka M, White GC 2nd, Quilliam LA, Whitehead KJ) PLoS One 2015;10(12):e0145689 37 Citations |
| 1 | R-Ras Regulates Murine T Cell Migration and Intercellular Adhesion Molecule-1 Binding. (Yan X, Yan M, Guo Y, Singh G, Chen Y, Yu M, Wang D, Hillery CA, Chan AM) PLoS One 2015;10(12):e0145218 8 Citations |
| 1 | The Macrophage Inhibitor CNI-1493 Blocks Metastasis in a Mouse Model of Ewing Sarcoma through Inhibition of Extravasation. (Hesketh AJ, Maloney C, Behr CA, Edelman MC, Glick RD, Al-Abed Y, Symons M, Soffer SZ, Steinberg BM) PLoS One 2015;10(12):e0145197 15 Citations |
| 1 | Further Advances in Optimizing (2-Phenylcyclopropyl)methylamines as Novel Serotonin 2C Agonists: Effects on Hyperlocomotion, Prepulse Inhibition, and Cognition Models. (Cheng J, Giguere PM, Schmerberg CM, Pogorelov VM, Rodriguiz RM, Huang XP, Zhu H, McCorvy JD, Wetsel WC, Roth BL, Kozikowski AP) J Med Chem 2016 Jan 28;59(2):578-91 23 Citations |
| 2 | Structural basis for PECAM-1 homophilic binding. (Paddock C, Zhou D, Lertkiatmongkol P, Newman PJ, Zhu J) Blood 2016 Feb 25;127(8):1052-61 47 Citations |
| 1 | The Dose-Response Relationship of bacillus Calmette-Guérin and Urothelial Carcinoma Cell Biology. (Shah G, Zhang G, Chen F, Cao Y, Kalyanaraman B, See WA) J Urol 2016 Jun;195(6):1903-10 13 Citations |
| 1 | Endothelial Cell Surface Expressed Chemotaxis and Apoptosis Regulator (ECSCR) Regulates Lipolysis in White Adipocytes via the PTEN/AKT Signaling Pathway. (Kilari S, Cossette S, Pooya S, Bordas M, Huang YW, Ramchandran R, Wilkinson GA) PLoS One 2015;10(12):e0144185 8 Citations |
| 2 | Genetic and pharmacological manipulation of glyoxalase 1 regulates voluntary ethanol consumption in mice. (McMurray KM, Sidhu PS, Cook JM, Arnold LA, Palmer AA) Addict Biol 2017 Mar;22(2):381-389 9 Citations |
| 1 | Long Noncoding RNA Ceruloplasmin Promotes Cancer Growth by Altering Glycolysis. (Rupaimoole R, Lee J, Haemmerle M, Ling H, Previs RA, Pradeep S, Wu SY, Ivan C, Ferracin M, Dennison JB, Millward NMZ, Nagaraja AS, Gharpure KM, McGuire M, Sam N, Armaiz-Pena GN, Sadaoui NC, Rodriguez-Aguayo C, Calin GA, Drapkin RI, Kovacs J, Mills GB, Zhang W, Lopez-Berestein G, Bhattacharya PK, Sood AK) Cell Rep 2015 Dec 22;13(11):2395-2402 100 Citations |
| 1 | Intravital Imaging of Vascular Transmigration by the Lyme Spirochete: Requirement for the Integrin Binding Residues of the B. burgdorferi P66 Protein. (Kumar D, Ristow LC, Shi M, Mukherjee P, Caine JA, Lee WY, Kubes P, Coburn J, Chaconas G) PLoS Pathog 2015 Dec;11(12):e1005333 46 Citations |
| 1 | Role of IL-10 in Resolution of Inflammation and Functional Recovery after Peripheral Nerve Injury. (Siqueira Mietto B, Kroner A, Girolami EI, Santos-Nogueira E, Zhang J, David S) J Neurosci 2015 Dec 16;35(50):16431-42 115 Citations |
| 2 | Vascular hepoxilin and trioxilins mediate vasorelaxation through TP receptor inhibition in mouse arteries. (Siangjong L, Goldman DH, Kriska T, Gauthier KM, Smyth EM, Puli N, Kumar G, Falck JR, Campbell WB) Acta Physiol (Oxf) 2017 Jan;219(1):188-201 18 Citations |
| 1 | The immunogenicity of platelet-derived FVIII in hemophilia A mice with or without preexisting anti-FVIII immunity. (Chen Y, Schroeder JA, Chen J, Luo X, Baumgartner CK, Montgomery RR, Hu J, Shi Q) Blood 2016 Mar 10;127(10):1346-54 23 Citations |
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| 1 | Smooth Muscle Peroxisome Proliferator-Activated Receptor γ Plays a Critical Role in Formation and Rupture of Cerebral Aneurysms in Mice In Vivo. (Hasan DM, Starke RM, Gu H, Wilson K, Chu Y, Chalouhi N, Heistad DD, Faraci FM, Sigmund CD) Hypertension 2015 Jul;66(1):211-20 33 Citations |
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| 1 | cCMP and cUMP occur in vivo. (Bähre H, Hartwig C, Munder A, Wolter S, Stelzer T, Schirmer B, Beckert U, Frank DW, Tümmler B, Kaever V, Seifert R) Biochem Biophys Res Commun 2015 May 15;460(4):909-14 33 Citations |
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| 1 | Alcohol inhibits osteopontin-dependent transforming growth factor-β1 expression in human mesenchymal stem cells. (Driver J, Weber CE, Callaci JJ, Kothari AN, Zapf MA, Roper PM, Borys D, Franzen CA, Gupta GN, Wai PY, Zhang J, Denning MF, Kuo PC, Mi Z) J Biol Chem 2015 Apr 17;290(16):9959-73 27 Citations |
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| 1 | Macrophage apoAI protects against dyslipidemia-induced dermatitis and atherosclerosis without affecting HDL. (Tavori H, Su YR, Yancey PG, Giunzioni I, Wilhelm AJ, Blakemore JL, Zabalawi M, Linton MF, Sorci-Thomas MG, Fazio S) J Lipid Res 2015 Mar;56(3):635-643 27 Citations |
| 1 | Bruton tyrosine kinase is a therapeutic target in stem-like cells from multiple myeloma. (Yang Y, Shi J, Gu Z, Salama ME, Das S, Wendlandt E, Xu H, Huang J, Tao Y, Hao M, Franqui R, Levasseur D, Janz S, Tricot G, Zhan F) Cancer Res 2015 Feb 01;75(3):594-604 72 Citations |
| 1 | Dynamic switching of active promoter and enhancer domains regulates Tet1 and Tet2 expression during cell state transitions between pluripotency and differentiation. (Sohni A, Bartoccetti M, Khoueiry R, Spans L, Vande Velde J, De Troyer L, Pulakanti K, Claessens F, Rao S, Koh KP) Mol Cell Biol 2015 Mar;35(6):1026-42 41 Citations |
| 1 | Photo activation of HPPH encapsulated in "Pocket" liposomes triggers multiple drug release and tumor cell killing in mouse breast cancer xenografts. (Sine J, Urban C, Thayer D, Charron H, Valim N, Tata DB, Schiff R, Blumenthal R, Joshi A, Puri A) Int J Nanomedicine 2015;10:125-45 32 Citations |
| 2 | Structure-function analysis of CCL28 in the development of post-viral asthma. (Thomas MA, Buelow BJ, Nevins AM, Jones SE, Peterson FC, Gundry RL, Grayson MH, Volkman BF) J Biol Chem 2015 Feb 13;290(7):4528-36 19 Citations |
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| 1 | Fabry disease: renal sphingolipid distribution in the α-Gal A knockout mouse model by mass spectrometric and immunohistochemical imaging. (Kuchar L, Faltyskova H, Krasny L, Dobrovolny R, Hulkova H, Ledvinova J, Volny M, Strohalm M, Lemr K, Kryspinova L, Asfaw B, Rybová J, Desnick RJ, Havlicek V) Anal Bioanal Chem 2015 Mar;407(8):2283-91 18 Citations |
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| 1 | A systematic analysis of neonatal mouse heart regeneration after apical resection. (Bryant DM, O'Meara CC, Ho NN, Gannon J, Cai L, Lee RT) J Mol Cell Cardiol 2015 Feb;79:315-8 89 Citations |
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| 1 | Osteopontin mediates an MZF1-TGF-β1-dependent transformation of mesenchymal stem cells into cancer-associated fibroblasts in breast cancer. (Weber CE, Kothari AN, Wai PY, Li NY, Driver J, Zapf MA, Franzen CA, Gupta GN, Osipo C, Zlobin A, Syn WK, Zhang J, Kuo PC, Mi Z) Oncogene 2015 Sep 10;34(37):4821-33 175 Citations |
| 1 | Transcriptional profiling at whole population and single cell levels reveals somatosensory neuron molecular diversity. (Chiu IM, Barrett LB, Williams EK, Strochlic DE, Lee S, Weyer AD, Lou S, Bryman GS, Roberson DP, Ghasemlou N, Piccoli C, Ahat E, Wang V, Cobos EJ, Stucky CL, Ma Q, Liberles SD, Woolf CJ) Elife 2014 Dec 19;3 188 Citations |
| 1 | Genetic, epigenetic, and mechanistic studies of temporomandibular disorders and overlapping pain conditions. (Munzenmaier DH, Wilentz J, Cowley AW Jr) Mol Pain 2014 Dec 15;10:72 10 Citations |
| 1 | EGF is required for cardiac differentiation of P19CL6 cells through interaction with GATA-4 in a time- and dose-dependent manner. (Ma CX, Song YL, Xiao L, Xue LX, Li WJ, Laforest B, Komati H, Wang WP, Jia ZQ, Zhou CY, Zou Y, Nemer M, Zhang SF, Bai X, Wu H, Zang MX) Cell Mol Life Sci 2015 May;72(10):2005-22 10 Citations |
| 1 | Prenatal stress induces spatial memory deficits and epigenetic changes in the hippocampus indicative of heterochromatin formation and reduced gene expression. (Benoit JD, Rakic P, Frick KM) Behav Brain Res 2015 Mar 15;281:1-8 84 Citations |
| 1 | Thrombospondin-1 restrains neutrophil granule serine protease function and regulates the innate immune response during Klebsiella pneumoniae infection. (Zhao Y, Olonisakin TF, Xiong Z, Hulver M, Sayeed S, Yu MT, Gregory AD, Kochman EJ, Chen BB, Mallampalli RK, Sun M, Silverstein RL, Stolz DB, Shapiro SD, Ray A, Ray P, Lee JS) Mucosal Immunol 2015 Jul;8(4):896-905 47 Citations |
| 1 | The PI3K/mTOR dual inhibitor P7170 demonstrates potent activity against endocrine-sensitive and endocrine-resistant ER+ breast cancer. (Bean JR, Hosford SR, Symonds LK, Owens P, Dillon LM, Yang W, Shee K, Schwartz GN, Marotti JD, Muller KE, Rosenkranz KM, Barth RJ, Chen VS, Agarwal VR, Miller TW) Breast Cancer Res Treat 2015 Jan;149(1):69-79 14 Citations |
| 2 | Copy number gain of hsa-miR-569 at 3q26.2 leads to loss of TP53INP1 and aggressiveness of epithelial cancers. (Chaluvally-Raghavan P, Zhang F, Pradeep S, Hamilton MP, Zhao X, Rupaimoole R, Moss T, Lu Y, Yu S, Pecot CV, Aure MR, Peuget S, Rodriguez-Aguayo C, Han HD, Zhang D, Venkatanarayan A, Krohn M, Kristensen VN, Gagea M, Ram P, Liu W, Lopez-Berestein G, Lorenzi PL, Børresen-Dale AL, Chin K, Gray J, Dusetti NJ, McGuire SE, Flores ER, Sood AK, Mills GB) Cancer Cell 2014 Dec 08;26(6):863-879 48 Citations |
| 1 | Glycosaminoglycan binding by Borrelia burgdorferi adhesin BBK32 specifically and uniquely promotes joint colonization. (Lin YP, Chen Q, Ritchie JA, Dufour NP, Fischer JR, Coburn J, Leong JM) Cell Microbiol 2015 Jun;17(6):860-75 58 Citations |
| 1 | Dietary supplementation with docosahexanoic acid (DHA) increases red blood cell membrane flexibility in mice with sickle cell disease. (Wandersee NJ, Maciaszek JL, Giger KM, Hanson MS, Zheng S, Guo Y, Mickelson B, Hillery CA, Lykotrafitis G, Low PS, Hogg N) Blood Cells Mol Dis 2015 Feb;54(2):183-8 26 Citations |
| 2 | The Ashwell-Morell receptor regulates hepatic thrombopoietin production via JAK2-STAT3 signaling. (Grozovsky R, Begonja AJ, Liu K, Visner G, Hartwig JH, Falet H, Hoffmeister KM) Nat Med 2015 Jan;21(1):47-54 277 Citations |
| 1 | Transcriptional reversion of cardiac myocyte fate during mammalian cardiac regeneration. (O'Meara CC, Wamstad JA, Gladstone RA, Fomovsky GM, Butty VL, Shrikumar A, Gannon JB, Boyer LA, Lee RT) Circ Res 2015 Feb 27;116(5):804-15 130 Citations |
| 1 | Structure, dynamics and implied gating mechanism of a human cyclic nucleotide-gated channel. (Gofman Y, Schärfe C, Marks DS, Haliloglu T, Ben-Tal N) PLoS Comput Biol 2014 Dec;10(12):e1003976 9 Citations |
| 1 | Krüppel-like factor KLF10 regulates transforming growth factor receptor II expression and TGF-β signaling in CD8+ T lymphocytes. (Papadakis KA, Krempski J, Reiter J, Svingen P, Xiong Y, Sarmento OF, Huseby A, Johnson AJ, Lomberk GA, Urrutia RA, Faubion WA) Am J Physiol Cell Physiol 2015 Mar 01;308(5):C362-71 24 Citations |
| 2 | Dynamin 2-dependent endocytosis is required for normal megakaryocyte development in mice. (Bender M, Giannini S, Grozovsky R, Jönsson T, Christensen H, Pluthero FG, Ko A, Mullally A, Kahr WH, Hoffmeister KM, Falet H) Blood 2015 Feb 05;125(6):1014-24 45 Citations |
| 1 | Integrated genomic analyses in bronchopulmonary dysplasia. (Ambalavanan N, Cotten CM, Page GP, Carlo WA, Murray JC, Bhattacharya S, Mariani TJ, Cuna AC, Faye-Petersen OM, Kelly D, Higgins RD, Genomics and Cytokine Subcommittees of the Eunice Kennedy Shriver National Institute of Child Health and Human Development Neonatal Research Network) J Pediatr 2015 Mar;166(3):531-7.e13 96 Citations |
| 1 | Preventive azithromycin treatment reduces noninfectious lung injury and acute graft-versus-host disease in a murine model of allogeneic hematopoietic cell transplantation. (Radhakrishnan SV, Palaniyandi S, Mueller G, Miklos S, Hager M, Spacenko E, Karlsson FJ, Huber E, Kittan NA, Hildebrandt GC) Biol Blood Marrow Transplant 2015 Jan;21(1):30-8 16 Citations |
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| 1 | Cdk1, PKCδ and calcineurin-mediated Drp1 pathway contributes to mitochondrial fission-induced cardiomyocyte death. (Zaja I, Bai X, Liu Y, Kikuchi C, Dosenovic S, Yan Y, Canfield SG, Bosnjak ZJ) Biochem Biophys Res Commun 2014 Oct 31;453(4):710-21 112 Citations |
| 1 | Expression quantitative trait loci and receptor pharmacology implicate Arg1 and the GABA-A receptor as therapeutic targets in neuroblastoma. (Hackett CS, Quigley DA, Wong RA, Chen J, Cheng C, Song YK, Wei JS, Pawlikowska L, Bao Y, Goldenberg DD, Nguyen K, Gustafson WC, Rallapalli SK, Cho YJ, Cook JM, Kozlov S, Mao JH, Van Dyke T, Kwok PY, Khan J, Balmain A, Fan Q, Weiss WA) Cell Rep 2014 Nov 06;9(3):1034-46 27 Citations |
| 1 | The earliest metanephric arteriolar progenitors and their role in kidney vascular development. (Sequeira-Lopez ML, Lin EE, Li M, Hu Y, Sigmund CD, Gomez RA) Am J Physiol Regul Integr Comp Physiol 2015 Jan 15;308(2):R138-49 91 Citations |
| 1 | In vivo phenotypic screening for treating chronic neuropathic pain: modification of C2-arylethynyl group of conformationally constrained A3 adenosine receptor agonists. (Tosh DK, Finley A, Paoletta S, Moss SM, Gao ZG, Gizewski ET, Auchampach JA, Salvemini D, Jacobson KA) J Med Chem 2014 Dec 11;57(23):9901-14 51 Citations |
| 1 | Endothelial TWIST1 promotes pathological ocular angiogenesis. (Li J, Liu CH, Sun Y, Gong Y, Fu Z, Evans LP, Tian KT, Juan AM, Hurst CG, Mammoto A, Chen J) Invest Ophthalmol Vis Sci 2014 Nov 20;55(12):8267-77 40 Citations |
| 1 | Virology, immunology and pathology of human rabies during treatment. (Caicedo Y, Paez A, Kuzmin I, Niezgoda M, Orciari LA, Yager PA, Recuenco S, Franka R, Velasco-Villa A, Willoughby RE Jr) Pediatr Infect Dis J 2015 May;34(5):520-8 19 Citations |
| 1 | T-bet is critical for the development of acute graft-versus-host disease through controlling T cell differentiation and function. (Fu J, Wang D, Yu Y, Heinrichs J, Wu Y, Schutt S, Kaosaard K, Liu C, Haarberg K, Bastian D, McDonald DG, Anasetti C, Yu XZ) J Immunol 2015 Jan 01;194(1):388-97 34 Citations |
| 1 | Nonenzymatic conversion of ADP-ribosylated arginines to ornithine alters the biological activities of human neutrophil peptide-1. (Stevens LA, Barbieri JT, Piszczek G, Otuonye AN, Levine RL, Zheng G, Moss J) J Immunol 2014 Dec 15;193(12):6144-51 5 Citations |
| 1 | NIAM-deficient mice are predisposed to the development of proliferative lesions including B-cell lymphomas. (Reed SM, Hagen J, Muniz VP, Rosean TR, Borcherding N, Sciegienka S, Goeken JA, Naumann PW, Zhang W, Tompkins VS, Janz S, Meyerholz DK, Quelle DE) PLoS One 2014;9(11):e112126 8 Citations |
| 1 | Genetic interference with peroxisome proliferator-activated receptor γ in smooth muscle enhances myogenic tone in the cerebrovasculature via A Rho kinase-dependent mechanism. (De Silva TM, Ketsawatsomkron P, Pelham C, Sigmund CD, Faraci FM) Hypertension 2015 Feb;65(2):345-51 20 Citations |
| 1 | Borrelia burgdorferi arthritis-associated locus Bbaa1 regulates Lyme arthritis and K/B×N serum transfer arthritis through intrinsic control of type I IFN production. (Ma Y, Bramwell KK, Lochhead RB, Paquette JK, Zachary JF, Weis JH, Teuscher C, Weis JJ) J Immunol 2014 Dec 15;193(12):6050-60 19 Citations |
| 1 | Attenuation of cystitis and pain sensation in mice lacking fatty acid amide hydrolase. (Wang ZY, Wang P, Hillard CJ, Bjorling DE) J Mol Neurosci 2015 Apr;55(4):968-76 14 Citations |
| 1 | TRPV4 mediates myofibroblast differentiation and pulmonary fibrosis in mice. (Rahaman SO, Grove LM, Paruchuri S, Southern BD, Abraham S, Niese KA, Scheraga RG, Ghosh S, Thodeti CK, Zhang DX, Moran MM, Schilling WP, Tschumperlin DJ, Olman MA) J Clin Invest 2014 Dec;124(12):5225-38 230 Citations |
| 1 | Isoliquiritigenin induces apoptosis and inhibits xenograft tumor growth of human lung cancer cells by targeting both wild type and L858R/T790M mutant EGFR. (Jung SK, Lee MH, Lim DY, Kim JE, Singh P, Lee SY, Jeong CH, Lim TG, Chen H, Chi YI, Kundu JK, Lee NH, Lee CC, Cho YY, Bode AM, Lee KW, Dong Z) J Biol Chem 2014 Dec 26;289(52):35839-48 106 Citations |
| 2 | Reproducible and quantitative model of infection of Dermacentor variabilis with the live vaccine strain of Francisella tularensis. (Coburn J, Maier T, Casey M, Padmore L, Sato H, Frank DW) Appl Environ Microbiol 2015 Jan;81(1):386-95 8 Citations |
| 2 | Expression of insulin-like growth factor 2 receptor in corneal keratocytes during differentiation and in response to wound healing. (Bohnsack RN, Warejcka DJ, Wang L, Gillespie SR, Bernstein AM, Twining SS, Dahms NM) Invest Ophthalmol Vis Sci 2014 Oct 30;55(12):7697-708 19 Citations |
| 3 | Sickle cell disease increases high mobility group box 1: a novel mechanism of inflammation. (Xu H, Wandersee NJ, Guo Y, Jones DW, Holzhauer SL, Hanson MS, Machogu E, Brousseau DC, Hogg N, Densmore JC, Kaul S, Hillery CA, Pritchard KA Jr) Blood 2014 Dec 18;124(26):3978-81 45 Citations |
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| 2 | Binding and cytotoxic trafficking of cholesterol hydroperoxides by sterol carrier protein-2. (Girotti AW, Kriska T) Methods Mol Biol 2015;1208:421-35 2 Citations |
| 1 | Deletion of interleukin-6 prevents cardiac inflammation, fibrosis and dysfunction without affecting blood pressure in angiotensin II-high salt-induced hypertension. (González GE, Rhaleb NE, D'Ambrosio MA, Nakagawa P, Liu Y, Leung P, Dai X, Yang XP, Peterson EL, Carretero OA) J Hypertens 2015 Jan;33(1):144-52 89 Citations |
| 1 | A mitochondrial-targeted coenzyme q analog prevents weight gain and ameliorates hepatic dysfunction in high-fat-fed mice. (Fink BD, Herlein JA, Guo DF, Kulkarni C, Weidemann BJ, Yu L, Grobe JL, Rahmouni K, Kerns RJ, Sivitz WI) J Pharmacol Exp Ther 2014 Dec;351(3):699-708 38 Citations |
| 1 | Direct pro-inflammatory effects of prorenin on microglia. (Shi P, Grobe JL, Desland FA, Zhou G, Shen XZ, Shan Z, Liu M, Raizada MK, Sumners C) PLoS One 2014;9(10):e92937 70 Citations |
| 2 | Upholding the T cell immune-regulatory function of CD31 inhibits the formation of T/B immunological synapses in vitro and attenuates the development of experimental autoimmune arthritis in vivo. (Clement M, Fornasa G, Loyau S, Morvan M, Andreata F, Guedj K, Khallou-Laschet J, Larghi P, Le Roux D, Bismuth G, Chiocchia G, Hivroz C, Newman DK, Nicoletti A, Caligiuri G) J Autoimmun 2015 Jan;56:23-33 18 Citations |
| 1 | Identification of cell-binding adhesins of Leptospira interrogans. (Evangelista KV, Hahn B, Wunder EA Jr, Ko AI, Haake DA, Coburn J) PLoS Negl Trop Dis 2014 Oct;8(10):e3215 32 Citations |
| 1 | Chemical structure and morphology of dorsal root ganglion neurons from naive and inflamed mice. (Barabas ME, Mattson EC, Aboualizadeh E, Hirschmugl CJ, Stucky CL) J Biol Chem 2014 Dec 05;289(49):34241-9 21 Citations |
| 1 | Actin dynamics is rapidly regulated by the PTEN and PIP2 signaling pathways leading to myocyte hypertrophy. (Li J, Tanhehco EJ, Russell B) Am J Physiol Heart Circ Physiol 2014 Dec 01;307(11):H1618-25 28 Citations |
| 1 | The tumor microenvironment is the main source of IL-6 for plasma cell tumor development in mice. (Rosean TR, Tompkins VS, Olivier AK, Sompallae R, Norian LA, Morse HC 3rd, Waldschmidt TJ, Janz S) Leukemia 2015 Jan;29(1):233-7 17 Citations |
| 1 | A translatable predictor of human radiation exposure. (Lucas J, Dressman HK, Suchindran S, Nakamura M, Chao NJ, Himburg H, Minor K, Phillips G, Ross J, Abedi M, Terbrueggen R, Chute JP) PLoS One 2014;9(9):e107897 45 Citations |
| 1 | Pleiotrophin mediates hematopoietic regeneration via activation of RAS. (Himburg HA, Yan X, Doan PL, Quarmyne M, Micewicz E, McBride W, Chao NJ, Slamon DJ, Chute JP) J Clin Invest 2014 Nov;124(11):4753-8 46 Citations |
| 1 | NF-κB is crucial in proximal T-cell signaling for calcium influx and NFAT activation. (Bronk CC, Yoder S, Hopewell EL, Yang S, Celis E, Yu XZ, Beg AA) Eur J Immunol 2014 Dec;44(12):3741-6 10 Citations |
| 1 | MACE: model based analysis of ChIP-exo. (Wang L, Chen J, Wang C, Uusküla-Reimand L, Chen K, Medina-Rivera A, Young EJ, Zimmermann MT, Yan H, Sun Z, Zhang Y, Wu ST, Huang H, Wilson MD, Kocher JP, Li W) Nucleic Acids Res 2014 Nov 10;42(20):e156 66 Citations |
| 1 | Honokiol inhibits lung tumorigenesis through inhibition of mitochondrial function. (Pan J, Zhang Q, Liu Q, Komas SM, Kalyanaraman B, Lubet RA, Wang Y, You M) Cancer Prev Res (Phila) 2014 Nov;7(11):1149-59 36 Citations |
| 2 | Sall4 overexpression blocks murine hematopoiesis in a dose-dependent manner. (Milanovich S, Peterson J, Allred J, Stelloh C, Rajasekaran K, Fisher J, Duncan SA, Malarkannan S, Rao S) Exp Hematol 2015 Jan;43(1):53-64.e1-8 17 Citations |
| 3 | Identification of a novel gene for diabetic traits in rats, mice, and humans. (Tsaih SW, Holl K, Jia S, Kaldunski M, Tschannen M, He H, Andrae JW, Li SH, Stoddard A, Wiederhold A, Parrington J, Ruas da Silva M, Galione A, Meigs J, Meta-Analyses of Glucose and Insulin-Related Traits Consortium (MAGIC) Investigators, Hoffmann RG, Simpson P, Jacob H, Hessner M, Solberg Woods LC) Genetics 2014 Sep;198(1):17-29 39 Citations |
| 1 | Cyclooxygenase-2, prostaglandin E2, and prostanoid receptor EP2 in fluid flow shear stress-mediated injury in the solitary kidney. (Srivastava T, Alon US, Cudmore PA, Tarakji B, Kats A, Garola RE, Duncan RS, McCarthy ET, Sharma R, Johnson ML, Bonewald LF, El-Meanawy A, Savin VJ, Sharma M) Am J Physiol Renal Physiol 2014 Dec 15;307(12):F1323-33 27 Citations |
| 1 | CSF1-ETS2-induced microRNA in myeloid cells promote metastatic tumor growth. (Mathsyaraja H, Thies K, Taffany DA, Deighan C, Liu T, Yu L, Fernandez SA, Shapiro C, Otero J, Timmers C, Lustberg MB, Chalmers J, Leone G, Ostrowski MC) Oncogene 2015 Jul;34(28):3651-61 57 Citations |
| 1 | NEK2 mediates ALDH1A1-dependent drug resistance in multiple myeloma. (Yang Y, Zhou W, Xia J, Gu Z, Wendlandt E, Zhan X, Janz S, Tricot G, Zhan F) Oncotarget 2014 Dec 15;5(23):11986-97 60 Citations |
| 1 | Isolation and physiological analysis of mouse cardiomyocytes. (Roth GM, Bader DM, Pfaltzgraff ER) J Vis Exp 2014 Sep 07(91):e51109 18 Citations |
| 1 | Krüppel-like factor 9 promotes hepatic cytochrome P450 2D6 expression during pregnancy in CYP2D6-humanized mice. (Koh KH, Pan X, Zhang W, McLachlan A, Urrutia R, Jeong H) Mol Pharmacol 2014 Dec;86(6):727-35 33 Citations |
| 2 | Improved rat genome gene prediction by integration of ESTs with RNA-Seq information. (Li L, Chen E, Yang C, Zhu J, Jayaraman P, De Pons J, Kaczorowski CC, Jacob HJ, Greene AS, Hodges MR, Cowley AW Jr, Liang M, Xu H, Liu P, Lu Y) Bioinformatics 2015 Jan 01;31(1):25-32 5 Citations |
| 1 | Assessment and optimization of electroporation-assisted tumoral nanoparticle uptake in a nude mouse model of pancreatic ductal adenocarcinoma. (West DL, White SB, Zhang Z, Larson AC, Omary RA) Int J Nanomedicine 2014;9:4169-76 17 Citations |
| 1 | Involvement of GABA transporters in atropine-treated myopic retina as revealed by iTRAQ quantitative proteomics. (Barathi VA, Chaurasia SS, Poidinger M, Koh SK, Tian D, Ho C, Iuvone PM, Beuerman RW, Zhou L) J Proteome Res 2014 Nov 07;13(11):4647-58 67 Citations |
| 1 | SR-BI/CD36 chimeric receptors define extracellular subdomains of SR-BI critical for cholesterol transport. (Kartz GA, Holme RL, Nicholson K, Sahoo D) Biochemistry 2014 Oct 07;53(39):6173-82 28 Citations |
| 1 | Reducing CD73 expression by IL1β-Programmed Th17 cells improves immunotherapeutic control of tumors. (Chatterjee S, Thyagarajan K, Kesarwani P, Song JH, Soloshchenko M, Fu J, Bailey SR, Vasu C, Kraft AS, Paulos CM, Yu XZ, Mehrotra S) Cancer Res 2014 Nov 01;74(21):6048-59 50 Citations |
| 1 | Oral-resident natural Th17 cells and γδ T cells control opportunistic Candida albicans infections. (Conti HR, Peterson AC, Brane L, Huppler AR, Hernández-Santos N, Whibley N, Garg AV, Simpson-Abelson MR, Gibson GA, Mamo AJ, Osborne LC, Bishu S, Ghilardi N, Siebenlist U, Watkins SC, Artis D, McGeachy MJ, Gaffen SL) J Exp Med 2014 Sep 22;211(10):2075-84 222 Citations |
| 1 | Ubiquitin-conjugating enzyme Ubc13 controls breast cancer metastasis through a TAK1-p38 MAP kinase cascade. (Wu X, Zhang W, Font-Burgada J, Palmer T, Hamil AS, Biswas SK, Poidinger M, Borcherding N, Xie Q, Ellies LG, Lytle NK, Wu LW, Fox RG, Yang J, Dowdy SF, Reya T, Karin M) Proc Natl Acad Sci U S A 2014 Sep 23;111(38):13870-5 90 Citations |
| 1 | Megakaryocyte-specific Profilin1-deficiency alters microtubule stability and causes a Wiskott-Aldrich syndrome-like platelet defect. (Bender M, Stritt S, Nurden P, van Eeuwijk JM, Zieger B, Kentouche K, Schulze H, Morbach H, Stegner D, Heinze KG, Dütting S, Gupta S, Witke W, Falet H, Fischer A, Hartwig JH, Nieswandt B) Nat Commun 2014 Sep 04;5:4746 88 Citations |
| 1 | Hyper-inflammation and skin destruction mediated by rosiglitazone activation of macrophages in IL-6 deficiency. (Das LM, Rosenjack J, Au L, Galle PS, Hansen MB, Cathcart MK, McCormick TS, Cooper KD, Silverstein RL, Lu KQ) J Invest Dermatol 2015 Feb;135(2):389-399 13 Citations |
| 1 | Role of peroxisome proliferator-activated receptor-γ in vascular muscle in the cerebral circulation. (De Silva TM, Modrick ML, Ketsawatsomkron P, Lynch C, Chu Y, Pelham CJ, Sigmund CD, Faraci FM) Hypertension 2014 Nov;64(5):1088-93 25 Citations |
| 1 | Isolation of murine valve endothelial cells. (Miller LJ, Lincoln J) J Vis Exp 2014 Aug 21(90) 4 Citations |
| 1 | Murine splenic CD4⁺ T cells, induced by innate immune cell interactions and secreted factors, develop antileukemia cytotoxicity. (Nelles ME, Moreau JM, Furlonger CL, Berger A, Medin JA, Paige CJ) Cancer Immunol Res 2014 Nov;2(11):1113-24 11 Citations |
| 1 | Copackaging of multiple adeno-associated viral vectors in a single production step. (Doerfler PA, Byrne BJ, Clément N) Hum Gene Ther Methods 2014 Oct;25(5):269-76 3 Citations |
| 2 | Regulation of object recognition and object placement by ovarian sex steroid hormones. (Tuscher JJ, Fortress AM, Kim J, Frick KM) Behav Brain Res 2015 May 15;285:140-57 101 Citations |
| 1 | TNF and increased intracellular iron alter macrophage polarization to a detrimental M1 phenotype in the injured spinal cord. (Kroner A, Greenhalgh AD, Zarruk JG, Passos Dos Santos R, Gaestel M, David S) Neuron 2014 Sep 03;83(5):1098-116 523 Citations |
| 1 | Blockade of 2-arachidonoylglycerol hydrolysis produces antidepressant-like effects and enhances adult hippocampal neurogenesis and synaptic plasticity. (Zhang Z, Wang W, Zhong P, Liu SJ, Long JZ, Zhao L, Gao HQ, Cravatt BF, Liu QS) Hippocampus 2015 Jan;25(1):16-26 80 Citations |
| 1 | 17β-Estradiol regulates histone alterations associated with memory consolidation and increases Bdnf promoter acetylation in middle-aged female mice. (Fortress AM, Kim J, Poole RL, Gould TJ, Frick KM) Learn Mem 2014 Sep;21(9):457-67 69 Citations |
| 1 | Molecular architecture of mammalian nitric oxide synthases. (Campbell MG, Smith BC, Potter CS, Carragher B, Marletta MA) Proc Natl Acad Sci U S A 2014 Sep 02;111(35):E3614-23 91 Citations |
| 2 | Role of vascular smooth muscle PPARγ in regulating AT1 receptor signaling and angiotensin II-dependent hypertension. (Carrillo-Sepulveda MA, Keen HL, Davis DR, Grobe JL, Sigmund CD) PLoS One 2014;9(8):e103786 11 Citations |
| 1 | Bystander activation and anti-tumor effects of CD8+ T cells following Interleukin-2 based immunotherapy is independent of CD4+ T cell help. (Monjazeb AM, Tietze JK, Grossenbacher SK, Hsiao HH, Zamora AE, Mirsoian A, Koehn B, Blazar BR, Weiss JM, Wiltrout RH, Sckisel GD, Murphy WJ) PLoS One 2014;9(8):e102709 29 Citations |
| 1 | PERK-dependent activation of JAK1 and STAT3 contributes to endoplasmic reticulum stress-induced inflammation. (Meares GP, Liu Y, Rajbhandari R, Qin H, Nozell SE, Mobley JA, Corbett JA, Benveniste EN) Mol Cell Biol 2014 Oct;34(20):3911-25 183 Citations |
| 1 | Dissecting the complement pathway in hepatic injury and regeneration with a novel protective strategy. (Marshall KM, He S, Zhong Z, Atkinson C, Tomlinson S) J Exp Med 2014 Aug 25;211(9):1793-805 63 Citations |
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| 2 | Genetic inactivation of the pancreatitis-inducible gene Nupr1 impairs PanIN formation by modulating Kras(G12D)-induced senescence. (Grasso D, Garcia MN, Hamidi T, Cano C, Calvo E, Lomberk G, Urrutia R, Iovanna JL) Cell Death Differ 2014 Oct;21(10):1633-41 40 Citations |
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| 1 | Reduction in ATP levels triggers immunoproteasome activation by the 11S (PA28) regulator during early antiviral response mediated by IFNβ in mouse pancreatic β-cells. (Freudenburg W, Gautam M, Chakraborty P, James J, Richards J, Salvatori AS, Baldwin A, Schriewer J, Buller RM, Corbett JA, Skowyra D) PLoS One 2013;8(2):e52408 22 Citations |
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| 1 | Adoptive transfer of Tc1 or Tc17 cells elicits antitumor immunity against established melanoma through distinct mechanisms. (Yu Y, Cho HI, Wang D, Kaosaard K, Anasetti C, Celis E, Yu XZ) J Immunol 2013 Feb 15;190(4):1873-81 54 Citations |
| 2 | Modulation of B-cell tolerance by murine gammaherpesvirus 68 infection: requirement for Orf73 viral gene expression and follicular helper T cells. (Gauld SB, De Santis JL, Kulinski JM, McGraw JA, Leonardo SM, Ruder EA, Maier W, Tarakanova VL) Immunology 2013 Jun;139(2):197-204 16 Citations |
| 1 | Enzyme replacement therapy rescues weakness and improves muscle pathology in mice with X-linked myotubular myopathy. (Lawlor MW, Armstrong D, Viola MG, Widrick JJ, Meng H, Grange RW, Childers MK, Hsu CP, O'Callaghan M, Pierson CR, Buj-Bello A, Beggs AH) Hum Mol Genet 2013 Apr 15;22(8):1525-38 68 Citations |
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| 1 | Mast cell activation and neutrophil recruitment promotes early and robust inflammation in the meninges in EAE. (Christy AL, Walker ME, Hessner MJ, Brown MA) J Autoimmun 2013 May;42:50-61 136 Citations |
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| 1 | Fluid flow shear stress upregulates prostanoid receptor EP2 but not EP4 in murine podocytes. (Srivastava T, McCarthy ET, Sharma R, Kats A, Carlton CG, Alon US, Cudmore PA, El-Meanawy A, Sharma M) Prostaglandins Other Lipid Mediat 2013;104-105:49-57 23 Citations |
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| 1 | Th17 cells confer long-term adaptive immunity to oral mucosal Candida albicans infections. (Hernández-Santos N, Huppler AR, Peterson AC, Khader SA, McKenna KC, Gaffen SL) Mucosal Immunol 2013 Sep;6(5):900-10 152 Citations |
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| 1 | Transient repetitive exposure to low level light therapy enhances collateral blood vessel growth in the ischemic hindlimb of the tight skin mouse. (Zaidi M, Krolikowki JG, Jones DW, Pritchard KA Jr, Struve J, Nandedkar SD, Lohr NL, Pagel PS, Weihrauch D) Photochem Photobiol 2013;89(3):709-13 18 Citations |
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| 1 | ADAM17 transactivates EGFR signaling during embryonic eyelid closure. (Hassemer EL, Endres B, Toonen JA, Ronchetti A, Dubielzig R, Sidjanin DJ) Invest Ophthalmol Vis Sci 2013 Jan 07;54(1):132-40 15 Citations |
| 1 | Examining T cells at vaccine sites of tumor-bearing hosts provides insights to dysfunctional T-cell immunity. (Barr KM, Jing W, Hallett WH, Gershan JA, Johnson BD) J Immunother 2013 Jan;36(1):41-51 2 Citations |
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| 1 | Netrin-1 promotes glioblastoma cell invasiveness and angiogenesis by multiple pathways including activation of RhoA, cathepsin B, and cAMP-response element-binding protein. (Shimizu A, Nakayama H, Wang P, König C, Akino T, Sandlund J, Coma S, Italiano JE Jr, Mammoto A, Bielenberg DR, Klagsbrun M) J Biol Chem 2013 Jan 25;288(4):2210-22 89 Citations |
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| 1 | Nipah virus envelope-pseudotyped lentiviruses efficiently target ephrinB2-positive stem cell populations in vitro and bypass the liver sink when administered in vivo. (Palomares K, Vigant F, Van Handel B, Pernet O, Chikere K, Hong P, Sherman SP, Patterson M, An DS, Lowry WE, Mikkola HK, Morizono K, Pyle AD, Lee B) J Virol 2013 Feb;87(4):2094-108 33 Citations |
| 1 | Glycosylation-independent lysosomal targeting of acid α-glucosidase enhances muscle glycogen clearance in pompe mice. (Maga JA, Zhou J, Kambampati R, Peng S, Wang X, Bohnsack RN, Thomm A, Golata S, Tom P, Dahms NM, Byrne BJ, LeBowitz JH) J Biol Chem 2013 Jan 18;288(3):1428-38 90 Citations |
| 1 | Capturing microRNA targets using an RNA-induced silencing complex (RISC)-trap approach. (Cambronne XA, Shen R, Auer PL, Goodman RH) Proc Natl Acad Sci U S A 2012 Dec 11;109(50):20473-8 51 Citations |
| 1 | COPI transport complexes bind to specific RNAs in neuronal cells. (Todd AG, Lin H, Ebert AD, Liu Y, Androphy EJ) Hum Mol Genet 2013 Feb 15;22(4):729-36 41 Citations |
| 2 | CD36 and Na/K-ATPase-α1 form a proinflammatory signaling loop in kidney. (Kennedy DJ, Chen Y, Huang W, Viterna J, Liu J, Westfall K, Tian J, Bartlett DJ, Tang WH, Xie Z, Shapiro JI, Silverstein RL) Hypertension 2013 Jan;61(1):216-24 86 Citations |
| 1 | HDAC6 regulates epidermal growth factor receptor (EGFR) endocytic trafficking and degradation in renal epithelial cells. (Liu W, Fan LX, Zhou X, Sweeney WE Jr, Avner ED, Li X) PLoS One 2012;7(11):e49418 68 Citations |
| 1 | Aging differentially affects the re-entrainment response of central and peripheral circadian oscillators. (Sellix MT, Evans JA, Leise TL, Castanon-Cervantes O, Hill DD, DeLisser P, Block GD, Menaker M, Davidson AJ) J Neurosci 2012 Nov 14;32(46):16193-202 128 Citations |
| 1 | SMB myosin heavy chain knockout enhances tonic contraction and reduces the rate of force generation in ileum and stomach antrum. (Huang Q, Babu GJ, Periasamy M, Eddinger TJ) Am J Physiol Cell Physiol 2013 Jan 15;304(2):C194-206 7 Citations |
| 1 | TRPA1 is functionally expressed primarily by IB4-binding, non-peptidergic mouse and rat sensory neurons. (Barabas ME, Kossyreva EA, Stucky CL) PLoS One 2012;7(10):e47988 88 Citations |
| 1 | Tie2(+) bone marrow endothelial cells regulate hematopoietic stem cell regeneration following radiation injury. (Doan PL, Russell JL, Himburg HA, Helms K, Harris JR, Lucas J, Holshausen KC, Meadows SK, Daher P, Jeffords LB, Chao NJ, Kirsch DG, Chute JP) Stem Cells 2013 Feb;31(2):327-37 61 Citations |
| 2 | A novel hemoglobin-binding peptide reduces cell-free hemoglobin in murine hemolytic anemia. (Hanson MS, Xu H, Flewelen TC, Holzhauer SL, Retherford D, Jones DW, Frei AC, Pritchard KA Jr, Hillery CA, Hogg N, Wandersee NJ) Am J Physiol Heart Circ Physiol 2013 Jan 15;304(2):H328-36 12 Citations |
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| 1 | Francisella tularensis live vaccine strain folate metabolism and pseudouridine synthase gene mutants modulate macrophage caspase-1 activation. (Ulland TK, Janowski AM, Buchan BW, Faron M, Cassel SL, Jones BD, Sutterwala FS) Infect Immun 2013 Jan;81(1):201-8 13 Citations |
| 2 | Patients with sickle cell disease have increased sensitivity to cold and heat. (Brandow AM, Stucky CL, Hillery CA, Hoffmann RG, Panepinto JA) Am J Hematol 2013 Jan;88(1):37-43 126 Citations |
| 1 | Cytochrome P450 1B1 gene disruption minimizes deoxycorticosterone acetate-salt-induced hypertension and associated cardiac dysfunction and renal damage in mice. (Jennings BL, Estes AM, Anderson LJ, Fang XR, Yaghini FA, Fan Z, Gonzalez FJ, Campbell WB, Malik KU) Hypertension 2012 Dec;60(6):1510-6 26 Citations |
| 1 | Interactions of the human LIP5 regulatory protein with endosomal sorting complexes required for transport. (Skalicky JJ, Arii J, Wenzel DM, Stubblefield WM, Katsuyama A, Uter NT, Bajorek M, Myszka DG, Sundquist WI) J Biol Chem 2012 Dec 21;287(52):43910-26 38 Citations |
| 1 | Anti-inflammatory and neuroprotective effects of an orally active apocynin derivative in pre-clinical models of Parkinson's disease. (Ghosh A, Kanthasamy A, Joseph J, Anantharam V, Srivastava P, Dranka BP, Kalyanaraman B, Kanthasamy AG) J Neuroinflammation 2012 Oct 23;9:241 97 Citations |
| 1 | Pleiotrophin regulates the retention and self-renewal of hematopoietic stem cells in the bone marrow vascular niche. (Himburg HA, Harris JR, Ito T, Daher P, Russell JL, Quarmyne M, Doan PL, Helms K, Nakamura M, Fixsen E, Herradon G, Reya T, Chao NJ, Harroch S, Chute JP) Cell Rep 2012 Oct 25;2(4):964-75 87 Citations |
| 1 | Critical role of B cell lymphoma 10 in BAFF-regulated NF-κB activation and survival of anergic B cells. (Yu M, Chen Y, He Y, Podd A, Fu G, Wright JA, Kleiman E, Khan WN, Wen R, Wang D) J Immunol 2012 Dec 01;189(11):5185-93 17 Citations |
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| 1 | The compensatory G88R change is essential in restoring the normal functions of influenza A/WSN/33 virus matrix protein 1 with a disrupted nuclear localization signal. (Xie H, Lin Z, Mosier PD, Desai UR, Gao Y) J Virol 2013 Jan;87(1):345-53 9 Citations |
| 1 | Toll-like receptor 2 ligands promote microglial cell death by inducing autophagy. (Arroyo DS, Soria JA, Gaviglio EA, Garcia-Keller C, Cancela LM, Rodriguez-Galan MC, Wang JM, Iribarren P) FASEB J 2013 Jan;27(1):299-312 44 Citations |
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| 1 | Baicalein abrogates reactive oxygen species (ROS)-mediated mitochondrial dysfunction during experimental pulmonary carcinogenesis in vivo. (Naveenkumar C, Raghunandhakumar S, Asokkumar S, Devaki T) Basic Clin Pharmacol Toxicol 2013 Apr;112(4):270-81 38 Citations |
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| 1 | HMGB1 release by urothelial carcinoma cells is required for the in vivo antitumor response to Bacillus Calmette-Guérin. (Zhang G, Chen F, Cao Y, Johnson B, See WA) J Urol 2013 Apr;189(4):1541-6 7 Citations |
| 2 | Cullin-3 regulates vascular smooth muscle function and arterial blood pressure via PPARγ and RhoA/Rho-kinase. (Pelham CJ, Ketsawatsomkron P, Groh S, Grobe JL, de Lange WJ, Ibeawuchi SR, Keen HL, Weatherford ET, Faraci FM, Sigmund CD) Cell Metab 2012 Oct 03;16(4):462-72 86 Citations |
| 1 | Striatal adenosine signaling regulates EAAT2 and astrocytic AQP4 expression and alcohol drinking in mice. (Lee MR, Ruby CL, Hinton DJ, Choi S, Adams CA, Young Kang N, Choi DS) Neuropsychopharmacology 2013 Feb;38(3):437-45 53 Citations |
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| 1 | The transition state analog inhibitor of Purine Nucleoside Phosphorylase (PNP) Immucillin-H arrests bone loss in rat periodontal disease models. (Deves C, de Assunção TM, Ducati RG, Campos MM, Basso LA, Santos DS, Batista EL Jr) Bone 2013 Jan;52(1):167-75 6 Citations |
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| 1 | Modulation of function of sodium-dependent vitamin C transporter 1 (SVCT1) by Rab8a in intestinal epithelial cells: studies utilizing Caco-2 cells and Rab8a knockout mice. (Subramanian VS, Subramanya SB, Ghosal A, Marchant JS, Harada A, Said HM) Dig Dis Sci 2013 Mar;58(3):641-9 10 Citations |
| 1 | Prostaglandin metabolite induces inhibition of TRPA1 and channel-dependent nociception. (Weng Y, Batista-Schepman PA, Barabas ME, Harris EQ, Dinsmore TB, Kossyreva EA, Foshage AM, Wang MH, Schwab MJ, Wang VM, Stucky CL, Story GM) Mol Pain 2012 Sep 27;8:75 22 Citations |
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| 1 | Neonatal transfer of membrane-bound stem cell factor improves survival and heart function in aged mice after myocardial ischemia. (Sun Z, Lee CJ, Mejia-Guerrero S, Zhang Y, Higuchi K, Li RK, Medin JA) Hum Gene Ther 2012 Dec;23(12):1280-9 4 Citations |
| 1 | Comparison of methods to control floor contamination in an animal research facility. (Allen KP, Csida T, Leming J, Murray K, Gauld SB, Thulin J) Lab Anim (NY) 2012 Oct;41(10):282-8 9 Citations |
| 1 | Ataxia telangiectasia mutated kinase controls chronic gammaherpesvirus infection. (Kulinski JM, Leonardo SM, Mounce BC, Malherbe L, Gauld SB, Tarakanova VL) J Virol 2012 Dec;86(23):12826-37 33 Citations |
| 1 | The FGFR4-G388R single-nucleotide polymorphism alters pancreatic neuroendocrine tumor progression and response to mTOR inhibition therapy. (Serra S, Zheng L, Hassan M, Phan AT, Woodhouse LJ, Yao JC, Ezzat S, Asa SL) Cancer Res 2012 Nov 15;72(22):5683-91 45 Citations |
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| 1 | Precise control of osteogenesis for craniofacial defect repair: the role of direct osteoprogenitor contact in BMP-2-based bioprinting. (Smith DM, Cray JJ Jr, Weiss LE, Dai Fei EK, Shakir S, Rottgers SA, Losee JE, Campbell PG, Cooper GM) Ann Plast Surg 2012 Oct;69(4):485-8 26 Citations |
| 2 | Sickle cell mice exhibit mechanical allodynia and enhanced responsiveness in light touch cutaneous mechanoreceptors. (Garrison SR, Kramer AA, Gerges NZ, Hillery CA, Stucky CL) Mol Pain 2012 Sep 10;8:62 45 Citations |
| 2 | PPARγ regulates resistance vessel tone through a mechanism involving RGS5-mediated control of protein kinase C and BKCa channel activity. (Ketsawatsomkron P, Lorca RA, Keen HL, Weatherford ET, Liu X, Pelham CJ, Grobe JL, Faraci FM, England SK, Sigmund CD) Circ Res 2012 Nov 09;111(11):1446-58 54 Citations |
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| 1 | MED25 is a mediator component of HNF4α-driven transcription leading to insulin secretion in pancreatic beta-cells. (Han EH, Rha GB, Chi YI) PLoS One 2012;7(8):e44007 13 Citations |
| 1 | Reductive stress linked to small HSPs, G6PD, and Nrf2 pathways in heart disease. (Brewer AC, Mustafi SB, Murray TV, Rajasekaran NS, Benjamin IJ) Antioxid Redox Signal 2013 Mar 20;18(9):1114-27 104 Citations |
| 1 | Biomarkers of response to Akt inhibitor MK-2206 in breast cancer. (Sangai T, Akcakanat A, Chen H, Tarco E, Wu Y, Do KA, Miller TW, Arteaga CL, Mills GB, Gonzalez-Angulo AM, Meric-Bernstam F) Clin Cancer Res 2012 Oct 15;18(20):5816-28 138 Citations |
| 1 | The C-type natriuretic peptide induces thermal hyperalgesia through a noncanonical Gβγ-dependent modulation of TRPV1 channel. (Loo L, Shepherd AJ, Mickle AD, Lorca RA, Shutov LP, Usachev YM, Mohapatra DP) J Neurosci 2012 Aug 29;32(35):11942-55 41 Citations |
| 1 | The TCR repertoires of regulatory and conventional T cells specific for the same foreign antigen are distinct. (Relland LM, Williams JB, Relland GN, Haribhai D, Ziegelbauer J, Yassai M, Gorski J, Williams CB) J Immunol 2012 Oct 01;189(7):3566-74 24 Citations |
| 1 | Waved with open eyelids 2 (woe2) is a novel spontaneous mouse mutation in the protein phosphatase 1, regulatory (inhibitor) subunit 13 like (Ppp1r13l) gene. (Toonen J, Liang L, Sidjanin DJ) BMC Genet 2012 Aug 28;13:76 19 Citations |
| 1 | TRPA1 mediates mechanical sensitization in nociceptors during inflammation. (Lennertz RC, Kossyreva EA, Smith AK, Stucky CL) PLoS One 2012;7(8):e43597 135 Citations |
| 1 | Mechanistic basis for overcoming platinum resistance using copper chelating agents. (Liang ZD, Long Y, Tsai WB, Fu S, Kurzrock R, Gagea-Iurascu M, Zhang F, Chen HH, Hennessy BT, Mills GB, Savaraj N, Kuo MT) Mol Cancer Ther 2012 Nov;11(11):2483-94 70 Citations |
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| 1 | Collagen XIV is important for growth and structural integrity of the myocardium. (Tao G, Levay AK, Peacock JD, Huk DJ, Both SN, Purcell NH, Pinto JR, Galantowicz ML, Koch M, Lucchesi PA, Birk DE, Lincoln J) J Mol Cell Cardiol 2012 Nov;53(5):626-38 59 Citations |
| 1 | E2F7 and E2F8 promote angiogenesis through transcriptional activation of VEGFA in cooperation with HIF1. (Weijts BG, Bakker WJ, Cornelissen PW, Liang KH, Schaftenaar FH, Westendorp B, de Wolf CA, Paciejewska M, Scheele CL, Kent L, Leone G, Schulte-Merker S, de Bruin A) EMBO J 2012 Oct 03;31(19):3871-84 107 Citations |
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| 1 | Neuroinflammation by cytotoxic T-lymphocytes impairs retrograde axonal transport in an oligodendrocyte mutant mouse. (Ip CW, Kroner A, Groh J, Huber M, Klein D, Spahn I, Diem R, Williams SK, Nave KA, Edgar JM, Martini R) PLoS One 2012;7(8):e42554 29 Citations |
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| 1 | Interleukin-15 plays an essential role in the pathogenesis of autoimmune diabetes in the NOD mouse. (Bobbala D, Chen XL, Leblanc C, Mayhue M, Stankova J, Tanaka T, Chen YG, Ilangumaran S, Ramanathan S) Diabetologia 2012 Nov;55(11):3010-20 34 Citations |
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| 1 | Biological responses to TGF-β in the mammary epithelium show a complex dependency on Smad3 gene dosage with important implications for tumor progression. (Kohn EA, Yang YA, Du Z, Nagano Y, Van Schyndle CM, Herrmann MA, Heldman M, Chen JQ, Stuelten CH, Flanders KC, Wakefield LM) Mol Cancer Res 2012 Oct;10(10):1389-99 20 Citations |
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| 1 | Myotubularin-deficient myoblasts display increased apoptosis, delayed proliferation, and poor cell engraftment. (Lawlor MW, Alexander MS, Viola MG, Meng H, Joubert R, Gupta V, Motohashi N, Manfready RA, Hsu CP, Huang P, Buj-Bello A, Kunkel LM, Beggs AH, Gussoni E) Am J Pathol 2012 Sep;181(3):961-8 34 Citations |
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| 2 | Homotypic cell cannibalism, a cell-death process regulated by the nuclear protein 1, opposes to metastasis in pancreatic cancer. (Cano CE, Sandí MJ, Hamidi T, Calvo EL, Turrini O, Bartholin L, Loncle C, Secq V, Garcia S, Lomberk G, Kroemer G, Urrutia R, Iovanna JL) EMBO Mol Med 2012 Sep;4(9):964-79 65 Citations |
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| 2 | The β₃-integrin ligand of Borrelia burgdorferi is critical for infection of mice but not ticks. (Ristow LC, Miller HE, Padmore LJ, Chettri R, Salzman N, Caimano MJ, Rosa PA, Coburn J) Mol Microbiol 2012 Sep;85(6):1105-18 50 Citations |
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| 1 | MprA and DosR coregulate a Mycobacterium tuberculosis virulence operon encoding Rv1813c and Rv1812c. (Bretl DJ, He H, Demetriadou C, White MJ, Penoske RM, Salzman NH, Zahrt TC) Infect Immun 2012 Sep;80(9):3018-33 39 Citations |
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| 1 | The progesterone-induced enhancement of object recognition memory consolidation involves activation of the extracellular signal-regulated kinase (ERK) and mammalian target of rapamycin (mTOR) pathways in the dorsal hippocampus. (Orr PT, Rubin AJ, Fan L, Kent BA, Frick KM) Horm Behav 2012 Apr;61(4):487-95 36 Citations |
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| 1 | Mechanism and kinetics of inducible nitric oxide synthase auto-S-nitrosation and inactivation. (Smith BC, Fernhoff NB, Marletta MA) Biochemistry 2012 Feb 07;51(5):1028-40 31 Citations |
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| 1 | Pathway-specific analysis of gene expression data identifies the PI3K/Akt pathway as a novel therapeutic target in cervical cancer. (Schwarz JK, Payton JE, Rashmi R, Xiang T, Jia Y, Huettner P, Rogers BE, Yang Q, Watson M, Rader JS, Grigsby PW) Clin Cancer Res 2012 Mar 01;18(5):1464-71 97 Citations |
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| 1 | Opioid-induced hypernociception is associated with hyperexcitability and altered tetrodotoxin-resistant Na+ channel function of dorsal root ganglia. (Ross GR, Gade AR, Dewey WL, Akbarali HI) Am J Physiol Cell Physiol 2012 Apr 15;302(8):C1152-61 22 Citations |
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| 2 | Epoxyeicosanoids stimulate multiorgan metastasis and tumor dormancy escape in mice. (Panigrahy D, Edin ML, Lee CR, Huang S, Bielenberg DR, Butterfield CE, Barnés CM, Mammoto A, Mammoto T, Luria A, Benny O, Chaponis DM, Dudley AC, Greene ER, Vergilio JA, Pietramaggiori G, Scherer-Pietramaggiori SS, Short SM, Seth M, Lih FB, Tomer KB, Yang J, Schwendener RA, Hammock BD, Falck JR, Manthati VL, Ingber DE, Kaipainen A, D'Amore PA, Kieran MW, Zeldin DC) J Clin Invest 2012 Jan;122(1):178-91 258 Citations |
| 2 | Reprogramming of the tumour microenvironment by stromal PTEN-regulated miR-320. (Bronisz A, Godlewski J, Wallace JA, Merchant AS, Nowicki MO, Mathsyaraja H, Srinivasan R, Trimboli AJ, Martin CK, Li F, Yu L, Fernandez SA, Pécot T, Rosol TJ, Cory S, Hallett M, Park M, Piper MG, Marsh CB, Yee LD, Jimenez RE, Nuovo G, Lawler SE, Chiocca EA, Leone G, Ostrowski MC) Nat Cell Biol 2011 Dec 18;14(2):159-67 250 Citations |
| 1 | The receptor tyrosine kinase ErbB3 maintains the balance between luminal and basal breast epithelium. (Balko JM, Miller TW, Morrison MM, Hutchinson K, Young C, Rinehart C, Sánchez V, Jee D, Polyak K, Prat A, Perou CM, Arteaga CL, Cook RS) Proc Natl Acad Sci U S A 2012 Jan 03;109(1):221-6 57 Citations |
| 1 | GPIbα regulates platelet size by controlling the subcellular localization of filamin. (Kanaji T, Ware J, Okamura T, Newman PJ) Blood 2012 Mar 22;119(12):2906-13 51 Citations |
| 1 | Limited effects of bile acids and small heterodimer partner on hepatitis B virus biosynthesis in vivo. (Reese VC, Moore DD, McLachlan A) J Virol 2012 Mar;86(5):2760-8 19 Citations |
| 1 | A mouse model of lamellar intrastromal femtosecond laser keratotomy: ultra-structural, inflammatory, and wound healing responses. (Angunawela RI, Poh R, Chaurasia SS, Tan DT, Mehta JS) Mol Vis 2011;17:3005-12 11 Citations |
| 1 | Optimization of in vivo confocal autofluorescence imaging of the ocular fundus in mice and its application to models of human retinal degeneration. (Charbel Issa P, Singh MS, Lipinski DM, Chong NV, Delori FC, Barnard AR, MacLaren RE) Invest Ophthalmol Vis Sci 2012 Feb;53(2):1066-75 57 Citations |
| 1 | Combining M-FISH and Quantum Dot technology for fast chromosomal assignment of transgenic insertions. (Yusuf M, Bauer DL, Lipinski DM, MacLaren RE, Wade-Martins R, Mir KU, Volpi EV) BMC Biotechnol 2011 Dec 13;11:121 5 Citations |
| 1 | S100A7 enhances mammary tumorigenesis through upregulation of inflammatory pathways. (Nasser MW, Qamri Z, Deol YS, Ravi J, Powell CA, Trikha P, Schwendener RA, Bai XF, Shilo K, Zou X, Leone G, Wolf R, Yuspa SH, Ganju RK) Cancer Res 2012 Feb 01;72(3):604-15 103 Citations |
| 1 | Functional analysis of the Hsf4(lop11) allele responsible for cataracts in lop11 mice. (Liang L, Liegel R, Endres B, Ronchetti A, Chang B, Sidjanin DJ) Mol Vis 2011;17:3062-71 6 Citations |
| 1 | Global gene expression profiling in mouse plasma cell tumor precursor and bystander cells reveals potential intervention targets for plasma cell neoplasia. (LeGrand J, Park ES, Wang H, Gupta S, Owens JD Jr, Nelson PJ, DuBois W, Bair T, Janz S, Mushinski JF) Blood 2012 Jan 26;119(4):1018-28 6 Citations |
| 3 | Global profiling of reactive oxygen and nitrogen species in biological systems: high-throughput real-time analyses. (Zielonka J, Zielonka M, Sikora A, Adamus J, Joseph J, Hardy M, Ouari O, Dranka BP, Kalyanaraman B) J Biol Chem 2012 Jan 27;287(5):2984-95 163 Citations |
| 1 | Effect of nicotine on body composition in mice. (Mangubat M, Lutfy K, Lee ML, Pulido L, Stout D, Davis R, Shin CS, Shahbazian M, Seasholtz S, Sinha-Hikim A, Sinha-Hikim I, O'Dell LE, Lyzlov A, Liu Y, Friedman TC) J Endocrinol 2012 Mar;212(3):317-26 54 Citations |
| 1 | The PDL1-PD1 axis converts human TH1 cells into regulatory T cells. (Amarnath S, Mangus CW, Wang JC, Wei F, He A, Kapoor V, Foley JE, Massey PR, Felizardo TC, Riley JL, Levine BL, June CH, Medin JA, Fowler DH) Sci Transl Med 2011 Nov 30;3(111):111ra120 371 Citations |
| 1 | Using ChIPMotifs for de novo motif discovery of OCT4 and ZNF263 based on ChIP-based high-throughput experiments. (Kennedy BA, Lan X, Huang TH, Farnham PJ, Jin VX) Methods Mol Biol 2012;802:323-34 3 Citations |
| 1 | The role of β-arrestin2 in the mechanism of morphine tolerance in the mouse and guinea pig gastrointestinal tract. (Kang M, Maguma HT, Smith TH, Ross GR, Dewey WL, Akbarali HI) J Pharmacol Exp Ther 2012 Mar;340(3):567-76 52 Citations |
| 2 | Mitochondrial-targeted antioxidants represent a promising approach for prevention of cisplatin-induced nephropathy. (Mukhopadhyay P, Horváth B, Zsengellér Z, Zielonka J, Tanchian G, Holovac E, Kechrid M, Patel V, Stillman IE, Parikh SM, Joseph J, Kalyanaraman B, Pacher P) Free Radic Biol Med 2012 Jan 15;52(2):497-506 184 Citations |
| 3 | PECAM-1 dampens cytokine levels during LPS-induced endotoxemia by regulating leukocyte trafficking. (Privratsky JR, Tilkens SB, Newman DK, Newman PJ) Life Sci 2012 Jan 30;90(5-6):177-84 15 Citations |
| 1 | HSF1-dependent upregulation of Hsp70 by sulfhydryl-reactive inducers of the KEAP1/NRF2/ARE pathway. (Zhang Y, Ahn YH, Benjamin IJ, Honda T, Hicks RJ, Calabrese V, Cole PA, Dinkova-Kostova AT) Chem Biol 2011 Nov 23;18(11):1355-61 97 Citations |
| 1 | Photoaffinity labeling of nicotinic acid adenine dinucleotide phosphate (NAADP) targets in mammalian cells. (Lin-Moshier Y, Walseth TF, Churamani D, Davidson SM, Slama JT, Hooper R, Brailoiu E, Patel S, Marchant JS) J Biol Chem 2012 Jan 20;287(4):2296-307 140 Citations |
| 1 | The hexosamine biosynthetic pathway and O-GlcNAcylation drive the expression of β-catenin and cell proliferation. (Olivier-Van Stichelen S, Guinez C, Mir AM, Perez-Cervera Y, Liu C, Michalski JC, Lefebvre T) Am J Physiol Endocrinol Metab 2012 Feb 15;302(4):E417-24 59 Citations |
| 2 | Desialylation accelerates platelet clearance after refrigeration and initiates GPIbα metalloproteinase-mediated cleavage in mice. (Jansen AJ, Josefsson EC, Rumjantseva V, Liu QP, Falet H, Bergmeier W, Cifuni SM, Sackstein R, von Andrian UH, Wagner DD, Hartwig JH, Hoffmeister KM) Blood 2012 Feb 02;119(5):1263-73 171 Citations |
| 1 | Recruitment of endophilin to clathrin-coated pit necks is required for efficient vesicle uncoating after fission. (Milosevic I, Giovedi S, Lou X, Raimondi A, Collesi C, Shen H, Paradise S, O'Toole E, Ferguson S, Cremona O, De Camilli P) Neuron 2011 Nov 17;72(4):587-601 269 Citations |
| 1 | Granzyme B regulates antiviral CD8+ T cell responses. (Salti SM, Hammelev EM, Grewal JL, Reddy ST, Zemple SJ, Grossman WJ, Grayson MH, Verbsky JW) J Immunol 2011 Dec 15;187(12):6301-9 69 Citations |
| 1 | Oxidation of CaMKII determines the cardiotoxic effects of aldosterone. (He BJ, Joiner ML, Singh MV, Luczak ED, Swaminathan PD, Koval OM, Kutschke W, Allamargot C, Yang J, Guan X, Zimmerman K, Grumbach IM, Weiss RM, Spitz DR, Sigmund CD, Blankesteijn WM, Heymans S, Mohler PJ, Anderson ME) Nat Med 2011 Nov 13;17(12):1610-8 206 Citations |
| 1 | Reduction in number of sarcolemmal KATP channels slows cardiac action potential duration shortening under hypoxia. (Zhu Z, Burnett CM, Maksymov G, Stepniak E, Sierra A, Subbotina E, Anderson ME, Coetzee WA, Hodgson-Zingman DM, Zingman LV) Biochem Biophys Res Commun 2011 Dec 02;415(4):637-41 17 Citations |
| 2 | Cytochrome c-mediated formation of S-nitrosothiol in cells. (Broniowska KA, Keszler A, Basu S, Kim-Shapiro DB, Hogg N) Biochem J 2012 Feb 15;442(1):191-7 37 Citations |
| 1 | TRPC1 contributes to light-touch sensation and mechanical responses in low-threshold cutaneous sensory neurons. (Garrison SR, Dietrich A, Stucky CL) J Neurophysiol 2012 Feb;107(3):913-22 73 Citations |
| 1 | Modeling the human MTM1 p.R69C mutation in murine Mtm1 results in exon 4 skipping and a less severe myotubular myopathy phenotype. (Pierson CR, Dulin-Smith AN, Durban AN, Marshall ML, Marshall JT, Snyder AD, Naiyer N, Gladman JT, Chandler DS, Lawlor MW, Buj-Bello A, Dowling JJ, Beggs AH) Hum Mol Genet 2012 Feb 15;21(4):811-25 49 Citations |
| 1 | Bilateral inhibition of HAUSP deubiquitinase by a viral interferon regulatory factor protein. (Lee HR, Choi WC, Lee S, Hwang J, Hwang E, Guchhait K, Haas J, Toth Z, Jeon YH, Oh TK, Kim MH, Jung JU) Nat Struct Mol Biol 2011 Nov 06;18(12):1336-44 71 Citations |
| 1 | Divergent mechanism regulating fluid intake and metabolism by the brain renin-angiotensin system. (Sigmund CD) Am J Physiol Regul Integr Comp Physiol 2012 Feb 01;302(3):R313-20 17 Citations |
| 1 | ERα-dependent E2F transcription can mediate resistance to estrogen deprivation in human breast cancer. (Miller TW, Balko JM, Fox EM, Ghazoui Z, Dunbier A, Anderson H, Dowsett M, Jiang A, Smith RA, Maira SM, Manning HC, González-Angulo AM, Mills GB, Higham C, Chanthaphaychith S, Kuba MG, Miller WR, Shyr Y, Arteaga CL) Cancer Discov 2011 Sep;1(4):338-51 278 Citations |
| 1 | Sox9 transcriptionally represses Spp1 to prevent matrix mineralization in maturing heart valves and chondrocytes. (Peacock JD, Huk DJ, Ediriweera HN, Lincoln J) PLoS One 2011;6(10):e26769 40 Citations |
| 1 | Correction of murine Bernard-Soulier syndrome by lentivirus-mediated gene therapy. (Kanaji S, Kuether EL, Fahs SA, Schroeder JA, Ware J, Montgomery RR, Shi Q) Mol Ther 2012 Mar;20(3):625-32 30 Citations |
| 2 | Polyamidoamine (PAMAM) dendrimer conjugate specifically activates the A3 adenosine receptor to improve post-ischemic/reperfusion function in isolated mouse hearts. (Wan TC, Tosh DK, Du L, Gizewski ET, Jacobson KA, Auchampach JA) BMC Pharmacol 2011 Oct 31;11:11 27 Citations |
| 1 | Nitroglycerin drives endothelial nitric oxide synthase activation via the phosphatidylinositol 3-kinase/protein kinase B pathway. (Mao M, Sudhahar V, Ansenberger-Fricano K, Fernandes DC, Tanaka LY, Fukai T, Laurindo FR, Mason RP, Vasquez-Vivar J, Minshall RD, Stadler K, Bonini MG) Free Radic Biol Med 2012 Jan 15;52(2):427-35 22 Citations |
| 1 | Effects of experimental asthma on inflammation and lung mechanics in sickle cell mice. (Pritchard KA Jr, Feroah TR, Nandedkar SD, Holzhauer SL, Hutchins W, Schulte ML, Strunk RC, Debaun MR, Hillery CA) Am J Respir Cell Mol Biol 2012 Mar;46(3):389-96 25 Citations |
| 1 | NAD(P)H oxidase and eNOS play differential roles in cytomegalovirus infection-induced microvascular dysfunction. (Leskov IL, Whitsett J, Vasquez-Vivar J, Stokes KY) Free Radic Biol Med 2011 Dec 15;51(12):2300-8 15 Citations |
| 1 | Sequence-specific capture of protein-DNA complexes for mass spectrometric protein identification. (Wu CH, Chen S, Shortreed MR, Kreitinger GM, Yuan Y, Frey BL, Zhang Y, Mirza S, Cirillo LA, Olivier M, Smith LM) PLoS One 2011;6(10):e26217 25 Citations |
| 1 | The retinoblastoma tumor suppressor regulates a xenobiotic detoxification pathway. (Sáenz Robles MT, Case A, Chong JL, Leone G, Pipas JM) PLoS One 2011;6(10):e26019 5 Citations |
| 2 | Dynamic association of gammaherpesvirus DNA with core histone during de novo lytic infection of primary cells. (Mounce BC, Tsan FC, Kohler S, Cirillo LA, Tarakanova VL) Virology 2011 Dec 20;421(2):167-72 14 Citations |
| 1 | Neutrophils are required for 3-methylcholanthrene-initiated, butylated hydroxytoluene-promoted lung carcinogenesis. (Vikis HG, Gelman AE, Franklin A, Stein L, Rymaszewski A, Zhu J, Liu P, Tichelaar JW, Krupnick AS, You M) Mol Carcinog 2012 Dec;51(12):993-1002 22 Citations |
| 1 | Expansion of Paneth cell population in response to enteric Salmonella enterica serovar Typhimurium infection. (Martinez Rodriguez NR, Eloi MD, Huynh A, Dominguez T, Lam AH, Carcamo-Molina D, Naser Z, Desharnais R, Salzman NH, Porter E) Infect Immun 2012 Jan;80(1):266-75 57 Citations |
| 1 | An in vivo rodent model of contraction-induced injury in the quadriceps muscle. (Pratt SJP, Lawlor MW, Shah SB, Lovering RM) Injury 2012 Jun;43(6):788-93 21 Citations |
| 1 | Ccr5 regulates inflammatory gene expression in response to encephalomyocarditis virus infection. (Christmann BS, Moran JM, McGraw JA, Buller RM, Corbett JA) Am J Pathol 2011 Dec;179(6):2941-51 17 Citations |
| 1 | Positional cloning of a type 2 diabetes quantitative trait locus; tomosyn-2, a negative regulator of insulin secretion. (Bhatnagar S, Oler AT, Rabaglia ME, Stapleton DS, Schueler KL, Truchan NA, Worzella SL, Stoehr JP, Clee SM, Yandell BS, Keller MP, Thurmond DC, Attie AD) PLoS Genet 2011 Oct;7(10):e1002323 60 Citations |
| 1 | Physically associated synthetic hydrogels with long-term covalent stabilization for cell culture and stem cell transplantation. (Zhang J, Tokatlian T, Zhong J, Ng QK, Patterson M, Lowry WE, Carmichael ST, Segura T) Adv Mater 2011 Nov 16;23(43):5098-103 54 Citations |
| 1 | Non-parametric population analysis of cellular phenotypes. (Singh S, Janoos F, Pécot T, Caserta E, Huang K, Rittscher J, Leone G, Machiraju R) Med Image Comput Comput Assist Interv 2011;14(Pt 2):343-51 9 Citations |
| 2 | Cyclic AMP dysregulates intestinal epithelial cell restitution through PKA and RhoA. (Zimmerman NP, Kumar SN, Turner JR, Dwinell MB) Inflamm Bowel Dis 2012 Jun;18(6):1081-91 34 Citations |
| 1 | (+)-Morphine attenuates the (-)-morphine-produced tail-flick inhibition via the sigma-1 receptor in the mouse spinal cord. (Tseng LF, Hogan QH, Wu HE) Life Sci 2011 Dec 05;89(23-24):875-7 10 Citations |
| 2 | Monomeric and dimeric CXCL12 inhibit metastasis through distinct CXCR4 interactions and signaling pathways. (Drury LJ, Ziarek JJ, Gravel S, Veldkamp CT, Takekoshi T, Hwang ST, Heveker N, Volkman BF, Dwinell MB) Proc Natl Acad Sci U S A 2011 Oct 25;108(43):17655-60 183 Citations |
| 1 | FGF23 induces left ventricular hypertrophy. (Faul C, Amaral AP, Oskouei B, Hu MC, Sloan A, Isakova T, Gutiérrez OM, Aguillon-Prada R, Lincoln J, Hare JM, Mundel P, Morales A, Scialla J, Fischer M, Soliman EZ, Chen J, Go AS, Rosas SE, Nessel L, Townsend RR, Feldman HI, St John Sutton M, Ojo A, Gadegbeku C, Di Marco GS, Reuter S, Kentrup D, Tiemann K, Brand M, Hill JA, Moe OW, Kuro-O M, Kusek JW, Keane MG, Wolf M) J Clin Invest 2011 Nov;121(11):4393-408 1718 Citations |
| 1 | Pulmonary hypertension in the newborn GTP cyclohydrolase I-deficient mouse. (Belik J, McIntyre BA, Enomoto M, Pan J, Grasemann H, Vasquez-Vivar J) Free Radic Biol Med 2011 Dec 15;51(12):2227-33 19 Citations |
| 1 | VSX2 mutations in autosomal recessive microphthalmia. (Reis LM, Khan A, Kariminejad A, Ebadi F, Tyler RC, Semina EV) Mol Vis 2011;17:2527-32 29 Citations |
| 1 | Wnt signaling mediates pathological vascular growth in proliferative retinopathy. (Chen J, Stahl A, Krah NM, Seaward MR, Dennison RJ, Sapieha P, Hua J, Hatton CJ, Juan AM, Aderman CM, Willett KL, Guerin KI, Mammoto A, Campbell M, Smith LE) Circulation 2011 Oct 25;124(17):1871-81 108 Citations |
| 1 | Optimization of hCFTR lung expression in mice using DNA nanoparticles. (Padegimas L, Kowalczyk TH, Adams S, Gedeon CR, Oette SM, Dines K, Hyatt SL, Sesenoglu-Laird O, Tyr O, Moen RC, Cooper MJ) Mol Ther 2012 Jan;20(1):63-72 31 Citations |
| 2 | Gammaherpesvirus gene expression and DNA synthesis are facilitated by viral protein kinase and histone variant H2AX. (Mounce BC, Tsan FC, Droit L, Kohler S, Reitsma JM, Cirillo LA, Tarakanova VL) Virology 2011 Nov 25;420(2):73-81 18 Citations |
| 1 | Dysfunctional HDL containing L159R ApoA-I leads to exacerbation of atherosclerosis in hyperlipidemic mice. (Sorci-Thomas MG, Zabalawi M, Bharadwaj MS, Wilhelm AJ, Owen JS, Asztalos BF, Bhat S, Thomas MJ) Biochim Biophys Acta 2012 Mar;1821(3):502-12 18 Citations |
| 1 | Chronic, noninvasive glucocorticoid administration suppresses limbic endocannabinoid signaling in mice. (Bowles NP, Hill MN, Bhagat SM, Karatsoreos IN, Hillard CJ, McEwen BS) Neuroscience 2012 Mar 01;204:83-9 53 Citations |
| 1 | Alterations of endocannabinoid signaling, synaptic plasticity, learning, and memory in monoacylglycerol lipase knock-out mice. (Pan B, Wang W, Zhong P, Blankman JL, Cravatt BF, Liu QS) J Neurosci 2011 Sep 21;31(38):13420-30 130 Citations |
| 2 | Distinct roles for Rap1b protein in platelet secretion and integrin αIIbβ3 outside-in signaling. (Zhang G, Xiang B, Ye S, Chrzanowska-Wodnicka M, Morris AJ, Gartner TK, Whiteheart SW, White GC 2nd, Smyth SS, Li Z) J Biol Chem 2011 Nov 11;286(45):39466-77 61 Citations |
| 2 | Genetic control of murine invariant natural killer T-cell development dynamically differs dependent on the examined tissue type. (Chen YG, Tsaih SW, Serreze DV) Genes Immun 2012 Feb;13(2):164-74 15 Citations |
| 1 | The identification of different endothelial cell populations within the mouse proepicardium. (Cossette S, Misra R) Dev Dyn 2011 Oct;240(10):2344-53 34 Citations |
| 2 | Mechanochemical control of mesenchymal condensation and embryonic tooth organ formation. (Mammoto T, Mammoto A, Torisawa YS, Tat T, Gibbs A, Derda R, Mannix R, de Bruijn M, Yung CW, Huh D, Ingber DE) Dev Cell 2011 Oct 18;21(4):758-69 163 Citations |
| 1 | Mmp15 is a direct target of Snai1 during endothelial to mesenchymal transformation and endocardial cushion development. (Tao G, Levay AK, Gridley T, Lincoln J) Dev Biol 2011 Nov 15;359(2):209-21 45 Citations |
| 1 | Genetic deletion of monoacylglycerol lipase alters endocannabinoid-mediated retrograde synaptic depression in the cerebellum. (Zhong P, Pan B, Gao XP, Blankman JL, Cravatt BF, Liu QS) J Physiol 2011 Oct 15;589(Pt 20):4847-55 55 Citations |
| 1 | A kinome-wide screen identifies the insulin/IGF-I receptor pathway as a mechanism of escape from hormone dependence in breast cancer. (Fox EM, Miller TW, Balko JM, Kuba MG, Sánchez V, Smith RA, Liu S, González-Angulo AM, Mills GB, Ye F, Shyr Y, Manning HC, Buck E, Arteaga CL) Cancer Res 2011 Nov 01;71(21):6773-84 138 Citations |
| 1 | An integrated in vitro and in vivo high-throughput screen identifies treatment leads for ependymoma. (Atkinson JM, Shelat AA, Carcaboso AM, Kranenburg TA, Arnold LA, Boulos N, Wright K, Johnson RA, Poppleton H, Mohankumar KM, Féau C, Phoenix T, Gibson P, Zhu L, Tong Y, Eden C, Ellison DW, Priebe W, Koul D, Yung WK, Gajjar A, Stewart CF, Guy RK, Gilbertson RJ) Cancer Cell 2011 Sep 13;20(3):384-99 96 Citations |
| 1 | Antitumor activity of the investigational proteasome inhibitor MLN9708 in mouse models of B-cell and plasma cell malignancies. (Lee EC, Fitzgerald M, Bannerman B, Donelan J, Bano K, Terkelsen J, Bradley DP, Subakan O, Silva MD, Liu R, Pickard M, Li Z, Tayber O, Li P, Hales P, Carsillo M, Neppalli VT, Berger AJ, Kupperman E, Manfredi M, Bolen JB, Van Ness B, Janz S) Clin Cancer Res 2011 Dec 01;17(23):7313-23 94 Citations |
| 1 | Primary vascularization of the graft determines the immunodominance of murine minor H antigens during organ transplantation. (Kwun J, Malarkannan S, Burlingham WJ, Knechtle SJ) J Immunol 2011 Oct 15;187(8):3997-4006 16 Citations |
| 1 | IRE1-dependent activation of AMPK in response to nitric oxide. (Meares GP, Hughes KJ, Naatz A, Papa FR, Urano F, Hansen PA, Benveniste EN, Corbett JA) Mol Cell Biol 2011 Nov;31(21):4286-97 70 Citations |
| 1 | Assessment of cone survival in response to CNTF, GDNF, and VEGF165b in a novel ex vivo model of end-stage retinitis pigmentosa. (Lipinski DM, Singh MS, MacLaren RE) Invest Ophthalmol Vis Sci 2011 Sep 21;52(10):7340-6 27 Citations |
| 2 | Cannabinoid receptor involvement in stress-induced cocaine reinstatement: potential interaction with noradrenergic pathways. (Vaughn LK, Mantsch JR, Vranjkovic O, Stroh G, Lacourt M, Kreutter M, Hillard CJ) Neuroscience 2012 Mar 01;204:117-24 37 Citations |
| 1 | Vav protein guanine nucleotide exchange factor regulates CD36 protein-mediated macrophage foam cell formation via calcium and dynamin-dependent processes. (Rahaman SO, Zhou G, Silverstein RL) J Biol Chem 2011 Oct 14;286(41):36011-36019 40 Citations |
| 1 | Prevention of GVHD while sparing GVL effect by targeting Th1 and Th17 transcription factor T-bet and RORγt in mice. (Yu Y, Wang D, Liu C, Kaosaard K, Semple K, Anasetti C, Yu XZ) Blood 2011 Nov 03;118(18):5011-20 138 Citations |
| 1 | A spontaneous mutation in Srebf2 leads to cataracts and persistent skin wounds in the lens opacity 13 (lop13) mouse. (Merath KM, Chang B, Dubielzig R, Jeannotte R, Sidjanin DJ) Mamm Genome 2011 Dec;22(11-12):661-73 11 Citations |
| 1 | Adenylate cyclase activity of Pseudomonas aeruginosa ExoY can mediate bleb-niche formation in epithelial cells and contributes to virulence. (Hritonenko V, Mun JJ, Tam C, Simon NC, Barbieri JT, Evans DJ, Fleiszig SM) Microb Pathog 2011 Nov;51(5):305-12 32 Citations |
| 1 | Subunit vaccine efficacy against Botulinum neurotoxin subtypes. (Henkel JS, Tepp WH, Przedpelski A, Fritz RB, Johnson EA, Barbieri JT) Vaccine 2011 Oct 13;29(44):7688-95 13 Citations |
| 1 | Immobilizing reporters for molecular imaging of the extracellular microenvironment in living animals. (Xia Z, Xing Y, Jeon J, Kim YP, Gall J, Dragulescu-Andrasi A, Gambhir SS, Rao J) ACS Chem Biol 2011 Oct 21;6(10):1117-26 18 Citations |
| 1 | Diapocynin and apocynin administration fails to significantly extend survival in G93A SOD1 ALS mice. (Trumbull KA, McAllister D, Gandelman MM, Fung WY, Lew T, Brennan L, Lopez N, Morré J, Kalyanaraman B, Beckman JS) Neurobiol Dis 2012 Jan;45(1):137-44 46 Citations |
| 1 | Evaluation of the first Ergocalciferol-derived, non hypercalcemic anti-cancer agent MT19c in ovarian cancer SKOV-3 cell lines. (Brard L, Lange TS, Robison K, Kim KK, Ara T, McCallum MM, Arnold LA, Moore RG, Singh RK) Gynecol Oncol 2011 Nov;123(2):370-8 14 Citations |
| 1 | Juvenile dermatomyositis: immunopathogenesis, role of myositis-specific autoantibodies, and review of rituximab use. (Chiu YE, Co DO) Pediatr Dermatol 2011;28(4):357-67 38 Citations |
| 1 | Efferent vagal nerve stimulation attenuates acute lung injury following burn: The importance of the gut-lung axis. (Krzyzaniak MJ, Peterson CY, Cheadle G, Loomis W, Wolf P, Kennedy V, Putnam JG, Bansal V, Eliceiri B, Baird A, Coimbra R) Surgery 2011 Sep;150(3):379-89 49 Citations |
| 1 | Constitutive androstane receptor activation decreases plasma apolipoprotein B-containing lipoproteins and atherosclerosis in low-density lipoprotein receptor-deficient mice. (Sberna AL, Assem M, Xiao R, Ayers S, Gautier T, Guiu B, Deckert V, Chevriaux A, Grober J, Le Guern N, Pais de Barros JP, Moore DD, Lagrost L, Masson D) Arterioscler Thromb Vasc Biol 2011 Oct;31(10):2232-9 32 Citations |
| 1 | Gelsolin-independent podosome formation in dendritic cells. (Hammarfjord O, Falet H, Gurniak C, Hartwig JH, Wallin RP) PLoS One 2011;6(7):e21615 10 Citations |
| 1 | CD103 deficiency prevents graft-versus-host disease but spares graft-versus-tumor effects mediated by alloreactive CD8 T cells. (Liu K, Anthony BA, Yearsly MM, Hamadani M, Gaughan A, Wang JJ, Devine SM, Hadley GA) PLoS One 2011;6(7):e21968 10 Citations |
| 1 | Using tandem mass spectrometry in targeted mode to identify activators of class IA PI3K in cancer. (Yang X, Turke AB, Qi J, Song Y, Rexer BN, Miller TW, Jänne PA, Arteaga CL, Cantley LC, Engelman JA, Asara JM) Cancer Res 2011 Sep 15;71(18):5965-75 14 Citations |
| 3 | Recruitment of prefrontal cortical endocannabinoid signaling by glucocorticoids contributes to termination of the stress response. (Hill MN, McLaughlin RJ, Pan B, Fitzgerald ML, Roberts CJ, Lee TT, Karatsoreos IN, Mackie K, Viau V, Pickel VM, McEwen BS, Liu QS, Gorzalka BB, Hillard CJ) J Neurosci 2011 Jul 20;31(29):10506-15 304 Citations |
| 1 | Transforming growth factor-beta-activated kinase 1 regulates natural killer cell-mediated cytotoxicity and cytokine production. (Rajasekaran K, Chu H, Kumar P, Xiao Y, Tinguely M, Samarakoon A, Kim TW, Li X, Thakar MS, Zhang J, Malarkannan S) J Biol Chem 2011 Sep 09;286(36):31213-24 29 Citations |
| 1 | Identifying nuclear phenotypes using semi-supervised metric learning. (Singh S, Janoos F, Pécot T, Caserta E, Leone G, Rittscher J, Machiraju R) Inf Process Med Imaging 2011;22:398-410 12 Citations |
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| 1 | Improvement of cardiac functions by chronic metformin treatment is associated with enhanced cardiac autophagy in diabetic OVE26 mice. (Xie Z, Lau K, Eby B, Lozano P, He C, Pennington B, Li H, Rathi S, Dong Y, Tian R, Kem D, Zou MH) Diabetes 2011 Jun;60(6):1770-8 446 Citations |
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| 1 | Strong CD28 costimulation suppresses induction of regulatory T cells from naive precursors through Lck signaling. (Semple K, Nguyen A, Yu Y, Wang H, Anasetti C, Yu XZ) Blood 2011 Mar 17;117(11):3096-103 77 Citations |
| 1 | Alternative strategies for gene therapy of hemophilia. (Montgomery RR, Shi Q) Hematology Am Soc Hematol Educ Program 2010;2010:197-202 5 Citations |
| 1 | Efficient and selective prevention of GVHD by antigen-specific induced Tregs via linked-suppression in mice. (Semple K, Yu Y, Wang D, Anasetti C, Yu XZ) Biol Blood Marrow Transplant 2011 Mar;17(3):309-18 43 Citations |
| 1 | Epigenetic silencing mediated through activated PI3K/AKT signaling in breast cancer. (Zuo T, Liu TM, Lan X, Weng YI, Shen R, Gu F, Huang YW, Liyanarachchi S, Deatherage DE, Hsu PY, Taslim C, Ramaswamy B, Shapiro CL, Lin HJ, Cheng AS, Jin VX, Huang TH) Cancer Res 2011 Mar 01;71(5):1752-62 53 Citations |
| 1 | Vav family Rho guanine nucleotide exchange factors regulate CD36-mediated macrophage foam cell formation. (Rahaman SO, Swat W, Febbraio M, Silverstein RL) J Biol Chem 2011 Mar 04;286(9):7010-7 40 Citations |
| 1 | Role of arachidonic acid lipoxygenase metabolites in acetylcholine-induced relaxations of mouse arteries. (Gauthier KM, Goldman DH, Aggarwal NT, Chawengsub Y, Falck JR, Campbell WB) Am J Physiol Heart Circ Physiol 2011 Mar;300(3):H725-35 33 Citations |
| 2 | Neuron- or glial-specific ablation of secreted renin does not affect renal renin, baseline arterial pressure, or metabolism. (Xu D, Borges GR, Davis DR, Agassandian K, Sequeira Lopez ML, Gomez RA, Cassell MD, Grobe JL, Sigmund CD) Physiol Genomics 2011 Mar 29;43(6):286-94 20 Citations |
| 2 | Cell proliferation in the absence of E2F1-3. (Wenzel PL, Chong JL, Sáenz-Robles MT, Ferrey A, Hagan JP, Gomez YM, Rajmohan R, Sharma N, Chen HZ, Pipas JM, Robinson ML, Leone G) Dev Biol 2011 Mar 01;351(1):35-45 59 Citations |
| 1 | Platelet-endothelial cell adhesion molecule-1 regulates endothelial NO synthase activity and localization through signal transducers and activators of transcription 3-dependent NOSTRIN expression. (McCormick ME, Goel R, Fulton D, Oess S, Newman D, Tzima E) Arterioscler Thromb Vasc Biol 2011 Mar;31(3):643-9 35 Citations |
| 1 | Effect of photobiomodulation on vinblastine-poisoned murine HERS cells. (Hodgson BD, Pyszka B, Henry MM, Buchmann E, Whelan HT) Photomed Laser Surg 2011 Apr;29(4):233-7 1 Citation |
| 1 | Isolation and culture of pulmonary endothelial cells from neonatal mice. (Sobczak M, Dargatz J, Chrzanowska-Wodnicka M) J Vis Exp 2010 Dec 14(46) 85 Citations |
| 1 | Genetic analysis of mouse strains with variable serum sodium concentrations identifies the Nalcn sodium channel as a novel player in osmoregulation. (Sinke AP, Caputo C, Tsaih SW, Yuan R, Ren D, Deen PM, Korstanje R) Physiol Genomics 2011 Mar 16;43(5):265-70 30 Citations |
| 1 | A functional family-wide screening of SP/KLF proteins identifies a subset of suppressors of KRAS-mediated cell growth. (Fernandez-Zapico ME, Lomberk GA, Tsuji S, DeMars CJ, Bardsley MR, Lin YH, Almada LL, Han JJ, Mukhopadhyay D, Ordog T, Buttar NS, Urrutia R) Biochem J 2011 Apr 15;435(2):529-37 84 Citations |
| 1 | Acamprosate reduces ethanol drinking behaviors and alters the metabolite profile in mice lacking ENT1. (Lee MR, Hinton DJ, Wu J, Mishra PK, Port JD, Macura SI, Choi DS) Neurosci Lett 2011 Feb 25;490(2):90-5 21 Citations |
| 2 | Abnormal fibrillin-1 expression and chronic oxidative stress mediate endothelial mesenchymal transition in a murine model of systemic sclerosis. (Xu H, Zaidi M, Struve J, Jones DW, Krolikowski JG, Nandedkar S, Lohr NL, Gadicherla A, Pagel PS, Csuka ME, Pritchard KA, Weihrauch D) Am J Physiol Cell Physiol 2011 Mar;300(3):C550-6 38 Citations |
| 1 | Operant sensation seeking requires metabotropic glutamate receptor 5 (mGluR5). (Olsen CM, Childs DS, Stanwood GD, Winder DG) PLoS One 2010 Nov 30;5(11):e15085 43 Citations |
| 1 | Constitutive androstane receptor activation stimulates faecal bile acid excretion and reverse cholesterol transport in mice. (Sberna AL, Assem M, Gautier T, Grober J, Guiu B, Jeannin A, Pais de Barros JP, Athias A, Lagrost L, Masson D) J Hepatol 2011 Jul;55(1):154-61 39 Citations |
| 1 | D-4F, an apoA-1 mimetic, decreases airway hyperresponsiveness, inflammation, and oxidative stress in a murine model of asthma. (Nandedkar SD, Weihrauch D, Xu H, Shi Y, Feroah T, Hutchins W, Rickaby DA, Duzgunes N, Hillery CA, Konduri KS, Pritchard KA Jr) J Lipid Res 2011 Mar;52(3):499-508 63 Citations |
| 2 | Are we putting too much stock in mice? (Auchampach JA, Maas JE, Wan TC, Figler RA, Gross GJ) J Mol Cell Cardiol 2011 Mar;50(3):584-5 |
| 1 | Refined mapping of the renal failure RF-3 quantitative trait locus. (O'Meara CC, Lazar J, Hoffman M, Moreno C, Jacob HJ) J Am Soc Nephrol 2011 Mar;22(3):518-25 7 Citations |
| 1 | Sustained activation of nuclear erythroid 2-related factor 2/antioxidant response element signaling promotes reductive stress in the human mutant protein aggregation cardiomyopathy in mice. (Rajasekaran NS, Varadharaj S, Khanderao GD, Davidson CJ, Kannan S, Firpo MA, Zweier JL, Benjamin IJ) Antioxid Redox Signal 2011 Mar 15;14(6):957-71 122 Citations |
| 1 | Mesenchymal stem cells facilitate axon sorting, myelination, and functional recovery in paralyzed mice deficient in Schwann cell-derived laminin. (Carlson KB, Singh P, Feaster MM, Ramnarain A, Pavlides C, Chen ZL, Yu WM, Feltri ML, Strickland S) Glia 2011 Feb;59(2):267-77 49 Citations |
| 1 | E2f1-3 are critical for myeloid development. (Trikha P, Sharma N, Opavsky R, Reyes A, Pena C, Ostrowski MC, Roussel MF, Leone G) J Biol Chem 2011 Feb 11;286(6):4783-95 31 Citations |
| 1 | Operant sensation seeking in the mouse. (Olsen CM, Winder DG) J Vis Exp 2010 Nov 10(45) 22 Citations |
| 2 | Mesenchymal stromal cells are present in the heart and promote growth of adult stem cells in vitro. (Lushaj EB, Anstadt E, Haworth R, Roenneburg D, Kim J, Hematti P, Kohmoto T) Cytotherapy 2011 Apr;13(4):400-6 23 Citations |
| 1 | Inactivation of Bardet-Biedl syndrome genes causes kidney defects. (Guo DF, Beyer AM, Yang B, Nishimura DY, Sheffield VC, Rahmouni K) Am J Physiol Renal Physiol 2011 Feb;300(2):F574-80 25 Citations |
| 1 | Tracking of multimodal therapeutic nanocomplexes targeting breast cancer in vivo. (Bardhan R, Chen W, Bartels M, Perez-Torres C, Botero MF, McAninch RW, Contreras A, Schiff R, Pautler RG, Halas NJ, Joshi A) Nano Lett 2010 Dec 08;10(12):4920-8 151 Citations |
| 1 | A CD36-dependent pathway enhances macrophage and adipose tissue inflammation and impairs insulin signalling. (Kennedy DJ, Kuchibhotla S, Westfall KM, Silverstein RL, Morton RE, Febbraio M) Cardiovasc Res 2011 Feb 15;89(3):604-13 162 Citations |
| 1 | Cytoskeletal mechanics of proplatelet maturation and platelet release. (Thon JN, Montalvo A, Patel-Hett S, Devine MT, Richardson JL, Ehrlicher A, Larson MK, Hoffmeister K, Hartwig JH, Italiano JE Jr) J Cell Biol 2010 Nov 15;191(4):861-74 240 Citations |
| 1 | The protective effect of overexpression of extracellular superoxide dismutase on nitric oxide bioavailability in the lung after exposure to hyperoxia stress. (Ahmed MN, Codipilly C, Hogg N, Auten RL) Exp Lung Res 2011 Feb;37(1):10-7 24 Citations |
| 1 | P-selectin-mediated platelet-neutrophil aggregate formation activates neutrophils in mouse and human sickle cell disease. (Polanowska-Grabowska R, Wallace K, Field JJ, Chen L, Marshall MA, Figler R, Gear AR, Linden J) Arterioscler Thromb Vasc Biol 2010 Dec;30(12):2392-9 148 Citations |
| 1 | Hexaminolevulinate-mediated photodynamic purging of marrow grafts with murine breast carcinoma. (Čunderlíková B, Vasovič V, Sieber F, Furre T, Borgen E, Nesland JM, Peng Q) Bone Marrow Transplant 2011 Aug;46(8):1118-27 13 Citations |
| 1 | Structural biology: On stress and pressure. (Sigmund CD) Nature 2010 Nov 04;468(7320):46-7 7 Citations |
| 1 | Increased ethanol consumption and preference in mice lacking neurotensin receptor type 2. (Lee MR, Hinton DJ, Unal SS, Richelson E, Choi DS) Alcohol Clin Exp Res 2011 Jan;35(1):99-107 28 Citations |
| 2 | The brain Renin-angiotensin system controls divergent efferent mechanisms to regulate fluid and energy balance. (Grobe JL, Grobe CL, Beltz TG, Westphal SG, Morgan DA, Xu D, de Lange WJ, Li H, Sakai K, Thedens DR, Cassis LA, Rahmouni K, Mark AL, Johnson AK, Sigmund CD) Cell Metab 2010 Nov 03;12(5):431-42 134 Citations |
| 1 | MS-275 sensitizes TRAIL-resistant breast cancer cells, inhibits angiogenesis and metastasis, and reverses epithelial-mesenchymal transition in vivo. (Srivastava RK, Kurzrock R, Shankar S) Mol Cancer Ther 2010 Dec;9(12):3254-66 116 Citations |
| 1 | Uncovering genes and regulatory pathways related to urinary albumin excretion. (Hageman RS, Leduc MS, Caputo CR, Tsaih SW, Churchill GA, Korstanje R) J Am Soc Nephrol 2011 Jan;22(1):73-81 11 Citations |
| 2 | Control of intestinal Nod2-mediated peptidoglycan recognition by epithelium-associated lymphocytes. (Duerr CU, Salzman NH, Dupont A, Szabo A, Normark BH, Normark S, Locksley RM, Mellroth P, Hornef MW) Mucosal Immunol 2011 May;4(3):325-34 26 Citations |
| 1 | RETRACTED: Differential effects of VEGFR-1 and VEGFR-2 inhibition on tumor metastases based on host organ environment. (Lee YJ, Karl DL, Maduekwe UN, Rothrock C, Ryeom S, D'Amore PA, Yoon SS) Cancer Res 2010 Nov 01;70(21):8357-67 54 Citations |
| 1 | CD36 participates in a signaling pathway that regulates ROS formation in murine VSMCs. (Li W, Febbraio M, Reddy SP, Yu DY, Yamamoto M, Silverstein RL) J Clin Invest 2010 Nov;120(11):3996-4006 121 Citations |
| 1 | Sustained delayed gastric emptying during repeated restraint stress in oxytocin knockout mice. (Babygirija R, Zheng J, Bülbül M, Cerjak D, Ludwig K, Takahashi T) J Neuroendocrinol 2010 Nov;22(11):1181-6 28 Citations |
| 1 | Targeted complement inhibitors protect against posttransplant cardiac ischemia and reperfusion injury and reveal an important role for the alternative pathway of complement activation. (Atkinson C, He S, Morris K, Qiao F, Casey S, Goddard M, Tomlinson S) J Immunol 2010 Dec 01;185(11):7007-13 52 Citations |
| 1 | Generation of iPSCs from mouse fibroblasts with a single gene, Oct4, and small molecules. (Li Y, Zhang Q, Yin X, Yang W, Du Y, Hou P, Ge J, Liu C, Zhang W, Zhang X, Wu Y, Li H, Liu K, Wu C, Song Z, Zhao Y, Shi Y, Deng H) Cell Res 2011 Jan;21(1):196-204 296 Citations |
| 1 | B-cell activating factor and v-Myc myelocytomatosis viral oncogene homolog (c-Myc) influence progression of chronic lymphocytic leukemia. (Zhang W, Kater AP, Widhopf GF 2nd, Chuang HY, Enzler T, James DF, Poustovoitov M, Tseng PH, Janz S, Hoh C, Herschman H, Karin M, Kipps TJ) Proc Natl Acad Sci U S A 2010 Nov 02;107(44):18956-60 60 Citations |
| 1 | A novel approach for the generation of genetically modified mammary epithelial cell cultures yields new insights into TGFβ signaling in the mammary gland. (Kohn EA, Du Z, Sato M, Van Schyndle CM, Welsh MA, Yang YA, Stuelten CH, Tang B, Ju W, Bottinger EP, Wakefield LM) Breast Cancer Res 2010;12(5):R83 22 Citations |
| 1 | Filamin A regulates focal adhesion disassembly and suppresses breast cancer cell migration and invasion. (Xu Y, Bismar TA, Su J, Xu B, Kristiansen G, Varga Z, Teng L, Ingber DE, Mammoto A, Kumar R, Alaoui-Jamali MA) J Exp Med 2010 Oct 25;207(11):2421-37 143 Citations |
| 1 | Elastic laminae in vascular development and disease. (Liu SQ, Teft BJ, Zhang LQ, Li YC, Wu YH) Mol Cell Biomech 2010 Jun;7(2):59-76 5 Citations |
| 1 | Therapeutic targeting of C-terminal binding protein in human cancer. (Straza MW, Paliwal S, Kovi RC, Rajeshkumar B, Trenh P, Parker D, Whalen GF, Lyle S, Schiffer CA, Grossman SR) Cell Cycle 2010 Sep 15;9(18):3740-50 56 Citations |
| 1 | Recommended nomenclature for five mammalian carboxylesterase gene families: human, mouse, and rat genes and proteins. (Holmes RS, Wright MW, Laulederkind SJ, Cox LA, Hosokawa M, Imai T, Ishibashi S, Lehner R, Miyazaki M, Perkins EJ, Potter PM, Redinbo MR, Robert J, Satoh T, Yamashita T, Yan B, Yokoi T, Zechner R, Maltais LJ) Mamm Genome 2010 Oct;21(9-10):427-41 160 Citations |
| 1 | Dynamic Lkb1-TORC1 signaling as a possible mechanism for regulating the endoderm-intestine transition. (Marshall KE, Tomasini AJ, Makky K, N Kumar S, Mayer AN) Dev Dyn 2010 Nov;239(11):3000-12 9 Citations |
| 1 | Mesenchymal stromal cells expressing ErbB-2/neu elicit protective antibreast tumor immunity in vivo, which is paradoxically suppressed by IFN-gamma and tumor necrosis factor-alpha priming. (Romieu-Mourez R, François M, Abate A, Boivin MN, Birman E, Bailey D, Bramson JL, Forner K, Young YK, Medin JA, Galipeau J) Cancer Res 2010 Oct 15;70(20):7742-7 16 Citations |
| 1 | A feedback loop regulates splicing of the spinal muscular atrophy-modifying gene, SMN2. (Jodelka FM, Ebert AD, Duelli DM, Hastings ML) Hum Mol Genet 2010 Dec 15;19(24):4906-17 75 Citations |
| 1 | CXCL12 chemokine expression and secretion regulates colorectal carcinoma cell anoikis through Bim-mediated intrinsic apoptosis. (Drury LJ, Wendt MK, Dwinell MB) PLoS One 2010 Sep 22;5(9):e12895 40 Citations |
| 1 | Disruption of bone development and homeostasis by trisomy in Ts65Dn Down syndrome mice. (Blazek JD, Gaddy A, Meyer R, Roper RJ, Li J) Bone 2011 Feb;48(2):275-80 33 Citations |
| 2 | Gene targeting in the rat: advances and opportunities. (Jacob HJ, Lazar J, Dwinell MR, Moreno C, Geurts AM) Trends Genet 2010 Dec;26(12):510-8 91 Citations |
| 1 | Selective degradation of aggregate-prone CryAB mutants by HSPB1 is mediated by ubiquitin-proteasome pathways. (Zhang H, Rajasekaran NS, Orosz A, Xiao X, Rechsteiner M, Benjamin IJ) J Mol Cell Cardiol 2010 Dec;49(6):918-30 45 Citations |
| 1 | Leptospira as an emerging pathogen: a review of its biology, pathogenesis and host immune responses. (Evangelista KV, Coburn J) Future Microbiol 2010 Sep;5(9):1413-25 280 Citations |
| 1 | Fast, reproducible measurement of the vascular input function in mice using constrained reconstruction and cardiac sampling. (Ragan DK, Lai SY, Bankson JA) NMR Biomed 2011 May;24(4):373-84 10 Citations |
| 1 | Vascular endothelial function and hypertension: insights and directions. (Dharmashankar K, Widlansky ME) Curr Hypertens Rep 2010 Dec;12(6):448-55 359 Citations |
| 1 | Hypobaric hypoxia exacerbates the neuroinflammatory response to traumatic brain injury. (Goodman MD, Makley AT, Huber NL, Clarke CN, Friend LA, Schuster RM, Bailey SR, Barnes SL, Dorlac WC, Johannigman JA, Lentsch AB, Pritts TA) J Surg Res 2011 Jan;165(1):30-7 52 Citations |
| 1 | Contrasting vascular effects caused by loss of Bardet-Biedl syndrome genes. (Beyer AM, Guo DF, Sheffield VC, Rahmouni K) Am J Physiol Heart Circ Physiol 2010 Dec;299(6):H1902-7 13 Citations |
| 1 | Promoter-specific lentivectors for long-term, cardiac-directed therapy of Fabry disease. (Lee CJ, Fan X, Guo X, Medin JA) J Cardiol 2011 Jan;57(1):115-22 33 Citations |
| 1 | Mucin gene expression and mouse middle ear epithelium. (Kerschner JE, Li J, Tsushiya K, Khampang P) Int J Pediatr Otorhinolaryngol 2010 Aug;74(8):864-8 14 Citations |
| 2 | Pancreatic stellate cell models for transcriptional studies of desmoplasia-associated genes. (Mathison A, Liebl A, Bharucha J, Mukhopadhyay D, Lomberk G, Shah V, Urrutia R) Pancreatology 2010;10(4):505-16 |
| 1 | Differential roles of Sall4 isoforms in embryonic stem cell pluripotency. (Rao S, Zhen S, Roumiantsev S, McDonald LT, Yuan GC, Orkin SH) Mol Cell Biol 2010 Nov;30(22):5364-80 154 Citations |
| 1 | Sequence variation at multiple loci influences red cell hemoglobin concentration. (Peters LL, Shavit JA, Lambert AJ, Tsaih SW, Li Q, Su Z, Leduc MS, Paigen B, Churchill GA, Ginsburg D, Brugnara C) Blood 2010 Dec 16;116(25):e139-49 10 Citations |
| 1 | Myocardial regeneration potential of adipose tissue-derived stem cells. (Bai X, Alt E) Biochem Biophys Res Commun 2010 Oct 22;401(3):321-6 67 Citations |
| 1 | Apolipoprotein A-I modulates regulatory T cells in autoimmune LDLr-/-, ApoA-I-/- mice. (Wilhelm AJ, Zabalawi M, Owen JS, Shah D, Grayson JM, Major AS, Bhat S, Gibbs DP Jr, Thomas MJ, Sorci-Thomas MG) J Biol Chem 2010 Nov 12;285(46):36158-69 110 Citations |
| 4 | Endothelial microparticles induce inflammation in acute lung injury. (Buesing KL, Densmore JC, Kaul S, Pritchard KA Jr, Jarzembowski JA, Gourlay DM, Oldham KT) J Surg Res 2011 Mar;166(1):32-9 80 Citations |
| 2 | Neuroprotection by a mitochondria-targeted drug in a Parkinson's disease model. (Ghosh A, Chandran K, Kalivendi SV, Joseph J, Antholine WE, Hillard CJ, Kanthasamy A, Kanthasamy A, Kalyanaraman B) Free Radic Biol Med 2010 Dec 01;49(11):1674-84 171 Citations |
| 1 | Prevention of diabetic nephropathy in Ins2(+/)⁻(AkitaJ) mice by the mitochondria-targeted therapy MitoQ. (Chacko BK, Reily C, Srivastava A, Johnson MS, Ye Y, Ulasova E, Agarwal A, Zinn KR, Murphy MP, Kalyanaraman B, Darley-Usmar V) Biochem J 2010 Nov 15;432(1):9-19 199 Citations |
| 2 | Cardiovascular consequences of genetic variation at -6/235 in human angiotensinogen using "humanized" gene-targeted mice. (Grobe JL, Dickson ME, Park S, Davis DR, Born EJ, Sigmund CD) Hypertension 2010 Nov;56(5):981-7 9 Citations |
| 1 | Comparison of unrestrained plethysmography and forced oscillation for identifying genetic variability of airway responsiveness in inbred mice. (Berndt A, Leme AS, Williams LK, Von Smith R, Savage HS, Stearns TM, Tsaih SW, Shapiro SD, Peters LL, Paigen B, Svenson KL) Physiol Genomics 2011 Jan 07;43(1):1-11 31 Citations |
| 1 | A new pyrimidine-specific reporter gene: a mutated human deoxycytidine kinase suitable for PET during treatment with acycloguanosine-based cytotoxic drugs. (Likar Y, Zurita J, Dobrenkov K, Shenker L, Cai S, Neschadim A, Medin JA, Sadelain M, Hricak H, Ponomarev V) J Nucl Med 2010 Sep;51(9):1395-403 58 Citations |
| 1 | TRPA1 mediates mechanical currents in the plasma membrane of mouse sensory neurons. (Vilceanu D, Stucky CL) PLoS One 2010 Aug 16;5(8):e12177 120 Citations |
| 2 | Evidence that the acute phase of ischemic preconditioning does not require signaling by the A 2B adenosine receptor. (Maas JE, Wan TC, Figler RA, Gross GJ, Auchampach JA) J Mol Cell Cardiol 2010 Nov;49(5):886-93 31 Citations |
| 1 | Identification of genetic determinants of IGF-1 levels and longevity among mouse inbred strains. (Leduc MS, Hageman RS, Meng Q, Verdugo RA, Tsaih SW, Churchill GA, Paigen B, Yuan R) Aging Cell 2010 Oct;9(5):823-36 32 Citations |
| 1 | High levels of expression of human stromal cell-derived factor-1 are associated with worse prognosis in patients with stage II pancreatic ductal adenocarcinoma. (Liang JJ, Zhu S, Bruggeman R, Zaino RJ, Evans DB, Fleming JB, Gomez HF, Zander DS, Wang H) Cancer Epidemiol Biomarkers Prev 2010 Oct;19(10):2598-604 59 Citations |
| 3 | Rap1b facilitates NK cell functions via IQGAP1-mediated signalosomes. (Awasthi A, Samarakoon A, Chu H, Kamalakannan R, Quilliam LA, Chrzanowska-Wodnicka M, White GC 2nd, Malarkannan S) J Exp Med 2010 Aug 30;207(9):1923-38 48 Citations |
| 1 | Tracking long-term survival of intramyocardially delivered human adipose tissue-derived stem cells using bioluminescence imaging. (Bai X, Yan Y, Coleman M, Wu G, Rabinovich B, Seidensticker M, Alt E) Mol Imaging Biol 2011 Aug;13(4):633-45 57 Citations |
| 1 | Chronic monoacylglycerol lipase blockade causes functional antagonism of the endocannabinoid system. (Schlosburg JE, Blankman JL, Long JZ, Nomura DK, Pan B, Kinsey SG, Nguyen PT, Ramesh D, Booker L, Burston JJ, Thomas EA, Selley DE, Sim-Selley LJ, Liu QS, Lichtman AH, Cravatt BF) Nat Neurosci 2010 Sep;13(9):1113-9 541 Citations |
| 2 | Novel clearance mechanisms of platelets. (Grozovsky R, Hoffmeister KM, Falet H) Curr Opin Hematol 2010 Nov;17(6):585-9 98 Citations |
| 2 | Platelet endothelial cell adhesion molecule-1 regulates collagen-stimulated platelet function by modulating the association of phosphatidylinositol 3-kinase with Grb-2-associated binding protein-1 and linker for activation of T cells. (Moraes LA, Barrett NE, Jones CI, Holbrook LM, Spyridon M, Sage T, Newman DK, Gibbins JM) J Thromb Haemost 2010 Nov;8(11):2530-41 41 Citations |
| 1 | Tumor antigen analysis in neuroblastoma by serological interrogation of bioinformatic data. (Kohler ME, Johnson BD, Palen K, Chen QR, Khan J, Orentas RJ) Cancer Sci 2010 Nov;101(11):2316-24 6 Citations |
| 1 | A novel interaction between FlnA and Syk regulates platelet ITAM-mediated receptor signaling and function. (Falet H, Pollitt AY, Begonja AJ, Weber SE, Duerschmied D, Wagner DD, Watson SP, Hartwig JH) J Exp Med 2010 Aug 30;207(9):1967-79 105 Citations |
| 1 | Activated protein C targets CD8+ dendritic cells to reduce the mortality of endotoxemia in mice. (Kerschen E, Hernandez I, Zogg M, Jia S, Hessner MJ, Fernandez JA, Griffin JH, Huettner CS, Castellino FJ, Weiler H) J Clin Invest 2010 Sep;120(9):3167-78 84 Citations |
| 1 | Vagal nerve stimulation protects against burn-induced intestinal injury through activation of enteric glia cells. (Costantini TW, Bansal V, Krzyzaniak M, Putnam JG, Peterson CY, Loomis WH, Wolf P, Baird A, Eliceiri BP, Coimbra R) Am J Physiol Gastrointest Liver Physiol 2010 Dec;299(6):G1308-18 135 Citations |
| 1 | Mechanisms of cell signaling by the scavenger receptor CD36: implications in atherosclerosis and thrombosis. (Silverstein RL, Li W, Park YM, Rahaman SO) Trans Am Clin Climatol Assoc 2010;121:206-20 152 Citations |
| 1 | Portal vein ligation accelerates tumor growth in ligated, but not contralateral lobes. (Sakai N, Clarke CN, Schuster R, Blanchard J, Tevar AD, Edwards MJ, Lentsch AB) World J Gastroenterol 2010 Aug 14;16(30):3816-26 11 Citations |
| 2 | Effect of Borrelia burgdorferi OspC at the site of inoculation in mouse skin. (Antonara S, Ristow L, McCarthy J, Coburn J) Infect Immun 2010 Nov;78(11):4723-33 28 Citations |
| 1 | Early expression of stem cell-associated genes within the CD8 compartment after treatment with a tumor vaccine. (Kohler ME, Hallett WH, Chen QR, Khan J, Johnson BD, Orentas RJ) Cell Immunol 2010;265(1):65-73 4 Citations |
| 1 | Cutting edge: mutation of Francisella tularensis mviN leads to increased macrophage absent in melanoma 2 inflammasome activation and a loss of virulence. (Ulland TK, Buchan BW, Ketterer MR, Fernandes-Alnemri T, Meyerholz DK, Apicella MA, Alnemri ES, Jones BD, Nauseef WM, Sutterwala FS) J Immunol 2010 Sep 01;185(5):2670-4 69 Citations |
| 1 | Induction and rescue of Nod2-dependent Th1-driven granulomatous inflammation of the ileum. (Biswas A, Liu YJ, Hao L, Mizoguchi A, Salzman NH, Bevins CL, Kobayashi KS) Proc Natl Acad Sci U S A 2010 Aug 17;107(33):14739-44 145 Citations |
| 1 | Neuropilin-1 mediates divergent R-Smad signaling and the myofibroblast phenotype. (Cao Y, Szabolcs A, Dutta SK, Yaqoob U, Jagavelu K, Wang L, Leof EB, Urrutia RA, Shah VH, Mukhopadhyay D) J Biol Chem 2010 Oct 08;285(41):31840-8 77 Citations |
| 3 | Deficiency in endocannabinoid signaling in the nucleus accumbens induced by chronic unpredictable stress. (Wang W, Sun D, Pan B, Roberts CJ, Sun X, Hillard CJ, Liu QS) Neuropsychopharmacology 2010 Oct;35(11):2249-61 99 Citations |
| 1 | Effect of the data sampling rate on accuracy of indices for heart rate and blood pressure variability and baroreflex function in resting rats and mice. (Bhatia V, Rarick KR, Stauss HM) Physiol Meas 2010 Sep;31(9):1185-201 25 Citations |
| 1 | α-enolase autoantibodies cross-reactive to viral proteins in a mouse model of biliary atresia. (Lu BR, Brindley SM, Tucker RM, Lambert CL, Mack CL) Gastroenterology 2010 Nov;139(5):1753-61 74 Citations |
| 2 | Sterol carrier protein-2 (SCP-2) involvement in cholesterol hydroperoxide cytotoxicity as revealed by SCP-2 inhibitor effects. (Kriska T, Pilat A, Schmitt JC, Girotti AW) J Lipid Res 2010 Nov;51(11):3174-84 23 Citations |
| 1 | Cabin1 expression suggests roles in neuronal development. (Hammond DR, Udvadia AJ) Dev Dyn 2010 Sep;239(9):2443-51 20 Citations |
| 1 | Diagnosis of partial body radiation exposure in mice using peripheral blood gene expression profiles. (Meadows SK, Dressman HK, Daher P, Himburg H, Russell JL, Doan P, Chao NJ, Lucas J, Nevins JR, Chute JP) PLoS One 2010 Jul 12;5(7):e11535 50 Citations |
| 1 | Early differential expression of oncostatin M in obstructive nephropathy. (Elbjeirami WM, Truong LD, Tawil A, Wang W, Dawson S, Lan HY, Zhang P, Garcia GE, Wayne Smith C) J Interferon Cytokine Res 2010 Jul;30(7):513-23 16 Citations |
| 1 | NADPH oxidase 2 mediates intermittent hypoxia-induced mitochondrial complex I inhibition: relevance to blood pressure changes in rats. (Khan SA, Nanduri J, Yuan G, Kinsman B, Kumar GK, Joseph J, Kalyanaraman B, Prabhakar NR) Antioxid Redox Signal 2011 Feb 15;14(4):533-42 70 Citations |
| 1 | Identification, characterization and immunogenicity of an O-antigen capsular polysaccharide of Francisella tularensis. (Apicella MA, Post DM, Fowler AC, Jones BD, Rasmussen JA, Hunt JR, Imagawa S, Choudhury B, Inzana TJ, Maier TM, Frank DW, Zahrt TC, Chaloner K, Jennings MP, McLendon MK, Gibson BW) PLoS One 2010 Jul 06;5(7):e11060 78 Citations |
| 1 | Kitlow stem cells cause resistance to Kit/platelet-derived growth factor alpha inhibitors in murine gastrointestinal stromal tumors. (Bardsley MR, Horváth VJ, Asuzu DT, Lorincz A, Redelman D, Hayashi Y, Popko LN, Young DL, Lomberk GA, Urrutia RA, Farrugia G, Rubin BP, Ordog T) Gastroenterology 2010 Sep;139(3):942-52 101 Citations |
| 1 | Phosphomimetic mutants of pigment epithelium-derived factor with enhanced antiangiogenic activity as potent anticancer agents. (Konson A, Pradeep S, Seger R) Cancer Res 2010 Aug 01;70(15):6247-57 33 Citations |
| 1 | Activation of paternally expressed genes and perinatal death caused by deletion of the Gtl2 gene. (Zhou Y, Cheunsuchon P, Nakayama Y, Lawlor MW, Zhong Y, Rice KA, Zhang L, Zhang X, Gordon FE, Lidov HG, Bronson RT, Klibanski A) Development 2010 Aug;137(16):2643-52 129 Citations |
| 1 | Involvement of noradrenergic neurotransmission in the stress- but not cocaine-induced reinstatement of extinguished cocaine-induced conditioned place preference in mice: role for β-2 adrenergic receptors. (Mantsch JR, Weyer A, Vranjkovic O, Beyer CE, Baker DA, Caretta H) Neuropsychopharmacology 2010 Oct;35(11):2165-78 103 Citations |
| 1 | Targeting FVIII expression to endothelial cells regenerates a releasable pool of FVIII and restores hemostasis in a mouse model of hemophilia A. (Shi Q, Fahs SA, Kuether EL, Cooley BC, Weiler H, Montgomery RR) Blood 2010 Oct 21;116(16):3049-57 42 Citations |
| 1 | Extending the chinchilla middle ear epithelial model for mucin gene investigation. (Kerschner JE, Khampang P, Samuels T) Int J Pediatr Otorhinolaryngol 2010 Sep;74(9):980-5 10 Citations |
| 2 | The Ras oncogene signals centrosome amplification in mammary epithelial cells through cyclin D1/Cdk4 and Nek2. (Zeng X, Shaikh FY, Harrison MK, Adon AM, Trimboli AJ, Carroll KA, Sharma N, Timmers C, Chodosh LA, Leone G, Saavedra HI) Oncogene 2010 Sep 09;29(36):5103-12 73 Citations |
| 1 | Reconstituting organ-level lung functions on a chip. (Huh D, Matthews BD, Mammoto A, Montoya-Zavala M, Hsin HY, Ingber DE) Science 2010 Jun 25;328(5986):1662-8 3350 Citations |
| 1 | Reduced effect of NMDA glutamate receptor antagonist on ethanol-induced ataxia and striatal glutamate levels in mice lacking ENT1. (Nam HW, Lee MR, Hinton DJ, Choi DS) Neurosci Lett 2010 Aug 02;479(3):277-81 16 Citations |
| 1 | Bradykinin decreases podocyte permeability through ADAM17-dependent epidermal growth factor receptor activation and zonula occludens-1 rearrangement. (Dey M, Baldys A, Sumter DB, Göoz P, Luttrell LM, Raymond JR, Göoz M) J Pharmacol Exp Ther 2010 Sep 01;334(3):775-83 32 Citations |
| 1 | Surviving lethal septic shock without fluid resuscitation in a rodent model. (Li Y, Liu B, Fukudome EY, Kochanek AR, Finkelstein RA, Chong W, Jin G, Lu J, deMoya MA, Velmahos GC, Alam HB) Surgery 2010 Aug;148(2):246-54 56 Citations |
| 1 | Deficiency of telomerase activity aggravates the blood-brain barrier disruption and neuroinflammatory responses in a model of experimental stroke. (Zhang B, Chen L, Swartz KR, Bruemmer D, Eum SY, Huang W, Seelbach M, Choi YJ, Hennig B, Toborek M) J Neurosci Res 2010 Oct;88(13):2859-68 32 Citations |
| 1 | Conserved gammaherpesvirus kinase and histone variant H2AX facilitate gammaherpesvirus latency in vivo. (Tarakanova VL, Stanitsa E, Leonardo SM, Bigley TM, Gauld SB) Virology 2010 Sep 15;405(1):50-61 38 Citations |
| 1 | Efferent vagal nerve stimulation attenuates gut barrier injury after burn: modulation of intestinal occludin expression. (Costantini TW, Bansal V, Peterson CY, Loomis WH, Putnam JG, Rankin F, Wolf P, Eliceiri BP, Baird A, Coimbra R) J Trauma 2010 Jun;68(6):1349-54; discussion 1354-6 76 Citations |
| 1 | Rostrocaudal analysis of corpus callosum demyelination and axon damage across disease stages refines diffusion tensor imaging correlations with pathological features. (Xie M, Tobin JE, Budde MD, Chen CI, Trinkaus K, Cross AH, McDaniel DP, Song SK, Armstrong RC) J Neuropathol Exp Neurol 2010 Jul;69(7):704-16 142 Citations |
| 1 | In vivo studies of mutant fibrillin-1 microfibrils. (Charbonneau NL, Carlson EJ, Tufa S, Sengle G, Manalo EC, Carlberg VM, Ramirez F, Keene DR, Sakai LY) J Biol Chem 2010 Aug 06;285(32):24943-55 82 Citations |
| 1 | Salirasib in the treatment of pancreatic cancer. (Bustinza-Linares E, Kurzrock R, Tsimberidou AM) Future Oncol 2010 Jun;6(6):885-91 45 Citations |
| 1 | Anaplastic plasmacytoma of mouse--establishing parallels between subtypes of mouse and human plasma cell neoplasia. (de Jong D, Janz S) J Pathol 2010 Jul;221(3):242-7 2 Citations |
| 1 | Analyzing complex traits with congenic strains. (Shao H, Sinasac DS, Burrage LC, Hodges CA, Supelak PJ, Palmert MR, Moreno C, Cowley AW Jr, Jacob HJ, Nadeau JH) Mamm Genome 2010 Jun;21(5-6):276-86 41 Citations |
| 1 | First evidence of Okadaic acid acyl-derivative and Dinophysistoxin-3 in mussel samples collected in Chiloe Island, Southern Chile. (García C, Pruzzo M, Rodríguez-Unda N, Contreras C, Lagos N) J Toxicol Sci 2010 Jun;35(3):335-44 21 Citations |
| 1 | Site mapping and characterization of O-glycan structures on alpha-dystroglycan isolated from rabbit skeletal muscle. (Stalnaker SH, Hashmi S, Lim JM, Aoki K, Porterfield M, Gutierrez-Sanchez G, Wheeler J, Ervasti JM, Bergmann C, Tiemeyer M, Wells L) J Biol Chem 2010 Aug 06;285(32):24882-91 84 Citations |
| 1 | Src family kinases participate in the regulation of encephalomyocarditis virus-induced cyclooxygenase-2 expression by macrophages. (Freudenburg W, Buller RM, Corbett JA) J Gen Virol 2010 Sep;91(Pt 9):2278-85 10 Citations |
| 3 | Genetic deletion of apolipoprotein A-I increases airway hyperresponsiveness, inflammation, and collagen deposition in the lung. (Wang W, Xu H, Shi Y, Nandedkar S, Zhang H, Gao H, Feroah T, Weihrauch D, Schulte ML, Jones DW, Jarzembowski J, Sorci-Thomas M, Pritchard KA Jr) J Lipid Res 2010 Sep;51(9):2560-70 71 Citations |
| 1 | Thrombospondin-1 regulates the normal prostate in vivo through angiogenesis and TGF-beta activation. (Fitchev PP, Wcislak SM, Lee C, Bergh A, Brendler CB, Stellmach VM, Crawford SE, Mavroudis CD, Cornwell ML, Doll JA) Lab Invest 2010 Jul;90(7):1078-90 22 Citations |
| 1 | Genetic reporter system for oncogenic Igh-Myc translocations in mice. (Takizawa M, Kim JS, Tessarollo L, McNeil N, Waldschmidt TJ, Casellas R, Ried T, Janz S) Oncogene 2010 Jul 15;29(28):4113-20 2 Citations |
| 1 | Alpha-galactosidase A-Tat fusion enhances storage reduction in hearts and kidneys of Fabry mice. (Higuchi K, Yoshimitsu M, Fan X, Guo X, Rasaiah VI, Yen J, Tei C, Takenaka T, Medin JA) Mol Med 2010;16(5-6):216-21 13 Citations |
| 1 | Factor IX ectopically expressed in platelets can be stored in alpha-granules and corrects the phenotype of hemophilia B mice. (Zhang G, Shi Q, Fahs SA, Kuether EL, Walsh CE, Montgomery RR) Blood 2010 Aug 26;116(8):1235-43 46 Citations |
| 1 | Involvement of reductive stress in the cardiomyopathy in transgenic mice with cardiac-specific overexpression of heat shock protein 27. (Zhang X, Min X, Li C, Benjamin IJ, Qian B, Zhang X, Ding Z, Gao X, Yao Y, Ma Y, Cheng Y, Liu L) Hypertension 2010 Jun;55(6):1412-7 100 Citations |
| 1 | NF-kappaB/STAT3/PI3K signaling crosstalk in iMyc E mu B lymphoma. (Han SS, Yun H, Son DJ, Tompkins VS, Peng L, Chung ST, Kim JS, Park ES, Janz S) Mol Cancer 2010 Apr 30;9:97 100 Citations |
| 1 | Folate regulation of axonal regeneration in the rodent central nervous system through DNA methylation. (Iskandar BJ, Rizk E, Meier B, Hariharan N, Bottiglieri T, Finnell RH, Jarrard DF, Banerjee RV, Skene JH, Nelson A, Patel N, Gherasim C, Simon K, Cook TD, Hogan KJ) J Clin Invest 2010 May;120(5):1603-16 136 Citations |
| 1 | Mouse models for the study of autoimmune type 1 diabetes: a NOD to similarities and differences to human disease. (Driver JP, Serreze DV, Chen YG) Semin Immunopathol 2011 Jan;33(1):67-87 149 Citations |
| 1 | Mitochondrial metabolism and ROS generation are essential for Kras-mediated tumorigenicity. (Weinberg F, Hamanaka R, Wheaton WW, Weinberg S, Joseph J, Lopez M, Kalyanaraman B, Mutlu GM, Budinger GR, Chandel NS) Proc Natl Acad Sci U S A 2010 May 11;107(19):8788-93 1435 Citations |
| 1 | Corneal myofibroblast generation from bone marrow-derived cells. (Barbosa FL, Chaurasia SS, Cutler A, Asosingh K, Kaur H, de Medeiros FW, Agrawal V, Wilson SE) Exp Eye Res 2010 Jul;91(1):92-6 97 Citations |
| 2 | Cardiac myocyte-specific overexpression of human GTP cyclohydrolase I protects against acute cardiac allograft rejection. (Ionova IA, Vásquez-Vivar J, Cooley BC, Khanna AK, Whitsett J, Herrnreiter A, Migrino RQ, Ge ZD, Regner KR, Channon KM, Alp NJ, Pieper GM) Am J Physiol Heart Circ Physiol 2010 Jul;299(1):H88-96 8 Citations |
| 2 | Integrin-independent role of CalDAG-GEFI in neutrophil chemotaxis. (Carbo C, Duerschmied D, Goerge T, Hattori H, Sakai J, Cifuni SM, White GC 2nd, Chrzanowska-Wodnicka M, Luo HR, Wagner DD) J Leukoc Biol 2010 Aug;88(2):313-9 28 Citations |
| 1 | Epidermal neural crest stem cell (EPI-NCSC)--mediated recovery of sensory function in a mouse model of spinal cord injury. (Hu YF, Gourab K, Wells C, Clewes O, Schmit BD, Sieber-Blum M) Stem Cell Rev Rep 2010 Jun;6(2):186-98 73 Citations |
| 1 | Surprising inability of singlet oxygen-generated 6-hydroperoxycholesterol to induce damaging free radical lipid peroxidation in cell membranes. (Korytowski W, Schmitt JC, Girotti AW) Photochem Photobiol 2010;86(4):747-51 20 Citations |
| 1 | Trans-synaptic EphB2-ephrin-B3 interaction regulates excitatory synapse density by inhibition of postsynaptic MAPK signaling. (McClelland AC, Hruska M, Coenen AJ, Henkemeyer M, Dalva MB) Proc Natl Acad Sci U S A 2010 May 11;107(19):8830-5 59 Citations |
| 1 | Growth suppression of mouse pituitary corticotroph tumor AtT20 cells by curcumin: a model for treating Cushing's disease. (Bangaru ML, Woodliff J, Raff H, Kansra S) PLoS One 2010 Apr 13;5(4):e9893 18 Citations |
| 2 | PECAM-1 functions as a negative regulator of laminin-induced platelet activation. (Crockett J, Newman DK, Newman PJ) J Thromb Haemost 2010 Jul;8(7):1584-93 17 Citations |
| 2 | TCR stimulation drives cleavage and shedding of the ITIM receptor CD31. (Fornasa G, Groyer E, Clement M, Dimitrov J, Compain C, Gaston AT, Varthaman A, Khallou-Laschet J, Newman DK, Graff-Dubois S, Nicoletti A, Caligiuri G) J Immunol 2010 May 15;184(10):5485-92 54 Citations |
| 1 | Role of mitochondrial reactive oxygen species in osteoclast differentiation. (Srinivasan S, Koenigstein A, Joseph J, Sun L, Kalyanaraman B, Zaidi M, Avadhani NG) Ann N Y Acad Sci 2010 Mar;1192(1):245-52 108 Citations |
| 1 | Ectopic expression of wild-type FGFR3 cooperates with MYC to accelerate development of B-cell lineage neoplasms. (Zingone A, Cultraro CM, Shin DM, Bean CM, Morse HC 3rd, Janz S, Kuehl WM) Leukemia 2010 Jun;24(6):1171-8 21 Citations |
| 1 | Bradykinin B2 receptor interacts with integrin alpha5beta1 to transactivate epidermal growth factor receptor in kidney cells. (Kramarenko II, Bunni MA, Raymond JR, Garnovskaya MN) Mol Pharmacol 2010 Jul;78(1):126-34 17 Citations |
| 2 | Blockade of interleukin-23 signaling results in targeted protection of the colon and allows for separation of graft-versus-host and graft-versus-leukemia responses. (Das R, Komorowski R, Hessner MJ, Subramanian H, Huettner CS, Cua D, Drobyski WR) Blood 2010 Jun 24;115(25):5249-58 46 Citations |
| 1 | Exogenous stem cell factor improves interstitial cells of Cajal restoration after blockade of c-kit signaling pathway. (Tong W, Jia H, Zhang L, Li C, Ridolfi TJ, Liu B) Scand J Gastroenterol 2010 Aug;45(7-8):844-51 32 Citations |
| 1 | Colonic inflammation alters Src kinase-dependent gating properties of single Ca2+ channels via tyrosine nitration. (Ross GR, Kang M, Akbarali HI) Am J Physiol Gastrointest Liver Physiol 2010 Jun;298(6):G976-84 14 Citations |
| 1 | Toll-like receptor-4 mediates intestinal barrier breakdown after thermal injury. (Peterson CY, Costantini TW, Loomis WH, Putnam JG, Wolf P, Bansal V, Eliceiri BP, Baird A, Coimbra R) Surg Infect (Larchmt) 2010 Apr;11(2):137-44 46 Citations |
| 1 | ENT1 regulates ethanol-sensitive EAAT2 expression and function in astrocytes. (Wu J, Lee MR, Choi S, Kim T, Choi DS) Alcohol Clin Exp Res 2010 Jun;34(6):1110-7 41 Citations |
| 1 | Phosphatidylinositol 3-kinase regulates macrophage responses to double-stranded RNA and encephalomyocarditis virus. (Freudenburg W, Moran JM, Lents NH, Baldassare JJ, Buller RM, Corbett JA) J Innate Immun 2010;2(1):77-86 14 Citations |
| 1 | Human recombinant vascular endothelial growth factor reduces necrosis and enhances hepatocyte regeneration in a mouse model of acetaminophen toxicity. (Donahower BC, McCullough SS, Hennings L, Simpson PM, Stowe CD, Saad AG, Kurten RC, Hinson JA, James LP) J Pharmacol Exp Ther 2010 Jul;334(1):33-43 42 Citations |
| 1 | Transgenic mice expressing an intracellular fluorescent fusion of angiotensin II demonstrate renal thrombotic microangiopathy and elevated blood pressure. (Redding KM, Chen BL, Singh A, Re RN, Navar LG, Seth DM, Sigmund CD, Tang WW, Cook JL) Am J Physiol Heart Circ Physiol 2010 Jun;298(6):H1807-18 39 Citations |
| 1 | Efficient mammalian germline transgenesis by cis-enhanced Sleeping Beauty transposition. (Carlson DF, Geurts AM, Garbe JR, Park CW, Rangel-Filho A, O'Grady SM, Jacob HJ, Steer CJ, Largaespada DA, Fahrenkrug SC) Transgenic Res 2011 Feb;20(1):29-45 25 Citations |
| 1 | Chemoprevention of colorectal cancer by targeting APC-deficient cells for apoptosis. (Zhang L, Ren X, Alt E, Bai X, Huang S, Xu Z, Lynch PM, Moyer MP, Wen XF, Wu X) Nature 2010 Apr 15;464(7291):1058-61 127 Citations |
| 1 | Endothelin-1 inhibits the epithelial Na+ channel through betaPix/14-3-3/Nedd4-2. (Pavlov TS, Chahdi A, Ilatovskaya DV, Levchenko V, Vandewalle A, Pochynyuk O, Sorokin A, Staruschenko A) J Am Soc Nephrol 2010 May;21(5):833-43 59 Citations |
| 1 | Physiological basis of tingling paresthesia evoked by hydroxy-alpha-sanshool. (Lennertz RC, Tsunozaki M, Bautista DM, Stucky CL) J Neurosci 2010 Mar 24;30(12):4353-61 76 Citations |
| 1 | Estradiol-induced object memory consolidation in middle-aged female mice requires dorsal hippocampal extracellular signal-regulated kinase and phosphatidylinositol 3-kinase activation. (Fan L, Zhao Z, Orr PT, Chambers CH, Lewis MC, Frick KM) J Neurosci 2010 Mar 24;30(12):4390-400 132 Citations |
| 1 | Antidepressant-like effect of delta9-tetrahydrocannabinol and other cannabinoids isolated from Cannabis sativa L. (El-Alfy AT, Ivey K, Robinson K, Ahmed S, Radwan M, Slade D, Khan I, ElSohly M, Ross S) Pharmacol Biochem Behav 2010 Jun;95(4):434-42 237 Citations |
| 1 | Pleiotrophin regulates the expansion and regeneration of hematopoietic stem cells. (Himburg HA, Muramoto GG, Daher P, Meadows SK, Russell JL, Doan P, Chi JT, Salter AB, Lento WE, Reya T, Chao NJ, Chute JP) Nat Med 2010 Apr;16(4):475-82 239 Citations |
| 1 | Twists and turns in the search for the elusive renin processing enzyme: focus on "Cathepsin B is not the processing enzyme for mouse prorenin". (Gross KW, Gomez RA, Sigmund CD) Am J Physiol Regul Integr Comp Physiol 2010 May;298(5):R1209-11 6 Citations |
| 1 | Functional muscle analysis of the Tcap knockout mouse. (Markert CD, Meaney MP, Voelker KA, Grange RW, Dalley HW, Cann JK, Ahmed M, Bishwokarma B, Walker SJ, Yu SX, Brown M, Lawlor MW, Beggs AH, Childers MK) Hum Mol Genet 2010 Jun 01;19(11):2268-83 39 Citations |
| 2 | p38gamma MAPK cooperates with c-Jun in trans-activating matrix metalloproteinase 9. (Loesch M, Zhi HY, Hou SW, Qi XM, Li RS, Basir Z, Iftner T, Cuenda A, Chen G) J Biol Chem 2010 May 14;285(20):15149-15158 82 Citations |
| 1 | CXC chemokine receptor 4 is a cell surface receptor for extracellular ubiquitin. (Saini V, Marchese A, Majetschak M) J Biol Chem 2010 May 14;285(20):15566-15576 149 Citations |
| 1 | Ex vivo delivery of GDNF maintains motor function and prevents neuronal loss in a transgenic mouse model of Huntington's disease. (Ebert AD, Barber AE, Heins BM, Svendsen CN) Exp Neurol 2010 Jul;224(1):155-62 75 Citations |
| 1 | Emerging regulatory paradigms for control of gene expression by 1,25-dihydroxyvitamin D3. (Pike JW, Meyer MB, Martowicz ML, Bishop KA, Lee SM, Nerenz RD, Goetsch PD) J Steroid Biochem Mol Biol 2010 Jul;121(1-2):130-5 51 Citations |
| 1 | Epigenetic alterations regulate estradiol-induced enhancement of memory consolidation. (Zhao Z, Fan L, Frick KM) Proc Natl Acad Sci U S A 2010 Mar 23;107(12):5605-10 188 Citations |
| 1 | Mouse BMD quantitative trait loci show improved concordance with human genome-wide association loci when recalculated on a new, common mouse genetic map. (Ackert-Bicknell CL, Karasik D, Li Q, Smith RV, Hsu YH, Churchill GA, Paigen BJ, Tsaih SW) J Bone Miner Res 2010 Aug;25(8):1808-20 43 Citations |
| 1 | The G(0)/G(1) switch gene 2 regulates adipose lipolysis through association with adipose triglyceride lipase. (Yang X, Lu X, Lombès M, Rha GB, Chi YI, Guerin TM, Smart EJ, Liu J) Cell Metab 2010 Mar 03;11(3):194-205 399 Citations |
| 1 | The waved with open eyelids (woe) locus is a hypomorphic mouse mutation in Adam17. (Hassemer EL, Le Gall SM, Liegel R, McNally M, Chang B, Zeiss CJ, Dubielzig RD, Horiuchi K, Kimura T, Okada Y, Blobel CP, Sidjanin DJ) Genetics 2010 May;185(1):245-55 39 Citations |
| 2 | Allele-specific tumor spectrum in pten knockin mice. (Wang H, Karikomi M, Naidu S, Rajmohan R, Caserta E, Chen HZ, Rawahneh M, Moffitt J, Stephens JA, Fernandez SA, Weinstein M, Wang D, Sadee W, La Perle K, Stromberg P, Rosol TJ, Eng C, Ostrowski MC, Leone G) Proc Natl Acad Sci U S A 2010 Mar 16;107(11):5142-7 57 Citations |
| 1 | Enhanced proliferation and migration of vascular smooth muscle cells in response to vascular injury under hyperglycemic conditions is controlled by beta3 integrin signaling. (Panchatcharam M, Miriyala S, Yang F, Leitges M, Chrzanowska-Wodnicka M, Quilliam LA, Anaya P, Morris AJ, Smyth SS) Int J Biochem Cell Biol 2010 Jun;42(6):965-74 50 Citations |
| 1 | Histidine-rich glycoprotein modulates the anti-angiogenic effects of vasculostatin. (Klenotic PA, Huang P, Palomo J, Kaur B, Van Meir EG, Vogelbaum MA, Febbraio M, Gladson CL, Silverstein RL) Am J Pathol 2010 Apr;176(4):2039-50 46 Citations |
| 1 | Induction of human blood group a antigen expression on mouse cells, using lentiviral gene transduction. (Fan X, Lang H, Zhou X, Zhang L, Yin R, Maciejko J, Giannitsos V, Motyka B, Medin JA, Platt JL, West LJ) Hum Gene Ther 2010 Jul;21(7):877-90 12 Citations |
| 1 | Activation of the A(3) adenosine receptor inhibits fMLP-induced Rac activation in mouse bone marrow neutrophils. (van der Hoeven D, Gizewski ET, Auchampach JA) Biochem Pharmacol 2010 Jun 01;79(11):1667-73 10 Citations |
| 1 | An ets2-driven transcriptional program in tumor-associated macrophages promotes tumor metastasis. (Zabuawala T, Taffany DA, Sharma SM, Merchant A, Adair B, Srinivasan R, Rosol TJ, Fernandez S, Huang K, Leone G, Ostrowski MC) Cancer Res 2010 Feb 15;70(4):1323-33 107 Citations |
| 1 | A survey of airway responsiveness in 36 inbred mouse strains facilitates gene mapping studies and identification of quantitative trait loci. (Leme AS, Berndt A, Williams LK, Tsaih SW, Szatkiewicz JP, Verdugo R, Paigen B, Shapiro SD) Mol Genet Genomics 2010 Apr;283(4):317-26 31 Citations |
| 1 | VAV2 and VAV3 as candidate disease genes for spontaneous glaucoma in mice and humans. (Fujikawa K, Iwata T, Inoue K, Akahori M, Kadotani H, Fukaya M, Watanabe M, Chang Q, Barnett EM, Swat W) PLoS One 2010 Feb 04;5(2):e9050 49 Citations |
| 2 | A(3) adenosine receptor activation during reperfusion reduces infarct size through actions on bone marrow-derived cells. (Ge ZD, van der Hoeven D, Maas JE, Wan TC, Auchampach JA) J Mol Cell Cardiol 2010 Aug;49(2):280-6 44 Citations |
| 1 | Quantitative assessment of intestinal injury using a novel in vivo, near-infrared imaging technique. (Costantini TW, Eliceiri BP, Peterson CY, Loomis WH, Putnam JG, Baird A, Wolf P, Bansal V, Coimbra R) Mol Imaging 2010 Feb;9(1):30-9 17 Citations |
| 1 | Does peroxisome proliferator-activated receptor-gamma (PPAR gamma) protect from hypertension directly through effects in the vasculature? (Ketsawatsomkron P, Pelham CJ, Groh S, Keen HL, Faraci FM, Sigmund CD) J Biol Chem 2010 Mar 26;285(13):9311-9316 58 Citations |
| 1 | The effect of tyrosine nitration of L-type Ca2+ channels on excitation-transcription coupling in colonic inflammation. (Kang M, Ross GR, Akbarali HI) Br J Pharmacol 2010 Mar;159(6):1226-35 19 Citations |
| 1 | Neurotensin receptor type 1 regulates ethanol intoxication and consumption in mice. (Lee MR, Hinton DJ, Song JY, Lee KW, Choo C, Johng H, Unal SS, Richelson E, Choi DS) Pharmacol Biochem Behav 2010 Apr;95(2):235-41 31 Citations |
| 1 | Nanoparticulate cellular patches for cell-mediated tumoritropic delivery. (Cheng H, Kastrup CJ, Ramanathan R, Siegwart DJ, Ma M, Bogatyrev SR, Xu Q, Whitehead KA, Langer R, Anderson DG) ACS Nano 2010 Feb 23;4(2):625-31 134 Citations |
| 3 | Phospholipase C{gamma}1 is essential for T cell development, activation, and tolerance. (Fu G, Chen Y, Yu M, Podd A, Schuman J, He Y, Di L, Yassai M, Haribhai D, North PE, Gorski J, Williams CB, Wang D, Wen R) J Exp Med 2010 Feb 15;207(2):309-18 109 Citations |
| 1 | Hexaminolevulinate-mediated photodynamic purging of leukemia cells from BM. (Čunderlíková B, Vasovič V, Sieber F, Furre T, Nesland JM, Peng Q) Bone Marrow Transplant 2010 Oct;45(10):1553-61 5 Citations |
| 1 | Cholecystokinin knockout mice are resistant to high-fat diet-induced obesity. (Lo CM, King A, Samuelson LC, Kindel TL, Rider T, Jandacek RJ, Raybould HE, Woods SC, Tso P) Gastroenterology 2010 May;138(5):1997-2005 59 Citations |
| 1 | Two-point Dixon technique provides robust fat suppression for multi-mouse imaging. (Ragan DK, Bankson JA) J Magn Reson Imaging 2010 Feb;31(2):510-4 12 Citations |
| 1 | Altered glutamatergic neurotransmission in the striatum regulates ethanol sensitivity and intake in mice lacking ENT1. (Chen J, Nam HW, Lee MR, Hinton DJ, Choi S, Kim T, Kawamura T, Janak PH, Choi DS) Behav Brain Res 2010 Apr 02;208(2):636-42 53 Citations |
| 1 | Identification and characterization of the first small molecule inhibitor of MDMX. (Reed D, Shen Y, Shelat AA, Arnold LA, Ferreira AM, Zhu F, Mills N, Smithson DC, Regni CA, Bashford D, Cicero SA, Schulman BA, Jochemsen AG, Guy RK, Dyer MA) J Biol Chem 2010 Apr 02;285(14):10786-96 181 Citations |
| 1 | Compensatory responses to age-related decline in odor quality acuity: cholinergic neuromodulation and olfactory enrichment. (Mandairon N, Peace ST, Boudadi K, Boxhorn CE, Narla VA, Suffis SD, Cleland TA) Neurobiol Aging 2011 Dec;32(12):2254-65 28 Citations |
| 1 | Acid sphingomyelinase deficiency does not protect from graft-versus-host disease in transplant recipients with Niemann-Pick disease. (Tolar J, Eapen M, Orchard PJ, Blazar BR) Blood 2010 Jan 14;115(2):434-5 3 Citations |
| 1 | Lack of evidence for a pathogenic role of T-lymphocytes in an animal model for Charcot-Marie-Tooth disease 1A. (Kohl B, Groh J, Wessig C, Wiendl H, Kroner A, Martini R) Neurobiol Dis 2010 Apr;38(1):78-84 13 Citations |
| 1 | Increased renin production in mice with deletion of peroxisome proliferator-activated receptor-gamma in juxtaglomerular cells. (Desch M, Schreiber A, Schweda F, Madsen K, Friis UG, Weatherford ET, Sigmund CD, Sequeira Lopez ML, Gomez RA, Todorov VT) Hypertension 2010 Mar;55(3):660-6 24 Citations |
| 1 | StarD4-mediated translocation of 7-hydroperoxycholesterol to isolated mitochondria: deleterious effects and implications for steroidogenesis under oxidative stress conditions. (Korytowski W, Rodriguez-Agudo D, Pilat A, Girotti AW) Biochem Biophys Res Commun 2010 Jan 29;392(1):58-62 23 Citations |
| 1 | The microRNA-processing enzyme dicer maintains juxtaglomerular cells. (Sequeira-Lopez ML, Weatherford ET, Borges GR, Monteagudo MC, Pentz ES, Harfe BD, Carretero O, Sigmund CD, Gomez RA) J Am Soc Nephrol 2010 Mar;21(3):460-7 133 Citations |
| 1 | Reduced sox9 function promotes heart valve calcification phenotypes in vivo. (Peacock JD, Levay AK, Gillaspie DB, Tao G, Lincoln J) Circ Res 2010 Mar 05;106(4):712-9 107 Citations |
| 1 | Inhibition of aldehyde dehydrogenase expands hematopoietic stem cells with radioprotective capacity. (Muramoto GG, Russell JL, Safi R, Salter AB, Himburg HA, Daher P, Meadows SK, Doan P, Storms RW, Chao NJ, McDonnell DP, Chute JP) Stem Cells 2010 Mar 31;28(3):523-34 62 Citations |
| 2 | Distal interactions within the par3-VE-cadherin complex. (Tyler RC, Peterson FC, Volkman BF) Biochemistry 2010 Feb 09;49(5):951-7 48 Citations |
| 1 | Ectopic T-cell specificity and absence of perforin and granzyme B alleviate neural damage in oligodendrocyte mutant mice. (Kroner A, Ip CW, Thalhammer J, Nave KA, Martini R) Am J Pathol 2010 Feb;176(2):549-55 23 Citations |
| 1 | Tgif1 and Tgif2 regulate Nodal signaling and are required for gastrulation. (Powers SE, Taniguchi K, Yen W, Melhuish TA, Shen J, Walsh CA, Sutherland AE, Wotton D) Development 2010 Jan;137(2):249-59 53 Citations |
| 1 | Endothelial and vascular muscle PPARgamma in arterial pressure regulation: lessons from genetic interference and deficiency. (Sigmund CD) Hypertension 2010 Feb;55(2):437-44 38 Citations |
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| 1 | Francisella tularensis genes required for inhibition of the neutrophil respiratory burst and intramacrophage growth identified by random transposon mutagenesis of strain LVS. (Schulert GS, McCaffrey RL, Buchan BW, Lindemann SR, Hollenback C, Jones BD, Allen LA) Infect Immun 2009 Apr;77(4):1324-36 60 Citations |
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| 1 | Depletion of CD4 T cells enhances immunotherapy for neuroblastoma after syngeneic HSCT but compromises development of antitumor immune memory. (Jing W, Gershan JA, Johnson BD) Blood 2009 Apr 30;113(18):4449-57 40 Citations |
| 1 | Vasculostatin inhibits intracranial glioma growth and negatively regulates in vivo angiogenesis through a CD36-dependent mechanism. (Kaur B, Cork SM, Sandberg EM, Devi NS, Zhang Z, Klenotic PA, Febbraio M, Shim H, Mao H, Tucker-Burden C, Silverstein RL, Brat DJ, Olson JJ, Van Meir EG) Cancer Res 2009 Feb 01;69(3):1212-20 98 Citations |
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| 1 | p18Ink4c and p53 Act as tumor suppressors in cyclin D1-driven primitive neuroectodermal tumor. (Saab R, Rodriguez-Galindo C, Matmati K, Rehg JE, Baumer SH, Khoury JD, Billups C, Neale G, Helton KJ, Skapek SX) Cancer Res 2009 Jan 15;69(2):440-8 22 Citations |
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| 1 | Pharmacological manipulation of the RAR/RXR signaling pathway maintains the repopulating capacity of hematopoietic stem cells in culture. (Safi R, Muramoto GG, Salter AB, Meadows S, Himburg H, Russell L, Daher P, Doan P, Leibowitz MD, Chao NJ, McDonnell DP, Chute JP) Mol Endocrinol 2009 Feb;23(2):188-201 23 Citations |
| 1 | Retrovirally transduced murine T lymphocytes expressing FasL mediate effective killing of prostate cancer cells. (Symes JC, Siatskas C, Fowler DH, Medin JA) Cancer Gene Ther 2009 May;16(5):439-52 8 Citations |
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| 1 | MyD88-dependent, superoxide-initiated inflammation is necessary for flow-mediated inward remodeling of conduit arteries. (Tang PC, Qin L, Zielonka J, Zhou J, Matte-Martone C, Bergaya S, van Rooijen N, Shlomchik WD, Min W, Sessa WC, Pober JS, Tellides G) J Exp Med 2008 Dec 22;205(13):3159-71 58 Citations |
| 3 | Interleukin-23 secretion by donor antigen-presenting cells is critical for organ-specific pathology in graft-versus-host disease. (Das R, Chen X, Komorowski R, Hessner MJ, Drobyski WR) Blood 2009 Mar 05;113(10):2352-62 69 Citations |
| 1 | Cholangiocytes as immune modulators in rotavirus-induced murine biliary atresia. (Barnes BH, Tucker RM, Wehrmann F, Mack DG, Ueno Y, Mack CL) Liver Int 2009 Sep;29(8):1253-61 56 Citations |
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| 1 | Genetic basis of HDL variation in 129/SvImJ and C57BL/6J mice: importance of testing candidate genes in targeted mutant mice. (Su Z, Wang X, Tsaih SW, Zhang A, Cox A, Sheehan S, Paigen B) J Lipid Res 2009 Jan;50(1):116-25 20 Citations |
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| 1 | Ghrelin regulates gastric phase III-like contractions in freely moving conscious mice. (Zheng J, Ariga H, Taniguchi H, Ludwig K, Takahashi T) Neurogastroenterol Motil 2009 Jan;21(1):78-84 70 Citations |
| 1 | A stochastic model for cancer stem cell origin in metastatic colon cancer. (Odoux C, Fohrer H, Hoppo T, Guzik L, Stolz DB, Lewis DW, Gollin SM, Gamblin TC, Geller DA, Lagasse E) Cancer Res 2008 Sep 01;68(17):6932-41 140 Citations |
| 2 | Syx, a RhoA guanine exchange factor, is essential for angiogenesis in Vivo. (Garnaas MK, Moodie KL, Liu ML, Samant GV, Li K, Marx R, Baraban JM, Horowitz A, Ramchandran R) Circ Res 2008 Sep 26;103(7):710-6 55 Citations |
| 1 | Estradiol-induced enhancement of object memory consolidation involves hippocampal extracellular signal-regulated kinase activation and membrane-bound estrogen receptors. (Fernandez SM, Lewis MC, Pechenino AS, Harburger LL, Orr PT, Gresack JE, Schafe GE, Frick KM) J Neurosci 2008 Aug 27;28(35):8660-7 247 Citations |
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| 1 | Deficiency of LRP8 in mice is associated with altered platelet function and prolonged time for in vivo thrombosis. (Robertson JO, Li W, Silverstein RL, Topol EJ, Smith JD) Thromb Res 2009 Feb;123(4):644-52 25 Citations |
| 1 | Phorbol esters modulate spontaneous and Ca2+-evoked transmitter release via acting on both Munc13 and protein kinase C. (Lou X, Korogod N, Brose N, Schneggenburger R) J Neurosci 2008 Aug 13;28(33):8257-67 105 Citations |
| 1 | CD28 controls differentiation of regulatory T cells from naive CD4 T cells. (Guo F, Iclozan C, Suh WK, Anasetti C, Yu XZ) J Immunol 2008 Aug 15;181(4):2285-91 99 Citations |
| 1 | Tumor-derived endothelial cells exhibit aberrant Rho-mediated mechanosensing and abnormal angiogenesis in vitro. (Ghosh K, Thodeti CK, Dudley AC, Mammoto A, Klagsbrun M, Ingber DE) Proc Natl Acad Sci U S A 2008 Aug 12;105(32):11305-10 178 Citations |
| 1 | Morphine tolerance in the mouse ileum and colon. (Ross GR, Gabra BH, Dewey WL, Akbarali HI) J Pharmacol Exp Ther 2008 Nov;327(2):561-72 73 Citations |
| 2 | Endothelium-specific interference with peroxisome proliferator activated receptor gamma causes cerebral vascular dysfunction in response to a high-fat diet. (Beyer AM, de Lange WJ, Halabi CM, Modrick ML, Keen HL, Faraci FM, Sigmund CD) Circ Res 2008 Sep 12;103(6):654-61 86 Citations |
| 2 | Site-specific effects of PECAM-1 on atherosclerosis in LDL receptor-deficient mice. (Goel R, Schrank BR, Arora S, Boylan B, Fleming B, Miura H, Newman PJ, Molthen RC, Newman DK) Arterioscler Thromb Vasc Biol 2008 Nov;28(11):1996-2002 93 Citations |
| 1 | Genetic and environmental cofactors of Myc translocations in plasma cell tumor development in mice. (Janz S) J Natl Cancer Inst Monogr 2008(39):37-40 7 Citations |
| 1 | Umbilical cord blood regulatory T-cell expansion and functional effects of tumor necrosis factor receptor family members OX40 and 4-1BB expressed on artificial antigen-presenting cells. (Hippen KL, Harker-Murray P, Porter SB, Merkel SC, Londer A, Taylor DK, Bina M, Panoskaltsis-Mortari A, Rubinstein P, Van Rooijen N, Golovina TN, Suhoski MM, Miller JS, Wagner JE, June CH, Riley JL, Blazar BR) Blood 2008 Oct 01;112(7):2847-57 131 Citations |
| 1 | Expression of macrophage migration inhibitory factor by neuroblastoma leads to the inhibition of antitumor T cell reactivity in vivo. (Zhou Q, Yan X, Gershan J, Orentas RJ, Johnson BD) J Immunol 2008 Aug 01;181(3):1877-86 36 Citations |
| 1 | Targeted deletion of Rad9 in mouse skin keratinocytes enhances genotoxin-induced tumor development. (Hu Z, Liu Y, Zhang C, Zhao Y, He W, Han L, Yang L, Hopkins KM, Yang X, Lieberman HB, Hang H) Cancer Res 2008 Jul 15;68(14):5552-61 30 Citations |
| 1 | Dysregulated human renin expression in transgenic mice carrying truncated genomic constructs: evidence supporting the presence of insulators at the renin locus. (Zhou X, Weatherford ET, Liu X, Born E, Keen HL, Sigmund CD) Am J Physiol Renal Physiol 2008 Sep;295(3):F642-53 3 Citations |
| 1 | Global expression profiling identifies a novel biosignature for protein aggregation R120GCryAB cardiomyopathy in mice. (Rajasekaran NS, Firpo MA, Milash BA, Weiss RB, Benjamin IJ) Physiol Genomics 2008 Oct 08;35(2):165-72 26 Citations |
| 1 | IL-12 immunotherapy of murine leukaemia: comparison of systemic versus gene modified cell therapy. (Labbe A, Nelles M, Walia J, Jia L, Furlonger C, Nonaka T, Medin JA, Paige CJ) J Cell Mol Med 2009 Aug;13(8B):1962-1976 19 Citations |
| 1 | Autophagy is an adaptive response in desmin-related cardiomyopathy. (Tannous P, Zhu H, Johnstone JL, Shelton JM, Rajasekaran NS, Benjamin IJ, Nguyen L, Gerard RD, Levine B, Rothermel BA, Hill JA) Proc Natl Acad Sci U S A 2008 Jul 15;105(28):9745-50 222 Citations |
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| 1 | Deglycosylated anti-Abeta antibody dose-response effects on pathology and memory in APP transgenic mice. (Karlnoski RA, Rosenthal A, Alamed J, Ronan V, Gordon MN, Gottschall PE, Grimm J, Pons J, Morgan D) J Neuroimmune Pharmacol 2008 Sep;3(3):187-97 23 Citations |
| 1 | 20-HETE mediates proliferation of renal epithelial cells in polycystic kidney disease. (Park F, Sweeney WE, Jia G, Roman RJ, Avner ED) J Am Soc Nephrol 2008 Oct;19(10):1929-39 45 Citations |
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| 1 | Cross-talk between notch and the estrogen receptor in breast cancer suggests novel therapeutic approaches. (Rizzo P, Miao H, D'Souza G, Osipo C, Song LL, Yun J, Zhao H, Mascarenhas J, Wyatt D, Antico G, Hao L, Yao K, Rajan P, Hicks C, Siziopikou K, Selvaggi S, Bashir A, Bhandari D, Marchese A, Lendahl U, Qin JZ, Tonetti DA, Albain K, Nickoloff BJ, Miele L) Cancer Res 2008 Jul 01;68(13):5226-35 309 Citations |
| 1 | Differential effects of acute progesterone administration on spatial and object memory in middle-aged and aged female C57BL/6 mice. (Lewis MC, Orr PT, Frick KM) Horm Behav 2008 Aug;54(3):455-62 40 Citations |
| 2 | Activation of the A(3) adenosine receptor suppresses superoxide production and chemotaxis of mouse bone marrow neutrophils. (van der Hoeven D, Wan TC, Auchampach JA) Mol Pharmacol 2008 Sep;74(3):685-96 71 Citations |
| 1 | Histopathology of experimentally induced asthma in a murine model of sickle cell disease. (Nandedkar SD, Feroah TR, Hutchins W, Weihrauch D, Konduri KS, Wang J, Strunk RC, DeBaun MR, Hillery CA, Pritchard KA) Blood 2008 Sep 15;112(6):2529-38 47 Citations |
| 2 | A Francisella tularensis Schu S4 purine auxotroph is highly attenuated in mice but offers limited protection against homologous intranasal challenge. (Pechous RD, McCarthy TR, Mohapatra NP, Soni S, Penoske RM, Salzman NH, Frank DW, Gunn JS, Zahrt TC) PLoS One 2008 Jun 25;3(6):e2487 64 Citations |
| 1 | Endothelial-specific ablation of serum response factor causes hemorrhaging, yolk sac vascular failure, and embryonic lethality. (Holtz ML, Misra RP) BMC Dev Biol 2008 Jun 20;8:65 17 Citations |
| 1 | Constitutive CXCL12 expression induces anoikis in colorectal carcinoma cells. (Wendt MK, Drury LJ, Vongsa RA, Dwinell MB) Gastroenterology 2008 Aug;135(2):508-17 45 Citations |
| 1 | Origin of CD11b+ macrophage-like cells in the CNS of PLP-overexpressing mice: low influx of haematogenous macrophages and unchanged blood-brain-barrier in the optic nerve. (Ip CW, Kohl B, Kleinschnitz C, Reuss B, Nave KA, Kroner A, Martini R) Mol Cell Neurosci 2008 Aug;38(4):489-94 13 Citations |
| 1 | Deletion of PI3K-p85alpha gene impairs lineage commitment, terminal maturation, cytokine generation and cytotoxicity of NK cells. (Awasthi A, Samarakoon A, Dai X, Wen R, Wang D, Malarkannan S) Genes Immun 2008 Sep;9(6):522-35 29 Citations |
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| 1 | G-protein binding features and regulation of the RalGDS family member, RGL2. (Ferro E, Magrini D, Guazzi P, Fischer TH, Pistolesi S, Pogni R, White GC, Trabalzini L) Biochem J 2008 Oct 01;415(1):145-54 7 Citations |
| 1 | Salt-sensitive hypertension and cardiac hypertrophy in mice deficient in the ubiquitin ligase Nedd4-2. (Shi PP, Cao XR, Sweezer EM, Kinney TS, Williams NR, Husted RF, Nair R, Weiss RM, Williamson RA, Sigmund CD, Snyder PM, Staub O, Stokes JB, Yang B) Am J Physiol Renal Physiol 2008 Aug;295(2):F462-70 139 Citations |
| 1 | E1A oncogene enhancement of caspase-2-mediated mitochondrial injury sensitizes cells to macrophage nitric oxide-induced apoptosis. (Radke JR, Siddiqui ZK, Miura TA, Routes JM, Cook JL) J Immunol 2008 Jun 15;180(12):8272-9 12 Citations |
| 1 | TGF-beta-dependent suppressive function of Tregs requires wild-type levels of CD18 in a mouse model of psoriasis. (Wang H, Peters T, Sindrilaru A, Kess D, Oreshkova T, Yu XZ, Seier AM, Schreiber H, Wlaschek M, Blakytny R, Röhrbein J, Schulz G, Weiss JM, Scharffetter-Kochanek K) J Clin Invest 2008 Jul;118(7):2629-39 59 Citations |
| 1 | Estradiol-induced enhancement of object memory consolidation involves NMDA receptors and protein kinase A in the dorsal hippocampus of female C57BL/6 mice. (Lewis MC, Kerr KM, Orr PT, Frick KM) Behav Neurosci 2008 Jun;122(3):716-21 96 Citations |
| 1 | An imaging workflow for characterizing phenotypical change in large histological mouse model datasets. (Mosaliganti K, Pan T, Ridgway R, Sharp R, Cooper L, Gulacy A, Sharma A, Irfanoglu O, Machiraju R, Kurc T, de Bruin A, Wenzel P, Leone G, Saltz J, Huang K) J Biomed Inform 2008 Dec;41(6):863-73 11 Citations |
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| 2 | Syngeneic transplantation of hematopoietic stem cells that are genetically modified to express factor VIII in platelets restores hemostasis to hemophilia A mice with preexisting FVIII immunity. (Shi Q, Fahs SA, Wilcox DA, Kuether EL, Morateck PA, Mareno N, Weiler H, Montgomery RR) Blood 2008 Oct 01;112(7):2713-21 87 Citations |
| 1 | Quantitative trait loci for urinary albumin in crosses between C57BL/6J and A/J inbred mice in the presence and absence of Apoe. (Doorenbos C, Tsaih SW, Sheehan S, Ishimori N, Navis G, Churchill G, Dipetrillo K, Korstanje R) Genetics 2008 May;179(1):693-9 15 Citations |
| 1 | Maternal Par4 and platelets contribute to defective placenta formation in mouse embryos lacking thrombomodulin. (Sood R, Sholl L, Isermann B, Zogg M, Coughlin SR, Weiler H) Blood 2008 Aug 01;112(3):585-91 36 Citations |
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| 1 | Fibrochondrogenesis of hESCs: growth factor combinations and cocultures. (Hoben GM, Willard VP, Athanasiou KA) Stem Cells Dev 2009 Mar;18(2):283-92 69 Citations |
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| 1 | Nectin-1 (HveC) is expressed at high levels in neural subtypes that regulate radial migration of cortical and cerebellar neurons of the developing human and murine brain. (Prandovszky E, Horváth S, Gellért L, Kovács SK, Janka Z, Toldi J, Shukla D, Vályi-Nagy T) J Neurovirol 2008 Apr;14(2):164-72 12 Citations |
| 1 | Activation of the constitutive androstane receptor decreases HDL in wild-type and human apoA-I transgenic mice. (Masson D, Qatanani M, Sberna AL, Xiao R, Pais de Barros JP, Grober J, Deckert V, Athias A, Gambert P, Lagrost L, Moore DD, Assem M) J Lipid Res 2008 Aug;49(8):1682-91 37 Citations |
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| 1 | Selective delivery of beta cell antigen to dendritic cells in vivo leads to deletion and tolerance of autoreactive CD8+ T cells in NOD mice. (Mukhopadhaya A, Hanafusa T, Jarchum I, Chen YG, Iwai Y, Serreze DV, Steinman RM, Tarbell KV, DiLorenzo TP) Proc Natl Acad Sci U S A 2008 Apr 29;105(17):6374-9 124 Citations |
| 1 | Type IV pili in Francisella tularensis: roles of pilF and pilT in fiber assembly, host cell adherence, and virulence. (Chakraborty S, Monfett M, Maier TM, Benach JL, Frank DW, Thanassi DG) Infect Immun 2008 Jul;76(7):2852-61 67 Citations |
| 2 | Design of (N)-methanocarba adenosine 5'-uronamides as species-independent A3 receptor-selective agonists. (Melman A, Gao ZG, Kumar D, Wan TC, Gizewski E, Auchampach JA, Jacobson KA) Bioorg Med Chem Lett 2008 May 01;18(9):2813-9 43 Citations |
| 1 | B7-H1 restricts neuroantigen-specific T cell responses and confines inflammatory CNS damage: implications for the lesion pathogenesis of multiple sclerosis. (Ortler S, Leder C, Mittelbronn M, Zozulya AL, Knolle PA, Chen L, Kroner A, Wiendl H) Eur J Immunol 2008 Jun;38(6):1734-44 67 Citations |
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| 1 | Candidate genes for obesity revealed from a C57BL/6J x 129S1/SvImJ intercross. (Su Z, Korstanje R, Tsaih SW, Paigen B) Int J Obes (Lond) 2008 Jul;32(7):1180-9 29 Citations |
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| 1 | The significance of arginase I administration on the survival of mice bearing NS-1 myeloma cells. (Wang SR, Hou S, Wang A, Chang YJ, Liu CT, Tsay GJ, Wei CC) J Surg Res 2009 Jan;151(1):28-32 5 Citations |
| 2 | An alternatively spliced isoform of PECAM-1 is expressed at high levels in human and murine tissues, and suggests a novel role for the C-terminus of PECAM-1 in cytoprotective signaling. (Bergom C, Paddock C, Gao C, Holyst T, Newman DK, Newman PJ) J Cell Sci 2008 Apr 15;121(Pt 8):1235-42 15 Citations |
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| 1 | Gene expression signatures of radiation response are specific, durable and accurate in mice and humans. (Meadows SK, Dressman HK, Muramoto GG, Himburg H, Salter A, Wei Z, Ginsburg GS, Chao NJ, Nevins JR, Chute JP) PLoS One 2008 Apr 02;3(4):e1912 102 Citations |
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| 1 | Candidate genes for plasma triglyceride, FFA, and glucose revealed from an intercross between inbred mouse strains NZB/B1NJ and NZW/LacJ. (Su Z, Tsaih SW, Szatkiewicz J, Shen Y, Paigen B) J Lipid Res 2008 Jul;49(7):1500-10 19 Citations |
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| 1 | Topical interleukin-1 receptor antagonist inhibits inflammatory cell infiltration into the cornea. (Stapleton WM, Chaurasia SS, Medeiros FW, Mohan RR, Sinha S, Wilson SE) Exp Eye Res 2008 May;86(5):753-7 51 Citations |
| 1 | Tom1l2 hypomorphic mice exhibit increased incidence of infections and tumors and abnormal immunologic response. (Girirajan S, Hauck PM, Williams S, Vlangos CN, Szomju BB, Solaymani-Kohal S, Mosier PD, White KL Jr, McCoy K, Elsea SH) Mamm Genome 2008 Apr;19(4):246-62 20 Citations |
| 1 | Reversal of axonal loss and disability in a mouse model of progressive multiple sclerosis. (Basso AS, Frenkel D, Quintana FJ, Costa-Pinto FA, Petrovic-Stojkovic S, Puckett L, Monsonego A, Bar-Shir A, Engel Y, Gozin M, Weiner HL) J Clin Invest 2008 Apr;118(4):1532-43 208 Citations |
| 1 | CD36 mediates both cellular uptake of very long chain fatty acids and their intestinal absorption in mice. (Drover VA, Nguyen DV, Bastie CC, Darlington YF, Abumrad NA, Pessin JE, London E, Sahoo D, Phillips MC) J Biol Chem 2008 May 09;283(19):13108-15 133 Citations |
| 1 | Defects in breathing and thermoregulation in mice with near-complete absence of central serotonin neurons. (Hodges MR, Tattersall GJ, Harris MB, McEvoy SD, Richerson DN, Deneris ES, Johnson RL, Chen ZF, Richerson GB) J Neurosci 2008 Mar 05;28(10):2495-505 284 Citations |
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| 2 | Interference with PPAR gamma function in smooth muscle causes vascular dysfunction and hypertension. (Halabi CM, Beyer AM, de Lange WJ, Keen HL, Baumbach GL, Faraci FM, Sigmund CD) Cell Metab 2008 Mar;7(3):215-26 149 Citations |
| 2 | Species and strain differences in rodent sciatic nerve anatomy: implications for studies of neuropathic pain. (Rigaud M, Gemes G, Barabas ME, Chernoff DI, Abram SE, Stucky CL, Hogan QH) Pain 2008 May;136(1-2):188-201 229 Citations |
| 1 | Oxidative stress through activation of NAD(P)H oxidase in hypertensive mice with spontaneous intracranial hemorrhage. (Wakisaka Y, Miller JD, Chu Y, Baumbach GL, Wilson S, Faraci FM, Sigmund CD, Heistad DD) J Cereb Blood Flow Metab 2008 Jun;28(6):1175-85 29 Citations |
| 1 | A GATA-1-regulated microRNA locus essential for erythropoiesis. (Dore LC, Amigo JD, Dos Santos CO, Zhang Z, Gai X, Tobias JW, Yu D, Klein AM, Dorman C, Wu W, Hardison RC, Paw BH, Weiss MJ) Proc Natl Acad Sci U S A 2008 Mar 04;105(9):3333-8 299 Citations |
| 1 | The EtpA exoprotein of enterotoxigenic Escherichia coli promotes intestinal colonization and is a protective antigen in an experimental model of murine infection. (Roy K, Hamilton D, Allen KP, Randolph MP, Fleckenstein JM) Infect Immun 2008 May;76(5):2106-12 63 Citations |
| 2 | Interference with PPARgamma signaling causes cerebral vascular dysfunction, hypertrophy, and remodeling. (Beyer AM, Baumbach GL, Halabi CM, Modrick ML, Lynch CM, Gerhold TD, Ghoneim SM, de Lange WJ, Keen HL, Tsai YS, Maeda N, Sigmund CD, Faraci FM) Hypertension 2008 Apr;51(4):867-71 102 Citations |
| 1 | Use of a cryptic splice site for the expression of huntingtin interacting protein 1 in select normal and neoplastic tissues. (Graves CW, Philips ST, Bradley SV, Oravecz-Wilson KI, Li L, Gauvin A, Ross TS) Cancer Res 2008 Feb 15;68(4):1064-73 5 Citations |
| 1 | Primary naive and interleukin-2-activated natural killer cells do not support efficient ectromelia virus replication. (Parker AK, Yokoyama WM, Corbett JA, Chen N, Buller RML) J Gen Virol 2008 Mar;89(Pt 3):751-759 6 Citations |
| 1 | Formation of smooth muscle alpha actin filaments in CD34+ bone marrow cells on arterial elastic laminae: potential role of SH2 domain-containing protein tyrosine phosphatase-1. (Liu SQ, Tefft BJ, Zhang A, Zhang LQ, Wu YH) Matrix Biol 2008 May;27(4):282-94 6 Citations |
| 2 | Endocannabinoid signaling mediates cocaine-induced inhibitory synaptic plasticity in midbrain dopamine neurons. (Pan B, Hillard CJ, Liu QS) J Neurosci 2008 Feb 06;28(6):1385-97 126 Citations |
| 1 | Differential display of DNA-binding proteins reveals heat-shock factor 1 as a circadian transcription factor. (Reinke H, Saini C, Fleury-Olela F, Dibner C, Benjamin IJ, Schibler U) Genes Dev 2008 Feb 01;22(3):331-45 191 Citations |
| 2 | Direct evidence for epithelial-mesenchymal transitions in breast cancer. (Trimboli AJ, Fukino K, de Bruin A, Wei G, Shen L, Tanner SM, Creasap N, Rosol TJ, Robinson ML, Eng C, Ostrowski MC, Leone G) Cancer Res 2008 Feb 01;68(3):937-45 323 Citations |
| 1 | Hepatic fatty acid transporter Cd36 is a common target of LXR, PXR, and PPARgamma in promoting steatosis. (Zhou J, Febbraio M, Wada T, Zhai Y, Kuruba R, He J, Lee JH, Khadem S, Ren S, Li S, Silverstein RL, Xie W) Gastroenterology 2008 Feb;134(2):556-67 518 Citations |
| 1 | Visualization of microtubule growth in living platelets reveals a dynamic marginal band with multiple microtubules. (Patel-Hett S, Richardson JL, Schulze H, Drabek K, Isaac NA, Hoffmeister K, Shivdasani RA, Bulinski JC, Galjart N, Hartwig JH, Italiano JE Jr) Blood 2008 May 01;111(9):4605-16 131 Citations |
| 1 | Secondary metabolites from three Florida sponges with antidepressant activity. (Kochanowska AJ, Rao KV, Childress S, El-Alfy A, Matsumoto RR, Kelly M, Stewart GS, Sufka KJ, Hamann MT) J Nat Prod 2008 Feb;71(2):186-9 69 Citations |
| 1 | Pharmacologic targeting of a stem/progenitor population in vivo is associated with enhanced bone regeneration in mice. (Mukherjee S, Raje N, Schoonmaker JA, Liu JC, Hideshima T, Wein MN, Jones DC, Vallet S, Bouxsein ML, Pozzi S, Chhetri S, Seo YD, Aronson JP, Patel C, Fulciniti M, Purton LE, Glimcher LH, Lian JB, Stein G, Anderson KC, Scadden DT) J Clin Invest 2008 Feb;118(2):491-504 221 Citations |
| 1 | An enhancer 20 kilobases upstream of the human receptor activator of nuclear factor-kappaB ligand gene mediates dominant activation by 1,25-dihydroxyvitamin D3. (Nerenz RD, Martowicz ML, Pike JW) Mol Endocrinol 2008 May;22(5):1044-56 44 Citations |
| 2 | Synergistic function of E2F7 and E2F8 is essential for cell survival and embryonic development. (Li J, Ran C, Li E, Gordon F, Comstock G, Siddiqui H, Cleghorn W, Chen HZ, Kornacker K, Liu CG, Pandit SK, Khanizadeh M, Weinstein M, Leone G, de Bruin A) Dev Cell 2008 Jan;14(1):62-75 181 Citations |
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| 1 | An in vitro and in vivo disconnect uncovered through high-throughput identification of botulinum neurotoxin A antagonists. (Eubanks LM, Hixon MS, Jin W, Hong S, Clancy CM, Tepp WH, Baldwin MR, Malizio CJ, Goodnough MC, Barbieri JT, Johnson EA, Boger DL, Dickerson TJ, Janda KD) Proc Natl Acad Sci U S A 2007 Feb 20;104(8):2602-7 110 Citations |
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| 1 | Cellular expression requirements for inhibition of type 1 diabetes by a dominantly protective major histocompatibility complex haplotype. (Chen YG, Silveira PA, Osborne MA, Chapman HD, Serreze DV) Diabetes 2007 Feb;56(2):424-30 11 Citations |
| 1 | Mouse model of oral infection with virulent type A Francisella tularensis. (KuoLee R, Zhao X, Austin J, Harris G, Conlan JW, Chen W) Infect Immun 2007 Apr;75(4):1651-60 28 Citations |
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| 1 | Simultaneous generation of CD34+ primitive hematopoietic cells and CD73+ mesenchymal stem cells from human embryonic stem cells cocultured with murine OP9 stromal cells. (Trivedi P, Hematti P) Exp Hematol 2007 Jan;35(1):146-54 66 Citations |
| 1 | Loss of apolipoprotein E exacerbates the neonatal lethality of the Smith-Lemli-Opitz syndrome mouse. (Solcà C, Pandit B, Yu H, Tint GS, Patel SB) Mol Genet Metab 2007 May;91(1):7-14 11 Citations |
| 1 | Analog of H2 relaxin exhibits antagonistic properties and impairs prostate tumor growth. (Silvertown JD, Symes JC, Neschadim A, Nonaka T, Kao JC, Summerlee AJ, Medin JA) FASEB J 2007 Mar;21(3):754-65 53 Citations |
| 1 | Xenofuranones A and B: phenylpyruvate dimers from Xenorhabdus szentirmaii. (Brachmann AO, Forst S, Furgani GM, Fodor A, Bode HB) J Nat Prod 2006 Dec;69(12):1830-2 61 Citations |
| 1 | B cell lymphoma 10 is essential for FcepsilonR-mediated degranulation and IL-6 production in mast cells. (Chen Y, Pappu BP, Zeng H, Xue L, Morris SW, Lin X, Wen R, Wang D) J Immunol 2007 Jan 01;178(1):49-57 22 Citations |
| 1 | Cancer immunotherapy using virally transduced dendritic cells: animal studies and human clinical trials. (Mossoba ME, Medin JA) Expert Rev Vaccines 2006 Oct;5(5):717-32 24 Citations |
| 1 | Cloning and characterization of zebrafish (Danio rerio) cyclin-dependent kinase 5. (Kanungo J, Li BS, Goswami M, Zheng YL, Ramchandran R, Pant HC) Neurosci Lett 2007 Feb 02;412(3):233-8 17 Citations |
| 1 | Involvement of MAPKs in endostatin-mediated regulation of blood-retinal barrier function. (Campbell M, Collery R, McEvoy A, Gardiner TA, Stitt AW, Brankin B) Curr Eye Res 2006 Dec;31(12):1033-45 30 Citations |
| 1 | E2f1, E2f2, and E2f3 control E2F target expression and cellular proliferation via a p53-dependent negative feedback loop. (Timmers C, Sharma N, Opavsky R, Maiti B, Wu L, Wu J, Orringer D, Trikha P, Saavedra HI, Leone G) Mol Cell Biol 2007 Jan;27(1):65-78 85 Citations |
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| 1 | The Rat Genome Database, update 2007--easing the path from disease to data and back again. (Twigger SN, Shimoyama M, Bromberg S, Kwitek AE, Jacob HJ, RGD Team) Nucleic Acids Res 2007 Jan;35(Database issue):D658-62 109 Citations |
| 1 | Novel in vivo imaging shows up-regulation of death receptors by paclitaxel and correlates with enhanced antitumor effects of receptor agonist antibodies. (Gong J, Yang D, Kohanim S, Humphreys R, Broemeling L, Kurzrock R) Mol Cancer Ther 2006 Dec;5(12):2991-3000 33 Citations |
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| 1 | Differential helical orientations among related G protein-coupled receptors provide a novel mechanism for selectivity. Studies with salvinorin A and the kappa-opioid receptor. (Vortherms TA, Mosier PD, Westkaemper RB, Roth BL) J Biol Chem 2007 Feb 02;282(5):3146-56 34 Citations |
| 1 | ADME transcriptome in Hispanic versus White donor livers: evidence of a globally enhanced NR1I3 (CAR, constitutive androstane receptor) gene signature in Hispanics. (Finkelstein D, Lamba V, Assem M, Rengelshausen J, Yasuda K, Strom S, Schuetz E) Xenobiotica 2006;36(10-11):989-1012 12 Citations |
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| 1 | Transplantation of vascular endothelial cells mediates the hematopoietic recovery and survival of lethally irradiated mice. (Chute JP, Muramoto GG, Salter AB, Meadows SK, Rickman DW, Chen B, Himburg HA, Chao NJ) Blood 2007 Mar 15;109(6):2365-72 83 Citations |
| 1 | A protein interaction network for pluripotency of embryonic stem cells. (Wang J, Rao S, Chu J, Shen X, Levasseur DN, Theunissen TW, Orkin SH) Nature 2006 Nov 16;444(7117):364-8 940 Citations |
| 1 | Beta common receptor inactivation attenuates myeloproliferative disease in Nf1 mutant mice. (Kim A, Morgan K, Hasz DE, Wiesner SM, Lauchle JO, Geurts JL, Diers MD, Le DT, Kogan SC, Parada LF, Shannon K, Largaespada DA) Blood 2007 Feb 15;109(4):1687-91 23 Citations |
| 1 | Gammadelta T cells do not require fully functional cytotoxic pathways or the ability to recognize recipient alloantigens to prevent graft rejection. (Vodanovic-Jankovic S, Drobyski WR) Biol Blood Marrow Transplant 2006 Nov;12(11):1125-34 6 Citations |
| 1 | Partial versus full allogeneic hemopoietic chimerization is a preferential means to inhibit type 1 diabetes as the latter induces generalized immunosuppression. (Serreze DV, Osborne MA, Chen YG, Chapman HD, Pearson T, Brehm MA, Greiner DL) J Immunol 2006 Nov 15;177(10):6675-84 23 Citations |
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| 1 | ColVa1 and ColXIa1 are required for myocardial morphogenesis and heart valve development. (Lincoln J, Florer JB, Deutsch GH, Wenstrup RJ, Yutzey KE) Dev Dyn 2006 Dec;235(12):3295-305 59 Citations |
| 2 | Differential and nonredundant roles of phospholipase Cgamma2 and phospholipase Cgamma1 in the terminal maturation of NK cells. (Regunathan J, Chen Y, Kutlesa S, Dai X, Bai L, Wen R, Wang D, Malarkannan S) J Immunol 2006 Oct 15;177(8):5365-76 43 Citations |
| 2 | Gene mutations and genomic rearrangements in the mouse as a result of transposon mobilization from chromosomal concatemers. (Geurts AM, Collier LS, Geurts JL, Oseth LL, Bell ML, Mu D, Lucito R, Godbout SA, Green LE, Lowe SW, Hirsch BA, Leinwand LA, Largaespada DA) PLoS Genet 2006 Sep 29;2(9):e156 85 Citations |
| 1 | Association between the C3435T polymorphism of the MDR1 gene and Crohn's disease. (Lal S, Stempak JM, Law C, Elkadri AA, Steinhart AH, Silverberg MS) Inflamm Bowel Dis 2006 Oct;12(10):1006-7 6 Citations |
| 1 | Control of the p53-p21CIP1 Axis by E2f1, E2f2, and E2f3 is essential for G1/S progression and cellular transformation. (Sharma N, Timmers C, Trikha P, Saavedra HI, Obery A, Leone G) J Biol Chem 2006 Nov 24;281(47):36124-31 61 Citations |
| 2 | Improved cardiac function in infarcted mice after treatment with pluripotent embryonic stem cells. (Nelson TJ, Ge ZD, Van Orman J, Barron M, Rudy-Reil D, Hacker TA, Misra R, Duncan SA, Auchampach JA, Lough JW) Anat Rec A Discov Mol Cell Evol Biol 2006 Nov;288(11):1216-24 54 Citations |
| 1 | The human renin kidney enhancer is required to maintain base-line renin expression but is dispensable for tissue-specific, cell-specific, and regulated expression. (Zhou X, Davis DR, Sigmund CD) J Biol Chem 2006 Nov 17;281(46):35296-304 33 Citations |
| 1 | Solenopsin, the alkaloidal component of the fire ant (Solenopsis invicta), is a naturally occurring inhibitor of phosphatidylinositol-3-kinase signaling and angiogenesis. (Arbiser JL, Kau T, Konar M, Narra K, Ramchandran R, Summers SA, Vlahos CJ, Ye K, Perry BN, Matter W, Fischl A, Cook J, Silver PA, Bain J, Cohen P, Whitmire D, Furness S, Govindarajan B, Bowen JP) Blood 2007 Jan 15;109(2):560-5 91 Citations |
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| 1 | Nuclear factor-kappaB maintains TRAIL resistance in human pancreatic cancer cells. (Khanbolooki S, Nawrocki ST, Arumugam T, Andtbacka R, Pino MS, Kurzrock R, Logsdon CD, Abbruzzese JL, McConkey DJ) Mol Cancer Ther 2006 Sep;5(9):2251-60 125 Citations |
| 1 | Mll partial tandem duplication induces aberrant Hox expression in vivo via specific epigenetic alterations. (Dorrance AM, Liu S, Yuan W, Becknell B, Arnoczky KJ, Guimond M, Strout MP, Feng L, Nakamura T, Yu L, Rush LJ, Weinstein M, Leone G, Wu L, Ferketich A, Whitman SP, Marcucci G, Caligiuri MA) J Clin Invest 2006 Oct;116(10):2707-16 108 Citations |
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| 1 | A CD36-dependent signaling cascade is necessary for macrophage foam cell formation. (Rahaman SO, Lennon DJ, Febbraio M, Podrez EA, Hazen SL, Silverstein RL) Cell Metab 2006 Sep;4(3):211-21 444 Citations |
| 1 | Complex genetic architecture revealed by analysis of high-density lipoprotein cholesterol in chromosome substitution strains and F2 crosses. (Stylianou IM, Tsaih SW, DiPetrillo K, Ishimori N, Li R, Paigen B, Churchill G) Genetics 2006 Oct;174(2):999-1007 29 Citations |
| 1 | Unraveling the transcriptional network controlling ES cell pluripotency. (Rao S, Orkin SH) Genome Biol 2006;7(8):230 35 Citations |
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| 1 | Ceruloplasmin is a NO oxidase and nitrite synthase that determines endocrine NO homeostasis. (Shiva S, Wang X, Ringwood LA, Xu X, Yuditskaya S, Annavajjhala V, Miyajima H, Hogg N, Harris ZL, Gladwin MT) Nat Chem Biol 2006 Sep;2(9):486-93 323 Citations |
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| 1 | Microarray analysis of differentially expressed genes in mouse bone marrow tissues after ionizing radiation. (Dai JM, Sun DC, Lin RX, Yang J, Lou S, Wang SQ) Int J Radiat Biol 2006 Jul;82(7):511-21 19 Citations |
| 1 | A preliminary study on antimetastatic activity of Thuja occidentalis L. in mice model. (Sunila ES, Kuttan G) Immunopharmacol Immunotoxicol 2006;28(2):269-80 41 Citations |
| 1 | Femur mechanical properties in the F2 progeny of an NZB/B1NJ x RF/J cross are regulated predominantly by genetic loci that regulate bone geometry. (Wergedal JE, Ackert-Bicknell CL, Tsaih SW, Sheng MH, Li R, Mohan S, Beamer WG, Churchill GA, Baylink DJ) J Bone Miner Res 2006 Aug;21(8):1256-66 30 Citations |
| 1 | Role of persistent sodium current in bursting activity of mouse neocortical networks in vitro. (van Drongelen W, Koch H, Elsen FP, Lee HC, Mrejeru A, Doren E, Marcuccilli CJ, Hereld M, Stevens RL, Ramirez JM) J Neurophysiol 2006 Nov;96(5):2564-77 56 Citations |
| 1 | Construction and characterization of an attenuated purine auxotroph in a Francisella tularensis live vaccine strain. (Pechous R, Celli J, Penoske R, Hayes SF, Frank DW, Zahrt TC) Infect Immun 2006 Aug;74(8):4452-61 66 Citations |
| 1 | Gene transfer of pigment epithelium-derived factor suppresses tumor growth and angiogenesis in a hepatoblastoma xenograft model. (Browne M, Stellmach V, Cornwell M, Chung C, Doll JA, Lee EJ, Jameson JL, Reynolds M, Superina RA, Abramson LP, Crawford SE) Pediatr Res 2006 Sep;60(3):282-7 26 Citations |
| 1 | Evolution of melanopsin photoreceptors: discovery and characterization of a new melanopsin in nonmammalian vertebrates. (Bellingham J, Chaurasia SS, Melyan Z, Liu C, Cameron MA, Tarttelin EE, Iuvone PM, Hankins MW, Tosini G, Lucas RJ) PLoS Biol 2006 Jul;4(8):e254 168 Citations |
| 1 | Sequence analysis of the complete mitochondrial DNA in 10 commonly used inbred rat strains. (Schlick NE, Jensen-Seaman MI, Orlebeke K, Kwitek AE, Jacob HJ, Lazar J) Am J Physiol Cell Physiol 2006 Dec;291(6):C1183-92 40 Citations |
| 1 | Structural model analysis of multiple quantitative traits. (Li R, Tsaih SW, Shockley K, Stylianou IM, Wergedal J, Paigen B, Churchill GA) PLoS Genet 2006 Jul;2(7):e114 154 Citations |
| 2 | Pain with no gain: allodynia following neural stem cell transplantation in spinal cord injury. (Macias MY, Syring MB, Pizzi MA, Crowe MJ, Alexanian AR, Kurpad SN) Exp Neurol 2006 Oct;201(2):335-48 129 Citations |
| 2 | Factor VIII ectopically targeted to platelets is therapeutic in hemophilia A with high-titer inhibitory antibodies. (Shi Q, Wilcox DA, Fahs SA, Weiler H, Wells CW, Cooley BC, Desai D, Morateck PA, Gorski J, Montgomery RR) J Clin Invest 2006 Jul;116(7):1974-82 158 Citations |
| 1 | Myc translocations in B cell and plasma cell neoplasms. (Janz S) DNA Repair (Amst) 2006 Sep 08;5(9-10):1213-24 86 Citations |
| 1 | Sample-specific diamagnetic and paramagnetic passive shimming. (Koch KM, Brown PB, Rothman DL, de Graaf RA) J Magn Reson 2006 Sep;182(1):66-74 49 Citations |
| 1 | Conditional gene expression in the mouse using a Sleeping Beauty gene-trap transposon. (Geurts AM, Wilber A, Carlson CM, Lobitz PD, Clark KJ, Hackett PB, McIvor RS, Largaespada DA) BMC Biotechnol 2006 Jun 26;6:30 36 Citations |
| 1 | Identification of a TLR-independent pathway for Borrelia burgdorferi-induced expression of matrix metalloproteinases and inflammatory mediators through binding to integrin alpha 3 beta 1. (Behera AK, Hildebrand E, Uematsu S, Akira S, Coburn J, Hu LT) J Immunol 2006 Jul 01;177(1):657-64 63 Citations |
| 1 | Role of immune cells in animal models for inherited peripheral neuropathies. (Wang Ip C, Kroner A, Fischer S, Berghoff M, Kobsar I, Mäurer M, Martini R) Neuromolecular Med 2006;8(1-2):175-90 41 Citations |
| 1 | A method for single-session cocaine self-administration in the mouse. (Olsen CM, Winder DG) Psychopharmacology (Berl) 2006 Jul;187(1):13-21 12 Citations |
| 1 | Post-training estrogen enhances spatial and object memory consolidation in female mice. (Gresack JE, Frick KM) Pharmacol Biochem Behav 2006 May;84(1):112-9 129 Citations |
| 1 | CDDO-Imidazolide inhibits growth and survival of c-Myc-induced mouse B cell and plasma cell neoplasms. (Han SS, Peng L, Chung ST, DuBois W, Maeng SH, Shaffer AL, Sporn MB, Janz S) Mol Cancer 2006 Jun 07;5:22 15 Citations |
| 1 | Soluble endoglin contributes to the pathogenesis of preeclampsia. (Venkatesha S, Toporsian M, Lam C, Hanai J, Mammoto T, Kim YM, Bdolah Y, Lim KH, Yuan HT, Libermann TA, Stillman IE, Roberts D, D'Amore PA, Epstein FH, Sellke FW, Romero R, Sukhatme VP, Letarte M, Karumanchi SA) Nat Med 2006 Jun;12(6):642-9 1588 Citations |
| 1 | Opposing effects of ICOS on graft-versus-host disease mediated by CD4 and CD8 T cells. (Yu XZ, Liang Y, Nurieva RI, Guo F, Anasetti C, Dong C) J Immunol 2006 Jun 15;176(12):7394-401 43 Citations |
| 1 | Suz12 binds to silenced regions of the genome in a cell-type-specific manner. (Squazzo SL, O'Geen H, Komashko VM, Krig SR, Jin VX, Jang SW, Margueron R, Reinberg D, Green R, Farnham PJ) Genome Res 2006 Jul;16(7):890-900 275 Citations |
| 1 | The balancing act: inhibitory Ly49 regulate NKG2D-mediated NK cell functions. (Malarkannan S) Semin Immunol 2006 Jun;18(3):186-92 22 Citations |
| 1 | T-cell tolerance or function is determined by combinatorial costimulatory signals. (Nurieva R, Thomas S, Nguyen T, Martin-Orozco N, Wang Y, Kaja MK, Yu XZ, Dong C) EMBO J 2006 Jun 07;25(11):2623-33 206 Citations |
| 1 | Structure-based prediction of insertion-site preferences of transposons into chromosomes. (Geurts AM, Hackett CS, Bell JB, Bergemann TL, Collier LS, Carlson CM, Largaespada DA, Hackett PB) Nucleic Acids Res 2006;34(9):2803-11 65 Citations |
| 1 | Collagenase-2 and -3 mediate epidermal growth factor receptor transactivation by bradykinin B2 receptor in kidney cells. (Mukhin YV, Gooz M, Raymond JR, Garnovskaya MN) J Pharmacol Exp Ther 2006 Sep;318(3):1033-43 18 Citations |
| 1 | Functional expression of mouse relaxin and mouse relaxin-3 in the lung from an Ebola virus glycoprotein-pseudotyped lentivirus via tracheal delivery. (Silvertown JD, Walia JS, Summerlee AJ, Medin JA) Endocrinology 2006 Aug;147(8):3797-808 24 Citations |
| 3 | Clinical and experimental applications of NIR-LED photobiomodulation. (Desmet KD, Paz DA, Corry JJ, Eells JT, Wong-Riley MT, Henry MM, Buchmann EV, Connelly MP, Dovi JV, Liang HL, Henshel DS, Yeager RL, Millsap DS, Lim J, Gould LJ, Das R, Jett M, Hodgson BD, Margolis D, Whelan HT) Photomed Laser Surg 2006 Apr;24(2):121-8 311 Citations |
| 1 | Deglycosylated anti-amyloid-beta antibodies eliminate cognitive deficits and reduce parenchymal amyloid with minimal vascular consequences in aged amyloid precursor protein transgenic mice. (Wilcock DM, Alamed J, Gottschall PE, Grimm J, Rosenthal A, Pons J, Ronan V, Symmonds K, Gordon MN, Morgan D) J Neurosci 2006 May 17;26(20):5340-6 148 Citations |
| 1 | Steroid and xenobiotic receptor and vitamin D receptor crosstalk mediates CYP24 expression and drug-induced osteomalacia. (Zhou C, Assem M, Tay JC, Watkins PB, Blumberg B, Schuetz EG, Thummel KE) J Clin Invest 2006 Jun;116(6):1703-12 227 Citations |
| 1 | CRYAB and HSPB2 deficiency increases myocyte mitochondrial permeability transition and mitochondrial calcium uptake. (Kadono T, Zhang XQ, Srinivasan S, Ishida H, Barry WH, Benjamin IJ) J Mol Cell Cardiol 2006 Jun;40(6):783-9 51 Citations |
| 2 | Inhibition of an equilibrative nucleoside transporter by cannabidiol: a mechanism of cannabinoid immunosuppression. (Carrier EJ, Auchampach JA, Hillard CJ) Proc Natl Acad Sci U S A 2006 May 16;103(20):7895-900 402 Citations |
| 1 | Lymphoblastic leukemia/lymphoma in mice overexpressing the Mer (MerTK) receptor tyrosine kinase. (Keating AK, Salzberg DB, Sather S, Liang X, Nickoloff S, Anwar A, Deryckere D, Hill K, Joung D, Sawczyn KK, Park J, Curran-Everett D, McGavran L, Meltesen L, Gore L, Johnson GL, Graham DK) Oncogene 2006 Oct 05;25(45):6092-100 83 Citations |
| 1 | The use of the Dhcr7 knockout mouse to accurately determine the origin of fetal sterols. (Tint GS, Yu H, Shang Q, Xu G, Patel SB) J Lipid Res 2006 Jul;47(7):1535-41 87 Citations |
| 1 | Extracellular matrix remodeling and organization in developing and diseased aortic valves. (Hinton RB Jr, Lincoln J, Deutsch GH, Osinska H, Manning PB, Benson DW, Yutzey KE) Circ Res 2006 Jun 09;98(11):1431-8 372 Citations |
| 1 | Angiotensinogen modulates renal vasculature growth. (Brand M, Lamandé N, Sigmund CD, Larger E, Corvol P, Gasc JM) Hypertension 2006 Jun;47(6):1067-74 15 Citations |
| 1 | Nitric oxide-induced resistance to lethal photooxidative damage in a breast tumor cell line. (Niziolek M, Korytowski W, Girotti AW) Free Radic Biol Med 2006 Apr 15;40(8):1323-31 36 Citations |
| 1 | Scavenger receptor class B Type I (SR-BI) assembles into detergent-sensitive dimers and tetramers. (Sahoo D, Darlington YF, Pop D, Williams DL, Connelly MA) Biochim Biophys Acta 2007 Jul;1771(7):807-17 41 Citations |
| 1 | Effects of estrogen and progesterone on spatial memory consolidation in aged females. (Harburger LL, Bennett JC, Frick KM) Neurobiol Aging 2007 Apr;28(4):602-10 81 Citations |
| 1 | Heat shock response: lessons from mouse knockouts. (Christians ES, Benjamin IJ) Handb Exp Pharmacol 2006(172):139-52 27 Citations |
| 1 | Dual role of the exocyst in AMPA receptor targeting and insertion into the postsynaptic membrane. (Gerges NZ, Backos DS, Rupasinghe CN, Spaller MR, Esteban JA) EMBO J 2006 Apr 19;25(8):1623-34 118 Citations |
| 1 | Early transposable element insertion in intron 9 of the Hsf4 gene results in autosomal recessive cataracts in lop11 and ldis1 mice. (Talamas E, Jackson L, Koeberl M, Jackson T, McElwee JL, Hawes NL, Chang B, Jablonski MM, Sidjanin DJ) Genomics 2006 Jul;88(1):44-51 21 Citations |
| 1 | Targeted disruption of CD38 accelerates autoimmune diabetes in NOD/Lt mice by enhancing autoimmunity in an ADP-ribosyltransferase 2-dependent fashion. (Chen J, Chen YG, Reifsnyder PC, Schott WH, Lee CH, Osborne M, Scheuplein F, Haag F, Koch-Nolte F, Serreze DV, Leiter EH) J Immunol 2006 Apr 15;176(8):4590-9 54 Citations |
| 1 | Mice heterozygous for beta-ENaC deletion have defective potassium excretion. (Cao XR, Shi PP, Sigmund RD, Husted RF, Sigmund CD, Williamson RA, Stokes JB, Yang B) Am J Physiol Renal Physiol 2006 Jul;291(1):F107-15 14 Citations |
| 1 | Proteasome-dependent down-regulation of activated Stat5A in the nucleus. (Chen Y, Dai X, Haas AL, Wen R, Wang D) Blood 2006 Jul 15;108(2):566-74 24 Citations |
| 1 | Pharmacological evaluation of cannabinoid receptor ligands in a mouse model of anxiety: further evidence for an anxiolytic role for endogenous cannabinoid signaling. (Patel S, Hillard CJ) J Pharmacol Exp Ther 2006 Jul;318(1):304-11 345 Citations |
| 1 | Silencing of epithelial CXCL12 expression by DNA hypermethylation promotes colonic carcinoma metastasis. (Wendt MK, Johanesen PA, Kang-Decker N, Binion DG, Shah V, Dwinell MB) Oncogene 2006 Aug 17;25(36):4986-97 130 Citations |
| 1 | Vascular endothelial growth factor and hepatocyte regeneration in acetaminophen toxicity. (Donahower B, McCullough SS, Kurten R, Lamps LW, Simpson P, Hinson JA, James LP) Am J Physiol Gastrointest Liver Physiol 2006 Jul;291(1):G102-9 70 Citations |
| 1 | Extracellular-signal regulated kinase 1-dependent metabotropic glutamate receptor 5-induced long-term depression in the bed nucleus of the stria terminalis is disrupted by cocaine administration. (Grueter BA, Gosnell HB, Olsen CM, Schramm-Sapyta NL, Nekrasova T, Landreth GE, Winder DG) J Neurosci 2006 Mar 22;26(12):3210-9 100 Citations |
| 1 | Piper longum inhibits VEGF and proinflammatory cytokines and tumor-induced angiogenesis in C57BL/6 mice. (Sunila ES, Kuttan G) Int Immunopharmacol 2006 May;6(5):733-41 39 Citations |
| 1 | Graft-versus-leukemia and graft-versus-host reactions after donor lymphocyte infusion are initiated by host-type antigen-presenting cells and regulated by regulatory T cells in early and long-term chimeras. (Xia G, Truitt RL, Johnson BD) Biol Blood Marrow Transplant 2006 Apr;12(4):397-407 57 Citations |
| 1 | Upregulation of immunoproteasomes by nitric oxide: potential antioxidative mechanism in endothelial cells. (Kotamraju S, Matalon S, Matsunaga T, Shang T, Hickman-Davis JM, Kalyanaraman B) Free Radic Biol Med 2006 Mar 15;40(6):1034-44 88 Citations |
| 1 | RAS blockade decreases blood pressure and proteinuria in transgenic mice overexpressing rat angiotensinogen gene in the kidney. (Sachetelli S, Liu Q, Zhang SL, Liu F, Hsieh TJ, Brezniceanu ML, Guo DF, Filep JG, Ingelfinger JR, Sigmund CD, Hamet P, Chan JS) Kidney Int 2006 Mar;69(6):1016-23 114 Citations |
| 1 | Posttranslational, translational, and transcriptional responses to nitric oxide stress in Cryptococcus neoformans: implications for virulence. (Missall TA, Pusateri ME, Donlin MJ, Chambers KT, Corbett JA, Lodge JK) Eukaryot Cell 2006 Mar;5(3):518-29 75 Citations |
| 1 | Tumor-derived macrophage migration inhibitory factor (MIF) inhibits T lymphocyte activation. (Yan X, Orentas RJ, Johnson BD) Cytokine 2006 Feb 21;33(4):188-98 48 Citations |
| 1 | Genome-wide analysis of core promoter elements from conserved human and mouse orthologous pairs. (Jin VX, Singer GA, Agosto-Pérez FJ, Liyanarachchi S, Davuluri RV) BMC Bioinformatics 2006 Mar 07;7:114 62 Citations |
| 1 | Alloantigen affinity and CD4 help determine severity of graft-versus-host disease mediated by CD8 donor T cells. (Yu XZ, Albert MH, Anasetti C) J Immunol 2006 Mar 15;176(6):3383-90 23 Citations |
| 1 | In vivo Himar1-based transposon mutagenesis of Francisella tularensis. (Maier TM, Pechous R, Casey M, Zahrt TC, Frank DW) Appl Environ Microbiol 2006 Mar;72(3):1878-85 75 Citations |
| 1 | Plasma cell tumour progression in iMycEmu gene-insertion mice. (Kim JS, Han SS, Park SS, McNeil N, Janz S) J Pathol 2006 May;209(1):44-55 10 Citations |
| 1 | Strategies for delaying or treating in vivo acquired resistance to trastuzumab in human breast cancer xenografts. (du Manoir JM, Francia G, Man S, Mossoba M, Medin JA, Viloria-Petit A, Hicklin DJ, Emmenegger U, Kerbel RS) Clin Cancer Res 2006 Feb 01;12(3 Pt 1):904-16 129 Citations |
| 1 | Stem cell factor receptor induces progenitor and natural killer cell-mediated cardiac survival and repair after myocardial infarction. (Ayach BB, Yoshimitsu M, Dawood F, Sun M, Arab S, Chen M, Higuchi K, Siatskas C, Lee P, Lim H, Zhang J, Cukerman E, Stanford WL, Medin JA, Liu PP) Proc Natl Acad Sci U S A 2006 Feb 14;103(7):2304-9 107 Citations |
| 1 | Attenuated demyelination in the absence of the macrophage-restricted adhesion molecule sialoadhesin (Siglec-1) in mice heterozygously deficient in P0. (Kobsar I, Oetke C, Kroner A, Wessig C, Crocker P, Martini R) Mol Cell Neurosci 2006 Apr;31(4):685-91 37 Citations |
| 1 | Nonalcoholic Fatty gallbladder disease: the influence of diet in lean and obese mice. (Goldblatt MI, Swartz-Basile DA, Al-Azzawi HH, Tran KQ, Nakeeb A, Pitt HA) J Gastrointest Surg 2006 Feb;10(2):193-201 24 Citations |
| 1 | Renal thrombotic microangiopathy in a genetic model of hypertension in mice. (Sethi S, Iida S, Sigmund CD, Heistad DD) Exp Biol Med (Maywood) 2006 Feb;231(2):196-203 9 Citations |
| 1 | Evidence supporting a functional role for intracellular renin in the brain. (Lavoie JL, Liu X, Bianco RA, Beltz TG, Johnson AK, Sigmund CD) Hypertension 2006 Mar;47(3):461-6 68 Citations |
| 1 | AMD3100 mobilizes hematopoietic stem cells with long-term repopulating capacity in nonhuman primates. (Larochelle A, Krouse A, Metzger M, Orlic D, Donahue RE, Fricker S, Bridger G, Dunbar CE, Hematti P) Blood 2006 May 01;107(9):3772-8 176 Citations |
| 1 | A murine model of invasive aspergillosis: variable benefit of interferon-gamma administration under in vitro and in vivo conditions. (Johnson CP, Edmiston CE Jr, Zhu YR, Adams MB, Roza AM, Kurup V) Surg Infect (Larchmt) 2005;6(4):397-407 4 Citations |
| 1 | Inactivation of NADPH oxidase organizer 1 results in severe imbalance. (Kiss PJ, Knisz J, Zhang Y, Baltrusaitis J, Sigmund CD, Thalmann R, Smith RJ, Verpy E, Bánfi B) Curr Biol 2006 Jan 24;16(2):208-13 91 Citations |
| 1 | Importance of heat-labile enterotoxin in colonization of the adult mouse small intestine by human enterotoxigenic Escherichia coli strains. (Allen KP, Randolph MM, Fleckenstein JM) Infect Immun 2006 Feb;74(2):869-75 112 Citations |
| 1 | Excess circulating angiopoietin-2 may contribute to pulmonary vascular leak in sepsis in humans. (Parikh SM, Mammoto T, Schultz A, Yuan HT, Christiani D, Karumanchi SA, Sukhatme VP) PLoS Med 2006 Mar;3(3):e46 454 Citations |
| 1 | CD200, a "no danger" signal for hair follicles. (Rosenblum MD, Yancey KB, Olasz EB, Truitt RL) J Dermatol Sci 2006 Mar;41(3):165-74 68 Citations |
| 1 | MPromDb: an integrated resource for annotation and visualization of mammalian gene promoters and ChIP-chip experimental data. (Sun H, Palaniswamy SK, Pohar TT, Jin VX, Huang TH, Davuluri RV) Nucleic Acids Res 2006 Jan 01;34(Database issue):D98-103 35 Citations |
| 1 | Novel leptin receptor mutation in NOD/LtJ mice suppresses type 1 diabetes progression: II. Immunologic analysis. (Lee CH, Chen YG, Chen J, Reifsnyder PC, Serreze DV, Clare-Salzler M, Rodriguez M, Wasserfall C, Atkinson MA, Leiter EH) Diabetes 2006 Jan;55(1):171-8 29 Citations |
| 2 | Fetomaternal cross talk in the placental vascular bed: control of coagulation by trophoblast cells. (Sood R, Kalloway S, Mast AE, Hillard CJ, Weiler H) Blood 2006 Apr 15;107(8):3173-80 89 Citations |
| 1 | Role of the serum response factor in regulating contractile apparatus gene expression and sarcomeric integrity in cardiomyocytes. (Balza RO Jr, Misra RP) J Biol Chem 2006 Mar 10;281(10):6498-510 86 Citations |
| 1 | RANK ligand expression in heat shock factor-2 deficient mouse bone marrow stromal/preosteoblast cells. (Kajiya H, Ito M, Ohshima H, Kenmotsu S, Ries WL, Benjamin IJ, Reddy SV) J Cell Biochem 2006 Apr 15;97(6):1362-9 10 Citations |
| 1 | Sleeping Beauty-mediated transposition and long-term expression in vivo: use of the LoxP/Cre recombinase system to distinguish transposition-specific expression. (Score PR, Belur LR, Frandsen JL, Geurts JL, Yamaguchi T, Somia NV, Hackett PB, Largaespada DA, McIvor RS) Mol Ther 2006 Mar;13(3):617-24 27 Citations |
| 1 | Distinct roles of phosphoinositide-3 kinase and phospholipase Cgamma2 in B-cell receptor-mediated signal transduction. (Dai X, Chen Y, Schuman J, Hua Z, Adamson JW, Wen R, Wang D) Mol Cell Biol 2006 Jan;26(1):88-99 12 Citations |
| 1 | A murine world without HSFs: meeting report. (Christians E, Benjamin IJ) Cell Stress Chaperones 2005;10(4):265-7 1 Citation |
| 2 | Adenosine inhibits tumor necrosis factor-alpha release from mouse peritoneal macrophages via A2A and A2B but not the A3 adenosine receptor. (Kreckler LM, Wan TC, Ge ZD, Auchampach JA) J Pharmacol Exp Ther 2006 Apr;317(1):172-80 176 Citations |
| 1 | Reduced Paneth cell alpha-defensins in ileal Crohn's disease. (Wehkamp J, Salzman NH, Porter E, Nuding S, Weichenthal M, Petras RE, Shen B, Schaeffeler E, Schwab M, Linzmeier R, Feathers RW, Chu H, Lima H Jr, Fellermann K, Ganz T, Stange EF, Bevins CL) Proc Natl Acad Sci U S A 2005 Dec 13;102(50):18129-34 857 Citations |
| 1 | Adenovirus serotype 5 E1A sensitizes tumor cells to NKG2D-dependent NK cell lysis and tumor rejection. (Routes JM, Ryan S, Morris K, Takaki R, Cerwenka A, Lanier LL) J Exp Med 2005 Dec 05;202(11):1477-82 66 Citations |
| 1 | Unraveling Brucella genomics and pathogenesis in immunocompromised IRF-1-/- mice. (Rajashekara G, Krepps M, Eskra L, Mathison A, Montgomery A, Ishii Y, Splitter G) Am J Reprod Immunol 2005 Dec;54(6):358-68 16 Citations |
| 1 | Detecting axon damage in spinal cord from a mouse model of multiple sclerosis. (Kim JH, Budde MD, Liang HF, Klein RS, Russell JH, Cross AH, Song SK) Neurobiol Dis 2006 Mar;21(3):626-32 212 Citations |
| 1 | Correlation of gene and protein structures in the FXYD family proteins. (Franzin CM, Yu J, Thai K, Choi J, Marassi FM) J Mol Biol 2005 Dec 09;354(4):743-50 14 Citations |
| 1 | Murine gammaherpesvirus 68 infection is associated with lymphoproliferative disease and lymphoma in BALB beta2 microglobulin-deficient mice. (Tarakanova VL, Suarez F, Tibbetts SA, Jacoby MA, Weck KE, Hess JL, Speck SH, Virgin HW 4th) J Virol 2005 Dec;79(23):14668-79 98 Citations |
| 1 | Protective effect of Thuja occidentalis against radiation-induced toxicity in mice. (Sunila ES, Kuttan G) Integr Cancer Ther 2005 Dec;4(4):322-8 16 Citations |
| 1 | Molecular and cytological features of the mouse B-cell lymphoma line iMycEmu-1. (Han SS, Shaffer AL, Peng L, Chung ST, Lim JH, Maeng S, Kim JS, McNeil N, Ried T, Staudt LM, Janz S) Mol Cancer 2005 Nov 09;4:40 6 Citations |
| 1 | Allergic dysregulation and hyperimmunoglobulinemia E in Foxp3 mutant mice. (Lin W, Truong N, Grossman WJ, Haribhai D, Williams CB, Wang J, Martín MG, Chatila TA) J Allergy Clin Immunol 2005 Nov;116(5):1106-15 217 Citations |
| 1 | A murine model of deep vein thrombosis: characterization and validation in transgenic mice. (Cooley BC, Szema L, Chen CY, Schwab JP, Schmeling G) Thromb Haemost 2005 Sep;94(3):498-503 39 Citations |
| 1 | Activity of irinotecan and the tyrosine kinase inhibitor CEP-751 in medullary thyroid cancer. (Strock CJ, Park JI, Rosen DM, Ruggeri B, Denmeade SR, Ball DW, Nelkin BD) J Clin Endocrinol Metab 2006 Jan;91(1):79-84 44 Citations |
| 1 | Peroxisome proliferator-activated receptor-gamma and its agonists in hypertension and atherosclerosis : mechanisms and clinical implications. (Halabi CM, Sigmund CD) Am J Cardiovasc Drugs 2005;5(6):389-98 18 Citations |
| 1 | Long-term continuous, but not daily, environmental enrichment reduces spatial memory decline in aged male mice. (Bennett JC, McRae PA, Levy LJ, Frick KM) Neurobiol Learn Mem 2006 Mar;85(2):139-52 153 Citations |
| 1 | Arp2/3 complex-deficient mouse fibroblasts are viable and have normal leading-edge actin structure and function. (Di Nardo A, Cicchetti G, Falet H, Hartwig JH, Stossel TP, Kwiatkowski DJ) Proc Natl Acad Sci U S A 2005 Nov 08;102(45):16263-8 50 Citations |
| 1 | Transgenic expression of a dominant-negative ASIC3 subunit leads to increased sensitivity to mechanical and inflammatory stimuli. (Mogil JS, Breese NM, Witty MF, Ritchie J, Rainville ML, Ase A, Abbadi N, Stucky CL, Séguéla P) J Neurosci 2005 Oct 26;25(43):9893-901 112 Citations |
| 1 | Protective effect of Piper longum fruit ethanolic extract on radiation induced damages in mice: a preliminary study. (Sunila ES, Kuttan G) Fitoterapia 2005 Dec;76(7-8):649-55 34 Citations |
| 1 | The costimulatory molecules CD80, CD86 and OX40L are up-regulated in Aspergillus fumigatus sensitized mice. (Barrios CS, Johnson BD, D Henderson J Jr, Fink JN, Kelly KJ, Kurup VP) Clin Exp Immunol 2005 Nov;142(2):242-50 17 Citations |
| 1 | Erythrocyte adhesion is modified by alterations in cellular tonicity and volume. (Wandersee NJ, Punzalan RC, Rettig MP, Kennedy MD, Pajewski NM, Sabina RL, Paul Scott J, Low PS, Hillery CA) Br J Haematol 2005 Nov;131(3):366-77 24 Citations |
| 1 | The tumour necrosis factor-alpha inhibitor adalimumab rapidly reverses the decrease in epidermal Langerhans cell density in psoriatic plaques. (Gordon KB, Bonish BK, Patel T, Leonardi CL, Nickoloff BJ) Br J Dermatol 2005 Nov;153(5):945-53 59 Citations |
| 3 | Effects of D-4F on vasodilation and vessel wall thickness in hypercholesterolemic LDL receptor-null and LDL receptor/apolipoprotein A-I double-knockout mice on Western diet. (Ou J, Wang J, Xu H, Ou Z, Sorci-Thomas MG, Jones DW, Signorino P, Densmore JC, Kaul S, Oldham KT, Pritchard KA Jr) Circ Res 2005 Nov 25;97(11):1190-7 112 Citations |
| 1 | Differentiation of murine embryonic stem cells induces progesterone receptor gene expression. (Sauter CN, McDermid RL, Weinberg AL, Greco TL, Xu X, Murdoch FE, Fritsch MK) Exp Cell Res 2005 Dec 10;311(2):251-64 29 Citations |
| 1 | ERTargetDB: an integral information resource of transcription regulation of estrogen receptor target genes. (Jin VX, Sun H, Pohar TT, Liyanarachchi S, Palaniswamy SK, Huang TH, Davuluri RV) J Mol Endocrinol 2005 Oct;35(2):225-30 26 Citations |
| 2 | 1H, 15N and 13C resonance assignments of the heme-binding protein murine p22HBP. (Dias JS, Macedo AL, Ferreira GC, Jeanty N, Taketani S, Goodfellow BJ, Peterson FC, Volkman BF) J Biomol NMR 2005 Aug;32(4):338 4 Citations |
| 1 | Angiostatin. (Doll JA, Soff GA) Cancer Treat Res 2005;126:175-204 12 Citations |
| 1 | Recent insights into the Smith-Lemli-Opitz syndrome. (Yu H, Patel SB) Clin Genet 2005 Nov;68(5):383-91 77 Citations |
| 1 | Cocaine self-administration reduces excitatory responses in the mouse nucleus accumbens shell. (Schramm-Sapyta NL, Olsen CM, Winder DG) Neuropsychopharmacology 2006 Jul;31(7):1444-51 48 Citations |
| 1 | Improved excitation light rejection enhances small-animal fluorescent optical imaging. (Hwang K, Houston JP, Rasmussen JC, Joshi A, Ke S, Li C, Sevick-Muraca EM) Mol Imaging 2005;4(3):194-204 35 Citations |
| 1 | Expression of matrix metalloproteinases subsequent to urogenital Chlamydia muridarum infection of mice. (Ramsey KH, Sigar IM, Schripsema JH, Shaba N, Cohoon KP) Infect Immun 2005 Oct;73(10):6962-73 57 Citations |
| 1 | Characterization of the antibody response to the receptor binding domain of botulinum neurotoxin serotypes A and E. (Baldwin MR, Tepp WH, Pier CL, Bradshaw M, Ho M, Wilson BA, Fritz RB, Johnson EA, Barbieri JT) Infect Immun 2005 Oct;73(10):6998-7005 58 Citations |
| 2 | NF-kappaB as a target for the prevention of graft-versus-host disease: comparative efficacy of bortezomib and PS-1145. (Vodanovic-Jankovic S, Hari P, Jacobs P, Komorowski R, Drobyski WR) Blood 2006 Jan 15;107(2):827-34 108 Citations |
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| 2 | Platelet PECAM-1 inhibits thrombus formation in vivo. (Falati S, Patil S, Gross PL, Stapleton M, Merrill-Skoloff G, Barrett NE, Pixton KL, Weiler H, Cooley B, Newman DK, Newman PJ, Furie BC, Furie B, Gibbins JM) Blood 2006 Jan 15;107(2):535-41 184 Citations |
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| 1 | Of mice and men: use of animal models to identify possible interventions for the prevention of autoimmune type 1 diabetes in humans. (Serreze DV, Chen YG) Trends Immunol 2005 Nov;26(11):603-7 21 Citations |
| 1 | Targeting of urokinase plasminogen activator receptor in human pancreatic carcinoma cells inhibits c-Met- and insulin-like growth factor-I receptor-mediated migration and invasion and orthotopic tumor growth in mice. (Bauer TW, Liu W, Fan F, Camp ER, Yang A, Somcio RJ, Bucana CD, Callahan J, Parry GC, Evans DB, Boyd DD, Mazar AP, Ellis LM) Cancer Res 2005 Sep 01;65(17):7775-81 136 Citations |
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| 1 | Neuroblastoma cells transiently transfected to simultaneously express the co-stimulatory molecules CD54, CD80, CD86, and CD137L generate antitumor immunity in mice. (Johnson BD, Gershan JA, Natalia N, Zujewski H, Weber JJ, Yan X, Orentas RJ) J Immunother 2005;28(5):449-60 32 Citations |
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| 1 | Armed CD4+ Th1 effector cells and activated macrophages participate in bile duct injury in murine biliary atresia. (Mack CL, Tucker RM, Sokol RJ, Kotzin BL) Clin Immunol 2005 May;115(2):200-9 96 Citations |
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| 1 | Neuropilin-1 suppresses tumorigenic properties in a human pancreatic adenocarcinoma cell line lacking neuropilin-1 coreceptors. (Gray MJ, Wey JS, Belcheva A, McCarty MF, Trevino JG, Evans DB, Ellis LM, Gallick GE) Cancer Res 2005 May 01;65(9):3664-70 83 Citations |
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| 1 | Ssdp1 regulates head morphogenesis of mouse embryos by activating the Lim1-Ldb1 complex. (Nishioka N, Nagano S, Nakayama R, Kiyonari H, Ijiri T, Taniguchi K, Shawlot W, Hayashizaki Y, Westphal H, Behringer RR, Matsuda Y, Sakoda S, Kondoh H, Sasaki H) Development 2005 Jun;132(11):2535-46 60 Citations |
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| 1 | Calcium-stimulated adenylyl cyclases modulate ethanol-induced neurodegeneration in the neonatal brain. (Maas JW Jr, Indacochea RA, Muglia LM, Tran TT, Vogt SK, West T, Benz A, Shute AA, Holtzman DM, Mennerick S, Olney JW, Muglia LJ) J Neurosci 2005 Mar 02;25(9):2376-85 40 Citations |
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| 1 | Distinct stress responses of two functional laccases in Cryptococcus neoformans are revealed in the absence of the thiol-specific antioxidant Tsa1. (Missall TA, Moran JM, Corbett JA, Lodge JK) Eukaryot Cell 2005 Jan;4(1):202-8 98 Citations |
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| 1 | Serum response factor, an enriched cardiac mesoderm obligatory factor, is a downstream gene target for Tbx genes. (Barron MR, Belaguli NS, Zhang SX, Trinh M, Iyer D, Merlo X, Lough JW, Parmacek MS, Bruneau BG, Schwartz RJ) J Biol Chem 2005 Mar 25;280(12):11816-28 41 Citations |
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| 1 | The postmortal accumulation of brain N-arachidonylethanolamine (anandamide) is dependent upon fatty acid amide hydrolase activity. (Patel S, Carrier EJ, Ho WS, Rademacher DJ, Cunningham S, Reddy DS, Falck JR, Cravatt BF, Hillard CJ) J Lipid Res 2005 Feb;46(2):342-9 118 Citations |
| 1 | GDNF-induced leukemia inhibitory factor can mediate differentiation via the MEK/ERK pathway in pheochromocytoma cells derived from nf1-heterozygous knockout mice. (Park JI, Powers JF, Tischler AS, Strock CJ, Ball DW, Nelkin BD) Exp Cell Res 2005 Feb 01;303(1):79-88 16 Citations |
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| 1 | A NotI-EcoRV promoter library for studies of genetic and epigenetic alterations in mouse models of human malignancies. (Yu L, Liu C, Bennett K, Wu YZ, Dai Z, Vandeusen J, Opavsky R, Raval A, Trikha P, Rodriguez B, Becknell B, Mao C, Lee S, Davuluri RV, Leone G, Van den Veyver IB, Caligiuri MA, Plass C) Genomics 2004 Oct;84(4):647-60 22 Citations |
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| 1 | Prevention of lethal acute GVHD with an agonistic CD28 antibody and rapamycin. (Albert MH, Yu XZ, Martin PJ, Anasetti C) Blood 2005 Feb 01;105(3):1355-61 20 Citations |
| 1 | Sterol carrier protein-2-facilitated intermembrane transfer of cholesterol- and phospholipid-derived hydroperoxides. (Vila A, Levchenko VV, Korytowski W, Girotti AW) Biochemistry 2004 Oct 05;43(39):12592-605 46 Citations |
| 1 | Nuclear localization of angiotensinogen in astrocytes. (Sherrod M, Liu X, Zhang X, Sigmund CD) Am J Physiol Regul Integr Comp Physiol 2005 Feb;288(2):R539-46 55 Citations |
| 1 | Structure of cerebral arterioles in mice deficient in expression of the gene for endothelial nitric oxide synthase. (Baumbach GL, Sigmund CD, Faraci FM) Circ Res 2004 Oct 15;95(8):822-9 64 Citations |
| 1 | Environmental enrichment reduces the mnemonic and neural benefits of estrogen. (Gresack JE, Frick KM) Neuroscience 2004;128(3):459-71 73 Citations |
| 1 | Calcium-dependent dephosphorylation mediates the hyperosmotic and lysophosphatidic acid-dependent inhibition of natriuretic peptide receptor-B/guanylyl cyclase-B. (Potthast R, Abbey-Hosch SE, Antos LK, Marchant JS, Kuhn M, Potter LR) J Biol Chem 2004 Nov 19;279(47):48513-9 33 Citations |
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| 2 | Endocannabinoid signaling negatively modulates stress-induced activation of the hypothalamic-pituitary-adrenal axis. (Patel S, Roelke CT, Rademacher DJ, Cullinan WE, Hillard CJ) Endocrinology 2004 Dec;145(12):5431-8 416 Citations |
| 3 | Alpha phenyl-tert-butyl nitrone (PBN) protects syngeneic marrow transplant recipients from the lethal cytokine syndrome occurring after agonistic CD40 antibody administration. (Gendelman M, Halligan N, Komorowski R, Logan B, Murphy WJ, Blazar BR, Pritchard KA Jr, Drobyski WR) Blood 2005 Jan 01;105(1):428-31 10 Citations |
| 2 | Phospholipase Cgamma2 contributes to stable thrombus formation on VWF. (Rathore V, Wang D, Newman DK, Newman PJ) FEBS Lett 2004 Aug 27;573(1-3):26-30 14 Citations |
| 1 | NKG2D receptor-mediated NK cell function is regulated by inhibitory Ly49 receptors. (Regunathan J, Chen Y, Wang D, Malarkannan S) Blood 2005 Jan 01;105(1):233-40 54 Citations |
| 1 | Renal phenotype is exacerbated in Os and lpr double mutant mice. (Jarad G, Lakhe-Reddy S, Blatnik J, Koepke M, Khan S, El-Meanawy MA, O'Connor AS, Sedor JR, Schelling JR) Kidney Int 2004 Sep;66(3):1029-35 6 Citations |
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| 1 | Expression of the cytoplasmic tail of LMP1 in mice induces hyperactivation of B lymphocytes and disordered lymphoid architecture. (Stunz LL, Busch LK, Munroe ME, Sigmund CD, Tygrett LT, Waldschmidt TJ, Bishop GA) Immunity 2004 Aug;21(2):255-66 53 Citations |
| 1 | Efficient DNA cassette exchange in mouse embryonic stem cells by staggered positive-negative selection. (Long Q, Shelton KD, Lindner J, Jones JR, Magnuson MA) Genesis 2004 Aug;39(4):256-62 19 Citations |
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| 1 | Synergistic interactions between cannabinoids and environmental stress in the activation of the central amygdala. (Patel S, Cravatt BF, Hillard CJ) Neuropsychopharmacology 2005 Mar;30(3):497-507 138 Citations |
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| 1 | Characterization of Lef-1 promoter segments that facilitate inductive developmental expression in skin. (Liu X, Driskell RR, Luo M, Abbott D, Filali M, Cheng N, Sigmund CD, Engelhardt JF) J Invest Dermatol 2004 Aug;123(2):264-74 29 Citations |
| 1 | Differential expression of granzymes A and B in human cytotoxic lymphocyte subsets and T regulatory cells. (Grossman WJ, Verbsky JW, Tollefsen BL, Kemper C, Atkinson JP, Ley TJ) Blood 2004 Nov 01;104(9):2840-8 423 Citations |
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| 1 | Novel targeted deregulation of c-Myc cooperates with Bcl-X(L) to cause plasma cell neoplasms in mice. (Cheung WC, Kim JS, Linden M, Peng L, Van Ness B, Polakiewicz RD, Janz S) J Clin Invest 2004 Jun;113(12):1763-73 95 Citations |
| 1 | Wnt-responsive element controls Lef-1 promoter expression during submucosal gland morphogenesis. (Driskell RR, Liu X, Luo M, Filali M, Zhou W, Abbott D, Cheng N, Moothart C, Sigmund CD, Engelhardt JF) Am J Physiol Lung Cell Mol Physiol 2004 Oct;287(4):L752-63 32 Citations |
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| 1 | CD28 ligation induces transplantation tolerance by IFN-gamma-dependent depletion of T cells that recognize alloantigens. (Yu XZ, Albert MH, Martin PJ, Anasetti C) J Clin Invest 2004 Jun;113(11):1624-30 57 Citations |
| 1 | Glucose regulation of insulin gene expression requires the recruitment of p300 by the beta-cell-specific transcription factor Pdx-1. (Mosley AL, Corbett JA, Ozcan S) Mol Endocrinol 2004 Sep;18(9):2279-90 103 Citations |
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| 1 | EGF-related growth factors in the pathogenesis of murine ARPKD. (MacRae Dell K, Nemo R, Sweeney WE Jr, Avner ED) Kidney Int 2004 Jun;65(6):2018-29 50 Citations |
| 1 | Perturbed IFN-gamma-Jak-signal transducers and activators of transcription signaling in tuberous sclerosis mouse models: synergistic effects of rapamycin-IFN-gamma treatment. (El-Hashemite N, Zhang H, Walker V, Hoffmeister KM, Kwiatkowski DJ) Cancer Res 2004 May 15;64(10):3436-43 54 Citations |
| 1 | Delayed thrombocytopenia after treatment with abciximab: a distinct clinical entity associated with the immune response to the drug. (Curtis BR, Divgi A, Garritty M, Aster RH) J Thromb Haemost 2004 Jun;2(6):985-92 77 Citations |
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| 1 | Murine CD8 lymphocyte expansion in vitro by artificial antigen-presenting cells expressing CD137L (4-1BBL) is superior to CD28, and CD137L expressed on neuroblastoma expands CD8 tumour-reactive effector cells in vivo. (Yan X, Johnson BD, Orentas RJ) Immunology 2004 May;112(1):105-16 30 Citations |
| 1 | Selenium deficiency abrogates inflammation-dependent plasma cell tumors in mice. (Felix K, Gerstmeier S, Kyriakopoulos A, Howard OM, Dong HF, Eckhaus M, Behne D, Bornkamm GW, Janz S) Cancer Res 2004 Apr 15;64(8):2910-7 32 Citations |
| 1 | The P2Y agonist UTP activates cutaneous afferent fibers. (Stucky CL, Medler KA, Molliver DC) Pain 2004 May;109(1-2):36-44 64 Citations |
| 1 | Expression of an E1A/E7 chimeric protein sensitizes tumor cells to killing by activated macrophages but not NK cells. (Miura TA, Li H, Morris K, Ryan S, Hembre K, Cook JL, Routes JM) J Virol 2004 May;78(9):4646-54 7 Citations |
| 1 | Increased blood pressure in transgenic mice expressing both human renin and angiotensinogen in the renal proximal tubule. (Lavoie JL, Lake-Bruse KD, Sigmund CD) Am J Physiol Renal Physiol 2004 May;286(5):F965-71 99 Citations |
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| 1 | Glycine 420 near the C-terminal transmembrane domain of SR-BI is critical for proper delivery and metabolism of high density lipoprotein cholesteryl ester. (Parathath S, Sahoo D, Darlington YF, Peng Y, Collins HL, Rothblat GH, Williams DL, Connelly MA) J Biol Chem 2004 Jun 11;279(24):24976-85 26 Citations |
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| 1 | Gene expression profiling of potential PPARgamma target genes in mouse aorta. (Keen HL, Ryan MJ, Beyer A, Mathur S, Scheetz TE, Gackle BD, Faraci FM, Casavant TL, Sigmund CD) Physiol Genomics 2004 Jun 17;18(1):33-42 44 Citations |
| 1 | Ability of Escherichia coli O157:H7 isolates to colonize the intestinal tract of conventional adult CD1 mice is transient. (Conlan JW, Bardy SL, KuoLee R, Webb A, Perry MB) Can J Microbiol 2001 Jan;47(1):91-5 9 Citations |
| 1 | A mouse model of sitosterolemia: absence of Abcg8/sterolin-2 results in failure to secrete biliary cholesterol. (Klett EL, Lu K, Kosters A, Vink E, Lee MH, Altenburg M, Shefer S, Batta AK, Yu H, Chen J, Klein R, Looije N, Oude-Elferink R, Groen AK, Maeda N, Salen G, Patel SB) BMC Med 2004 Mar 24;2:5 126 Citations |
| 1 | Adjacent expression of renin and angiotensinogen in the rostral ventrolateral medulla using a dual-reporter transgenic model. (Lavoie JL, Cassell MD, Gross KW, Sigmund CD) Hypertension 2004 May;43(5):1116-9 74 Citations |
| 1 | Immunomodulatory and antitumor activity of Piper longum Linn. and piperine. (Sunila ES, Kuttan G) J Ethnopharmacol 2004 Feb;90(2-3):339-46 439 Citations |
| 1 | Late gestational lung hypoplasia in a mouse model of the Smith-Lemli-Opitz syndrome. (Yu H, Wessels A, Chen J, Phelps AL, Oatis J, Tint GS, Patel SB) BMC Dev Biol 2004 Feb 02;4:1 28 Citations |
| 1 | Angiotensin II-induced vascular dysfunction is mediated by the AT1A receptor in mice. (Ryan MJ, Didion SP, Mathur S, Faraci FM, Sigmund CD) Hypertension 2004 May;43(5):1074-9 76 Citations |
| 1 | Interactions between hepatic Mrp4 and Sult2a as revealed by the constitutive androstane receptor and Mrp4 knockout mice. (Assem M, Schuetz EG, Leggas M, Sun D, Yasuda K, Reid G, Zelcer N, Adachi M, Strom S, Evans RM, Moore DD, Borst P, Schuetz JD) J Biol Chem 2004 May 21;279(21):22250-7 219 Citations |
| 1 | Conserved enhancer in the serum response factor promoter controls expression during early coronary vasculogenesis. (Nelson TJ, Duncan SA, Misra RP) Circ Res 2004 Apr 30;94(8):1059-66 17 Citations |
| 1 | Genetic analysis of blood pressure in C3H/HeJ and SWR/J mice. (DiPetrillo K, Tsaih SW, Sheehan S, Johns C, Kelmenson P, Gavras H, Churchill GA, Paigen B) Physiol Genomics 2004 Apr 13;17(2):215-20 48 Citations |
| 1 | Nonopioidergic mechanism mediating morphine-induced antianalgesia in the mouse spinal cord. (Wu HE, Thompson J, Sun HS, Leitermann RJ, Fujimoto JM, Tseng LF) J Pharmacol Exp Ther 2004 Jul;310(1):240-6 26 Citations |
| 1 | Rb regulates proliferation and rod photoreceptor development in the mouse retina. (Zhang J, Gray J, Wu L, Leone G, Rowan S, Cepko CL, Zhu X, Craft CM, Dyer MA) Nat Genet 2004 Apr;36(4):351-60 179 Citations |
| 1 | ABCA1-dependent lipid efflux to apolipoprotein A-I mediates HDL particle formation and decreases VLDL secretion from murine hepatocytes. (Sahoo D, Trischuk TC, Chan T, Drover VA, Ho S, Chimini G, Agellon LB, Agnihotri R, Francis GA, Lehner R) J Lipid Res 2004 Jun;45(6):1122-31 75 Citations |
| 1 | Overexpression of acid-sensing ion channel 1a in transgenic mice increases acquired fear-related behavior. (Wemmie JA, Coryell MW, Askwith CC, Lamani E, Leonard AS, Sigmund CD, Welsh MJ) Proc Natl Acad Sci U S A 2004 Mar 09;101(10):3621-6 177 Citations |
| 1 | Host conditioning is a primary determinant in modulating the effect of IL-7 on murine graft-versus-host disease. (Gendelman M, Hecht T, Logan B, Vodanovic-Jankovic S, Komorowski R, Drobyski WR) J Immunol 2004 Mar 01;172(5):3328-36 31 Citations |
| 1 | WIP regulates signaling via the high affinity receptor for immunoglobulin E in mast cells. (Kettner A, Kumar L, Antón IM, Sasahara Y, de la Fuente M, Pivniouk VI, Falet H, Hartwig JH, Geha RS) J Exp Med 2004 Feb 02;199(3):357-68 43 Citations |
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| 1 | Adipose depot-specific modulation of angiotensinogen gene expression in diet-induced obesity. (Rahmouni K, Mark AL, Haynes WG, Sigmund CD) Am J Physiol Endocrinol Metab 2004 Jun;286(6):E891-5 102 Citations |
| 1 | Moderate hypermutability of a transgenic lacZ reporter gene in Myc-dependent inflammation-induced plasma cell tumors in mice. (Felix K, Polack A, Pretsch W, Jackson SH, Feigenbaum L, Bornkamm GW, Janz S) Cancer Res 2004 Jan 15;64(2):530-7 5 Citations |
| 1 | PPAR(gamma) agonist rosiglitazone improves vascular function and lowers blood pressure in hypertensive transgenic mice. (Ryan MJ, Didion SP, Mathur S, Faraci FM, Sigmund CD) Hypertension 2004 Mar;43(3):661-6 177 Citations |
| 1 | A WT1 co-regulator controls podocyte phenotype by shuttling between adhesion structures and nucleus. (Srichai MB, Konieczkowski M, Padiyar A, Konieczkowski DJ, Mukherjee A, Hayden PS, Kamat S, El-Meanawy MA, Khan S, Mundel P, Lee SB, Bruggeman LA, Schelling JR, Sedor JR) J Biol Chem 2004 Apr 02;279(14):14398-408 77 Citations |
| 1 | Lck is required for activation-induced T cell death after TCR ligation with partial agonists. (Yu XZ, Levin SD, Madrenas J, Anasetti C) J Immunol 2004 Feb 01;172(3):1437-43 17 Citations |
| 1 | CD36 mediates the phagocytosis of Plasmodium falciparum-infected erythrocytes by rodent macrophages. (Patel SN, Serghides L, Smith TG, Febbraio M, Silverstein RL, Kurtz TW, Pravenec M, Kain KC) J Infect Dis 2004 Jan 15;189(2):204-13 111 Citations |
| 1 | Differential expression of the closely linked KISS1, REN, and FLJ10761 genes in transgenic mice. (Nistala R, Zhang X, Sigmund CD) Physiol Genomics 2004 Mar 12;17(1):4-10 9 Citations |
| 1 | Annexin II regulates fibrin homeostasis and neoangiogenesis in vivo. (Ling Q, Jacovina AT, Deora A, Febbraio M, Simantov R, Silverstein RL, Hempstead B, Mark WH, Hajjar KA) J Clin Invest 2004 Jan;113(1):38-48 339 Citations |
| 1 | Ganglionic action of angiotensin contributes to sympathetic activity in renin-angiotensinogen transgenic mice. (Ma X, Sigmund CD, Hingtgen SD, Tian X, Davisson RL, Abboud FM, Chapleau MW) Hypertension 2004 Feb;43(2):312-6 25 Citations |
| 1 | BCL2 accelerates inflammation-induced BALB/c plasmacytomas and promotes novel tumors with coexisting T(12;15) and T(6;15) translocations. (Silva S, Kovalchuk AL, Kim JS, Klein G, Janz S) Cancer Res 2003 Dec 15;63(24):8656-63 26 Citations |
| 1 | Inhibition of platelet-derived growth factor receptor phosphorylation by STI571 (Gleevec) reduces growth and metastasis of human pancreatic carcinoma in an orthotopic nude mouse model. (Hwang RF, Yokoi K, Bucana CD, Tsan R, Killion JJ, Evans DB, Fidler IJ) Clin Cancer Res 2003 Dec 15;9(17):6534-44 154 Citations |
| 1 | Sex differences in the behavioral response to spatial and object novelty in adult C57BL/6 mice. (Frick KM, Gresack JE) Behav Neurosci 2003 Dec;117(6):1283-91 176 Citations |
| 1 | Selective elimination of alloreactive donor T cells attenuates graft-versus-host disease and enhances T-cell reconstitution. (Gendelman M, Yassai M, Tivol E, Krueger A, Gorski J, Drobyski WR) Biol Blood Marrow Transplant 2003 Dec;9(12):742-52 11 Citations |
| 4 | Induction of megakaryocytes to synthesize and store a releasable pool of human factor VIII. (Wilcox DA, Shi Q, Nurden P, Haberichter SL, Rosenberg JB, Johnson BD, Nurden AT, White GC 2nd, Montgomery RR) J Thromb Haemost 2003 Dec;1(12):2477-89 54 Citations |
| 1 | Chronic hyperalgesia induced by repeated acid injections in muscle is abolished by the loss of ASIC3, but not ASIC1. (Sluka KA, Price MP, Breese NM, Stucky CL, Wemmie JA, Welsh MJ) Pain 2003 Dec;106(3):229-239 388 Citations |
| 1 | Impaired signaling via the high-affinity IgE receptor in Wiskott-Aldrich syndrome protein-deficient mast cells. (Pivniouk VI, Snapper SB, Kettner A, Alenius H, Laouini D, Falet H, Hartwig J, Alt FW, Geha RS) Int Immunol 2003 Dec;15(12):1431-40 41 Citations |
| 2 | CD200 is a novel p53-target gene involved in apoptosis-associated immune tolerance. (Rosenblum MD, Olasz E, Woodliff JE, Johnson BD, Konkol MC, Gerber KA, Orentas RJ, Sandford G, Truitt RL) Blood 2004 Apr 01;103(7):2691-8 72 Citations |
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| 1 | Formate, the toxic metabolite of methanol, in cultured ocular cells. (Treichel JL, Henry MM, Skumatz CM, Eells JT, Burke JM) Neurotoxicology 2003 Dec;24(6):825-34 40 Citations |
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| 1 | Imiquimod does not affect shedding of viable chlamydiae in a murine model of Chlamydia trachomatis genital tract infection. (Ramsey KH, Shaba N, Cohoon KP, Ault KA) Infect Dis Obstet Gynecol 2003;11(2):81-7 3 Citations |
| 1 | Cyclin E and Bcl-xL cooperatively induce cell cycle progression in c-Rel-/- B cells. (Cheng S, Hsia CY, Leone G, Liou HC) Oncogene 2003 Nov 20;22(52):8472-86 48 Citations |
| 1 | Localization of renin expressing cells in the brain, by use of a REN-eGFP transgenic model. (Lavoie JL, Cassell MD, Gross KW, Sigmund CD) Physiol Genomics 2004 Jan 15;16(2):240-6 73 Citations |
| 1 | Cause-effect relation between hyperfibrinogenemia and vascular disease. (Kerlin B, Cooley BC, Isermann BH, Hernandez I, Sood R, Zogg M, Hendrickson SB, Mosesson MW, Lord S, Weiler H) Blood 2004 Mar 01;103(5):1728-34 85 Citations |
| 1 | Untraditional methods for targeting the kidney in transgenic mice. (Bianco RA, Keen HL, Lavoie JL, Sigmund CD) Am J Physiol Renal Physiol 2003 Dec;285(6):F1027-33 10 Citations |
| 1 | Proteolytic release of the carboxy-terminal fragment of proHB-EGF causes nuclear export of PLZF. (Nanba D, Mammoto A, Hashimoto K, Higashiyama S) J Cell Biol 2003 Nov 10;163(3):489-502 140 Citations |
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| 1 | Diabetes and hyperlipidemia correlate with gallbladder contractility in leptin-related murine obesity. (Tran KQ, Goldblatt MI, Swartz-Basile DA, Svatek C, Nakeeb A, Pitt HA) J Gastrointest Surg 2003 Nov;7(7):857-62; discussion 863 42 Citations |
| 1 | Use of Hsf1(-/-) mice reveals an essential role for HSF1 to protect lung against cadmium-induced injury. (Wirth D, Christians E, Li X, Benjamin IJ, Gustin P) Toxicol Appl Pharmacol 2003 Oct 01;192(1):12-20 25 Citations |
| 1 | Heat shock protein 90 and tyrosine kinase regulate eNOS NO* generation but not NO* bioactivity. (Ou J, Fontana JT, Ou Z, Jones DW, Ackerman AW, Oldham KT, Yu J, Sessa WC, Pritchard KA Jr) Am J Physiol Heart Circ Physiol 2004 Feb;286(2):H561-9 53 Citations |
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| 1 | Antigen-specific immunity does not mediate acute regression of UVB-induced p53-mutant clones. (Remenyik E, Wikonkál NM, Zhang W, Paliwal V, Brash DE) Oncogene 2003 Sep 25;22(41):6369-76 33 Citations |
| 1 | CEP-701 and CEP-751 inhibit constitutively activated RET tyrosine kinase activity and block medullary thyroid carcinoma cell growth. (Strock CJ, Park JI, Rosen M, Dionne C, Ruggeri B, Jones-Bolin S, Denmeade SR, Ball DW, Nelkin BD) Cancer Res 2003 Sep 01;63(17):5559-63 92 Citations |
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| 1 | Mouse kidney expresses mRNA of four highly related sodium-glucose cotransporters: regulation by cadmium. (Tabatabai NM, Blumenthal SS, Lewand DL, Petering DH) Kidney Int 2003 Oct;64(4):1320-30 26 Citations |
| 1 | Glycosylation restores survival of chilled blood platelets. (Hoffmeister KM, Josefsson EC, Isaac NA, Clausen H, Hartwig JH, Stossel TP) Science 2003 Sep 12;301(5639):1531-4 246 Citations |
| 1 | Deficiency of the Nrf1 and Nrf2 transcription factors results in early embryonic lethality and severe oxidative stress. (Leung L, Kwong M, Hou S, Lee C, Chan JY) J Biol Chem 2003 Nov 28;278(48):48021-9 272 Citations |
| 1 | Crystal violet combined with Merocyanine 540 for the ex vivo purging of hematopoietic stem cell grafts. (Miyagi K, Sampson RW, Sieber-Blum M, Sieber F) J Photochem Photobiol B 2003 Jul;70(3):133-44 13 Citations |
| 1 | Paradoxical decrease in mutant frequencies and chromosomal rearrangements in a transgenic lacZ reporter gene in Ku80 null mice deficient in DNA double strand break repair. (Rockwood LD, Nussenzweig A, Janz S) Mutat Res 2003 Aug 28;529(1-2):51-8 15 Citations |
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| 1 | Phospholipase Cgamma2 provides survival signals via Bcl2 and A1 in different subpopulations of B cells. (Wen R, Chen Y, Xue L, Schuman J, Yang S, Morris SW, Wang D) J Biol Chem 2003 Oct 31;278(44):43654-62 37 Citations |
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| 1 | Male mice exhibit better spatial working and reference memory than females in a water-escape radial arm maze task. (Gresack JE, Frick KM) Brain Res 2003 Aug 22;982(1):98-107 69 Citations |
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| 1 | Metalloproteinase inhibitors improve the recovery and hemostatic function of in vitro-aged or -injured mouse platelets. (Bergmeier W, Burger PC, Piffath CL, Hoffmeister KM, Hartwig JH, Nieswandt B, Wagner DD) Blood 2003 Dec 01;102(12):4229-35 152 Citations |
| 1 | CrkIII: a novel and biologically distinct member of the Crk family of adaptor proteins. (Prosser S, Sorokina E, Pratt P, Sorokin A) Oncogene 2003 Jul 31;22(31):4799-806 26 Citations |
| 2 | PECAM-1 negatively regulates GPIb/V/IX signaling in murine platelets. (Rathore V, Stapleton MA, Hillery CA, Montgomery RR, Nichols TC, Merricks EP, Newman DK, Newman PJ) Blood 2003 Nov 15;102(10):3658-64 79 Citations |
| 1 | JUMONJI, a critical factor for cardiac development, functions as a transcriptional repressor. (Kim TG, Kraus JC, Chen J, Lee Y) J Biol Chem 2003 Oct 24;278(43):42247-55 82 Citations |
| 1 | Identification and characterization of E2F7, a novel mammalian E2F family member capable of blocking cellular proliferation. (de Bruin A, Maiti B, Jakoi L, Timmers C, Buerki R, Leone G) J Biol Chem 2003 Oct 24;278(43):42041-9 180 Citations |
| 1 | Duroquinone reduction during passage through the pulmonary circulation. (Audi SH, Bongard RD, Dawson CA, Siegel D, Roerig DL, Merker MP) Am J Physiol Lung Cell Mol Physiol 2003 Nov;285(5):L1116-31 23 Citations |
| 2 | Factor VIII ectopically expressed in platelets: efficacy in hemophilia A treatment. (Yarovoi HV, Kufrin D, Eslin DE, Thornton MA, Haberichter SL, Shi Q, Zhu H, Camire R, Fakharzadeh SS, Kowalska MA, Wilcox DA, Sachais BS, Montgomery RR, Poncz M) Blood 2003 Dec 01;102(12):4006-13 134 Citations |
| 1 | Effect of acute ethanol exposure on the dermal inflammatory response after burn injury. (Faunce DE, Garner JL, Llanas JN, Patel PJ, Gregory MS, Duffner LA, Gamelli RL, Kovacs EJ) Alcohol Clin Exp Res 2003 Jul;27(7):1199-206 32 Citations |
| 1 | Identification of T-cell epitopes in clotting factor IX and lack of tolerance in inbred mice. (Greenwood R, Wang B, Midkiff K, White GC 2nd, Lin HF, Frelinger JA) J Thromb Haemost 2003 Jan;1(1):95-102 16 Citations |
| 1 | Congenital lack of COX-2 affects mechanical and geometric properties of bone in mice. (Chen Q, Rho JY, Fan Z, Laulederkind SJ, Raghow R) Calcif Tissue Int 2003 Oct;73(4):387-92 34 Citations |
| 1 | Antenatal cell gene transfer: an immunological Trojan horse? (White GC 2nd) J Thromb Haemost 2003 Jan;1(1):14-5 1 Citation |
| 1 | Survival advantage associated with heterozygous factor V Leiden mutation in patients with severe sepsis and in mouse endotoxemia. (Kerlin BA, Yan SB, Isermann BH, Brandt JT, Sood R, Basson BR, Joyce DE, Weiler H, Dhainaut JF) Blood 2003 Nov 01;102(9):3085-92 141 Citations |
| 1 | Gene transfer establishes primacy of striated vs. smooth muscle sarcoglycan complex in limb-girdle muscular dystrophy. (Durbeej M, Sawatzki SM, Barresi R, Schmainda KM, Allamand V, Michele DE, Campbell KP) Proc Natl Acad Sci U S A 2003 Jul 22;100(15):8910-5 31 Citations |
| 1 | A single nucleotide polymorphism in the Emp3 gene defines the H4 minor histocompatibility antigen. (Luedtke B, Pooler LM, Choi EY, Tranchita AM, Reinbold CJ, Brown AC, Shaffer DJ, Roopenian DC, Malarkannan S) Immunogenetics 2003 Aug;55(5):284-95 12 Citations |
| 1 | Polycystin-1 distribution is modulated by polycystin-2 expression in mammalian cells. (Grimm DH, Cai Y, Chauvet V, Rajendran V, Zeltner R, Geng L, Avner ED, Sweeney W, Somlo S, Caplan MJ) J Biol Chem 2003 Sep 19;278(38):36786-93 77 Citations |
| 2 | The general anesthetic propofol increases brain N-arachidonylethanolamine (anandamide) content and inhibits fatty acid amide hydrolase. (Patel S, Wohlfeil ER, Rademacher DJ, Carrier EJ, Perry LJ, Kundu A, Falck JR, Nithipatikom K, Campbell WB, Hillard CJ) Br J Pharmacol 2003 Jul;139(5):1005-13 134 Citations |
| 1 | Selective loss of dopaminergic neurons in the substantia nigra of Pitx3-deficient aphakia mice. (Hwang DY, Ardayfio P, Kang UJ, Semina EV, Kim KS) Brain Res Mol Brain Res 2003 Jun 10;114(2):123-31 220 Citations |
| 1 | E1A oncogene-induced sensitization of human tumor cells to innate immune defenses and chemotherapy-induced apoptosis in vitro and in vivo. (Cook JL, Miura TA, Iklé DN, Lewis AM Jr, Routes JM) Cancer Res 2003 Jun 15;63(12):3435-43 16 Citations |
| 1 | BMP-7 counteracts TGF-beta1-induced epithelial-to-mesenchymal transition and reverses chronic renal injury. (Zeisberg M, Hanai J, Sugimoto H, Mammoto T, Charytan D, Strutz F, Kalluri R) Nat Med 2003 Jul;9(7):964-8 1228 Citations |
| 1 | Differential regulation of the endocannabinoids anandamide and 2-arachidonylglycerol within the limbic forebrain by dopamine receptor activity. (Patel S, Rademacher DJ, Hillard CJ) J Pharmacol Exp Ther 2003 Sep;306(3):880-8 138 Citations |
| 1 | Dual expression of CD80 and CD86 produces a tumor vaccine superior to single expression of either molecule. (Johnson BD, Yan X, Schauer DW, Orentas RJ) Cell Immunol 2003 Mar;222(1):15-26 29 Citations |
| 1 | Localized recruitment of a chromatin-remodeling activity by an activator in vivo drives transcriptional elongation. (Corey LL, Weirich CS, Benjamin IJ, Kingston RE) Genes Dev 2003 Jun 01;17(11):1392-401 118 Citations |
| 1 | Heat shock factor 1-independent activation of dendritic cells by heat shock: implication for the uncoupling of heat-mediated immunoregulation from the heat shock response. (Zheng H, Benjamin IJ, Basu S, Li Z) Eur J Immunol 2003 Jun;33(6):1754-62 30 Citations |
| 1 | Effects of environmental enrichment on spatial memory and neurochemistry in middle-aged mice. (Frick KM, Stearns NA, Pan JY, Berger-Sweeney J) Learn Mem 2003;10(3):187-98 139 Citations |
| 2 | Expression of human factor VIII under control of the platelet-specific alphaIIb promoter in megakaryocytic cell line as well as storage together with VWF. (Shi Q, Wilcox DA, Fahs SA, Kroner PA, Montgomery RR) Mol Genet Metab 2003 May;79(1):25-33 45 Citations |
| 1 | Embryogenesis and gene targeting of coagulation factors in mice. (Sood R, Weiler H) Best Pract Res Clin Haematol 2003 Jun;16(2):169-81 6 Citations |
| 1 | Membrane-anchoring and charge effects in the interaction of myelin basic protein with lipid bilayers studied by site-directed spin labeling. (Bates IR, Boggs JM, Feix JB, Harauz G) J Biol Chem 2003 Aug 01;278(31):29041-7 76 Citations |
| 1 | E mu/S mu transposition into Myc is sometimes a precursor for T(12;15) translocation in mouse B cells. (Kovalchuk AL, Kim JS, Janz S) Oncogene 2003 May 08;22(18):2842-50 8 Citations |
| 1 | Pigment epithelium-derived factor regulates the vasculature and mass of the prostate and pancreas. (Doll JA, Stellmach VM, Bouck NP, Bergh AR, Lee C, Abramson LP, Cornwell ML, Pins MR, Borensztajn J, Crawford SE) Nat Med 2003 Jun;9(6):774-80 272 Citations |
| 1 | Administration of optimal biological dose and schedule of interferon alpha combined with gemcitabine induces apoptosis in tumor-associated endothelial cells and reduces growth of human pancreatic carcinoma implanted orthotopically in nude mice. (Solorzano CC, Hwang R, Baker CH, Bucana CD, Pisters PW, Evans DB, Killion JJ, Fidler IJ) Clin Cancer Res 2003 May;9(5):1858-67 38 Citations |
| 1 | Effect of NASA light-emitting diode irradiation on molecular changes for wound healing in diabetic mice. (Whelan HT, Buchmann EV, Dhokalia A, Kane MP, Whelan NT, Wong-Riley MT, Eells JT, Gould LJ, Hammamieh R, Das R, Jett M) J Clin Laser Med Surg 2003 Apr;21(2):67-74 177 Citations |
| 1 | Rb function in extraembryonic lineages suppresses apoptosis in the CNS of Rb-deficient mice. (de Bruin A, Wu L, Saavedra HI, Wilson P, Yang Y, Rosol TJ, Weinstein M, Robinson ML, Leone G) Proc Natl Acad Sci U S A 2003 May 27;100(11):6546-51 111 Citations |
| 1 | L-4F, an apolipoprotein A-1 mimetic, dramatically improves vasodilation in hypercholesterolemia and sickle cell disease. (Ou J, Ou Z, Jones DW, Holzhauer S, Hatoum OA, Ackerman AW, Weihrauch DW, Gutterman DD, Guice K, Oldham KT, Hillery CA, Pritchard KA Jr) Circulation 2003 May 13;107(18):2337-41 140 Citations |
| 1 | Inactivation of E2F3 results in centrosome amplification. (Saavedra HI, Maiti B, Timmers C, Altura R, Tokuyama Y, Fukasawa K, Leone G) Cancer Cell 2003 Apr;3(4):333-46 64 Citations |
| 1 | DNA vaccination against mutant huntingtin ameliorates the HDR6/2 diabetic phenotype. (Miller TW, Shirley TL, Wolfgang WJ, Kang X, Messer A) Mol Ther 2003 May;7(5 Pt 1):572-9 57 Citations |
| 1 | Collaborative induction of inflammatory responses by dectin-1 and Toll-like receptor 2. (Gantner BN, Simmons RM, Canavera SJ, Akira S, Underhill DM) J Exp Med 2003 May 05;197(9):1107-17 1406 Citations |
| 1 | Enrichment enhances spatial memory and increases synaptophysin levels in aged female mice. (Frick KM, Fernandez SM) Neurobiol Aging 2003;24(4):615-26 265 Citations |
| 1 | Adenovirus E1A, not human papillomavirus E7, sensitizes tumor cells to lysis by macrophages through nitric oxide- and TNF-alpha-dependent mechanisms despite up-regulation of 70-kDa heat shock protein. (Miura TA, Morris K, Ryan S, Cook JL, Routes JM) J Immunol 2003 Apr 15;170(8):4119-26 19 Citations |
| 1 | The Grb10/Nedd4 complex regulates ligand-induced ubiquitination and stability of the insulin-like growth factor I receptor. (Vecchione A, Marchese A, Henry P, Rotin D, Morrione A) Mol Cell Biol 2003 May;23(9):3363-72 219 Citations |
| 1 | The absence of functional glucosylceramide synthase does not sensitize melanoma cells for anticancer drugs. (Veldman RJ, Mita A, Cuvillier O, Garcia V, Klappe K, Medin JA, Campbell JD, Carpentier S, Kok JW, Levade T) FASEB J 2003 Jun;17(9):1144-6 40 Citations |
| 2 | Signal transduction pathways mediated by PECAM-1: new roles for an old molecule in platelet and vascular cell biology. (Newman PJ, Newman DK) Arterioscler Thromb Vasc Biol 2003 Jun 01;23(6):953-64 359 Citations |
| 1 | Differentiating adult hippocampal stem cells into neural crest derivatives. (Alexanian AR, Sieber-Blum M) Neuroscience 2003;118(1):1-5 28 Citations |
| 1 | Protection against enteric salmonellosis in transgenic mice expressing a human intestinal defensin. (Salzman NH, Ghosh D, Huttner KM, Paterson Y, Bevins CL) Nature 2003 Apr 03;422(6931):522-6 675 Citations |
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| 1 | Structural requirements of SLP-76 in signaling via the high-affinity immunoglobulin E receptor (Fc epsilon RI) in mast cells. (Kettner A, Pivniouk V, Kumar L, Falet H, Lee JS, Mulligan R, Geha RS) Mol Cell Biol 2003 Apr;23(7):2395-406 36 Citations |
| 1 | Radiation increases the activity of oncolytic adenovirus cancer gene therapy vectors that overexpress the ADP (E3-11.6K) protein. (Toth K, Tarakanova V, Doronin K, Ward P, Kuppuswamy M, Locke JE, Dawson JE, Kim HJ, Wold WS) Cancer Gene Ther 2003 Mar;10(3):193-200 41 Citations |
| 1 | Preferential inactivation of paediatric solid tumour cells by sequential exposure to Merocyanine 540-mediated photodynamic therapy and Edelfosine: implications for the ex vivo purging of autologous haematopoietic stem cell grafts. (Anderson GS, Tsujino I, Miyagi K, Sampson R, Sieber F) J Photochem Photobiol B 2003 Feb;69(2):87-95 24 Citations |
| 1 | Wilms' tumor growth is suppressed by antiangiogenic pigment epithelium-derived factor in a xenograft model. (Abramson LP, Stellmach V, Doll JA, Cornwell M, Arensman RM, Crawford SE) J Pediatr Surg 2003 Mar;38(3):336-42; discussion 336-42 64 Citations |
| 1 | CD28 signal enhances apoptosis of CD8 T cells after strong TCR ligation. (Yu XZ, Martin PJ, Anasetti C) J Immunol 2003 Mar 15;170(6):3002-6 31 Citations |
| 1 | A threshold for central T cell tolerance to an inducible serum protein. (Haribhai D, Engle D, Meyer M, Donermeyer D, White JM, Williams CB) J Immunol 2003 Mar 15;170(6):3007-14 20 Citations |
| 1 | Elimination of leukemia in the absence of lethal graft-versus-host disease after allogenic bone marrow transplantation. (Drobyski WR, Gendelman M, Vodanovic-Jankovic S, Gorski J) J Immunol 2003 Mar 15;170(6):3046-53 16 Citations |
| 1 | Gene targeting in the mouse: advances in introduction of transgenes into the genome by homologous recombination. (Misra RP, Duncan SA) Endocrine 2002 Dec;19(3):229-38 43 Citations |
| 1 | Isolation of islets of Langerhans from rodent pancreas. (Kelly CB, Blair LA, Corbett JA, Scarim AL) Methods Mol Med 2003;83:3-14 49 Citations |
| 1 | Inhibition of constitutive NF-kappa B activity by I kappa B alpha M suppresses tumorigenesis. (Fujioka S, Sclabas GM, Schmidt C, Niu J, Frederick WA, Dong QG, Abbruzzese JL, Evans DB, Baker C, Chiao PJ) Oncogene 2003 Mar 06;22(9):1365-70 153 Citations |
| 1 | Identification of Shp-2 as a Stat5A phosphatase. (Chen Y, Wen R, Yang S, Schuman J, Zhang EE, Yi T, Feng GS, Wang D) J Biol Chem 2003 May 09;278(19):16520-7 101 Citations |
| 1 | ERK activation is required for double-stranded RNA- and virus-induced interleukin-1 expression by macrophages. (Maggi LB Jr, Moran JM, Buller RM, Corbett JA) J Biol Chem 2003 May 09;278(19):16683-9 38 Citations |
| 1 | Extra-embryonic function of Rb is essential for embryonic development and viability. (Wu L, de Bruin A, Saavedra HI, Starovic M, Trimboli A, Yang Y, Opavska J, Wilson P, Thompson JC, Ostrowski MC, Rosol TJ, Woollett LA, Weinstein M, Cross JC, Robinson ML, Leone G) Nature 2003 Feb 27;421(6926):942-7 333 Citations |
| 1 | Enteric salmonella infection inhibits Paneth cell antimicrobial peptide expression. (Salzman NH, Chou MM, de Jong H, Liu L, Porter EM, Paterson Y) Infect Immun 2003 Mar;71(3):1109-15 125 Citations |
| 1 | Microarray analysis of mRNA levels from RAW264.7 macrophages infected with Brucella abortus. (Eskra L, Mathison A, Splitter G) Infect Immun 2003 Mar;71(3):1125-33 95 Citations |
| 2 | Mechanisms and implications of platelet discoid shape. (Italiano JE Jr, Bergmeier W, Tiwari S, Falet H, Hartwig JH, Hoffmeister KM, André P, Wagner DD, Shivdasani RA) Blood 2003 Jun 15;101(12):4789-96 142 Citations |
| 1 | The thrombomodulin-protein C system is essential for the maintenance of pregnancy. (Isermann B, Sood R, Pawlinski R, Zogg M, Kalloway S, Degen JL, Mackman N, Weiler H) Nat Med 2003 Mar;9(3):331-7 231 Citations |
| 1 | Cannabinoid-induced Fos expression within A10 dopaminergic neurons. (Patel S, Hillard CJ) Brain Res 2003 Feb 14;963(1-2):15-25 58 Citations |
| 1 | Regulation of expression of the Borrelia burgdorferi beta(3)-chain integrin ligand, P66, in ticks and in culture. (Cugini C, Medrano M, Schwan TG, Coburn J) Infect Immun 2003 Feb;71(2):1001-7 44 Citations |
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| 1 | Redox imbalance and mutagenesis in spleens of mice harboring a hypomorphic allele of Gpdx(a) encoding glucose 6-phosphate dehydrogenase. (Felix K, Rockwood LD, Pretsch W, Bornkamm GW, Janz S) Free Radic Biol Med 2003 Jan 15;34(2):226-32 8 Citations |
| 1 | Differential response properties of IB(4)-positive and -negative unmyelinated sensory neurons to protons and capsaicin. (Dirajlal S, Pauers LE, Stucky CL) J Neurophysiol 2003 Jan;89(1):513-24 132 Citations |
| 1 | Regulation of cyclooxygenase-2 expression by macrophages in response to double-stranded RNA and viral infection. (Steer SA, Moran JM, Maggi LB Jr, Buller RM, Perlman H, Corbett JA) J Immunol 2003 Jan 15;170(2):1070-6 44 Citations |
| 1 | Bcl-2 reduces mutant rates in a transgenic lacZ reporter gene in mouse pre-B lymphocytes. (Felix K, Rolink A, Melchers F, Janz S) Mutat Res 2003 Jan 28;522(1-2):135-44 3 Citations |
| 1 | Primitive endothelial cell lines from the porcine embryonic yolk sac. (Plendl J, Gilligan BJ, Wang SJ, Lewis R, Shinners B, Vandenbroeck K, Auerbach R) In Vitro Cell Dev Biol Anim 2002 Jun;38(6):334-42 16 Citations |
| 1 | Cerebral arteriolar structure in mice overexpressing human renin and angiotensinogen. (Baumbach GL, Sigmund CD, Faraci FM) Hypertension 2003 Jan;41(1):50-5 87 Citations |
| 1 | Osteopontin is a critical inhibitor of calcium oxalate crystal formation and retention in renal tubules. (Wesson JA, Johnson RJ, Mazzali M, Beshensky AM, Stietz S, Giachelli C, Liaw L, Alpers CE, Couser WG, Kleinman JG, Hughes J) J Am Soc Nephrol 2003 Jan;14(1):139-47 258 Citations |
| 1 | CD36-mediated nonopsonic phagocytosis of erythrocytes infected with stage I and IIA gametocytes of Plasmodium falciparum. (Smith TG, Serghides L, Patel SN, Febbraio M, Silverstein RL, Kain KC) Infect Immun 2003 Jan;71(1):393-400 59 Citations |
| 1 | Regulation of alloresponses after bone marrow transplantation using donor T cells expressing a thymidine kinase suicide gene. (Drobyski WR, Gendelman M) Leuk Lymphoma 2002 Oct;43(10):2011-6 9 Citations |
| 2 | p38 isoforms have opposite effects on AP-1-dependent transcription through regulation of c-Jun. The determinant roles of the isoforms in the p38 MAPK signal specificity. (Pramanik R, Qi X, Borowicz S, Choubey D, Schultz RM, Han J, Chen G) J Biol Chem 2003 Feb 14;278(7):4831-9 133 Citations |
| 1 | Phospholipase C gamma 2 is essential for specific functions of Fc epsilon R and Fc gamma R. (Wen R, Jou ST, Chen Y, Hoffmeyer A, Wang D) J Immunol 2002 Dec 15;169(12):6743-52 65 Citations |
| 1 | Anti-tumor effect of Merocyanine 540-mediated photochemotherapy combined with Edelfosine: potential implications for the ex vivo purging of hematopoietic stem cell grafts from breast cancer patients. (Anderson GS, Miyagi K, Sampson RW, Sieber F) J Photochem Photobiol B 2002 Nov;68(2-3):101-8 24 Citations |
| 1 | Photochemical treatment of donor lymphocytes inhibited their ability to facilitate donor engraftment or increase donor chimerism after nonmyeloablative conditioning or establishment of mixed chimerism. (Johnson BD, Taylor PA, Stankowski MC, Talib S, Hearst JE, Blazar BR) Biol Blood Marrow Transplant 2002;8(11):581-7 |
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| 1 | GFR alpha2/neurturin signalling regulates noxious heat transduction in isolectin B4-binding mouse sensory neurons. (Stucky CL, Rossi J, Airaksinen MS, Lewin GR) J Physiol 2002 Nov 15;545(1):43-50 51 Citations |
| 1 | Structure of cerebral arterioles in cystathionine beta-synthase-deficient mice. (Baumbach GL, Sigmund CD, Bottiglieri T, Lentz SR) Circ Res 2002 Nov 15;91(10):931-7 64 Citations |
| 1 | Suppression of tumorigenesis and induction of p15(ink4b) by Smad4/DPC4 in human pancreatic cancer cells. (Peng B, Fleming JB, Breslin T, Grau AM, Fojioka S, Abbruzzese JL, Evans DB, Ayers D, Wathen K, Wu T, Robertson KD, Chiao PJ) Clin Cancer Res 2002 Nov;8(11):3628-38 59 Citations |
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| 1 | Analysis of 16S libraries of mouse gastrointestinal microflora reveals a large new group of mouse intestinal bacteria. (Salzman NH, de Jong H, Paterson Y, Harmsen HJM, Welling GW, Bos NA) Microbiology (Reading) 2002 Nov;148(Pt 11):3651-3660 217 Citations |
| 1 | Estrogen replacement improves spatial reference memory and increases hippocampal synaptophysin in aged female mice. (Frick KM, Fernandez SM, Bulinski SC) Neuroscience 2002;115(2):547-58 190 Citations |
| 1 | Real-time T-cell profiling identifies H60 as a major minor histocompatibility antigen in murine graft-versus-host disease. (Choi EY, Christianson GJ, Yoshimura Y, Jung N, Sproule TJ, Malarkannan S, Joyce S, Roopenian DC) Blood 2002 Dec 15;100(13):4259-65 62 Citations |
| 1 | Molecular cloning and sequencing of the human heme-regulated eukaryotic initiation factor 2 alpha (eIF-2 alpha) kinase from bone marrow culture. (Omasa T, Chen YG, Mantalaris A, Tsai YC, Wu JH) DNA Seq 2002 Jun;13(3):133-7 4 Citations |
| 1 | Heat shock transcription factor 2 is not essential for embryonic development, fertility, or adult cognitive and psychomotor function in mice. (McMillan DR, Christians E, Forster M, Xiao X, Connell P, Plumier JC, Zuo X, Richardson J, Morgan S, Benjamin IJ) Mol Cell Biol 2002 Nov;22(22):8005-14 66 Citations |
| 1 | Physiological significance of two common haplotypes of human angiotensinogen using gene targeting in the mouse. (Cvetkovic B, Keen HL, Zhang X, Davis D, Yang B, Sigmund CD) Physiol Genomics 2002 Dec 03;11(3):253-62 24 Citations |
| 1 | Expression of FAS within hypothalamic neurons: a model for decreased food intake after C75 treatment. (Kim EK, Miller I, Landree LE, Borisy-Rudin FF, Brown P, Tihan T, Townsend CA, Witters LA, Moran TH, Kuhajda FP, Ronnett GV) Am J Physiol Endocrinol Metab 2002 Nov;283(5):E867-79 125 Citations |
| 1 | Genomic instability in mouse Burkitt lymphoma is dominated by illegitimate genetic recombinations, not point mutations. (Rockwood LD, Torrey TA, Kim JS, Coleman AE, Kovalchuk AL, Xiang S, Ried T, Morse HC 3rd, Janz S) Oncogene 2002 Oct 17;21(47):7235-40 24 Citations |
| 1 | Subunits of IgM reconstitute defective contact sensitivity in B-1 cell-deficient xid mice: kappa light chains recruit T cells independent of complement. (Paliwal V, Tsuji RF, Szczepanik M, Kawikova I, Campos RA, Kneilling M, Röcken M, Schuurman J, Redegeld FA, Nijkamp FP, Askenase PW) J Immunol 2002 Oct 15;169(8):4113-23 27 Citations |
| 1 | Angiotensin mutant mice: a focus on the brain renin-angiotensin system. (Morimoto S, Sigmund CD) Neuropeptides 2002;36(2-3):194-200 32 Citations |
| 1 | Mouse heat shock transcription factor 1 deficiency alters cardiac redox homeostasis and increases mitochondrial oxidative damage. (Yan LJ, Christians ES, Liu L, Xiao X, Sohal RS, Benjamin IJ) EMBO J 2002 Oct 01;21(19):5164-72 205 Citations |
| 1 | Overexpression of A(3) adenosine receptors decreases heart rate, preserves energetics, and protects ischemic hearts. (Cross HR, Murphy E, Black RG, Auchampach J, Steenbergen C) Am J Physiol Heart Circ Physiol 2002 Oct;283(4):H1562-8 62 Citations |
| 1 | Superoxide contributes to vascular dysfunction in mice that express human renin and angiotensinogen. (Didion SP, Ryan MJ, Baumbach GL, Sigmund CD, Faraci FM) Am J Physiol Heart Circ Physiol 2002 Oct;283(4):H1569-76 60 Citations |
| 1 | Production of macrophage migration inhibitory factor by human and murine neuroblastoma. (Bin Q, Johnson BD, Schauer DW, Casper JT, Orentas RJ) Tumour Biol 2002;23(3):123-9 22 Citations |
| 1 | Isotype switch-mediated CH deletions are a recurrent feature of Myc/CH translocations in peritoneal plasmacytomas in mice. (Kovalchuk AL, Janz S) Int J Cancer 2002 Oct 10;101(5):423-6 5 Citations |
| 1 | Differential binding to and biofilm formation on, HEp-2 cells by Salmonella enterica serovar Typhimurium is dependent upon allelic variation in the fimH gene of the fim gene cluster. (Boddicker JD, Ledeboer NA, Jagnow J, Jones BD, Clegg S) Mol Microbiol 2002 Sep;45(5):1255-65 115 Citations |
| 2 | Normal Arp2/3 complex activation in platelets lacking WASp. (Falet H, Hoffmeister KM, Neujahr R, Hartwig JH) Blood 2002 Sep 15;100(6):2113-22 61 Citations |
| 1 | Neurotrophin-4: a survival factor for adult sensory neurons. (Stucky CL, Shin JB, Lewin GR) Curr Biol 2002 Aug 20;12(16):1401-4 56 Citations |
| 1 | Mechanism of magnesium activation of calcium-activated potassium channels. (Shi J, Krishnamoorthy G, Yang Y, Hu L, Chaturvedi N, Harilal D, Qin J, Cui J) Nature 2002 Aug 22;418(6900):876-80 183 Citations |
| 1 | Novel role for calcium-independent phospholipase A(2) in the macrophage antiviral response of inducible nitric-oxide synthase expression. (Maggi LB Jr, Moran JM, Scarim AL, Ford DA, Yoon JW, McHowat J, Buller RM, Corbett JA) J Biol Chem 2002 Oct 11;277(41):38449-55 40 Citations |
| 1 | A Bax-induced pro-oxidant state is critical for cytochrome c release during programmed neuronal death. (Kirkland RA, Windelborn JA, Kasprzak JM, Franklin JL) J Neurosci 2002 Aug 01;22(15):6480-90 160 Citations |
| 1 | Conditioned place preference after single doses or "binge" cocaine in C57BL/6J and 129/J mice. (Zhang Y, Mantsch JR, Schlussman SD, Ho A, Kreek MJ) Pharmacol Biochem Behav 2002 Oct;73(3):655-62 |
| 1 | A novel family of atherogenic oxidized phospholipids promotes macrophage foam cell formation via the scavenger receptor CD36 and is enriched in atherosclerotic lesions. (Podrez EA, Poliakov E, Shen Z, Zhang R, Deng Y, Sun M, Finton PJ, Shan L, Febbraio M, Hajjar DP, Silverstein RL, Hoff HF, Salomon RG, Hazen SL) J Biol Chem 2002 Oct 11;277(41):38517-23 352 Citations |
| 1 | Gene dosage-dependent effects of cardiac-specific overexpression of the A3 adenosine receptor. (Black RG Jr, Guo Y, Ge ZD, Murphree SS, Prabhu SD, Jones WK, Bolli R, Auchampach JA) Circ Res 2002 Jul 26;91(2):165-72 78 Citations |
| 1 | Role of the passive apoptotic pathway in graft-versus-host disease. (Drobyski WR, Komorowski R, Logan B, Gendelman M) J Immunol 2002 Aug 01;169(3):1626-33 14 Citations |
| 2 | Intravenous anesthetic, propofol inhibits invasion of cancer cells. (Mammoto T, Mukai M, Mammoto A, Yamanaka Y, Hayashi Y, Mashimo T, Kishi Y, Nakamura H) Cancer Lett 2002 Oct 28;184(2):165-70 149 Citations |
| 2 | Infiltration anesthetic lidocaine inhibits cancer cell invasion by modulating ectodomain shedding of heparin-binding epidermal growth factor-like growth factor (HB-EGF). (Mammoto T, Higashiyama S, Mukai M, Mammoto A, Ayaki M, Mashimo T, Hayashi Y, Kishi Y, Nakamura H, Akedo H) J Cell Physiol 2002 Sep;192(3):351-8 54 Citations |
| 1 | Neutralization of IL-18 attenuates lipopolysaccharide-induced myocardial dysfunction. (Raeburn CD, Dinarello CA, Zimmerman MA, Calkins CM, Pomerantz BJ, McIntyre RC Jr, Harken AH, Meng X) Am J Physiol Heart Circ Physiol 2002 Aug;283(2):H650-7 74 Citations |
| 1 | Reduced focal adhesion kinase and paxillin phosphorylation in BCR-ABL-transfected cells. (Cheng K, Kurzrock R, Qiu X, Estrov Z, Ku S, Dulski KM, Wang JY, Talpaz M) Cancer 2002 Jul 15;95(2):440-50 23 Citations |
| 1 | Regulation of renin expression and blood pressure by vitamin D(3). (Sigmund CD) J Clin Invest 2002 Jul;110(2):155-6 62 Citations |
| 1 | ICAM-1 and VCAM-1 mediate endotoxemic myocardial dysfunction independent of neutrophil accumulation. (Raeburn CD, Calkins CM, Zimmerman MA, Song Y, Ao L, Banerjee A, Harken AH, Meng X) Am J Physiol Regul Integr Comp Physiol 2002 Aug;283(2):R477-86 81 Citations |
| 1 | Both constitutive and inducible prostaglandin H synthase affect dermal wound healing in mice. (Laulederkind SJ, Thompson-Jaeger S, Goorha S, Chen Q, Fu A, Rho JY, Ballou LR, Raghow R) Lab Invest 2002 Jul;82(7):919-27 28 Citations |
| 1 | Lymphopenia in the BB rat model of type 1 diabetes is due to a mutation in a novel immune-associated nucleotide (Ian)-related gene. (MacMurray AJ, Moralejo DH, Kwitek AE, Rutledge EA, Van Yserloo B, Gohlke P, Speros SJ, Snyder B, Schaefer J, Bieg S, Jiang J, Ettinger RA, Fuller J, Daniels TL, Pettersson A, Orlebeke K, Birren B, Jacob HJ, Lander ES, Lernmark A) Genome Res 2002 Jul;12(7):1029-39 193 Citations |
| 1 | Structural characterization of Rasgrf1 and a novel linked imprinted locus. (de la Puente A, Hall J, Wu YZ, Leone G, Peters J, Yoon BJ, Soloway P, Plass C) Gene 2002 May 29;291(1-2):287-97 31 Citations |
| 1 | Generation and characterization of a protective monoclonal antibody to Pseudomonas aeruginosa PcrV. (Frank DW, Vallis A, Wiener-Kronish JP, Roy-Burman A, Spack EG, Mullaney BP, Megdoud M, Marks JD, Fritz R, Sawa T) J Infect Dis 2002 Jul 01;186(1):64-73 135 Citations |
| 1 | Transgenic shuttle vector assays for determining genetic differences in oxidative B cell mutagenesis in vivo. (Felix K, Rockwood LD, Janz S) Methods Enzymol 2002;353:434-48 3 Citations |
| 1 | Glia- and neuron-specific expression of the renin-angiotensin system in brain alters blood pressure, water intake, and salt preference. (Morimoto S, Cassell MD, Sigmund CD) J Biol Chem 2002 Sep 06;277(36):33235-41 104 Citations |
| 1 | Specificity of E2F1, E2F2, and E2F3 in mediating phenotypes induced by loss of Rb. (Saavedra HI, Wu L, de Bruin A, Timmers C, Rosol TJ, Weinstein M, Robinson ML, Leone G) Cell Growth Differ 2002 May;13(5):215-25 94 Citations |
| 1 | Epicutaneous application of protein antigens incorporated into cosmetic cream induces antigen-nonspecific unresponsiveness in mice and affects the cell-mediated immune response. (Ptak W, Szczepanik M, Bryniarski K, Tutaj M, Ptak M) Int Arch Allergy Immunol 2002 May;128(1):8-14 31 Citations |
| 1 | Decreased gallbladder response in leptin-deficient obese mice. (Goldblatt MI, Swartz-Basile DA, Svatek CL, Nakeeb A, Pitt HA) J Gastrointest Surg 2002;6(3):438-42; discussion 443-4 53 Citations |
| 1 | Toll-like receptor-4 signaling mediates pulmonary neutrophil sequestration in response to gram-positive bacterial enterotoxin. (Calkins CM, Barsness K, Bensard DD, Vasquez-Torres A, Raeburn CD, Meng X, McIntyre RC Jr) J Surg Res 2002 May 15;104(2):124-30 22 Citations |
| 1 | Effect of multivitamins in an effervescent preparation on the respiratory burst of peritoneal macrophages in mice. (Jakus J, Kriska T, Vanyúr R) Br J Nutr 2002 May;87(5):501-8 10 Citations |
| 1 | Neuron-specific expression of human angiotensinogen in brain causes increased salt appetite. (Morimoto S, Cassell MD, Sigmund CD) Physiol Genomics 2002;9(2):113-20 35 Citations |
| 1 | alpha-Adrenergic response and myofilament activity in mouse hearts lacking PKC phosphorylation sites on cardiac TnI. (Montgomery DE, Wolska BM, Pyle WG, Roman BB, Dowell JC, Buttrick PM, Koretsky AP, Del Nido P, Solaro RJ) Am J Physiol Heart Circ Physiol 2002 Jun;282(6):H2397-405 59 Citations |
| 1 | Structural and functional relationships between Ca2+ puffs and mitochondria in Xenopus oocytes. (Marchant JS, Ramos V, Parker I) Am J Physiol Cell Physiol 2002 Jun;282(6):C1374-86 44 Citations |
| 1 | Relationships between Rap1b, affinity modulation of integrin alpha IIbbeta 3, and the actin cytoskeleton. (Bertoni A, Tadokoro S, Eto K, Pampori N, Parise LV, White GC, Shattil SJ) J Biol Chem 2002 Jul 12;277(28):25715-21 171 Citations |
| 1 | CD36 mediates the cardiovascular action of growth hormone-releasing peptides in the heart. (Bodart V, Febbraio M, Demers A, McNicoll N, Pohankova P, Perreault A, Sejlitz T, Escher E, Silverstein RL, Lamontagne D, Ong H) Circ Res 2002 May 03;90(8):844-9 149 Citations |
| 1 | Differential abilities of central nervous system resident endothelial cells and astrocytes to serve as inducible antigen-presenting cells. (Girvin AM, Gordon KB, Welsh CJ, Clipstone NA, Miller SD) Blood 2002 May 15;99(10):3692-701 49 Citations |
| 1 | Spi-B can functionally replace PU.1 in myeloid but not lymphoid development. (Dahl R, Ramirez-Bergeron DL, Rao S, Simon MC) EMBO J 2002 May 01;21(9):2220-30 40 Citations |
| 1 | Soluble proteins and haptens on bone marrow-derived dendritic cells are presented to host CD4 T cells in an MHC-restricted manner. (Olasz EB, Linton J, Katz SI) Int Immunol 2002 May;14(5):493-502 4 Citations |
| 1 | Moderate G6PD deficiency increases mutation rates in the brain of mice. (Felix K, Rockwood LD, Pretsch W, Nair J, Bartsch H, Bornkamm GW, Janz S) Free Radic Biol Med 2002 Apr 01;32(7):663-73 21 Citations |
| 1 | Brain-selective overexpression of angiotensin (AT1) receptors causes enhanced cardiovascular sensitivity in transgenic mice. (Lazartigues E, Dunlay SM, Loihl AK, Sinnayah P, Lang JA, Espelund JJ, Sigmund CD, Davisson RL) Circ Res 2002 Mar 22;90(5):617-24 70 Citations |
| 1 | Molecular cloning, genomic organization, genetic variations, and characterization of murine sterolin genes Abcg5 and Abcg8. (Lu K, Lee MH, Yu H, Zhou Y, Sandell SA, Salen G, Patel SB) J Lipid Res 2002 Apr;43(4):565-78 57 Citations |
| 1 | Expression of Bcl-2 family member Bid in normal and malignant tissues. (Krajewska M, Zapata JM, Meinhold-Heerlein I, Hedayat H, Monks A, Bettendorf H, Shabaik A, Bubendorf L, Kallioniemi OP, Kim H, Reifenberger G, Reed JC, Krajewski S) Neoplasia 2002;4(2):129-40 83 Citations |
| 1 | Use of transgenic and knockout strategies in mice. (Ryan MJ, Sigmund CD) Semin Nephrol 2002 Mar;22(2):154-60 3 Citations |
| 1 | Lower blood pressure in floxed angiotensinogen mice after adenoviral delivery of Cre-recombinase. (Stec DE, Keen HL, Sigmund CD) Hypertension 2002 Feb;39(2 Pt 2):629-33 24 Citations |
| 1 | Opening of compacted chromatin by early developmental transcription factors HNF3 (FoxA) and GATA-4. (Cirillo LA, Lin FR, Cuesta I, Friedman D, Jarnik M, Zaret KS) Mol Cell 2002 Feb;9(2):279-89 964 Citations |
| 1 | Nonhematopoietic expression of Janus kinase 3 is required for efficient recruitment of Th2 lymphocytes and eosinophils in OVA-induced airway inflammation. (Verbsky JW, Randolph DA, Shornick LP, Chaplin DD) J Immunol 2002 Mar 01;168(5):2475-82 14 Citations |
| 1 | Cellular sources and targets of IFN-gamma-mediated protection against viral demyelination and neurological deficits. (Murray PD, McGavern DB, Pease LR, Rodriguez M) Eur J Immunol 2002 Mar;32(3):606-15 32 Citations |
| 1 | The gastrin receptor promotes pancreatic growth in transgenic mice. (Yen TW, Sandgren EP, Liggitt HD, Palmiter RD, Zhou W, Hinds TR, Grippo PJ, McDonald JM, Robinson LM, Bell RH Jr) Pancreas 2002 Mar;24(2):121-9 14 Citations |
| 1 | Chemokine expression in the central nervous system of mice with a viral disease resembling multiple sclerosis: roles of CD4+ and CD8+ T cells and viral persistence. (Ransohoff RM, Wei T, Pavelko KD, Lee JC, Murray PD, Rodriguez M) J Virol 2002 Mar;76(5):2217-24 43 Citations |
| 1 | Osteopontin--a molecule for all seasons. (Mazzali M, Kipari T, Ophascharoensuk V, Wesson JA, Johnson R, Hughes J) QJM 2002 Jan;95(1):3-13 362 Citations |
| 1 | The 5-HT3 subtype of serotonin receptor contributes to nociceptive processing via a novel subset of myelinated and unmyelinated nociceptors. (Zeitz KP, Guy N, Malmberg AB, Dirajlal S, Martin WJ, Sun L, Bonhaus DW, Stucky CL, Julius D, Basbaum AI) J Neurosci 2002 Feb 01;22(3):1010-9 329 Citations |
| 1 | Interleukin-1 plus gamma-interferon-induced pancreatic beta-cell dysfunction is mediated by beta-cell nitric oxide production. (Thomas HE, Darwiche R, Corbett JA, Kay TW) Diabetes 2002 Feb;51(2):311-6 158 Citations |
| 1 | Heat shock factor 1-mediated thermotolerance prevents cell death and results in G2/M cell cycle arrest. (Luft JC, Benjamin IJ, Mestril R, Dix DJ) Cell Stress Chaperones 2001 Oct;6(4):326-36 48 Citations |
| 1 | IL-6 transgenic mouse model for extraosseous plasmacytoma. (Kovalchuk AL, Kim JS, Park SS, Coleman AE, Ward JM, Morse HC 3rd, Kishimoto T, Potter M, Janz S) Proc Natl Acad Sci U S A 2002 Feb 05;99(3):1509-14 114 Citations |
| 1 | Fluorine-18 labeled mouse bone marrow-derived dendritic cells can be detected in vivo by high resolution projection imaging. (Olasz EB, Lang L, Seidel J, Green MV, Eckelman WC, Katz SI) J Immunol Methods 2002 Feb 01;260(1-2):137-48 65 Citations |
| 1 | Endothelial dysfunction and blood pressure variability in selected inbred mouse strains. (Ryan MJ, Didion SP, Davis DR, Faraci FM, Sigmund CD) Arterioscler Thromb Vasc Biol 2002 Jan;22(1):42-8 67 Citations |
| 1 | The brain renin-angiotensin system in transgenic mice carrying a highly regulated human renin transgene. (Morimoto S, Cassell MD, Sigmund CD) Circ Res 2002 Jan 11;90(1):80-6 43 Citations |
| 1 | Generation of single-copy transgenic mouse embryos directly from ES cells by tetraploid embryo complementation. (Misra RP, Bronson SK, Xiao Q, Garrison W, Li J, Zhao R, Duncan SA) BMC Biotechnol 2001;1:12 29 Citations |
| 1 | Differential requirement for SLP-76 domains in T cell development and function. (Myung PS, Derimanov GS, Jordan MS, Punt JA, Liu QH, Judd BA, Meyers EE, Sigmund CD, Freedman BD, Koretzky GA) Immunity 2001 Dec;15(6):1011-26 89 Citations |
| 1 | Differential cardiopulmonary recruitment of neutrophils during hemorrhagic shock: a role for ICAM-1? (Song Y, Ao L, Calkins CM, Raeburn CD, Harken AH, Meng X) Shock 2001 Dec;16(6):444-8 15 Citations |
| 1 | Gene therapy for Fabry disease. (Siatskas C, Medin JA) J Inherit Metab Dis 2001;24 Suppl 2:25-41; discussion 11-2 35 Citations |
| 1 | Sex differences in neurochemical markers that correlate with behavior in aging mice. (Frick KM, Burlingame LA, Delaney SS, Berger-Sweeney J) Neurobiol Aging 2002;23(1):145-58 36 Citations |
| 1 | Donor natural killer (NK1.1+) cells do not play a role in the suppression of GVHD or in the mediation of GVL reactions after DLI. (Johnson BD, Dagher N, Stankowski WC, Hanke CA, Truitt RL) Biol Blood Marrow Transplant 2001;7(11):589-95 11 Citations |
| 2 | Effect of NASA light-emitting diode irradiation on wound healing. (Whelan HT, Smits RL Jr, Buchman EV, Whelan NT, Turner SG, Margolis DA, Cevenini V, Stinson H, Ignatius R, Martin T, Cwiklinski J, Philippi AF, Graf WR, Hodgson B, Gould L, Kane M, Chen G, Caviness J) J Clin Laser Med Surg 2001 Dec;19(6):305-14 426 Citations |
| 1 | Role of the innate immune response in determining the tumorigenicity of neoplastic cells. (Cook JL, Routes JM) Dev Biol (Basel) 2001;106:99-107; discussion 107-8, 143-60 3 Citations |
| 1 | Differential regulation of mouse kidney sodium-dependent transporters mRNA by cadmium. (Tabatabai NM, Blumenthal SS, Lewand DL, Petering DH) Toxicol Appl Pharmacol 2001 Dec 15;177(3):163-73 32 Citations |
| 1 | Hexosamines regulate leptin production in 3T3-L1 adipocytes through transcriptional mechanisms. (Zhang P, Klenk ES, Lazzaro MA, Williams LB, Considine RV) Endocrinology 2002 Jan;143(1):99-106 38 Citations |
| 1 | Rat Genome Database (RGD): mapping disease onto the genome. (Twigger S, Lu J, Shimoyama M, Chen D, Pasko D, Long H, Ginster J, Chen CF, Nigam R, Kwitek A, Eppig J, Maltais L, Maglott D, Schuler G, Jacob H, Tonellato PJ) Nucleic Acids Res 2002 Jan 01;30(1):125-8 93 Citations |
| 1 | Electrofusion of a weakly immunogenic neuroblastoma with dendritic cells produces a tumor vaccine. (Orentas RJ, Schauer D, Bin Q, Johnson BD) Cell Immunol 2001 Oct 10;213(1):4-13 57 Citations |
| 1 | Apolipoprotein A-I alpha -helices 7 and 8 modulate high density lipoprotein subclass distribution. (Reschly EJ, Sorci-Thomas MG, Davidson WS, Meredith SC, Reardon CA, Getz GS) J Biol Chem 2002 Mar 22;277(12):9645-54 37 Citations |
| 1 | TNF receptor I mediates chemokine production and neutrophil accumulation in the lung following systemic lipopolysaccharide. (Calkins CM, Heimbach JK, Bensard DD, Song Y, Raeburn CD, Meng X, McIntyre RC Jr) J Surg Res 2001 Dec;101(2):232-7 37 Citations |
| 1 | Additive effects of anti-CD3 and anti-CD28 prolongation of allogeneic skin graft survival. (Yu XZ, Nitta Y, Bidwell SJ, Anasetti C) Transplantation 2001 Dec 15;72(11):1862 1 Citation |
| 1 | DNA damage invokes mismatch repair-dependent cyclin D1 attenuation and retinoblastoma signaling pathways to inhibit CDK2. (Lan Z, Sever-Chroneos Z, Strobeck MW, Park CH, Baskaran R, Edelmann W, Leone G, Knudsen ES) J Biol Chem 2002 Mar 08;277(10):8372-81 56 Citations |
| 1 | The E2F1-3 transcription factors are essential for cellular proliferation. (Wu L, Timmers C, Maiti B, Saavedra HI, Sang L, Chong GT, Nuckolls F, Giangrande P, Wright FA, Field SJ, Greenberg ME, Orkin S, Nevins JR, Robinson ML, Leone G) Nature 2001 Nov 22;414(6862):457-62 520 Citations |
| 1 | Requirement for Ca2+/calmodulin-dependent kinase type IV/Gr in setting the thymocyte selection threshold. (Raman V, Blaeser F, Ho N, Engle DL, Williams CB, Chatila TA) J Immunol 2001 Dec 01;167(11):6270-8 25 Citations |
| 1 | BAALC, the human member of a novel mammalian neuroectoderm gene lineage, is implicated in hematopoiesis and acute leukemia. (Tanner SM, Austin JL, Leone G, Rush LJ, Plass C, Heinonen K, Mrózek K, Sill H, Knuutila S, Kolitz JE, Archer KJ, Caligiuri MA, Bloomfield CD, de La Chapelle A) Proc Natl Acad Sci U S A 2001 Nov 20;98(24):13901-6 118 Citations |
| 1 | Macrophage-specific expression of human lipoprotein lipase accelerates atherosclerosis in transgenic apolipoprotein e knockout mice but not in C57BL/6 mice. (Wilson K, Fry GL, Chappell DA, Sigmund CD, Medh JD) Arterioscler Thromb Vasc Biol 2001 Nov;21(11):1809-15 59 Citations |
| 1 | Cannabinoid-receptor-independent cell signalling by N-acylethanolamines. (Berdyshev EV, Schmid PC, Krebsbach RJ, Hillard CJ, Huang C, Chen N, Dong Z, Schmid HH) Biochem J 2001 Nov 15;360(Pt 1):67-75 72 Citations |
| 1 | Role of interferon regulatory factor-1 in double-stranded RNA-induced iNOS expression by mouse islets. (Blair LA, Maggi LB Jr, Scarim AL, Corbett JA) J Biol Chem 2002 Jan 04;277(1):359-65 34 Citations |
| 1 | Automated construction of high-density comparative maps between rat, human, and mouse. (Kwitek AE, Tonellato PJ, Chen D, Gullings-Handley J, Cheng YS, Twigger S, Scheetz TE, Casavant TL, Stoll M, Nobrega MA, Shiozawa M, Soares MB, Sheffield VC, Jacob HJ) Genome Res 2001 Nov;11(11):1935-43 36 Citations |
| 1 | Bicarbonate enhances peroxidase activity of Cu,Zn-superoxide dismutase. Role of carbonate anion radical and scavenging of carbonate anion radical by metalloporphyrin antioxidant enzyme mimetics. (Zhang H, Joseph J, Gurney M, Becker D, Kalyanaraman B) J Biol Chem 2002 Jan 11;277(2):1013-20 99 Citations |
| 1 | Genetic manipulation of the renin-angiotensin system in the kidney. (Sigmund CD) Acta Physiol Scand 2001 Sep;173(1):67-73 8 Citations |
| 1 | PU.1/Spi-B regulation of c-rel is essential for mature B cell survival. (Hu CJ, Rao S, Ramirez-Bergeron DL, Garrett-Sinha LA, Gerondakis S, Clark MR, Simon MC) Immunity 2001 Oct;15(4):545-55 42 Citations |
| 1 | Monomeric solution structure of the prototypical 'C' chemokine lymphotactin. (Kuloglu ES, McCaslin DR, Kitabwalla M, Pauza CD, Markley JL, Volkman BF) Biochemistry 2001 Oct 23;40(42):12486-96 59 Citations |
| 1 | Phenotypic analysis of conditionally immortalized cells isolated from the BPK model of ARPKD. (Sweeney WE Jr, Kusner L, Carlin CR, Chang S, Futey L, Cotton CU, Dell KM, Avner ED) Am J Physiol Cell Physiol 2001 Nov;281(5):C1695-705 22 Citations |
| 1 | Distal limb malformations: underlying mechanisms and clinical associations. (Sifakis S, Basel D, Ianakiev P, Kilpatrick M, Tsipouras P) Clin Genet 2001 Sep;60(3):165-72 33 Citations |
| 1 | MHC class I molecules on adenovirus E1A-expressing tumor cells inhibit NK cell killing but not NK cell-mediated tumor rejection. (Routes JM, Ryan JC, Ryan S, Nakamura M) Int Immunol 2001 Oct;13(10):1301-7 5 Citations |
| 1 | A novel inhibitor of tumor necrosis factor-alpha converting enzyme ameliorates polycystic kidney disease. (Dell KM, Nemo R, Sweeney WE Jr, Levin JI, Frost P, Avner ED) Kidney Int 2001 Oct;60(4):1240-8 64 Citations |
| 1 | Critical roles of a cyclic AMP responsive element and an E-box in regulation of mouse renin gene expression. (Pan L, Black TA, Shi Q, Jones CA, Petrovic N, Loudon J, Kane C, Sigmund CD, Gross KW) J Biol Chem 2001 Dec 07;276(49):45530-8 114 Citations |
| 1 | 7-Dehydrocholesterol-dependent proteolysis of HMG-CoA reductase suppresses sterol biosynthesis in a mouse model of Smith-Lemli-Opitz/RSH syndrome. (Fitzky BU, Moebius FF, Asaoka H, Waage-Baudet H, Xu L, Xu G, Maeda N, Kluckman K, Hiller S, Yu H, Batta AK, Shefer S, Chen T, Salen G, Sulik K, Simoni RD, Ness GC, Glossmann H, Patel SB, Tint GS) J Clin Invest 2001 Sep;108(6):905-15 146 Citations |
| 1 | Vectors for high-level expression of cDNAs controlled by tissue-specific promoters in transgenic mice. (Stec DE, Morimoto S, Sigmund CD) Biotechniques 2001 Aug;31(2):256-8, 260 16 Citations |
| 1 | Early postnatal cardiac changes and premature death in transgenic mice overexpressing a mutant form of serum response factor. (Zhang X, Chai J, Azhar G, Sheridan P, Borras AM, Furr MC, Khrapko K, Lawitts J, Misra RP, Wei JY) J Biol Chem 2001 Oct 26;276(43):40033-40 69 Citations |
| 1 | Myc requires distinct E2F activities to induce S phase and apoptosis. (Leone G, Sears R, Huang E, Rempel R, Nuckolls F, Park CH, Giangrande P, Wu L, Saavedra HI, Field SJ, Thompson MA, Yang H, Fujiwara Y, Greenberg ME, Orkin S, Smith C, Nevins JR) Mol Cell 2001 Jul;8(1):105-13 218 Citations |
| 1 | Deficiency in beta(2)-microglobulin, but not CD1, accelerates spontaneous lupus skin disease while inhibiting nephritis in MRL-Fas(lpr) nice: an example of disease regulation at the organ level. (Chan OT, Paliwal V, McNiff JM, Park SH, Bendelac A, Shlomchik MJ) J Immunol 2001 Sep 01;167(5):2985-90 71 Citations |
| 1 | Elevated blood pressure in transgenic mice with brain-specific expression of human angiotensinogen driven by the glial fibrillary acidic protein promoter. (Morimoto S, Cassell MD, Beltz TG, Johnson AK, Davisson RL, Sigmund CD) Circ Res 2001 Aug 17;89(4):365-72 97 Citations |
| 1 | Disrupted bile acid homeostasis reveals an unexpected interaction among nuclear hormone receptors, transporters, and cytochrome P450. (Schuetz EG, Strom S, Yasuda K, Lecureur V, Assem M, Brimer C, Lamba J, Kim RB, Ramachandran V, Komoroski BJ, Venkataramanan R, Cai H, Sinal CJ, Gonzalez FJ, Schuetz JD) J Biol Chem 2001 Oct 19;276(42):39411-8 362 Citations |
| 1 | A low level of TNF-alpha mediates hemorrhage-induced acute lung injury via p55 TNF receptor. (Song Y, Ao L, Raeburn CD, Calkins CM, Abraham E, Harken AH, Meng X) Am J Physiol Lung Cell Mol Physiol 2001 Sep;281(3):L677-84 61 Citations |
| 1 | PcrV immunization enhances survival of burned Pseudomonas aeruginosa-infected mice. (Holder IA, Neely AN, Frank DW) Infect Immun 2001 Sep;69(9):5908-10 78 Citations |
| 1 | Vascular cell adhesion molecule--1 expression is obligatory for endotoxin-induced myocardial neutrophil accumulation and contractile dysfunction. (Raeburn CD, Calkins CM, Zimmerman MA, Song Y, Ao L, Banerjee A, Meng X, Harken AH) Surgery 2001 Aug;130(2):319-25 42 Citations |
| 1 | Mechanisms of beta-cell death in response to double-stranded (ds) RNA and interferon-gamma: dsRNA-dependent protein kinase apoptosis and nitric oxide-dependent necrosis. (Scarim AL, Arnush M, Blair LA, Concepcion J, Heitmeier MR, Scheuner D, Kaufman RJ, Ryerse J, Buller RM, Corbett JA) Am J Pathol 2001 Jul;159(1):273-83 53 Citations |
| 1 | Nitric oxide induces murine thymocyte apoptosis by oxidative injury and a p53-dependent mechanism. (Gordon SA, Abou-Jaoude W, Hoffman RA, McCarthy SA, Kim YM, Zhou X, Zhang XR, Simmons RL, Chen Y, Schall L, Ford HR) J Leukoc Biol 2001 Jul;70(1):87-95 35 Citations |
| 1 | Multiphoton-evoked color change of DsRed as an optical highlighter for cellular and subcellular labeling. (Marchant JS, Stutzmann GE, Leissring MA, LaFerla FM, Parker I) Nat Biotechnol 2001 Jul;19(7):645-9 93 Citations |
| 1 | Conformational differences in the 3-D nanostructure of the immunoglobulin heavy-chain locus, a hotspot of chromosomal translocations in B lymphocytes. (Esa A, Coleman AE, Edelmann P, Silva S, Cremer CG, Janz S) Cancer Genet Cytogenet 2001 Jun;127(2):168-73 23 Citations |
| 1 | Role for E2F in control of both DNA replication and mitotic functions as revealed from DNA microarray analysis. (Ishida S, Huang E, Zuzan H, Spang R, Leone G, West M, Nevins JR) Mol Cell Biol 2001 Jul;21(14):4684-99 515 Citations |
| 1 | A 76-bp deletion in the Mip gene causes autosomal dominant cataract in Hfi mice. (Sidjanin DJ, Parker-Wilson DM, Neuhäuser-Klaus A, Pretsch W, Favor J, Deen PM, Ohtaka-Maruyama C, Lu Y, Bragin A, Skach WR, Chepelinsky AB, Grimes PA, Stambolian DE) Genomics 2001 Jun 15;74(3):313-9 40 Citations |
| 1 | Spontaneous remyelination following extensive demyelination is associated with improved neurological function in a viral model of multiple sclerosis. (Murray PD, McGavern DB, Sathornsumetee S, Rodriguez M) Brain 2001 Jul;124(Pt 7):1403-16 62 Citations |
| 1 | TNF receptor I is required for induction of macrophage heat shock protein 70. (Heimbach JK, Reznikov LL, Calkins CM, Robinson TN, Dinarello CA, Harken AH, Meng X) Am J Physiol Cell Physiol 2001 Jul;281(1):C241-7 15 Citations |
| 1 | Endothelial dysfunction and elevation of S-adenosylhomocysteine in cystathionine beta-synthase-deficient mice. (Dayal S, Bottiglieri T, Arning E, Maeda N, Malinow MR, Sigmund CD, Heistad DD, Faraci FM, Lentz SR) Circ Res 2001 Jun 08;88(11):1203-9 203 Citations |
| 1 | Physiological insights from genetic manipulation of the renin-angiotensin system. (Stec DE, Sigmund CD) News Physiol Sci 2001 Apr;16:80-4 7 Citations |
| 1 | Non-Hodgkin lymphomas of mice. (Hori M, Xiang S, Qi CF, Chattopadhyay SK, Fredrickson TN, Hartley JW, Kovalchuk AL, Bornkamm GW, Janz S, Copeland NG, Jenkins NA, Ward JM, Morse HC 3rd) Blood Cells Mol Dis 2001;27(1):217-22 12 Citations |
| 1 | Production of MDC/CCL22 by human intestinal epithelial cells. (Berin MC, Dwinell MB, Eckmann L, Kagnoff MF) Am J Physiol Gastrointest Liver Physiol 2001 Jun;280(6):G1217-26 63 Citations |
| 1 | Mycobacterium bovis strain bacillus Calmette-Guérin-induced liver granulomas contain a diverse TCR repertoire, but a monoclonal T cell population is sufficient for protective granuloma formation. (Hogan LH, Macvilay K, Barger B, Co D, Malkovska I, Fennelly G, Sandor M) J Immunol 2001 May 15;166(10):6367-75 32 Citations |
| 1 | Cell surface glypicans are low-affinity endostatin receptors. (Karumanchi SA, Jha V, Ramchandran R, Karihaloo A, Tsiokas L, Chan B, Dhanabal M, Hanai JI, Venkataraman G, Shriver Z, Keiser N, Kalluri R, Zeng H, Mukhopadhyay D, Chen RL, Lander AD, Hagihara K, Yamaguchi Y, Sasisekharan R, Cantley L, Sukhatme VP) Mol Cell 2001 Apr;7(4):811-22 278 Citations |
| 1 | Characterisation of Wnt gene expression during the differentiation of murine embryonic stem cells in vitro: role of Wnt3 in enhancing haematopoietic differentiation. (Lako M, Lindsay S, Lincoln J, Cairns PM, Armstrong L, Hole N) Mech Dev 2001 May;103(1-2):49-59 70 Citations |
| 2 | Mechanisms of cold-induced platelet actin assembly. (Hoffmeister KM, Falet H, Toker A, Barkalow KL, Stossel TP, Hartwig JH) J Biol Chem 2001 Jul 06;276(27):24751-9 86 Citations |
| 1 | Expression of the orpk disease gene during kidney development and maturation. (Nakanishi K, Sweeney WE Jr, Avner ED, Murcia NS) Pediatr Nephrol 2001 Mar;16(3):219-26 5 Citations |
| 1 | Anti-CD3 epsilon F(ab')2 prevents graft-versus-host disease by selectively depleting donor T cells activated by recipient alloantigens. (Yu XZ, Bidwell SJ, Martin PJ, Anasetti C) J Immunol 2001 May 01;166(9):5835-9 33 Citations |
| 1 | PU.1 exhibits partial functional redundancy with Spi-B, but not with Ets-1 or Elf-1. (Garrett-Sinha LA, Dahl R, Rao S, Barton KP, Simon MC) Blood 2001 May 01;97(9):2908-12 46 Citations |
| 1 | Increased mRNA expression for the alpha(1) subunit of the GABA(A) receptor following nitrous oxide exposure in mice. (Johanek LM, Cullinan WE, Vaughn LK) Brain Res Mol Brain Res 2001 Apr 18;89(1-2):41-9 5 Citations |
| 1 | Cannabinoid CB(1) receptor agonists produce cerebellar dysfunction in mice. (Patel S, Hillard CJ) J Pharmacol Exp Ther 2001 May;297(2):629-37 78 Citations |
| 1 | Protection from lethal murine graft-versus-host disease without compromise of alloengraftment using transgenic donor T cells expressing a thymidine kinase suicide gene. (Drobyski WR, Morse HC 3rd, Burns WH, Casper JT, Sandford G) Blood 2001 Apr 15;97(8):2506-13 26 Citations |
| 1 | Positional cloning of a novel gene on chromosome 16q causing Bardet-Biedl syndrome (BBS2). (Nishimura DY, Searby CC, Carmi R, Elbedour K, Van Maldergem L, Fulton AB, Lam BL, Powell BR, Swiderski RE, Bugge KE, Haider NB, Kwitek-Black AE, Ying L, Duhl DM, Gorman SW, Heon E, Iannaccone A, Bonneau D, Biesecker LG, Jacobson SG, Stone EM, Sheffield VC) Hum Mol Genet 2001 Apr 01;10(8):865-74 213 Citations |
| 1 | Bradykinin B2 receptors activate Na+/H+ exchange in mIMCD-3 cells via Janus kinase 2 and Ca2+/calmodulin. (Mukhin YV, Vlasova T, Jaffa AA, Collinsworth G, Bell JL, Tholanikunnel BG, Pettus T, Fitzgibbon W, Ploth DW, Raymond JR, Garnovskaya MN) J Biol Chem 2001 May 18;276(20):17339-46 26 Citations |
| 1 | Interleukin-6 promotes post-traumatic healing in the central nervous system. (Swartz KR, Liu F, Sewell D, Schochet T, Campbell I, Sandor M, Fabry Z) Brain Res 2001 Mar 30;896(1-2):86-95 145 Citations |
| 1 | Role of CFTR in autosomal recessive polycystic kidney disease. (Nakanishi K, Sweeney WE Jr, Macrae Dell K, Cotton CU, Avner ED) J Am Soc Nephrol 2001 Apr;12(4):719-725 35 Citations |
| 1 | Targeted deletion of the A3 adenosine receptor confers resistance to myocardial ischemic injury and does not prevent early preconditioning. (Guo Y, Bolli R, Bao W, Wu WJ, Black RG Jr, Murphree SS, Salvatore CA, Jacobson MA, Auchampach JA) J Mol Cell Cardiol 2001 Apr;33(4):825-30 70 Citations |
| 1 | Double-stranded RNA-dependent protein kinase is not required for double-stranded RNA-induced nitric oxide synthase expression or nuclear factor-kappaB activation by islets. (Blair LA, Heitmeier MR, Scarim AL, Maggi LB Jr, Corbett JA) Diabetes 2001 Feb;50(2):283-90 24 Citations |
| 1 | Spatial reference memory and neocortical neurochemistry vary with the estrous cycle in C57BL/6 mice. (Frick KM, Berger-Sweeney J) Behav Neurosci 2001 Feb;115(1):229-37 114 Citations |
| 1 | Quantitative analysis of the immune response to mouse non-MHC transplantation antigens in vivo: the H60 histocompatibility antigen dominates over all others. (Choi EY, Yoshimura Y, Christianson GJ, Sproule TJ, Malarkannan S, Shastri N, Joyce S, Roopenian DC) J Immunol 2001 Apr 01;166(7):4370-9 69 Citations |
| 1 | Mycobacterium bovis BCG-induced granuloma formation depends on gamma interferon and CD40 ligand but does not require CD28. (Hogan LH, Markofski W, Bock A, Barger B, Morrissey JD, Sandor M) Infect Immun 2001 Apr;69(4):2596-603 40 Citations |
| 1 | Regulated MIP-3alpha/CCL20 production by human intestinal epithelium: mechanism for modulating mucosal immunity. (Izadpanah A, Dwinell MB, Eckmann L, Varki NM, Kagnoff MF) Am J Physiol Gastrointest Liver Physiol 2001 Apr;280(4):G710-9 209 Citations |
| 1 | Preselective gene therapy for Fabry disease. (Qin G, Takenaka T, Telsch K, Kelley L, Howard T, Levade T, Deans R, Howard BH, Malech HL, Brady RO, Medin JA) Proc Natl Acad Sci U S A 2001 Mar 13;98(6):3428-33 70 Citations |
| 1 | Cardiomyopathy in transgenic mice with cardiac-specific overexpression of serum response factor. (Zhang X, Azhar G, Chai J, Sheridan P, Nagano K, Brown T, Yang J, Khrapko K, Borras AM, Lawitts J, Misra RP, Wei JY) Am J Physiol Heart Circ Physiol 2001 Apr;280(4):H1782-92 134 Citations |
| 2 | Platelet endothelial cell adhesion molecule-1 serves as an inhibitory receptor that modulates platelet responses to collagen. (Patil S, Newman DK, Newman PJ) Blood 2001 Mar 15;97(6):1727-32 145 Citations |
| 1 | Paradoxical regulation of short promoter human renin transgene by angiotensin ii. (Keen HL, Sigmund CD) Hypertension 2001 Feb;37(2 Pt 2):403-7 11 Citations |
| 1 | Type III secretion/intoxication system important in virulence of Pseudomonas aeruginosa infections in burns. (Holder IA, Neely AN, Frank DW) Burns 2001 Mar;27(2):129-30 70 Citations |
| 1 | Renal dysfunction but not cystic change is ameliorated by neonatal epidermal growth factor in bpk mice. (Nakanishi K, Gattone VH 2nd, Sweeney WE, Avner ED) Pediatr Nephrol 2001 Jan;16(1):45-50 21 Citations |
| 1 | Regulated production of interferon-inducible T-cell chemoattractants by human intestinal epithelial cells. (Dwinell MB, Lügering N, Eckmann L, Kagnoff MF) Gastroenterology 2001 Jan;120(1):49-59 181 Citations |
| 1 | Vocal cord augmentation with cultured autologous fibroblasts. (Berke G, Blumin J, Sebastian J, Keller G, Revazova E) Bull Exp Biol Med 2000 Aug;130(8):790-2 5 Citations |
| 1 | Translocation remodeling in the primary BALB/c plasmacytoma TEPC 3610. (Kovalchuk AL, Esa A, Coleman AE, Park SS, Ried T, Cremer CC, Janz S) Genes Chromosomes Cancer 2001 Mar;30(3):283-91 10 Citations |
| 1 | Inducible mutagenesis in TEPC 2372, a mouse plasmacytoma cell line that harbors the transgenic shuttle vector lambdaLIZ. (Felix K, Kovalchuk AL, Park SS, Coleman AE, Ramsay ES, Qian M, Kelliher KA, Jones GM, Ried T, Bornkamm GW, Janz S) Mutat Res 2001 Jan 25;473(1):121-36 1 Citation |
| 1 | Genetic variability in the response of normal murine hematopoietic progenitor cells to extracorporeal photochemotherapy. (Tsujino I, Sieber F) Photochem Photobiol 2000 Dec;72(6):810-4 4 Citations |
| 1 | Identification of a gene, ABCG5, important in the regulation of dietary cholesterol absorption. (Lee MH, Lu K, Hazard S, Yu H, Shulenin S, Hidaka H, Kojima H, Allikmets R, Sakuma N, Pegoraro R, Srivastava AK, Salen G, Dean M, Patel SB) Nat Genet 2001 Jan;27(1):79-83 620 Citations |
| 1 | Platelet activation by a relapsing fever spirochaete results in enhanced bacterium-platelet interaction via integrin alphaIIbbeta3 activation. (Alugupalli KR, Michelson AD, Barnard MR, Robbins D, Coburn J, Baker EK, Ginsberg MH, Schwan TG, Leong JM) Mol Microbiol 2001 Jan;39(2):330-40 41 Citations |
| 1 | Androgen-dependent regulation of human angiotensinogen expression in KAP-hAGT transgenic mice. (Ding Y, Sigmund CD) Am J Physiol Renal Physiol 2001 Jan;280(1):F54-60 47 Citations |
| 1 | Generation and phenotype of cell lines derived from CF and non-CF mice that carry the H-2K(b)-tsA58 transgene. (Takacs-Jarrett M, Sweeney WE, Avner ED, Cotton CU) Am J Physiol Cell Physiol 2001 Jan;280(1):C228-36 18 Citations |
| 1 | Antianalgesic action of nociceptin originating in the brain is mediated by spinal prostaglandin E(2) in mice. (Rady JJ, Campbell WB, Fujimoto JM) J Pharmacol Exp Ther 2001 Jan;296(1):7-14 16 Citations |
| 1 | Phase I study of chimeric human/murine anti-ganglioside G(D2) monoclonal antibody (ch14.18) with granulocyte-macrophage colony-stimulating factor in children with neuroblastoma immediately after hematopoietic stem-cell transplantation: a Children's Cancer Group Study. (Ozkaynak MF, Sondel PM, Krailo MD, Gan J, Javorsky B, Reisfeld RA, Matthay KK, Reaman GH, Seeger RC) J Clin Oncol 2000 Dec 15;18(24):4077-85 173 Citations |
| 1 | Mice are not little rats: species differences in a one-day water maze task. (Frick KM, Stillner ET, Berger-Sweeney J) Neuroreport 2000 Nov 09;11(16):3461-5 139 Citations |
| 1 | Genetic evidence that lethality in angiotensinogen-deficient mice is due to loss of systemic but not renal angiotensinogen. (Ding Y, Stec DE, Sigmund CD) J Biol Chem 2001 Mar 09;276(10):7431-6 20 Citations |
| 1 | Diametric effects of bacterial endotoxin lipopolysaccharide on adrenal and Leydig cell steroidogenic acute regulatory protein. (Hales KH, Diemer T, Ginde S, Shankar BK, Roberts M, Bosmann HB, Hales DB) Endocrinology 2000 Nov;141(11):4000-12 78 Citations |
| 1 | Roles of SLP-76, phosphoinositide 3-kinase, and gelsolin in the platelet shape changes initiated by the collagen receptor GPVI/FcR gamma-chain complex. (Falet H, Barkalow KL, Pivniouk VI, Barnes MJ, Geha RS, Hartwig JH) Blood 2000 Dec 01;96(12):3786-92 50 Citations |
| 1 | Expression of chick Tbx-2, Tbx-3, and Tbx-5 genes during early heart development: evidence for BMP2 induction of Tbx2. (Yamada M, Revelli JP, Eichele G, Barron M, Schwartz RJ) Dev Biol 2000 Dec 01;228(1):95-105 186 Citations |
| 1 | Induction of prostaglandin endoperoxide synthase 2 by mitogen-activated protein kinase cascades. (McGinty A, Foschi M, Chang YW, Han J, Dunn MJ, Sorokin A) Biochem J 2000 Dec 01;352 Pt 2(Pt 2):419-24 27 Citations |
| 1 | Non-Fc receptor-binding humanized anti-CD3 antibodies induce apoptosis of activated human T cells. (Carpenter PA, Pavlovic S, Tso JY, Press OW, Gooley T, Yu XZ, Anasetti C) J Immunol 2000 Dec 01;165(11):6205-13 94 Citations |
| 1 | Antitumor interaction of short-course endostatin and ionizing radiation. (Hanna NN, Seetharam S, Mauceri HJ, Beckett MA, Jaskowiak NT, Salloum RM, Hari D, Dhanabal M, Ramchandran R, Kalluri R, Sukhatme VP, Kufe DW, Weichselbaum RR) Cancer J 2000;6(5):287-93 60 Citations |
| 1 | Identification of CD8+ T-cell-stimulating antigen genes in cDNA libraries. (Mendoza LM, Malarkannan S, Shastri N) Methods Mol Biol 2001;156:255-63 3 Citations |
| 1 | The mammalian sodium channel BNC1 is required for normal touch sensation. (Price MP, Lewin GR, McIlwrath SL, Cheng C, Xie J, Heppenstall PA, Stucky CL, Mannsfeldt AG, Brennan TJ, Drummond HA, Qiao J, Benson CJ, Tarr DE, Hrstka RF, Yang B, Williamson RA, Welsh MJ) Nature 2000 Oct 26;407(6807):1007-11 448 Citations |
| 1 | Generation of antigen-specific, lacZ-inducible T-cell hybrids. (Malarkannan S, Mendoza LM, Shastri N) Methods Mol Biol 2001;156:265-72 18 Citations |
| 1 | A migratory population of skin-derived dendritic cells expresses CXCR5, responds to B lymphocyte chemoattractant in vitro, and co-localizes to B cell zones in lymph nodes in vivo. (Saeki H, Wu MT, Olasz E, Hwang ST) Eur J Immunol 2000 Oct;30(10):2808-14 64 Citations |
| 1 | Retinoic acid-mediated activation of the mouse renin enhancer. (Shi Q, Gross KW, Sigmund CD) J Biol Chem 2001 Feb 02;276(5):3597-603 59 Citations |
| 2 | Invariant chains with the class II binding site replaced by a sequence from influenza virus matrix protein constrain low-affinity sequences to MHC II presentation. (Carstens C, Newman DK, Bohlen H, König A, Koch N) Int Immunol 2000 Nov;12(11):1561-8 10 Citations |
| 1 | Dissimilar immunogenicities of human papillomavirus E7 and adenovirus E1A proteins influence primary tumor development. (Routes JM, Ryan S, Li H, Steinke J, Cook JL) Virology 2000 Nov 10;277(1):48-57 16 Citations |
| 1 | Munc18c regulates insulin-stimulated glut4 translocation to the transverse tubules in skeletal muscle. (Khan AH, Thurmond DC, Yang C, Ceresa BP, Sigmund CD, Pessin JE) J Biol Chem 2001 Feb 09;276(6):4063-9 68 Citations |
| 1 | Adoptive transfer of acute lung injury. (Moxley MA, Baird TL, Corbett JA) Am J Physiol Lung Cell Mol Physiol 2000 Nov;279(5):L985-93 14 Citations |
| 1 | Maternal effect of Hsf1 on reproductive success. (Christians E, Davis AA, Thomas SD, Benjamin IJ) Nature 2000 Oct 12;407(6805):693-4 243 Citations |
| 1 | Burkitt lymphoma in the mouse. (Kovalchuk AL, Qi CF, Torrey TA, Taddesse-Heath L, Feigenbaum L, Park SS, Gerbitz A, Klobeck G, Hoertnagel K, Polack A, Bornkamm GW, Janz S, Morse HC 3rd) J Exp Med 2000 Oct 16;192(8):1183-90 186 Citations |
| 1 | Contrast agent-enhanced magnetic resonance imaging of skeletal muscle damage in animal models of muscular dystrophy. (Straub V, Donahue KM, Allamand V, Davisson RL, Kim YR, Campbell KP) Magn Reson Med 2000 Oct;44(4):655-9 56 Citations |
| 1 | mTert expression correlates with telomerase activity during the differentiation of murine embryonic stem cells. (Armstrong L, Lako M, Lincoln J, Cairns PM, Hole N) Mech Dev 2000 Oct;97(1-2):109-16 105 Citations |
| 1 | Expression of mPer1 and mPer2, two mammalian clock genes, in murine bone marrow. (Chen YG, Mantalaris A, Bourne P, Keng P, Wu JH) Biochem Biophys Res Commun 2000 Sep 24;276(2):724-8 44 Citations |
| 1 | Differences that matter: major cytotoxic T cell-stimulating minor histocompatibility antigens. (Malarkannan S, Horng T, Eden P, Gonzalez F, Shih P, Brouwenstijn N, Klinge H, Christianson G, Roopenian D, Shastri N) Immunity 2000 Sep;13(3):333-44 76 Citations |
| 1 | Identification of three human renin mRNA isoforms from alternative tissue-specific transcriptional initiation. (Sinn PL, Sigmund CD) Physiol Genomics 2000 Jun 29;3(1):25-31 94 Citations |
| 1 | Novel mechanism of hypertension revealed by cell-specific targeting of human angiotensinogen in transgenic mice. (Davisson RL, Ding Y, Stec DE, Catterall JF, Sigmund CD) Physiol Genomics 1999 Jul 15;1(1):3-9 111 Citations |
| 1 | The serpin alpha1-proteinase inhibitor is a critical substrate for gelatinase B/MMP-9 in vivo. (Liu Z, Zhou X, Shapiro SD, Shipley JM, Twining SS, Diaz LA, Senior RM, Werb Z) Cell 2000 Sep 01;102(5):647-55 353 Citations |
| 1 | Early adenovirus-mediated gene transfer effectively prevents muscular dystrophy in alpha-sarcoglycan-deficient mice. (Allamand V, Donahue KM, Straub V, Davisson RL, Davidson BL, Campbell KP) Gene Ther 2000 Aug;7(16):1385-91 41 Citations |
| 1 | Transgenic and knockout mice to study the renin-angiotensin system and other interacting vasoactive pathways. (Lake-Bruse KD, Sigmund CD) Curr Hypertens Rep 2000 Apr;2(2):211-6 9 Citations |
| 1 | The p38 pathway provides negative feedback for Ras proliferative signaling. (Chen G, Hitomi M, Han J, Stacey DW) J Biol Chem 2000 Dec 15;275(50):38973-80 160 Citations |
| 1 | Desflurane induces only minor Ca2+ release from the sarcoplasmic reticulum of mammalian skeletal muscle. (Kunst G, Stucke AG, Graf BM, Martin E, Fink RH) Anesthesiology 2000 Sep;93(3):832-6 19 Citations |
| 1 | Induction of a heat shock factor 1-dependent stress response alters the cytotoxic activity of hsp90-binding agents. (Bagatell R, Paine-Murrieta GD, Taylor CW, Pulcini EJ, Akinaga S, Benjamin IJ, Whitesell L) Clin Cancer Res 2000 Aug;6(8):3312-8 250 Citations |
| 1 | Preparation of Der p 1 specific monoclonal antibodies and use in a two-site-ELISA to detect Der p 1 allergen. (Chien TI, Chen YG, Chiang BL) J Microbiol Immunol Infect 2000 Jun;33(2):87-92 3 Citations |
| 1 | Use of serial analysis of gene expression to generate kidney expression libraries. (El-Meanawy MA, Schelling JR, Pozuelo F, Churpek MM, Ficker EK, Iyengar S, Sedor JR) Am J Physiol Renal Physiol 2000 Aug;279(2):F383-92 32 Citations |
| 1 | Chromosomes 1 and 5 harbor plasmacytoma progressor genes in mice. (Coleman AE, Ried T, Janz S) Genes Chromosomes Cancer 2000 Sep;29(1):70-4 11 Citations |
| 1 | TS+OCD-like neuropotentiated mice are supersensitive to seizure induction. (Campbell KM, Veldman MB, McGrath MJ, Burton FH) Neuroreport 2000 Jul 14;11(10):2335-8 26 Citations |
| 1 | Defective uptake and utilization of long chain fatty acids in muscle and adipose tissues of CD36 knockout mice. (Coburn CT, Knapp FF Jr, Febbraio M, Beets AL, Silverstein RL, Abumrad NA) J Biol Chem 2000 Oct 20;275(42):32523-9 588 Citations |
| 1 | Cholesterol as a singlet oxygen detector in biological systems. (Girotti AW, Korytowski W) Methods Enzymol 2000;319:85-100 71 Citations |
| 1 | Adoptively transferred gamma delta T cells indirectly regulate murine graft-versus-host reactivity following donor leukocyte infusion therapy in mice. (Drobyski WR, Vodanovic-Jankovic S, Klein J) J Immunol 2000 Aug 01;165(3):1634-40 38 Citations |
| 1 | Potential role of PKR in double-stranded RNA-induced macrophage activation. (Maggi LB Jr, Heitmeier MR, Scheuner D, Kaufman RJ, Buller RM, Corbett JA) EMBO J 2000 Jul 17;19(14):3630-8 73 Citations |
| 1 | Divergent functions of angiotensin II receptor isoforms in the brain. (Davisson RL, Oliverio MI, Coffman TM, Sigmund CD) J Clin Invest 2000 Jul;106(1):103-6 167 Citations |
| 1 | Chronic propranolol induces deficits in retention but not acquisition performance in the water maze in mice. (Czech DA, Nielson KA, Laubmeier KK) Neurobiol Learn Mem 2000 Jul;74(1):17-26 19 Citations |
| 1 | Biphasic and regionally-restricted chemokine expression in the central nervous system in the Theiler's virus model of multiple sclerosis. (Murray PD, Krivacic K, Chernosky A, Wei T, Ransohoff RM, Rodriguez M) J Neurovirol 2000 May;6 Suppl 1:S44-52 34 Citations |
| 1 | Anti-inflammatory actions of 15-deoxy-delta 12,14-prostaglandin J2 and troglitazone: evidence for heat shock-dependent and -independent inhibition of cytokine-induced inducible nitric oxide synthase expression. (Maggi LB Jr, Sadeghi H, Weigand C, Scarim AL, Heitmeier MR, Corbett JA) Diabetes 2000 Mar;49(3):346-55 118 Citations |
| 1 | CD36 in atherosclerosis. The role of a class B macrophage scavenger receptor. (Nicholson AC, Febbraio M, Han J, Silverstein RL, Hajjar DP) Ann N Y Acad Sci 2000 May;902:128-31; discussion 131-3 69 Citations |
| 1 | Lymph nodes and Peyer's patches of IL-6 transgenic BALB/c mice harbor T(12;15) translocated plasma cells that contain illegitimate exchanges between the immunoglobulin heavy-chain mu locus and c-myc. (Kovalchuk AL, Kishimoto T, Janz S) Leukemia 2000 Jun;14(6):1127-35 19 Citations |
| 1 | Deletion in the promoter region and altered expression of Pitx3 homeobox gene in aphakia mice. (Semina EV, Murray JC, Reiter R, Hrstka RF, Graw J) Hum Mol Genet 2000 Jul 01;9(11):1575-85 166 Citations |
| 1 | Hypoalgesia and altered inflammatory responses in mice lacking kinin B1 receptors. (Pesquero JB, Araujo RC, Heppenstall PA, Stucky CL, Silva JA Jr, Walther T, Oliveira SM, Pesquero JL, Paiva AC, Calixto JB, Lewin GR, Bader M) Proc Natl Acad Sci U S A 2000 Jul 05;97(14):8140-5 340 Citations |
| 1 | Viewpoint: are studies in genetically altered mice out of control? (Sigmund CD) Arterioscler Thromb Vasc Biol 2000 Jun;20(6):1425-9 111 Citations |
| 1 | Long-term enzyme correction and lipid reduction in multiple organs of primary and secondary transplanted Fabry mice receiving transduced bone marrow cells. (Takenaka T, Murray GJ, Qin G, Quirk JM, Ohshima T, Qasba P, Clark K, Kulkarni AB, Brady RO, Medin JA) Proc Natl Acad Sci U S A 2000 Jun 20;97(13):7515-20 92 Citations |
| 1 | Expression of smooth muscle myosin light chain 17 and unloaded shortening in single smooth muscle cells. (Eddinger TJ, Korwek AA, Meer DP, Sherwood JJ) Am J Physiol Cell Physiol 2000 Jun;278(6):C1133-42 20 Citations |
| 1 | The Pitx2 protein in mouse development. (Hjalt TA, Semina EV, Amendt BA, Murray JC) Dev Dyn 2000 May;218(1):195-200 123 Citations |
| 1 | Ligand-specific selection of MHC class II-restricted thymocytes in fetal thymic organ culture. (Kersh GJ, Engle DL, Williams CB, Allen PM) J Immunol 2000 Jun 01;164(11):5675-82 10 Citations |
| 1 | Withania somnifera root extract in the regulation of lead-induced oxidative damage in male mouse. (Chaurasia SS, Panda S, Kar A) Pharmacol Res 2000 Jun;41(6):663-6 50 Citations |
| 1 | Rho small G-protein-dependent binding of mDia to an Src homology 3 domain-containing IRSp53/BAIAP2. (Fujiwara T, Mammoto A, Kim Y, Takai Y) Biochem Biophys Res Commun 2000 May 19;271(3):626-9 71 Citations |
| 1 | Epidermal growth factor receptor blockade with C225 plus gemcitabine results in regression of human pancreatic carcinoma growing orthotopically in nude mice by antiangiogenic mechanisms. (Bruns CJ, Harbison MT, Davis DW, Portera CA, Tsan R, McConkey DJ, Evans DB, Abbruzzese JL, Hicklin DJ, Radinsky R) Clin Cancer Res 2000 May;6(5):1936-48 427 Citations |
| 1 | Clonal diversification of primary BALB/c plasmacytomas harboring T(12;15) chromosomal translocations. (Kovalchuk AL, Mushinski EB, Janz S) Leukemia 2000 May;14(5):909-21 18 Citations |
| 1 | Expression of a constitutively active form of phosphatidylinositol 3-kinase inhibits the induction of nitric oxide synthase in human astrocytes. (Pahan K, Liu X, Wood C, Raymond JR) FEBS Lett 2000 Apr 28;472(2-3):203-7 32 Citations |
| 1 | Induction of CD36 expression by oxidized LDL and IL-4 by a common signaling pathway dependent on protein kinase C and PPAR-gamma. (Feng J, Han J, Pearce SF, Silverstein RL, Gotto AM Jr, Hajjar DP, Nicholson AC) J Lipid Res 2000 May;41(5):688-96 228 Citations |
| 1 | CD28-specific antibody prevents graft-versus-host disease in mice. (Yu XZ, Bidwell SJ, Martin PJ, Anasetti C) J Immunol 2000 May 01;164(9):4564-8 79 Citations |
| 2 | New target regions for human hypertension via comparative genomics. (Stoll M, Kwitek-Black AE, Cowley AW Jr, Harris EL, Harrap SB, Krieger JE, Printz MP, Provoost AP, Sassard J, Jacob HJ) Genome Res 2000 Apr;10(4):473-82 201 Citations |
| 1 | Anxiety in a transgenic mouse model of cortical-limbic neuro-potentiated compulsive behavior. (McGrath MJ, Campbell KM, Veldman MB, Burton FH) Behav Pharmacol 1999 Sep;10(5):435-43 44 Citations |
| 1 | Macrophage scavenger receptor CD36 is the major receptor for LDL modified by monocyte-generated reactive nitrogen species. (Podrez EA, Febbraio M, Sheibani N, Schmitt D, Silverstein RL, Hajjar DP, Cohen PA, Frazier WA, Hoff HF, Hazen SL) J Clin Invest 2000 Apr;105(8):1095-108 389 Citations |
| 1 | Targeted disruption of the class B scavenger receptor CD36 protects against atherosclerotic lesion development in mice. (Febbraio M, Podrez EA, Smith JD, Hajjar DP, Hazen SL, Hoff HF, Sharma K, Silverstein RL) J Clin Invest 2000 Apr;105(8):1049-56 888 Citations |
| 1 | Single repeat deletion in ApoA-I blocks cholesterol esterification and results in rapid catabolism of delta6 and wild-type ApoA-I in transgenic mice. (Sorci-Thomas MG, Thomas M, Curtiss L, Landrum M) J Biol Chem 2000 Apr 21;275(16):12156-63 43 Citations |
| 1 | Targeted overactivity of beta cell K(ATP) channels induces profound neonatal diabetes. (Koster JC, Marshall BA, Ensor N, Corbett JA, Nichols CG) Cell 2000 Mar 17;100(6):645-54 258 Citations |
| 1 | Understanding hypertension through genetic manipulation in mice. (Cvetkovic B, Sigmund CD) Kidney Int 2000 Mar;57(3):863-74 39 Citations |
| 1 | TGF-beta 2 reduces demyelination, virus antigen expression, and macrophage recruitment in a viral model of multiple sclerosis. (Drescher KM, Murray PD, Lin X, Carlino JA, Rodriguez M) J Immunol 2000 Mar 15;164(6):3207-13 34 Citations |
| 1 | Contrasting blood pressure effects of obesity in leptin-deficient ob/ob mice and agouti yellow obese mice. (Mark AL, Shaffer RA, Correia ML, Morgan DA, Sigmund CD, Haynes WG) J Hypertens 1999 Dec;17(12 Pt 2):1949-53 237 Citations |
| 1 | Impaired endothelial function in transgenic mice expressing both human renin and human angiotensinogen. (Didion SP, Sigmund CD, Faraci FM) Stroke 2000 Mar;31(3):760-4; discussion 765 54 Citations |
| 1 | Identification of cis elements in the cardiac troponin T gene conferring specific expression in cardiac muscle of transgenic mice. (Wang Q, Sigmund CD, Lin JJ) Circ Res 2000 Mar 03;86(4):478-84 28 Citations |
| 1 | Axonal loss results in spinal cord atrophy, electrophysiological abnormalities and neurological deficits following demyelination in a chronic inflammatory model of multiple sclerosis. (McGavern DB, Murray PD, Rivera-Quiñones C, Schmelzer JD, Low PA, Rodriguez M) Brain 2000 Mar;123 Pt 3(Pt 3):519-31 119 Citations |
| 1 | Isolation and characterization of a novel human paired-like homeodomain-containing transcription factor gene, VSX1, expressed in ocular tissues. (Semina EV, Mintz-Hittner HA, Murray JC) Genomics 2000 Jan 15;63(2):289-93 76 Citations |
| 1 | Transgenic models as tools for studying the regulation of human renin expression. (Sinn PL, Sigmund CD) Regul Pept 2000 Jan 29;86(1-3):77-82 9 Citations |
| 2 | Effect of molecular structure on the performance of triarylmethane dyes as therapeutic agents for photochemical purging of autologous bone marrow grafts from residual tumor cells. (Indig GL, Anderson GS, Nichols MG, Bartlett JA, Mellon WS, Sieber F) J Pharm Sci 2000 Jan;89(1):88-99 72 Citations |
| 1 | Enhancement of susceptibility to Fas-mediated apoptosis of TH1 cells by nonmitogenic anti-CD3epsilon F(ab')2. (Yu XZ, Anasetti C) Transplantation 2000 Jan 15;69(1):104-12 16 Citations |
| 1 | An early developmental transcription factor complex that is more stable on nucleosome core particles than on free DNA. (Cirillo LA, Zaret KS) Mol Cell 1999 Dec;4(6):961-9 197 Citations |
| 1 | Antagonistic signals between BMP4 and FGF8 define the expression of Pitx1 and Pitx2 in mouse tooth-forming anlage. (St Amand TR, Zhang Y, Semina EV, Zhao X, Hu Y, Nguyen L, Murray JC, Chen Y) Dev Biol 2000 Jan 15;217(2):323-32 177 Citations |
| 1 | Appropriate tissue- and cell-specific expression of a single copy human angiotensinogen transgene specifically targeted upstream of the HPRT locus by homologous recombination. (Cvetkovic B, Yang B, Williamson RA, Sigmund CD) J Biol Chem 2000 Jan 14;275(2):1073-8 43 Citations |
| 1 | Canstatin, a novel matrix-derived inhibitor of angiogenesis and tumor growth. (Kamphaus GD, Colorado PC, Panka DJ, Hopfer H, Ramchandran R, Torre A, Maeshima Y, Mier JW, Sukhatme VP, Kalluri R) J Biol Chem 2000 Jan 14;275(2):1209-15 431 Citations |
| 1 | Murine CCR9, a chemokine receptor for thymus-expressed chemokine that is up-regulated following pre-TCR signaling. (Norment AM, Bogatzki LY, Gantner BN, Bevan MJ) J Immunol 2000 Jan 15;164(2):639-48 95 Citations |
| 1 | Reference memory, anxiety and estrous cyclicity in C57BL/6NIA mice are affected by age and sex. (Frick KM, Burlingame LA, Arters JA, Berger-Sweeney J) Neuroscience 2000;95(1):293-307 224 Citations |
| 1 | Treatment of polycystic kidney disease with a novel tyrosine kinase inhibitor. (Sweeney WE, Chen Y, Nakanishi K, Frost P, Avner ED) Kidney Int 2000 Jan;57(1):33-40 199 Citations |
| 1 | A critical role for neutrophil elastase in experimental bullous pemphigoid. (Liu Z, Shapiro SD, Zhou X, Twining SS, Senior RM, Giudice GJ, Fairley JA, Diaz LA) J Clin Invest 2000 Jan;105(1):113-23 173 Citations |
| 1 | Primary megakaryocytes reveal a role for transcription factor NF-E2 in integrin alpha IIb beta 3 signaling. (Shiraga M, Ritchie A, Aidoudi S, Baron V, Wilcox D, White G, Ybarrondo B, Murphy G, Leavitt A, Shattil S) J Cell Biol 1999 Dec 27;147(7):1419-30 78 Citations |
| 1 | Signals leading to apoptosis-dependent inhibition of neovascularization by thrombospondin-1. (Jiménez B, Volpert OV, Crawford SE, Febbraio M, Silverstein RL, Bouck N) Nat Med 2000 Jan;6(1):41-8 910 Citations |
| 1 | IL-12 is produced by antigen-presenting cells stimulated with soluble alphabeta TCR and restores impaired T(h)1 responses. (Kawamoto K, Paliwal V, Ramabhadran R, Szczepanik M, Tsuji RF, Matsuda H, Askenase PW) Int Immunol 2000 Jan;12(1):103-12 7 Citations |
| 1 | Restrained chondrocyte proliferation and maturation with abnormal growth plate vascularization and ossification in human FGFR-3(G380R) transgenic mice. (Segev O, Chumakov I, Nevo Z, Givol D, Madar-Shapiro L, Sheinin Y, Weinreb M, Yayon A) Hum Mol Genet 2000 Jan 22;9(2):249-58 93 Citations |
| 1 | Expression of the SRF gene occurs through a Ras/Sp/SRF-mediated-mechanism in response to serum growth signals. (Spencer JA, Misra RP) Oncogene 1999 Dec 02;18(51):7319-27 39 Citations |
| 1 | Vascular biology in genetically altered mice : smaller vessels, bigger insight. (Faraci FM, Sigmund CD) Circ Res 1999 Dec 3-17;85(12):1214-25 71 Citations |
| 1 | Highly regulated cell type-restricted expression of human renin in mice containing 140- or 160-kilobase pair P1 phage artificial chromosome transgenes. (Sinn PL, Davis DR, Sigmund CD) J Biol Chem 1999 Dec 10;274(50):35785-93 52 Citations |
| 1 | Role of immunoregulatory donor T cells in suppression of graft-versus-host disease following donor leukocyte infusion therapy. (Johnson BD, Becker EE, LaBelle JL, Truitt RL) J Immunol 1999 Dec 15;163(12):6479-87 63 Citations |
| 1 | Postnatal loss of Merkel cells, but not of slowly adapting mechanoreceptors in mice lacking the neurotrophin receptor p75. (Kinkelin I, Stucky CL, Koltzenburg M) Eur J Neurosci 1999 Nov;11(11):3963-9 44 Citations |
| 1 | Analysis of the AU-rich elements in the 3'-untranslated region of beta 2-adrenergic receptor mRNA by mutagenesis and identification of the homologous AU-rich region from different species. (Tholanikunnel BG, Raymond JR, Malbon CC) Biochemistry 1999 Nov 23;38(47):15564-72 24 Citations |
| 1 | Glomerulosclerosis and hypoplasia--a common theme? (Avner ED) Kidney Int 1999 Nov;56(5):1962-3 3 Citations |
| 1 | The Ets factors PU.1 and Spi-B regulate the transcription in vivo of P2Y10, a lymphoid restricted heptahelical receptor. (Rao S, Garrett-Sinha LA, Yoon J, Simon MC) J Biol Chem 1999 Nov 26;274(48):34245-52 34 Citations |
| 1 | Forced expression of the leukemia-associated gene EVI1 in ES cells: a model for myeloid leukemia with 3q26 rearrangements. (Sitailo S, Sood R, Barton K, Nucifora G) Leukemia 1999 Nov;13(11):1639-45 65 Citations |
| 1 | Singlet oxygen adducts of cholesterol: photogeneration and reductive turnover in membrane systems. (Korytowski W, Girotti AW) Photochem Photobiol 1999 Oct;70(4):484-9 53 Citations |
| 1 | HSF1 is required for extra-embryonic development, postnatal growth and protection during inflammatory responses in mice. (Xiao X, Zuo X, Davis AA, McMillan DR, Curry BB, Richardson JA, Benjamin IJ) EMBO J 1999 Nov 01;18(21):5943-52 472 Citations |
| 1 | Cellular pathophysiology of cystic kidney disease: insight into future therapies. (Avner ED, Woychik RP, Dell KM, Sweeney WE) Int J Dev Biol 1999;43(5):457-61 12 Citations |
| 1 | Quantitation of spinal cord demyelination, remyelination, atrophy, and axonal loss in a model of progressive neurologic injury. (McGavern DB, Murray PD, Rodriguez M) J Neurosci Res 1999 Nov 15;58(4):492-504 76 Citations |
| 1 | Visualization, fate, and pathogenicity of antigen-specific CD8+ T cells in the graft-versus-host reaction. (Yu XZ, Bidwell S, Martin PJ, Anasetti C) J Immunol 1999 Nov 01;163(9):4780-7 14 Citations |
| 1 | Photochemical treatment with S-59 psoralen and ultraviolet A light to control the fate of naive or primed T lymphocytes in vivo after allogeneic bone marrow transplantation. (Truitt RL, Johnson BD, Hanke C, Talib S, Hearst JE) J Immunol 1999 Nov 01;163(9):5145-56 48 Citations |
| 1 | JG cell expression and partial regulation of a human renin genomic transgene driven by a minimal renin promoter. (Sinn PL, Zhang X, Sigmund CD) Am J Physiol 1999 Oct;277(4):F634-42 19 Citations |
| 1 | Cytogenetic analysis of the bipotential murine pre-B cell lymphoma, P388, and its derivative macrophage-like tumor, P388D1, using SKY and CGH. (Coleman AE, Forest ST, McNeil N, Kovalchuk AL, Ried T, Janz S) Leukemia 1999 Oct;13(10):1592-600 15 Citations |
| 1 | Quantitative studies on the respiratory burst generated in peritoneal macrophages. (Kriska T, Gamaley I, Vasvári G, Holly S, Maltseva E, Strizhak P, Gál D) J Photochem Photobiol B 1999 Jun;50(2-3):159-65 3 Citations |
| 1 | Prolonged STAT1 activation is associated with interferon-gamma priming for interleukin-1-induced inducible nitric-oxide synthase expression by islets of Langerhans. (Heitmeier MR, Scarim AL, Corbett JA) J Biol Chem 1999 Oct 08;274(41):29266-73 67 Citations |
| 1 | Influence of J series prostaglandins on apoptosis and tumorigenesis of breast cancer cells. (Clay CE, Namen AM, Atsumi G, Willingham MC, High KP, Kute TE, Trimboli AJ, Fonteh AN, Dawson PA, Chilton FH) Carcinogenesis 1999 Oct;20(10):1905-11 172 Citations |
| 1 | Overexpression of nerve growth factor in skin selectively affects the survival and functional properties of nociceptors. (Stucky CL, Koltzenburg M, Schneider M, Engle MG, Albers KM, Davis BM) J Neurosci 1999 Oct 01;19(19):8509-16 99 Citations |
| 1 | Species-specific differences in positive and negative regulatory elements in the renin gene enhancer. (Shi Q, Black TA, Gross KW, Sigmund CD) Circ Res 1999 Sep 17;85(6):479-88 44 Citations |
| 1 | Cloning and preliminary characterization of a calcium-binding protein closely related to nucleolin on the apical surface of inner medullary collecting duct cells. (Sorokina EA, Kleinman JG) J Biol Chem 1999 Sep 24;274(39):27491-6 38 Citations |
| 1 | E1A oncogene induction of cellular susceptibility to killing by cytolytic lymphocytes through target cell sensitization to apoptotic injury. (Cook JL, Routes BA, Walker TA, Colvin KL, Routes JM) Exp Cell Res 1999 Sep 15;251(2):414-23 19 Citations |
| 1 | Circulating alpha-galactosidase A derived from transduced bone marrow cells: relevance for corrective gene transfer for Fabry disease. (Takenaka T, Qin G, Brady RO, Medin JA) Hum Gene Ther 1999 Aug 10;10(12):1931-9 46 Citations |
| 1 | Graft-facilitating doses of ex vivo activated gammadelta T cells do not cause lethal murine graft-vs.-host disease. (Drobyski WR, Majewski D, Hanson G) Biol Blood Marrow Transplant 1999;5(4):222-30 62 Citations |
| 1 | Angiogenesis and atherosclerosis. The mandate broadens. (Silverstein RL, Nachman RL) Circulation 1999 Aug 24;100(8):783-5 21 Citations |
| 1 | Elevated mutant frequencies in lymphoid tissues persist throughout plasmacytoma development in BALB/c.lambdaLIZ mice. (Felix K, Kelliher KA, Bornkamm GW, Janz S) Cancer Res 1999 Aug 01;59(15):3621-6 10 Citations |
| 1 | Gene transfer of endothelial nitric oxide synthase (eNOS) in eNOS-deficient mice. (Lake-Bruse KD, Faraci FM, Shesely EG, Maeda N, Sigmund CD, Heistad DD) Am J Physiol 1999 Aug;277(2):H770-6 52 Citations |
| 1 | Neutrophil chemokine production in the skin following scald injury. (Faunce DE, Llanas JN, Patel PJ, Gregory MS, Duffner LA, Kovacs EJ) Burns 1999 Aug;25(5):403-10 75 Citations |
| 1 | In vitro modulation of cyst formation by a novel tyrosine kinase inhibitor. (Sweeney WE, Futey L, Frost P, Avner ED) Kidney Int 1999 Aug;56(2):406-13 45 Citations |
| 1 | Dysregulated myelopoiesis in mice lacking Jak3. (Grossman WJ, Verbsky JW, Yang L, Berg LJ, Fields LE, Chaplin DD, Ratner L) Blood 1999 Aug 01;94(3):932-9 42 Citations |
| 1 | Chemokine receptor expression by human intestinal epithelial cells. (Dwinell MB, Eckmann L, Leopard JD, Varki NM, Kagnoff MF) Gastroenterology 1999 Aug;117(2):359-67 186 Citations |
| 1 | Evidence that beta cell death in the nonobese diabetic mouse is Fas independent. (Thomas HE, Darwiche R, Corbett JA, Kay TW) J Immunol 1999 Aug 01;163(3):1562-9 108 Citations |
| 1 | Isolectin B(4)-positive and -negative nociceptors are functionally distinct. (Stucky CL, Lewin GR) J Neurosci 1999 Aug 01;19(15):6497-505 400 Citations |
| 1 | Efficient liver-specific deletion of a floxed human angiotensinogen transgene by adenoviral delivery of Cre recombinase in vivo. (Stec DE, Davisson RL, Haskell RE, Davidson BL, Sigmund CD) J Biol Chem 1999 Jul 23;274(30):21285-90 74 Citations |
| 1 | Presentation of out-of-frame peptide/MHC class I complexes by a novel translation initiation mechanism. (Malarkannan S, Horng T, Shih PP, Schwab S, Shastri N) Immunity 1999 Jun;10(6):681-90 94 Citations |
| 1 | A high-density integrated genetic linkage and radiation hybrid map of the laboratory rat. (Steen RG, Kwitek-Black AE, Glenn C, Gullings-Handley J, Van Etten W, Atkinson OS, Appel D, Twigger S, Muir M, Mull T, Granados M, Kissebah M, Russo K, Crane R, Popp M, Peden M, Matise T, Brown DM, Lu J, Kingsmore S, Tonellato PJ, Rozen S, Slonim D, Young P, Jacob HJ) Genome Res 1999 Jun;9(6):AP1-8, insert 186 Citations |
| 1 | Transgenic shuttle vector assays for assessing oxidative B-cell mutagenesis in vivo. (Felix K, Kelliher K, Bornkamm GW, Janz S) Curr Top Microbiol Immunol 1999;246:369-75; discussion 376-7 |
| 1 | Recurrent non-reciprocal translocations of chromosome 5 in primary T(12;15)-positive BALB/c plasmacytomas. (Coleman AE, Ried T, Janz S) Curr Top Microbiol Immunol 1999;246:175-80; discussion 181 4 Citations |
| 1 | Graft-vs.-host and graft-vs.-leukemia reactions after delayed infusions of donor T-subsets. (Johnson BD, Becker EE, Truitt RL) Biol Blood Marrow Transplant 1999;5(3):123-32 54 Citations |
| 1 | Jumping translocation breakpoint regions lead to amplification of rearranged Myc. (Coleman AE, Kovalchuk AL, Janz S, Palini A, Ried T) Blood 1999 Jun 15;93(12):4442-4 11 Citations |
| 1 | Enzymatic and functional correction along with long-term enzyme secretion from transduced bone marrow hematopoietic stem/progenitor and stromal cells derived from patients with Fabry disease. (Takenaka T, Hendrickson CS, Tworek DM, Tudor M, Schiffmann R, Brady RO, Medin JA) Exp Hematol 1999 Jul;27(7):1149-59 39 Citations |
| 1 | Stomatin, a MEC-2 like protein, is expressed by mammalian sensory neurons. (Mannsfeldt AG, Carroll P, Stucky CL, Lewin GR) Mol Cell Neurosci 1999 Jun;13(6):391-404 60 Citations |
| 1 | A null mutation in murine CD36 reveals an important role in fatty acid and lipoprotein metabolism. (Febbraio M, Abumrad NA, Hajjar DP, Sharma K, Cheng W, Pearce SF, Silverstein RL) J Biol Chem 1999 Jul 02;274(27):19055-62 680 Citations |
| 1 | Overexpression of protein kinase C-alpha in MCF-7 breast cancer cells results in differential regulation and expression of alphavbeta3 and alphavbeta5. (Carey I, Williams CL, Ways DK, Noti JD) Int J Oncol 1999 Jul;15(1):127-36 22 Citations |
| 1 | Collaborative role of E2F transcriptional activity and G1 cyclindependent kinase activity in the induction of S phase. (Leone G, DeGregori J, Jakoi L, Cook JG, Nevins JR) Proc Natl Acad Sci U S A 1999 Jun 08;96(12):6626-31 77 Citations |
| 1 | Elevation in pulmonary neutrophils and prolonged production of pulmonary macrophage inflammatory protein-2 after burn injury with prior alcohol exposure. (Patel PJ, Faunce DE, Gregory MS, Duffner LA, Kovacs EJ) Am J Respir Cell Mol Biol 1999 Jun;20(6):1229-37 49 Citations |
| 2 | Macrophages and epithelial cells respond differently to the Pseudomonas aeruginosa type III secretion system. (Coburn J, Frank DW) Infect Immun 1999 Jun;67(6):3151-4 65 Citations |
| 2 | Synthesis and characterization of potent and selective agonists of the neuronal cannabinoid receptor (CB1). (Hillard CJ, Manna S, Greenberg MJ, DiCamelli R, Ross RA, Stevenson LA, Murphy V, Pertwee RG, Campbell WB) J Pharmacol Exp Ther 1999 Jun;289(3):1427-33 331 Citations |
| 1 | A kinetic threshold between negative and positive selection based on the longevity of the T cell receptor-ligand complex. (Williams CB, Engle DL, Kersh GJ, Michael White J, Allen PM) J Exp Med 1999 May 17;189(10):1531-44 98 Citations |
| 1 | Kringle 5 causes cell cycle arrest and apoptosis of endothelial cells. (Lu H, Dhanabal M, Volk R, Waterman MJ, Ramchandran R, Knebelmann B, Segal M, Sukhatme VP) Biochem Biophys Res Commun 1999 May 19;258(3):668-73 73 Citations |
| 1 | Radiolabeled cholesterol as a reporter for assessing one-electron turnover of lipid hydroperoxides. (Korytowski W, Wrona M, Girotti AW) Anal Biochem 1999 May 15;270(1):123-32 48 Citations |
| 1 | Basic fibroblast growth factor activates serum response factor gene expression by multiple distinct signaling mechanisms. (Spencer JA, Major ML, Misra RP) Mol Cell Biol 1999 Jun;19(6):3977-88 21 Citations |
| 1 | In vivo gene therapy with interleukin-12 inhibits primary vascular tumor growth and induces apoptosis in a mouse model. (Wang C, Quevedo ME, Lannutti BJ, Gordon KB, Guo D, Sun W, Paller AS) J Invest Dermatol 1999 May;112(5):775-81 32 Citations |
| 1 | Cutting edge: the tyrosine phosphatase SHP-1 regulates thymocyte positive selection. (Plas DR, Williams CB, Kersh GJ, White LS, White JM, Paust S, Ulyanova T, Allen PM, Thomas ML) J Immunol 1999 May 15;162(10):5680-4 47 Citations |
| 1 | PU.1 and Spi-B are required for normal B cell receptor-mediated signal transduction. (Garrett-Sinha LA, Su GH, Rao S, Kabak S, Hao Z, Clark MR, Simon MC) Immunity 1999 Apr;10(4):399-408 100 Citations |
| 1 | A new paradigm of T cell allergy: requirement for the B-1 cell subset. (Askenase PW, Kawikova I, Paliwal V, Akahira-Azuma M, Gerard C, Hugli T, Tsuji R) Int Arch Allergy Immunol 1999;118(2-4):145-9 22 Citations |
| 1 | Migration and ultrastructural localization of the c-kit receptor protein in spermatogenic cells and spermatozoa of the mouse. (Sandlow JI, Feng HL, Zheng LJ, Sandra A) J Urol 1999 May;161(5):1676-80 23 Citations |
| 1 | Endostatin induces endothelial cell apoptosis. (Dhanabal M, Ramchandran R, Waterman MJ, Lu H, Knebelmann B, Segal M, Sukhatme VP) J Biol Chem 1999 Apr 23;274(17):11721-6 592 Citations |
| 1 | Active and passive immunization with the Pseudomonas V antigen protects against type III intoxication and lung injury. (Sawa T, Yahr TL, Ohara M, Kurahashi K, Gropper MA, Wiener-Kronish JP, Frank DW) Nat Med 1999 Apr;5(4):392-8 309 Citations |
| 1 | SPI-B activates transcription via a unique proline, serine, and threonine domain and exhibits DNA binding affinity differences from PU.1. (Rao S, Matsumura A, Yoon J, Simon MC) J Biol Chem 1999 Apr 16;274(16):11115-24 45 Citations |
| 1 | Protoporphyrin IX-sensitized photoinactivation of 5-aminolevulinate-treated leukemia cells: effects of exogenous iron. (Lin F, Geiger PG, Korytowski W, Girotti AW) Photochem Photobiol 1999 Mar;69(3):375-81 10 Citations |
| 1 | Characterization of monoclonal antibodies against hepatitis C virus nonstructural protein 3: different antigenic determinants from human B cells. (Ou-Yang P, Chiang BL, Hwang LH, Chen YG, Yang PM, Chi WK, Chen PJ, Chen DS) J Med Virol 1999 Apr;57(4):345-50 7 Citations |
| 1 | Chronic administration of propranolol impairs inhibitory avoidance retention in mice. (Nielson KA, Czech DA, Laubmeier KK) Neurobiol Learn Mem 1999 Mar;71(2):248-57 21 Citations |
| 2 | Physico-chemical modeling of the role of free radicals in photodynamic therapy. IV. Quantitative aspects of photodynamic effects on free radicals generated in cell cultures. (Németh A, Jakus J, Kriska T, Keszler A, Vanyur R, Gál D) Biochem Biophys Res Commun 1999 Feb 16;255(2):360-6 11 Citations |
| 1 | CNS cell populations are protected from virus-induced pathology by distinct arms of the immune system. (Drescher KM, Murray PD, David CS, Pease LR, Rodriguez M) Brain Pathol 1999 Jan;9(1):21-31 24 Citations |
| 1 | Absence of spontaneous central nervous system remyelination in class II-deficient mice infected with Theiler's virus. (Njenga MK, Murray PD, McGavern D, Lin X, Drescher KM, Rodriguez M) J Neuropathol Exp Neurol 1999 Jan;58(1):78-91 31 Citations |
| 1 | Three distinct D-amino acid substitutions confer potent antiangiogenic activity on an inactive peptide derived from a thrombospondin-1 type 1 repeat. (Dawson DW, Volpert OV, Pearce SF, Schneider AJ, Silverstein RL, Henkin J, Bouck NP) Mol Pharmacol 1999 Feb;55(2):332-8 139 Citations |
| 1 | Endostatin: yeast production, mutants, and antitumor effect in renal cell carcinoma. (Dhanabal M, Ramchandran R, Volk R, Stillman IE, Lombardo M, Iruela-Arispe ML, Simons M, Sukhatme VP) Cancer Res 1999 Jan 01;59(1):189-97 261 Citations |
| 1 | The angiotensinogen gene is expressed in both astrocytes and neurons in murine central nervous system. (Yang G, Gray TS, Sigmund CD, Cassell MD) Brain Res 1999 Jan 30;817(1-2):123-31 85 Citations |
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| 1 | RGS3 inhibits G protein-mediated signaling via translocation to the membrane and binding to Galpha11. (Dulin NO, Sorokin A, Reed E, Elliott S, Kehrl JH, Dunn MJ) Mol Cell Biol 1999 Jan;19(1):714-23 97 Citations |
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| 1 | Morphological and functional characterization of a conditionally immortalized collecting tubule cell line. (Takacs-Jarrett M, Sweeney WE, Avner ED, Cotton CU) Am J Physiol 1998 Nov;275(5):F802-11 22 Citations |
| 1 | The brain renin-angiotensin system contributes to the hypertension in mice containing both the human renin and human angiotensinogen transgenes. (Davisson RL, Yang G, Beltz TG, Cassell MD, Johnson AK, Sigmund CD) Circ Res 1998 Nov 16;83(10):1047-58 131 Citations |
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| 1 | Sca1(+)/Mac1(+) nitric oxide-producing cells in the spleens of recipients early following bone marrow transplant suppress T cell responses in vitro. (Johnson BD, Hanke CA, Becker EE, Truitt RL) Cell Immunol 1998 Nov 01;189(2):149-59 12 Citations |
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| 1 | The study of self-tolerance using murine haemoglobin as a model self antigen. (Williams CB, Allen PM) Novartis Found Symp 1998;215:41-6; discussion 46-53 2 Citations |
| 1 | The molecular and functional characterization of a dominant minor H antigen, H60. (Malarkannan S, Shih PP, Eden PA, Horng T, Zuberi AR, Christianson G, Roopenian D, Shastri N) J Immunol 1998 Oct 01;161(7):3501-9 212 Citations |
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| 1 | Point mutation in trkB causes loss of NT4-dependent neurons without major effects on diverse BDNF responses. (Minichiello L, Casagranda F, Tatche RS, Stucky CL, Postigo A, Lewin GR, Davies AM, Klein R) Neuron 1998 Aug;21(2):335-45 165 Citations |
| 1 | Ex vivo anti-CD3 antibody-activated donor T cells have a reduced ability to cause lethal murine graft-versus-host disease but retain their ability to facilitate alloengraftment. (Drobyski WR, Majewski D, Ozker K, Hanson G) J Immunol 1998 Sep 01;161(5):2610-9 46 Citations |
| 1 | Pitx2, a bicoid-type homeobox gene, is involved in a lefty-signaling pathway in determination of left-right asymmetry. (Yoshioka H, Meno C, Koshiba K, Sugihara M, Itoh H, Ishimaru Y, Inoue T, Ohuchi H, Semina EV, Murray JC, Hamada H, Noji S) Cell 1998 Aug 07;94(3):299-305 332 Citations |
| 1 | The two mannose 6-phosphate binding sites of the insulin-like growth factor-II/mannose 6-phosphate receptor display different ligand binding properties. (Marron-Terada PG, Brzycki-Wessell MA, Dahms NM) J Biol Chem 1998 Aug 28;273(35):22358-66 27 Citations |
| 1 | Neurotrophin 4 is required for the survival of a subclass of hair follicle receptors. (Stucky CL, DeChiara T, Lindsay RM, Yancopoulos GD, Koltzenburg M) J Neurosci 1998 Sep 01;18(17):7040-6 68 Citations |
| 1 | Species- and sex-related differences in metabolism of trichloroethylene to yield chloral and trichloroethanol in mouse, rat, and human liver microsomes. (Elfarra AA, Krause RJ, Last AR, Lash LH, Parker JC) Drug Metab Dispos 1998 Aug;26(8):779-85 37 Citations |
| 1 | CD4(+) and CD8(+) T cells make discrete contributions to demyelination and neurologic disease in a viral model of multiple sclerosis. (Murray PD, Pavelko KD, Leibowitz J, Lin X, Rodriguez M) J Virol 1998 Sep;72(9):7320-9 111 Citations |
| 1 | In vivo expression of a TCR antagonist: T cells escape central tolerance but are antagonized in the periphery. (Williams CB, Vidal K, Donermeyer D, Peterson DA, White JM, Allen PM) J Immunol 1998 Jul 01;161(1):128-37 30 Citations |
| 1 | Silicone gel enhances the development of autoimmune disease in New Zealand black mice but fails to induce it in BALB/cAnPt mice. (McDonald AH, Weir K, Schneider M, Gudenkauf L, Sanger JR) Clin Immunol Immunopathol 1998 Jun;87(3):248-55 28 Citations |
| 1 | Cytotoxicity of endodontic materials. (Osorio RM, Hefti A, Vertucci FJ, Shawley AL) J Endod 1998 Feb;24(2):91-6 176 Citations |
| 2 | In vitro cellular toxicity predicts Pseudomonas aeruginosa virulence in lung infections. (Sawa T, Ohara M, Kurahashi K, Twining SS, Frank DW, Doroques DB, Long T, Gropper MA, Wiener-Kronish JP) Infect Immun 1998 Jul;66(7):3242-9 104 Citations |
| 1 | Crk protein binds to PDGF receptor and insulin receptor substrate-1 with different modulating effects on PDGF- and insulin-dependent signaling pathways. (Sorokin A, Reed E, Nnkemere N, Dulin NO, Schlessinger J) Oncogene 1998 May 14;16(19):2425-34 17 Citations |
| 1 | Double-stranded RNA-induced inducible nitric-oxide synthase expression and interleukin-1 release by murine macrophages requires NF-kappaB activation. (Heitmeier MR, Scarim AL, Corbett JA) J Biol Chem 1998 Jun 12;273(24):15301-7 100 Citations |
| 1 | A novel homeobox gene PITX3 is mutated in families with autosomal-dominant cataracts and ASMD. (Semina EV, Ferrell RE, Mintz-Hittner HA, Bitoun P, Alward WL, Reiter RS, Funkhauser C, Daack-Hirsch S, Murray JC) Nat Genet 1998 Jun;19(2):167-70 346 Citations |
| 1 | Developmental expression of human angiotensinogen in transgenic mice. (Yang G, Sigmund CD) Am J Physiol 1998 May;274(5):F932-9 13 Citations |
| 1 | Theiler's virus infection of genetically susceptible mice induces central nervous system-infiltrating CTLs with no apparent viral or major myelin antigenic specificity. (Lin X, Pease LR, Murray PD, Rodriguez M) J Immunol 1998 Jun 01;160(11):5661-8 32 Citations |
| 1 | Cloning and chromosomal mapping of the murine norepinephrine transporter. (Fritz JD, Jayanthi LD, Thoreson MA, Blakely RD) J Neurochem 1998 Jun;70(6):2241-51 46 Citations |
| 1 | The role of hepatocyte growth factor (HGF) at progressive stages of metanephric development. (Sweeney WE Jr, Avner ED) In Vitro Cell Dev Biol Anim 1998 Feb;34(2):189-94 2 Citations |
| 1 | Collagenase 1 and collagenase 3 expression in a guinea pig model of osteoarthritis. (Huebner JL, Otterness IG, Freund EM, Caterson B, Kraus VB) Arthritis Rheum 1998 May;41(5):877-90 96 Citations |
| 1 | Presentation of proteolipid protein epitopes and B7-1-dependent activation of encephalitogenic T cells by IFN-gamma-activated SJL/J astrocytes. (Tan L, Gordon KB, Mueller JP, Matis LA, Miller SD) J Immunol 1998 May 01;160(9):4271-9 107 Citations |
| 1 | Cdc6 is regulated by E2F and is essential for DNA replication in mammalian cells. (Yan Z, DeGregori J, Shohet R, Leone G, Stillman B, Nevins JR, Williams RS) Proc Natl Acad Sci U S A 1998 Mar 31;95(7):3603-8 222 Citations |
| 1 | Association of elevated mutagenesis in the spleen with genetic susceptibility to induced plasmacytoma development in mice. (Felix K, Kelliher K, Bornkamm GW, Janz S) Cancer Res 1998 Apr 15;58(8):1616-9 4 Citations |
| 1 | Reduced fertility in female mice lacking copper-zinc superoxide dismutase. (Ho YS, Gargano M, Cao J, Bronson RT, Heimler I, Hutz RJ) J Biol Chem 1998 Mar 27;273(13):7765-9 288 Citations |
| 1 | Targeted disruption of heat shock transcription factor 1 abolishes thermotolerance and protection against heat-inducible apoptosis. (McMillan DR, Xiao X, Shao L, Graves K, Benjamin IJ) J Biol Chem 1998 Mar 27;273(13):7523-8 452 Citations |
| 1 | Characterization of the chimeric retinoic acid receptor RARalpha/VDR. (Pemrick SM, Abarzúa P, Kratzeisen C, Marks MS, Medin JA, Ozato K, Grippo JF) Leukemia 1998 Apr;12(4):554-62 6 Citations |
| 1 | A new human homeobox gene OGI2X is a member of the most conserved homeobox gene family and is expressed during heart development in mouse. (Semina EV, Reiter RS, Murray JC) Hum Mol Genet 1998 Mar;7(3):415-22 47 Citations |
| 1 | Epidermal growth factor receptor activity mediates renal cyst formation in polycystic kidney disease. (Richards WG, Sweeney WE, Yoder BK, Wilkinson JE, Woychik RP, Avner ED) J Clin Invest 1998 Mar 01;101(5):935-9 179 Citations |
| 1 | Glycosphingolipids as novel targets for T-cell suppression by the B subunit of recombinant heat-labile enterotoxin. (Truitt RL, Hanke C, Radke J, Mueller R, Barbieri JT) Infect Immun 1998 Apr;66(4):1299-308 35 Citations |
| 1 | Compensatory prostaglandin E2 biosynthesis in cyclooxygenase 1 or 2 null cells. (Kirtikara K, Morham SG, Raghow R, Laulederkind SJ, Kanekura T, Goorha S, Ballou LR) J Exp Med 1998 Feb 16;187(4):517-23 125 Citations |
| 1 | Cadmium decreases SGLT1 messenger RNA in mouse kidney cells. (Blumenthal SS, Ren L, Lewand DL, Krezoski SK, Petering DH) Toxicol Appl Pharmacol 1998 Mar;149(1):49-54 16 Citations |
| 1 | Aggregated immunoglobulin protects immune T cells from suppression: dependence on isotype, Fc portion, and macrophage FcgammaR. (Ptak W, Paliwal V, Bryniarski K, Ptak M, Askenase PW) Scand J Immunol 1998 Feb;47(2):136-45 13 Citations |
| 1 | Regulatory elements required for human angiotensinogen expression in HepG2 cells are dispensable in transgenic mice. (Yang G, Sigmund CD) Hypertension 1998 Mar;31(3):734-40 21 Citations |
| 1 | The c-kit receptor and its possible signaling transduction pathway in mouse spermatozoa. (Feng H, Sandlow JI, Sandra A) Mol Reprod Dev 1998 Mar;49(3):317-26 48 Citations |
| 1 | Responses of carotid artery in mice deficient in expression of the gene for endothelial NO synthase. (Faraci FM, Sigmund CD, Shesely EG, Maeda N, Heistad DD) Am J Physiol 1998 Feb;274(2):H564-70 119 Citations |
| 1 | Protective effects of vitamin E against lead-induced deterioration of membrane associated type-I iodothyronine 5'-monodeiodinase (5'D-I) activity in male mice. (Chaurasia SS, Kar A) Toxicology 1997 Dec 31;124(3):203-9 61 Citations |
| 1 | Binding of the winged-helix transcription factor HNF3 to a linker histone site on the nucleosome. (Cirillo LA, McPherson CE, Bossard P, Stevens K, Cherian S, Shim EY, Clark KL, Burley SK, Zaret KS) EMBO J 1998 Jan 02;17(1):244-54 329 Citations |
| 1 | Resistance to and recovery from lethal influenza virus infection in B lymphocyte-deficient mice. (Graham MB, Braciale TJ) J Exp Med 1997 Dec 15;186(12):2063-8 202 Citations |
| 1 | Isolation of a rat histidase cDNA sequence and expression in Escherichia coli--evidence of extrahepatic/epidermal distribution. (Sano H, Tada T, Moriyama A, Ogawa H, Asai K, Kawai Y, Hodgson ME, Kato T, Wada Y, Suchi M) Eur J Biochem 1997 Nov 15;250(1):212-21 11 Citations |
| 1 | Efficacy of taxol in the orpk mouse model of polycystic kidney disease. (Sommardahl CS, Woychik RP, Sweeney WE, Avner ED, Wilkinson JE) Pediatr Nephrol 1997 Dec;11(6):728-33 26 Citations |
| 1 | Mapping of the autosomal dominant cataract mutation (Coc) on mouse chromosome 16. (Sidjanin DJ, Grimes PA, Pretsch W, Neuhäuser-Klaus A, Favor J, Stambolian DE) Invest Ophthalmol Vis Sci 1997 Nov;38(12):2502-7 14 Citations |
| 1 | Influence of lead on type-I iodothyronine 5'-monodeiodinase activity in male mouse. (Chaurasia SS, Kar A) Horm Metab Res 1997 Oct;29(10):532-3 9 Citations |
| 1 | Use of transgenic and gene-targeted mice to model the genetic basis of hypertensive disorders. (Merrill DC, Granwehr BP, Davis DR, Sigmund CD) Proc Assoc Am Physicians 1997 Nov;109(6):533-46 11 Citations |
| 1 | Deletional remodeling of c-myc-deregulating chromosomal translocations. (Kovalchuk AL, Müller JR, Janz S) Oncogene 1997 Nov 06;15(19):2369-77 45 Citations |
| 1 | Isolation of a new homeobox gene belonging to the Pitx/Rieg family: expression during lens development and mapping to the aphakia region on mouse chromosome 19. (Semina EV, Reiter RS, Murray JC) Hum Mol Genet 1997 Nov;6(12):2109-16 173 Citations |
| 1 | Elevated ferritin production, iron containment, and oxidant resistance in hemin-treated leukemia cells. (Lin F, Girotti AW) Arch Biochem Biophys 1997 Oct 01;346(1):131-41 41 Citations |
| 1 | The kidney androgen-regulated protein promoter confers renal proximal tubule cell-specific and highly androgen-responsive expression on the human angiotensinogen gene in transgenic mice. (Ding Y, Davisson RL, Hardy DO, Zhu LJ, Merrill DC, Catterall JF, Sigmund CD) J Biol Chem 1997 Oct 31;272(44):28142-8 116 Citations |
| 1 | Elevated mutant frequencies in gene lacI in splenic lipopolysaccharide blasts after exposure to activated phagocytes in vitro. (Felix K, Lin S, Janz S) Eur J Immunol 1997 Sep;27(9):2160-4 5 Citations |
| 1 | Receptive properties of mouse sensory neurons innervating hairy skin. (Koltzenburg M, Stucky CL, Lewin GR) J Neurophysiol 1997 Oct;78(4):1841-50 304 Citations |
| 1 | Previously hidden chromosome aberrations in T(12;15)-positive BALB/c plasmacytomas uncovered by multicolor spectral karyotyping. (Coleman AE, Schröck E, Weaver Z, du Manoir S, Yang F, Ferguson-Smith MA, Ried T, Janz S) Cancer Res 1997 Oct 15;57(20):4585-92 40 Citations |
| 1 | Conserved enhancer elements in human and mouse renin genes have different transcriptional effects in As4.1 cells. (Yan Y, Jones CA, Sigmund CD, Gross KW, Catanzaro DF) Circ Res 1997 Oct;81(4):558-66 52 Citations |
| 1 | Recombinant soluble alphabeta T cell receptors protect T cells from immune suppression: requirement for aggregated multimeric, disulfide-linked alphabeta heterodimers. (Paliwal V, Ptak W, Sperl J, Braswell E, Askenase PW) J Immunol 1997 Aug 15;159(4):1718-27 4 Citations |
| 1 | ExoU expression by Pseudomonas aeruginosa correlates with acute cytotoxicity and epithelial injury. (Finck-Barbançon V, Goranson J, Zhu L, Sawa T, Wiener-Kronish JP, Fleiszig SM, Wu C, Mende-Mueller L, Frank DW) Mol Microbiol 1997 Aug;25(3):547-57 440 Citations |
| 1 | Downregulation of renin gene expression by interleukin-1. (Petrovic N, Kane CM, Sigmund CD, Gross KW) Hypertension 1997 Aug;30(2 Pt 1):230-5 25 Citations |
| 1 | Photochemical purging of autologous bone marrow grafts: assessment of damage to stem cells and the microenvironment in long-term marrow cultures. (Kubo Y, Sieber F) Bone Marrow Transplant 1997 Jul;20(1):27-31 9 Citations |
| 1 | Expression and function of the c-kit proto-oncogene protein in mouse sperm. (Feng H, Sandlow JI, Sandra A) Biol Reprod 1997 Jul;57(1):194-203 33 Citations |
| 1 | Role of cytoprotective mechanisms in the photochemical purging of autologous bone marrow grafts. (Yamazaki T, Sato Y, Sieber F) Exp Hematol 1997 Jul;25(7):629-37 21 Citations |
| 1 | Involvement of a sperm protein sensitive to sulfhydryl-depleting reagents in mouse sperm-egg fusion. (Mammoto A, Masumoto N, Tahara M, Yoneda M, Nishizaki T, Tasaka K, Miyake A) J Exp Zool 1997 Jun 15;278(3):178-88 12 Citations |
| 1 | The low-affinity neurotrophin receptor p75 regulates the function but not the selective survival of specific subpopulations of sensory neurons. (Stucky CL, Koltzenburg M) J Neurosci 1997 Jun 01;17(11):4398-405 61 Citations |
| 1 | Differential rescue of the renal and hepatic disease in an autosomal recessive polycystic kidney disease mouse mutant. A new model to study the liver lesion. (Yoder BK, Richards WG, Sommardahl C, Sweeney WE, Michaud EJ, Wilkinson JE, Avner ED, Woychik RP) Am J Pathol 1997 Jun;150(6):2231-41 33 Citations |
| 1 | Myc and Ras collaborate in inducing accumulation of active cyclin E/Cdk2 and E2F. (Leone G, DeGregori J, Sears R, Jakoi L, Nevins JR) Nature 1997 May 22;387(6631):422-6 410 Citations |
| 1 | The role of CD4+ and CD8+ T cells in demyelinating disease following Theiler's virus infection: a model for multiple sclerosis. (Rodriguez M, Rivera-Quinones C, Murray PD, Kariuki Njenga M, Wettstein PJ, Mak T) J Neurovirol 1997 May;3 Suppl 1:S43-5 10 Citations |
| 1 | In vivo experimental studies on the role of free radicals in photodynamic therapy. III. Photodynamic effect on free radicals generated in cell cultures. (Gál D, Kriska T, Maltseva E) Biochem Biophys Res Commun 1997 Apr 07;233(1):173-6 15 Citations |
| 1 | Isolation and characterization of an attenuated strain of Pseudomonas aeruginosa AC869, a 3,5-dichlorobenzoate degrader. (Zhou X, George SE, Frank DW, Utley M, Gilmour I, Krogfelt KA, Claxton LD, Laux DC, Cohen PS) Appl Environ Microbiol 1997 Apr;63(4):1389-95 7 Citations |
| 1 | Complementation of reduced survival, hypotension, and renal abnormalities in angiotensinogen-deficient mice by the human renin and human angiotensinogen genes. (Davisson RL, Kim HS, Krege JH, Lager DJ, Smithies O, Sigmund CD) J Clin Invest 1997 Mar 15;99(6):1258-64 66 Citations |
| 1 | Cadmium induced alterations in extrathyroidal conversion of thyroxine to triiodothyronine by type-I iodothyronine 5'-monodeiodinase in male mouse. (Gupta P, Chaurasia SS, Maiti PK, Kar A) Horm Metab Res 1997 Mar;29(3):151-2 25 Citations |
| 1 | Selection of retrovirally transduced cells to enhance the efficiency of gene therapy. (Medin JA, Karlsson S) Proc Assoc Am Physicians 1997 Mar;109(2):111-9 11 Citations |
| 1 | Genetic mapping of a mouse ocular malformation locus, Tcm, to chromosome 4. (Zhou E, Grimes P, Favor J, Koeberlein B, Pretsch W, Neuhauser-Klaus A, Sidjanin D, Stambolian D) Mamm Genome 1997 Mar;8(3):178-81 19 Citations |
| 1 | Localization and expression of the c-kit receptor protein in human and rodent testis and sperm. (Sandlow JI, Feng HL, Sandra A) Urology 1997 Mar;49(3):494-500 53 Citations |
| 1 | In vitro mutagenicity of the plasmacytomagenic agent pristane (2,6,10,14-tetramethylpentadecane). (Felix K, Potter M, Bornkamm GW, Janz S) Cancer Lett 1997 Feb 26;113(1-2):71-6 4 Citations |
| 1 | Donor gamma delta T lymphocytes promote allogeneic engraftment across the major histocompatibility barrier in mice. (Drobyski WR, Majewski D) Blood 1997 Feb 01;89(3):1100-9 40 Citations |
| 1 | Effect of hypothermia on the merocyanine 540-mediated purging of hematopoietic cells. (Yamazaki T, Sieber F) J Hematother 1997 Feb;6(1):31-9 10 Citations |
| 1 | IFN-gamma-activated primary murine astrocytes express B7 costimulatory molecules and prime naive antigen-specific T cells. (Nikcevich KM, Gordon KB, Tan L, Hurst SD, Kroepfl JF, Gardinier M, Barrett TA, Miller SD) J Immunol 1997 Jan 15;158(2):614-21 141 Citations |
| 1 | Biosynthesis of renin in mouse kidney tumor As4.1 cells. (Jones CA, Petrovic N, Novak EK, Swank RT, Sigmund CD, Gross KW) Eur J Biochem 1997 Jan 15;243(1-2):181-90 27 Citations |
| 1 | The heterotrimeric G protein G alpha i2 mediates lysophosphatidic acid-stimulated induction of the c-fos gene in mouse fibroblasts. (Chuprun JK, Raymond JR, Blackshear PJ) J Biol Chem 1997 Jan 10;272(2):773-81 33 Citations |
| 1 | The alkyl-lysophospholipid, ET-18-OCH3 synergistically enhances the Merocyanine 540-mediated photoinactivation of leukemia cells: implications for the extracorporeal purging of autologous hematopoietic stem cells. (Yamazaki T, Sieber F) Bone Marrow Transplant 1997 Jan;19(2):113-9 22 Citations |
| 1 | Identification and molecular cloning of a 67-kilodalton protein in Schistosoma japonicum homologous to a family of actin-binding proteins. (Kurtis JD, Ramirez BL, Wiest PM, Dong KL, El-Meanawy A, Petzke MM, Johnson JH, Edmison J, Maier RA Jr, Olds GR) Infect Immun 1997 Jan;65(1):344-7 14 Citations |
| 1 | Migration of cells with immunoglobulin/c-myc recombinations in lymphoid tissues of mice. (Müller JR, Jones GM, Janz S, Potter M) Blood 1997 Jan 01;89(1):291-6 29 Citations |
| 1 | Lipid peroxidation in photodynamically stressed mammalian cells: use of cholesterol hydroperoxides as mechanistic reporters. (Geiger PG, Korytowski W, Lin F, Girotti AW) Free Radic Biol Med 1997;23(1):57-68 51 Citations |
| 1 | Temporospatial expression of the small HSP/alpha B-crystallin in cardiac and skeletal muscle during mouse development. (Benjamin IJ, Shelton J, Garry DJ, Richardson JA) Dev Dyn 1997 Jan;208(1):75-84 74 Citations |
| 1 | Generation of immunoglobulin/c-myc recombinations in murine Peyer's patch follicles. (Müller JR, Mushinski EB, Jones GM, Williams JA, Janz S, Hausner PF, Potter M) Curr Top Microbiol Immunol 1997;224:251-5 4 Citations |
| 1 | Genetic recombinations between c-myc and Igh mu as precursors for recombinations between c-myc and Igh alpha in BALB/c plasmacytomas. (Janz S, Kovalchuk AL, Müller JR, Potter M) Curr Top Microbiol Immunol 1997;224:241-50 2 Citations |
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| 1 | The accumulation of an E2F-p130 transcriptional repressor distinguishes a G0 cell state from a G1 cell state. (Smith EJ, Leone G, DeGregori J, Jakoi L, Nevins JR) Mol Cell Biol 1996 Dec;16(12):6965-76 209 Citations |
| 1 | Cloning and characterization of a novel bicoid-related homeobox transcription factor gene, RIEG, involved in Rieger syndrome. (Semina EV, Reiter R, Leysens NJ, Alward WL, Small KW, Datson NA, Siegel-Bartelt J, Bierke-Nelson D, Bitoun P, Zabel BU, Carey JC, Murray JC) Nat Genet 1996 Dec;14(4):392-9 801 Citations |
| 1 | Involvement of Rabphilin-3A in cortical granule exocytosis in mouse eggs. (Masumoto N, Sasaki T, Tahara M, Mammoto A, Ikebuchi Y, Tasaka K, Tokunaga M, Takai Y, Miyake A) J Cell Biol 1996 Dec;135(6 Pt 2):1741-7 44 Citations |
| 1 | The mouse mammary tumor virus env gene is the source of a CD8+ T-cell-stimulating peptide presented by a major histocompatibility complex class I molecule in a murine thymoma. (Malarkannan S, Serwold T, Nguyen V, Sherman LA, Shastri N) Proc Natl Acad Sci U S A 1996 Nov 26;93(24):13991-6 23 Citations |
| 1 | Identification of a novel RalGDS-related protein as a candidate effector for Ras and Rap1. (Peterson SN, Trabalzini L, Brtva TR, Fischer T, Altschuler DL, Martelli P, Lapetina EG, Der CJ, White GC 2nd) J Biol Chem 1996 Nov 22;271(47):29903-8 59 Citations |
| 1 | Nitric oxide: a prostaglandin H synthase 1 and 2 reducing cosubstrate that does not stimulate cyclooxygenase activity or prostaglandin H synthase expression in murine macrophages. (Curtis JF, Reddy NG, Mason RP, Kalyanaraman B, Eling TE) Arch Biochem Biophys 1996 Nov 15;335(2):369-76 64 Citations |
| 1 | Alloreactive CD8+ T cells can recognize unusual, rare, and unique processed peptide/MHC complexes. (Malarkannan S, Gonzalez F, Nguyen V, Adair G, Shastri N) J Immunol 1996 Nov 15;157(10):4464-73 36 Citations |
| 1 | Multicolour spectral karyotyping of mouse chromosomes. (Liyanage M, Coleman A, du Manoir S, Veldman T, McCormack S, Dickson RB, Barlow C, Wynshaw-Boris A, Janz S, Wienberg J, Ferguson-Smith MA, Schröck E, Ried T) Nat Genet 1996 Nov;14(3):312-5 256 Citations |
| 1 | Reactive oxygen species block sperm-egg fusion via oxidation of sperm sulfhydryl proteins in mice. (Mammoto A, Masumoto N, Tahara M, Ikebuchi Y, Ohmichi M, Tasaka K, Miyake A) Biol Reprod 1996 Nov;55(5):1063-8 55 Citations |
| 1 | PCR-based gene targeting of the inducible nitric oxide synthase (NOS2) locus in murine ES cells, a new and more cost-effective approach. (Randolph DA, Verbsky JW, Yang L, Fang Y, Hakem R, Fields LE) Transgenic Res 1996 Nov;5(6):413-20 6 Citations |
| 1 | Inappropriate splicing of a chimeric gene containing a large internal exon results in exon skipping in transgenic mice. (Davisson RL, Nuutinen N, Coleman ST, Sigmund CD) Nucleic Acids Res 1996 Oct 15;24(20):4023-8 10 Citations |
| 1 | Induction of apoptosis by anti-CD3 epsilon F(ab')2 in antigen receptor transgenic murine T cells activated by specific peptide. (Yu XZ, Zhu L, Davis JE, Tso JY, Hansen JA, Anasetti C) J Immunol 1996 Oct 15;157(8):3420-9 20 Citations |
| 1 | Modulation of in vitro and in vivo T-cell responses by transferrin-gallium and gallium nitrate. (Drobyski WR, Ul-Haq R, Majewski D, Chitambar CR) Blood 1996 Oct 15;88(8):3056-64 26 Citations |
| 1 | The MutT proteins or "Nudix" hydrolases, a family of versatile, widely distributed, "housecleaning" enzymes. (Bessman MJ, Frick DN, O'Handley SF) J Biol Chem 1996 Oct 11;271(41):25059-62 613 Citations |
| 1 | Complexes of non-cationic liposomes and histone H1 mediate efficient transfection of DNA without encapsulation. (Hagstrom JE, Sebestyen MG, Budker V, Ludtke JJ, Fritz JD, Wolff JA) Biochim Biophys Acta 1996 Oct 02;1284(1):47-55 73 Citations |
| 1 | Functional correction of renal defects in a mouse model for ARPKD through expression of the cloned wild-type Tg737 cDNA. (Yoder BK, Richards WG, Sommardahl C, Sweeney WE, Michaud EJ, Wilkinson JE, Avner ED, Woychik RP) Kidney Int 1996 Oct;50(4):1240-8 33 Citations |
| 1 | Evidence that two phenotypically distinct mouse PKD mutations, bpk and jcpk, are allelic. (Guay-Woodford LM, Bryda EC, Christine B, Lindsey JR, Collier WR, Avner ED, D'Eustachio P, Flaherty L) Kidney Int 1996 Oct;50(4):1158-65 34 Citations |
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| 1 | The graft-versus-leukemia effect of post-transplant donor leukocyte infusion. (Johnson BD, Hanke CA, Truitt RL) Leuk Lymphoma 1996 Sep;23(1-2):1-9 13 Citations |
| 1 | Cytotoxic T cell-resistant variants are selected in a virus-induced demyelinating disease. (Pewe L, Wu GF, Barnett EM, Castro RF, Perlman S) Immunity 1996 Sep;5(3):253-62 84 Citations |
| 1 | Regulation of human renin mRNA expression and protein release in transgenic mice. (Thompson MW, Smith SB, Sigmund CD) Hypertension 1996 Aug;28(2):290-6 25 Citations |
| 1 | Gene transfer into mammalian cells using histone-condensed plasmid DNA. (Fritz JD, Herweijer H, Zhang G, Wolff JA) Hum Gene Ther 1996 Aug 01;7(12):1395-404 169 Citations |
| 1 | Correction in trans for Fabry disease: expression, secretion and uptake of alpha-galactosidase A in patient-derived cells driven by a high-titer recombinant retroviral vector. (Medin JA, Tudor M, Simovitch R, Quirk JM, Jacobson S, Murray GJ, Brady RO) Proc Natl Acad Sci U S A 1996 Jul 23;93(15):7917-22 71 Citations |
| 1 | Delayed-type hypersensitivity in mast cell-deficient mice: dependence on platelets for expression of contact sensitivity. (Geba GP, Ptak W, Anderson GM, Paliwal V, Ratzlaff RE, Levin J, Askenase PW) J Immunol 1996 Jul 15;157(2):557-65 88 Citations |
| 1 | Expression of the serum response factor gene is regulated by serum response factor binding sites. (Spencer JA, Misra RP) J Biol Chem 1996 Jul 12;271(28):16535-43 76 Citations |
| 1 | Enzymatic reducibility in relation to cytotoxicity for various cholesterol hydroperoxides. (Korytowski W, Geiger PG, Girotti AW) Biochemistry 1996 Jul 02;35(26):8670-9 43 Citations |
| 1 | Role of hydrogen peroxide in the cytotoxic effects of UVA/B radiation on mammalian cells. (Bertling CJ, Lin F, Girotti AW) Photochem Photobiol 1996 Jul;64(1):137-42 45 Citations |
| 1 | Treatment of donor mice with an alpha beta T-cell receptor monoclonal antibody induces prolonged T-cell nonresponsiveness and effectively prevents lethal graft-versus-host disease in murine recipients of major histocompatibility complex (MHC)-matched and MHC-mismatched donor marrow grafts. (Drobyski WR, Majewski D) Blood 1996 Jun 15;87(12):5355-69 11 Citations |
| 1 | In vivo experimental studies on the role of free radicals in photodynamic therapy. II. Photodynamic effect on free radical concentration in mice tumors measured by ESR spectroscopy. (Kriska T, Mal'tseva E, Gál D) Biochem Biophys Res Commun 1996 Jun 05;223(1):136-40 12 Citations |
| 1 | Dynamics of cortical granule exocytosis at fertilization in living mouse eggs. (Tahara M, Tasaka K, Masumoto N, Mammoto A, Ikebuchi Y, Miyake A) Am J Physiol 1996 May;270(5 Pt 1):C1354-61 48 Citations |
| 1 | Nitric oxide production by the rat insulinoma cell line, RINm5F, Is specific for IL-1: a spectrophotometric IL-1 bioassay. (Hill JR, Corbett JA, Baldwin AC, McDaniel ML) Anal Biochem 1996 Apr 05;236(1):14-9 18 Citations |
| 1 | Endogenous altered peptide ligands can affect peripheral T cell responses. (Vidal K, Hsu BL, Williams CB, Allen PM) J Exp Med 1996 Apr 01;183(4):1311-21 60 Citations |
| 1 | Mycoplasma-like organisms in Hodgkin's disease. (Johnson L, Wirostko E, Wirostko W, Wirostko B) Lancet 1996 Mar 30;347(9005):901-2 7 Citations |
| 1 | Characterization of the sphingomyelin content of isolated pancreatic islets. Evaluation of the role of sphingomyelin hydrolysis in the action of interleukin-1 to induce islet overproduction of nitric oxide. (Kwon G, Bohrer A, Han X, Corbett JA, Ma Z, Gross RW, McDaniel ML, Turk J) Biochim Biophys Acta 1996 Mar 29;1300(1):63-72 23 Citations |
| 1 | Cardioprotective effects of 70-kDa heat shock protein in transgenic mice. (Radford NB, Fina M, Benjamin IJ, Moreadith RW, Graves KH, Zhao P, Gavva S, Wiethoff A, Sherry AD, Malloy CR, Williams RS) Proc Natl Acad Sci U S A 1996 Mar 19;93(6):2339-42 250 Citations |
| 1 | Effect of intracellular and extracellular ion changes on E-C coupling and skeletal muscle fatigue. (Fitts RH, Balog EM) Acta Physiol Scand 1996 Mar;156(3):169-81 49 Citations |
| 1 | A bicistronic therapeutic retroviral vector enables sorting of transduced CD34+ cells and corrects the enzyme deficiency in cells from Gaucher patients. (Medin JA, Migita M, Pawliuk R, Jacobson S, Amiri M, Kluepfel-Stahl S, Brady RO, Humphries RK, Karlsson S) Blood 1996 Mar 01;87(5):1754-62 39 Citations |
| 1 | Two distinct human parainfluenza virus type 1 genotypes detected during the 1991 Milwaukee epidemic. (Henrickson KJ, Savatski LL) J Clin Microbiol 1996 Mar;34(3):695-700 16 Citations |
| 1 | Identification of six novel autophosphorylation sites on fibroblast growth factor receptor 1 and elucidation of their importance in receptor activation and signal transduction. (Mohammadi M, Dikic I, Sorokin A, Burgess WH, Jaye M, Schlessinger J) Mol Cell Biol 1996 Mar;16(3):977-89 353 Citations |
| 1 | Regulated expression of CD36 during monocyte-to-macrophage differentiation: potential role of CD36 in foam cell formation. (Huh HY, Pearce SF, Yesner LM, Schindler JL, Silverstein RL) Blood 1996 Mar 01;87(5):2020-8 243 Citations |
| 1 | Human enteric defensins. Gene structure and developmental expression. (Mallow EB, Harris A, Salzman N, Russell JP, DeBerardinis RJ, Ruchelli E, Bevins CL) J Biol Chem 1996 Feb 23;271(8):4038-45 274 Citations |
| 1 | Chronic hypertension and altered baroreflex responses in transgenic mice containing the human renin and human angiotensinogen genes. (Merrill DC, Thompson MW, Carney CL, Granwehr BP, Schlager G, Robillard JE, Sigmund CD) J Clin Invest 1996 Feb 15;97(4):1047-55 160 Citations |
| 1 | CD36 participates in the phagocytosis of rod outer segments by retinal pigment epithelium. (Ryeom SW, Sparrow JR, Silverstein RL) J Cell Sci 1996 Feb;109 ( Pt 2):387-95 190 Citations |
| 1 | Pancreatic adenocarcinoma cell line, MDAPanc-28, with features of both acinar and ductal cells. (Frazier ML, Fernández E, de Llorens R, Brown NM, Pathak S, Cleary KR, Abbruzzese JL, Berry K, Olive M, Le Maistre A, Evans DB) Int J Pancreatol 1996 Feb;19(1):31-8 30 Citations |
| 1 | Dorsal laminectomy in the adult mouse: a model for nervous system research. (Ellegala DB, Tassone JC, Avellino AM, Pekow CA, Cunningham ML, Kliot M) Lab Anim Sci 1996 Feb;46(1):86-9 8 Citations |
| 1 | Detection of immunoglobulin/c-myc recombinations in mice that are resistant to plasmacytoma induction. (Müller JR, Jones GM, Potter M, Janz S) Cancer Res 1996 Jan 15;56(2):419-23 25 Citations |
| 1 | Induction of mitogen-activated protein kinase phosphatase 1 by the stress-activated protein kinase signaling pathway but not by extracellular signal-regulated kinase in fibroblasts. (Bokemeyer D, Sorokin A, Yan M, Ahn NG, Templeton DJ, Dunn MJ) J Biol Chem 1996 Jan 12;271(2):639-42 153 Citations |
| 1 | Regulation of inducible nitric oxide synthase expression by macrophage purinoreceptors and calcium. (Denlinger LC, Fisette PL, Garis KA, Kwon G, Vazquez-Torres A, Simon AD, Nguyen B, Proctor RA, Bertics PJ, Corbett JA) J Biol Chem 1996 Jan 05;271(1):337-42 159 Citations |
| 1 | DNA sequence analysis of the genetic recombination between Igh6 and Myc in an uncommon BALB/c plasmacytoma, TEPC 1194. (Kovalchuk AL, Potter M, Janz S) Immunogenetics 1996;44(2):151-6 6 Citations |
| 1 | Cytotoxicity and membrane damage in vitro by inclusion complexes between gamma-cyclodextrin and siloxanes. (Felix K, Janz S, Pitha J, Williams JA, Mushinski EB, Bornkamm GW, Potter M) Curr Top Microbiol Immunol 1996;210:93-9 9 Citations |
| 1 | A monoclonal natural autoantibody that promotes remyelination suppresses central nervous system inflammation and increases virus expression after Theiler's virus-induced demyelination. (Miller DJ, Njenga MK, Murray PD, Leibowitz J, Rodriguez M) Int Immunol 1996 Jan;8(1):131-41 29 Citations |
| 1 | Cell cycle control of T cell apoptosis induced by activation through the T cell antigen receptor. (Chalupny NJ, Zhu L, Yu XZ, Anasetti C) Adv Exp Med Biol 1996;406:57-67 |
| 1 | Silicone-induced T cell proliferation in mice. (McDonald AH, Weir K, Sanger JR) Curr Top Microbiol Immunol 1996;210:189-98 8 Citations |
| 1 | Further characterization of delta aroA delta virG Shigella flexneri 2a strain CVD 1203 as a mucosal Shigella vaccine and as a live-vector vaccine for delivering antigens of enterotoxigenic Escherichia coli. (Noriega FR, Losonsky G, Wang JY, Formal SB, Levine MM) Infect Immun 1996 Jan;64(1):23-7 71 Citations |
| 1 | Completion of the DNA sequence determination of the Igh2 locus of the mouse: the 5'-IA region. (Janz S, Roschke VV) Immunogenetics 1996;43(1-2):101-4 1 Citation |
| 1 | Selection of transduced CD34+ progenitors and enzymatic correction of cells from Gaucher patients, with bicistronic vectors. (Migita M, Medin JA, Pawliuk R, Jacobson S, Nagle JW, Anderson S, Amiri M, Humphries RK, Karlsson S) Proc Natl Acad Sci U S A 1995 Dec 19;92(26):12075-9 52 Citations |
| 1 | Inhibition of mouse placental lactogen-II release from placental cells by interleukin-1 after mid-pregnancy. (Yamaguchi M, Sakata M, Ogura K, Adachi K, Mammoto A, Miyake A) J Endocrinol 1995 Dec;147(3):423-9 3 Citations |
| 1 | Differential gene expression and regulation of renal angiotensin II receptor subtypes (AT1 and AT2) during fetal life in sheep. (Robillard JE, Page WV, Mathews MS, Schutte BC, Nuyt AM, Segar JL) Pediatr Res 1995 Dec;38(6):896-904 55 Citations |
| 1 | A rare cryptic translation product is presented by Kb major histocompatibility complex class I molecule to alloreactive T cells. (Malarkannan S, Afkarian M, Shastri N) J Exp Med 1995 Dec 01;182(6):1739-50 64 Citations |
| 1 | KBM-7, a human myeloid leukemia cell line with double Philadelphia chromosomes lacking normal c-ABL and BCR transcripts. (Andersson BS, Collins VP, Kurzrock R, Larkin DW, Childs C, Ost A, Cork A, Trujillo JM, Freireich EJ, Siciliano MJ) Leukemia 1995 Dec;9(12):2100-8 |
| 1 | Transgenic animals in the study of blood pressure regulation and hypertension. (Thompson MW, Merrill DC, Yang G, Robillard JE, Sigmund CD) Am J Physiol 1995 Nov;269(5 Pt 1):E793-803 18 Citations |
| 1 | Differences between Burkitt's lymphomas and mouse plasmacytomas in the immunoglobulin heavy chain/c-myc recombinations that occur in their chromosomal translocations. (Müller JR, Janz S, Potter M) Cancer Res 1995 Nov 01;55(21):5012-8 30 Citations |
| 1 | Soluble T cell receptors: detection and quantitative assay in fluid phase via ELISA or immuno-PCR. (Sperl J, Paliwal V, Ramabhadran R, Nowak B, Askenase PW) J Immunol Methods 1995 Oct 26;186(2):181-94 26 Citations |
| 1 | Activation of the EGF receptor by insertional mutations in its juxtamembrane regions. (Sorokin A) Oncogene 1995 Oct 19;11(8):1531-40 30 Citations |
| 1 | Potentiation of merocyanine 540-mediated photodynamic therapy by salicylate and related drugs. (Traul DL, Anderson GS, Bilitz JM, Krieg M, Sieber F) Photochem Photobiol 1995 Oct;62(4):790-9 7 Citations |
| 1 | Tumor-specific anti-epidermal growth factor receptor variant III monoclonal antibodies: use of the tyramine-cellobiose radioiodination method enhances cellular retention and uptake in tumor xenografts. (Reist CJ, Archer GE, Kurpad SN, Wikstrand CJ, Vaidyanathan G, Willingham MC, Moscatello DK, Wong AJ, Bigner DD, Zalutsky MR) Cancer Res 1995 Oct 01;55(19):4375-82 109 Citations |
| 1 | Loss of membrane integrity and inhibition of type-I iodothyronine 5'-monodeiodinase activity by fenvalerate in female mouse. (Maiti PK, Kar A, Gupta P, Chaurasia SS) Biochem Biophys Res Commun 1995 Sep 25;214(3):905-9 70 Citations |
| 1 | 1 alpha, 25-dihydroxyvitamin D3 receptor ontogenesis in fetal renal development. (Johnson JA, Grande JP, Roche PC, Sweeney WE Jr, Avner ED, Kumar R) Am J Physiol 1995 Sep;269(3 Pt 2):F419-28 29 Citations |
| 1 | Photodynamically generated 3-beta-hydroxy-5 alpha-cholest-6-ene-5- hydroperoxide: toxic reactivity in membranes and susceptibility to enzymatic detoxification. (Geiger PG, Korytowski W, Girotti AW) Photochem Photobiol 1995 Sep;62(3):580-7 36 Citations |
| 1 | Molecular cloning and structural characterization of the human histidase gene (HAL). (Suchi M, Sano H, Mizuno H, Wada Y) Genomics 1995 Sep 01;29(1):98-104 42 Citations |
| 1 | Stimulatory and inhibitory effects of iron on photodynamic inactivation of leukemia cells. (Lin F, Girotti AW) Photochem Photobiol 1995 Sep;62(3):528-34 7 Citations |
| 1 | High-performance liquid chromatography with mercury cathode electrochemical detection: application to lipid hydroperoxide analysis. (Korytowski W, Geiger PG, Girotti AW) J Chromatogr B Biomed Appl 1995 Aug 18;670(2):189-97 54 Citations |
| 2 | Inhibition of macrophage-dependent low density lipoprotein oxidation by nitric-oxide donors. (Hogg N, Struck A, Goss SP, Santanam N, Joseph J, Parthasarathy S, Kalyanaraman B) J Lipid Res 1995 Aug;36(8):1756-62 78 Citations |
| 1 | Transfer of the human glucocerebrosidase gene into hematopoietic stem cells of nonablated recipients: successful engraftment and long-term expression of the transgene. (Schiffmann R, Medin JA, Ward JM, Stahl S, Cottler-Fox M, Karlsson S) Blood 1995 Aug 01;86(3):1218-27 43 Citations |
| 1 | Monoclonal antibodies against EGFRvIII are tumor specific and react with breast and lung carcinomas and malignant gliomas. (Wikstrand CJ, Hale LP, Batra SK, Hill ML, Humphrey PA, Kurpad SN, McLendon RE, Moscatello D, Pegram CN, Reist CJ) Cancer Res 1995 Jul 15;55(14):3140-8 473 Citations |
| 1 | Tissue-specific expression of novel messenger ribonucleic acids cloned from a renin-expressing kidney tumor cell line (As4.1). (Thompson HA, Burson JM, Lang JA, Gross KW, Sigmund CD) Endocrinology 1995 Jul;136(7):3037-45 9 Citations |
| 1 | Regulation of mouse soluble interleukin-6 receptor secretion by decidua. (Yamaguchi M, Mammoto A, Taga T, Kishimoto T, Miyake A) Biochem Biophys Res Commun 1995 Jun 26;211(3):1077-82 6 Citations |
| 1 | Biliary epithelial cells from mice with congenital polycystic kidney disease are hyperresponsive to epidermal growth factor. (Nauta J, Sweeney WE, Rutledge JC, Avner ED) Pediatr Res 1995 Jun;37(6):755-63 41 Citations |
| 1 | Disposition of the plasmacytomagenic alkane pristane (2,6,10,14-tetramethylpentadecane) in mice. (Janz S, Shacter E) Cancer Biochem Biophys 1995 Jun;15(1):25-34 7 Citations |
| 1 | Delayed infusion of immunocompetent donor cells after bone marrow transplantation breaks graft-host tolerance allows for persistent antileukemic reactivity without severe graft-versus-host disease. (Johnson BD, Truitt RL) Blood 1995 Jun 01;85(11):3302-12 135 Citations |
| 1 | Expression of deletion-containing dystrophins in mdx muscle: implications for gene therapy and dystrophin function. (Fritz JD, Danko I, Roberds SL, Campbell KP, Latendresse JS, Wolff JA) Pediatr Res 1995 Jun;37(6):693-700 10 Citations |
| 1 | Selenoperoxidase-dependent glutathione cycle activity in peroxide-challenged leukemia cells. (Korytowski W, Bachowski GJ, Geiger PG, Lin F, Zhao G, Girotti AW) Biochim Biophys Acta 1995 May 29;1267(1):31-40 9 Citations |
| 1 | Use of anti-CD3 epsilon F(ab')2 fragments in vivo to modulate graft-versus-host disease without loss of graft-versus-leukemia reactivity after MHC-matched bone marrow transplantation. (Johnson BD, McCabe C, Hanke CA, Truitt RL) J Immunol 1995 May 15;154(10):5542-54 41 Citations |
| 1 | Adoptive cell transfer of contact sensitivity-initiation mediated by nonimmune cells sensitized with monoclonal IgE antibodies. Dependence on host skin mast cells. (Matsuda H, Ushio H, Paliwal V, Ptak W, Askenase PW) J Immunol 1995 May 15;154(10):5080-92 18 Citations |
| 1 | Regulation of allergic contact sensitivity in mice: soluble alpha beta T cell receptors, derived via cDNA transfection and enzymatic cleavage from the surface of T cells, protect contact sensitivity effector T cells from active T cell suppression. (Paliwal V, Ptak W, Askenase PW) Int Arch Allergy Immunol 1995;107(1-3):365 1 Citation |
| 1 | Effect of serum proteins on sodium-linked transport processes in cultured kidney cells. (Blumenthal SS, Lewand DL, Tipnis PA, Kleinman JG) J Am Soc Nephrol 1995 May;5(11):1964-70 3 Citations |
| 1 | Gamma delta T cells in normal spleen assist immunized alpha beta T cells in the adoptive cell transfer of contact sensitivity. Effect of Bordetella pertussis, cyclophosphamide, and antibodies to determinants on suppressor cells. (Askenase PW, Szczepanik M, Ptak M, Paliwal V, Ptak W) J Immunol 1995 Apr 15;154(8):3644-53 40 Citations |
| 1 | Developmental regulation of alpha-fetoprotein expression in intestinal epithelial cells of transgenic mice. (Cirillo LA, Emerson JA, Vacher J, Tyner AL) Dev Biol 1995 Apr;168(2):395-405 5 Citations |
| 1 | Endogenous human renin expression and promoter activity in CALU-6, a pulmonary carcinoma cell line. (Lang JA, Yang G, Kern JA, Sigmund CD) Hypertension 1995 Apr;25(4 Pt 2):704-10 40 Citations |
| 1 | Anterograde tracing of trigeminal afferent pathways from the murine tooth pulp to cortex using herpes simplex virus type 1. (Barnett EM, Evans GD, Sun N, Perlman S, Cassell MD) J Neurosci 1995 Apr;15(4):2972-84 92 Citations |
| 1 | CD36 induction on human monocytes upon adhesion to tumor necrosis factor-activated endothelial cells. (Huh HY, Lo SK, Yesner LM, Silverstein RL) J Biol Chem 1995 Mar 17;270(11):6267-71 54 Citations |
| 1 | Tyrosine kinase activity of the EGF receptor in murine metanephric organ culture. (Pugh JL, Sweeney WE Jr, Avner ED) Kidney Int 1995 Mar;47(3):774-81 54 Citations |
| 2 | Amplification and hyperexpression of the catalase gene in selenoperoxidase-deficient leukemia cells. (Lin F, Jackson VE, Girotti AW) Arch Biochem Biophys 1995 Feb 20;317(1):7-18 13 Citations |
| 1 | Epidermal growth factor receptor expression is abnormal in murine polycystic kidney. (Orellana SA, Sweeney WE, Neff CD, Avner ED) Kidney Int 1995 Feb;47(2):490-9 130 Citations |
| 1 | Translocation and activation of protein kinase C by the plasma cell tumor-promoting alkane pristane. (Janz S, Gawrisch K, Lester DS) Cancer Res 1995 Feb 01;55(3):518-24 12 Citations |
| 1 | Oxidized LDL binds to CD36 on human monocyte-derived macrophages and transfected cell lines. Evidence implicating the lipid moiety of the lipoprotein as the binding site. (Nicholson AC, Frieda S, Pearce A, Silverstein RL) Arterioscler Thromb Vasc Biol 1995 Feb;15(2):269-75 237 Citations |
| 1 | The role of MHC class I molecules in the generation of endogenous peptide/MHC complexes. (Malarkannan S, Goth S, Buchholz DR, Shastri N) J Immunol 1995 Jan 15;154(2):585-98 38 Citations |
| 1 | Genomic instability in B-cells and diversity of recombinations that activate c-myc. (Janz S, Jones GM, Müller JR, Potter M) Curr Top Microbiol Immunol 1995;194:373-80 5 Citations |
| 1 | Illegitimate recombinations between c-myc and immunoglobulin loci are remodeled by deletions in mouse plasmacytomas but not in Burkitt's lymphomas. (Müller JR, Janz S, Potter M) Curr Top Microbiol Immunol 1995;194:425-9 1 Citation |
| 1 | Spread of MHV-JHM from nasal cavity to white matter of spinal cord. Transneuronal movement and involvement of astrocytes. (Perlman S, Sun N, Barnett EM) Adv Exp Med Biol 1995;380:73-8 18 Citations |
| 1 | Localization of the murine homolog of the anaplastic lymphoma kinase (AlK) gene on mouse chromosome 17. (Mathew P, Morris SW, Kane JR, Shurtleff SA, Pasquini M, Jenkins NA, Gilbert DJ, Copeland NG) Cytogenet Cell Genet 1995;70(1-2):143-4 11 Citations |
| 1 | Functional expression of the human angiotensinogen gene in transgenic mice. (Yang G, Merrill DC, Thompson MW, Robillard JE, Sigmund CD) J Biol Chem 1994 Dec 23;269(51):32497-502 114 Citations |
| 1 | Chromosome 8 alterations accompany tumorigenesis in renin-SV40 T antigen transgenic mice. (Held WA, O'Brien JG, Kerns K, Gallagher JF, Sigmund CD, Gross KW) Cancer Res 1994 Dec 15;54(24):6496-9 5 Citations |
| 1 | Differences in the molecular structure of c-myc-activating recombinations in murine plasmacytomas and precursor cells. (Müller JR, Potter M, Janz S) Proc Natl Acad Sci U S A 1994 Dec 06;91(25):12066-70 35 Citations |
| 1 | The dihydropyridine nitrendipine inhibits [3H]MK 801 binding to mouse brain sections. (Filloux FM, Fitts RC, Skeen GA, White HS) Eur J Pharmacol 1994 Nov 15;269(3):325-30 15 Citations |
| 1 | Clostridium difficile toxin A therapy for HCT 116 human colon cancer in nude mice. (Redlich PN, Kushnaryov VM, Hernandez I, Grossberg SE) J Surg Oncol 1994 Nov;57(3):191-5 3 Citations |
| 1 | Inhibition of nitric oxide production is associated with enhanced weight loss, decreased survival, and impaired alloengraftment in mice undergoing graft-versus-host disease after bone marrow transplantation. (Drobyski WR, Keever CA, Hanson GA, McAuliffe T, Griffith OW) Blood 1994 Oct 01;84(7):2363-73 41 Citations |
| 1 | Influenza virus-specific CD4+ T helper type 2 T lymphocytes do not promote recovery from experimental virus infection. (Graham MB, Braciale VL, Braciale TJ) J Exp Med 1994 Oct 01;180(4):1273-82 256 Citations |
| 1 | Aluminum-induced DNA synthesis in osteoblasts: mediation by a G-protein coupled cation sensing mechanism. (Quarles LD, Hartle JE 2nd, Middleton JP, Zhang J, Arthur JM, Raymond JR) J Cell Biochem 1994 Sep;56(1):106-17 92 Citations |
| 1 | Differential expression of angiotensin receptor 1A and 1B in mouse. (Burson JM, Aguilera G, Gross KW, Sigmund CD) Am J Physiol 1994 Aug;267(2 Pt 1):E260-7 224 Citations |
| 1 | Characterization and use of crude alpha-subunit preparations for quantitative immunoblotting of G proteins. (Gettys TW, Sheriff-Carter K, Moomaw J, Taylor IL, Raymond JR) Anal Biochem 1994 Jul;220(1):82-91 45 Citations |
| 1 | Characterization of lipid hydroperoxides generated by photodynamic treatment of leukemia cells. (Bachowski GJ, Korytowski W, Girotti AW) Lipids 1994 Jul;29(7):449-59 36 Citations |
| 1 | Gallium nitrate delays the progression of microscopic disease in a human medulloblastoma murine model. (Whelan HT, Williams MB, Bajic DM, Flores RE, Schmidt MH, McAuliffe TL, Chitambar CR) Pediatr Neurol 1994 Jul;11(1):44-6 6 Citations |
| 2 | Enhancement of merocyanine 540 uptake and photodynamic cell killing by salicylates. (Feix JB, Anderson MS, Kalyanaraman B) Cancer Res 1994 Jul 01;54(13):3474-8 4 Citations |
| 1 | Internalization of fibroblast growth factor receptor is inhibited by a point mutation at tyrosine 766. (Sorokin A, Mohammadi M, Huang J, Schlessinger J) J Biol Chem 1994 Jun 24;269(25):17056-61 110 Citations |
| 1 | Binding of reovirus to receptor leads to conformational changes in viral capsid proteins that are reversible upon virus detachment. (Fernandes J, Tang D, Leone G, Lee PW) J Biol Chem 1994 Jun 24;269(25):17043-7 25 Citations |
| 1 | Candidate gene associated with a mutation causing recessive polycystic kidney disease in mice. (Moyer JH, Lee-Tischler MJ, Kwon HY, Schrick JJ, Avner ED, Sweeney WE, Godfrey VL, Cacheiro NL, Wilkinson JE, Woychik RP) Science 1994 May 27;264(5163):1329-33 322 Citations |
| 1 | Alpha 2A adrenergic receptors inhibit cAMP accumulation in embryonic stem cells which lack Gi alpha 2. (Raymond JR, Arthur JM, Casañas SJ, Olsen CL, Gettys TW, Mortensen RM) J Biol Chem 1994 May 06;269(18):13073-5 16 Citations |
| 2 | Prevention of gallium toxicity by hyperhydration in treatment of medulloblastoma. (Whelan HT, Williams MB, Bajic DM, Segura AD, McAuliffe TL, Chitambar CR) Pediatr Neurol 1994 May;10(3):217-20 6 Citations |
| 1 | Three-dimensional structure of a human class II histocompatibility molecule complexed with superantigen. (Jardetzky TS, Brown JH, Gorga JC, Stern LJ, Urban RG, Chi YI, Stauffacher C, Strominger JL, Wiley DC) Nature 1994 Apr 21;368(6473):711-8 526 Citations |
| 1 | Stabilization of an active dimeric form of the epidermal growth factor receptor by introduction of an inter-receptor disulfide bond. (Sorokin A, Lemmon MA, Ullrich A, Schlessinger J) J Biol Chem 1994 Apr 01;269(13):9752-9 107 Citations |
| 1 | Herpes simplex encephalitis in the temporal cortex and limbic system after trigeminal nerve inoculation. (Barnett EM, Jacobsen G, Evans G, Cassell M, Perlman S) J Infect Dis 1994 Apr;169(4):782-6 70 Citations |
| 1 | Monoclonal, antigen-specific, T cell contrasuppressor factor expresses determinants of TCR alpha-chain (not necessarily TCR beta-chain), having a molecular mass of about 40 kDa. (Paliwal V, Friedman AM, Ptak W, Askenase PW) J Immunol 1994 Mar 15;152(6):2811-20 19 Citations |
| 1 | Pharmacological enhancement of in vivo foreign gene expression in muscle. (Danko I, Fritz JD, Jiao S, Hogan K, Latendresse JS, Wolff JA) Gene Ther 1994 Mar;1(2):114-21 143 Citations |
| 1 | Cytoprotection against merocyanine 540-sensitized photoinactivation of the Na+,K(+)-adenosine triphosphatase in leukemia cells: glutathione and selenoperoxidase involvement. (Lin F, Girotti AW) Photochem Photobiol 1994 Mar;59(3):320-7 5 Citations |
| 1 | Transgenic animals as tools in hypertension research. (Lang JA, Sinclair NL, Burson JM, Sigmund CD) Proc Soc Exp Biol Med 1994 Feb;205(2):106-18 4 Citations |
| 1 | Interaction of the bHLH-zip domain of c-Myc with H1-type peptides. Characterization of helicity in the H1 peptides by NMR. (Draeger LJ, Mullen GP) J Biol Chem 1994 Jan 21;269(3):1785-93 46 Citations |
| 1 | Start site selection at the TATA-less carbamoyl-phosphate synthase (glutamine-hydrolyzing)/aspartate carbamoyltransferase/dihydroorotase promoter. (Kollmar R, Sukow KA, Sponagle SK, Farnham PJ) J Biol Chem 1994 Jan 21;269(3):2252-7 74 Citations |
| 1 | [The isolation and genetic characteristics of the new cell line of mouse myeloma spEBR-5 selected for ethidium bromide resistance and characterized by multiple drug resistance]. (Berezkina EV, Lipskaia LA, Grinchuk TM, Kovaleva ZV, Sorokina EA, Vasiukhin VI, Ignatova TN) Tsitologiia 1994;36(7):687-95 1 Citation |
| 1 | Selective incorporation of 111In-labeled PHOTOFRIN by glioma tissue in vivo. (Whelan HT, Kras LH, Ozker K, Bajic D, Schmidt MH, Liu Y, Trembath LA, Uzum F, Meyer GA, Segura AD) J Neurooncol 1994;22(1):7-13 21 Citations |
| 1 | Interferon-gamma and interleukin-1 beta induce nitric oxide formation from primary mouse astrocytes. (Hewett SJ, Corbett JA, McDaniel ML, Choi DW) Neurosci Lett 1993 Dec 24;164(1-2):229-32 108 Citations |
| 1 | Dystrophin expression improves myofiber survival in mdx muscle following intramuscular plasmid DNA injection. (Danko I, Fritz JD, Latendresse JS, Herweijer H, Schultz E, Wolff JA) Hum Mol Genet 1993 Dec;2(12):2055-61 70 Citations |
| 1 | Two neurotropic viruses, herpes simplex virus type 1 and mouse hepatitis virus, spread along different neural pathways from the main olfactory bulb. (Barnett EM, Cassell MD, Perlman S) Neuroscience 1993 Dec;57(4):1007-25 117 Citations |
| 2 | Inhibition of low-density lipoprotein oxidation by nitric oxide. Potential role in atherogenesis. (Hogg N, Kalyanaraman B, Joseph J, Struck A, Parthasarathy S) FEBS Lett 1993 Nov 15;334(2):170-4 376 Citations |
| 1 | Response to influenza infection in mice with a targeted disruption in the interferon gamma gene. (Graham MB, Dalton DK, Giltinan D, Braciale VL, Stewart TA, Braciale TJ) J Exp Med 1993 Nov 01;178(5):1725-32 226 Citations |
| 1 | Inhibition of nitric oxide formation does not protect murine cortical cell cultures from N-methyl-D-aspartate neurotoxicity. (Hewett SJ, Corbett JA, McDaniel ML, Choi DW) Brain Res 1993 Oct 22;625(2):337-41 71 Citations |
| 1 | Subcellular localization of Bcr, Abl, and Bcr-Abl proteins in normal and leukemic cells and correlation of expression with myeloid differentiation. (Wetzler M, Talpaz M, Van Etten RA, Hirsh-Ginsberg C, Beran M, Kurzrock R) J Clin Invest 1993 Oct;92(4):1925-39 180 Citations |
| 1 | Rotaviruses preferentially bind O-linked sialylglycoconjugates and sialomucins. (Willoughby RE) Glycobiology 1993 Oct;3(5):437-45 45 Citations |
| 1 | Major approaches for generating and analyzing transgenic mice. An overview. (Sigmund CD) Hypertension 1993 Oct;22(4):599-607 46 Citations |
| 1 | Nitric oxide production in islets from nonobese diabetic mice: aminoguanidine-sensitive and -resistant stages in the immunological diabetic process. (Corbett JA, Mikhael A, Shimizu J, Frederick K, Misko TP, McDaniel ML, Kanagawa O, Unanue ER) Proc Natl Acad Sci U S A 1993 Oct 01;90(19):8992-5 155 Citations |
| 1 | A growth factor-induced kinase phosphorylates the serum response factor at a site that regulates its DNA-binding activity. (Rivera VM, Miranti CK, Misra RP, Ginty DD, Chen RH, Blenis J, Greenberg ME) Mol Cell Biol 1993 Oct;13(10):6260-73 244 Citations |
| 1 | Retinoic acid induction of major histocompatibility complex class I genes in NTera-2 embryonal carcinoma cells involves induction of NF-kappa B (p50-p65) and retinoic acid receptor beta-retinoid X receptor beta heterodimers. (Segars JH, Nagata T, Bours V, Medin JA, Franzoso G, Blanco JC, Drew PD, Becker KG, An J, Tang T) Mol Cell Biol 1993 Oct;13(10):6157-69 69 Citations |
| 1 | Expression of the human renin gene in transgenic mice throughout ontogeny. (Sigmund CD) Pediatr Nephrol 1993 Oct;7(5):639-45 16 Citations |
| 2 | Hyperexpression of catalase in selenium-deprived murine L1210 cells. (Lin F, Thomas JP, Girotti AW) Arch Biochem Biophys 1993 Aug 15;305(1):176-85 20 Citations |
| 1 | Analysis of cholesterol and phospholipid hydroperoxides by high-performance liquid chromatography with mercury drop electrochemical detection. (Korytowski W, Bachowski GJ, Girotti AW) Anal Biochem 1993 Aug 15;213(1):111-9 58 Citations |
| 1 | Biological properties and growth in SCID mice of a new myelogenous leukemia cell line (KBM-5) derived from chronic myelogenous leukemia cells in the blastic phase. (Beran M, Pisa P, O'Brien S, Kurzrock R, Siciliano M, Cork A, Andersson BS, Kohli V, Kantarjian H) Cancer Res 1993 Aug 01;53(15):3603-10 61 Citations |
| 1 | Detection of recombinations between c-myc and immunoglobulin switch alpha in murine plasma cell tumors and preneoplastic lesions by polymerase chain reaction. (Janz S, Müller J, Shaughnessy J, Potter M) Proc Natl Acad Sci U S A 1993 Aug 01;90(15):7361-5 60 Citations |
| 1 | Human heat shock protein 70 (hsp70) protects murine cells from injury during metabolic stress. (Williams RS, Thomas JA, Fina M, German Z, Benjamin IJ) J Clin Invest 1993 Jul;92(1):503-8 154 Citations |
| 1 | Characterization of a partial cDNA clone encoding porcine skeletal muscle titin: comparison with rabbit and mouse skeletal muscle titin sequences. (Fritz JD, Wolff JA, Greaser ML) Comp Biochem Physiol B 1993 Jun;105(2):357-60 11 Citations |
| 1 | Mycoplasma-like organism induced murine cardiac microvasculopathy. A transmission electron microscopic study. (Johnson L, Wirostko E, Wirostko W, Rotterdam H) Pathol Res Pract 1993 May;189(4):448-52 5 Citations |
| 1 | The olfactory nerve and not the trigeminal nerve is the major site of CNS entry for mouse hepatitis virus, strain JHM. (Barnett EM, Perlman S) Virology 1993 May;194(1):185-91 85 Citations |
| 1 | The sensitivity of single-strand conformation polymorphism analysis for the detection of single base substitutions. (Sheffield VC, Beck JS, Kwitek AE, Sandstrom DW, Stone EM) Genomics 1993 May;16(2):325-32 594 Citations |
| 3 | Hyperbaric oxygen therapy and squamous cell carcinoma cell line growth. (Sklizovic D, Sanger JR, Kindwall EP, Fink JG, Grunert BK, Campbell BH) Head Neck 1993;15(3):236-40 17 Citations |
| 1 | Sp-1 binds promoter elements regulated by the RB protein and Sp-1-mediated transcription is stimulated by RB coexpression. (Udvadia AJ, Rogers KT, Higgins PD, Murata Y, Martin KH, Humphrey PA, Horowitz JM) Proc Natl Acad Sci U S A 1993 Apr 15;90(8):3265-9 198 Citations |
| 2 | Delayed infusion of normal donor cells after MHC-matched bone marrow transplantation provides an antileukemia reaction without graft-versus-host disease. (Johnson BD, Drobyski WR, Truitt RL) Bone Marrow Transplant 1993 Apr;11(4):329-36 134 Citations |
| 1 | Renal and biliary abnormalities in a new murine model of autosomal recessive polycystic kidney disease. (Nauta J, Ozawa Y, Sweeney WE Jr, Rutledge JC, Avner ED) Pediatr Nephrol 1993 Apr;7(2):163-72 103 Citations |
| 1 | A new murine model of autosomal recessive polycystic kidney disease. (Ozawa Y, Nauta J, Sweeney WE, Avner ED) Nihon Jinzo Gakkai Shi 1993 Apr;35(4):349-54 4 Citations |
| 1 | Selenoperoxidase-mediated cytoprotection against the damaging effects of tert-butyl hydroperoxide on leukemia cells. (Geiger PG, Lin F, Girotti AW) Free Radic Biol Med 1993 Mar;14(3):251-66 52 Citations |
| 1 | Release of nitric oxide during the T cell-independent pathway of macrophage activation. Its role in resistance to Listeria monocytogenes. (Beckerman KP, Rogers HW, Corbett JA, Schreiber RD, McDaniel ML, Unanue ER) J Immunol 1993 Feb 01;150(3):888-95 249 Citations |
| 1 | Photodynamic action of merocyanine 540 on leukemia cells: iron-stimulated lipid peroxidation and cell killing. (Lin F, Girotti AW) Arch Biochem Biophys 1993 Feb 01;300(2):714-23 46 Citations |
| 1 | Two distinct porcine natural killer lytic trigger molecules as PNK-E/G7 molecular complex. (Wierda WG, Johnson BD, Dato ME, Kim YB) Cell Immunol 1993 Feb;146(2):270-83 13 Citations |
| 1 | Detection of residual leukemia by the polymerase chain reaction and sequence-specific oligonucleotide probe hybridization after allogeneic bone marrow transplantation for AKR leukemia: a murine model for minimal residual disease. (Drobyski WR, Baxter-Lowe LA, Truitt RL) Blood 1993 Jan 15;81(2):551-9 11 Citations |
| 1 | Mouse hepatitis virus and herpes simplex virus move along different CNS pathways. (Perlman S, Barnett E, Jacobsen G) Adv Exp Med Biol 1993;342:313-8 8 Citations |
| 1 | Activated murine neutrophils induce unscheduled DNA synthesis in B lymphocytes. (Janz S, Shacter E) Mutat Res 1993 Jan;293(2):173-86 13 Citations |
| 2 | Purification and characterization of exoenzyme S from Pseudomonas aeruginosa 388. (Kulich SM, Frank DW, Barbieri JT) Infect Immun 1993 Jan;61(1):307-13 44 Citations |
| 1 | Transport of spin-labeled tetracycline across model and biological membranes. (Pezeshk A, Pezeshk V, Firlej A, Wojas J, Subczynski WK) Life Sci 1993;52(12):1071-8 8 Citations |
| 1 | Expression of four myosin heavy chain isoforms with development in mouse uterus. (Eddinger TJ, Wolf JA) Cell Motil Cytoskeleton 1993;25(4):358-68 33 Citations |
| 1 | Phototherapy, photochemotherapy, and bone marrow transplantation. (Sieber F) J Hematother 1993;2(1):43-62 22 Citations |
| 1 | Epithelial polarity and differentiation in polycystic kidney disease. (Avner ED) J Cell Sci Suppl 1993;17:217-22 36 Citations |
| 1 | The fluidity of DOPC bilayers and membrane fractions prepared from murine plasmacytoma cells is unchanged after incorporation of pristane (2,6,10,14-tetramethylpentadecane) as assessed by fluorescence polarization analysis. (Janz S, Krumbiegel M, Gawrisch K) Cancer Biochem Biophys 1992 Nov;13(2):85-92 4 Citations |
| 1 | Merocyanine 540-sensitized photoinactivation of leukemia cells: effects of dose fractionation. (Qiu K, Sieber F) Photochem Photobiol 1992 Oct;56(4):489-93 12 Citations |
| 1 | Cell surface ligands for rotavirus: mouse intestinal glycolipids and synthetic carbohydrate analogs. (Srnka CA, Tiemeyer M, Gilbert JH, Moreland M, Schweingruber H, de Lappe BW, James PG, Gant T, Willoughby RE, Yolken RH) Virology 1992 Oct;190(2):794-805 35 Citations |
| 1 | Selenoperoxidase-mediated cytoprotection against merocyanine 540-sensitized photoperoxidation and photokilling of leukemia cells. (Lin F, Geiger PG, Girotti AW) Cancer Res 1992 Oct 01;52(19):5282-90 52 Citations |
| 1 | The zonal expression of alpha-fetoprotein transgenes in the livers of adult mice. (Emerson JA, Vacher J, Cirillo LA, Tilghman SM, Tyner AL) Dev Dyn 1992 Sep;195(1):55-66 26 Citations |
| 1 | Antineoplastic effects of gallium nitrate on human medulloblastoma in vivo. (Whelan HT, Schmidt MH, Anderson GS, Chan BK, Hunter K, Kubacki D, Segura AD, Chitambar CR) Pediatr Neurol 1992;8(5):323-7 8 Citations |
| 1 | The calcium oxalate crystal growth inhibitor protein produced by mouse kidney cortical cells in culture is osteopontin. (Worcester EM, Blumenthal SS, Beshensky AM, Lewand DL) J Bone Miner Res 1992 Sep;7(9):1029-36 127 Citations |
| 1 | Abnormal sodium pump distribution during renal tubulogenesis in congenital murine polycystic kidney disease. (Avner ED, Sweeney WE Jr, Nelson WJ) Proc Natl Acad Sci U S A 1992 Aug 15;89(16):7447-51 97 Citations |
| 1 | What determines who develops graft-versus-host disease: the graft or the host (or both)? (Gale RP, Horowitz MM, Butturini A, Barrett AJ, Kolb HJ) Bone Marrow Transplant 1992 Aug;10(2):99-102 7 Citations |
| 1 | Immunodetection of biotinylated lymphocyte-surface proteins by enhanced chemiluminescence: a nonradioactive method for cell-surface protein analysis. (Meier T, Arni S, Malarkannan S, Poincelet M, Hoessli D) Anal Biochem 1992 Jul;204(1):220-6 100 Citations |
| 1 | A decrease in graft-vs.-host disease without loss of graft-vs.-leukemia reactivity after MHC-matched bone marrow transplantation by selective depletion of donor NK cells in vivo. (Johnson BD, Truitt RL) Transplantation 1992 Jul;54(1):104-12 52 Citations |
| 1 | Regulated tissue- and cell-specific expression of the human renin gene in transgenic mice. (Sigmund CD, Jones CA, Kane CM, Wu C, Lang JA, Gross KW) Circ Res 1992 May;70(5):1070-9 101 Citations |
| 1 | Lack of functional significance of Cys227 and Cys234 in terminal deoxynucleotidyltransferase. (Medin JA, Coleman MS) J Biol Chem 1992 Mar 15;267(8):5199-201 3 Citations |
| 1 | Nonsense codons in human beta-globin mRNA result in the production of mRNA degradation products. (Lim SK, Sigmund CD, Gross KW, Maquat LE) Mol Cell Biol 1992 Mar;12(3):1149-61 117 Citations |
| 3 | Interactions of merocyanine 540 with human brain tumor cells. (Whelan HT, Traul DL, Przybylski C, Segura A, Thomas J, Meyer G, Sieber F) Pediatr Neurol 1992;8(2):117-20 6 Citations |
| 1 | Cardiorespiratory effects of the novel opioid analgesic HP 736 in the anesthetized dog and conscious goat. (Hubbard JW, Locke KW, Forster HV, Brice AG, Pan LG, Lowry TF, Forster AM, Forster MA, Cornfeldt M, Vanselous CL) J Pharmacol Exp Ther 1992 Mar;260(3):1268-77 5 Citations |
| 1 | Pathophysiology of renal tubular cyst formation in murine models of polycystic kidney disease. (Sweeney WE Jr, Avner ED) Contrib Nephrol 1992;97:23-34 4 Citations |
| 1 | Merocyanine-sensitized photoinactivation of enveloped viruses. (Sieber F, O'Brien JM, Gaffney DK) Blood Cells 1992;18(1):117-27; discussion 128 41 Citations |
| 1 | Pseudomonas aeruginosa exoenzyme S. (Coburn J) Curr Top Microbiol Immunol 1992;175:133-43 39 Citations |
| 3 | Action spectra of the antileukemic and antiviral activities of merocyanine 540. (O'Brien JM, Singh RJ, Feix JB, Kalyanaraman B, Sieber F) Photochem Photobiol 1991 Nov;54(5):851-4 21 Citations |
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| 1 | Structure, expression, and regulation of the murine renin genes. (Sigmund CD, Gross KW) Hypertension 1991 Oct;18(4):446-57 117 Citations |
| 1 | Trimerization of the reovirus cell attachment protein (sigma 1) induces conformational changes in sigma 1 necessary for its cell-binding function. (Leone G, Duncan R, Lee PW) Virology 1991 Oct;184(2):758-61 19 Citations |
| 1 | The serum response factor is extensively modified by phosphorylation following its synthesis in serum-stimulated fibroblasts. (Misra RP, Rivera VM, Wang JM, Fan PD, Greenberg ME) Mol Cell Biol 1991 Sep;11(9):4545-54 87 Citations |
| 2 | Lethal damage to murine L1210 cells by exogenous lipid hydroperoxides: protective role of glutathione-dependent selenoperoxidases. (Geiger PG, Thomas JP, Girotti AW) Arch Biochem Biophys 1991 Aug 01;288(2):671-80 49 Citations |
| 1 | Mesangial cell immune injury. Synthesis, origin, and role of eicosanoids. (Lianos EA, Bresnahan BA, Pan C) J Clin Invest 1991 Aug;88(2):623-31 51 Citations |
| 1 | Renin promoter SV40 T-antigen transgenic mouse. A model of primary renal vascular hyperplasia. (Jacob HJ, Sigmund CD, Shockley TR, Gross KW, Dzau VJ) Hypertension 1991 Jun;17(6 Pt 2):1167-62 16 Citations |
| 1 | Evaluation of merocyanine 540-sensitized photoirradiation as a method for purging malarially infected red cells from blood. (Smith OM, Traul DL, McOlash L, Sieber F) J Infect Dis 1991 Jun;163(6):1312-7 16 Citations |
| 1 | Antibodies that neutralize human beta interferon biologic activity recognize a linear epitope: analysis by synthetic peptide mapping. (Redlich PN, Hoeprich PD Jr, Colby CB, Grossberg SE) Proc Natl Acad Sci U S A 1991 May 01;88(9):4040-4 40 Citations |
| 1 | Further characterization of PNK-E: a monoclonal antibody enhancing porcine natural killer cell activity. (Johnson BD, Wierda WG, Kim YB) Cell Immunol 1991 May;134(2):378-89 11 Citations |
| 1 | The spin trap, alpha-phenyl N-tert-butylnitrone, inhibits the oxidative modification of low density lipoprotein. (Kalyanaraman B, Joseph J, Parthasarathy S) FEBS Lett 1991 Mar 11;280(1):17-20 44 Citations |
| 1 | Different inhibitory actions of cyclosporine A and cyclosporine A-acetate on lipopolysaccharide-, interleukin 1-, 1,25 dihydroxyvitamin D3- and parathyroid hormone-stimulated calcium and lysosomal enzyme release from mouse calvaria in vitro. (Tullberg-Reinert H, Hefti AF) Agents Actions 1991 Mar;32(3-4):321-32 9 Citations |
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| 1 | Pathophysiology of vascular smooth muscle in renin promoter-T-antigen transgenic mice. (Sigmund CD, Jones CA, Jacob HJ, Ingelfinger J, Kim U, Gamble D, Dzau VJ, Gross KW) Am J Physiol 1991 Feb;260(2 Pt 2):F249-57 29 Citations |
| 1 | A new method for delivering alkanes to mammalian cells: preparation and preliminary characterization of an inclusion complex between beta-cyclodextrin and pristane (2,6,10,14-tetramethylpentadecane). (Janz S, Shacter E) Toxicology 1991;69(3):301-15 27 Citations |
| 1 | Modulation by thiols of the merocyanine 540-sensitized photolysis of leukemia cells, red cells, and herpes simplex virus type 1. (Gaffney DK, O'Brien JM, Sieber F) Photochem Photobiol 1991 Jan;53(1):85-92 31 Citations |
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| 1 | Isolation and characterization of renin-expressing cell lines from transgenic mice containing a renin-promoter viral oncogene fusion construct. (Sigmund CD, Okuyama K, Ingelfinger J, Jones CA, Mullins JJ, Kane C, Kim U, Wu CZ, Kenny L, Rustum Y) J Biol Chem 1990 Nov 15;265(32):19916-22 159 Citations |
| 1 | The N-terminal quarter of reovirus cell attachment protein sigma 1 possesses intrinsic virion-anchoring function. (Mah DC, Leone G, Jankowski JM, Lee PW) Virology 1990 Nov;179(1):95-103 37 Citations |
| 1 | Primary biliary cirrhosis in the mouse: induction by human mycoplasma-like organisms. (Johnson L, Wirostko E, Wirostko W) Int J Exp Pathol 1990 Oct;71(5):701-12 8 Citations |
| 1 | Rotaviruses specifically bind to the neutral glycosphingolipid asialo-GM1. (Willoughby RE, Yolken RH, Schnaar RL) J Virol 1990 Oct;64(10):4830-5 55 Citations |
| 1 | Expression of murine renin genes in subcutaneous connective tissue. (Sigmund CD, Jones CA, Mullins JJ, Kim U, Gross KW) Proc Natl Acad Sci U S A 1990 Oct;87(20):7993-7 26 Citations |
| 1 | Tissue and cell specific expression of a renin promoter-reporter gene construct in transgenic mice. (Sigmund CD, Jones CA, Fabian JR, Mullins JJ, Gross KW) Biochem Biophys Res Commun 1990 Jul 16;170(1):344-50 70 Citations |
| 1 | Polypeptide growth factors in metanephric growth and segmental nephron differentiation. (Avner ED, Sweeney WE Jr) Pediatr Nephrol 1990 Jul;4(4):372-7 78 Citations |
| 1 | Inter-tissue and inter-species characteristics of the mitochondrial carnitine palmitoyltransferase enzyme system. (Woeltje KF, Esser V, Weis BC, Cox WF, Schroeder JG, Liao ST, Foster DW, McGarry JD) J Biol Chem 1990 Jun 25;265(18):10714-9 99 Citations |
| 1 | DNA damage induced by phorbol ester-stimulated neutrophils is augmented by extracellular cofactors. Role of histidine and metals. (Shacter E, Lopez RL, Beecham EJ, Janz S) J Biol Chem 1990 Apr 25;265(12):6693-9 54 Citations |
| 1 | Adjunctive therapy (whole body hyperthermia versus lonidamine) to total body irradiation for the treatment of favorable B-cell neoplasms: a report of two pilot clinical trials and laboratory investigations. (Robins HI, Longo WL, Steeves RA, Cohen JD, Schmitt CL, Neville AJ, O'Keefe S, Lagoni R, Riggs C) Int J Radiat Oncol Biol Phys 1990 Apr;18(4):909-20 29 Citations |
| 1 | Expression of murine renin genes during fetal development. (Jones CA, Sigmund CD, McGowan RA, Kane-Haas CM, Gross KW) Mol Endocrinol 1990 Mar;4(3):375-83 111 Citations |
| 1 | A family of three mouse potassium channel genes with intronless coding regions. (Chandy KG, Williams CB, Spencer RH, Aguilar BA, Ghanshani S, Tempel BL, Gutman GA) Science 1990 Feb 23;247(4945):973-5 153 Citations |
| 1 | Carcinogenicity tests of fecapentaene-12 in mice and rats. (Weisburger JH, Jones RC, Wang CX, Backlund JY, Williams GM, Kingston DG, Van Tassell RL, Keyes RF, Wilkins TD, de Wit PP) Cancer Lett 1990 Feb;49(2):89-98 30 Citations |
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| 1 | In vitro modulation of tubular cyst regression in murine polycystic kidney disease. (Avner ED, Sweeney WE Jr, Ellis D) Kidney Int 1989 Dec;36(6):960-8 26 Citations |
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| 1 | Abundance of mRNAs encoding urea cycle enzymes in fetal and neonatal mouse liver. (Morris SM Jr, Kepka DM, Sweeney WE Jr, Avner ED) Arch Biochem Biophys 1989 Feb 15;269(1):175-80 38 Citations |
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| 1 | Gas chromatographic-mass spectrometric investigation of four commercial pristane (2.6.10.14-tetramethylpentadecane) preparations used for plasmacytoma induction in BALB/c mice. (Janz S, Birkenfeld T, Herzschuh R, Storch H) Arch Geschwulstforsch 1989;59(6):415-22 3 Citations |
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| 1 | The molecular genetics of Philadelphia chromosome-positive leukemias. (Kurzrock R, Gutterman JU, Talpaz M) N Engl J Med 1988 Oct 13;319(15):990-8 814 Citations |
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| 1 | Partial characterization and ontogeny of renal cytosolic glucocorticoid receptors in mouse kidney. (Ellis D, Turocy JF, Sweeney WE Jr, Avner ED) J Steroid Biochem 1986 May;24(5):997-1003 10 Citations |
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| 1 | The human cellular abl gene product in the chronic myelogenous leukemia cell line K562 has an associated tyrosine protein kinase activity. (Kloetzer W, Kurzrock R, Smith L, Talpaz M, Spiller M, Gutterman J, Arlinghaus R) Virology 1985 Jan 30;140(2):230-8 162 Citations |
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| 1 | Cyst formation in metanephric organ culture induced by cis-dichlorodiammineplatinum (II). (Avner ED, Sweeney WE Jr, Ellis D) Experientia 1983 Jan 15;39(1):74-6 9 Citations |
| 1 | Modulation of murine erythropoiesis in vitro by syngeneic thymocytes: interactions of enhancing and suppressing subpopulations with fluorescent anti-theta antibody and polyamino acids. (Sieber F, Sharkis SJ) Blood 1982 Oct;60(4):845-50 6 Citations |
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| 1 | Genetic control of the immune response to myoglobin. VI. Inter-site influences in T-lymphocyte proliferative response from analysis of cross-reactions of ten myoglobins in terms of substitutions in the antigenic sites and in environmental residues of the sites. (Atassi MZ, Yokota S, Twining SS, Lehmann H, David CS) Mol Immunol 1981 Oct;18(10):945-8 21 Citations |
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